This thesis deals with implementation of a new framework, which allows to define and generate demo data for the star schema structure. Work analyses and com-pares available demo data generators. In theoretical part of the thesis, there are described concepts and technologies using in the field of Business Intelligence. Practical part deals with the design and implementation of the framework. In the final section, there are actual examples of generated data and their possible rep-resentation (samples of possible reports and dashboards).

Le paysage médiatique arabe a connu un accroissement spectaculaire au cours de ces dernières décennies, notamment avec la création des grandes chaînes satellitaires comme Al-Jazeera, Al-Arabiya et MBC… et plus tard avec l’arrivée des chaînes occidentales arabophones à destination des publics arabes comme la BBC, France 24 et DW-TV Arabia. Les chaînes arabophones à destination du monde arabe constituent un phénomène médiatique pouvant servir des objectifs idéologiques, une diplomatie de séduction et des vecteurs d’influence pour atteindre des buts politiques et économiques. L’étude porte sur une de ces chaînes satellitaires, la DW-TV Arabia, et sur le rôle qu’elle joue pour le rayonnement de la culture et la position politique allemande, mais aussi pour promouvoir les valeurs et les pratiques démocratiques de la République fédérale. L’objet de cette recherche est de définir ses objectifs de création, sa ligne éditoriale dans la mesure où elle garantit la crédibilité, l’intégrité professionnelle, et son aptitude à forger un discours médiatique indépendant. Il convient par ailleurs de la situer dans le champ médiatique arabe mais aussi de montrer son rôle stratégique pour maintenir les intérêts économiques allemands dans le monde arabe. / The media landscape has known in the twentieth last years a spectacular increase, especially after the creation of satellite's channels with international vocation like Aljazeera, Al-Arabiya and MBC. Lately, the creation of occidental arabophones channels, like BBC, France 24 and DW-TV Arabia, comes to add a new dimension to the media field. The occidental arabophones channels that target Arab World can be considered as a phenomenon in the media field. They can be used to serving ideological objectives, to improve diplomatic relationships, and to make gains in politics and economics domains. This research is focalized in one of these channels; the DW-TV Arabia, this German channel in destination to the Arab World created in 2002. His role as a tool in the proliferation of Germany cultural and politics principles of the federal republic of Germany, to the Arab World, is one of the principals axes treated in this work. Therefore, the motifs of the creation of DW-TV Arabia occupy an important part of this study. The principal aspects who characterized the editorial line of this channel is based on the objectivity, credibility and independence; however, he play a strategic role in improving the economic interests of Germany in the Arab World countries.

Bakgrund: Individer med psykisk sjukdom har sämre hälsa och ökad dödlighet i somatiska sjukdomar jämfört med befolkningen i övrigt. Sjukdomstillstånden kan också leda till svårigheter att klara av vardagen och bidra till försämrad livskvalitet. Det är av stor vikt att sjuksköterskan får en tydlig bild av vad som påverkar livskvaliteten hos patienten och till hjälp finns ett antal olika instrument för att mäta hälsa och livskvalitet, bl.a. The Schedule for the Evaluation of Individual Quality of Life - Direct Weighting (SEIQoL-DW). Syfte: Att undersöka individuell livskvalitet hos patienter med psykisk sjukdom med hjälp av SEIQoL-DW, samt att undersöka patienters och behandlares uppfattning om instrumentets tillämpbarhet och användbarhet. Metod: Patienter inom den psykiatriska vården fyllde i SEIQoL-DW-formuläret med stöd av behandlare. Därefter fyllde båda parterna i en enkät om instrumentets användbarhet. Materialet analyserades kvantitativt och kvalitativt. Resultat: Patienterna som deltog i studien skattade Relationer/Socialt nätverk som det viktigaste livsområdet, följt av Arbete. Det område som upplevdes fungera bäst, det vill säga det område som hade högst nivå, var Familj. Lägst nivå hade Arbete, vilket var det område som fungerade sämst. De flesta patienter och alla behandlare ansåg att frågorna i formuläret var relevanta respektive angelägna, samt att formuläret kan vara ett bra stöd vid samtalet. Runt hälften av patienterna ansåg att det helt eller delvis tog lång tid att fylla i formuläret. Slutsats: Trots att livskvalitet är något individuellt anger många patienter samma livsområden som viktiga. Instrumentet är användarvänligt till stor del, men patienten kan behöva stöd för att fylla i formuläret. / Background: People with mental illness have poorer health and increased mortality from somatic diseases compared with the general population. The diseases can also lead to difficulties in coping with everyday life and reduced quality of life. It is very important that the nurse gets a clear picture of what affects the patient’s quality of life. There are a number of different instruments for measuring health and quality of life, e.g. The Schedule for the Evaluation of Individual Quality of Life - Direct Weighting (SEIQoL-DW). Aim: To examine individual quality of life amongst patients with mental illness with the assistance of SEIQoL-DW. The second aim was to study the feasibility and applicability of the instrument. Method: Patients in psychiatric care filled in the SEIQoL-DW-form with support of the health care staff. Then both the patient and the health care staff filled in a questionnaire about the instrument's usability. The material was analyzed quantitatively and qualitatively. Results: Patients participating in the study estimated Relationships/Social network as the most important area of life. The area that generally was perceived to work best was Family, Work had the lowest level. Most of the patients and all of the health care staff considered the instrument to be relevant and a good support for the dialogue. About half of the patients considered the form to be time-consuming. Conclusion: Although quality of life is something individual, many of the patients stated the same areas of life as important. The instrument is user-friendly to a great extent, but the patient may need assistance to complete the form.

Malignant melanoma (MM) is the deadliest skin cancer with an ever-increasing incidence. New treatments have improved the prognosis for patients with advanced MM. Still, most patients do not respond, and the side effects can be severe, underlining the need for better therapies. The overall aim of this thesis was to evaluate new means to improve the treatment for patients with advanced MM. Immunostimulatory gene therapy (AdCD40L) was evaluated in a clinical study and BRAF-inhibitory treatment in rare cases of BRAF-mutated MM. Due to its immunogenicity, MM is an attractive target for immunostimulatory gene therapy. AdCD40L is an adenovirus carrying the human gene for CD40 ligand, which in different ways can stimulate the immune system to combat cancer. We conducted a Phase I/IIa study with AdCD40L in patients with metastatic MM having received established treatments. In cohort 1 (n=6), four weekly, intratumoural AdCD40L injections were given. In cohort 2 (n=9), low dose cyclophosphamide was added to increase the immune response. Since irradiation may act synergistically with immunotherapy, patients in cohort 3 (n=9) also received a single fraction of radiotherapy (8 Gy). This fraction was given towards the lesion selected for injections. The primary objectives were to assess the feasibility and safety of AdCD40L-treatment and secondarily its anti-tumour effects. Patients were thoroughly assessed for toxicity. The anti-tumour response was evaluated by imaging techniques (FDG-PET/CT, DW-MRI scans), tumour biopsies and blood tests. Plasma protein markers were measured with a multiplex platform. Another objective was to evaluate the potential of DW-MRI and FDG-PET/CT for prediction of AdCD40L treatment response, in terms of overall survival (OS). AdCD40L was well tolerated with mild transient reactions. Local and distant responses in PET/CT scans along with a significantly better 6-month survival in the cohorts that received cyclophosphamide conditioning were observed. Effector lymphocyte responses were elicited. All patients had an increased T effector/T regulatory-cell ratio and death receptors were significantly up-regulated post therapy. Inflammatory cytokines and other plasma proteins were altered in favourable ways by the AdCD40L treatment. The analyses support that the functional DWI parameters may be better early predictors of OS than the established metabolic and morphologic criteria of FDG-PET/CT and CT/MRI, respectively. In conclusion, the stimulation of the CD40 pathway to initiate anti-tumour immunity is a promising treatment alternative for MM patients. However, further studies with developed treatment schemes are warranted. In the first report ever on treatment of a pregnant patient with a BRAF-inhibitor, the therapy was initiated in the second trimester. The treatment with vemurafenib enabled prolonged gestation, hence reducing the risk of immaturity-related complications. Further, we report the first case worldwide of a patient with metastatic conjunctival melanoma who benefitted from treatment with vemurafenib. Additional studies are needed to assess the efficacy of BRAF -inhibitors in the different subtypes of ocular melanoma.

No description available.

In der vorliegenden Arbeit wird analysiert, wie sich Pfade biografisch zunehmender Exklusion vom lebenslangen Lernen bei erwachsenen Lernern herausbilden, deren Erwerbsverläufe durch Instabilitäten und Diskontinuitäten gekennzeichnet sind. Die Analyse der drei in der einschlägigen Literatur diskutierten zentralen Vermittlungsinstanzen der Exklusion lässt neben dem allgemeinbildenden Schulabschluss als pfadinitiierendem Ereignis auch die zunehmende Bedeutung des Arbeitsmarkts im Hinblick auf die Strukturierung und Stabilisierung von Exklusionsrisiken sichtbar werden. Die frühzeitige Pfadinitiierung sowie die Identifikation asymmetrischer Machtverhältnisse als kontinuitätssichernde Mechanismen – verbunden mit der sichtbaren Tendenz zur Selbstexklusion – können als Desiderat einer verstärkten Berücksichtigung der jeweils vorliegenden Subjekt-Kontext-Relation der (potenziellen) Weiterbildungsteilnehmer verstanden werden. Wenn Konzepte lebenslangen Lernens breite inkludierende Wirkung entfalten sollen, erscheint öffentlich geförderte berufliche Weiterbildung notwendig, die sich verstärkt an der Formung der Person orientiert und nachhaltige, individuell als nützlich erfahrene Bildungsprozesse ermöglicht. / In the following work, we examine how exclusion affects the lifelong learning paths of adult learners, whose employment histories are often characterized by instability and discontinuity. The analysis of the three central facets often discussed in the literature of “exclusion,” allows for the ever increasing importance of the labour market in terms of structuring, and in the stabilization of “exclusion risks” along with general education as an initial “path” event. The results suggest the following conclusion: access to continuing education is often shaped by opportunity, and also individual demand. The attitude towards, or whether an individual engages in lifelong learning appears to be shaped early within a person. These early events of path dependency, as well as the identification of asymmetrical power relations as continuity assurance mechanisms, connected with the visible tendency to the exclusion of the self can be understood as a desideratum of reinforcement, which take into account the respective subject context relationship of (potential) participants in the educational program. If the concept of “lifelong learning for all” is to become a reality, or is to be of any effect, several aspects appear to be necessary; namely, a broad, public sponsored vocational training, that focuses on the formation of the individual, coupled with sustainable, requisite skills, and knowledge base.

Aus gesellschaftspolitischer und wissenschaftlicher Perspektive wird die Bedeutung digitaler Informations- und Kommunikationstechnologien (IKT) für Schule und Unterricht diskutiert. Dabei wird vor allem das Potenzial digitaler Medien zur Unterstützung konstruktivistischer Lehr-Lernprinizipien im Rahmen kooperativen und verständnisorientierten Unterrichts betont. Empirische Ergebnisse zeigen allerdings, dass das vorhandene Potenzial keineswegs ausgeschöpft wird. Im Rahmen der Lehrerkognitionsforschung wird angenommen, dass bewusste und weniger bewusste Kognitionen das unterrichtliche Handeln der Lehrpersonen determinieren. Vor diesem Hintergrund werden handlungsleitende Kognitionen von Lehrpersonen als Bedingungsfaktoren der Medienintegration in den Unterricht angesehen. In der vorliegenden Arbeit werden handlungsleitenden Kognitionen von Lehrpersonen beim Einsatz digitaler Medien im Unterricht rekonstruiert und das Verhältnis dieser zueinander analysiert. Im theoretischen Teil erfolgt die Beschreibung und Diskussion handlungsleitender Kognitionen von Lehrpersonen sowie von Unterricht. Dieser wird sowohl aus pädagogisch-psychologischer als auch didaktischer Perspektive beschrieben. Auf der Grundlage von Video- und Interviewdaten von Lehrpersonen der Sekundarstufe II, werden mithilfe inhaltsanalytischer und typisierender Verfahren drei differenzierte Überzeugungs- und drei Skriptmuster identifiziert. Die Unterrichtsskripts der Lehrpersonen unterscheiden sich in Bezug auf das Ausmaß der Lehrerlenkung, die Medienfunktion und -steuerung sowie hinsichtlich der Lehrer-Schüler-Interaktion. Die Überzeugungen der Lehrperso-nen unterscheiden sich in Bezug auf die angestrebte Lehrer- bzw. Schüler-Rolle und hinsichtlich der angestrebten Nutzung digitaler Medien im Unterricht. Es zeigen sich Übereinstimmungen zwischen Überzeugungen und Skripts, die auf zentrale lehr-lerntheoretische Vorstellungen zurückgeführt werden. / From a socio-political as well as scientific perspective the relevance of information and communication technology (ICT) for teaching and learning is often discussed. These discussions mostly center on the issue of the innovation of teaching and learning by the use of digital media. However, empirical studies indicate that teachers do not take advantage of the full potential of ICT in their teaching. Within the framework of teacher cognition research it is often assumed that the realized teaching behavior of teachers is determined by cognitions that guide the teaching. These cognitions have been further differentiated into beliefs on the one hand and automated cognitions (so called scripts) on the other. Thus, both constructs can serve as important indicators for the quality of media integration in teachers’ teaching. This study aims at the identification of guiding cognitions of teachers when using digital media at school. In the theoretical section the construct of teacher cognition is discussed and a framework for the reconstruction of teacher cognition is developed using both didactical concepts as well as results of instructional research. Based on interview and video data three different configurations of beliefs and scripts have been identified using typifying methods as well as content analysis. These scripts differ from each other with respect to the extent of teacher direction, the function and control of media in instruction and the type of teacher-student-interaction. The analysis of the teacher interviews indicates that the classroom behavior of teachers is based on a complex belief-system. The three types of teachers beliefs differ mainly in the perspective of the teacher- and student-role and in the perceived benefit of ICT for instruction. Overall, this study shows that teachers’ use of ICT in instruction is based on and directed by different guiding cognitions which can be described and typified from the perspective of teaching and learning.

Cette thèse est consacrée aux recherches des propriétés statiques et dynamiques des parois de domaines magnétiques (DW pour Domain Wall) dans les nanofils CoFeB. Un système de mesure basé sur un microscope Kerr à haute résolution a été mis en place et utilisé pour ces recherches.Tout d'abord, les phénomènes liés à la tension interfaciale des parois ont été étudiés. La contraction spontanée des bulles de domaine a été observée directement en utilisant le microscope Kerr. Ce phénomène a été expliqué en utilisant le concept de la pression de Laplace due à l'énergie interfaciale des parois. L'énergie interfaciale des parois a été quantifiée en mesurant le champ externe nécessaire pour stabiliser ces bulles. Le mécanisme de la piégeage et de la dépiégeage des parois dans certaines géométries artificielles, comme la croix de Hall ou l'entrée reliant un carré de nucléation et un fil, a été expliqué en utilisant le concept de tension interfaciale des parois et a été utilisé pour extraire l'énergie interfaciale des parois. Bénéficiant de ces études, une méthode permettant de quantifier directement le coefficient des Interactions de Dzyaloshinskii- Moriya (DMI pour Dzyaloshinskii- Moriya Interaction) à l'aide du microscope Kerr a été proposée. En outre, un nouveau type de capteur magnétique basé sur l'expansion réversible de paroi en raison de la tension interfaciale a été proposé et vérifié en utilisant des simulations micromagnétiques.Deuxièmement, les propriétés dynamiques des parois dans le film et les fils Ta / CoFeB / MgO ont été étudiées. La vitesse du propagation des parois induite par le champ magnétique ou par l'effet combiné des impulsions de champ magnétique synchronisées et des impulsions de courant électrique a été mesurée. En régime précessionne, la vitesse du mouvement DW induite par l'effet combiné du champ et du courant est égale à la superposition des vitesses entraînées par le champ ou le courant indépendamment. Ce résultat nous a permis d'extraire la polarisation de spin de CoFeB dans cette structure. Les effets de piégeage du mouvement des parois dans les fils étroits ont été étudiés. Des champs de dépiégeage associés aux gros défauts pour le mouvement des parois induit par champ dans les nanofils a été mesurée. Il a été constaté que les effets de piégeage deviennent plus sévères lorsque la largeur w des fils diminue. Une relation linéaire entre le champ de piégeage et 1/w a été trouvée. L'origine de ces sites d'ancrage durs ainsi que leurs influences sur la vitesse de mouvement des parois ont été discutées. En outre, il a été constaté que l'effet d'épinglage était amélioré lorsque le courant était appliqué, quelle que soit la direction relative entre le mouvement des parois et le courant. Cet accroissement pourrait être expliqué par l'effet du courant de Hall de spin de la sous-couche (Ta). Bien qu'il n'y ait pas eu de DMI ou de champ planaire, le courant de Hall de spin, polarisé dans la direction transversale, peut exercer un couple sur la parois de type de Bloch, une fois que la paroi s'éloigne de la direction transversale.Enfin, un dispositif mémoire de circuit en forme d'anneau basée sur le travail combiné de STT et SOT a été proposée. Comparée à la mémoire de piste traditionnelle en forme de ligne, cette mémoire en forme d'anneau permet au paroi de demaine de se déplacer dans un nanofil en forme d'anneau sans être éjecté, évitant ainsi la perte des informations associées. Le travail de conception et d'optimisation a été réalisé avec des simulations micromagnétiques. / This thesis is dedicated to the research of the static and dynamic properties of magnetic Domain Walls (DWs) in CoFeB nanowires. A measurement system based on a high-resolution Kerr microscope was implemented and used for these research.First, phenomena related to the DW surface tension was studied. A spontaneous collapse of domain bubbles was directly observed using the Kerr microscope. This phenomenon was explained using the concept of the Laplace pressure due to the DW surface energy. The surface energy of DW was quantified by measuring the external field required to stabilize these bubbles. The DW pinning and depinning mechanism in some artificial geometries, such as the Hall cross or the entrance connecting a nucleation pad and a wire, was explained using the concept of DW surface tension and was used to extract the DW surface energy. Benefited from these studies, a method to directly quantify the coefficient of Dzyaloshinskii- Moriya Interactions (DMI) using Kerr microscope has been proposed. In addition, a new type of magnetic sensor based on the revisable expansion of DW due to DW surface tension was proposed and verified using micromagnetic simulations.Second, the dynamic properties of DWs in Ta/CoFeB/MgO film and wires were studied. The velocity of DW motion induced by magnetic fields or by the combined effect of synchronized magnetic field pulses and electrical current pulses was measured. In steady flow regime, the velocity of DW motion induced by the combined effect of the field and the current equals to the superposition of the velocities driven by field or current independently. This result allowed us to extract the spin-polarization of CoFeB in this structure. Pinning effects of DW motion in narrow wires was studied. Depinning fields of hard pinning sites for the field-driven DW motion in nanowires was measured. It was found that the pinning effects become severer as the width w of the wires scaled down. A linear relationship between the depinning field and w was found. The origin of these hard pinning sites, as well as their influences on the DW motion velocity, was discussed. Furthermore, it was found that the pinning effect was enhanced when a current was applied, no matter the relative direction between the DW motion and the current. We propose a possible explanation, which would be an effect of the spin Hall current from the sublayer (Ta). Although there was no DMI or in-plane field, the spin Hall current, which was polarized in the transverse direction, can still exert a torque on the Bloch DW, once the DW tilts away from the transverse direction.At last, a ring-shaped racetrack memory based on the combined work of STT and has been proposed. Compared with the traditional line-shaped racetrack memory, this ring-shaped memory allows the DW moving in a ring-shaped nanowire and the data dropout problem can be avoided. The design and optimization work was performed with micromagnetic simulations.

健康相關生活品質越來越重視病人主觀的感受，然而將這個部分納入測量之後，許多研究結果卻出現殘疾悖論(disability paradox)的現象，也就是重度疾病病人的自評生活品質並不比程度輕微或甚至健康的人差。反應轉移理論認為，造成這個現象的原因在於個人的自評生活品質會受到個體對於生活品質定義的改變（重新構念）、內在測量尺度標準的改變（重新校準）、以及價值的改變（重新權重）的影響，到目前為止，反應轉移尚未發展出合適的測量工具。 SEIQoL-DW (Schedule for the Evaluation of Individual Quality of Life- direct weighting)做為一個生活品質測量個人化的代表，其評估分成三個步驟，分別是提名重要的生活領域、評估提名領域的滿意程度、以及評估提名領域的相對權重，許多研究者嘗試用SEIQoL-DW在兩點間的領域變化做為重新構念，權重變化做為重新權重，重新校準則需要搭配then test來測量，then test是在第二個測量點時邀請受試重新對第一個時間點的提名領域進行評估，然而這三個成分指標的操作型定義不一，then test也有使用上的不便，同時過去這些指標對生活品質的效用檢驗也都未達顯著。本研究分認為，若能解決上述的問題，將有助於解釋殘疾悖論，同時可以區辨不同類別病人的反應轉移模式，並運用在臨床來幫助病人進行調適。 本研究以立意取樣招募3期以上之慢性腎臟病患者、以及血液透析、腹膜透析未滿一年以上之三組病患共85名，除了背景和臨床資料外，在間隔三個月的兩點分別填寫SEIQoL-DW、ideal scale（評估期待）、生活滿意問卷、正負向情緒問卷，並在後測時填寫then test。研究結果顯示，三組病人的生活品質符合殘疾悖論，並無顯著差別。重新構念、重新校準、和重新權重當中，僅重新校準有助於生活品質的提升，並能夠顯著解釋生活品質的改變。 對腎臟病患者來說，期待越高，生活品質提升得越多，進一步的分析顯示，受試會捨棄相對權重較低的領域，新提名領域的滿意程度、期待、和相對權重都顯著高於捨棄的舊領域，這可以作為臨床上協助病人調適的策略。雖然then test的結果顯著，但實證結果和理論卻相當混亂，尚待未來研究釐清。 / Health-related quality of life (HRQoL) is increasingly recognized as being subjective, which emphasized patient-reported outcomes. Many HRQoL studies reported that people with serious illness perceived no less quality of life (QoL) than those without such illness. This phenomenon is labeled as disability paradox. Response shift theory provides an explanation for it and refers to a change in the meaning of one’s self-evaluation of QoL as a result of changes in internal standards (recalibration), values (reprioritization), and reconceptualization of QoL. It is these changes that will influenced perceived QoL. Current methods to detect Response Shift are still evolving. SEIQoL-DW (Schedule for the Evaluation of Individual Quality of Life- direct weighting) is one of individualized QoL instruments and measures three elements of QoL, including five important aspects of life, current satisfaction with each aspect, and relative importance of each aspect. Many researchers tried to use SEIQoL-DW to detect response shift. Changes in the content of aspects of life between two time points reflect reconceptualization. Changes in the relative weighting between two time points reflect reprioritization. Recalibration is measured by then test, which is a method by asking respondents at time two to provide a renewed rating of their aspects of life given at time one. However, there are no consensus operational definition of indices of reconceptualization , reprioritization, and recalibration. The examination between indices and improvements in QoL was not significant, either. Besides, then test with SEIQoL-DW has a disadvantage when aspects nominated between time one and two are different. This study tried to resolve issues above. If these issues are resolved, disability paradox will be explained. Response Shift will possibly differentiate patients of various disease, and provide ideas to help patients adjust to illness. 85 patients were recruited, including those with renal disease stage 3-5, and those undergoing hemodialysis or peritoneal dialysis within one year. All patients completed SEIQoL-DW, ideal scale, Satisfaction with Life Scale, the Positive And Negative Affect Scale at time one and three months after , except questionnaire on personal background and biological information (at time one) and then test (at time two). Results indicated that the QoLs of these three groups of patients showed no different, which confirmed disability paradox. Only recalibration showed helpful. Regression analyses also showed that recalibration indices were better predictors in QoLs. For End-stage Renal Disease patients, higher expectation suggested higher QoL improvement. Further analysis showed that patients would abandon lower-weighted aspect of life. Compared to the abandoned aspects, higher satisfaction, expectation and weighting were seen in new-nominated aspect. This finding could be useful in helping patients adjust. Although then test also reached significance, evidences was contradicted to its prediction. More research is needed in the future.

In dieser Arbeit wird am Beispiel der Integrierten Fortbildung der Polizei des Landes Brandenburgs untersucht, wie eine grundlegende Reorganisationsmaßnahme durch die verhaltensorientierte Fortbildung unterstützt werden kann. Es werden Möglichkeiten aufgezeigt, die im Rahmen eines Reformprozesses nötigen Verhaltensänderungen mit Hilfe der organisationseigenen Fortbildungsstruktur zu erreichen. Die Änderung von eingeschliffenen Verhaltensweisen bei Erwachsenen hat sich in der Praxis als sehr problematisch erwiesen. Deshalb wird in dieser Arbeit zunächst die Frage geklärt, welche Impulse von den aktuellen Forschungsergebnisse der Neurophysiologie und der Erziehungswissenschaften für eine Weiterentwicklung der verhaltensorientierten Fortbildung von Erwachsenen ausgehen können. Weiterhin wird untersucht, mit welcher konkreten Methodik sich langfristige und praxiswirksame Verhaltensänderungen bei Erwachsenen erreichen lassen und wie diese evaluiert werden können. Mit dieser Arbeit wird ein Konzept für eine verhaltensorientierte Fortbildung von Erwachsenen vorgestellt, das sowohl den Erfordernissen der Organisationsentwicklung als auch des täglichen Dienstes gerecht wird. Die Ergebnisse der Arbeit haben nicht nur für Fortbildungsmaßnahmen innerhalb der Polizei Gültigkeit, sondern sie lassen sich auch auf andere Bereiche übertragen, in denen Erwachsene innerhalb einer hierarchisch organisierten Struktur zu einer Änderung althergebrachter Verhaltensweisen veranlasst werden sollen. Wichtige Impulse gibt die Arbeit für die Fortbildung von Erwachsenen, die im Rahmen ihrer Tätigkeit auch unter extremen Stressbedingungen handlungsfähig bleiben sollen. Umsetzbar wäre dieses Konzept also auch in der Fortbildung von Feuerwehrleuten, Militärangehörigen, Lehrern, Erziehern oder von Personal in Krankenhäusern. / Using the example of the integrated further education of the police of the land Brandenburg this paper examines how a profound measure of reorganisation can be supported by a behaviour oriented further education. Possibilities are being shown of how to achieve the necessary behavioural changes within the larger frame of a reform process with the help of a framework of further education within the organization itself. Changing established patterns of behaviour of adults has proved to be very difficult in practice. Therefore this paper first of all settles the question which impulses a further development of behaviour oriented further education of adults could receive from research results of neurophysiology and educational science. Further it is being investigated which specific methods can be employed to achieve a long-term change in the patterns of behaviour of adults which are effective in practice and how they can be evaluated. This study introduces a concept for a behaviour oriented further education of adults which does justice to the demands of the organization‘s development as well as of the daily duties. The results of the study are not only valid for the further education measures within the police but they can also be transferred to other areas in which adults are to be made to change established patterns of behaviour within a hierarchically organized structure. The study provides important impulses to the further education of adults who are to remain capable of acting within in the frame of their work even under extreme pressure. This concept therefore could also be applied to further education of firemen, military personnel, teachers, educators, and the personnel of hospitals.