• Refine Query
  • Source
  • Publication year
  • to
  • Language
  • 28
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • Tagged with
  • 45
  • 45
  • 17
  • 17
  • 15
  • 11
  • 11
  • 9
  • 8
  • 8
  • 7
  • 6
  • 6
  • 6
  • 5
  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

La vie rurale en Syrie centrale à la période protobyzantine (IVe-VIIe siècle). / Rural life in Central Syria in the early Byzantine period (4th-7th century).

Rivoal, Marion 15 March 2011 (has links)
La Syrie centrale connaît au début de la période byzantine, et en particulier au Ve et au VIe siècle, un fort mouvement d’expansion des sédentaires vers l’est, qui coïncide avec une importante mise en valeur de ces nouveaux territoires. Comme pour d’autres régions de Syrie et du Proche-Orient à la même époque, un optimum climatique – pourtant déclinant – semble avoir permis la conquête et l’exploitation agricole de nouveaux terroirs dans une zone marginale qui n’avait jusqu’alors connu qu’une occupation sédentaire ponctuelle. La Syrie centrale est caractérisée par des milieux aux potentiels agronomiques très différents, souvent imbriqués. Le peuplement et la mise en valeur y sont soumis à la double contrainte de l’aridité climatique et édaphique, qui s’exerce avec une prégnance croissante vers le sud et l’est. Ces conditions, qui s’améliorent localement à la faveur de niches écologiques, ont permis à des politiques de mise en valeur et à des économies distinctes, souvent complémentaires, de voir le jour.Dans une région où les cités paraissent en grande partie absentes, l’économie repose d’abord sur les villages et sur quelques bourgs qui possédaient manifestement une orientation commerciale spécifique. Aux côtés des agglomérations, et souvent d’autant plus nombreux que les conditions d’implantation sont délicates, des fermes et des monastères s’affirment comme des acteurs économiques apparemment indépendants et souvent prospères. Des entités géographiques relativement homogènes ont donné lieu à une répartition des différentes formes de peuplement et à des économies microrégionales spécifiques. Si l’agriculture vivrière reste la règle, il semble bien cependant qu’on observe une spécialisation locale des productions : culture du blé et accessoirement plantations à l’ouest, oléiculture et peut-être viticulture dans les plateaux basaltiques du nord-ouest et vraisemblablement un élevage spéculatif, qu’on doit probablement attribuer à des populations sédentaires, dans les secteurs sud et est. / In Late Antiquity, especially between the 5th and 6th centuries, Central Syria witnessed a strong expansion of sedentary settlements eastward, which coincided with a significant agricultural development of these new territories. As for other areas in Syria and Near-East at the same period, a waning climatic optimum seems to have allowed byzantine population to settle down in marginal areas which barely experienced hitherto sedentary occupation and farm nearly unbroken lands.Central Syria is made up of various landscapes, sometimes deeply nested, with contrasted agricultural potential. Settlements and agricultural exploitation are affected by an increasingly significant climatic and edaphic aridity eastward and southward. These conditions, which may locally improve thanks to ecological niches, enabled specific and often complementary substance strategies to develop.In a country whence cities are virtually absent, villages and a few market towns seem to be at the very root of the regional economy. Along with agglomerations, scattered habitats – namely farmsteads and monasteries –, more numerous under heavy bioclimatic constraints, would appear as independent and apparently prosperous economic players.Homogeneous geographic areas led to specific settlement patterns and different economic orientations. Food-producing agriculture remains the rule, but a local productive specialization may be noticed: mainly wheat production and incidentally plantations westward, olive-growing and maybe wine-growing as well in the north-west basaltic plateaus and presumably speculative livestock exploitation eastward and southward, probably mostly due to sedentary populations.
42

Effects of iron and omega-3 supplementation on the immune system of iron deficient children in South Africa : a randomised controlled trial / Linda Malan

Malan, Linda January 2014 (has links)
Background Iron deficiency (ID) is the world‟s most prevalent micronutrient deficiency and predominantly affects developing countries, also South Africa. In areas with low fish consumption and high n-6 PUFA vegetable oil intake, there is a risk for having inadequate n-3 PUFA status. Both iron and n-3 PUFA play important roles in the immune response, and supplementation is a strategy to alleviate deficiencies. However, little is known about potential interactive effects between concurrent iron and n-3 PUFA supplementation on the immune system. This is also important in the context that iron supplementation may be unsafe and may increase morbidity and mortality. Aim The overall aim of this thesis was to assess the effects of iron and docosahexaenoic (DHA)/eicosapentaenoic acid (EPA) supplementation, alone and in combination, on the immune system of ID children. More specifically, these effects were investigated on the occurrence and duration of illness and school-absenteeism due to illness, peripheral blood mononuclear cell (PBMC), red blood cell (RBC) and plasma total phospholipid fatty acid composition, iron status, fatty acid-derived immune modulators and targeted PBMC gene expression. Furthermore, association of PBMC, RBC and plasma total phospholipid fatty acid composition with allergic disease, were also examined. Design In a 2-by-2 factorial, randomised, double-blind, placebo-controlled trial, South African children (n = 321, aged 6–11 y) were randomly assigned to receive oral supplements of either 1) iron (50 mg as ferrous sulphate) plus placebo; 2) DHA/EPA (420/80 mg) plus placebo; 3) iron plus DHA/EPA (420/80 mg); or 4) placebo plus placebo for 8.5 mo, four times per week. Absenteeism and illness symptoms were recorded and biochemical parameters for compliance as well as parameters fundamental to immune function were assessed at baseline and endpoint. Furthermore, in a cross-sectional design, associations of allergic disease with baseline fatty acid composition of PBMC, RBC and plasma were examined. Results The combination of iron and DHA/EPA significantly attenuated respiratory illness caused by iron supplementation. DHA/EPA supplementation alone improved respiratory symptoms at school, but increased headache-related absenteeism. DHA/EPA and iron supplementation individually tended to increase and decrease anti-inflammatory DHA and EPA-derived mediators, respectively. Furthermore the anti-inflammatory DHA-derived immune mediator, 17HDHA was higher in the DHA/EPA plus placebo and iron plus DHA/EPA groups than in the iron plus placebo group. Also, the pro-inflammatory arachidonic acid (AA)-derived modulators (5- and 15-hydroxyeicosapentaenoic acid) were significantly lower in the iron plus DHA/EPA group compared to the placebo plus placebo groups. In the study population, 27.2% of the children had allergic disease and AA in PBMC phospholipids was significantly lower in the allergic children than in the non-allergic children. In RBC phospholipids dihomo-gamma-linolenic acid (DGLA) and the ratio of DGLA: linoleic acid (LA) correlated negatively and the n-6:n-3 PUFA ratio positively with total immunoglobulin E (tIgE). Furthermore, trans-C18:1n-9, tended to be higher in the allergic group. Conclusion DHA/EPA prevented respiratory illness caused by iron supplementation and although DHA/EPA on its own reduced respiratory morbidity when the children were present at school, surprisingly it increased the likelihood of being absent with headache and fever. The biochemical findings compliment the clinical results and support previous observations about DHA/EPA supplementation to reduce inflammation, but add to the current knowledge base that a relatively high oral dose of non-haem iron modulates circulating lipid-derived immune modulators and related gene expression. Furthermore, when supplementing with iron and DHA/EPA combined, in this ID population with low fish intake, the anti-inflammatory effect of DHA/EPA is maintained concurrently with attenuation of respiratory morbidity. This finding support the notion that excess iron (probably as non-transferrin bound iron) becomes available for pathogens and is probably why we found that iron increased respiratory infectious morbidity. The improved clinical outcome with combined supplementation seems to be related to increased lipid-mediator synthesis gene expression and the availability of DHA/EPA, leading to a more pro-resolving profile and enhanced immune competence. Overall these results give better insight into immune function and infectious morbidity in relation to n-3 PUFA and iron status and treatment, as well as the possible association of fatty acid status with allergic disease in young South-African school children. / PhD (Nutrition), North-West University, Potchefstroom Campus, 2015
43

Effects of iron and omega-3 supplementation on the immune system of iron deficient children in South Africa : a randomised controlled trial / Linda Malan

Malan, Linda January 2014 (has links)
Background Iron deficiency (ID) is the world‟s most prevalent micronutrient deficiency and predominantly affects developing countries, also South Africa. In areas with low fish consumption and high n-6 PUFA vegetable oil intake, there is a risk for having inadequate n-3 PUFA status. Both iron and n-3 PUFA play important roles in the immune response, and supplementation is a strategy to alleviate deficiencies. However, little is known about potential interactive effects between concurrent iron and n-3 PUFA supplementation on the immune system. This is also important in the context that iron supplementation may be unsafe and may increase morbidity and mortality. Aim The overall aim of this thesis was to assess the effects of iron and docosahexaenoic (DHA)/eicosapentaenoic acid (EPA) supplementation, alone and in combination, on the immune system of ID children. More specifically, these effects were investigated on the occurrence and duration of illness and school-absenteeism due to illness, peripheral blood mononuclear cell (PBMC), red blood cell (RBC) and plasma total phospholipid fatty acid composition, iron status, fatty acid-derived immune modulators and targeted PBMC gene expression. Furthermore, association of PBMC, RBC and plasma total phospholipid fatty acid composition with allergic disease, were also examined. Design In a 2-by-2 factorial, randomised, double-blind, placebo-controlled trial, South African children (n = 321, aged 6–11 y) were randomly assigned to receive oral supplements of either 1) iron (50 mg as ferrous sulphate) plus placebo; 2) DHA/EPA (420/80 mg) plus placebo; 3) iron plus DHA/EPA (420/80 mg); or 4) placebo plus placebo for 8.5 mo, four times per week. Absenteeism and illness symptoms were recorded and biochemical parameters for compliance as well as parameters fundamental to immune function were assessed at baseline and endpoint. Furthermore, in a cross-sectional design, associations of allergic disease with baseline fatty acid composition of PBMC, RBC and plasma were examined. Results The combination of iron and DHA/EPA significantly attenuated respiratory illness caused by iron supplementation. DHA/EPA supplementation alone improved respiratory symptoms at school, but increased headache-related absenteeism. DHA/EPA and iron supplementation individually tended to increase and decrease anti-inflammatory DHA and EPA-derived mediators, respectively. Furthermore the anti-inflammatory DHA-derived immune mediator, 17HDHA was higher in the DHA/EPA plus placebo and iron plus DHA/EPA groups than in the iron plus placebo group. Also, the pro-inflammatory arachidonic acid (AA)-derived modulators (5- and 15-hydroxyeicosapentaenoic acid) were significantly lower in the iron plus DHA/EPA group compared to the placebo plus placebo groups. In the study population, 27.2% of the children had allergic disease and AA in PBMC phospholipids was significantly lower in the allergic children than in the non-allergic children. In RBC phospholipids dihomo-gamma-linolenic acid (DGLA) and the ratio of DGLA: linoleic acid (LA) correlated negatively and the n-6:n-3 PUFA ratio positively with total immunoglobulin E (tIgE). Furthermore, trans-C18:1n-9, tended to be higher in the allergic group. Conclusion DHA/EPA prevented respiratory illness caused by iron supplementation and although DHA/EPA on its own reduced respiratory morbidity when the children were present at school, surprisingly it increased the likelihood of being absent with headache and fever. The biochemical findings compliment the clinical results and support previous observations about DHA/EPA supplementation to reduce inflammation, but add to the current knowledge base that a relatively high oral dose of non-haem iron modulates circulating lipid-derived immune modulators and related gene expression. Furthermore, when supplementing with iron and DHA/EPA combined, in this ID population with low fish intake, the anti-inflammatory effect of DHA/EPA is maintained concurrently with attenuation of respiratory morbidity. This finding support the notion that excess iron (probably as non-transferrin bound iron) becomes available for pathogens and is probably why we found that iron increased respiratory infectious morbidity. The improved clinical outcome with combined supplementation seems to be related to increased lipid-mediator synthesis gene expression and the availability of DHA/EPA, leading to a more pro-resolving profile and enhanced immune competence. Overall these results give better insight into immune function and infectious morbidity in relation to n-3 PUFA and iron status and treatment, as well as the possible association of fatty acid status with allergic disease in young South-African school children. / PhD (Nutrition), North-West University, Potchefstroom Campus, 2015
44

The economics of exchanging and adopting plant genetic resources for food and agriculture / Evidence from Germany and Peru

Lüttringhaus, Sophia 09 March 2022 (has links)
Landwirtschaftliche Systeme müssen sich immerfort an Druckfaktoren wie Klimawandel und Bevölkerungswachstum anpassen. Hierbei spielt die genetische Vielfalt von Pflanzen eine wichtige Rolle, da diese für die Sicherung der Ernährung und des Einkommens von entscheidender Bedeutung ist. Dennoch wird der wirtschaftliche Wert pflanzengenetischer Ressourcen selten untersucht. Um diese Forschungslücke zu schließen, werden in dieser Arbeit drei Bewertungen vorgestellt, welche die wirtschaftlichen Werte pflanzengenetischer Ressourcen untersuchen. Im Rahmen dieser Dissertation werden zwei verschiedene Agrarsystemen analysiert. Diese unterscheiden sich hinsichtlich des Klimas, der agrarökologischen Bedingungen, der landwirtschaftlichen Praxis, der politischen und ökonomischen Rahmenbedingungen sowie der soziokulturellen Verankerung der Kulturart. Die ersten beiden Analysen befassen sich mit der Züchtung und Produktion von Winterweizen in Deutschland. Charakterisiert sind diese durch ein gemäßigtes Klima und intensive Anbaubedingungen. In diesem System überwiegen moderne Sorten, die in einem formalisierten Züchtungsprozess entstanden sind. Es werden die folgenden Forschungsfragen beantwortet: 1) Was ist der ökonomische Wert, der durch den Austausch von Zuchtmaterial entsteht? und 2) Wie hoch ist der mikroökonomische Wert von Resistenzzüchtung? In der dritten Analyse wird ein weiteres Agrarsystem vorgestellt: Die Andenlandwirtschaft, wo im Hochland unter extensiven Bedingungen eine Vielzahl von Kartoffellandrassen angebaut wird. Dort wird folgende Frage analysiert: 3) Welche Mehrwerte wurden durch die Repatriierung oder Neuverteilung von Kartoffellandrassen erzielt? Diese Analysen zeigen, dass die Verfügbarkeit, der Austausch und die Nutzung von pflanzengenetischen Ressourcen die Agrarproduktion verbessern; es entstehen sowohl sektorale, mikroökonomische als auch ernährungsbezogene und kulturelle Mehrwerte. / Agricultural systems must constantly adapt to pressuring events such as climate change and population growth to maintain and improve production processes in a sustainable manner. Thereby the genetic diversity of plants used in agriculture constitute a strategic asset. Nevertheless, their economic value is often overlooked. To fill this research gap, this thesis presents three assessments that produce more evidence on the economic value of plant genetic resources. Two very distinct agricultural systems are discussed. These differ greatly in terms of climate, agroecological conditions, farming practices, seed systems, political and economic frameworks, and the socio-cultural embeddedness of the crop in question. The first two assessments are concerned with winter wheat (Triticum aestivum) breeding and production in the temperate climate and intensive growing conditions in Germany. Modern cultivars created in a formalized breeding process prevail in this system. The following two research questions are elaborated: 1) What is the economic value of exchanging breeding material? and 2) What is the microeconomic value of resistance breeding? The third assessment presents a different agricultural system: Andean agriculture, where a wide variety of potato landraces (Solanum spp.) are grown extensively in the Peruvian highlands. In this case, the research question I investigated is: 3) What are the benefits of repatriating (i.e., redistributing) potato landraces to Andean farmers? These studies demonstrate that the availability, exchange, and adoption of plant genetic resources, which are well adapted to and culturally embedded in specific agricultural systems, improve the overall quantity and sustainability of agricultural production. These improvements can be translated into sectoral, microeconomic as well as nutritional and cultural benefits.
45

Relationen mellan WHO:s globala aidsprogram och icke­statliga organisationer : Kan bristen på samarbete förklaras utifrån new interdependence approach eller medlemsstaternas agerande? / Relations Between WHO Global Programme on AIDS and NGOs : Can the lack of cooperation be explained by new interdependence approach or the actions of member states?

Tengdelius, Daniel January 2023 (has links)
This thesis aims to understand why the World health organization’s Global programme on aids (WHO GPA) does not appear to be able to collaborate with non-governmental actors (NGO), even though booth WHO GPA and NGO`s appears to value and seek cooperation. The purpose of this thesis is to examine whether the lack of cooperation between WHO GPA and NGO: s can be explained using new interdependence approach or if the actions of WHO´s member states v. The selected case in this thesis is WHO GPA which existed from 1987 to 1995 and represents the first anti-aids program supported by UN and its member states. WHO GPA is therefore active in a policy area where a lot of interactions with NGO: s could be expected. To analyse the apparent lack of cooperation between WHO GPA and relevant NGO: s, this article will apply the theories new interdependence approach and neorealism. To explain the research questions, how does the interaction between WHO GPA and NGO: s appear within the global effort against the aids pandemic, what role did member states have in limiting or enable formal cooperation between WHO GPA and NGO:s and finally how the theory new interdependence approach can explain the interactions between the WHO GPA and NGO: s. To answer the research questions this thesis will apply a qualitative text analysis on material from WHO GPA, for example annual reviews, as well as previous research articles and books that concerns the WHO GPA. The analysis concludes that the interaction between WHO GPA and NGO: s, can be explained with the fact that informal cooperation does appear but not formal cooperation. This appears to be because while booth WHO GPA and NGO: s seeks support and cooperation, the interactions between them is still affected by mistrust. The member state’s role in limiting or enabling cooperation can be answered two levels, globally where powerful states have strong informal powers to control WHO GPA. When NGO: s are granted formal representation, the selection of NGO: s is not representative of the larger NGO community and not in response to cooperation between WHO GPA and NGO:s. Recipient states does also appear to hinder cooperation between NGO:s, WHO GPA and national aids programmes, because of rivalry between the state and NGO over limited aid. Finally, new interdependence approach appears to explain to lack of formal cooperation, because of a lack of distinct resources. However, it cannot explain the cases where NGO: s achieved official representation as the result of cross-national layering.

Page generated in 0.0735 seconds