The objective of the thesis is to provide a better understanding of the safety conditions inurban environments, particularly related to those found in transport nodes, in this case,underground stations, and surrounding areas1. First, the study starts with an analysis of theoverall city, identifying concentrations of crime in the urban fabric and then focusing on thecriminogenic conditions at and around underground stations. The analysis combines the useof Geographical Information Systems (GIS), statistical techniques and data of different typesand sources. Regression models were used to assess the importance of the environmentalattributes of underground stations on crime rates. Findings show that violent and propertycrimes show different hotspots at different times. Crime patterns tend to follow people’sscheduled patterns of routine activity. The socio-economic composition of the surroundingenvironment of the stations has a significant impact on crime at these transport nodes, butmore important were attributes of the physical and social environment at the stations. Forinstance, low guardianship and poor visibility at the stations together with mixed land-usesin the surrounding areas induced crime rates at the stations. It is therefore suggested thatintervention to improve safety conditions at the stations should focus on a holistic approach,taking into account the station and surrounding areas, but also being aware of crimevariation on specific places at specific times. / <p>QC 20130207</p> / Safety in transport nodes: the influence of environmental attributes on crime and perceived safety

Die Entwicklungszeiten in der Automobilindustrie werden immer kürzer, die Produktpalette deutlicher breiter und die Anforderungen an Insassen- und Fußgängerschutz immer höher. Dafür müssen aus Sicht eines Engineeringdienstleisters Konzepte bereitgestellt werden, welche gut individualisierbar sind, mit geringem Aufwand an unterschiedliche Anwendungsszenarien angepasst werden können und gleichzeitig abgesichert sind. Dies ist insbesondere für das noch junge Feld der Elektromobilität von Bedeutung. Gerade hier sind flexible Konzepte wichtig, da neben den etablierten OEM auch neue Wettbewerber erscheinen. Für diesen Zweck wird bei EDAG ein Technologieträger einer modularen Zusatzbatterie entwickelt, welches auf einer Struktur aus Halbzeugen (Strangpressprofile) in Kombination mit individualisierbaren, funktionsintegrierten, additiv gefertigten Knoten basiert. Die Struktur der Knoten ist mittels Topologieoptimierung auf einen Crashlastfall ausgelegt und außerdem die Funktionen zur Medienverteilung, Profilanbindung, Karosserieversteifung und Halteelemente integriert. Nachfolgend werden die für die Entwicklung dieses Bauteils nötigen Grundlagen, der aktuelle Projektstand und der Engineeringprozess beschrieben. [... aus der Einleitung]

In recent years, the interest in Augmented Reality (AR) applications for entertainment and productivity has grown. One company exploring this technology is LAZER WOLF STUDIOS, the developers behind Thrymd: an AR-driven board games platform powered by the Unity engine.  This paper details the development of a visual scripting framework, meant to provide end users with a means of developing their own games for the platform, without significant programming or background knowledge required. A graph-based visual language was implemented in a custom Unity editor window, in order to maintain a familiar and consistent feel for users. The graph consists of a series of branching, interconnected nodes which pass data in-between each other, and execute in succession. The graph is serialized as a Unity asset, and can easily be interacted with through regular C# scripts.  A small number of nodes were implemented, but for the system to be viable, more are needed. For that reason, extensibility was a core ideal; creating new node types must be fast and painless. As with any script layer, performance is generally worse than compiled code. Further work is needed to improve user experience. / Intresset för användandet av Augmenterad Verklighet (AR) för underhållning och produktivitetssyften har ökat på senare tid. LAZER WOLF STUDIOS är utvecklarna bakom Thrymd, en AR-driven brädspelsplattform byggd i spelmotorn Unity.  Denna rapport dokumenterar utvecklingsprocessen av ett visuellt skriptramverk byggt med avsikt att låta slutanvändare utveckla sina egna spel till plattformen utan större förkunskapskrav. Ett graf-baserat visuellt skriptspråk implementerades i en skräddarsydd editormiljö inuti Unity, för att bibehålla en bekant och konsekvent användarupplevelse. Grafen består av en serie förgrenande, sammankopplade noder som skickar data mellan varann och exekveras i sekvens. Grafen sparas som en resurs på hårddisken och är lätt att interagera med genom traditionella C#-skript i Unity.  Ett mindre antal noder implementerades, men fler krävs för att systemet ska vara brukbart. Av detta skäl designades språket med vidareutveckling i åtanke, då det måste vara enkelt att skapa nya noder. Som med de flesta skriptspråk är prestandan överlag sämre än kompilerad kod. Ytterligare arbete krävs för att förbättra användarupplevelsen.

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The city of Falun has a rich history of mining with the open mine, Stora Stöten, centrally located in the city and nowadays a well-known world heritage tourist attraction. The mine is the main reason that Falun even exists. During its glory days, Falun was one of Sweden’s largest cities, at that time considered to be world-leading in mine engineering and Europe’s main supplier of copper.  A less flattering effect of the mining era was that the city became poisonous and almost unhabitable. Both waters from the mine and from piles of mining waste ended up in rivers and lakes around Falun. Over the years several successful actions have been taken to improve and restore the environment which has decreased the amount of heavy metals leaked into Faluån and lake Tisken. Though, the water is still polluted, and Tisken has in practice for a long period of time worked as a deposit with an increasing amount of poisonous sediments.  This has unfortunately made Falun central waterbodies disabled for human use and made humans no longer have a relationship to the water despite its central location, importance, and potential for the city.  This thesis project seeks to unlock the lost potential of water in Falun by reviving it as a living and interweaved spine in the city in a systematic and schematic approach. The project aims to address the polluted water and sediment challenges while promoting sustainable stormwater and flooding management. A connected green structure linked with a movement network for pedestrians and bicyclists promotes sustainable transport to the spine and existing nodes in the city. The different layers in the project enable new nodes with new potentials for Falun

Yes / As 5th Generation research reaches the twilight, the research community must go beyond 5G and look towards the 2030 connectivity landscape, namely 6G. In this context, this work takes a step towards the 6G vision by proposing a next generation communication platform, which aims to extend the rigid coverage area of fixed deployment networks by considering virtual mobile small cells (MSC) that are created on demand. Relying on emerging computing paradigms such as NFV (Network Function Virtualization) and SDN (Software Defined Networking), these cells can harness radio and networking capability locally reducing protocol signalling latency and overhead. These MSCs constitute an intelligent pool of networking resources that can collaborate to form a wireless network of MSCs providing a communication platform for localized, ubiquitous and reliable connectivity. The technology enablers for implementing the MSC concept are also addressed in terms of virtualization, lightweight wireless security, and energy efficient RF. The benefits of the MSC architecture towards reliable and efficient cell-offloading are demonstrated as a use-case. / This project has received funding from the European Union's H2020 research and innovation program under grant agreement H2020-MCSAITN- 2016-SECRET 722424 [2].

Angeborene lymphoide Zellen (ILCs) bilden eine Familie von Effektorzellen des angeborenen Immunsystems, denen somatisch rekombinierte Antigenrezeptoren fehlen und die in drei Hauptgruppen eingeteilt werden. In der Embryonalentwicklung spielen Typ 3 ILCs, sogenannte LTi (Lymphoid Tissue inducer) Zellen, eine zentrale Rolle in der Entwicklung von Lymphknoten. ILC3, einschließlich LTi Zellen sind abhängig von dem Master-Transkriptionsfaktor RORgt, was sich in RORgt-defizienten Mäuse durch die Abwesenheit aller ILC3, und auch durch fehlende Lymphknoten äußert. Während postnatale Ko-expression der Transkriptionsfaktoren T-bet und RORgt in ILC3-Subpopulationen fest etabliert ist, ist der Einfluss von T-bet in fötalen ILC3 und auf die Generation von Lymphknoten noch unbekannt. Um diese Mechanismen genau zu untersuchen, wurden fötale ILCs mittels Einzelzell-RNA-Sequenzierung charakterisiert, wodurch eine unerwartete Heterogenität innerhalb der ILC3 mit T-bet-exprimierenden Zellen aufgedeckt wurde. Außerdem wurden PLZF+ ILC-Vorläufer (ILCP) im sich entwickelnden Darm nachgewiesen. Weiterhin, bestätigen diverse Mausmodelle eine Schlüsselrolle für T bet in der Regulation der ILC-Differenzierung und der Entstehung von Lymphknoten. Die zusätzliche genetische Ablation von T-bet in RORgt-defizienten Mäusen beeinflusste Differenzierungsentscheidungen in fötalen ILCP und ermöglichte die Akkumulation von ILCP mit LTi-Aktivität, wodurch die Organogenese von Lymphknoten, unabhängig von RORgt wiederhergestellt wurde. PLZF+ ILCP von RORgt/T-bet-Doppeldefizienten Mäusen bestanden bis ins Erwachsenenalter, wo diese Zellen die Darmbarrierefunktionen durch Produktion von IL-22 wiederherstellten. Darüber hinaus erwies sich RORa als entscheidend für die Entwicklung von PLZF+ ILCP und die damit verbundene Bildung von Lymphknoten. / Innate lymphoid cells (ILCs) represent a family of innate effector cells lacking rearranged antigen receptors, which are classified into three main groups based on their lineage-specifying transcription factors (TF) and effector functions. During embryonic development, the formation of lymphoid organs critically relies on a specific member of group 3 innate lymphoid cells (ILC3), expressing the master transcription factor RORgt and exhibiting lymphoid tissue inducer (LTi) functions. Accordingly, RORgt-deficient mice lack ILC3 and do not generate lymph nodes (LN). While it is established that T-bet is co-expressed with RORgt in a subset of ILC3 emerging postnatally and influencing their differentiation, phenotype and functions, the effect of T-bet on fetal ILC3 biology and its impact on LN generation remains completely unknown. In order to study the role of T-bet in fetal ILC3 differentiation and functions as well as in LN formation, single-cell RNA sequencing and flow cytometry were applied to characterize fetal ILC subsets revealing an unanticipated heterogeneity within embryonic ILC3 and identifying T-bet+ ILC3 subsets within the fetal intestine and mesenteric LN anlage for the first time. Furthermore, PLZF+ ILC progenitors (ILCP) were exposed in the developing mouse intestine. Importantly, using multiple mouse models, a key role for T-bet in regulating ILC differentiation and LN formation was discovered. Specifically, additional deficiency of T-bet in RORgt-deficient mice skewed lineage fate decisions in differentiating fetal ILCP and allowed accumulation of ILCP with LTi activity, thereby rescuing LN organogenesis in a RORgt-independent fashion. PLZF+ ILCP of RORgt/T-bet double deficient mice persisted into adulthood where these cells restored intestinal barrier functions through reinstalled IL-22 production. Moreover, RORa was found to be critical for the development of PLZF+ ILCP and associated LN formation.

This study utilized hedonic pricing models and regression analysis to evaluate if, and to whatextent distance to certain logistics nodes impact the transactional value of warehouses andlogistics properties. The study is conducted in Sweden, using data collected from transactionsthat have been conducted in the three largest cities in Sweden between the years 2016 - 2022.The logistical nodes that are tested within the study are the biggest seaports, airports andhighways in the big city regions. Furthermore, the distances to the central business districts ineach respective city are included in the analysis as well. The distances are collected bymeasuring the shortest road travel routes using Google Maps. Aside from the aforementionedlocational attributes that were tested, physical variables and dummy variables were includedin the model to investigate their effect on the transaction value of the logistics properties.Furthermore, these were included to prove the robustness of the proposed models. The results from the study indicate that all the logistical nodes tested are significant for thevalue of the industrial properties. Proximity to seaport, central business district and highwayshave a negative gradient, indicating a higher value of the logistics properties if in proximityto these nodes. While the distance to the airport is significant for the value of the logisticsproperties, the proximity to the airport does not induce a higher transaction value. The studyconcluded that the distance to seaport had an effect of -0,50%, CBD -0,83%, Highway-0,62% and Airport 0,47% per kilometer of change. This study aims to contribute to theexpanding literature on the topic of optimal warehouse location and to inform propertyowners of what attributes to consider when constructing logistic properties. / Denna studie använder hedoniska prismodeller och regressionsanalys för att utvärdera om,och i vilken utsträckning avstånd till logistiknoderna hamn, flygplats och motorväg påverkartransaktionsvärdet för lager och logistikfastigheter. Studien genomfördes i Sverige med hjälpav data insamlad från transaktioner som har genomförts i de tre största städerna i Sverigemellan åren 2016 - 2022. Transaktionsdatan samlades in genom Datscha. Vidare utreds ävenhuruvida avstånd till central business districts har en inverkan på transaktionspriset.Avstånden mäts genom att mäta de kortaste transportsträckorna mellan fastighet och nod.Avstånden i fråga har samlats in med hjälp av Google Maps. Resultaten från studien tyder påatt alla logistiknoder som testats har betydelse för fastighetens värde. Närhet till hamn, CBDoch motorvägar har en negativ koefficient, vilket indikerar ett högre transaktionsvärde påfastigheten i de fall de är belägna i närheten dessa noder. Avståndet till flygplatsen har ocksåbetydelse för värdet på fastigheterna. Denna variabel har dock en positiv koefficient, vilketindikerar att närhet till denna logistiknod har en negativ inverkan på transaktionspriset.Slutsatsen från analysen indikerar att avståndet till hamn hade en effekt på -0,50%, CBD-0,83%, motorväg -0,62% och flygplats 0,47% per kilometer av förändring. Denna studiesyftar till att bidra till den växande litteraturen om ämnet optimal lagerlokalisering och attinformera fastighetsägare om vilka attribut som ska beaktas när de bygger logistikfastigheter.

For structural engineers, the two most important design criteria are utility andsafety. It is about making sure that a structural component is reliable enough not toendanger any of a building's users, while at the same time being as sustainable andefficiently designed as possible. In other words, an element must be safe enough towithstand the improbability and sufficiently cheap to be relevant for the design.Considering this, using a material such as wood instead of metal may prove to be asustainable alternative for certain building components.Timber can be designed to sustain high temperatures and fire; it has a high strengthrelative to its weight and is naturally produced. Furthermore, an engineered woodproduct such as birch plywood has proven very strong in structural applications,especially when glued. Therefore, birch plywood has great potential as a reliablematerial in structural components. In this work, a total of 24 specimens with birchplywood connections were tested experimentally.The specimens were designed to enforce stress states that would occur in actualtrusses. Additionally, Specimens were assembled with two different connectionmethods, one being a dowel-type connection and the other being a glued-type. Eachtype of connection was tested in both tension and compression, with a total of threerepetitions each. For the glued-type specimens, birch plywood plates wereinvestigated in three different angles to the face grain; 0°, 5° and 15°. Theload-displacement relationships and the failure modes are of specific interest in thisthesis.Test results showed that failure modes were semi-brittle and distinct, and the testsshowed that glued-type connections withstood 37% higher loads than dowelledtypes. Specimens might withstand even higher loads if gluing were performed in amore controlled environment. The load-to-face-grain angle of plywood also had asignificant impact on the capacity of connections. For the 0°-specimens with gluedconnections tested in compression, no failures occurred in the plywood, and testsreached loads as high as 82 kN. Calculations were made estimating the load capacityas high as 95 kN, but possibly a more realistic approximation would be 85 kN. Thiswould imply that the 0°-specimens are around 20% stronger than the 15°-specimensand approximately 17,7% stronger than the 5°-specimens tested in compression.Birch plywood is promising to be used in connections of timber structures whereplates transfer forces between structural elements.

Hardware-software co-design techniques are very suitable to develop the next generation of sensornet applications, which have high computational demands. By making use of a low power FPGA, the peak computational performance of a sensor node can be improved without significant degradation of the standby power dissipation. In this contribution, we present a methodology and tool to enable hardware/software co-design for sensor node application development. We present the integration of nesC, a sensornet programming language, with GEZEL, an easy-to-use hardware description language. We describe the hardware/software interface at different levels of abstraction: at the level of the design language, at the level of the co-simulator, and in the hardware implementation. We use a layered, uniform approach that is particularly suited to deal with the heterogeneous interfaces typically found on small embedded processors. We illustrate the strengths of our approach by means of a prototype application: the integration of a hardware-accelerated crypto-application in a nesC application. / Master of Science