Made available in DSpace on 2016-04-26T20:27:00Z (GMT). No. of bitstreams: 1 Gustavo Portela Barata de Almeida.pdf: 1184077 bytes, checksum: 92f2702de4adad33e5a88c9209895331 (MD5) Previous issue date: 2008-04-09 / The present research has been originated with the objective of verifying the applicability or not of the rules contained in the Law of Penal Execution and the reflexes of this inapplicability or partial applicability in the life of the cloistered and the prison egress. The work was based on field researches done at Sorocaba s Criminal Execution s Trial Court and with the local prison directors and the cloistered and egresses of these prisons. In the first chapter we have outlined the evolution of the penalty and its finality. In the second chapter we have analyzed the main rules contained at the LEP (Law of Penal Execution) regarding the assistance of the rights assured to the imprisoned, as well as analyzed the attributions destined to the execution organs. On chapter three we presented the actual research and in the last chapter we have outlined a parallel between what is established by law and the reality experienced in prison quotidian. Different means of confrontation and prove are brought to quote where we can conclude to be a reduction of the finality and reach the norms asserted in the Law of Penal Execution, despite its non applicability by means of the governmental organs in a way to become a dead letter inside the current legal injunction / O presente estudo originou-se com objetivo de se verificar a aplicabilidade ou não das regras contidas na Lei de Execução Penal e os reflexos desta inaplicabilidade - ou aplicabilidade parcial - na vida do recluso e egresso do cárcere. O trabalho foi alicerçado em pesquisa de campo realizado junto ao Juízo das Execuções Criminais de Sorocaba, diretores de presídios locais, reclusos e egressos destes mesmos estabelecimentos prisionais. No primeiro capítulo traçamos a evolução da pena e sua finalidade. Posteriormente no segundo capítulo analisamos as principais regras contidas na LEP acerca da assistência de direitos assegurados aos presos, bem como analisamos as atribuições destinadas aos órgãos da execução. No capitulo terceiro apresentamos a efetiva pesquisa e, por fim no ultimo capitulo traçamos um paralelo entre o estabelecido pela Lei e a realidade vivenciada no cotidiano dos estabelecimentos prisionais. São aqui trazidos à colação diferentes meios de confrontamento e prova donde podemos concluir haver uma diminuição da finalidade e alcance das normas preceituadas na Lei de Execuções Penais, posto a sua não-aplicabilidade por meio dos órgãos governamentais, de modo a ter-se tornado letra morta dentro do ordenamento jurídico vigente

Made available in DSpace on 2016-04-26T20:23:21Z (GMT). No. of bitstreams: 1 Reynaldo Soares da Fonseca.pdf: 2365868 bytes, checksum: 2d3ae3835ac590ad647db9c4d5d1037a (MD5) Previous issue date: 2014-10-23 / When the 1988 Brazilian Constitution came into force, a new social-political boundary was established, conferring to the judiciary branch a huge number of constitutional powers, in order to allow it to act as a guarantor of democracy and fundamental rights. In fact, there is an explicit framework of dysfunctionalities in the judicial power, i.e., there is a vast difference between what was written in the Constitution and the judicial activity provided by the Judiciary branch, considering the legal possibilities and facts historically observed. According to data from the National Council of Justice, there are more than 92.2 millions pending cases in Brazil. In the Federal Courts, there are more than 11.5 million cases, involving paramount questions related to citizenship (dwelling, social security, health, education, etc). Therefore, the due process clause is revisited, founded in the principle of fraternity and Normative Legal Humanism, in order to find out mediation as a great alternative to resolve disputes in the Federal Courts in Brazil / No marco sócio-político brasileiro, com a entrada em vigor da Constituição da República Federativa do Brasil, em 1988, ocorre uma conferência vultosa de poderes constitucionais ao Poder Judiciário, a fim de que este atue como fiador da democracia e garantidor dos direitos fundamentais. Na realidade, tem-se explicitamente um quadro de disfuncionalidades do Poder judicante, isto é, há uma diferença abissal entre o que o Poder Constituinte positivou na Carta Maior e a atividade jurisdicional que, de fato, o Judiciário presta, à luz das possibilidades jurídicas e fáticas observáveis na concretude histórica. Segundo os dados do Conselho Nacional de Justiça, há mais de 92,2 milhões de processos em tramitação no Poder Judiciário Brasileiro. Na Justiça Federal, tramitam mais de 11,5 milhões de processos, envolvendo questões vitais da cidadania (habitação, previdência, saúde, educação, etc.). Assim, revisita-se o princípio do devido processo legal, com alicerce no princípio da fraternidade e no jus-humanismo normativo, para apontar a conciliação como uma grande alternativa para o acesso e a saída da Justiça Federal brasileira

Le virus herpès simplex de type 1 (HSV 1) affecte la majorité de la population mondiale. HSV 1 cause de multiples symptômes délétères dont les plus communs sont les lésions orofaciales usuellement appelées feux sauvages. Le virus peut aussi causer des effets plus sérieux comme la cécité ou des troubles neurologiques. Le virus réside de façon permanente dans le corps de son hôte. Malgré l’existence de nombreux traitements pour atténuer les symptômes causés par HSV 1, aucun médicament ne peut éliminer le virus. Dans le but d’améliorer les connaissances concernant le cycle viral de HSV 1, ce projet cible l’étude du transport du virus dans la cellule hôte. Ce projet aura permis la collecte d’informations concernant le modus operandi de HSV 1 pour sortir des compartiments cellulaires où il séjourne. Les différentes expérimentations ont permis de publier 3 articles dont un article qui a été choisi parmi les meilleurs papiers par les éditeurs de « Journal of Virology » ainsi qu’un 4e article qui a été soumis. Premièrement, un essai in vitro reproduisant la sortie de HSV 1 du noyau a été mis sur pied, via l’isolation de noyaux issus de cellules infectées. Nous avons démontré que tout comme dans les cellules entières, les capsides s’évadent des noyaux isolés dans l’essai in vitro en bourgeonnant avec la membrane nucléaire interne, puis en s’accumulant sous forme de capsides enveloppées entre les deux membranes nucléaires pour finalement être relâchées dans le cytoplasme exclusivement sous une forme non enveloppée. Ces observations appuient le modèle de transport de dé-enveloppement/ré-enveloppement. Deuxièmement, dans le but d’identifier des joueurs clefs viraux impliqués dans la sortie nucléaire du virus, les protéines virales associées aux capsides relâchées par le noyau ont été examinées. La morphologie multicouche du virus HSV 1 comprend un génome d’ADN, une capside, le tégument et une enveloppe. Le tégument est un ensemble de protéines virales qui sont ajoutées séquentiellement sur la particule virale. La séquence d’ajout des téguments de même que les sites intracellulaires où a lieu la tégumentation sont l’objet d’intenses recherches. L’essai in vitro a été utilisé pour étudier cette tégumentation. Les données recueillies suggèrent un processus séquentiel qui implique l’acquisition des protéines UL36, UL37, ICP0, ICP8, UL41, UL42, US3 et possiblement ICP4 sur les capsides relâchées par le noyau. Troisièmement, pour obtenir davantage d’informations concernant la sortie de HSV 1 des compartiments membranaires de la cellule hôte, la sortie de HSV 1 du réseau trans golgien (TGN) a aussi été étudiée. L’étude a révélé l’implication de la protéine kinase D cellulaire (PKD) dans le transport post-TGN de HSV 1. PKD est connue pour réguler le transport de petits cargos et son implication dans le transport de HSV 1 met en lumière l’utilisation d’une machinerie commune pour le transport des petits et gros cargos en aval du TGN. Le TGN n’est donc pas seulement une station de triage, mais est aussi un point de rencontre pour différentes voies de transport intracellulaire. Tous ces résultats contribuent à une meilleure compréhension du processus complexe de maturation du virus HSV 1, ce qui pourrait mener au développement de meilleurs traitements pour combattre le virus. Les données amassées concernant le virus HSV 1 pourraient aussi être appliquées à d’autres virus. En plus de leur pertinence dans le domaine de la virologie, les découvertes issues de ce projet apportent également de nouveaux détails au niveau du transport intracellulaire. / Herpes simplex virus type 1 (HSV 1) affects the majority of the world population. HSV 1 causes various deleterious symptoms with the most common being facial mucosal lesions usually named cold sores. The virus can also contribute to more serious effects such as corneal blindness and neurological problems. The virus is permanently residing in the host body. Despite the existence of several treatments against HSV 1 symptoms, no drug is able to eliminate the virus. In order to improve knowledge of the viral cycle of HSV 1, this project focuses on the transport of the virus in the host cell. During this project we collect data to detail the modus operandi used by HSV 1 to leave cellular compartments such as the nucleus and the TGN. The different experimentations achieved during this PhD allowed the publication of three articles, including one selected as worthy of note by the editors of “Journal of virology” and a fourth article that has been submitted. Firstly, an in vitro assay that reproduces the exit of HSV 1 virus from nuclei was established via the isolation of nuclei from infected cells. We found that, as in intact cells, capsids escaped the isolated nuclei in the in vitro assay by budding through the inner nuclear membrane, accumulated as enveloped capsids between the two nuclear membranes, and were released in cytoplasm exclusively as unenveloped capsids. These observations support the de-envelopment / re-envelopment model of transport. Secondly, to identify viral players implicated in the nuclear egress of HSV 1, viral proteins associated with nuclear released capsids were investigated. HSV 1 has a multilayered morphology that includes a DNA genome, a capsid, a tegument and an envelope. The tegument represents viral proteins added sequentially on the viral particle. The sequential order and intracellular compartments where the tegument is added are the subject of intense research. The in vitro assay was used to investigate this tegumentation process. The acquired data suggest a sequential process that involved the acquisition of viral proteins UL36, UL37, ICP0, ICP8, UL41, UL42, US3 and possibly ICP4 on capsids released by the nucleus. Thirdly, to obtain information regarding another process of egress of HSV 1 from a membranous cellular organelle, the egress of HSV 1 from the TGN was also studied. The study revealed the implication of the cellular protein kinase D (PKD) in HSV 1 post-TGN transport. The involvement of this kinase, known to regulate the transport of small cargos, highlights the post TGN trafficking of both small and large entities (such as HSV 1) by a common machinery, in sharp contrast to earlier steps of transport. This indicates that the TGN is not only a sorting station but also a meeting point where different intracellular routes can meet. All these outcomes contribute to a better understanding of the complex maturation process of HSV 1 that could lead to the development of better tools to fight the virus. Results acquired concerning HSV 1 could also be applied to other viruses. Besides their relevance in the virology field, findings provided by this project also supply new details about cellular biology concerning intracellular transport.

In the modern era there exist applications that require very high resources and generate a tremendous amount of traffic so they require considerable amount of bandwidth and QOS to operate and perform correctly. MPLS is a new and a fast technology that offers much remuneration both in terms of providing trouble-free and efficient security together with the high speed of switching. MPLS not only guarantees quality of service of IP networks but in addition to provides scope for traffic engineering it offers many enhanced features of IP networks as it does not replace IP routing, but works along with existing and future routing technologies to provide high-speed data forwarding between label-switched routers (LSRs) together with QOS. Many network carriers are facing the problem of how to accommodate such ever-growing demands for bandwidth. And the static nature of current routing algorithms, such as OSPF or IS-IS, the situation is going even worse since the traffic is concentrated on the "least cost" paths which causes the congestion for some links while leaving other links lightly loaded. Therefore, MPLS traffic engineering is proposed and by taking advantage of MPLS, traffic engineering can route the packets through explicit paths to optimize network resource utilization and traffic performance. MPLS provides a robust quality of service control feature in the internet. MPLS class of service feature can work in accordance with other quality of service architectures for IP networks.

Time Sensitive Networking (TSN) defined in the IEEE 802.1 working group, is an important enabler for industrial Internet of things, specifically industry 4.0. 3GPP release 16 specifications includes the 5G system as a logical TSN bridge, thus promoting the integration of 5G technology with TSN. This combination provides wireless deterministic communication thus ensuring low, bounded delay and near-zero packet loss. In this thesis, we implement a 5G system in- tegration with TSN using a discrete event network simulator (NS-3). Further, we propose a simplified per egress port scheduling algorithm based on IEEE 802.1Q (scheduled traffic standard) running in the Centralized Network Con- troller (CNC). Average packet delay, average jitter, average throughput and the packet loss is measured for comparing the performance difference when our TSN scheduler is used versus when it is not. The designed system is tested by measuring it’s network impact in terms of average delay and packet loss. The 5GS logical bridge behavior is simulated by varying the 5G bridge de- lay dynamically. For every frame transmission in the queue, the processing delay of a particular bridge is varied with pre-defined set of values. Two sets of 5GS bridge delay variations are considered, i.e. between 1-10ms and 5- 10ms respectively. On calculating the network impact, we conclude that the overall impact on the network decreases as the variation range for the delay gets smaller. This proves that higher delay variations have a significant impact whereas smaller delay variations have a negligible impact on the network. For the latter case, the system delay is considerably stable and thus can be used for industrial applications in real-life TSN scenarios. / Tidskritiska nätverk (TSN) definierat i IEEE 802.1-arbetsgruppen, är en vik- tig faktor för det industriella Sakernas Internet, särskilt när det gäller Industri4.0. Specifikationer enligt 3GPP release 16 inkluderar 5G-system som en lo- gisk TSN-brygga, som främjar integrationen av 5G-teknik med TSN. 5G med TSN ger trådlös deterministisk kommunikation som säkerställer låg, begrän- sad fördröjning och nästan noll paketförlust. I denna rapport implementerar vi en 5G-systemintegration med TSN med hjälp av en diskret händelse simu- lator (NS-3). Dessutom föreslår vi en förenklad algoritm för schemaläggning av portar per utgång baserat på IEEE 802.1Q (Scheduled Traffic Standard) som körs i en centraliserad nätverks-controller (CNC). Genomsnittlig paket- fördröjning, genomsnittlig fördröjningsvariation, genomsnittlig genomström- ning och paketförlust mäts för att jämföra prestandaskillnaden när vår TSN- schemaläggare används jämfört med när den inte används. Det utformade sy- stemet testas genom att mäta nätverkets påverkan i termer av genomsnittlig fördröjning och paketförlust. 5GS logiska bryggbeteende simuleras genom att dynamiskt variera 5G-bryggfördröjningen. För varje bildöverföring varieras bryggans bearbetningsfördröjning med en fördefinierad uppsättning värden. Två fördefinierade uppsättningar av 5GS-fördröjningsvariationer beaktas som ligger mellan 1-10ms respektive 5-10ms. När vi beräknar nätverkspåverkan drar vi slutsatsen att den totala effekten på nätverket minskar när variationen i fördröjningen blir mindre. Detta visar att högre fördröjningsvariationer har en signifikant effekt medan mindre fördröjningsvariationer har en försumbar effekt. I det senare fallet är systemfördröjningen betydligt stabilare och kan användas för tillämpningar i verkliga TSN-scenarier.