Film noir slutar aldrig att fascinera med sin förmåga att kombinera ljus och mörker i en otroligt stiliserad och väl genomarbetad mise-en-scène. Den omisskänneliga mörka stämningen och tonen – den karakteristiska noir-känslan – är konstant närvarande och reflekteras i såväl de typiska noir-karaktärerna som i storyn och i mise-en-scène. Liksom film noir är Tom Fords filmer genomtänkta i minsta detalj och det visuella sätts i fokus. Min uppsats är en stilanalys av den samtida noir-filmen Nocturnal Animals (2016) ur ett neo-noir-perspektiv.         Syftet med denna uppsats är att analysera olika stildrag – mise-en-scène, cinematografi och klippning – samt utmärkande noir-teman. Vilken funktion har de olika stildragen i berättarstrukturen? Hur synliggörs klassiska noir-teman i filmen och hur skiljer sig neo-noir från den klassiska film noir? Genrefrågan debatteras fortfarande och därför används genreteori som en bakgrundsteori. De flesta filmforskare och filmkritiker ser film noir som en stil och inte en genre, eftersom de inte kunnat enas om en gemensam struktur och då film noir anses vara starkt förbunden med en viss tidsperiod och delar för många egenskaper med andra genrer.        Neo-noir bygger på dagens filmskapares medvetenhet om den klassiska noir-filmens stilistiska och narrativa konventioner. Nocturnal Animals innehåller flera noir-teman. Det som skiljer den klassiska film noir från neo-noir är framförallt användningen av färg, och miljöerna och handlingen som tagits till en ny nivå, dvs. brottstemat och våldet har blivit brutalare och visas inte sällan utan upplösning. Neo-noir innehåller också mer skräck och karaktärerna, klippningen och ljussättningen har utvecklats. Både film noir och neo-noir lägger tonvikten på det visuella med en väl genomtänkt mise-en-scène, vilket även är karakteristiskt för Tom Fords filmer. Neo-noir-filmernas uppbyggnad och stil återspeglar den höga graden av medvetenhet om den klassiska noir-filmens stilistiska och narrativa konventioner.

Outdoor artificial light at night (ALAN) is raising concern as a possible cause of the loss of insect diversity. Due to a diurnal bias in standard methods in environmental monitoring and urban ecosystem service assessments, the issue has remained in the dark and especially relevant for nocturnal pollination, which is less well known. This umbrella review analyses the effects of light pollution on pollination services at night through a cascade framework. The report aims to gather understanding of the state of scientific knowledge to date of the combined interdisciplinary field of pollination, ecosystem services and light pollution. Findings show that outdoor lighting works as barriers and habitat fragmentation for nocturnal pollinators reducing flower visitation and pollen transport affecting plant reproduction. Integrating the understanding of stressors of light pollution and the benefits of darkness into urban land use planning have the possibility of improving the abilities of pollination services in a nightscape usually overlooked. Case studies on the benefits of darkness in the management of urban ecosystem services are of interest in future studies together with the mapping on the values of nocturnal pollination networks. / Nattbelysning utomhus har väckt oro som möjlig orsak till förlusten av insektsmångfalden. Det är särskilt relevant för nattliga pollinatörer, som är mindre känt. På grund av en partiskhet till att metoder för miljöövervakning och bedömningar av urbana ekosystemtjänster sker främst på dagen har problemet förblivit skymt i mörkret. Denna paraplygranskning analyserar effekterna av ljusföroreningar på pollineringstjänster på natten genom ett kaskadramverk. Rapporten syftar till att samla förståelsen för det vetenskapliga kunskapsläget inom det kombinerade tvärvetenskapliga området pollinering, ekosystemtjänster och ljusföroreningar. Resultat visar att utomhusbelysning fungerar som barriärer och fragmentering av livsmiljöer för nattaktiva pollinatörer, vilket minskar blombesök och pollentransport och i sin tur växternas reproduktion. Att integrera förståelsen för stressorer av ljusföroreningar och fördelarna med mörker i urban markanvändningsplanering ger möjligheter att stärka förmågan hos pollineringstjänster i ett nattlandskap som annars blivit förbisett. Fallstudier om fördelarna med mörker i förvaltningen av urbana ekosystemtjänster är av intresse i framtida studier tillsammans med kartläggningen av värdena av nattliga pollineringsnätverk.

The dark kangaroo mouse, Microdipodops megacephalus, is a sensitive species in the Great Basin Desert. This thesis explores the structure of desert rodent communities of the Great Basin to better understand M. megacephalus' place in the community and the conditions that promote large and stable populations. To determine community structure, I used nestedness analysis to evaluate 99 communities of nocturnal granivorous rodents. I found that the community structure was non-random, indicating the existence of assembly rules and ecological constraints. I also found that M. megacephalus was the second most vulnerable species in the community. To explore the correlation between species diversity and relative abundance, I performed regression analyses on M. megacephalus and five commonly co-occurring species of the nocturnal granivore guild: Perognathus longimembris (little pocket mouse), Perognathus parvus (Great Basin pocket mouse), Dipodomys ordii (Ord's kangaroo rat), Dipodomys microps (chisel-toothed kangaroo rat), and Peromyscus maniculatus (deer mouse). Results showed a positive correlation between rodent species diversity and relative abundance for M. megacephalus, P. longimembris, P. parvus, and D. microps, and a negative correlation for D. ordii and P. maniculatus. To further understand community composition, I ran interspecific association analyses based on presence-absence data for the six species using chi-square to determine strength of interspecific associations. I found positive interspecific associations between M. megacephalus and P. parvus, between P. longimembris and P. parvus, between P. longimembris and D. microps, and between D. microps and P. maniculatus, and a negative association between P. longimembris and P. maniculatus. A species cluster dendogram with respect to sites in common further supports the interspecific association results. A site cluster dendogram with respect to species abundances implies that dune habitat promotes diversity but not uniformity. All results indicate that M. megacephalus is more abundant and stable at sites with high species richness. The results also provide evidence for the existence of assembly rules, competition, and niche partitioning in desert rodent communities.

Hematopoietic stem cells (HSCs) are critical to the development of the hematopoietic system during ontogeny and maintaining hematopoiesis under steady-state. Several genes implicated in asymmetric cell division (ACD) have been found to influence HSC self-renewal in normal hematopoiesis and various leukemias. From a separate survey of genes associated with ACD, I now present the results from dedicated functional studies on two genes – Arhgef2 and Staufen1 – in HSCs and identify their potential contributions to benign hematopoietic disorders. Specifically, I present evidence that demonstrates a conserved role of Arhgef2 in orienting HSC division, the loss of which leads to HSC exhaustion that may underlie and contribute to the pathogenesis of Shwachman-Diamond syndrome. I also identify Staufen1 as a critical RNA-binding protein (RBP) in HSC function, downregulation of which elicits expression signatures consistent with clinical anemias reminiscent of aplastic anemia and/or paroxysmal nocturnal hemoglobinuria. I end by reviewing how RBPs function in HSCs and discuss future research directions that could further elucidate how bone marrow failure syndromes arise at the stem cell level. / Thesis / Doctor of Philosophy (PhD)

Introduktion: Paroxysmal nokturn hemoglobinuri (PNH) är en kronisk, förvärvad, mycket sällsynt sjukdom som kännetecknas av komplementmedierad intravaskulär hemolys och är potentiellt livshotande. Sjukdomen börjar med en störning hos en hematopoetisk stamcell vilket leder till att patienter med PNH får röda blodceller som är känsliga för aktiverat komplementsystem och membranattackkomplexet (MAC). PNH kan ge symtom som exempelvis anemi, trombos och trötthet. PNH kan behandlas med komplementhämmare som förhindrar komplementaktivering och därmed komplementmedierad intravaskulär hemolys. Den först utvecklade komplementhämmaren eculizumab är en C5-hämmare som kontrollerar intravaskulär hemolys. Många patienter visar dock tecken på extravaskulär hemolys under behandling med eculizumab. Därför utvecklades det en C3-hämmare pegcetacoplan som ska även blockera extravaskulär hemolys. Syfte: Syftet med detta arbete var att studera pegcetacoplans effektivitet i komplementhämmare-naiva patienter och effektivitet i jämförelse med eculizumab vid behandling av PNH. Syftet var även att analysera skillnader i effektivitet mellan pegcetacoplan och eculizumab vid behandling av PNH. Metod: Detta examensarbete var ett litteraturarbete där sex vetenskapliga artiklar inkluderades baserat på inklusions- och exklusionskriterier. Inklusionskriterier var klinisk studie som analyserade pegcetacoplans effektivitet hos patienter med PNH. Exklusionskriterier var bland annat post hoc-analyser och fallrapporter. Artikelsökning gjordes i databasen PubMed med sökorden ”paroxysmal nocturnal hemoglobinuria pegcetacoplan”. Resultat: Pegcetacoplan-behandling ledde till och/eller bibehöll förbättringar gällande bland annat hemoglobinnivåer och LDH-nivåer hos patienter med PNH i alla sex studier. I PHAROAH och PADDOCK/PALOMINO visades en ökning av klonal distribution av typ II och typ III röda blodceller och minskning av C3 på typ II och typ III celler, vilket tolkades som att pegcetacoplan skyddar dessa celler från extravaskulär hemolys. I PRINCE var pegcetacoplan överlägsen kontrollgruppen med stödjande behandling gällande flera utfallsvariabler. I PEGASUS visade både eculizumab och pegcetacoplan effektivitet gällande bland annat LDH-nivåer men pegcetacoplan visade bättre effektivitet än eculizumab gällande hemoglobinnivåer och retikulocytantal. I uppföljningsstudien till PEGASUS och i förlängningsstudien OLE upprätthöll pegcetacoplan de tidigare uppnådda förbättringarna. Diskussion och slutsatser: Resultatet från dessa studier tyder på att pegcetacoplan är ett effektivt läkemedel med ihållande effektivitet vid behandling av PNH gällande kontroll av både intravaskulär och extravaskulär hemolys oavsett tidigare behandling med komplement-hämmare eller inte. Blockering av extravaskulär hemolys var den viktigaste skillnaden i effektivitet mellan pegcetacoplan och eculizumab. Dock skulle trovärdigheten av dessa slutsatser kunna förstärkas om det gjordes fler studier utan påverkan av Apellis Pharmaceuticals. / Introduction: Paroxysmal nocturnal hemoglobinuria (PNH) is a chronic, acquired, rare disease characterized by complement-mediated intravascular hemolysis and is potentially life-threatening. The disease begins with a disorder of a hematopoietic stem cell, which results in patients with PNH having red blood cells that are sensitive to complement activation and the membrane attack complex (MAC). PNH can cause symptoms such as anemia, thrombosis and fatigue. PNH can be treated with complement inhibitors that prevent complement activation and thereby complement-mediated intravascular hemolysis. The first complement inhibitor developed, eculizumab, is a C5 inhibitor that controls intravascular hemolysis. However, many patients show signs of extravascular hemolysis during treatment with eculizumab. Therefore, a C3 inhibitor pegcetacoplan was developed that should also block extravascular hemolysis. Aim: The aim of this study was to evaluate the efficacy of pegcetacoplan in complement inhibitor-naïve patients and efficacy in comparison with eculizumab in the treatment of PNH. The aim was also to analyze differences in effectiveness between pegcetacoplan and eculizumab in the treatment of PNH. Method: This thesis was a literature review in which six scientific articles were analyzed. Inclusion criteria were clinical trial analyzing the efficacy of pegcetacoplan in patients with PNH. Exclusion criteria included post hoc analyzes and case reports. An article search was made in the PubMed database with the keywords "paroxysmal nocturnal hemoglobinuria pegcetacoplan". Results: Pegcetacoplan treatment led to and/or maintained improvements in, among other things, hemoglobin levels and LDH levels in patients with PNH in all six studies. In the PHAROAH and PADDOCK/PALOMINO studies, an increase in the clonal distribution of type II and type III red blood cells and a decrease in C3 on type II and type III cells were shown, which was interpreted as pegcetacoplan protecting these cells from extravascular hemolysis. In PRINCE, pegcetacoplan was superior to the supportive care control group on several outcome variables. In PEGASUS, both eculizumab and pegcetacoplan showed efficacy regarding, among other things, LDH levels, but pegcetacoplan showed higher efficacy than eculizumab regarding hemoglobin levels and reticulocyte count. In the follow-up study to PEGASUS and in the extension study OLE, pegcetacoplan maintained the previously achieved improvements. Discussion and conclusions: The results from these studies suggest that pegcetacoplan is an effective drug with sustained efficacy in the treatment of PNH regarding the control of both intravascular and extravascular hemolysis regardless of previous treatment with complement inhibitors or not. Blockade of extravascular hemolysis was the main difference in efficacy between pegcetacoplan and eculizumab. However, the credibility of these conclusions could be strengthened if more studies were conducted without the influence of Apellis Pharmaceuticals.

Cette thèse de sociologie porte sur les pratiques de sommeil des couples vieillissants confrontés à une maladie neurodégénérative. Elle se fixe comme objectif de saisir les dynamiques temporelles et spatiales de ces pratiques de sommeil, centrales dans la vie du couple, au fil de l'évolution de la maladie en accordant une attention particulière aux relations de genre. Nous avons interviewé 30 couples à domicile, dont 12 concernés par la maladie à corps de Lewy et 18 par la maladie d'Alzheimer et nous avons intégré des dispositifs d'enquête tels que la rédaction de journaux de sommeil, de journaux audio et la constitution d'un ensemble de documentation photographique. L'analyse se déploie selon trois axes. Le premier axe consiste à analyser le rôle du veilleur de nuit assumé par le conjoint aidant. Nous avons constaté le passage du statut de conjoint dormant à celui de "conjoint veilleur". Le rôle de conjoint veilleur est caractérisé par la production d'un travail domestique de soin qui se déroule la nuit et que nous avons appelé "travail domestique nocturne de soin". Nos résultats montrent que ce travail domestique nocturne peut amener le conjoint veilleur à un état d'épuisement qui peut pousser au choix d'institutionnaliser son conjoint malade. Ce travail domestique s'articule avec un état d'inquiétude nocturne du conjoint veilleur qui engendre un sommeil spécifique que l'on peut qualifier de "sommeil en état d'alerte". Il est aussi doublement invisible : il est constitué par des activités se déroulant la nuit et il repose souvent sur les femmes. Le deuxième axe consiste à analyser l'impact de la maladie et des troubles cognitifs sur l'organisation des espaces liés au sommeil en mettant en lumière les négociations qui se font autour de la chambre conjugale. Nous avons dégagé les raisons pour lesquelles une partie des conjoints reste attachée au fait de dormir ensemble. Nous avons aussi analysé les dimensions corporelles liées au partage du lit, contexte où la relation entre les corps trouve son expression privilégiée. Nous avons exploré les expériences de distanciation des conjoints : les significations et les pratiques autour du choix de dormir en couple mais séparés, de faire chambre à part. Le dernier axe porte sur l'analyse des stratégies hétérogènes de la gestion du sommeil telles que l'utilisation des médicaments pour dormir, le recours à la garde nocturne en institution ou au domicile et, enfin, le sommeil diurne. Nous avons analysé les raisons de l'adhésion ou du refus de la part des conjoints aidants et nous avons constaté que la vulnérabilité qui caractérise la nuit et le sommeil peut rendre difficile le recours aux stratégies de gestion du sommeil. / This doctoral dissertation in sociology examines the sleep practices of ageing couples confronted with neuro-degenerative conditions. It aims to understand the time- and space-related aspects of these sleep practices, so central to couples’ lives, throughout the different stages of illness, and places particular emphasis on gender-based relations. Thirty couples were interviewed in their homes, 12 of whom were affected by Lewy Body Dementia and 18 by Alzheimer’s Disease. Empirical methods such as sleep journals, audio journals, and photographic documentation were incorporated into the study’s methodology. The study is divided into three branches. The first branch examines the role of “night-time guardian” assumed by the caregiving partner. The author was able to observe that a shift takes place from the status of sleeping partner to that of night-time caregiver. The role of the “night-time guardian” is characterized by domestic labor that takes the form of caregiving provided at night, a phenomenon the author calls “nocturnal domestic caregiving work”. The findings of the study show that this domestic night-time work can bring about a state of exhaustion in caregiving partners that can drive them to institutionalize the partner suffering from a medical condition. In addition to this domestic work, caregiving partners are prone to a state of night-time worry that results in a specific variety of sleep that can be described as “alert sleep”. This domestic work also goes largely unseen for two reasons: it is made up of activities that take place at night, and it often falls to women. The study's second branch offers an analysis of the impact of illness and cognitive disorders on the way areas of the home associated with sleep are organized, bringing to light the give-and-take that occurs where the marital bedroom is concerned. The author examined the reasons some sleep partners continue to insist on sleeping together. Also addressed are the bodily aspects of shared beds, a special context in which the bonds shared between bodies can be expressed in a unique way. The dissertation further explores the experience of placing distance between sleep partners: the meanings and practices surrounding the decision to sleep as a couple but in separate rooms. The final branch of the study examines a range of strategies used to manage sleep, such as taking sleeping medication, turning to in-home or institutional night-time caretaking, and day-time sleep. The author surveyed the reasons that caregiving partners accepted or refused to utilize these strategies, and the study’s findings show that the vulnerability represented by night and sleep can render it difficult to decide to use strategies to manage sleep.

This 11-month study examined rates of encountering dung pellet groups, dung piles and ungulates in gallery forests and non-gallery forests during diurnal surveys in the Loma Mountains Non-Hunting Forest Reserve (LMNHFR) in Sierra Leone, West Africa. These indices of relative abundance were then used to infer relative habitat use by the seven ungulate species on which data were collected. This study also examined the differences in rates of encountering duikers during nocturnal surveys with rates of encountering duikers during diurnal surveys to determine which time of day produces higher rates of encounter, and thereby a more accurate estimate of duiker abundance. The dung of four of the seven species, namely Cephalophus niger, Philantomba maxwelli, Tragelaphus scriptus, and Potamochoerus porcus is encountered at a higher rate in gallery forest than in non-gallery forest. Rates of encountering the dung of three species, C. silvicultor, C. dorsalis and Syncerus caffer nanus, do not differ between forest types. Rates of encountering four species, namely C. niger, P. maxwelli, T. scriptus, and C. silvicultor are higher in gallery forest than in non-gallery forest. Rates of encountering three species, namely C. dorsalis, S. caffer nanus, and P. porcus do not differ between forest types. Rates of encountering duikers ranged from three to six times higher during nocturnal surveys than during diurnal surveys for C. niger and P. maxwelli and 20 times higher for C. dorsalis. Survey timing did not affect the rate of encounter for C. silvicultor. Forest ungulates in the LMNHFR utilize gallery forests regularly. Possible reasons for the higher rates of encounter for six of the species in gallery forests compared with non-gallery forests are access to water, readily available browse resulting from annual fire damage on the periphery and interior of gallery forests, and easy access to cover for ungulates when foraging in adjacent grassland. Given the current rate of forest loss in West Africa, studies examining how forest mammals are able to persist in small forest fragments should be high priority for both government and conservation groups. The findings here give evidence that forest ungulates can and do use small areas of forest. Most importantly, the findings from this study show the global value of the LMNHFR for the conservation of large mammals endemic to the Upper Guinea Forests.

Very little is known about the spatio-temporal ecology of the rusty-spotted genet, Genetta maculata. With this study I aimed to describe the activity patterns, resting site use and spatial ecology of G. maculata in Telperion Nature Reserve. I particularly looked at the activity profile and the activity period. I wanted to determine the spatial distribution of resting sites, the number of sites used per individual as well as the index of resting site reuse. I also calculated the distance between resting sites on consecutive days and tested for differences between sexes and seasons. I determined the size of home ranges, as well as that of core areas and compared space use between sexes and seasons as well as vegetation types. A total of six males and nine females were trapped, radio-collared and tracked during continuous night and daytime sessions between September 2015 and August 2016. Rusty-spotted genets were primarily nocturnal (nocturnality index: 0.84) and therefore made use of the darkness for cover when hunting. Overall, male effective activity duration (586 ± 172 min) was greater than for females (564 ± 175 min) possibly because they search for females to mate with as well as due to their larger body size. Seasonal changes in activity were evident – specifically in winter – and were probably a function of both food availability and temperature. Areas with a denser vegetation structure seemed to be more suitable for rusty-spotted genet resting sites. Neither the number of resting sites nor the reuse rate of these resting sites differed between sexes or seasons. The inter-resting site distance on consecutive days was higher for males (938 ± 848 m) than females (707 ± 661 m). This was possibly caused by males travelling larger distances when searching for females to mate with. The inter-resting site distance was higher during autumn, likely due to the decrease in food availability, which made it necessary for genets to increase their hunting efforts. However, a similar increase in hunting effort was not evident during winter as genets decreased their overall activity, possibly in order to avoid colder temperatures. No sexual or seasonal differences in home range size were found. This was attributed to a well-spread and consistent availability of food sources. Core areas only covered on average 7% of the total individual home range which further supports the hypothesis that food was readily available. Both intra- and intersexual home range overlaps were recorded. This was not unusual for carnivores and due to a combination of reproductive and social actions. Home ranges mainly included bushveld vegetation (78%) rather than grassland as these areas provided better cover and likely more abundant food sources. As this was the first exhaustive study of its kind on this species over a full annual cycle, the information gathered is important for the development of conservation strategies for this species, but also for other Genetta species in the rest of Africa. / College of Agriculture and Environmental Sciences / M. Sc. (Environmental Science)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / This study investigates the imaginary in Metal rosicler by Cecilia Meireles, one of her last books which was published in 1960. The aim is to analyze the relation of this book and the structures of alchemy imaginary. As well as the spiritual alchemists searched for the transmutation of insignificant metal in order to make it possible for men to reach the enlightenment, in Metal rosicler there is the attempt to go through an ontological search by linking the poetic to the alchemy symbolism, then as it happens in the alchemy process, it reveals itself in the rosicler (the color of a rose). Started by poetry, the search indicates the transmutation of the black stone- the raw rosicler metal- revealing from the depth a hidden and sublime essence in alchemy rosicler. Such essence is the meaningful reason for the search because it represents the desirable entirety in coincidentia oppositorum, and also the integration of the opposites of androgeny. Thus, the transformation may only be completed by performing the phases and the steps in the alchemy ritual: mortification in the nigredo, the abstract ideality in the albedo leading to the whole life of red color in the rubedo. All the symbolism untwines itself before the mitocriticism of poems which is based on contributions of critique about imaginary and alchemy, such as: the imaginary anthropology, according to Gilbert Durant`s work; phenomenology of poetic, as stated by Carl Gustav Jung studies. The theoretical instrument purposed by Durand e Bachelard concerns the imagination s dynamic creation and the strength of myths in peoples representative productions throughout the years. Imaginary philosophy of alchemy is based on Jung s deep psychology perspective which considers the relation between the alchemy symbolism and the process of individualization of human being in the search of entirety of himself. Mitocriticism work reveals the constellation of images which is a response for the alchemy poetic of the book, how the symbols imbricate the imperishable into ephemeral; the nocturnal images which join life and death; images of the air, the water, and the land which brings in the transcendence; dissolution in the nigredo and molding the androgynous, besides the mithemes of Hermes-Mercury in the alchemy become, the symbols of mortification of black stone and the sublimination of rosicler in the rubedo. Therefore, such journey reveals, in poems, the poetic melting pot of transmutation where the lyrical itself searches the spiritual entirety in the extraction of rosicler. / Este estudo explora o imaginário de Cecília Meireles em Metal rosicler, sua penúltima publicação em vida, no ano de 1960. O objetivo é investigar o liame da obra com as estruturas do imaginário alquímico. Assim como os alquimistas espirituais buscavam a transmutação dos metais vis para que o homem alcançasse a iluminação, em Metal rosicler, o eu-lírico empreende uma busca ontológica, entrelaçando o poético ao simbolismo alquímico, a fim de obter, tal como no processo da alquimia, o desvelamento do si mesmo, que se daria no rosicler. Encetada pela poesia, essa busca emblematiza a transmutação da pedra negra o metal rosicler bruto desentranhando, ao final, a essência oculta e sublimada do rosicler. Tal essência fundamenta o sentido da busca, pois ela representa a desejada totalidade na coincidentia oppositorum, ou, ainda, a integração dos opostos na androginia. Nesse sentido, para efetivar a transformação cumprem-se as etapas do ritual alquímico: a mortificação na nigredo, a idealidade abstrata na albedo culminando na vida plena do vermelho na rubedo. Todo esse simbolismo desenreda-se mediante a mitocrítica dos poemas que se funda nos aportes da crítica do imaginário e da alquimia, quais sejam: a antropologia do imaginário, segundo os trabalhos de Gilbert Durand; a fenomenologia do poético, consoante as pesquisas de Gaston Bachelard, e a filosofia da alquimia, conforme os apontamentos de Carl Gustav Jung. O instrumental teórico proposto por Durand e Bachelard referenda o dinamismo criador da imaginação e a força diretiva dos mitos nas produções representativas da cultura de todos os tempos. Por sua vez, a filosofia imaginária da alquimia apóia-se na psicologia profunda de Jung que relaciona o simbolismo alquímico ao processo de individuação do ser em busca da totalidade no si mesmo. No pormenor, o trabalho mitocrítico revela uma constelação de imagens que responde pela poética alquímica do livro, como os símbolos que imbricam o imperecível no efêmero; as imagens noturnas que articulam a vida e a morte; as imagens do ar, da água e da terra que instalam a transcendência, a dissolução na nigredo e a modelagem do andrógino; além dos mitemas de Hermes-Mercúrio no devir alquímico, os símbolos da mortificação da pedra negra e da sublimação do rosicler na rubedo. Assim sendo, tal jornada desvela, no espaço dos poemas, o cadinho poético da transmutação onde o eulírico busca sua inteireza de espírito na extração do rosicler. / Mestre em Teoria Literária

La biodiversité est actuellement fortement menacée par les activités humaines. Dépendant des milieux marins et terrestres, les oiseaux marins sont particulièrement exposés aux pressions anthropiques. À La Réunion, les conséquences des impacts des aménagements sur les populations restent méconnues. Dans une optique de conservation et de réalisation d'études environnementales pertinentes, des informations fiables sur la répartition des espèces, sur leur comportement de vol et une évaluation de leur vulnérabilité vis-à-vis des aménagements sont nécessaires. Les objectifs de cette thèse sont de préciser des données biologiques et d'évaluer la vulnérabilité des oiseaux marins nocturnes de La Réunion face aux aménagements. Nous avons étudié l'évolution de la taille et de la répartition des colonies de puffin tropical Puffinus bailloni à l'échelle de l'île sur une période de 19 ans. Les patterns de vol du puffin tropical et du pétrel de Barau Pterodroma baraui ont été caractérisés par imagerie radar à différentes échelles temporelles et spatiales. Nos résultats montrent une stabilité apparente de la population de puffin tropical malgré la forte pollution lumineuse. Le puffin tropical et le pétrel de Barau présentent des patterns de vol spécifiques. Les effectifs estimés de pétrel de Barau suggèrent une population plus importante que celle connue actuellement. Les effectifs estimés de puffin tropical sont cohérents avec les estimations actuelles. Les jeunes pétrels de Barau s'envolent principalement durant les premières heures de la nuit. Des outils d'aide à la décision ont été produits. Nos travaux soulèvent la nécessité de poursuivre des recherches fondamentales et appliquées. / The biodiversity is currently threatened by human activities. As they depend both of marine and terrestrial habitats, seabirds are particularly exposed to human pressures. In Reunion Island, the consequences of the urbanization on populations are unknown. For conservation and environmental assessment purposes, accurate information on the species repartition, flight patterns and vulnerability to infrastructure is required. The goals of this thesis are to update biological information on species and to assess the vulnerability of nocturnal seabirds of Reunion Island exposed to infrastructure. We studied the evolution of the size and the repartition of the colonies of tropical shearwater Puffinus bailloni at the scale of the entire island over a 19-years period. The flight patterns of tropical shearwater and Barau's petrel Pterodroma baraui were described with radar technology at different spatial and temporal scales. Our results show an apparent stability of the tropical shearwater population despite an important light pollution. Tropical shearwater and Barau’s petrel present specific flight patterns. The estimated census of Barau's petrel suggests a population size higher than current estimation whereas the estimated census of tropical shearwater is reliable to current estimations. Barau's petrels' juveniles mostly take off during the first hours of the night. Decision making tools have been produced. Our study also highlights the need to conduct further fundamental and applied researches.