Under de senaste årtiondena har planeten, på grund av människans överanvändning av resurser, genomgått stora klimatförändringar och global uppvärmning. Den prognostiserade ökningen av population i kombination med den urbanisering som pågått de senaste 40 åren där fler söker sig till storstäderna kommer att resultera i ett ökat bostadsbyggande. Detta i sig innebär stora utmaningar då byggsektorn idag står för en betydande del av samhällets klimatpåverkan ur ett livscykelperspektiv. En del av byggsektorns negativa klimatpåverkan kommer från dess ohållbara avfallshantering där en stor mängd av det avfall som slängs är potentiellt återanvändbart material. Med anledning av detta har syftet med denna studie varit att undersöka huruvida omvänd logistik, inriktat mot återbruk, i samverkan mellan byggentreprenörer i begränsade tätbebyggda stadsområden kan reducera avfall av byggmaterial för en mer hållbar utveckling. Det teoretiska ramverk som identifierats i studien, och ligger till grund för resultatet och de slutsatser som dragits, består främst av tre teorier: hållbar utveckling, cirkulär ekonomi och omvänd logistik. Hållbar utveckling med sina tre underdimensioner: social, ekologisk och ekonomisk hållbarhet syftar huvudsakligen till det optimala läge där jordens resurser förbrukas på ett så hållbart sätt som möjligt. Cirkulär ekonomi är en process där ett använt material används så länge som möjligt i ett cirkulärt kretslopp med möjligheten att organisera och optimera hållbara materialflöden genom att bevara resurser och minska avfall. Slutligen är omvänd logistik en gren inom logistiken som syftar till hur en produkt av något slag hanteras, efter att den sålts och använts, med en effektiv hantering som antingen skapar nytt värde eller korrekt bortskaffande. Empirin är framtagen utifrån en kvalitativ metod i form av intervjuer kompletterat med kvantitativa data från en enkät. Resultatet bekräftar det som utgör studiens problem att det slängs brukbart material varpå ett medelvärde på åtta procent av det totala avfallet enligt studien har uppskattats vara brukbart. De materialen med störst potential till återanvändning är virke, skivmaterial av olika slag, isolering, armering och stålreglar. Gällande studiens inriktning att öka återanvändandet i samverkan mellan byggentreprenörer så finns det en generellt positiv inställning till det. Det finns även en insikt i att det genom samverkan kan vara möjligt att lösa problemet med dagens ohållbara avfallshantering under förutsättningen att de utmaningar som identifierats kan lösas. De största utmaningar som identifierats i studien var främst problematik med lagerhållning, kvalitetssäkring av återanvändningsbart material och resursineffektivitet. I studien har det framkommit att för att kunna påbörja återanvändning i samverkan för alla typer av byggmaterial finns det faktorer som måste lösas vilket innebär att det inte är något som kan implementeras idag. Däremot finns det inga egentliga större hinder till att börja återanvända standardiserat byggmaterial till provisorier då kvalitetsäkringsfrågan i form av garanti inte är relevant samt att det finns ett behov av sådant material under hela byggprocessen vilket löser problematiken med lagerhållning. För att påbörja arbetet med detta skulle digitala plattformar som idag redan finns kunna användas som marknadsplats, där det läggs in en begräsning på vilka som får köpa materialet som då skulle vara närliggande projekt. Även en enkel utgångpunkt istället för en digital plattform vore att en tätare kommunikation hålls mellan projekten och att materialfrågan därmed kan hanteras på samverkansmöten som hålls en gång i veckan. Slutligen kan det utifrån detta konstateras att efter en tids implementering av den här typen av omvänd logistik, inriktat mot återanvändning i samverkan, bör mängden avfall kunna reduceras jämfört med idag. Det skapar en mer cirkulär ekonomi i de begränsade tätbebyggda stadsområdena vilket i sin tur bidrar till en mer hållbar utveckling. / In the past decades the planet has, due to human overuse of resources, undergone climate change and global warming. Because of the projected increase of the population as well as the urbanization that has been going on the last 40 years, where more people seek towards metropolitan areas, it will result in an increased construction of housing. This will result in challenges considering the fact that the construction sector today represents a significant part of society's negative climate impact from a life-cycle perspective. One factor contributing to the negative climate effect given by the construction industry is its unsustainable waste management in which a significant part of the wasted materials is reusable. For this reason, the purpose of this research has been to investigate whether reverse logistics, targeted at reuse of construction materials, in collaboration between contractors in limited urban areas can reduce waste materials for sustainable development. The theoretical framework identified in this study, from which the result obtained originates and the conclusions are drawn, consists primarily of three theories: sustainable development, circular economy and reverse logistics. Sustainable development with its three dimensions: social, ecological and economic sustainability is aimed to reach the optimal stage in which resources are consumed in a sustainable way as possible. Circular economy is a process where used material is used as long as possible in a circular cycle with the ability to organize and optimize sustainable material flows, this by conserving resources and reducing waste. Lastly, reverse logistics is a branch within the common logistics that manage products of any kind after usage with an efficient management that either creates new value or a proper disposal. The results are based on a qualitative method with interviews supplemented by quantitative data from a questionnaire. The results confirm what constitutes the study's problem of today's unsustainable waste management in which still usable materials are discarded, whereupon the mean value of eight percent of the total waste is estimated to still be usable. The materials with the greatest potential for reuse are wood, board materials of various kinds, insulation, reinforcement bars and steel joists. Regarding the study's focus on increasing reuse in collaboration between contractors, a general positive attitude is seen towards it and there is an insight in the fact that solving the problem of today's unsustainable waste management will be difficult without collaboration. However, this is given by the fact that the challenges identified can be solved. The identified challenges in the study were mainly problems with quality assurance on reusable materials, inventory and resource inefficiency. In this study it has emerged that when it comes to starting reuse in collaboration consisting all types of building materials, there are factors that must be resolved before it will be possible. Something that stands in the way of implementing it today. On the other hand, there are no major obstacles towards reusing standardized building materials for temporary work since the quality assurance issue in the form of a guarantee is not relevant and that there is a need for such material during the entire building process, which solves the problem of inventory. To begin work on this, digital platforms that already exist today could be used as a marketplace, where a restriction is placed on who may buy the material. It could also be as simple as keeping a closer communication between projects. Finally it can be concluded that, after a period of time, an implementation of this type of reverse logistics, focused on reuse in collaboration, will be able to reduce the amount of waste compared to today. This will create a more circular economy in limited urban areas, whilst contributing to a more sustainable development.

No description available.

No / Nanoscale reversed-phase liquid chromatography (LC) combined with electrospray ionization-tandem mass spectrometry (ESI-MS/MS) has been used as a method for the direct identification of multiple cytochrome P450 (P450) isoforms found in male and female rat liver. In this targeted proteomic approach, rat liver microsomes were subjected to sodium dodecyl sulfate-polyacrylamide gel electrophoresis followed by in-gel tryptic digestion of the proteins present in the 48- to 62-kDa bands. The resultant peptides were extracted and analyzed by LC-ESI-MS/MS. P450 identifications were made by searching the MS/MS data against a rat protein database containing 21,576 entries including 47 P450s using Sequest software (Thermo Electron, Hemel Hempstead, UK). Twenty-four P450 isoforms from the subfamilies 1A, 2A, 2B, 2C, 2D, 2E, 3A, 4A, 4F, CYP17, and CYP19 were positively identified in rat liver.

No / Surfactants are commonly used as cleansing agents and yet there are concerns that they may also have a role in skin irritation. The lack of suitable methods for the quantitative and qualitative analysis of surfactant deposition on skin has hindered the in-depth investigation of such effects. Here, we report the application of reversed-phase liquid chromatography/electrospray ionisation tandem mass spectrometry (LC/ESI-MS/MS) assays for two surfactants commonly used in consumer products, namely sodium lauryl ether sulfate (SLES) and laurylamidopropyl betaine (LAPB), to a baseline study aiming to assess deposition levels on human skin. The linearity of the assays was established at 3-20 ng, with coefficient of variation below 5%. The detection limits were 100 pg for LAPB and 1 ng for SLES; quantitation limits were 500 pg for LAPB and 2.5 ng for SLES. The baseline study was conducted using a panel of 40 healthy volunteers. Skin extract samples were taken in triplicate from forearms, using ethanol. SLES was detected on most volunteers, with 75% of them having SLES deposits in the range of 100-600 ng/cm(2). LAPB was detected on the skin of all volunteers with 85% of them having deposit levels within the concentration range of 1-100 ng/cm(2). These results demonstrate the extent to which commonly used surfactants remain on the skin during the day. The analytical methods reported here can be applied to the investigation of surfactants in relation to general skin condition and to the development and optimisation of new consumer wash products. / EPSRC-DTA award / School Life Sciences

Textilindustrin präglas av en snabb produktionstakt som genererar stora mängder textilavfall. År 2025 träder Avfallsdirektivet bestämmelser om separat textilinsamling i kraft, vilket innebär att den svenska avfallsindustrin står inför en stor omställning. Studien syftar därför till att utforska aktörernas ansvarsområden och positioner inom textil avfallshantering. För att kunna öka förståelsen för hur nya direktiv kan implementeras på ett effektivt sätt belyser studien även utmaningar och möjligheter. Målet är således att främja övergången till en cirkulär ekonomi och förbättrad avfallshantering i Sverige. För att samla in data har en kvalitativ metod tillämpats, där fyra semistrukturerade intervjuer med relevanta aktörer verksamma inom den textila värdekedjan genomfördes. Empirin analyserades genom en tematisk analys som resulterade i tre huvudteman och åtta tillhörande subteman. Studien visar på en omogen marknad som möts av utmaningar i form av otillräckliga volymer, bristande infrastruktur och konsumenters okunskap. Det finns dock möjligheter som ponerar ett samordnat avfallssamhälle med medvetna konsumenter där avfall ses som resurs. Studien bidrar således med kunskap inom den svenska avfallshanteringens omställningsarbete mot en cirkulär ekonomi. / The textile industry is characterized by a rapid production pace that generates large amounts of textile waste. In 2025, the Waste Directive’s regulation on separate textile collecting will come into force, which means that the Swedish waste industry is facing a major transition. Therefore, this study aims to explore the responsibilities and positions of actors within textile waste management. To increase understanding of how new directives can be implemented effectively, this study also highlights challenges and opportunities. The goal is therefore to promote the transition to a circular economy and improved waste management in Sweden. For data collection, a qualitative method has been applied, where four semi-structured interviews with relevant actors involved in the textile value chain were conducted. The empirical data was analyzed through thematic analysis, resulting in three main themes with eight belonging subthemes. The study reveals an immature market facing challenges such as insufficient volumes, inadequate infrastructure and consumer ignorance. However, there are opportunities that suggest a coordinated waste society with informed consumers where waste is seen as a resource. The study therefore contributes with knowledge to the Swedish waste management’s transition towards a circular economy.

Dans ce mémoire, nous étudions le problème de l'estimation de la variance pour les estimateurs par double dilatation et de calage pour l'échantillonnage à deux phases. Nous proposons d'utiliser une décomposition de la variance différente de celle habituellement utilisée dans l'échantillonnage à deux phases, ce qui mène à un estimateur de la variance simplifié. Nous étudions les conditions sous lesquelles les estimateurs simplifiés de la variance sont valides. Pour ce faire, nous considérons les cas particuliers suivants : (1) plan de Poisson à la deuxième phase, (2) plan à deux degrés, (3) plan aléatoire simple sans remise aux deux phases, (4) plan aléatoire simple sans remise à la deuxième phase. Nous montrons qu'une condition cruciale pour la validité des estimateurs simplifiés sous les plans (1) et (2) consiste à ce que la fraction de sondage utilisée pour la première phase soit négligeable (ou petite). Nous montrons sous les plans (3) et (4) que, pour certains estimateurs de calage, l'estimateur simplifié de la variance est valide lorsque la fraction de sondage à la première phase est petite en autant que la taille échantillonnale soit suffisamment grande. De plus, nous montrons que les estimateurs simplifiés de la variance peuvent être obtenus de manière alternative en utilisant l'approche renversée (Fay, 1991 et Shao et Steel, 1999). Finalement, nous effectuons des études par simulation dans le but d'appuyer les résultats théoriques. / In this thesis we study the problem of variance estimation for the double expansion estimator and the calibration estimators in the case of two-phase designs. We suggest to use a variance decomposition different from the one usually used in two-phase sampling, which leads to a simplified variance estimator. We look for the necessary conditions for the simplified variance estimators to be appropriate. In order to do so, we consider the following particular cases : (1) Poisson design at the second phase, (2) two-stage design, (3) simple random sampling at each phase, (4) simple random sampling at the second phase. We show that a crucial condition for the simplified variance estimator to be valid in cases (1) and (2) is that the first phase sampling fraction must be negligible (or small). We also show in cases (3) and (4) that the simplified variance estimator can be used with some calibration estimators when the first phase sampling fraction is negligible and the population size is large enough. Furthermore, we show that the simplified estimators can be obtained in an alternative way using the reversed approach (Fay, 1991 and Shao and Steel, 1999). Finally, we conduct some simulation studies in order to validate the theoretical results.

Foram desenvolvidas metodologias de cromatografia a líquido de fase reversa baseadas em injeção sequencial (SIC) e em cromatografia a líquido de alta eficiência (HPLC) para determinação de triclosan em amostras de produtos de higiene pessoal e em estudos de adsorção em argilominerais naturais e modificados, visando determinar parâmetros de adsorção de triclosan frente a alguns de seus metabólitos. A determinação de triclosan em enxaguadores bucais foi realizada por SIC com eluição isocrática usando fase móvel constituída por acetonitrila: tampão fosfato de trietilamina 70 mM pH 3,5 na proporção 70:30 (v v-1), obtendo-se limites de detecção e de quantificação de 0,22 e 0,72 mg L-1, respectivamente. Taxas de recuperação entre 96 e 98% foram obtidas da aplicação a amostras reais, sendo que os resultados obtidos pelo método proposto não apresentaram evidências de diferenças estatisticamente significativas em comparação a uma metodologia de referência baseada em HPLC com coluna empacotada. A separação de triclosan (TCS), 2-clorofenol (2-CP), 2,4-diclorofenol (2,4-DCP), 2,4,6-triclorofenol (2,4,6-TCP), 2,3,4-triclorofenol (2,3,4-TCP) e metiltriclosan (MTCS) foi estudada por SIC, obtendo-se a separação de TCS, 2-CP, 2,4-DCP e 2,4,6-TCP com duas etapas de eluição isocrática, a primeira delas com fase móvel 60:40 (v v-1) metanol: tampão acetato de amônio 20 mM (pH 5,5) seguida de eluição com fase móvel 70:30 (v v-1) metanol : tampão acetato de amônio 20 mM (pH 5,5). Nesse caso, os isômeros 2,4,6-TCP e 2,3,4-TCP coeluem. Metiltriclosan, o menos polar desses compostos, pode ser separado de TCS com etapas subseqüentes de eluição. Os métodos foram aplicados para estudar a adsorção de triclosan e seus metabólitos 2,4-DCP, 2,4,6-TCP e metiltriclosan em montmorilonita homoiônica (K+) e modificada com sal de hexadeciltrimetilamônio (HDTMA), observando-se forte adsorção de triclosan e metiltriclosan em comparação a 2-CP, 2,4-DCP e 2,4,6-TCP. A incorporação de HDTMA no argilomineral causou significativo aumento da capacidade de adsorção desses metabólitos, determinada a partir do ajuste dos dados experimentais à equação linearizada de Langmuir, observando-se que a ordem de adsorção é 2,4,6-TCP > 2,4-DCP > 2-CP / Reversed-phase liquid chromatography methodologies based on sequential injection (SIC) and high performance liquid chromatography (HPLC) have been developed for determination of triclosan in samples of personal hygiene products and in studies of adsorption on natural and modified clay minerals aiming to determine kinetic and thermodynamic parameters of adsorption of triclosan in comparison with some of its metabolites. The determination of triclosan in oral rinses with SIC was performed by isocratic elution using a mobile phase of acetonitrile : 70 mM triethylamine phosphate buffer pH 3.5 at the ratio 70:30 (v v-1), obtaining limits of detection and quantification of 0.22 and 0.72 mg L-1, respectively. Recovery rates between 96 and 98 % were obtained from the application to commercial samples, and the results obtained by the proposed method showed no evidence of statistically significant differences compared to the reference methodology based on HPLC with packed column. The separation of triclosan (TCS), 2-chlorophenol (2-CP), 2,4-dichlorophenol (2,4-DCP), 2,4,6-trichlorophenol (2,4,6-TCP), 2,3,4 trichlorophenol (2,3,4-TCP) and methyltriclosan (MTCS) was studied by SIC, resulting in the separation of TCS, 2-CP, 2,4-DCP and 2,4,6-TCP with two isocratic elution steps, the first of them with a mobile phase 60:40 (v v-1) methanol: 20 mM ammonium acetate buffer (pH 5.5) followed by elution with 70:30 (v v-1) mobile phase of methanol : 20 mM ammonium acetate buffer (pH 5.5). In this case, the isomers 2,4,6-TCP and 2,3,4-TCP coeluted. Methyltriclosan, the less polar of these compounds, can be separated from TCS with subsequent elution steps. The methods were applied to study the adsorption of triclosan and its metabolites 2-CP, 2,4-DCP, 2,4,6-TCP and methyltriclosan on homoionic montmorillonite (K+) as well as in hexadecyltrimethylammonium salt (HDTMA) modified montmorillonite, noticing a stronger adsorption of triclosan and methyltriclosan compared with 2-CP, 2,4-DCP and 2,4,6-TCP. Incorporation of HDTMA in the clay mineral caused significant increase in adsorption capacity of these metabolites. This capacity was determined by fitting the experimental data to the linearized Langmuir equation. The adsorption order was 2,4,6-TCP > 2,4-DCP > 2-CP.

Dans ce mémoire, nous étudions le problème de l'estimation de la variance pour les estimateurs par double dilatation et de calage pour l'échantillonnage à deux phases. Nous proposons d'utiliser une décomposition de la variance différente de celle habituellement utilisée dans l'échantillonnage à deux phases, ce qui mène à un estimateur de la variance simplifié. Nous étudions les conditions sous lesquelles les estimateurs simplifiés de la variance sont valides. Pour ce faire, nous considérons les cas particuliers suivants : (1) plan de Poisson à la deuxième phase, (2) plan à deux degrés, (3) plan aléatoire simple sans remise aux deux phases, (4) plan aléatoire simple sans remise à la deuxième phase. Nous montrons qu'une condition cruciale pour la validité des estimateurs simplifiés sous les plans (1) et (2) consiste à ce que la fraction de sondage utilisée pour la première phase soit négligeable (ou petite). Nous montrons sous les plans (3) et (4) que, pour certains estimateurs de calage, l'estimateur simplifié de la variance est valide lorsque la fraction de sondage à la première phase est petite en autant que la taille échantillonnale soit suffisamment grande. De plus, nous montrons que les estimateurs simplifiés de la variance peuvent être obtenus de manière alternative en utilisant l'approche renversée (Fay, 1991 et Shao et Steel, 1999). Finalement, nous effectuons des études par simulation dans le but d'appuyer les résultats théoriques. / In this thesis we study the problem of variance estimation for the double expansion estimator and the calibration estimators in the case of two-phase designs. We suggest to use a variance decomposition different from the one usually used in two-phase sampling, which leads to a simplified variance estimator. We look for the necessary conditions for the simplified variance estimators to be appropriate. In order to do so, we consider the following particular cases : (1) Poisson design at the second phase, (2) two-stage design, (3) simple random sampling at each phase, (4) simple random sampling at the second phase. We show that a crucial condition for the simplified variance estimator to be valid in cases (1) and (2) is that the first phase sampling fraction must be negligible (or small). We also show in cases (3) and (4) that the simplified variance estimator can be used with some calibration estimators when the first phase sampling fraction is negligible and the population size is large enough. Furthermore, we show that the simplified estimators can be obtained in an alternative way using the reversed approach (Fay, 1991 and Shao and Steel, 1999). Finally, we conduct some simulation studies in order to validate the theoretical results.

Žlugus Sovietų Sąjungai vienas milijonas rusakalbių atvyko į Izraelį iš buvusių komunistinių šalių. Šiandien 20 % Izraelio visuomenės sudaro rusakalbiai asmenys. Iš kitų visuomenės grupių jie išsiskiria tuo, kad nesugebėjo tapti integralia Izraelio visuomenės dalimi ir sukūrė atskirą rusakalbių subkultūrą šalyje. Šis atsiskyrimas nuo likusios Izraelio visuomenės lemia sudėtingus rusakalbių žydų bendruomenės tarpusavio santykius su Izraeliu ir Rusija: Izraelio politiniame ir ekonominiame gyvenime ji dalyvauja tarytum „atskira etninė grupė“, o su Rusija sukuria stiprų diasporinį ryšį. Žlugus Sovietų Sąjungai ne tik milijonas rusakalbių žydų sugrįžo į savo tėvynę, bet ir Rusija su Izraeliu užmezgė ir ėmė vystyti draugiškus santykius. Darbe keliamas tikslas išsiaiškinti, kokį vaidmenį rusakalbių Izraelio žydų bendruomenė vaidina Izraelio-Rusijos tarpusavio santykiuose. Atsižvelgiant į darbo tikslą, keliama hipotezė: rusakalbių Izraelio žydų bendruomenė yra vienas iš Rusijos-Izraelio santykių transformaciją teigiama kryptimi lėmusių veiksnių. Siekiant patikrinti hipotezę, numatomi tokie uždaviniai: 1) apsibrėžti diasporos sąvoką ir teorinį diasporos veikimo tarp gimtosios ir priimančiosios valstybių modelį; 2) išsiaiškinti rusakalbių žydų bendruomenės identifikavimosi su rusiškąja kultūra ypatumus ir įvertinti šios identifikacijos sąlygojamą nesiintegravimo į Izraelio visuomenę procesą; 3) įvertinti rusakalbių žydų bendruomenės, Izraelio ir Rusijos interesus viena kitos atžvilgiu... [toliau žr. visą tekstą] / Since the demise of FSU, about one million Russian speakers from all republics of the FSU have moved to Israel. Today Russian Jews amount to 20 % of Israeli society. This aliyah doesn’t integrate into Israeli society and forms Russian speakers’ subculture (externalized through particular cultural identity, Russian language community formation and no integration process) in Israel. This segregation determines complex Russian Jews relationship with Israel and Russia: in Israel this community functions like separate ethnic group and creates diasporic ties with Russia. As a result of the demise of the FSU Russia-Israel relations take a new form. Russia renounced it’s entirely proarabic politics and started developing friendly ties with Israel. The aim of the work is to determine the role of Israeli Russian Jews community in Israel-Russia relations, keeping in mind that Israeli Russian speakers in Israel society act like the separate ethnic group with strong diasporic ties with Russia. The hypothesis of the work – Israeli Russian Jews community is one of the factors, affecting Israel-Russia relations transformation in positive way. In order to verify the hypothesis there are formed four goals: 1) to define the term „diaspora“and theoretical model of diaspora‘s action between hostland and homeland; 2) to analyze Israeli Russian Jews community‘s identification with Russian culture and evaluate the disintegration into Israeli society process; 3) to evaluate Israel, Russia and... [to full text]

In this study, a reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed to separate and determine Pt and Pd after formation of their chelates with N,N-diethyl-N&#039 / -benzoylthiourea (DEBT). With the aim of reducing the number of steps in treating the samples, the method developed does not require the elimination of excess chelating reagent before the analysis of metal chelates. The different physical and chemical parameters affecting separation were examined in details. The whole analysis was completed on a C18 column in 16 min at 280 nm, with the mobile phase of acetonitrile-methanol-water (80:10:10, v:v:v) containing 0.20 mol l-1 pH 5.0 acetate buffer at a flow rate of 0.8 ml min-1. Detection limits of the method, based on 3s, were found as 14.2 ug l-1 for Pd and 0.77 mg l-1 for Pt using a 20-ul sample loop. Reproducibility of the method for ten repeated measurements was found as 2.36 % for 0.60 mg l-1 Pd and 2.58 % for 10.0 mg l-1 Pt as % RSD. The proposed method is a rapid, simple and highly selective method for the simultaneous determination of Pt and Pd by HPLC without the need for any interference elimination process.