<p>Social phobia is a disabling, lifelong disorder characterised by fear in social settings.</p><p>The aim of the present study was to gain more knowledge about diagnostic, neurobiologic and epidemiologic aspects of social phobia.</p><p>Thirty-two individuals were assessed by the Structured Clinical Interview for DSM-IV Axis I and II psychiatric disorders, the Karolinska Scales of Personality and the Temperament and Character Inventory. Social phobia was accompanied by concurrent axis I disorders in about 28% of individuals, lifetime axis I disorders in 54%, personality disorders in 60%, and avoidant personality disorder (APD) in 47%. This suggests that there is a high comorbidity between social phobia and APD according to the DSM-IV criteria. The personality profiles associated with social phobia were dominated by anxiety-related traits that were primarily related to social phobia itself and not to the presence of concurrent personality disorders.</p><p>Eighteen subjects with social phobia and eighteen controls were investigated with positron emission tomography and the radiolabeled serotonin precursor, [3 -11C]–5-HTP (5-HTP). Individuals with social phobia demonstrated proportionally lower regional relative whole brain accumulation of 5-HTP in areas of the frontal and temporal cortices as well as the striatum, but higher accumulation in the cerebellum. This suggests that there are imbalances in presynaptic serotonin function in individuals with social phobia, although this could only be confirmed in men, and not in women.</p><p>By means of a postal survey, distributed to 2000 randomly selected individuals, social phobia in Sweden was found to be common, with a point prevalence of 15.6%.</p>

<p>Social phobia is a disabling anxiety disorder characterized by an excessive fear of negative evaluation in social situations. The present thesis explored the epidemiology and neurobiology of the disorder. By means of a mailed questionnaire, the point prevalence of social phobia in the Swedish general population was estimated at 15.6%. However, prevalence rates varied between 1.9 and 20.4% across the different levels of distress and impairment used to define cases. Thus, although social anxiety is widespread within the community, the precise diagnostic boundaries for social phobia are difficult to determine. Social phobia was associated with female gender, low educational attainment, psychoactive medication use, and lack of social support. A cluster analysis revealed that subtypes of social phobia mainly differed dimensionally on a mild-moderate-severe continuum, with number of cases declining with increasing severity. Public speaking was the most common social fear in all groups of social phobics and in the population at large.</p><p>In the neurobiological studies, positron emission tomography was used to examine brain serotonin metabolism and changes in the regional cerebral blood flow (rCBF) response to public speaking stress following treatment with a selective serotonin reuptake inhibitor (SSRI) or cognitive-behavioral group therapy. Social phobics exhibited lowered serotonin turnover, relative to non-phobics, mainly in the medial temporal cortex including the bilateral rhinal and periamygdaloid regions. Symptom improvement with cognitive-behavioral- as well as SSRI-treatment was accompanied by a reduced rCBF-response to public speaking in the amygdala, hippocampus and adjacent temporal cortex, i.e. regions that serve important functions in anxiety. Thorough suppression of rCBF in limbic brain regions was associated with favorable long-term treatment outcome. These results provide neuroimaging evidence for a presynaptic serotonergic dysfunction in social phobia and for a common neural mechanism whereby psychological and pharmacological anti-anxiety treatments act.</p>

Social phobia is a disabling anxiety disorder characterized by an excessive fear of negative evaluation in social situations. The present thesis explored the epidemiology and neurobiology of the disorder. By means of a mailed questionnaire, the point prevalence of social phobia in the Swedish general population was estimated at 15.6%. However, prevalence rates varied between 1.9 and 20.4% across the different levels of distress and impairment used to define cases. Thus, although social anxiety is widespread within the community, the precise diagnostic boundaries for social phobia are difficult to determine. Social phobia was associated with female gender, low educational attainment, psychoactive medication use, and lack of social support. A cluster analysis revealed that subtypes of social phobia mainly differed dimensionally on a mild-moderate-severe continuum, with number of cases declining with increasing severity. Public speaking was the most common social fear in all groups of social phobics and in the population at large. In the neurobiological studies, positron emission tomography was used to examine brain serotonin metabolism and changes in the regional cerebral blood flow (rCBF) response to public speaking stress following treatment with a selective serotonin reuptake inhibitor (SSRI) or cognitive-behavioral group therapy. Social phobics exhibited lowered serotonin turnover, relative to non-phobics, mainly in the medial temporal cortex including the bilateral rhinal and periamygdaloid regions. Symptom improvement with cognitive-behavioral- as well as SSRI-treatment was accompanied by a reduced rCBF-response to public speaking in the amygdala, hippocampus and adjacent temporal cortex, i.e. regions that serve important functions in anxiety. Thorough suppression of rCBF in limbic brain regions was associated with favorable long-term treatment outcome. These results provide neuroimaging evidence for a presynaptic serotonergic dysfunction in social phobia and for a common neural mechanism whereby psychological and pharmacological anti-anxiety treatments act.

Social phobia is a disabling, lifelong disorder characterised by fear in social settings. The aim of the present study was to gain more knowledge about diagnostic, neurobiologic and epidemiologic aspects of social phobia. Thirty-two individuals were assessed by the Structured Clinical Interview for DSM-IV Axis I and II psychiatric disorders, the Karolinska Scales of Personality and the Temperament and Character Inventory. Social phobia was accompanied by concurrent axis I disorders in about 28% of individuals, lifetime axis I disorders in 54%, personality disorders in 60%, and avoidant personality disorder (APD) in 47%. This suggests that there is a high comorbidity between social phobia and APD according to the DSM-IV criteria. The personality profiles associated with social phobia were dominated by anxiety-related traits that were primarily related to social phobia itself and not to the presence of concurrent personality disorders. Eighteen subjects with social phobia and eighteen controls were investigated with positron emission tomography and the radiolabeled serotonin precursor, [3 -11C]–5-HTP (5-HTP). Individuals with social phobia demonstrated proportionally lower regional relative whole brain accumulation of 5-HTP in areas of the frontal and temporal cortices as well as the striatum, but higher accumulation in the cerebellum. This suggests that there are imbalances in presynaptic serotonin function in individuals with social phobia, although this could only be confirmed in men, and not in women. By means of a postal survey, distributed to 2000 randomly selected individuals, social phobia in Sweden was found to be common, with a point prevalence of 15.6%.

Social phobia is a common disorder associated with significant psychosocial impairment, representing a substantial public health problem largely determined by the high prevalence, and the lifelong chronicity. Social phobia starts in early childhood or adolescence and is often comorbid with depression, other anxiety disorders, alcohol and substance abuse or eating disorders. This cascade of comorbidity, usually secondary to social phobia, increases the disability associated with the condition. The possibility that social phobia may be a trigger for later developing comorbid disorders directs attention to the need for early effective treatment as a preventive measure. The most recent drug class to be investigated for the psychopharmacological treatment of social phobia is the SSRI group for which there is growing support. The other drug classes that have been evaluated are monoamine oxidase inhibitors (MAOIs), benzodiazepines, and beta-blockers. The SSRIs represent a new and attractive therapeutic choice for patients with generalized social phobia. Recently the first, large scale, placebo-controlled study to assess the efficacy of drug treatment in generalized social phobia has been completed with paroxetine. Paroxetine was more effective in reducing the symptoms than placebo and was well tolerated. Many now regard SSRIs as the drugs of choice in social phobia because of their effectiveness and because they avoid the problems of treatment with benzodiazepines or classical MAOIs.

Parental psychopathology and unfavorable family environment are established risk factors for onset of offspring social phobia (SP), but their associations with the further course, e.g., persistence of the disorder, remain understudied. A community cohort of 1395 adolescents and their parents was followed-up over almost 10 years using the DIA-X/M-CIDI. Parental diagnostic interviews were supplemented by family history data. Parental rearing was retrospectively assessed by the Questionnaire of Recalled Parental Rearing Behavior in offspring, and family functioning by the Family Assessment Device in parents. Persistence measures (proportion of years affected since onset) were derived from diagnostic interviews, using age of onset, age of recency, and course information. Lack of emotional warmth and dysfunctional family functioning characteristics were associated with higher SP persistence, particularly in interaction with parental psychopathology. Predictors for SP persistence differ from those predicting SP onset. Unfavorable family environment alone and in interaction with parental disorders predict higher SP persistence.

Objectives: For characterizing the association between parenting and offspring social phobia (SP), contrasting maternal vs. paternal contributions, putative predictors of unfavorable parenting behaviors and its specificity for SP are warranted to delineate targeted prevention and intervention strategies. Methods: A population-based sample of 1053 adolescents was followed-up using the M-CIDI. Parenting was assessed via questionnaire in offspring passing the high risk period for SP-onset. Natal complications and childhood serious health problems as assessed by maternal reports were hypothesized to relate to unfavorable parenting. Results: The pattern of maternal overprotection, paternal rejection and lower emotional warmth was associated with SP, but not with other offspring anxiety disorders. Natal complications were related to overprotection and lower emotional warmth; trend-level associations emerged for serious health problems and unfavorable parenting. Conclusions: Paternal behavior appears particularly relevant for SP. The pattern of maternal overprotection, paternal rejection and lower emotional warmth was observed in SP only, suggesting that its detailed assessment provides a promising opportunity for targeted prevention and intervention in SP.

Bakgrund: Social fobi är en sjukdom där personen har en irrationell rädsla för situationer där personen kan bli iakttagen och bedömd av andra. Rädslan kan vara så stark att det kan vara outhärdligt att vistas i samma rum som andra. Syfte: Syftet med studien var att belysa hur det är att leva med social fobi. Metod: Studien är en allmän litteraturstudie som baserades på femton kvantitativa artiklar och en självbiografisk bok. Artiklarna var publicerade efter år 1995. Enheter som svarade på syftet identifierades och sammanställdes till resultatet. Resultat: Personer med social fobi har en lägre livskvalitet. Personer med social fobi räds sociala interaktioner och anses utstråla mindre värme än andra personer. Under samtal upplever personer med social fobi ångest, de nedvärderar sitt eget uppförande då de är fokuserade på sitt eget uppträdande, vilket leder till en negativ självbild. Kognitivbeteendeterapi har visat sig vara en effektiv behandlingsmetod för att behandla social fobi. Slutsats: Livskvaliteten hos personer med social fobi är reducerad och självkänslan är ofta låg. Ångest uppstår vid social interaktion. KBT ger goda behandlingsresultat för personer med social fobi. Det är viktigt att sjukvårdspersonalen bemöter personen med social fobi på ett positivt sätt för att främja relationen. / Background: When suffering from social phobia people experience an irrational fear of being observed and judged by others. The fear can be so powerful that being in the same room with other people is unbearable. Aim: The aim of the study was to illustrate what it is like to live with social phobia. Methods: The study is a general literature study based on fifteen quantitative articles and one autobiography. Articles were published after the year of 1995. Unites responding to the aim were identified and assembled into a result. Results: Person with social phobia has a reduced quality of life. They fear social interaction and are perceived by others to emit less warmth than other people. During conversation persons with social phobia experiences anxiety, they underestimate their own performance when being excessively focused on their own behaviour. This leads to a negative self image. Cognitive behavioural therapy has shown to be an effective treatment of social phobia. Conclusion: The quality of life is reduced in social phobia and the self-esteem is often low. Social interactions result in anxiety. Cognitive behavioural therapy yields effective results for social phobia. Positive treatment from health care staff is of high relevance to promote the relationship.

published_or_final_version / Clinical Psychology / Master / Master of Social Sciences

Studien har syftat till att undersöka samband mellan samsjuklig psykologisk problematik och katastroftänkande hos ungdomar utifrån ett transdiagnostiskt perspektiv. Katastroftänkandets roll för förändring av social ångest och depressiva symtom undersöktes utifrån en studie av internetbaserad KBT-behandling mot social fobi (N=18).  Resultatet indikerar att ungdomar med hög initial nivå av katastroftänkande har större reduktion av depressiva symtom än ungdomar med låg nivå av katastroftänkande. Detta talar för att hänsyn bör tas till grad av katastroftänkande vid utformning av behandling för personer med social fobi, särskilt vid samsjuklighet med depression. Kopplingen mellan katastroftänkande och samsjuklighet undersöktes utifrån en tvärsnittsstudie av gymnasieungdomar (N=713).  Resultatet visar på en koppling mellan katastroftänkande och social rädsla, sömnproblematik och nedstämdhet. / This study was aimed at examining the relationship between co-existing psychological problems and catastrophizing in adolescents from a transdiagnostic perspective. The role of catastrophizing for the change of social anxiety and depression was analyzed in an internet based CBT-treatment for social phobia (N=18). The results indicate that adolescents with high initial level of catastrophizing have a larger reduction of depression than adolescents with low initial level of catastrophizing. This suggests that catastrophizing should be considered when specifying treatment for social phobia, especially if it co-occurs with depression. The relationship between catastrophizing and comorbidity was analyzed in a cross-sectional study of adolescents (N=713). The result suggests that catastrophizing is associated with the level of social fear, sleep problems and depression.