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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
231

Die Lösungsrechte des Versicherers bei Verletzung der vorvertraglichen Anzeigepflicht durch den Versicherungsnehmer : unter besonderer Betrachtung der Berufsunfähigkeitsversicherung /

Uhlenbrock, Inga. January 2005 (has links) (PDF)
Univ., Diss.--Köln, 2004. / Literaturverz. S. XXV - XXXVII.
232

PRECISE EVALUATION OF GNSS POSITION AND LATENCY ERRORS IN DYNAMIC AGRICULTURAL APPLICATIONS

Sama, Michael P. 01 January 2013 (has links)
A method for precisely synchronizing an external serial data stream to the pulse-per-second (PPS) output signal from a global navigation satellite-based system (GNSS) receiver was investigated. A signal timing device was designed that used a digital signal processor (DSP) with serial inputs and input captures to generate time stamps for asynchronous serial data based on an 58593.75 Hz internal timer. All temporal measurements were made directly in hardware to eliminate software latency. The resolution of the system was 17.1 µs, which translated to less than one millimeter of horizontal position error at travel speeds typical of most agricultural operations. The dynamic error of a TTS was determined using a rotary test fixture. Tests were performed at angular velocities ranging from 0 to 3.72 rad/s and a radius of 0.635 m. Average latency from the TTS was shown to be consistently near 0.252 s for all angular velocities and less variable when using a reflector based machine target versus a prism target. Sight distance from the target to the TTS was shown to have very little effect on accuracy between 4 and 30 m. The TTS was determined to be a limited as a position reference for dynamic GNSS and vehicle auto-guidance testing based on angular velocity. The dynamic error of a GNSS receiver was determined using the rotary test fixture and modeled as discrete probability density functions for varying angular velocities and filter levels. GNSS position and fixture data were recorded for angular velocities of 0.824, 1.423, 2.018, 2.618, and 3.222 rad/s at a 1 m radius. Filter levels were adjusted to four available settings including; no filter, normal filter, high filter, and max filter. Each data set contained 4 hours of continuous operation and was replicated three times. Results showed that higher angular velocities increased the variability of the distribution of error while not having a significant effect on average error. The distribution of error tended to change from normal distributions at lower angular velocities to uniform distributions at higher angular velocities. Internal filtering was shown to consistently increase dynamic error for all angular velocities.
233

Evaluation, Standardized Tests and Training Processes: Experiences in Secondary Schools in North of Mexico / Evaluación, pruebas estandarizadas y procesos formativos: experiencias en escuelas secundarias del norte de México / Evaluación, pruebas estandarizadas e procesos formativos: experiencias em escuelas secundárias do norte de México

Arzola-Franco, David Manuel 10 April 2018 (has links)
In this research, an analysis of policies and implementation processes of testinghigh school students in the State of Chihuahua, Mexico is presented. The objectiveis aimed at understanding how these practices guide or outline the dynamics ofschools, teachers and priorities of student work. The information was collectedthrough interviews, focus groups and observation records. The results indicatethat the approach that has made the assessment reinforces a school culture thatfavors the numerical results over the educational processes, competitivenessand individual success is exalted above solidarity and empathy. The evaluationapproach embodied in the curriculum and assessment practices in classrooms iscontradicted. / En esta investigación se presenta un análisis de las políticas y procesos de aplicación de pruebas a estudiantes de escuelas secundarias en el Estado de Chihuahua, México. El objetivo está encaminado a comprender de qué manera estas prácticas guían o perfilan la dinámica de las escuelas, las prioridades del profesorado y el trabajo de los estudiantes. La información se recabó a través de entrevistas, grupos de enfoque y registros de observación. Los resultados señalan que el enfoque con el que se ha realizado la evaluación refuerza una cultura escolar que privilegia los resultados numéricos sobre los procesos formativos, se exalta la competitividad y el éxito individual por encima de la solidaridad y la empatía. Se contradice el enfoque de la evaluación plasmado en el currículo y las prácticas de evaluación en los salones de clase. / Nesta pesquisa é apresentado uma análise das políticas e processos deimplementação de testes de alunos do ensino médio no Estado de Chihuahua,México. O objectivo visa a compreensão de como essas práticas orientar ou delinear a dinâmica de escolas, professores e prioridades de trabalho do aluno.As informações foram coletadas por meio de entrevistas, grupos focais e registrosde observação. Os resultados indicam que a abordagem que tem feito a avaliaçãoreforça uma cultura escolar que privilegia os resultados numéricos sobre osprocessos educativos, a competitividade eo sucesso individual é exaltado acimade solidariedade e empatia. A abordagem de avaliação incorporado nas práticascurriculares e de avaliação em salas de aula é contrariada.
234

Padrões climáticos de eventos extremos de chuva utilizando análise multivariada e de ondeletas no Estado de Minas Gerais.

SOUSA, Edicarlos Pereira de. 17 August 2018 (has links)
Submitted by Maria Medeiros (maria.dilva1@ufcg.edu.br) on 2018-08-17T14:30:53Z No. of bitstreams: 1 EDICARLOS PEREIRS DE SOUSA - TESE (PPGMet) 2016.pdf: 7117312 bytes, checksum: 96b3ee401a9f1387b098676da0e967eb (MD5) / Made available in DSpace on 2018-08-17T14:30:53Z (GMT). No. of bitstreams: 1 EDICARLOS PEREIRS DE SOUSA - TESE (PPGMet) 2016.pdf: 7117312 bytes, checksum: 96b3ee401a9f1387b098676da0e967eb (MD5) Previous issue date: 2016-05-31 / Capes / O estado de Minas Gerais, localizado na região Sudeste do Brasil, possui um território planáltico, com áreas mais elevadas situadas na porção sul. O clima é predominantemente tropical e tropical de altitude, com temperaturas oscilando, normalmente, entre 17 e 20°C. Tais características o tornam, muitas vezes, susceptível a fortes chuvas, provocando transtornos diversos à população. Desse modo, buscou-se analisar a variabilidade da chuva mineira através de técnicas que fossem capazes de definir padrões espaciais e temporais de eventos secos e chuvosos, assim como modulá-los nas escalas tempo-frequência. Para isso, calculou-se o Índice de Precipitação Normalizada (IPN) mensal e trimestral no período 1977-2012. A fim de encontrar padrões espaço-temporais e regiões homogêneas (RH) do IPN mensal e trimestral, utilizaram-se as técnicas da Análise em Componentes Principais (ACP) e Agrupamentos (AA). A técnica da Transformada de Ondeletas (TO) foi aplicada para algumas localidades das diferentes RH em diversas escalas. A TO possibilitou encontrar oscilações importantes no sinal da precipitação, mostrando as componentes dominantes da variabilidade da chuva na área pesquisada. Nos espectros de fase e global de energia da TO, para a chuva mensal, predominou o ciclo anual em todas as localidades. Além da escala anual, observaram-se interações com escalas inferiores a doze meses, possivelmente decorrentes da sazonalidade da precipitação. A TO da precipitação e da Radiação de Onda Longa (ROL) diárias evidenciou frequências maiores que as da chuva mensal. A análise dos espectros de fase e de energia global, nas regiões centro-sul e oeste, apresentou maior energia no início das séries da precipitação e de ROL. Contribuições mais elevadas ocorreram nas escalas sinóticas e intrassazonais, principalmente nas localidades de Viçosa, Bom Despacho, Ituiutaba e Lavras. Esses padrões temporais estão associados com a Oscilação de Madden-Julian (OMJ), intensificando a atuação de sistemas moduladores do clima de Minas Gerais. Oscilações em escalas menores que dez dias foram detectadas nos anos de 2011 e 2012 e podem estar associadas aos sistemas de curto prazo que contribuíram para a chuva mineira. No caso de 2011, os eventos de chuva observados em meados de janeiro foram modulados pelos episódios da Zona de Convergência do Atlântico Sul (ZCAS) e reforçados pela atuação da OMJ. / The state of Minas Gerais, located in southeastern Brazil, has a plateaux area, with higher areas in the southern part. The climate is predominantly tropical and tropical altitude, with temperatures ranging normally between 17 and 20°C. These characteristics make it often susceptible to heavy rains, causing many disorders the population. Thus, it sought to analyze the variability of the rain of Minas Gerais through techniques that were able to define spatial and temporal patterns of dry and wet events, and modulate them in the time-frequency ranges. For this, we calculated the Standardized Precipitation Index (SPI) monthly and quarterly in the period 1977-2012. In order to find spatiotemporal patterns and homogeneous regions (HR) of the monthly and quarterly SPI, we used the techniques of Principal Components Analysis (PCA) and Cluster Analysis (CA). The technique of Wavelets Transform (WT) has been applied to some locations of the different HR at various scales. The WT possible find important variations in rainfall signal, showing the dominant components of rainfall variability in the studied area. In phase spectra and global energy of WT, for the monthly rainfall, dominated the annual cycle in all locations. In addition to the annual scale, there were interactions with scales less than twelve months, possibly due to the seasonality of precipitation. The WT of precipitation and Outgoing Longwave Radiation (OLR) daily reported higher frequencies than the monthly rainfall. Analysis of phase spectra and global power, in south-central and western regions, showed higher energy at the beginning of the series of precipitation and OLR. Higher contributions occurred in the synoptic and intraseasonal scales, especially in the localities of Viçosa, Bom Despacho, Ituiutaba and Lavras. These temporal patterns are associated with the Madden-Julian Oscillation (MJO), intensifying the activity of modulators systems climate of Minas Gerais. Oscillations at smaller scales than ten days were detected in 2011 and 2012 and may be associated with short-term systems that contributed to the Minas Gerais rainfall. In the case of 2011 rain events observed in mid-January they were modulated by episodes of South Atlantic Convergence Zone (SACZ) and reinforced by the performance of MJO.
235

Um método para correção automática de cartão de resposta utilizando processamento digital de imagem / A method for automatic correction of multiple-choice tests using digital image processing

Pereira, Pedro Henrique 27 April 2018 (has links)
Submitted by Pedro Henrique Pereira (pedro.pereirasp@gmail.com) on 2018-06-26T14:21:28Z No. of bitstreams: 1 DissertaçãoPedroHenriquePereira_VersãoFinal.pdf: 4177619 bytes, checksum: 063cd34385c56ed5081e839a845767b5 (MD5) / Approved for entry into archive by Cristina Alexandra de Godoy null (cristina@adm.feis.unesp.br) on 2018-06-26T17:55:12Z (GMT) No. of bitstreams: 1 pereira_ph_me_ilha.pdf: 4177619 bytes, checksum: 063cd34385c56ed5081e839a845767b5 (MD5) / Made available in DSpace on 2018-06-26T17:55:12Z (GMT). No. of bitstreams: 1 pereira_ph_me_ilha.pdf: 4177619 bytes, checksum: 063cd34385c56ed5081e839a845767b5 (MD5) Previous issue date: 2018-04-27 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Neste trabalho propõe-se um método que envolve diferentes técnicas de processamento digital de imagem para a correção automática de cartão de respostas utilizados em avaliações de múltipla- escolha, vestibulares, concursos ou processos de seleção. O método tem como base um modelo de referência onde são identificados os seguintes elementos do cartão: campos de marcação das opções, número de opção de cada questão e uma imagem de marcação para identificar as extremidades da folha. No trabalho foi aplicada a técnica de Correlação Cruzada Normalizada para identificação da imagem na extremidade da folha. A Transformada de Hough foi utilizada para identificação das áreas onde se realiza a marcação das opções. Para identificar qual a questão que foi marcada utilizou-se a contagem de pixel. Foram realizados testes com 1.154 gabaritos contendo 40 questões, preenchidos no vestibular de uma faculdade particular. O tempo médio para correção de cada cartão foi de 1,39 segundos. A precisão do método foi avaliada utilizando-se 5% dos cartões digitalizados e processados. Basicamente, a avaliação foi realizada conferindo-se visualmente cada cartão e comparando os resultados com os gerados pela correção automática. O índice de acerto com as amostras utilizadas foi de 100%, o que comprova a eficiência do método proposto. / This work proposes a method that involves different techniques of digital image processing for automatic correction of card responses used in multiple-choice evaluations, “vestibular”, contests or selection processes. The method is based on a reference model where the following elements of the card are identified: marking fields of the options, the option number of each question and a marking image to identify the edges of the sheet. In this work, the Normalized Cross-Correlation technique was applied to identify the image at the leaf end. The Hough Transform was used to identify the areas where the options are marked. To identify which question was selected, the pixel count was used. We performed tests with 1.154 templates containing 40 questions that were completed in the entrance examination of a private college. The average time to correct each card was 1.39 seconds. Samples were collected on 5% of the scanned and processed cards by the method to verify their accuracy. The total sampled was visually checked with the results presented by the application of the method and it was verified the percentage of 100% of correct answers in the reading of the markings. / CAPES: 515/2017
236

Péče o adolescenty před a po operaci fimózy s využitím klasifikačních systémů NANDA, NIC a NOC / Care of adolescents before and after operation of phimosis using classification systems NANDA, NIC and NOC

KOŽÍŠKOVÁ, Zlata January 2015 (has links)
This thesis focuses on the issue of nursing care for adolescent boys who have undergone phimosis surgery. The nursing care is then evaluated according to the NANDA, NIC and NOC classification systems. The theoretical part deals with topics such as adolescence, phimosisa disease of the external genitalia of a man, preoperative and postoperative care for boys with phimosis, and the classification taxonomy of the NANDA, NIC and NOC classification systems, which represent the comprehensive standardized, but still evolving, nursing language. Available Czech and foreign literary sources were used for the compilation of the theoretical part of the stated subject. The empirical part of the thesis was processed using qualitative and quantitative research methods: content analyzes, modelling, thought experiment, structured and semi-structured interviews, and qualitative data analysis. Four objectives were defined. The way adolescent boys perceive and experience the bio-psycho-social aspects of the problems that the pre-op and post-op period brings, has been assessed using the NANDA, NIC and NOC classification systems. There were 46.66% of respondents with higher education, 53.34% of respondents with secondary education, and eight adolescent boys who had received phimosis surgery, all of whom contributed to the assessment. It was found that adolescent boys initially addressed their physician regarding the phimosis problem, because they had a sense of trust and anonymity, but also to some degree because of necessity. It is surprising that young men with this type of personal problem rather speak to their mothers. When it comes to peer relationships, the boys confide the problem to their peers, but they do not ask them for help in this area. The boys named the internet as the main source of information. The following assessments were made using the Fehring methods for determining the weighted scores. Out of 13 nursing diagnoses within the NNN classification systems there were 112 major and minor characteristics (41.18%) selected by the university educated respondents, 80 major and minor characteristics (29,41%) selected by by the secondary school educated respondents, and nine major and minor characteristics (3.31%) were selected by the adolescent boys. Out of the 15 nursing interventions published in the Nursing Interventions Classification (NIC), 203 major and minor characteristics (55.31%) were chosen by the university educated respondents and 235 major and minor characteristics (64.03%) were chosen by the secondary school educated respondents. Out of the 11 expected nursing outcomes published in the Nursing Outcomes Classification (NOC), 39 major and minor characteristics (15.42%) were selected by the university educated respondents, while 34 major and minor characteristics (13.44%) were selected by the secondary school educated respondents. By implementing the NANDA, NIC and NOC classification systems in nursing care one can expect to find solutions that help the professionals in nursing care to apply the nursing process effectively, and that allow nursing care to focus more on the individual needs of patients and to be improved in all areas.
237

Processeffektivisering av kantpressar / Streamlining of a press brake operation

Loodin-Ek, Hanna, Schalin, Rebecka January 2018 (has links)
Studien undersöker processen i plåthallen vid kantpressarna på Systemair Sverige AB i kommunen Skinnskatteberg. Systemair Sverige AB är ett företag som tillverkar luftridåer, ventilationssystem och luftaggregat och är ledande på marknaden inom sitt område. Systemair Sverige AB anser att processen sker ineffektivt vid kantpress vilket ger oönskade och långa ställtider. Målbilden för studien var då att hitta relationer mellan artiklar som går igenom kantpressarnas flöde och därefter dela in verktygen för att få ner ställtiderna. Tillvägagångsättet är av analyserande karaktär och följer en PDCA (Plan, Do, Check, Act) struktur där ett antal frågor formulerades i början och som diskuteras i rapportens gång. Studien inleds med en grundlig nulägesanalys där verktyg inom Lean identifierades för att bemöta och hantera det uttalade problemet. Exempel på verktyg som användes är flödeskarta, produktionsflöde och produktfamiljer. Metoderna anpassades utefter studien och resulterade i en verktygsindelning. Utifrån verktygsindelningen har en procentuell indelning kunnat göras vilket ger upphov till nya flöden och som presenteras i rapporten. Projektgruppen har berört artiklar som behandlats av standardverktyg inom Prägling och Luftbock samt verktyg inom dessa områden utöver standard. För att få ner ställtiden så har en SMED-analys (Single-digit Minute Exchange of Die) utförts varav det har plockats ut en tidsstudie. Den längsta uppmätta ställtiden var på 43 minuter vilket projektgruppen tror går att reducera till 16 minuter genom verktygsindelningen. Då detta inte var i enlighet med SMED, där målet är att ställtiden ska vara under 10 minuter, så gavs indikationer på att fler faktorer spelade in varav en Ishikawa (rotorsaksanalys) upprättades. För att nå detta SMED-mål så gavs fortsatta rekommendationer varav ett är standardiserat arbetssätt. Slutligen presenterades tre förslag gällande effektiviseringen av kantpress, alla inom verktygsindelningen, och de frågeställningarna besvarades i slutsatsen. / The report studies the process by the press brakes at Systemair Sweden AB in the county of Skinnskatteberg. Systemair Sweden AB is a company that produce air curtains, residential ventilation, air conditioning devices and is leading within its own market of products. Systemair Sweden AB consider the press brake process to be inefficient which result in unwanted and long set up time. The intention of the report was to find the relations between products that are being processed in the press brake and thereafter sort each individual product stream by similarities in the equipment being used to reduce the set-up time. The approach of the report is of analyzing character and has a PDCA (Plan, Do, Check, Act) framework where a few questions are enunciated in the beginning of the report and discussed throughout the report. The report initiates in a thorough status analysis where tools within the theory of Lean is identified and used to handle the mentioned problem. Examples of tools being used is a production map, production flow and production families. The methods are adapted for this problem and report which resulted in a classification in equipment. A percental division was established by the classification which sourced new defined production flows and are presented in the report. The project group has focused on products produced with standard equipment in the two most used press types and a few products being processed by other equipment. To reduce the press brakes long set-up times a SMED analysis (Single-digit Minute Exchange of Die) has been implemented and a clock study. The longest set-up time in this study was in 43 minutes which the project group think can be reduced till 16 minutes by classifying equipment. According to SMED, a set-up time under 10 minutes is achievable, which is not the case here which indicated that there are more factors having to be in consideration. Therefore an Ishikawa (analysis of causes) was made in order to acknowledge these factors and recommendations was given to continue the work whereof one recommendation was standardized work methods. In the final of the report three suggestions are presented to streamline the press-brake process, all formed through classification of equipment, and lastly the questions from the beginning are answered.
238

The Cross-sectional and Longitudinal Relationships of Early Childhood School Assessment Policies with Reading Instruction and Reading Achievement: Evidence from Early Childhood Longitudinal Study

January 2015 (has links)
abstract: The purposes of this study were (1) to examine the direct and indirect effect of school-level testing policies on reading achievement though changes in amount and types of reading instruction, (2) to investigate the reading trajectories moderated by school-level testing policies longitudinally, and (3) to examine the relationship between testing policies and the achievement gap by exploring whether certain student characteristics moderate the relationship between testing policy and reading achievement, using Early Childhood Longitudinal Study Kindergarten (ECLS-K) Cohort of 2010-2011 data. Findings from a multilevel full structural mediation model suggest that school-level frequency of state/local standardized tests had an indirect effect on student reading achievement through changes in both amount and the types of instruction at the school-level (cross-sectional fall kindergarten sample =12,241 children nested in 1,067 kindergarten classes). The findings from a three-level growth models indicated only children of Asian background and children from high socio-economic backgrounds who had frequent standardized tests in kindergarten accelerated in their monthly reading growth, whereas other children (e.g., low SES, non-Asian children) did not show any changes in the rate of the reading growth (longitudinal sample from fall of kindergarten to spring of first grade = 7,392 children nested in 744 kindergartens). The findings from the current study suggest that testing policy is not an effective means to reduce the achievement gap of children from disadvantaged family backgrounds, underperforming children or that children from low socieo-economic backgrounds. These children did not seem to benefit from frequent standardized tests longitudinally. Implications for supporting school assessment practices and instruction are discussed. / Dissertation/Thesis / Doctoral Dissertation Curriculum and Instruction 2015
239

Um método para correção automática de cartão de resposta utilizando processamento digital de imagem /

Pereira, Pedro Henrique January 2018 (has links)
Orientador: Jozué Vieira Filho / Resumo: Neste trabalho propõe-se um método que envolve diferentes técnicas de processamento digital de imagem para a correção automática de cartão de respostas utilizados em avaliações de múltipla- escolha, vestibulares, concursos ou processos de seleção. O método tem como base um modelo de referência onde são identificados os seguintes elementos do cartão: campos de marcação das opções, número de opção de cada questão e uma imagem de marcação para identificar as extremidades da folha. No trabalho foi aplicada a técnica de Correlação Cruzada Normalizada para identificação da imagem na extremidade da folha. A Transformada de Hough foi utilizada para identificação das áreas onde se realiza a marcação das opções. Para identificar qual a questão que foi marcada utilizou-se a contagem de pixel. Foram realizados testes com 1.154 gabaritos contendo 40 questões, preenchidos no vestibular de uma faculdade particular. O tempo médio para correção de cada cartão foi de 1,39 segundos. A precisão do método foi avaliada utilizando-se 5% dos cartões digitalizados e processados. Basicamente, a avaliação foi realizada conferindo-se visualmente cada cartão e comparando os resultados com os gerados pela correção automática. O índice de acerto com as amostras utilizadas foi de 100%, o que comprova a eficiência do método proposto. / Abstract: This work proposes a method that involves different techniques of digital image processing for automatic correction of card responses used in multiple-choice evaluations, “vestibular”, contests or selection processes. The method is based on a reference model where the following elements of the card are identified: marking fields of the options, the option number of each question and a marking image to identify the edges of the sheet. In this work, the Normalized Cross-Correlation technique was applied to identify the image at the leaf end. The Hough Transform was used to identify the areas where the options are marked. To identify which question was selected, the pixel count was used. We performed tests with 1.154 templates containing 40 questions that were completed in the entrance examination of a private college. The average time to correct each card was 1.39 seconds. Samples were collected on 5% of the scanned and processed cards by the method to verify their accuracy. The total sampled was visually checked with the results presented by the application of the method and it was verified the percentage of 100% of correct answers in the reading of the markings. / Mestre
240

Revisão sistemática da interferência da normalização do fator de crescimento semelhante à insulina tipo 1 (IGF-1) e redução do hormônio de crescimento (GH) randômico na mortalidade dos pacientes com acromegalia / Systematic review of the interference of normalization of growth factor to insulin type 1 (IGF-1) and reduction of growth hormone (GH) in the mortality of patients with acromegaly

Bolfi, Fernanda [UNESP] 22 February 2017 (has links)
Submitted by FERNANDA BOLFI null (febolfi@gmail.com) on 2017-05-08T16:04:44Z No. of bitstreams: 1 Dissertacao Final Fernanda Bolfi - 05 maio 2017.pdf: 3208040 bytes, checksum: c59f4d1e79a78aa785e21f71d553f965 (MD5) / Approved for entry into archive by Luiz Galeffi (luizgaleffi@gmail.com) on 2017-05-08T17:11:23Z (GMT) No. of bitstreams: 1 bolfi_f_me_bot.pdf: 3208040 bytes, checksum: c59f4d1e79a78aa785e21f71d553f965 (MD5) / Made available in DSpace on 2017-05-08T17:11:23Z (GMT). No. of bitstreams: 1 bolfi_f_me_bot.pdf: 3208040 bytes, checksum: c59f4d1e79a78aa785e21f71d553f965 (MD5) Previous issue date: 2017-02-22 / Objetivo: esta revisão sistemática da literatura e metanálise comparou a taxa da mortalidade na acromegalia com a taxa esperada na população geral dos estudos publicados antes de 2009 versus estudos publicados após. Métodos: foram criadas três estratégias de busca gerais e adaptáveis às bases de dados eletrônicas na área da saúde: Embase (1980–2015), Pubmed (1966–2016) e Biblioteca Virtual da Saúde (1982–2016). Foram incluídos estudos observacionais em que a mortalidade na acromegalia foi comparada à da população geral, por meio do número de mortes observadas nessa doença em comparação à taxa de mortalidade esperada para população geral (O/E). A partir do O/E, recalculamos todos os Standardized Mortality Ratio (SMR) e os seus respectivos intervalos de confiança (IC) que foram plotados em uma metanálise. Resultados: foram identificadas 1005 referências, dois revisores independentemente leram os títulos e resumos desses artigos. Dos 27 estudos potencialmente elegíveis, 23 foram incluídos e quatro foram excluídos por não preencherem os critérios de elegibilidade. A mortalidade geral na acromegalia foi significativamente superior a da população geral (SMR: 1,66, IC 1,44 - 1,93, p < 0,00001, I2 84%). Separando os artigos publicados a partir de 2009, a mortalidade na acromegalia não foi significativamente diferente 1,29 (IC 0,95-1,76, p=0,10, I2 86%). Nas análises por subgrupo de acordo com o status da doença, sete estudos consideraram como curados os pacientes que apresentaram a normalização do IGF-1 associado ao GH randômico < 2,5 ng/mL. Nesses indivíduos o SMR da metanálise foi 0,93 (IC 0,74-1,18, p=0,57, I2 33%) e dos que não atingiram esses critérios foi 2,23 (IC 1,53-3,27, p<0,00001, I² 61%). A mortalidade manteve-se significativamente maior nas causas cardiovasculares, respiratórias e cerebrovasculares [SMR: 1,78 (IC 1,52-2,10, p<0,00001, I² 49%), SMR: 2,29 (IC 1,63-3,23, p<0,00001, I² 49%), SMR: 2,62 (1,72-3,98, p<0,00001, I² 83%), respectivamente]. A metanálise dos que realizaram radioterapia evidenciou SMR de 2,15 (1,83-2,53, p<0,00001, I² 0%) e dos que não realizaram de 1,27 (0,95-1,69 p=0,11, I² 65%). Conclusão: apesar da alta inconsistência, não há diferença na mortalidade na acromegalia atualmente em comparação com períodos anteriores (antes e após 2009), e o controle bioquímico da doença com IGF-1 normal e GH randômico < 2,5 ng/mL está relacionado com normalização das taxas de mortalidade. / Objective: This systematic literature review and meta-analysis compared the mortality rate in acromegaly with the expected rate in the general population of studies published before 2009 versus studies published after. Methods: three general and adaptive search strategies were created from the electronic databases in the health area: Embase (1980-2015), Pubmed (1966-2016) and Virtual Health Library. Observational studies were included in which the mortality in acromegaly was compared to the general population, the number of deaths observed compared to the expected mortality rate in the general population (O/E). From O/E, we recalculated all the Standardized Mortality Ratio (SMR) and their respective confidence intervals (CI) that were plotted in a meta-analysis. Results: 1005 references were identified and two reviewers independently read the titles and abstracts of these articles. Of the 27 potentially eligible studies, 23 were included and four were excluded because they did not meet the eligibility criteria. Overall mortality in acromegaly was significantly higher than the general population (SMR: 1.66, CI 1.44 - 1.93, p <0.00001, I² 84%). Analyzing articles published as of 2009, the mortality in acromegaly was not significantly different, SMR 1.29 (CI 0.95-1.76, p = 0.10, I² 86%). In subgroup analyzes according to disease status, seven studies considered patients with IGF-1 normalization associated with random GH <2.5 ng / mL as cured. In these individuals, the SMR was 0.93 (CI 0.74-1.18, p = 0.57, I² 33%) and in those who did not meet these criteria were 2.23 (CI 1.53-3.27, p<0.00001, I² 61%). Mortality was significantly higher in cardiovascular, respiratory and cerebrovascular causes [SMR: 1.78 (CI 1.52-2.10, p <0.00001, I² 49%), SMR: 2.29 (CI 1.63-3.23, p <0.00001, I² 49%), SMR: 2.62 (1.72-3.98, p <0.00001, I² 83%), respectively]. The meta-analysis of those who underwent radiotherapy showed SMR 2.15 (1.83-2.53, p <0.00001, I² 0%) and those who did not performed, 1.27 (0.95-1.69 p = 0.11, I² 65%). Conclusion: Although there is a lot of inconsistency, there is no difference in acromegaly mortality compared to previous periods (before and after 2009), and the biochemical control of the disease with normal IGF-1 and random GH <2.5 ng / ml is related to normalization in mortality rates.

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