Global ETD Search

11	Vergleich von monopolarer und bipolarer Präparationstechnik bei der radikaler retropubischer Prostatektomie hinsichtlich Komplikationsrate und perioperativer Morbidität. / Comparison of monopolar versus bipolar radical retropubic Prostatectomy. Complications and Morbidity. Przybyla, Andrzej 29 May 2012 (has links) No description available. 610 Medizin, Gesundheit Medizin Medicine Medizin
12	Morbidity and Discomfort of Ten-Core Biopsy of the Prostate Evaluated by Questionnaire Manseck, Andreas, Guhr, Karsten, Fröhner, Michael, Hakenberg, Oliver W., Wirth, Manfred P. 17 February 2014 (has links) (PDF) Transition zone biopsies have been found to increase the detection rates of cancer of the prostate in patients with negative digital rectal examination. There are however no data available whether the higher biopsy rate is associated with greater morbidity. The present study was therefore designed to evaluate the complication rate of extended sextant biopsy. In this prospective study, 162 consecutive patients who presented for prostatic evaluation were included. After starting prophylactic antibiotic treatment 48 h prior to the procedure, transrectal ultrasound-guided core biopsies were obtained from each lobe: three each from the peripheral zone (apex, mid-zone and base) and two from the transition zone of each prostatic lobe. In all patients a questionnaire was obtained 10–12 days after the procedure. Major complications occurred in 3 patients. In 2 of the 3 cases major macroscopic hematuria was treated by an indwelling catheter for 1 or 2 days and 1 patient developed fever >38.5°C for 1 day. Minor macroscopic hematuria was present in 68.5% of the patients. In 17.9% of these cases, the hematuria lasted for more than 3 days. Hematospermia was observed in 19.8% and minor rectal bleeding occurred in 4.9%. Ten-core biopsies did not lead to an increase in adverse effects or complications when compared to the results of sextant biopsies reported in the literature. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. Prostatakrebs Randzone Biopsie transrektale Prostatasonographie Morbidität prophylaktische Antibiotikaverabreichung Fragebogen Prostate cancer Transition zone biopsy Transrectal ultrasound Morbidity Prophylactic antibiotic treatment Questionnaire ddc:610 rvk:XA 10000
13	Peripheral Arterial Disease as an Independent Predictor for Excess Stroke Morbidity and Mortality in Primary-Care Patients: 5-Year Results of the getABI Study Meves, Saskia H., Diehm, Curt, Berger, Klaus, Pittrow, David, Trampisch, Hans-Joachim, Burghaus, Ina, Tepohl, Gerhart, Allenberg, Jens-Rainer, Endres, Heinz G., Schwertfeger, Markus, Darius, Harald, Haberl, Roman L. 26 February 2014 (has links) (PDF) Background:There is controversial evidence with regard to the significance of peripheral arterial disease (PAD) as an indicator for future stroke risk. We aimed to quantify the risk increase for mortality and morbidity associated with PAD. Methods:In an open, prospective, noninterventional cohort study in the primary care setting, a total of 6,880 unselected patients ≧65 years were categorized according to the presence or absence of PAD and followed up for vascular events or deaths over 5 years. PAD was defined as ankle-brachial index (ABI) <0.9 or history of previous peripheral revascularization and/or limb amputation and/or intermittent claudication. Associations between known cardiovascular risk factors including PAD and cerebrovascular mortality/events were analyzed in a multivariate Cox regression model. Results:During the 5-year follow-up [29,915 patient-years (PY)], 183 patients had a stroke (incidence per 1,000 PY: 6.1 cases). In patients with PAD (n = 1,429) compared to those without PAD (n = 5,392), the incidence of all stroke types standardized per 1,000 PY, with the exception of hemorrhagic stroke, was about doubled (for fatal stroke tripled). The corresponding adjusted hazard ratios were 1.6 (95% confidence interval, CI, 1.1–2.2) for total stroke, 1.7 (95% CI 1.2–2.5) for ischemic stroke, 0.7 (95% CI 0.2–2.2) for hemorrhagic stroke, 2.5 (95% CI 1.2–5.2) for fatal stroke and 1.4 (95% CI 0.9–2.1) for nonfatal stroke. Lower ABI categories were associated with higher stroke rates. Besides high age, previous stroke and diabetes mellitus, PAD was a significant independent predictor for ischemic stroke. Conclusions:The risk of stroke is substantially increased in PAD patients, and PAD is a strong independent predictor for stroke. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. ärztliche Grundversorgung Knöchel-Arm-Index periphere arterielle Verschlusskrankheit Schlaganfall Mortalität Morbidität Peripheral arterial disease Stroke mortality Stroke morbidity Ankle-brachial index Primary care ddc:610 rvk:XA 10000
14	Behandlungserfolg und Prognose des akuten Nierenversagens bei Patienten mit Sepsis und onkologischen Erkrankungen / Acute kidney injury (AKI) in the ICU: Outcomes from AKI in patients with sepsis and malignant diseases Mertens, Alexander 01 June 2017 (has links) No description available. 610 Akutes Nierenversagen Sepsis Maligne Neoplasien Komorbidität Prävalenz Morbidität acute kidney injury sepsis malignancies critical care outcomes
15	Temporal Changes in Alcohol-Related Morbidity and Mortality in Germany Kraus, Ludwig, Pabst, Alexander, Piontek, Daniela, Gmel, Gerrit, Shield, Kevin D., Frick, Hannah, Rehm, Jürgen 20 May 2020 (has links) Aims: Trends in morbidity and mortality, fully or partially attributable to alcohol, for adults aged 18–64 were assessed for Germany. Methods: The underestimation of population exposure was corrected by triangulating survey data with per capita consumption. Alcohol-attributable fractions by sex and two age groups were estimated for major disease categories causally linked to alcohol. Absolute numbers, population rates and proportions relative to all hospitalizations and deaths were calculated. Results: Trends of 100% alcohol-attributable morbidity and mortality over thirteen and eighteen years, respectively, show an increase in rates of hospitalizations and a decrease in mortality rates. Comparisons of alcohol-attributable morbidity including diseases partially caused by alcohol revealed an increase in hospitalization rates between 2006 and 2012. The proportion of alcohol-attributable hospitalizations remained constant. Rates of alcohol-attributable mortality and the proportion among all deaths decreased. Conclusions: The increasing trend in mortality due to alcohol until the mid-1990s has reversed. The constant proportion of all hospitalizations that were attributable to alcohol indicates that factors such as improved treatment and easier health care access may have influenced the general increase in all-cause morbidity. To further reduce alcohol-related mortality, efforts in reducing consumption and increasing treatment utilization are needed. info:eu-repo/classification/ddc/610 ddc:610 info:eu-repo/classification/ddc/150 ddc:150
16	Morbidity and Discomfort of Ten-Core Biopsy of the Prostate Evaluated by Questionnaire Manseck, Andreas, Guhr, Karsten, Fröhner, Michael, Hakenberg, Oliver W., Wirth, Manfred P. January 2001 (has links) Transition zone biopsies have been found to increase the detection rates of cancer of the prostate in patients with negative digital rectal examination. There are however no data available whether the higher biopsy rate is associated with greater morbidity. The present study was therefore designed to evaluate the complication rate of extended sextant biopsy. In this prospective study, 162 consecutive patients who presented for prostatic evaluation were included. After starting prophylactic antibiotic treatment 48 h prior to the procedure, transrectal ultrasound-guided core biopsies were obtained from each lobe: three each from the peripheral zone (apex, mid-zone and base) and two from the transition zone of each prostatic lobe. In all patients a questionnaire was obtained 10–12 days after the procedure. Major complications occurred in 3 patients. In 2 of the 3 cases major macroscopic hematuria was treated by an indwelling catheter for 1 or 2 days and 1 patient developed fever >38.5°C for 1 day. Minor macroscopic hematuria was present in 68.5% of the patients. In 17.9% of these cases, the hematuria lasted for more than 3 days. Hematospermia was observed in 19.8% and minor rectal bleeding occurred in 4.9%. Ten-core biopsies did not lead to an increase in adverse effects or complications when compared to the results of sextant biopsies reported in the literature. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. info:eu-repo/classification/ddc/610 ddc:610
17	Assoziation des PDCD1 rs11568821 GG-Genotyps mit stärkerer Morbidität bei Intensivpatienten mit Krankheitsbild Sepsis: Vergleich der SOFA-Sub-Scores / Association of the PDCD1 rs11568821 GG-genotype with higher morbidity of patients with sepsis at ICU: Comparison of the SOFA-sub-scores Gerber, Sebastian 30 June 2016 (has links) No description available. 610 Sepsis PD-1 PDCD1 rs11568821 Morbidität Intensivstation SOFA-Score GG-Genotyp Herz-Kreislauf-System Atmung ZNS Sepsis PD-1 PDCD1 rs11568821 morbidity ICU SOFA-Score GG-genotype cardiovascular system respiration CNS Medizin (PPN619874732)
18	Peripheral Arterial Disease as an Independent Predictor for Excess Stroke Morbidity and Mortality in Primary-Care Patients: 5-Year Results of the getABI Study Meves, Saskia H., Diehm, Curt, Berger, Klaus, Pittrow, David, Trampisch, Hans-Joachim, Burghaus, Ina, Tepohl, Gerhart, Allenberg, Jens-Rainer, Endres, Heinz G., Schwertfeger, Markus, Darius, Harald, Haberl, Roman L. January 2010 (has links) Background:There is controversial evidence with regard to the significance of peripheral arterial disease (PAD) as an indicator for future stroke risk. We aimed to quantify the risk increase for mortality and morbidity associated with PAD. Methods:In an open, prospective, noninterventional cohort study in the primary care setting, a total of 6,880 unselected patients ≧65 years were categorized according to the presence or absence of PAD and followed up for vascular events or deaths over 5 years. PAD was defined as ankle-brachial index (ABI) <0.9 or history of previous peripheral revascularization and/or limb amputation and/or intermittent claudication. Associations between known cardiovascular risk factors including PAD and cerebrovascular mortality/events were analyzed in a multivariate Cox regression model. Results:During the 5-year follow-up [29,915 patient-years (PY)], 183 patients had a stroke (incidence per 1,000 PY: 6.1 cases). In patients with PAD (n = 1,429) compared to those without PAD (n = 5,392), the incidence of all stroke types standardized per 1,000 PY, with the exception of hemorrhagic stroke, was about doubled (for fatal stroke tripled). The corresponding adjusted hazard ratios were 1.6 (95% confidence interval, CI, 1.1–2.2) for total stroke, 1.7 (95% CI 1.2–2.5) for ischemic stroke, 0.7 (95% CI 0.2–2.2) for hemorrhagic stroke, 2.5 (95% CI 1.2–5.2) for fatal stroke and 1.4 (95% CI 0.9–2.1) for nonfatal stroke. Lower ABI categories were associated with higher stroke rates. Besides high age, previous stroke and diabetes mellitus, PAD was a significant independent predictor for ischemic stroke. Conclusions:The risk of stroke is substantially increased in PAD patients, and PAD is a strong independent predictor for stroke. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. info:eu-repo/classification/ddc/610 ddc:610
19	Verbesserung der medizinischen Versorgung und des Outcomes sehr kleiner und leichter Frühgeborener durch klinisches Benchmarking Bätzel, Carolin 04 April 2006 (has links) In der vorliegenden Arbeit wurde anhand der im Rahmen des Vermont-Oxford-Neonatal-Networks erhobenen Daten an der Berliner Klinik für Neonatologie der Charité Campus Mitte und der Abteilung für neonatologische Intensivmedizin der Universitätskinderklinik in Innsbruck ein Benchmarking-Projekt für die Jahre 1997 bis 2001 durchgeführt. Nach der Analyse des Outcomes wurde eine Analyse der externen Evidenz anhand von Literatursuche in PubMed und der Cochrane Datenbank für systematische Reviews durchgeführt. Danach wurde ein Fragebogen entworfen, der gezielt Handlungsstrategien und -richtlinien bezüglich der relevanten Outcome-Parameter erfragt. Für das Benchmarking-Projekt wurden das Atemnotsyndrom, die nekrotisierende Enterokolitis und die bakteriellen Infektionen ausgewählt. Die Analyse der Handlungsstrategien durch den Fragebogen zeigte, dass in den drei Bereichen respiratorische Interventionen, Nahrung und Ernährung sowie im Infektionsmanagement Unterschiede vorlagen. In der Diskussion zeigte sich, dass in vielen Bereichen noch Bedarf nach guter externer Evidenz und weiterer Forschung besteht. / This dissertation presents the results of a 1997 - 2001 benchmark project in co-operation with the "Berliner Klinik für Neonatologie der Charité Campus Mitte" and the "Abteilung für neonatologische Intensivmedizin der Universitätskinderklinik" in Innsbruck. The study is based on the Vermont-Oxford-Neonatal-Network''s data. After analysing the results, further evidence was analysed by way of literary research in PubMed and the Cochrane Database of Systematic Reviews. Afterwards, a questionnaire was created, lining out the clinical guidelines of the relevant outcome parameters. The respiratory distress syndrom, the necrotising enterocolitis and the bacterial infections were selected for the benchmark. The internal guidelines'' analysis showed that there were differences between the two clinics'' results in respiratory interventions, feeding and the management of infections. The discussion made clear that research based on further evidence is necessary in many fields. Sepsis Qualitätsmanagement Benchmarking Handlungsrichtlinien Vermont-Oxford-Neonatal-Network very-low-birth-weight-Frühgeborene chronische und akute Morbidität Atemnotsyndrom nekrotisierende Enterokolitis bakterielle Infektionen respiratorische Interventionen Nahrung und Ernährung Infektionsmanagement Liegedauer Sauerstoffgrenzwert Surfactanttherapie Thrombozytengrenzwert Thrombozytopnie Pasteurisierung von Muttermilch Heparinisierung Antibiotikaprophylaxe sepsis benchmarking management of quality guidelines Vermont-Oxford-Neonatal-Network very-low-birth-weight neonates chronic and akute morbidity respiratory distress syndrome necrotising enterocolitis bacterial infections respiratory interventions feeding management of infections length of stay thrombocytopenia platelet count 610 Medizin 33 Medizin YQ 2404 YQ 2415 ddc:610

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