Made available in DSpace on 2016-04-18T12:12:32Z (GMT). No. of bitstreams: 15 Ricardo Luis Silva1.pdf: 3940901 bytes, checksum: bd950ce9ddc935c85502004dfee7f324 (MD5) Ricardo Luis Silva2.pdf: 2135438 bytes, checksum: dc04ba1f03a54da0d31f3a31844543ea (MD5) Ricardo Luis Silva3.pdf: 2078321 bytes, checksum: d38415c9a87f1cd57e90c45d325824a0 (MD5) Ricardo Luis Silva4.pdf: 2096546 bytes, checksum: a2e7d4452aa20b83f68a0d0749fd2efd (MD5) Ricardo Luis Silva5.pdf: 3146651 bytes, checksum: 8d81feb001e6e659a35ec59f664db8d1 (MD5) Ricardo Luis Silva6.pdf: 1975681 bytes, checksum: 51771caae30704fd3de6ced7587731d5 (MD5) Ricardo Luis Silva7.pdf: 1572528 bytes, checksum: 4450569fece868dc7c55b60853a24161 (MD5) Ricardo Luis Silva8.pdf: 2403329 bytes, checksum: 32f4836dbcf315d7588479b889d85d87 (MD5) Ricardo Luis Silva9.pdf: 3078211 bytes, checksum: b8dc849f9d71a4194d163679ecf56321 (MD5) Ricardo Luis Silva10.pdf: 1946003 bytes, checksum: a883983c79e5b40f18d7c3a6ef8f362c (MD5) Ricardo Luis Silva11.pdf: 3281835 bytes, checksum: ec5c269cf14691410783714b0af6f5c0 (MD5) Ricardo Luis Silva12.pdf: 3196600 bytes, checksum: 35de7b52b251af69542d31533f0288ba (MD5) Ricardo Luis Silva13.pdf: 3284221 bytes, checksum: 5c6e42fd0c7d148336756ade909e88eb (MD5) Ricardo Luis Silva14.pdf: 3325569 bytes, checksum: e908d96c75e4ea795cb3d2865fc6c9b0 (MD5) Ricardo Luis Silva15.pdf: 1656213 bytes, checksum: 6c01d346358713f62a6edf2a19dd0de6 (MD5) Previous issue date: 2009-02-02 / Fundo Mackenzie de Pesquisa / This paper discusses possibilities of reading a contemporary metropolis, represented here by the city of São Paulo. To do this, an icon in the city was chosen to simulate those possible readings. This object is the São Vito building, or "treme-treme", a sample of the chaotic organization and development who insists to remain rooted in the paulistanian territory. And to accomplish this task of reading, I adopted and absorbed a fundamental concept in contemporary philosophy: the rhizome. With this concept in mind, the subjects were formatted in the form of letters of the alphabet, creating a dictionary, or rather, a rhizomatous abecedarian. During its development, this work has turned into a documentation. A documentation of processes, pathways, the usually marginalized elements of academic studies over the city, about really experiencing the city. Take the city for yourself, viscerally. In the end, this work clarifies a further possibility of reading and ownership of this complex and instigating entity that is São Paulo, without, of course, ignore or discredit those traditional ways to realize such readings. It just tried to think about how to read the city. A reading more open, derivative and rhizomatous. / Este trabalho aborda possibilidades de leitura de uma metrópole contemporânea, representada neste caso pela cidade de São Paulo. Para tal, um ícone presente na cidade foi escolhido para simular essas possíveis leituras. Este objeto é o edifício São Vito, ou treme-treme , uma amostra da organização e do desenvolvimento caótico que insiste em permanecer enraizado no território paulistano. E para realizar essa empreitada de leitura, tomei a liberdade de adotar e absorver um conceito fundamental na filosofia contemporânea: o rizoma. Com esse conceito em mente, os temas foram formatados em forma de letras do alfabeto, criando um dicionário, ou melhor, um abecedário rizomático. Durante seu desenvolvimento, este trabalho se transformou em uma documentação. Uma documentação sobre os processos, os percursos, os elementos normalmente marginalizados dos estudos acadêmicos sobre a cidade, sobre o vivenciar realmente a cidade. Apropriar-se, visceralmente. E, no fim, este trabalho explicita uma outra possibilidade de leitura e apropriação desta complexa e instigante entidade que é São Paulo, sem, é claro, desconsiderar ou desqualificar as ditas maneiras clássicas e estabelecidas de realizar tal leitura. Apenas procurou-se refletir sobre ler a cidade de uma forma mais aberta, derivática e rizomática.

A presente dissertação tem como objeto o estudo das obrigações propter rem e figuras correlatas. Os grandes civilistas dedicaram-se ao tema que será desenvolvido neste trabalho; o assunto não é inédito, muito ao contrário. Contudo, vários pontos permanecem controversos, até mesmo quanto à própria definição e alcance da noção de obrigação real. A importância da matéria não se resume a uma discussão acadêmica, meramente abstrata. Em realidade, o instituto é extremamente recorrente na doutrina e jurisprudência. Ocorre que, considerada a confusão conceitual que caracteriza essa espécie de obrigação, verifica-se que o instituto serve de fundamento a diversas decisões, muitas delas sem precisão técnica necessária. Decerto, criam-se vínculos e deveres sem que exista uma lei específica nesse sentido, sob o simples argumento de que se trata de uma obrigação propter rem. Não bastasse, são atribuídos determinados efeitos a essas obrigações, os quais não são necessariamente essenciais ao instituto. Nesse contexto, consideramos que uma releitura do conceito de obrigação real é oportuna e pode contribuir para um tratamento mais adequado de uma série de questões. / This dissertation discusses the propter rem obligations and related legal aspects. The propter rem obligations are not a new topic and it was studied by all main civil law scholars. However, there are a many unsolved matters related to such obligations, including its exact definition and extension. The relevance of propter rem obligations is not limited to an academic debate; in fact it is a recurring matter by commentators and court precedents. Due to the conceptual misunderstanding as to the correct definition of propter rem obligations, this concept has been mistakenly used in several court decisions. Courts are creating legal obligations without proper legislation, based solely on the argument that such obligations are based on the propter rem principles, including the attribution of supposed legal effects not related to these obligations. In this context, we believe it is important to revisit the concept of the propter rem obligations to promote a better understanding of several issues.

Submitted by Renata Lopes (renatasil82@gmail.com) on 2016-04-29T14:10:20Z No. of bitstreams: 1 alvaroluizbarbosaribeiro.pdf: 1291639 bytes, checksum: 81eaeecf3aa21a06d4e57732422e5484 (MD5) / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2016-05-02T01:20:23Z (GMT) No. of bitstreams: 1 alvaroluizbarbosaribeiro.pdf: 1291639 bytes, checksum: 81eaeecf3aa21a06d4e57732422e5484 (MD5) / Made available in DSpace on 2016-05-02T01:20:23Z (GMT). No. of bitstreams: 1 alvaroluizbarbosaribeiro.pdf: 1291639 bytes, checksum: 81eaeecf3aa21a06d4e57732422e5484 (MD5) Previous issue date: 2014-09-30 / O presente trabalho tem como objeto de estudo a fase inicial do programa Reinventando o Ensino Médio, do governo de Minas Gerais. O objetivo é analisar a implementação desse programa nas escolas que fazem parte do seu projeto-piloto. Por isso, foram destacadas duas escolas, onde procurou-se verificar como as ações gestoras podem influenciar positivamente o êxito de um programa de governo, assim como examinar a importância dos gestores na instituição escolar e no sucesso do processo educativo-pedagógico. A metodologia de pesquisa utilizada foi a análise de documentos relativos ao referido programa, e o perfil dos alunos, por meio dos resultados das avaliações externas realizadas pelo CAEd/UFJF; além de entrevistas semiestruturadas, com diretores, coordenadores, orientadores e alunos de turmas iniciais do REM, nessas duas escolas selecionadas. Contou, ainda, com a observação do cotidiano escolar por meio de visitas in loco, onde foram aferidas informações importantes sobre a atuação do gestor escolar e os resultados das ações desenvolvidas nessa fase do Programa. A expectativa é de que ao final desse estudo, possam ser identificadas as ações das escolas que contribuem com a melhoria contínua dos resultados, bem como, as dificuldades encontradas pela equipe gestora das duas escolas no desenvolvimento do programa. Este trabalho pretende ainda ressaltar em seu PAE alguns aspectos, no sentido de promover condições favoráveis de utilização dos fatos observados, e melhorar a eficácia de algumas ações dentro das escolas participantes. / This work has as its object of study the initial phase of the program Reinventing Secondary Education, Government of Minas Gerais. The objective is to analyze the implementation of this program in schools that are part of its pilot project. Therefore, two schools were highlighted, where it was examined how management actions can positively influence the success of a government program, as well as examining the importance of managers in schools and the success of the education-learning process. The research methodology used was the analysis of documents relating to that program, and the profile of the students, through the results of external evaluations conducted by CAEd / UFJF; well as semi-structured interviews with directors, coordinators, advisors and students and starting classes REM, in these two selected schools. Also relied on the observation of daily school through visits, where important information on the role of school management and the results of actions taken in this phase of the program were measured. The expectation is that at the end of this study, the actions of schools that contribute to continuous improvement of the results can be identified as well as the difficulties encountered by the management staff of the two schools in program development. This work intends to highlight on your PAE some aspects, to promote favorable conditions for the use of the observed facts, and improve the effectiveness of some actions within the participating schools.

To solve the spectrum scarcity problem caused by the high number of wireless applications and users, the concept of cognitive radio (CR) was proposed in the past few years. Cognitive radio networks (CRNs) provide dynamic spectrum access (DSA), where the unlicensed users can access the spectrum without causing unacceptable level of interference to the primary user (PU). DSA was based on conventional spectrum sensing information or geolocation databases. Later, radio environment map (REM) as an improved geolocation database was introduced to enhance the DSA process. It is a comprehensive map consists of different integrated databases, and the interference field information is one of its databases. In this thesis, a description of the REM concept and its construction methods will be presented. The focus will be for the indirect methods for constructing interference map, which represents a layer of the REM. Indirect method refers to the methods that utilize known model information, to first estimate the primary transmitter parameters and then generate REM. Two indirect methods under lognormal shadowing were presented and compared. The better of these two methods is further investigated in different scenarios. These scenarios include different number of sensors, varied size of measurements, several shadowing spread values, different percentages of error in path-loss exponent, and the effect of the number of moving sensors and their speeds to the REM quality. The performance is evaluated using these metrics: “localization error, signal power error and correct detection zone ratio (CDZR). The results show that performance is enhanced as the number of sensors and the size of measurements increase, whereas clear degradation in REM quality is shown when shadowing spread increases or the model parameters are not well calibrated. Also, as the number of moving sensors or their speeds increase, the REM performance becomes less effective

The diagnosis of Parkinson’s disease (PD) follows the UK Brain Bank Criteria, which demands bradykinesia and one additional symptom, i.e. rigidity, resting tremor or postural instability. The latter is not a useful sign for the early diagnosis of PD, because it does not appear before Hoehn and Yahr stage 3. Early symptoms of PD which precede the onset of motor symptoms are hyposmia, REM sleep behavioral disorder, constipation, and depression. In addition, an increasing number of patients whose PD is related to a genetic defect are being described. Thus, genetic testing may eventually develop into a tool to identify at-risk patients. The clinical diagnosis of PD can be supported by levodopa or apomorphine tests. Imaging studies such as cranial CT or MRI are helpful to distinguish idiopathic PD from atypical or secondary PD. SPECT and PET methods are valuable to distinguish PD tremor from essential tremor if this is clinically not possible. Using all of these methods, we may soon be able to make a premotor diagnosis of PD, which will raise the question whether early treatment is possible and ethically and clinically advisable. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.

Physikalische und chemische Charakterisierung von Lithiumionenzellen

REM sleep behavior disorder: Characteristics of polysomnographic and behavioral manifestations Abstract REM sleep behavior disorder (RBD) is a disease characterized by abnormal motor activity corresponding to the dream content. REM sleep without atonia (RWA) and behavioral manifestations are the main features registered by video-polysomnography (PSG). Because idiopathic RBD (iRBD) is considered as prodromal stage of synucleinopathies, the direction of current research is the search for markers of early conversion. The goal of this study was to observe the group of patients with iRBD with regard to the development of manifest neurodegenerative disease, to find and test a new polysomnographic marker of phenoconversion, to perform analysis of the movements registered by video and to quantify excessive fragmentary myoclonus (EFM), which is a frequent finding in neurodegenerative processes. A total of 55 patients with iRBD were observed for 2.3±0.7 years. The annual conversion rate was 5.5%. Mixed RWA, representing simultaneous occurrence of phasic and tonic RWA, was suggested as a new marker of phenoconversion. Converted patients showed a higher mixed RWA (p=0.009) and the ROC analysis confirmed that mixed RWA is the best predictive marker of conversion among other RWA types (AUC 0.778). An average of...

A leading theory for why we sleep focuses on memory consolidation - the process of stabilizing and strengthening newly acquired memories into long-term storage. Consolidation of memory for cognitive strategies and problem-solving skills is enhanced as compared to a period of daytime wakefulness. Importantly, sleep preferentially enhances memory for the cognitive strategy per se, over-and-above the motor skills that are used to execute the strategy. Although it has been known for some time that sleep benefits this type of memory, it is not known how this process unfolds during sleep, or how sleep transforms this memory trace in the brain. Sleep is classified into rapid eye movement (REM) sleep and non-REM (NREM) sleep. The role of REM sleep for consolidation of memory for problem-solving skills remains controversial. In addition, little attention has been paid to the possible distinct roles of phasic REM sleep (i.e., when bursts of eye movements occur) and tonic REM sleep (i.e., the presence of isolated eye movements and the absence of eye movement bursts). REM sleep might favour procedural memory consolidation for cognitive strategies and problem-solving skills, and the specific role of REM sleep in this process might be discernible only by differentiating between phasic and tonic REM states. In addition, fMRI studies have revealed that sleep-related consolidation of the memory trace for simple motor procedural skills is associated with strengthened activity of, and functional connectivity between, key memory-related brain areas (i.e., hippocampal, striatal, and neocortex). However, fMRI techniques have not yet been employed to investigate sleep-related consolidation of procedural memory for cognitive strategies and problem-solving skills. Participants (n=60) performed a procedural memory task involving a cognitive strategy while undergoing functional magnetic resonance imaging (fMRI) before and after a condition of Sleep, Nap, or Wake. Those in the Sleep and Nap condition underwent polysomnography (PSG) to further study the learning-related changes in sleep macrostructure and microstructure. This thesis not only shows that a period of sleep or a nap afford a greater benefit to memory consolidation of a procedural strategy than a period of wake, but more specifically: In Study 1, during sleep, phasic REM sleep theta power was directly associated with overnight improvement on the task, whereas tonic REM sleep sensorimotor rhythm power was greater following a night of learning compared to a non-learning control night. In Study 2, we show that distinct hippocampal, striatal, and cortical areas associated with strategy learning are preferentially enhanced. Study 3 reveals that the functional communication among these brain areas is greater following sleep compared to a daytime nap or day of wakefulness. Sleep-related changes in brain activation and functional connectivity were both correlated with improved performance from before to after a period of sleep. Overall, findings from this thesis support the benefit of sleep at the behavioural and systems level for consolidating procedural memory involving cognitive strategies used to solve problems. The findings suggest that the multifaceted nature of REM sleep must be examined separately by its phasic and tonic states, to identify the active role of REM sleep for consolidating memory. Further, the consolidation of the memory trace is reflected through activation of, and communication between hippocampal, striatal, and neocortical brain areas. In summary, this thesis shows that sleep actively consolidates memory for cognitive strategies and problem-solving skills.

Att köra fastän trötthet upplevs är en erkänd trafikfara. Om en förare idag kör när denne är trött klassas det som vårdslöshet i trafiken. Dock är det nästan omöjligt att vid en olycka påvisa att olyckan skedde för att en förare var trött. Det praktiska resultatet är att det lämnas åt föraren att själv avgöra om denne är för trött för att föra fram fordonet säkert. Hela situationen om att vara en trafikfara eller ej lämnas då åt en subjektiv bedömning.   I denna rapport undersöks olika sömnstadier, och metoder för att avgöra när och hur det är lämpligast att vakna för att vakna i ett mer alert tillstånd. För att sedan använda de metoder som visar sig vara lämpade som indata och parametrar till en algoritm som ska avgöra när det är som lämpligast att vakna för att vakna mer alert. Rapporten gör också en kalkyl som kan användas för att fastställa prototypens utvecklingskostnader.   Arbetet resulterar i en prototyp som föreslår en lösning till problemet med trötthet i trafiken. De kostnader som framkommer i samband med prototyputveckling fastställs och presenteras.   Undersökningen och utvecklandet av den tekniska lösningen har delats upp i två moduler och kommer att göras i samverkan med en extern studentgrupp på skolan för elektroteknik och datavetenskap (EECS) vid Kungliga Tekniska högskolan. / Driving although experiencing fatigue is a recognized traffic hazard. Today, if a driver is driving despite being tired, it is considered to be reckless driving. However, in the event of an accident, it is almost impossible to prove that the accident occurred because the driver was tired. The practical result is that it is left to the driver to decide if one is too tired or not to drive the vehicle safely. The whole situation of being a traffic hazard or not is then subjected to a subjective assessment. This report examines different sleep stages and methods for determining when it’s most appropriate, and how it’s most appropriate to wake up, with the aim on waking up in a more alert state. Further, to use the methods that prove to be suitable as inputs and parameters of an algorithm. The report also examines different calculations that can be used to determine the development cost of the prototype. The result consists of a prototype that is a beginning on addressing the problem with fatigue in traffic. It also consist of a calculation determining the development cost. The research and development of the technical solution has been divided into two modules and will be done in collaboration with an external student group at School of Electrical Engineering and Computer Science (EECS) at KTH Royal Institute of Technology.

Mouse mammary tumor virus (MMTV) is a betaretrovirus that causes mammary tumors in mice. MMTV is the only known complex murine retrovirus and encodes Rem, an HIV-1 Rev-like protein. Rem is a 301-amino-acid (33 kDa) protein that is cotranslationally targeted to the ER, where the first 98 amino acids constitute the signal peptide (SP). The SP is cleaved and retrotranslocated to the cytoplasm prior to nuclear entry. In this thesis, the results show that the presence of a leucine at position 71 allows more efficient cleavage of SP and increases Rem activity. Further, in Rem-transfected cells, the majority of SP appears in the nuclear fraction, consistent with fluorescent microscopy data. The C-terminal fragment of Rem (RemCT) is glycosylated in the ER and, although glycosylation sites are present outside the SP, mutations of both these sites abolish SP activity in a reporter assay. Indirect evidence suggests that unglycosylated RemCT is degraded by the proteasome, whereas glycosylated RemCT is likely secreted out of the cell. A variant of MMTV (TBLV) that lacks functional Sag and RemCT has been prepared and will be studied in mice to elucidate the role of RemCT in vivo. Development of an antibody to RemCT will allow tracking of the protein in virus-producing cells. Although there are many other similarities between complex retroviruses like HIV-1 and MMTV, current evidence suggests that Rem lacks an HIV Tat-like transactivator function. / text