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Submitted by Cássio da Cruz Nogueira (cassionogueirakk@gmail.com) on 2017-06-06T15:06:30Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_InjecaoPercutaneaEtanol.pdf: 2287319 bytes, checksum: 220052ddc3122284dc746559e11b3ed8 (MD5) / Approved for entry into archive by Edisangela Bastos (edisangela@ufpa.br) on 2017-06-12T13:46:42Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_InjecaoPercutaneaEtanol.pdf: 2287319 bytes, checksum: 220052ddc3122284dc746559e11b3ed8 (MD5) / Made available in DSpace on 2017-06-12T13:46:42Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_InjecaoPercutaneaEtanol.pdf: 2287319 bytes, checksum: 220052ddc3122284dc746559e11b3ed8 (MD5) Previous issue date: 2016-11-24 / Injeção percutânea de etanol (IPE) guiada por ultrassom (US) tem sido sugerida para o tratamento dos nódulos tireoidianos (NT) benignos. Porém, não há um consenso quanto a quantidade padrão de injeção de etanol, número de aplicações e o tempo de reavaliação, de modo a alcançar a redução de volume máximo, com menores efeitos colaterais possíveis. O objetivo do presente estudo foi avaliar a eficácia de um protocolo IPE para tratar NT sólidos e mistos baseado em uma nova meta. Foi realizado um estudo prospectivo para avaliar os resultados do IPE em 52 pacientes com NT benignos sólidos e mistos. Em cada sessão, a dose de etanol foi fixada em 30% do volume nodular. Os pacientes retornavam um mês depois de cada sessão para reavaliação do NT pelo US. O sucesso terapêutico foi estabelecido como a redução ≥ 30% do volume associado ao desaparecimento de sintomas clínicos e uma completa satisfação estética relatada pelo sujeito. Foi realizada uma média de 2,8 ± 1,9 sessões IPE, com um volume médio total de etanol injetado de 9,1 ± 10,3 mL e um tempo de seguimento de 10,0 ± 8,7 meses. Houve redução de pelo menos 50% do volume inicial nodular em 33 pacientes (63,5%). Em 11 pacientes (21,2%) a redução não atingiu 50% (redução média de 31 ± 11%), mas desses, seis relataram resultados clinicos e estéticos satisfatórios e o tratamento foi interrompido. Portanto, nossa taxa de sucesso terapêutico, considerando os pacientes com resolução clinica e estética foi de 75%, não ocorrendo complicações graves. Nosso estudo sugere que o protocolo é eficaz e seguro para o tratamento de NT benignos sólidos e mistos com base nos resultados alcançados. / Percutaneous ethanol injection (PEI) guided by ultrasound (US) has been suggested for thyroid nodules (NT) benign treatment. However, there is no consensus on the standard amount of ethanol injection, number of applications and the re-evaluation time, in order to reach the maximum volume reduction with lower potential side effects. The aim of this study was to evaluate the effectiveness of an IPE protocol to treat solid and mixed NT based on a new goal. A prospective study was conducted to evaluate the results of the IPE in 52 patients with solid and mixed benign NT. In each session the ethanol dose was fixed at 30% of nodular volume. The patients returned a month after each session for NT reassessment by the US. Therapeutic success was established as a reduction ≥ 30% of the volume associated with the disappearance of clinical symptoms and a complete aesthetic satisfaction reported by the subject. It performed an average of 2.8 ± 1.9 PEI sessions with a total average volume of ethanol injected by 9.1 ± 10.3 mL and follow-up of 10.0 ± 8.7 months. A reduction of at least 50% of nodular initial volume in 33 patients (63.5%). In 11 patients (21.2%) reduction did not reach 50% (mean reduction of 31 ± 11%), but these, six individuals reported satisfactory clinical and cosmetic results and treatment was stopped. So, our therapeutic success rate, whereas patients with clinical and aesthetic resolution was 75%. There were no severe complications. Our study suggests that the protocol is effective and safe for the treatment of solid and mixed benign NT based on our established outcome.

Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2017-04-25T15:11:49Z No. of bitstreams: 2 Dissertação - Mariane Brom Sobreiro - 2017.pdf: 16013047 bytes, checksum: 6d41859718e06adc6294f5de038bc631 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2017-04-25T15:12:31Z (GMT) No. of bitstreams: 2 Dissertação - Mariane Brom Sobreiro - 2017.pdf: 16013047 bytes, checksum: 6d41859718e06adc6294f5de038bc631 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2017-04-25T15:12:31Z (GMT). No. of bitstreams: 2 Dissertação - Mariane Brom Sobreiro - 2017.pdf: 16013047 bytes, checksum: 6d41859718e06adc6294f5de038bc631 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017-03-10 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES / Considering the rate of increase in average annual temperature and the seasonality of rainfall in several regions of the country, investigations on the mechanisms of plant’s response to low water availability become relevant. Tabebuia Alliance species - monophyletic clade of the Bignoniaceae family are commonly known as ipe – are distribuited in areas with different soil and climatic conditions. This feature makes them an interesting model to understand mechanisms tolerance’s to abiotic stresses. For each species there were two groups: control group, which had maintained irrigation; low water availability group, which irrigation was stopped and the experiment continued until the subtrate reached 40% of field capacity. The main objective of this work was to identify differentially expressed genes (DEG) in four species - two from the Brazilian savannah (T. aurea and Handroanthus ochraceus) and two from seasonally dry forests (H. impetiginosus and H. serratifolius). Then, RNA was extracted from the plants for sequencing on the Illumina platform with paired-end sequences of 100 base pairs (bp). Sequences were evaluated for quality control and mapped onto the genome of H. impetiginosus to identify DEG using the R software. The DGEs obtained by DESeq2 were subjected to functional enrichment analysis and potential changes in the level of expression of genes encoding enzymes of particular metabolic pathways. In all tools, H. serratifolius species showed the highest number of DGE (4908 noDESeq2), while H. ochraceus had the lowest number of DGE (6 in DESeq2). Functional enrichment analyzes demonstrated that the species presented, individually or collectively, typical responses of low water availability such as decrease of photosynthetic rate, increase of proline and increase of starch degradation. Although species share some responses, the complexity of organisms does not allow them to exhibit identical behaviors. / Considerando-se o aumento crescente da temperatura média anual e a sazonalidade das chuvas em diversas regiões do país, investigações acerca dos mecanismos de resposta vegetais à baixa disponibilidade hídrica tornam-se pertinentes. Espécies da Aliança Tabebuia – clado monofilético da família Bignoniaceae são comumente conhecidas como ipê – possuem uma ampla distribuição, ocupando áreas com diferentes condições edafoclimáticas. Esta característica torna-as um modelo interessante para se entender os mecanismos de tolerância a estresses abióticos. Sob este cenário, o presente trabalho teve como principal objetivo a identificação de genes diferencialmente expressos (GDE) em quatro espécies – das quais duas são de cerrado stricto sensu (T. aurea e Handroanthus ochraceus) e duas de floresta estacional (H. impetiginosus e H. serratifolius). Para cada espécie houve dois grupos experimentais: grupo controle, o qual teve a irrigação mantida; grupo de baixa disponibilidade hídrica, o qual a irrigação foi interrompida e o experimento mantido até que o subtrato atingisse 40% da capacidade de campo. Em seguida, extraiu-se o RNA das plantas para sequencimento em plataforma Illumina com sequências do tipo “paired-end” de 100 pares de base (pb). As sequências foram avaliadas para o controle de qualidade e alinhadas no genoma de H. impetiginosus para identificação de genes diferencialmente expressos (GDEs) com o uso de pacotes do R. Os GDEs obtidos pelo DESeq2 foram submetidos a análise de enriquecimento funcional e potenciais alterações no nível de expressão de genes que codificam enzimas de determinadas vias metabólicas. Em todas as ferramentas, a espécie H. serratifolius apresentou o maior número de GDEs (4908 noDESeq2), enquanto H. ochraceus apresentou o menor número de GDEs (6 no DESeq2). As análises de enriquecimento funcional demonstraram que as espécies apresentaram, individual ou coletivamente, respostas típicas de baixa disponibilidade hídrica como diminuição de taxa fotossintética, aumento de prolina e aumento da degradação de amido. Ainda que as espécies compartilhem algumas respostas, a complexidade dos organismos não permite que exibam comportamentos idênticos.

Combining insights from critical discourse analysis (CDA) and neo-Gramscian IPE theory, this paper puts forth a cultural political economy (CPE) perspective to analyse the discursive articulation of ‘European subjects’ in the context of the EU’s Lisbon Agenda modernisation strategy. It is suggested here that the transformation proposed in Lisbon to the new economic imaginary of the knowledge based economy (KBE), depends on ‘new subjects’ and thus new discursive constructions of identities to reflect the new economic and social formations it envisions. The citizenship discourses of two of the Lisbon Agenda’s main supporters, specifically European business lobbies (represented by the ERT and LCEC) and the EU Commission, are examined in order to explore the relationship between citizenship rights and responsibilities and the two main goals of the Agenda, namely economic competitiveness/growth and social inclusion/social welfare protection modernisation. The argument is made that the discursive articulation of a ‘neoliberal communitarian’ variant of citizenship, especially evident in the discourses of the EU’s business lobbies and the EU Commission since the ‘shift’ to jobs and growth in early 2005, represents an attempt to further the commodification of the EU polity, and as a result, subordinate the more social goals of the Lisbon Agenda to the perceived imperatives of economic growth and competition. The Lisbon Agenda does not therefore mark a dramatic ‘turning point’ in favour of a more ‘social Europe’ as was speculated early on, but instead works to consolidate the dominance of ‘embedded neoliberalism’ as the socio-economic governance model for the EU. The paper ends with a discussion of the possible counter-hegemonic movements challenging the orthodoxy of embedded neoliberalism and neoliberal communitarian conceptions of citizenship.

Per- and polyfluorinated substances (PFAS) are compounds that consist of a carbon chainbackbone that is partially or entirely fluorinated, with an addition of a functional group. SomePFAS are known as persistent organic pollutants (POPs) and have therefore been drawing a lot ofattention as well as increased concerns. PFAS have been detected in humans, wildlife and theenvironment and some have exhibited toxic effects such as hepatotoxicity, immunotoxicity,reproductive toxicity and endocrine disruption as well as being persistent and bioaccumulative.Serum, plasma and whole blood have been used as biomonitoring matrices in many studies toevaluate human exposure to PFAS. Restrictions have been applied to some PFAS, but thesecompounds are still ubiquitous. This study will investigate the performance (recovery, matrixeffect (ME) in terms of intra-/inter-day repeatability) of ion-pair extraction (IPE) and solid phaseextraction with weak anion exchange (SPE-WAX). The extraction methods were adapted fromliterature and 13 PFAS were selected for this work based on prior biomonitoring studies. Thetarget PFAS content was analyzed with liquid chromatography coupled with tandem massspectrometry (LC-MS/MS). The extraction methods were also compared for extractableorganofluorine (EOF) extraction in terms of blank levels as well as the amount extracted withdifferent methods; the EOF content was measured with combustion ion chromatography (CIC).The EOF levels were used to estimate the amount of unidentified organofluorine (UOF), to avoidunderestimating potential health hazards. Samples extracted using IPE had an average ionizationenhancement of 9%, while SPE-WAX showed an average ionization suppression of -1%. SPEWAXshowed higher average recoveries for procedural blanks (78%), horse serum (96%) andhuman serum (95%) in comparison to IPE (69%, 36%, 88%, respectively). The CIC analysis forEOF content was observed to be below MDL (<50 ng/mL F) with some contaminations observedin the procedural blanks.

The master thesis is focused on analysis of stress field in the vicinity of stress concentration of stainless steel IPE beam loaded in tree point bending. Theoretical part includes introduction to fracture mechanics with basic terms, principles and variables used to describe fatigue behaviour of material. It concludes teoretical grounds of fracture tests which are future focus of the thesis, methodes used by numerical softwares and methodes used to obtain numerical results. Practical part includes comparision between two and three dimensional numerical models in three point bending, IPE model with different crack front shapes and plastic zone size. Numerical modelling was processed in Ansys Mechanical APDL. Thesis also involves results of experimental testing evaluated using numerical model.

Made available in DSpace on 2015-03-26T13:53:35Z (GMT). No. of bitstreams: 1 resumo.pdf: 975706 bytes, checksum: b7f729aac6cddff22d4ac5ac02bd1e93 (MD5) Previous issue date: 2008-12-05 / The biome of the Atlantic Forest has sufered a continuous devastation process, with vast ecological and environmental consequences, and the main form of forest restoration is the planting of seedlings. The production of native tree species seedlings of the Atlantic, the hydroeletric plant of Itaipu Binational aims to reforest the riparian vegetation of ltaipu Lake, and constitute the Biological Corridor which will connect Iarge areas of protected forest in Brazil, Paraguay and Argentina. This venture is considered by UNESCO one of the largest environmental conservation projects of the world and includes the Morro do Diabo State Park, in the extreme west of São Paulo, the lguaçu National Park. between Paraná and Mato Grosso do Sul the green bands around the ltaipu power plant reservoir, the lguaçu and the lguazú National Park in Argentina, and the Turvo State Park in the state of Rio Grande do Sul. ln seedling production, the company gardens use a commercial substrate and plastic tubes of 115 cm3 of capacity. The experiments were conducted in the greenhouse of the Soil Department of the Federal University of Viçosa to evaluate the effects of macronutrients doses (N, P, K, Ca, Mg and S) on the growth of Cedrella fissilis Vellozo (Cedro), Peltophorum dubium (Spreng.) Taub (Canafístula) and Tabebuia serratifolia (Vahl) Nichols. (Ipê-amarelo), produced in tubes and substrate. The seedlings after 90 days of emergency received five doses of each macronutrient by cover application. The experimental design used was the completely randomized, with three species, five doses, six nutrients, with five repetitions with four plants each, towling 90 treatments and 1800 plants. After l40 days, for each species it was evaluated the number of leaves, stems, diameter and height of the neck, and determined the total dry weight and subdivided into leaves, stem, aerial part (MSPA), the dry mass relation of the aerial part with the root. We also evaluated the Ievels of N, P, K, Ca, Mg and S in leaves and roots. The increase of N doses províded significant growth for the three evaluated species. The increase of Mg doses significantly influenced the growth characteristics in canafístula plants and Ipê-amarelo. The increase of S doses favored the increments in plant height characteristícs of Ipê-amarelo. For the nutrients that provide significant responses by the regression analysis the recommended doses for maximum production were in the order of 200 mg dm-3 N, 240 mg dm-3 of Mg and 100 mg dm-3 of S. For the zero dose, the N in the maximum applied dose (200 mg dm-3) for plants of Cedro, Ipê-amarelo and Canafístula provided an increase of 6.4, 20.5 and 20.8% in MSPA. Rcspectively, the Mg in the maximum evaluated dose (240 mg dm-3) for seedlings of Ipê-amarelo and Canafístula provided an increment of 7.7 and 8.3% in MSPA, respectively, and S for the ipe scedlings. in the maximum evaluated dose (100 mg dm-3) provided an increase of 5.5% in the MSPA. The critical levels of N in the leaf tissues in Cedro plants, Canafístula and Ipê-amarelo, were 23.07, 20.61 and 22.68 g kg-1, and in the roots 10.83, 9.8 and 14. 19 g kg-1, respectively. The critical Mg levels in lhe leaf tissues in Canafístula and lpê-amareelo plants. were 0.96 and 1.76 g kg-1, and in the roots 0.57 and l.l9 g kg-1, respectively. The critical S levels in lpê-amarelo plants in the leaf tissues. were O.49 g kg-1 and 0.52 g kg-1 in the roots. The other nutrients did not show the recommended doses for the maximum production, justified probably by the presence of these nutrients in the substrate, near or above the critical level. ln general, the response of significant growth with the increase of N availabilíty is possibly Iinked to favorable conditions of leaching in the production of forest species grown in plastic tubes. For the advantage of the balance and availability of nutrients in the commercial substrate used, it is recommended the use of additional fertilization in Mg substrate for Canafístula and Ipê-amarelo, S for the lpê-amarelo and N for the three species. / O bioma da Mata Atlântica tem sofrido um processo contínuo de devastação, com grandes consequências ecológicas e ambientais, e a principal forma de recomposição florestal é o plantio de mudas. A produção de mudas de espécies arbóreas nativas da Mata Atlântica, na Usina Hidrelétrica de Itaipu Binacional tem o objetivo de reflorestar a mata ciliar do lago de Itaipu, e constituir o Corredor Biológico que interligará grandes áreas de mata protegida no Brasil, Paraguai e Argentina. Este empreendimento é considerado pela UNESCO um dos maiores projetos de conservação ambiental do mundo e inclui o Parque Estadual do Morro do Diabo, no extremo oeste de São Paulo; o Parque Nacional de Iguaçu, entre Paraná e Mato Grosso do Sul; as faixas verdes em torno do reservatório da usina de Itaipu; o Parque Nacional do Iguaçu e o de Iguazú, na Argentina; e o Parque Estadual do Turvo, no Rio Grande do Sul. Na produção de mudas, os hortos da empresa utilizam substrato comercial e tubete de 115 cm3 de capacidade. Os experimentos conduzidos em casa de vegetação do Departamento de Solos da Universidade Federal de Viçosa objetivaram avaliar os efeitos de doses dos macronutrientes (N, P, K, Ca, Mg e S). sobre o crescimento de Cedrella fissilis Vellozo (Cedro), Peltophorum dubium (Spreng.) Taub (Canafístula) e Tabebuia serratifolia (Vahl) Níchols. (lpê-amarelo), produzidas em tubete e substrato. As plântulas após aproximadamente 90 dias de emergência receberam cinco doses de cada macronutriente via aplicação em cobertura. O delineamento experimental utilizado foi o inteiramente casualizado, sendo três espécies, cinco doses, seis nutrientes, com cinco repetições com quatro plantas cada, totalizando 90 tratamentos e 1800 plantas. Após 140 dias, foi avaliado para cada espécie o número de folhas, hastes, diâmetro do colo e altura, e determinado a matéria seca total e subdividida em folha, caule, parte aérea (MSPA), de raízes, a relação da massa seca da parte aérea com a raiz. Foram avaliados ainda os teores de N, P, K. Ca. Mg e S nas folhas e raízes. O aumento das doses de N proporcionou o crescimento significativo para as três espécies avaliadas. O aumento das doses de Mg influenciou as características de crescimento significativamente nas plantas de canafístula e Ipê-amarelo. O aumento das doses de S favoreceu os incrementos nas características de crescimento das plantas de Ipê-amarelo, para a produção máxima foram da ordem de 200 mg dm-3 de N, 240 mg dm-3 de Mg e 100 mg de de S. Em relação a dose zero, o N na máxima dose aplicada (200 mg dm-3), para as plantas de Cedro, Canafístula e Ipê-amarelo, proporcionou um incremento de 6,4, 20,5 e 20,8 % na MSPAA respectivamente; 0 Mg na dose máxima avaliada (24O mg dm-3), para as mudas de Canafístula e Ipê-amarelo proporcionou um incremento de 7,7 e 8,3 % na MSPA, respectivamente e o S para as mudas de Ipê-amarelo, na dose máxima avaliada (100 mg dm-3 ), proporcionou um incremento de 5.5 % na MSPA. Os teores críticos de N nos tecidos foliares nas plantas de Cedro, Canafístula e Ipé-amarelo, foram de 23,07, 20,61 e 22,68 g kg-1, e nas raízes 10,83, 9,8 e 14,19 g kg-1, respectivamente. Os teores críticos de Mg nos tecidos foliares nas plantas de Canafístula e Ipê-amarelo, foram de 0.96 e I,76 g kg-1, e nas raízes 0,57 e l,l9 g kg-1, respectivamente. Os teores críticos de S nas plantas de Ipê-amarelo, nos tecidos foliares, foram de 0,49 g kg-1 e 0.52 g kg-1 nas raízes. Os demais nutrientes não apresentaram as doses recomendadas para a produção máxima, justificado, provavelmente pela presença destes nutrientes no substrato, próximo ou acima do nível crítico. Em geral a resposta de crescimento significativo com o aumento da disponibilidade de N, possivelmente está ligada as condições favoráveis de lixiviação na produção de espécies florestais produzidas cm tubetes. Para o favorecimento do equilíbrio e disponibilidade de nutrientes no substrato comercial utilizado, é recomendado o uso de adubação complementar em substrato de Mg, para a Canafístula e Ipê-amarelo, de S para o Ipê-amarelo e de N para as três espécies.

This study was developed in the master s program from Universidade Federal de Uberlândia (UFU) on the field State, Policy and Management Education. It has as goal to analise the (re)definition of the role of the State and the changes of the public management from Minas Gerais (MG) State. Therefore, it was taken as methodology a literature and documental review of the subjects proposed in this study, also an analysis of official government documents. In the study, it is specially analyzed the State and the educational Policies developed during both terms of Aécio Neves as governor of Minas Gerais, the research seeks to understand the assumptions of the implemented reform; the purposes of the management and their instruments through the Choque de Gestão Program. It was focused in the study the process of the implementation of the Individual Performance Evaluation (IPE) of the Education employees from public schools of MG in Uberlândia city, under the logic of the new public management called managerial as an economical, social, political strategy. A qualitative research was developed by applying open questionnaires from the visit to five public schools of Uberlândia city (MG). It is analyzed in a subjective way, among the actors, the prospects of implementing and developing the IPE in the schools and how it has influenced the day-to-day teaching practice of education professionals. / Esta dissertação desenvolvida no curso de Mestrado, na Linha Estado, Política e Gestão da Educação do Programa de Pós-Graduação em Educação da Universidade Federal de Uberlândia (UFU), busca analisar a (re) definição do papel do Estado e as mudanças ocorridas na administração pública estadual mineira. Faz-se uma leitura bibliográfica e documental dos temas propostos e, analisa os documentos oficiais do governo. Analisando de forma especial o Estado e as políticas educacionais desenvolvidas durante as duas gestões do governo Aécio Neves como governador do Estado de Minas Gerais (MG), a pesquisa busca compreender os pressupostos da reforma implantada; as finalidades da gestão e seus instrumentos através do Programa Choque de Gestão. Focalizamos este estudo em torno do processo de implementação da Avaliação de Desempenho Individual (ADI) dos servidores da educação do Estado de Minas Gerais nas escolas da rede estadual mineira da cidade de Uberlândia (MG) sob a lógica da nova administração pública denominada gerencial como uma estratégia política, social e econômica do governo. Desenvolve como mecanismo final, uma pesquisa qualitativa através da aplicação de questionário aberto a partir de visita a cinco escolas da Rede Estadual de Ensino de Uberlândia (MG). Analisa de forma subjetiva, entre os atores, quanto às perspectivas de implementação e desenvolvimento da ADI nas escolas e como ela tem influenciado o dia-a-dia da prática pedagógica dos profissionais da educação. / Mestre em Educação

La collaboration entre les professionnels de la santé s’avère être nécessaire pour faire face au vieillissement de la population, à la prévalence des maladies chroniques et à la pénurie de personnel chez certaines professions de la santé (OMS, 2010). De plus, pour favoriser une collaboration optimale et offrir des soins de qualité, des équipes choisissent désormais d’adopter une approche de soins en partenariat patient où la collaboration interprofessionnelle se déroule en valorisant les savoirs expérientiels du patient à l’égard de la vie avec la maladie et en l’intégrant dans l’équipe de soins. L’Université de Montréal (UdeM) offre une formation à l’éducation à la collaboration interprofessionnelle (EIP) visant à enseigner des compétences de la pratique collaborative en sciences de la santé et en sciences psychosociales en partenariat avec le patient. L’EIP est confrontée à divers défis, entre autres, de logistique, de communication et de cloisonnement des professions. Pour surmonter ces obstacles, l’UdeM s’est donc tournée vers le numérique afin de permettre à des équipes interprofessionnelles d’étudiants de collaborer en ligne et en présentiel. Cette étude s’intéresse donc à décrire comment les étudiants réunis en équipe interprofessionnelle collaborent dans le contexte du cours hybride de Collaboration en sciences de la santé (CSS) en partenariat avec le patient offert par l’UdeM. Nous décrivons comment les étudiants collaborent en ligne et en présentiel et nous identifions les compétences du référentiel de compétences mobilisées. Notre étude propose un cadre conceptuel basé sur l’apprentissage collaboratif en mode hybride (en ligne et en présentiel) de l’EIP composé 1) du modèle de Chiocchio, Grenier, O’Neill, Savaria et Willms (2012) permettant de décrire comment les équipes d’étudiants mobilisent les dimensions de la collaboration (communication, synchronisation, coordination implicite et explicite); 2) du référentiel de compétences de la pratique collaborative et de partenariat patient en santé et services sociaux (Direction collaboration partenariat patient [DCPP] et Comité interfacultaire opérationnel l’Université de Montréal [CIO-UdeM], 2016) et 3) de la typologie du travail interprofessionnel de Xyrichis, Reeves, Zwarenstein (2018). 18 Notre étude emploie une méthodologie mixte convergente. Nous avons mené cette étude auprès d’une cohorte de 1435 étudiants de deuxième année de baccalauréat dans le cadre du cours CSS2900 provenant de treize programmes à l’UdeM. Ce cours se divise en trois volets: 1) formation en ligne 2) activité intraprogramme, 3) atelier interprofessionnel en présentiel coanimé par un professionnel de la santé et un patient formateur. Premièrement, nous avons analysé le Journal de bord collaboratif (JBC) de douze équipes interprofessionnelles d’étudiants (n=60), soit un corpus de cette cohorte. Deuxièmement, nous avons partagé un questionnaire La collaboration en équipes interprofessionnelles à la cohorte à la fin du cours et celui-ci a été répondu par 321 participants. Les résultats indiquent que les participants de l’étude ont majoritairement et similairement mobilisé les dimensions de la collaboration. La communication et la coordination seraient tributaires de la synchronisation lorsque la collaboration se déroule en ligne. L’usage des médias sociaux et d’un outil d’écriture collaborative en ligne auraient favorisé la collaboration en mode hybride. En présentiel, le patient partenaire coanimateur a soutenu des équipes pour faire le point sur leurs apprentissages et ainsi développer des compétences du référentiel du cours CSS2900. Le contexte de l’étude en mode hybride permet aux équipes de collaborer sur une longue période, à la manière d’une classe inversée (figure 29). Ceci favoriserait le développement des compétences du référentiel (DCPP et CIO-UdeM) et le décloisonnement des professions. Les contextes d’apprentissage où les pratiques des compétences effectives ont été mobilisées semblent se rapprocher du réseautage interprofessionnel et de la collaboration consultative de la typologie de Xyrichis et coll. (2018). / Collaboration among health professionals is required to contend with population aging, the prevalence of chronic illnesses, and staff shortages in certain health professions (WHO, 2010). As well, to foster optimal collaboration and provide good quality of care, some teams are now adopting a patient partnership approach in which the patient’s experiential knowledge of living with illness is valued as part of the interprofessional collaboration and the patient is integrated into the healthcare team. The Université de Montréal (UdeM) offers a program in interprofessional collaboration education (IPE) geared towards teaching the competencies required for collaborative practice in both health sciences and psychosocial sciences in partnership with patients. The IPE is confronted with a variety of challenges related to logistics, communication, and the compartmentalization of professions, among others. To overcome these obstacles, the UdeM has turned to digital technology to help interprofessional teams of students to collaborate online and in person. This study focused on describing how students in interprofessional teams collaborate in the hybrid course entitled Health Sciences Collaboration in Partnership with Patients, offered by the UdeM. We describe how students collaborate online and in the classroom, and we identify the competencies in the competency framework used. Our study proposes a conceptual framework based on the IPE’s hybrid (online and in person) collaborative learning model, which we constructed using: 1) the model of Chiocchio, Grenier, O’Neill, Savaria, and Willms (2012), to describe how the student teams collaborate and used dimensions of collaboration (communication, synchronisation, explicit and implicit coordination) ; 2) the competency framework for collaborative practice and patient partnership in health and social services (Direction collaboration et partenariat patient [DCPP] and Comité interfacultaire opérationnel de formation à la collaboration, l’Université de Montréal [CIO-UdeM], 2016); and 3) the interprofessional work typology of Xyrichis, Reeves, and Zwarenstein (2018). Our study used a convergent mixed methodology. We conducted this study with a cohort of 1,435 second-year undergraduate students in course CSS2900 coming from 13 20 different UdeM programs. This course is divided in three parts: 1) online training 2) intra- program activity, 3) interprofessional workshop coanimated by a health professional and patient-partner facilitator in classroom. First, we analyzed the online collaboration journal (OCJ) of 12 interprofessional student teams (n = 60). Second, we distributed a questionnaire on Collaboration in Interprofessional Teams to the entire cohort at the end of the course, to which 321 participants responded. The results show that the majority of study participants used the dimensions of collaboration in a similar manner online and in person. Communication and coordination were dependent on synchronization when collaboration occurred online. The use of both social media and an online collaborative writing tool fostered collaboration in hybrid mode. In the classroom, the patient-partner co-facilitator supported the teams as they reviewed their learning (coordination) and, in this way, developed the competencies of the framework for course CSS2900. Under the hybrid study model, the teams were able to collaborate over an extended period, similar to a flipped classroom approach (Figure 29). This fostered development of the framework competencies (DCPP and CIO-UdeM) and helped break down professional boundaries. The learning contexts in which effective competency practices were mobilized appeared analogous to the interprofessional networking and consultative collaboration categories in the typology of Xyrichis et al. (2018).