This essay investigated which professional group within the school is estimated to have the highest degree of theoretical knowledge and competence to intervene in mental illness among students. The study has also looked at which organizational conditions are important for identification and intervention and whether school staff believe that something is missing toachieve this. The study was done through a web survey and was answered by teachers and counselors working in elementary school. The survey contained open questions where the respondents' possible lack of routines and guidelines and support were requested. The central theoretical view was systems theory, which were used to interpret the material. The materialwas analyzed using cross-tabulations, t-tests and linear regression analyses. The results showed that more than double the number of counselors than teachers have further training inmental illness. Within theoretical knowledge, competence to intervene, routines and guidelines and support, counselors rate themselves higher than teachers. Teachers rate themselves lowest regarding theoretical knowledge and counselors answered “perceived support”. Both groups rate routines and guidelines the highest, but they also respond that it´s lacking. The result shows significant differences between the groups regarding theoretical knowledge and competence to intervene. Further education has a positive impact on perceived theoretical knowledge and competence to intervene. Transboundary work and a "whole school approach" are important for school social work, which will also be important to examine in further research. / Denna uppsats undersökte vilken yrkesgrupp inom skolan som skattar sig ha högst grad av teoretisk kunskap och kompetens att intervenera vid psykisk ohälsa bland elever. Studien har även sett till vilka organisatoriska förutsättningar som är viktiga vid identifiering och intervenering samt om skolpersonal anser att det saknas någonting för att uppnå detta. Studien genomfördes genom en webbenkät och besvarades av lärare yrkesverksamma inom årskurs F6 samt skolkuratorer yrkesverksamma inom årskurserna F-9. Enkäten innehöll öppna frågor där respondenternas eventuella avsaknad gällande rutiner och riktlinjer samt stöd efterfrågades. Den centrala teoretiska utgångspunkten var systemteori vilket användes för tolkning av materialet. Det insamlade materialet analyserades med hjälp av korstabeller, t-test och linjära regressionsanalyser. Resultatet visade att mer än dubbla antalet skolkuratorer än lärare har vidareutbildning kring psykisk ohälsa. Inom teoretisk kunskap, kompetens att intervenera, rutiner och riktlinjer samt stöd skattade sig skolkuratorerna högre än lärarna. Lärarna skattade sig lägst kring teoretisk kunskap och skolkuratorerna skattade sig lägst kring upplevt stöd på arbetsplatsen. Båda yrkesgrupperna skattade sig högst kring rutiner och riktlinjer men de svarade även att tydliga rutiner och riktlinjer saknas. Resultatet visade signifikanta skillnader mellan yrkeskategorierna avseende teoretisk kunskap samt kompetens att intervenera. Vidareutbildning har en positiv påverkan på den upplevda teoretiska kunskapen och kompetensen att intervenera. Ett professionsöverskridande arbete och ”whole school approach”är viktigt för det skolsociala arbetet vilket även blir viktigt att undersökas i vidare forskning.

Experimental data suggest that the universe is homogeneous and isotropic on sufficiently large scales. An exact solution of the Einstein field equations exists for a homogeneous and isotropic universe, also known as a Friedmann-Lemaître-Robertson-Walker (FLRW) universe. However, this model is only a first approximation since we know that, locally, the universe has anisotropic and inhomogeneous structures such as galaxies and clusters of galaxies. In order to successfully introduce inhomogeneities and anisotropies to the model one uses perturbative methods. In cosmological perturbations the FLRW universe is considered the zeroth order term in a perturbation expansion and perturbation theory is used to derive higher order terms which one tries to match with observations. In this thesis I present a review of the main concepts of general relativity, discuss the 3+1 formalism which gives us the Einstein field equations in a useful form for the perturbative analysis, and lastly, I derive the first order scalar perturbations of the Einstein field equations.

<p>Uppsatsen presenterar hur högskolestudenter och gymnasieelever av båda könen (killar respektive tjejer) hanterar informationssökning och källkritik på Internet i samband med studier. Syftet med studien är att se skillnader och likheter i tre sökaspekter (informationsbehov, sökstrategi och källkritik). Sedan vill jag se hur tre sökaspekter används av båda könen bland högskolestudenter och gymnasieelever. Undersökningen är en både kvantitativ och kvalitativ studie. Det kvantitativa inslaget bygger på enkätfrågor och öppna frågor medan det kvalitativa inkluderar intervjufrågor. Teoretisk referensram består av litteratur och vetenskapliga artiklar som ger teoretiskt stöd åt ett operationaliseringsschema och ger grund åt hela studien. Studien begränsas till högskolestudenter och gymnasieelever av båda könen som går medieinriktade studier, oberoende av årskursnivå. Ett oväntat resultat som studien visade är, att både högskolestudenter och gymnasieelever av båda könen tittar mest på sina träffar ”Till mitten pålistan”. I studien upptäcktes att högskolestudenter och gymnasieelever av båda könen har kunskap om källkritik, men det stora problemet hos båda grupperna är ”Tidsbrist” och ”Har inte lust”, så att de undviker granska källor på Internet. Högskolestudenter och gymnasieelever av båda könen är medvetna om konsekvenserna som kan uppstå om de inte kritisk granskar källor på Internet. Det sökmönster som högskolestudenter och gymnasieelever av båda könen använder är att de först söker med bred sökning och sedan med smal sökning. Deras val av sökverktyg är ”Google” och de söker mest med sökord.</p>

<p>String theory is a unified framework for general relativity and quantum mechanics, thus being a theory of quantum gravity. In this thesis we discuss various aspects of quantum gravity for particular systems, having in common the existence of horizons. The main motivation is that one major challenge in theoretical physics today is in trying to understanding how time dependent backgrounds, with its resulting horizons and space-like singularities, should be described in a controlled way. One such system of particular importance is our own universe.</p><p>We begin by discussing the information puzzle in de Sitter space and consequences thereof. A typical time-scale is encountered, which we interpreted as setting the thermalization time for the system. Then the question of closed time-like curves is discussed in the combined setting where we have a rotating black hole in a Gödel-like universe. This gives a unified picture of what previously was considered as independent systems. The last three projects concerns $c=1$ matrix models and their applications. First in relation to the RR-charged two dimensional type 0A black hole. We calculate the ground state energy on both sides of the duality and find a perfect agreement. Finally, we relate the 0A model at self-dual radius to the topological string on the conifold. We find that an intriguing factorization of the theory previously observed for the topological string is also present in the 0A matrix model.</p>

<p>The ability to accurately predict binding free energies from computer simulations is an invaluable resource in understanding biochemical processes and drug action. Several methods based on microscopic molecular dynamics simulations exist, and in this thesis the validation, application, and development of the linear interaction energy (LIE) method is presented.</p><p>For a test case of several hydrophobic ligands binding to P450cam it is found that the LIE parameters do not change when simulations are performed with three different force fields. The nonpolar contribution to binding of these ligands is best reproduced with a constant offset and a previously determined scaling of the van der Waals interactions.</p><p>A new methodology for prediction of binding free energies of protein-protein complexes is investigated and found to give excellent agreement with experimental results. In order to reproduce the nonpolar contribution to binding, a different scaling of the van der Waals interactions is neccesary (compared to small ligand binding) and found to be, in part, due to an electrostatic preorganization effect not present when binding small ligands.</p><p>A new treatment of the electrostatic contribution to binding is also proposed. In this new scheme, the chemical makeup of the ligand determines the scaling of the electrostatic ligand interaction energies. These scaling factors are calibrated using the electrostatic contribution to hydration free energies and proposed to be applicable to ligand binding.</p><p>The issue of codon-anticodon recognition on the ribosome is adressed using LIE. The calculated binding free energies are in excellent agreement with experimental results, and further predict that the Leu2 anticodon stem loop is about 10 times more stable than the Ser stem loop in complex with a ribosome loaded with the Phe UUU codon. The simulations also support the previously suggested roles of A1492, A1493, and G530 in the codon-anticodon recognition process.</p>

String theory is a unified framework for general relativity and quantum mechanics, thus being a theory of quantum gravity. In this thesis we discuss various aspects of quantum gravity for particular systems, having in common the existence of horizons. The main motivation is that one major challenge in theoretical physics today is in trying to understanding how time dependent backgrounds, with its resulting horizons and space-like singularities, should be described in a controlled way. One such system of particular importance is our own universe. We begin by discussing the information puzzle in de Sitter space and consequences thereof. A typical time-scale is encountered, which we interpreted as setting the thermalization time for the system. Then the question of closed time-like curves is discussed in the combined setting where we have a rotating black hole in a Gödel-like universe. This gives a unified picture of what previously was considered as independent systems. The last three projects concerns $c=1$ matrix models and their applications. First in relation to the RR-charged two dimensional type 0A black hole. We calculate the ground state energy on both sides of the duality and find a perfect agreement. Finally, we relate the 0A model at self-dual radius to the topological string on the conifold. We find that an intriguing factorization of the theory previously observed for the topological string is also present in the 0A matrix model.

The ability to accurately predict binding free energies from computer simulations is an invaluable resource in understanding biochemical processes and drug action. Several methods based on microscopic molecular dynamics simulations exist, and in this thesis the validation, application, and development of the linear interaction energy (LIE) method is presented. For a test case of several hydrophobic ligands binding to P450cam it is found that the LIE parameters do not change when simulations are performed with three different force fields. The nonpolar contribution to binding of these ligands is best reproduced with a constant offset and a previously determined scaling of the van der Waals interactions. A new methodology for prediction of binding free energies of protein-protein complexes is investigated and found to give excellent agreement with experimental results. In order to reproduce the nonpolar contribution to binding, a different scaling of the van der Waals interactions is neccesary (compared to small ligand binding) and found to be, in part, due to an electrostatic preorganization effect not present when binding small ligands. A new treatment of the electrostatic contribution to binding is also proposed. In this new scheme, the chemical makeup of the ligand determines the scaling of the electrostatic ligand interaction energies. These scaling factors are calibrated using the electrostatic contribution to hydration free energies and proposed to be applicable to ligand binding. The issue of codon-anticodon recognition on the ribosome is adressed using LIE. The calculated binding free energies are in excellent agreement with experimental results, and further predict that the Leu2 anticodon stem loop is about 10 times more stable than the Ser stem loop in complex with a ribosome loaded with the Phe UUU codon. The simulations also support the previously suggested roles of A1492, A1493, and G530 in the codon-anticodon recognition process.

This thesis concerns methods of reduced complexity for electronic structure calculations.  When quantum chemistry methods are applied to large systems, it is important to optimally use computer resources and only store data and perform operations that contribute to the overall accuracy. At the same time, precarious approximations could jeopardize the reliability of the whole calculation.  In this thesis, the self-consistent field method is seen as a sequence of rotations of the occupied subspace. Errors coming from computational approximations are characterized as erroneous rotations of this subspace. This viewpoint is optimal in the sense that the occupied subspace uniquely defines the electron density. Errors should be measured by their impact on the overall accuracy instead of by their constituent parts. With this point of view, a mathematical framework for control of errors in Hartree-Fock/Kohn-Sham calculations is proposed.  A unifying framework is of particular importance when computational approximations are introduced to efficiently handle large systems. An important operation in Hartree-Fock/Kohn-Sham calculations is the calculation of the density matrix for a given Fock/Kohn-Sham matrix. In this thesis, density matrix purification is used to compute the density matrix with time and memory usage increasing only linearly with system size. The forward error of purification is analyzed and schemes to control the forward error are proposed. The presented purification methods are coupled with effective methods to compute interior eigenvalues of the Fock/Kohn-Sham matrix also proposed in this thesis.New methods for inverse factorizations of Hermitian positive definite matrices that can be used for congruence transformations of the Fock/Kohn-Sham and density matrices are suggested as well. Most of the methods above have been implemented in the Ergo quantum chemistry program. This program uses a hierarchic sparse matrix library, also presented in this thesis, which is parallelized for shared memory computer architectures. It is demonstrated that the Ergo program is able to perform linear scaling Hartree-Fock calculations. / QC 20100908

Den internasjonale Safe-Community (SC) bevegelsen vokser stadig. Denne studien setter søkelyset på de såkalte Affiliate Safe Community Support Centres (ASC) og deres rolle i bevegelsen. SC-begrepet blir behandlet både som en innovasjon og som en organisasjons- modell som utbres etter Rogers og Røviks teorier. ASCene ses på som ”forandrings-agenturer” i følge disse teoriene. Studien er en case-study i følge Yin, og dekker 9 av ialt 15 ASCer. Tre av dem har mistet sin status som ASC, seks av dem har sin status i behold. De følgende fem påstander blir studert: 1)Det er ingen forskjell i hvordan sentrene har utøvet sin rolle som årsak til at noen mister sin status og andre ikke. 2)Årsakene til at noen mister sin status ligger i interne organisasjonsmessige, personalmessige eller økonomiske forhold. 3) ASC’ene og deres oppgaver er ikke særlig godt kjent blant ”brukerne” 4)ASC’ene har et svakt eller lite bevisst forhold til det teoretiske og vitenskapelige grunnlag for spredningsprosesser 5)SC-begrepet oppfattes i liten grad som en organisasjonsmodell på linje med andre organisasjonsmodeller. Data ble samlet inn fra spørreskjemaundersøkelser, skriftlig materiale og intervju. Materialet omfatter alle ”nivåer” i SC-bevegelsen. Alle fem påstander ble styrket av materialet. Studien har ledet til følgende konklusjoner og anbefalinger som forhåpentligvis kan styrke både renommé og effektivitet i SC-bevegelsen og lette arbeidet i ASCene: Organisasjonsteori og organisasjonsspørsmål må i langt større grad settes på dagsorden i bevegelsen. Vekst og utbredelse av SC-”ideén” får for stor plass i forhold til konsolidering. Det forekommer konflikter mellom ASC-arbeidet og andre arbeidsoppgaver. Det gjelder særlig når det gjelder prioriteringen mellom forsking og arbeidet med å utbre SC-modellen. ASCene har ikke tilstrekkelig kapasitet til å følge opp veksten i SC-bevegelsen. Begge disse forhold synes hovedsakelig å bunne i mangel på finansiering og mangel på planmessig utbygging. Mangel på planmessig organisering av bevegelsen er foruroligende. Dersom det ikke blir tatt tak i denne manglende organiseringen, vil det kunne være til hinder for videre utbredelse og i verste fall virke ødeleggende for bevegelsen. Det må også pekes på kvinnenes sterke, til dels dominerende stilling / The international Safe-Community (SC) movement is steadily growing. This study highlights the so-called Affiliate Safe Community Support Centres (ASC) and their role in the movement. The concept of SC is treated as an innovation and an organisational model diffusing according to the theories of Rogers and Røvik. The ASCs are looked upon as ”change agencies” according to these theories. This is a case-study according to Yin of 9 out of 15 ASCs. Three of them have lost their status as ASC, six still have their status. The following five propositions are examined: 1.There are no differences in how the ASCs have executed their role that can explain why some have lost their status and some not. 2.The reason why some have lost their status can be explained by internal organisational, personal or economic conditions. 3.The ASCs and their tasks are not well known by the ”users”. 4.The ASCs have a weak or little conscious relations to the theoretical and scientific foundation of diffusion processes. 5.The SC-concept is to a very little degree considered as an organisational model. Data was collected from surveys and interviews with people at all ”levels” of the SC-movement as well as written material. All five propositions were strengthened by the material. The study leads to the following conclusions and recommendations which hopefully can improve the reputation and efficiency of the SC-movement and ease the work of the ASCs: The ASCs have an important role in the movement, but they are too few to serve an increasing number of SCs. The development of new ASCs should go on simultaneously with the increase of SCs. It is also necessary with a geographical distribution corresponding with the distribution of the SCs. The economy of the ASC-work has a very weak foundation, and this should be taken more seriously. There are conflicts between ASC-work and other tasks. There are no indications that certain models of internal organisation or company construction are more functional than others. Organisational matters are not considered sufficiently important. This is alarming, and may threaten the existence of the whole movement if not taken more seriously. It must be a responsibility of the WHO Collaborating Centre to bring these matters to discussion. There are few other arenas for these discussions than the regional and world-wide conferences. But in addition the institutions teaching SC-issues have a responsibility for taking up these topics in their education programmes. Women have a very strong position in the ASC. But it is not possible from this material to draw conclusions as to whether their position has influenced the priorities or choice of topics in the ASC-work. / <p>ISBN 978-9185721-08-5</p>

This dissertation is centered around a set of apparently conflicting intuitions that we may have about mathematics. On the one hand, we are inclined to believe that the theorems of mathematics are true. Since many of these theorems are existence assertions, it seems that if we accept them as true, we also commit ourselves to the existence of mathematical objects. On the other hand, mathematical objects are usually thought of as abstract objects that are non-spatiotemporal and causally inert. This makes it difficult to understand how we can have knowledge of them and how they can have any relevance for our mathematical theories. I begin by characterizing a realist position in the philosophy of mathematics and discussing two of the most influential arguments for that kind of view. Next, after highlighting some of the difficulties that realism faces, I look at a few alternative approaches that attempt to account for our mathematical practice without making the assumption that there exist abstract mathematical entities. More specifically, I examine the fictionalist views developed by Hartry Field, Mark Balaguer, and Stephen Yablo, respectively. A common feature of these views is that they accept that mathematics interpreted at face value is committed to the existence of abstract objects. In order to avoid this commitment, they claim that mathematics, when taken at face value, is false. I argue that the fictionalist idea of mathematics as consisting of falsehoods is counter-intuitive and that we should aim for an account that can accommodate both the intuition that mathematics is true and the intuition that the causal inertness of abstract mathematical objects makes them irrelevant to mathematical practice and mathematical knowledge. The solution that I propose is based on Rudolf Carnap's distinction between an internal and an external perspective on existence. I argue that the most reasonable interpretation of the notions of mathematical truth and existence is that they are internal to mathematics and, hence, that mathematical truth cannot be used to draw the conclusion that mathematical objects exist in an external/ontological sense.