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Ports are actively pursuing greater operational efficiency to effectively handle the increasing global flow of goods, while striving to improve the energy efficiency of their operations to comply with new environmental regulations. As a result, innovation-leading ports have begun to recognize the potential of digital twins to overview, coordinate and optimize port processes, resulting in energy savings, and reductions of costs and of CO2 emissions. While digital twins have gained momentum in other domains such as smart manufacturing and aerospace, their adoption in ports has been comparatively slow. This can be explained, among other things, by the multi-stakeholder nature of the port and the high complexity of the often interconnected port processes. Thus, this thesis, grounded in the context of ports, discusses what constitutes a digital twin, proposes characteristics to assess the maturity of existing digital twins, and introduces and evaluates mathematical models to support a key port process, which can be used as components of a digital twin for the port. / Hamnar strävar aktivt efter ökad operativ effektivitet för att hantera den ökande globala varuflödet, samtidigt som de strävar efter att förbättra energieffektiviteten. Som ett resultat har ledande hamnar börjat se potentialen hos digitala tvillingar för att skapa överblick samt koordinera och optimera processer i hamnen. Målet med användningen av digitala tvillingar är energibesparingar samt minskning av kostnader och CO2-utsläpp. Medan digitala tvillingar har använts inom andra områden såsom tillverknings-, flyg- och rymdindustrin, har införandet i hamnar varit jämförelsevist långsamt. Detta kan förklaras, bland annat, av hamnens många olika involverade aktörer och den höga komplexiteten i de ofta sammanlänkade hamnprocesserna. Därför fokuserar denna avhandling, med utgångspunkt i hamnkontexten, vad som utgör en digital tvilling, presenterar egenskaper för olika mognadsnivåer hos befintliga digitala tvillingar, och introducerar samt utvärderar matematiska modeller som kan bli delkomponenter i en digital tvilling för hamnen.

<p dir="ltr">Recent advancements in Machine Learning (ML) algorithms and increasing computational power have driven significant progress in Artificial Intelligence (AI) systems, especially those that leverage ML techniques. These AI-enabled systems incorporate components and data designed to simulate learning and problem-solving, distinguishing them from traditional systems. Despite their widespread application across various industries, certifying AI systems through verification and validation remains a formidable challenge. This difficulty primarily arises from the probabilistic nature of AI and ML components, which leads to unpredictable behaviors.</p><p dir="ltr">This dissertation investigates the verification and validation aspects within the Systems Engineering (SE) lifecycle, utilizing established frameworks and methodologies that support system realization from inception to retirement. It is comprised of three studies focused on applying formal methods, particularly model checking, to enhance the accuracy, value, and trustworthiness of models of engineered systems that use digital twins for modeling the system. The research analyzes digital twin data to understand physical asset behavior more thoroughly by applying both an exploratory method, system identification, and a confirmatory technique, machine learning. This dual approach not only aids in uncovering unknown system dynamics but also enhances the validation process, contributing to a more robust modeling framework.</p><p dir="ltr">The findings provide significant insights into the model-based design of AI-enabled digital twins, equipping systems engineers<del>,</del> and researchers with methods for effectively designing, simulating and modeling complex systems. Ultimately, this work aims to bridge the certification gap in AI-enabled technologies, thereby increasing public trust and facilitating the broader adoption of these innovative systems.</p>

本研究旨在探討人口變項、父母教養行為、依附關係與雙胞胎的個人化之關係。本研究以76位成年雙胞胎為研究參與者（男性31人，女性45人），所使用的工具包括「雙胞胎個人化量表」、「雙胞胎父母教養行為量表」及「雙胞胎依附關係量表」。資料分析以描述統計、單因子單變量變異數分析、單因子多變量變異數分析及多元迴歸等統計方法進行分析。 本研究的主要發現如下： 一、 在現況方面，本研究之成年雙胞胎在個人化及依附關係的的得分偏高。在父親及母親教養行為的類別以父母親使用較多「情感支持」行為的成年雙胞胎居多；依附關係的類別則以屬於「安全天堂」及「趨近尋求」等安全依附關係的成年雙胞胎人數最多。 二、 不同人口變項的成年雙胞胎，其個人化程度有差異。不同年齡、雙胞胎本身的社經地位在個人化的有顯著差異。而不同性別、父母的社經地位、胎性、雙胞胎排行、家中手足總數的成年雙胞胎在個人化則沒有顯著差異。 三、 經歷不同父親及母親教養行為的成年雙胞胎，其個人化的程度有差異，即父親及母親「情感支持」教養行為較多，整體「個人化」及「分化」的程度較高；父親「拒絕」教養行為使用較多，則「獨立」的程度較低。 四、 不同依附關係的成年雙胞胎，其個人化的程度沒有差異。 五、 父親「情感支持」教養行為、母親「情感支持」教養行為、「趨近尋求」依附關係、「安全天堂」依附關係，對個人化的表現有正向預測效果。其中以父親「情感支持」行為的預測效果最好。 六、 父親「拒絕」教養行為、父親「一致性」教養行為、母親「拒絕」教養行為、母親「一致性」教養行為、「分離抗拒」依附關係對個人化的表現有負向預測效果。其中以父親「拒絕」教養行為為主要預測變項，其次是母親「拒絕」教養行為。 最後，根據本研究之主要發現提出若干建議，以供雙胞胎父母與未來研究之參考。 關鍵詞：成年雙胞胎、個人化、父母教養行為、依附關係 / The main purpose of this study was to explore the relationships between adult twins’ parental rearing behaviors, attachment relationship, demographic variables and their individuality. The participants were 76 adult twins (31 males and 45 females). The employed instruments included Individuality Inventory for Twins, Parental Rearing Behavior Inventory for Twins, and Attachment Relationship Inventory for Twins. The applied analysis methods were Descriptive Statistics, One-way Multivariate Analysis of Variance, One-way Analysis of Variance, and Multiple Regression. The main findings of this study were as follows: 1. The adult twins in this study had an above-average level of individuality and attachment relationship. As for the categories, most twins belonged to the attachment of “safe heaven” and “proximity seeking,” and most twins belonged to the parental rearing behavior of “emotional warmth”. 2. The adult twins’ age and socioeconomic status had significant effects on their performance of individuality. However, the adults twins’ gender, zygosity, birth order of twins, number of siblings, and their parents’ socioeconomic status had no significant effects on their performance of individuality. 3. The adult twins who experienced different parental rearing behaviors had varied level of individuality. More specifically, those who experienced more parental behaviors of “emotional warmth” outperformed their counterparts in overall individuality and the index of “differentiation,” while those who experienced less “rejection” behaviors from their fathers outperformed their counterparts in the index of “independence”. 4. Adult twins with different attachment relationship did not differ in their performance of individuality. 5. Father’s and mother’s rearing behaviors of “emotional warmth” and the attachment of “proximity seeking” and “safe heaven,” especially father’s rearing behaviors of “emotional warmth,” could positively predict the adult twins’ performance of individuality. 6. Father’s and mother’s rearing behaviors of “rejection” and “consistency” and the attachment of “separation protest,” especially father’s rearing behaviors of “rejection,” could negatively predict the adult twins’ performance of individuality. Finally, after discussion, some suggestions were proposed for the parents of twins and future research. Keywords: Adult Twins, Individuality, Parental Rearing Behaviors, Attachment Relationship.

雖然政治學界廣泛地討論水資源安全的問題, 可是迄今為止絕大部分的研究採取合作衝突相兩者互排斥的分析方法。有些學派主張水資源短缺一定導致衝突, 而制度主義學派認為在大多數情況下水資源安全推動國際合作。環境安全與衝突研究中的科學共識認為水資源不是衝突的起因而是合作的理由, 於是繼續提倡合作衝突兩者相互排斥的概念。筆者認為如今的非黑即白分析尚未能夠正確描述水資源安全的衝突合作相互作用的實際。碰到了這個研究空白的問題, 筆者應用 Naho Mirumachi發展的「TWINS」架構來檢視印度-巴基斯但與印度-孟加拉關係中的水資源安全。「TWINS」架構讓我們深入地檢視「1996年12月12日印孟簽署分享恆河水條約」與「1960印度河水域條約」這兩個條約。新世紀增長需求跟耗盡水資源的問題越來越清楚地標明, 根據這兩個條約，水資源的供水與解決衝突能力有限。雖然被視為跨界河川合作的成功故事, 可是這兩個條約不足消除潛在衝突, 而進一步表明衝與合作是同時存在的。最近印度政府表明關於水資源的政策改變, 比如最佳地利用1960印度河水域條約的規定或清拆法拉卡堰。為了防止安全化過程升高, 立即開展有意義的對話至關重要。 關鍵字: 印度-巴基斯但、印度-孟加拉、水資源安全、TWINS

L’amusie congénitale est un trouble neuro-développemental se définissant par des difficultés à percevoir la musique, et ce malgré une ouïe et une intelligence normales. Un déficit de discrimination fine des hauteurs serait à l’origine de ce trouble, qui se traduit notamment par une incapacité à détecter les fausses notes. afin de mieux comprendre les facteurs génétiques contribuant à la manifestation de l’amusie congénitale, la présente étude avait pour objectif: (a) de déterminer si la performance sur diverses tâches musicales et auditives était plus similaire chez les jumeaux identiques (monozygotes ; MZ) que chez les jumeaux non-identiques (dizygotes ; DZ) et (b) d’explorer les variables relatives à l’environnement musical des jumeaux, afin de mieux comprendre les contributions de l’environnement et de la génétique dans les différences sous-tendant les habiletés musicales. De plus, le profil des sujets amusiques a été analysé afin de vérifier s’il correspondait à celui décrit dans la littérature, faisant état de difficultés tonales, mais non rythmiques. Huit paires de jumeaux MZ et six paires de jumeaux DZ, parmi lesquelles au moins un des co-jumeaux était potentiellement amusique, ont pris part à cette étude. Les tâches consistaient en un test en ligne de perception mélodique et rythmique, un test de détection des différences de hauteurs, ainsi qu’un test de chant. L’analyse de la performance et de l’environnement musical des jumeaux MZ et DZ ne révèle aucune distinction comportementale entre ces deux groupes en ce qui concerne les habiletés musicales. Cela suggère que celles-ci puissent être davantage influencées par l’environnement partagé que par les facteurs génétiques. Enfin, les jumeaux amusiques ont le profil habituel d’habiletés musicales. En effet, ils commettent des erreurs de perception et de production musicale au niveau mélodique, mais ont une perception rythmique préservée. D’autres études, notamment avec de plus grands échantillons de jumeaux, seront nécessaires afin d’élucider la possible étiologie génétique sous-tendant l’amusie congénitale. / Music is an important part of every known culture, and its universality raises the question of a possible biological basis. Musical disorders, such as congenital amusia, offer compelling insight into these roots. In order to examine the genetic basis of this phenotype, we used a classical twin study paradigm. Our study had two main goals: (a) investigate if identical (monozygotic; MZ) co-twins perform more similarly on auditory and musical tasks than non-identical (dizygotic; DZ) co-twins and (b) explore the twins’ musical environments in order to better understand the contribution of environmental versus genetic factors in the differences underlying musical abilities. In addition, we sought to replicate previous investigations that demonstrated impaired pitch processing but intact rhythm perception in amusic participants. To do so, we tested eight pairs of MZ and six pairs of DZ twins in which at least one of the co-twins was potentially amusic. Participants completed an online amusia test, a pitch detection task and a singing task. We observed no performance or musical environment differences between MZ and DZ twins, suggesting that musical abilities might be more influenced by the twins’ shared environment than by genetic factors. In addition, and as reported in previous studies, amusics made pitch processing errors in both perception and production, but rhythmic perception was preserved. Future studies, particularly those with access to larger twin samples, will be able to further elucidate the roles of environmental and genetic factors in the amusic phenotype.

Preeclampsia (PE), characterized by hypertension and proteinuria after 20 weeks of gestation, affects 5-8% of pregnancies worldwide. Although preeclampsia is a significant cause of maternal and perinatal mortality and morbidity, its etiology remains to be elucidated. Racial differences have been observed for preeclampsia, with U.S. Blacks having higher rates and more severe disease, compared to U.S. Whites and Hispanics. One potential source of racial differences in preeclampsia is genetic variation between populations. Genetic susceptibility to preeclampsia is well established, but the specific contributions of maternal vs. fetal genes, and how these vary among racial groups is poorly understood. This dissertation addressed racial differences in the genetics of preeclampsia in Chileans, U.S. Blacks, and U.S. Whites through candidate gene studies and variance components modeling. First, we determined whether three genes, which are relevant to the pathophysiology of preeclampsia, Catechol-O-methyltransferase (COMT), Methylenetetrahydrofolate reductase (MTHFR), and Endoplasmic reticulum aminopeptidase 2 (ERAP2), were associated with the risk for preeclampsia in Chilean and U.S. Black mothers and fetuses. We found that the maternal COMT and an interaction between the fetal COMT and MTHFR were associated with the risk for preeclampsia in Chileans. We also found that the fetal ERAP2 was associated with the risk for preeclampsia in U.S. Blacks. We next used structural equation modeling of a unique Children of Twins (COT), supplemented with full and half-siblings, study design to investigate the fetal genetic, maternal genetic, shared environmental, and unique environmental contributions to preeclampsia in U.S. Whites and Blacks. Through this modeling we uncovered a unique source of racial differences in preeclampsia. We found that U.S. Whites and Blacks showed a similar prevalence of preeclampsia in first births, but across the next three births, the prevalence in Whites declined to a greater degree than in Blacks. In conclusion we have identified specific maternal and fetal genes that contribute to the risk for preeclampsia. Furthermore, we have identified sources of racial differences in preeclampsia, which include differences in associations between COMT, MTHFR, and ERAP2 and the risk for preeclampsia among populations and differences in the prevalence of preeclampsia across subsequent births between U.S. Whites and U.S. Blacks.

Contexte et objectifs. Le contrôle de soi serait, selon Gottfredson et Hirschi (1990), le meilleur prédicteur de la délinquance. Il serait déterminé, selon les auteurs, exclusivement par les facteurs environnementaux (compétences parentales, surveillance et punition) et ce, avant l'âge de sept ans. Il ne serait pas question des facteurs génétiques dans l'étiologie du contrôle de soi. Or, plusieurs études récentes menées à l'adolescence et à l'âge adulte avancent que le contrôle de soi serait d'origine partiellement génétique. Deux objectifs seront poursuivis. D'abord, considérant que le contrôle de soi, tel que décrit par Gottfredson et Hirschi (1990), n'ait jamais été étudié spécifiquement à la petite enfance, il a été nécessaire d'opérationnaliser le construit à la petite enfance à partir des informations existantes sur le contrôle de soi. Ensuite, il s'agira d'estimer l’influence relative des facteurs génétiques et environnementaux sur le contrôle de soi à 18, 30 et 48 mois. Méthodologie. En tout, 672 familles de jumeaux monozygotes ou dizygotes de la grande région métropolitaine de Montréal ont pris part à l'Étude des jumeaux nouveau-nés du Québec. Les items utilisés proviennent du Child Behavior Checklist (Achenbach, 1994) et ont été obtenus via les parents des jumeaux. La zygotie a été évaluée à l’aide du Zygosity Questionnaire for Young Twins (Goldsmith, 1991) et le sexe a été déterminé par les assistants de recherché. Trois temps de mesures furent étudiés : 18 mois (n = 664), 30 mois (n = 617) et 48 mois (n = 531). Résultats. Les résultats des analyses factorielles confirmatoires suggèrent par le biais des estimés qu'il soit possible de générer un facteur du contrôle de soi à la petite enfance à partir des indicateurs sélectionnés et que ceux-ci se regroupent sous l'égide d'un seul facteur. Les résultats concernant l’étiologie montrent que les différences individuelles observées seraient, majoritairement influencées par les facteurs génétiques (additifs ou de dominance) suivis par les environnements uniques. Conclusion. Les résultats suggèrent que les facteurs génétiques jouent un rôle important dans l’étiologie des différences individuelles dans le contrôle de soi tôt dans le développement alors que les environnements communs ne seraient pas impliqués. Les résultats sont compatibles avec les études menées à l'adolescence et à l'âge adulte et sont en contradiction avec les postulats de Gottfredson et Hirschi (1990). / Context and goals. Self-control is described by Gottfredson and Hirschi (1990) as the most reliable predictor of delinquency. The authors suggest that self-control is determined primarily by environmental factors, including parental monitoring of their children, the recognition of bad behaviors, the appropriate correction of the bad behaviors, of which the individual differences are deemed stable by age seven. The main goal of this study was to examine the genetic and environmental etiology of self-control in toddlerhood. Specifically, this study aims to 1) evaluate whether self-control can be reliably operationalized in toddlerhood; and 2) estimate the genetic and environmental contributions of individual differences in self-control in this period of development. Methods. The sample consisted of 672 pairs of monozygotic or dizygotic twins who grew up in the greater Montreal area. Information about the twins were collected from the parent that knows the child best using the Child Behavior Checklist (Achenbach, 1994) whereas the zygosity was determined by the Zygosity Questionnaire for Young Twins (Goldsmith, 1991). For the purpose of this study, only three waves of data collection were used: 18 months (n = 332 pairs), 30 months (n = 309 pairs) et 48 months (n = 266 pairs). Results. The results support the idea self-control can be estimated from six behavioral and attitudinal indicators (impulsivity, disobedience, bad temper, aggressive behavior, hyperactivity and inattention) and derived in a single factor as early as 18 months of age. At 18, 30 and 48 months of age, the best fitted models indicated that only genetic and uniquely experienced environmental factors underlined individual differences in self-control. Interpretation. Contrary to Gottfredson and Hirschi’s (1990) hypothesis, individual differences in self-control in toddlerhood is moderately explained by genetic factors, the reminder being relegated to uniquely experienced environments. Also noteworthy is the absence of a shared-environmental etiology, part of which is expected to comprise family influences experienced by both twins, such as the parental monitoring of their children, the recognition of bad behaviors and the appropriate correction of the bad behaviors.

Objetivo: Comparar o desempenho de diferentes curvas de referência de crescimento fetal em gestações gemelares com insuficiência placentária grave. Método: Estudo retrospectivo envolvendo gestações gemelares (n=47), com fluxo diastólico zero ou reverso, no estudo dopplervelocimétrico da artéria umbilical de um dos fetos, e ambos os fetos vivos no momento do diagnóstico. Não foram incluídas gestações com anomalia fetal \"major\", síndrome de transfusão feto-fetal, ou de ordem maior. Em ambos os fetos (acometido, FA; e cogemelar, CG), as estimativas de peso fetal foram convertidas em escore zeta de acordo com os critérios de Hadlock, Liao e Araújo. As medidas de circunferência abdominal foram convertidas de acordo com as curvas de Hadlock, Liao, Araújo, Ong e STORK. A análise estatística foi realizada segundo modelos de equações de estimação generalizada. Resultados: A idade materna média foi 27,8 ± 7,4 anos, 24 (51%) pacientes eram primigestas, 12 (25,5%) apresentavam antecedentes clínicos significativos e 61,7% (n=29) eram monocoriônicas. A idade gestacional média no momento do diagnóstico da diástole zero ou reversa foi de 27,4 ± 4,7 semanas. A idade gestacional média do parto foi de 32,9 ± 2,9 semanas e o peso médio ao nascimento dos fetos acometidos foi de 1075 ± 469 g, e dos cogemelares, 1749 ± 544 g. No modelo investigado, foram preditores significativos do escore-zeta: sexo fetal (p < 0,001) e a interação sub-grupo (feto acometido/cogemelar) e critério (p < 0,001). As estimativas do escore zeta médio (erro padrão) para o peso fetal estimado segundo cada critério examinado foram Hadlock FA: -2.98 (0,18), CG: -1,16 (0,15), Liao FA: -2,89 (0,24), CG: -0,58 (0,19), Araújo FA: -3,05 (0,29), CG: - 0,75 (0,18). Para circunferência abdominal, Hadlock FA: -3,14 (0,26), CG: - 1,13 (0,19), Liao FA: -2,63 (0,27), CG: -0,42 (0,19), Araújo FA: -2,44 (0,22), CG: -0,71 (0,14), Ong FA: -3,36 (0,34), CG: -1,48 (0,23) e STORK FA: -2,36 (0,14), CG: -1,18 (0,10). Conclusão: Em gestações gemelares, com diástole zero ou reversa em um dos fetos, as curvas que melhor diferenciaram os fetos acometidos de seus cogemelares foram as curvas nacionais, publicadas por Liao et al. e Araújo et al / Objectives: To compare the performance of different fetal growth reference curves in twin pregnancies with severe placental insufficiency. Methods: Retrospective analysis of 47 twin pregnancies with absent or reverse end diastolic flow in the umbilical artery in one fetus, and both twins alive at diagnosis. Pregnancies with major fetal abnormality, twin-twin transfusion and higher order were not included. At each ultrasound evaluation, estimated fetal weight zeta-scores were calculated for both fetuses (abnormal Doppler, AD; co-twin, CT) according to the following criteria: Hadlock, Liao and Araújo. Abdominal circumference zeta-scores were calculated according to Hadlock, Liao, Araújo, Ong and STORK. Statistical analysis was performed with generalized estimating equation regression. Results: Mean maternal age was 27.8 ± 7.4 years, 24 (51%) women were primigravida, 12 (25.5%) had a previous clinical history and 29 (61.7%) were monochorionic. Gestational age at abnormal Doppler diagnosis was 27.4 ± 4.7 weeks. Gestational age at delivery was 32.9 ± 2.9 weeks and mean birthweight was 1075 ± 469 g for AD twin, and 1749 ± 544 g in CT group. Zeta-score values were significantly related to fetal sex (p < 0.001) and subgroup (abnormal Doppler/co-twin) versus criteria interaction (p < 0.001). Estimated fetal weight mean zeta-score (standard error) according to each criteria were: Hadlock AD: -2.98 (0.18), CT: -1.16 (0.15), Liao AD: -2.89 (0.24), CT: -0.58 (0.19), Araújo AD: -3.05 (0.29), CT: -0.75 (0.18). Values for abdominal circumference were: Hadlock AD: -3.14 (0.26), CT: -1.13 (0.19), Liao AD: -2.63 (0.27), CT: -0.42 (0.19), Araújo AD: -2.44 (0.22), CT: -0.71 (0.14), Ong AD: -3.36 (0.34), CT: -1.48 (0.23) and STORK AD: -2.36 (0.14), CT: -1.18 (0.10). Conclusion: In twin pregnancies with absent or reversed end diastolic flow in the umbilical artery of one fetus, affected fetuses and their co-twins are best differentiated by Liao et al. and Araújo et al. reference ranges

Este estudo tem como objetivo investigar o desenvolvimento psíquico de gêmeos abrigados no decorrer do primeiro ano de vida. Foram separados ao nascer, tendo como histórico inicial de vida, para um, a ausência do contato materno logo após o nascimento, tendo permanecido hospitalizado até os oito meses de vida e seguido para o abrigamento; e para o outro, a descontinuidade do contato materno e familiar aos dez meses de vida, seguido pelo abrigamento. No desenvolvimento deste estudo, os gêmeos estavam com cinco anos de idade, ainda abrigados, na mesma instituição e próximos da adoção. Trata-se de uma pesquisa qualitativa, do tipo estudo de caso, embasada pelo método psicanalítico, à luz dos pensamentos de D. W. Winnicott. Por meio do diagnóstico psicológico do tipo compreensivo e interventivo, com o emprego das técnicas projetivas hora de jogo e procedimento de desenhos-estórias, buscou-se a compreensão da vida intrapsíquica dos gêmeos. Instrumentos auxiliares como o estudo documental do histórico familiar, como também entrevistas realizadas no abrigo, colaboraram para o alcance de uma visão totalizadora dos casos. A partir da análise dos dados, observaram-se marcantes divergências do funcionamento psíquico dos gêmeos: aquele institucionalizado desde o nascimento apresenta maior interação ambiental e facilita o emprego de intervenções, diante de angústias depressivas emergentes, mostra comportamentos regressivos; o outro separado do lar aos dez meses, diante de angústias despertadas, utiliza-se de mecanismos defensivos de negação e evitação, cujas intervenções, por muitas vezes, são evitadas de modo a afastar a quebra do sistema defensivo operante. Quanto ao sistema defensivo, o primeiro apresenta comportamentos regressivos e fragilidade frente ao ambiente, além de dissociações entre movimentos regressivos e evoluídos; o segundo, mostra comportamentos agressivos e oposicionistas frente a limites e regras, como recursos para domínio e controle ambiental e agressões e violência nas relações, desencadeando dificuldades de interação com o ambiente, permanecendo isolado. Além dos aspectos clínicos observados, é possível conjeturar sobre a influência de aspectos psicopatológicos institucionais, especialmente quanto à clivagem dos gêmeos. Esta pesquisa também permitiu vislumbrar que prejuízos ao desenvolvimento também se desencadeiam de lares vitimizadores e não só de contextos institucionais; e que o processo de adoção deve ser mais bem estruturado, a fim de minimizar estados ansiógenos decorrentes, que observamos nos gêmeos, bem como a devolução da criança ao abrigo após sua adoção, como ocorreu com o segundo gêmeo. Dessa forma, concluiu-se que as crianças, mesmo em situação de abrigamento, apresentam aspectos saudáveis propulsores para a saúde e podem aproveitar experiências boas do ambiente, além de apresentarem capacidade para amar e estabelecer relações afetivas; por isso o contexto institucional merece assistência, principalmente psicológica, a fim de favorecer o ambiente e o desenvolvimento das crianças abrigadas. / This essay is aimed at investigating the psychic development of twins institutionalized since before one year of age. Parted at birth, one child is sent to a hospital where it stays for eight months before is sent to an institution. The child undergoes the absence of the early motherly contact. As for the other child, there is the early motherly contact and from the family, however, discontinued. At ten months of age, the child is then sent to the institution. The study is set up when the twins are five years old, and are still inmates at the same institution, and are on the verge of being adopted. This research is qualitative - a case study – grounded on the psychoanalytic method - according to D.W. Winnicott’s lights. By using comprehensive and intervening psychological diagnosis, as well as projective techniques such as Hour Game and the Drawing-stories procedure, it aims at understanding the intra-psychic life of the twins. Additional tools such as the documented study of the family history, along with the interviews carried out at the shelter, contribute to a thorough view of the cases. As data analysis is performed, expressive differences in the functioning psychic of the twins come to light: on the one hand, the child sent to the institution only just after birth shows more interaction with the environment, when confronted with emerging depressive anguish shows regressive behaviour. Also, the child makes it easy for the implementation of interventions. On the other hand, the child parted from its home at ten months of age reacts otherwise. This, when confronted by desperate anguish, utilises defence mechanisms such as negation and avoidance, whose interventions are, in most cases, avoided in order to maintain the ongoing defensive system. When it comes down to the defence system, of the two twins, the first shows regressive behaviour and fragility –as it faces the environment and dissociation in regressive and evolved movements. The second twin shows aggressive behaviour and opposition to limits and regulations as means of controlling the environment followed by aggression and violence in the relationships leading into difficulty in interacting and isolation from the environment. In addition to the clinical aspects, the influence of the psychopathological institutional aspects might also be pondered, such as the split-off the twins. The research, too, permits visualising what damages to the development come from oppressive homes and not only from institutional contexts, and that the adopting process should be thought over, and restructured in order to soothe the state of anxiety, as is observed in the twins during adoption, or the sending back to shelter of the second child, after its adoption. Thus, we conclude that even children under shelter can show healthy aspects, in that the children will benefit from the good experiences of the environment, and be able to love and hold affective relations. For this reason, the institutional context should be given assistance, principally psychological assistance, and then offers the children under shelter an appropriate environment which favours their development.