Submitted by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-03-28T16:52:20Z No. of bitstreams: 1 DIS_MARIA_CORTINA_BELLAN_COMPLETO.pdf: 860689 bytes, checksum: 3064d16c5e82cf67605dedf74fd70f61 (MD5) / Made available in DSpace on 2017-03-28T16:52:20Z (GMT). No. of bitstreams: 1 DIS_MARIA_CORTINA_BELLAN_COMPLETO.pdf: 860689 bytes, checksum: 3064d16c5e82cf67605dedf74fd70f61 (MD5) Previous issue date: 2016-11-29 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The aim of this study was to evaluate the bond strength (?TBS) of novel CAD/CAM restorative materials to different luting cements. Thirty two crowns were milled using CAD/CAM materials (Vita Mark II, Vita Suprinity, Vita Enamic and Lava Ultimate) and luted to sound and fresh cutted dentin using different cements (Relyx ARC, Relyx Unicem 2 and Relyx Ultimate). The specimens were stored in relative humidity of 100% at 37?C for 24 h and, then sectioned into sticks with water-cooled diamond blade with low-speed cutting saw. The samples (n=16) with cross-sectional areas of approximately 1 mm? were submitted to tensile bond strength test in a universal testing machine with crosshead speed of 0.5 mm/min. The samples were analyzed with SEM to determinate the failure mode. Data were analyzed using 2-way ANOVA and Tukey?s test (?=0,05). Bond strength was significantly affected by the material and interaction between them and luting cements (p=0.001). The ?TBS (MPa) values ranged from 12.17 for Vita Mark II with Relyx ARC and 32.93 for Lava Ultimate with Relyx Unicem 2. Considering overall behavior of tested materials Vita Enamic (29.39 MPa) and Lava Ultimate (28.42 MPa) obtained higher ?TBS values in comparison to Vita Mark II (14.14 MPa) and Vita Suprinity (14.55 MPa). The ?TBS values for Vita Enamic did not differ from those obtained with Lava Ultimate (p=0.845) and the same occurred with Vita Mark II and Vita Suprinity (p=0.986). There was no statistical difference between cements (p=0.176). A promising bonding performance can be achieved with the hybrid CAD/CAM restorative materials to tooth structure and to different types of luting cements after 24h of water storage. / O objetivo deste estudo foi avaliar a resist?ncia de uni?o (?TBS) dos novos materiais CAD/CAM a diferentes cimentos resinosos. Trinta e duas coroas foram usinadas utilizando materiais CAD/CAM (Vita Mark II, Vita Suprinity, Vita Enamic and Lava Ultimate) e cimentadas ? dentina h?gida, utilizando diferentes cimentos (Relyx ARC, Relyx Unicem 2 and Relyx Ultimate). As esp?cimes foram mantidas em umidade relativa de 100% a 37?C por 24 horas e ap?s seccionadas em palitos com disco diamantado em ?gua corrente. As amostras (n=16) com ?rea de aproximadamente 1 mm? foram submetidas ao teste de microtra??o atrav?s de uma m?quina universal com velocidade de carregamento de 0.5 mm/min. As amostras foram analisadas por MEV para determinar o modo de falha. Os dados foram analisados por meio do ANOVA de dois fatores e do teste Tukey (?=0,05). A resist?ncia de uni?o foi significantemente afetada pelo material e pela intera??o deste com os cimentos resinosos (p=0.001). Os valores de ?TBS variaram de 12.17 para Mark II com Relyx ARC e 32.93 para Lava Ultimate com Relyx Unicem 2. Considerando o comportamento geral dos materiais testados, Vita Enamic (29.39 Mpa) e Lava Ultimate (28.42 Mpa) obtiveram os maiores valores de ?TBS em compara??o ao Vita Mark II (13.13 MPa) e o Vita Suprinity (14.55 MPa). Os valores de ?TBS para Vita Enamic n?o diferiram estatisticamente daqueles obtidos com Lava Ultimate (p=0.845) e o mesmo ocorreu com Vita Mark II e Vita Suprinity (p=0.986). N?o houve diferen?a estat?stica entre os cimentos resinosos (p=0.176). Uma uni?o promissora pode ser alcan?ada com os materiais CAD/CAM h?bridos ? estrutura dent?ria e a diferentes cimentos resinosos ap?s 24 horas de armazenamento em ?gua.

Submitted by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-04-17T14:53:43Z No. of bitstreams: 1 DIS_MARIANA_BAUER_BRONSTRUP_COMPLETO.pdf: 1446600 bytes, checksum: b81291e51e70d36c91cb4f880a63dd0e (MD5) / Made available in DSpace on 2017-04-17T14:53:43Z (GMT). No. of bitstreams: 1 DIS_MARIANA_BAUER_BRONSTRUP_COMPLETO.pdf: 1446600 bytes, checksum: b81291e51e70d36c91cb4f880a63dd0e (MD5) Previous issue date: 2016-12-21 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Patients with cleft lip and palate (CLP) and edentulous patients are considered physically mutilated individuals. Although with different tooth loss etiologies, they both have functional and aesthetic limitations. Dental loss is associated with poor quality of life (QoL) because of decreased self-esteem and psychosocial function. The objective of this study was to evaluate, through a quantitative and qualitative analysis, the impact of oral rehabilitation on the quality of life of edentulous patients and CLP subjects. A convenience sample of 46 adult patients, composed of 15 men and 31 women, was divided into two groups: (G_CLP) with CLP (n=20) and (G_PTFI) with implant-supported fixed total prosthesis (n=20). OHIP-14 was used for quantitative QoL analysis. Data were analyzed by the additive method and Kruskal Wallis test. Patients with poor QoL scores in both groups (n=9) participated of qualitative phase performed with semi-structured interviews. The OHIP-14 results showed a significant difference between the two groups (p <0.05). G_PTFI had worse QoL than G_FLP in all dimensions. In the qualitative analysis, before the oral rehabilitation of G_PTFI, the most affected dimensions were physical pain and physical incapacity. For G_CLP, the most affected dimensions were self-esteem and functional limitation. After the prosthetic treatment, G_CLP reported a considerable improvement in the psychosocial functions and a high degree of satisfaction with the treatment, although they also perceived a decrease in physical functions. G_PTFI reported improvement in all dimensions but were not satisfied with the overall treatment and aesthetics. OHIP-14 shows that QoL is affected by oral conditions but cannot detect the origin and magnitude of the problems by itself. The qualitative study provides a deeper and comprehensive interview understanding of QoL considering the individual aspects of each patient. / Pacientes portadores de fissura labiopalatina (FLP) e sujeitos edentados s?o considerados indiv?duos fisicamente mutilados, que, embora com etiologias de perda dent?ria diferentes, possuem limita??es funcionais e est?ticas. A perda dent?ria est? associada ? baixa qualidade de vida (QV), pois diminui a autoestima e a fun??o psicossocial do indiv?duo. O objetivo desse estudo foi avaliar, atrav?s de uma an?lise quantitativa e qualitativa, o impacto da reabilita??o bucal na qualidade de vida de pacientes ed?ntulos e de portadores de FLP em sujeitos adultos. Uma amostra de conveni?ncia de 46 participantes adultos, composto por 15 homens e 31 mulheres, foi dividida em dois grupos: (G_FLP) fissuras labiopalatinas (n=20); (G_PTFI) pr?tese total fixa implantossuportada (n=26). O instrumento OHIP-14 foi usado para a obten??o de dados quantitativos para estudo da QV. A an?lise de dados foi feita pelo m?todo aditivo e pelo teste Kruskal Wallis. Participantes com escore relativo ? baixa QV nos dois grupos (n=9) participaram da fase qualitativa realizada com entrevistas semiestruturadas. Nos resultados do OHIP-14 houve diferen?a significativa entre os dois grupos (p<0,05). O grupo G_PTFI teve QV mais afetada em compara??o com G_FLP em todas as dimens?es. Na an?lise qualitativa, antes das reabilita??es, as dimens?es mais afetadas foram dor f?sica e incapacidade f?sica para o G_PTFI; j? as dimens?es mais afetadas para o G_CLP foi autoestima e limita??o funcional. Ap?s o tratamento prot?tico os participantes do G_CLP passaram a relatar melhora consider?vel nas fun??es psicossociais e alto grau de satisfa??o com o tratamento, embora percebessem piora nas fun??es f?sicas. J? o G_PTFI obteve melhoras em todas as dimens?es, por?m eram menos satisfeitos com o tratamento e com a est?tica. Embora OHIP-14 identifique que a QV seja afetada pelas condi??es bucais, isoladamente ele n?o detecta a origem e a magnitude dos problemas. Um estudo qualitativo proporciona um entendimento mais profundo e integrado da QV considerando aspectos individuais do paciente.

Submitted by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-05-04T17:09:42Z No. of bitstreams: 1 DIS_FERNANDO_JOSE_FAVERO_COMPLETO.pdf: 1168551 bytes, checksum: d6327cdbdba18fcf79f78efc0806726a (MD5) / Made available in DSpace on 2017-05-04T17:09:42Z (GMT). No. of bitstreams: 1 DIS_FERNANDO_JOSE_FAVERO_COMPLETO.pdf: 1168551 bytes, checksum: d6327cdbdba18fcf79f78efc0806726a (MD5) Previous issue date: 2013-03-01 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Objectives: 1) To assess the fracture strength of cavity preparations, directly restored with composite resin, with and without the presence of fiberglass posts with different diameters; 2) to assess the fracture pattern of cavity preparations, restored or not, with or without the presence of fiberglass posts with different diameters. Materials and Methods: Eighty-four extracted third molars were embedded in acrylic resin and divided into 6 groups (n = 14 per group): healthy (H); cavity preparation (P); cavity preparation + endodontic treatment (PE); PE + composite resin (R); PE + R + 2 horizontally transfixed fiberglass posts 1.1 mm in diameter (PERP1); PE + R + 2 fiberglass posts 1.5 mm in diameter (PERP2). The MOD cavity preparations were standardized with their width corresponding to 2/3 of the buccolingual distance and occlusogingival depth of 4 mm, with 2 mm remaining above the cementoenamel junction. Endodontic treatments were performed in the PE, R, PERP1 and PERP2 groups. The buccal surface received two demarcations to create orifices for placement of the PERP1 and PERP2 posts. Once the fiberglass posts were placed, the teeth were restored with composite resin. In group R, only composite resin was used. After 24 h, the teeth were subjected to the fracture toughness test on a universal testing machine EMIC DL ? 2000. A 10KN load cell and crosshead speed of 1 mm/min were used until fracture occurred. After testing, the teeth were inspected for the type of fracture classified as: pulpal floor fracture (AP) or cuspal fracture (CP). Results: The data were subjected to ANOVA and Tukey?s test (P<0.05%), demonstrating a statistical difference between groups: H 3,830NA; P 778ND; PE 572.93ND; R 1,782NC; PERP1 2,988NB; PERP2 3,100NAB. The fracture pattern was similar between the tested groups, showing 50% of fracture for cusps and pulpal floor. Conclusions: The use of 2 fiberglass posts with different diameters, restored with composite resin, recovered around 80% of the fracture strength of a healthy tooth. / Objetivos: 1) avaliar a resist?ncia ? fratura dos preparos cavit?rios, restaurados com resina composta de forma direta, com e sem a presen?a de pinos de fibra de vidro de di?metros diferentes; 2) avaliar o padr?o de fratura dos preparos cavit?rios, restaurados ou n?o, com ou sem a presen?a dos pinos de fibra de vidro de di?metros diferentes. Materiais e M?todos: Oitenta e quatro terceiros molares extra?dos foram embutidos em resina acr?lica e divididos em 6 grupos (n=14 por grupo): h?gidos (H); preparo cavit?rio (P); preparo cavit?rio + tratamento endod?ntico (PE); PE + resina composta (R); PE + R + 2 pinos de fibra de vidro de 1,1 mm de di?metro transfixados horizontalmente (PERP1); PE + R + 2 pinos de fibra de vidro com 1,5 mm de di?metro (PERP2). Os preparos cavit?rios MOD foram padronizados com largura 2/3 da dist?ncia vest?bulo-lingual e profundidade ocluso-gengival de 4mm permanecendo 2mm acima do limite amelo-cement?rio. Foram realizados tratamentos endod?nticos nos grupos PE, R, PERP1 e PERP2. A face vestibular recebeu duas demarca??es para realizar os orif?cios para transfixar os pinos de PERP1 e PERP2. Inseridos os pinos de fibra os dentes foram restaurados com resina composta. No grupo R apenas resina composta foi utilizada. Ap?s 24 h os dentes foram submetidos ao teste de resist?ncia ? fratura em uma m?quina de ensaio universal EMIC DL ? 2000. A c?lula de carga de 10KN e velocidade de 1mm/min foi utilizada at? que a fratura ocorresse. Ap?s realiza??o dos ensaios, os dentes foram inspecionados quanto ao tipo de fratura classificada em: Fratura em assoalho pulpar (AP) ou em C?spide (CP). Resultados: Os dados foram submetidos ? ANOVA e Tukey(P<0.05%) demonstrando diferen?a estat?stica entre os grupos: H 3.830NA; P 778ND; PE 572,93ND; R 1.782NC; PERP1 2.988NB; PERP2 3.100NAB. O padr?o de fratura foi similar entre os grupos testados. Conclus?es: A utiliza??o de dois pinos de fibra de vidro com di?metros diferentes e restaurados com resina composta recuperou ao redor de 80% da resist?ncia ? fratura de um dente h?gido.

Submitted by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-05-23T17:19:03Z No. of bitstreams: 1 DIS_BIANCA_MORO_CORREA_PARCIAL.pdf: 139620 bytes, checksum: 7b6664e8dedb350b29c7a7898c664250 (MD5) / Made available in DSpace on 2017-05-23T17:19:03Z (GMT). No. of bitstreams: 1 DIS_BIANCA_MORO_CORREA_PARCIAL.pdf: 139620 bytes, checksum: 7b6664e8dedb350b29c7a7898c664250 (MD5) Previous issue date: 2017-01-19 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Objectives: The aims of this study were to evaluate the elastic modulus and the monomer conversion of self- etching adhesives (Single Bond Universal and Clearfil SE Bond) and two- steps etch-and-rinse adhesives (primer + adhesive in the same bottle, Adper Single Bond 2 and Gluma 2Bond). The null hypothesis was that two-step adhesive systems will have higher degree of monomer conversion and a higher elastic modulus than the self-etching ones. Materials and methods: On dentin disks obtained from 10 extracted third molars were applied self- etching and etch-and-rinse adhesive systems according to manufacturer's instructions and light cured by a LED light. Right after, the specimens were submitted to elastic modulus by atomic force with 50g load for 10s. The degree of conversion of the adhesives was calculated by Fourier Transform Infrared Spectroscopy (FTIR). Results: The Single Bond 2 adhesive system presented the highest monomer conversion result (88%) followed by Universal Single Bond (79%), Gluma 2Bond (71%) and Clearfil SE Bond (69%). The results for elastic modulus (MPa) were (means followed by the same letter did not present statistical difference for Tukey (p?0,05)): Single Bond 2, 2319 (A); Single Bond Universal, 2051 (AB); Gluma, 2038 (AB); Clearfil SE Bond, 1788 (B). Conclusion: lt is not possible to infer that, as a rule, conventional adhesives systems with combined primer and adhesives will have a better performance in terms of the degree of monomer conversion as well as modulus of elasticity when compared to self-etching agents. / Objetivos: Este trabalho teve por objetivos avaliar o m?dulo de elasticidade e a taxa de convers?o de mon?meros de sistemas adesivos autocondicionantes (Single Bond Universal e Clearlil SE Bond) e convencionas de dois passos (primer+adesivo no mesmo frasco, Adper Single Bond 2 e Gluma 2Bond). A hip?tese inicial foi que os sistemas adesivos de dois passos ter?o maior grau de convers?o de mon?meros e maior m?dulo de elasticidade que os autocondicionantes. Materiais e m?todos: sobre discos de dentina obtidos a partir de 10 molares extra?dos foram aplicados os sistemas adesivos de condicionamento ?cido total e os autocondicionantes de acordo com a recomenda??o dos fabricantes de cada material e fotoativados com luz LED. Ap?s, os corpos de prova foram submetidos ? medi??o de m?dulo de elasticidade por for?a at?mica com carga de 50g pelo tempo de 10s. O grau de convers?o dos adesivos foi calculado usando espectroscopia por infravermelho (FTIR). Resultados: O sistema adesivo Single Bond 2 apresentou o maior resultado de convers?o de mon?meros (88%) seguido do Single Bond Universal (79%), Gluma (71%) e Cleartil SE Bond (69%). Os resultados para o m?dulo de elasticidade (MPa) foram (m?dias seguidas de mesma letra n?o apresentam diferen?a estat?stica para Tukey (p?0,05)): Single Bond 2, 2319(A); Single Bond Universal, 2051(AB); Gluma, 2038(AB); Clearfil SE Bond, 1788(B). Conclus?o: N?o ? poss?vel inferir que via de regra pelo fato de serem os sistemas adesivos convencionais com primer e adesivos combinados ter?o um melhor desempenho quanto ao grau de convers?o de mon?meros bem como m?dulo de elasticidade quando comparados aos autocondicionantes.

Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2017-07-21T12:36:20Z No. of bitstreams: 1 BERNARDO_ALIEVI_CAMARGO_TES.pdf: 559988 bytes, checksum: 40cdf084884d3c3ac79d29f4a2c50aa7 (MD5) / Rejected by Caroline Xavier (caroline.xavier@pucrs.br), reason: Devolvido devido a diferen?a de entre o t?tulo da capa/folha de rosto, e o t?tulo da ficha catalogr?fica. on 2017-07-28T20:26:46Z (GMT) / Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2017-08-10T16:44:36Z No. of bitstreams: 1 BERNARDO_ALIEVI_CAMARGO_TES.pdf: 1292617 bytes, checksum: 385bbcc10f09c8db9f890c3f549d927e (MD5) / Approved for entry into archive by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-08-11T21:10:19Z (GMT) No. of bitstreams: 1 BERNARDO_ALIEVI_CAMARGO_TES.pdf: 1292617 bytes, checksum: 385bbcc10f09c8db9f890c3f549d927e (MD5) / Made available in DSpace on 2017-08-11T21:12:31Z (GMT). No. of bitstreams: 1 BERNARDO_ALIEVI_CAMARGO_TES.pdf: 1292617 bytes, checksum: 385bbcc10f09c8db9f890c3f549d927e (MD5) Previous issue date: 2017-05-11 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The objectives of this study was to evaluate the marginal bone loss in distal implants adjacent to the prosthetic cantilever in complete fixed complete dentures implantossuported (FCDIs) and the possible correlation of bone loss with prosthetic cantilever extension and mesio-distal inclination of the distal implant. Thirty patients (9 men; 21 women) (N=62 distal implants) were followed, with 25 in maxilla and 37 in the mand?ble, at the PUCRS college of dentistry, after 1 and 3 years of prosthesis installation. The prosthetic cantilever measurement was performed during the treatment rehabilitation and the mesio-distal inclination of the most distal implants was obtained with computed tomography (CBCT), intraoral digital radiographs of the distal implants were obtained with customized devices at baseline, 1 and 3 years after prostheses installation. The mean bone loss after 1 year was 0,23?0,36mm after 1 and 3 years was 0,28?0,41mm and after 3 years was 0,35?0,49mm, the mean cantilever extension was 9.91?5.98 and the mean inclination of the implants was 8.68?5.97 in the mesial and 6.46?5.58 in the distal side. There was no statistical correlation between marginal bone loss, cantilever extension and mesiodistal inclination of the most distal implant, after one year of follow-up, where the data were analyzed using Spearman's correlation coefficient (?=5%). It can be concluded that the extension of the distal cantilever and the mesio-distal inclination of the implant in FCDIs not showed relation with marginal bone loss in the most distal implant adjacent to the cantilever. / Este estudo tem como objetivos avaliar a perda ?ssea marginal em implantes distais adjacentes ao cantilever prot?tico em pr?teses totais fixas implantossuportadas (PTFIs) e a poss?vel correla??o da perda ?ssea com extens?o de cantilever prot?tico e inclina??o m?sio-distal do implante distal. Foram acompanhados 30 pacientes (9 homens; 21 mulheres) com 62 implantes distais, sendo 25 na maxila e 37 na mand?bula, colocados na Faculdade de Odontologia da PUCRS, ap?s 1 e 3 anos da sua instala??o da pr?tese. A medi??o do cantilever prot?tico foi realizada durante o tratamento reabilitador e a inclina??o m?sio-distal dos implantes foi obtida com tomografias computadorizadas (CBCT). Radiografias intrabucais digitais dos implantes mais distais foram obtidas com posicionadores customizados ap?s a instala??o das pr?teses (baseline), 1 e 3 anos ap?s o t?rmino do tratamento. A perda ?ssea m?dia ap?s 1 ano foi de 0,23?0,36mm, entre o primeiro e terceiro ano foi 0,28?0,41mm e acumulada durante 3 anos foi 0,35?0,49mm, a extens?o de cantilever m?dia foi 9,91?5,98mm e a inclina??o m?dia dos implantes foi 8,68?5,97 na mesial e 6,46?5,58 na distal. N?o houve correla??o estat?stica entre perda ?ssea marginal, extens?o de cantilever prot?tico e inclina??o m?sio-distal do implante mais distal, durante o per?odo de acompanhamento, onde os dados foram analisados com coeficiente de correla??o de Spearman (? = 5%). Pode-se concluir que a extens?o do cantilever para distal e a inclina??o m?sio-distal dos implantes distais em PTFIs n?o apresentaram rela??o com a perda ?ssea marginal do implante mais distal, adjacente ao cantilever prot?tico.

Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2017-08-29T19:45:31Z No. of bitstreams: 1 FABIANE_AZEREDO_TES.pdf: 3598342 bytes, checksum: 84ac81263b072eecf7c0a9a8c7903bb2 (MD5) / Approved for entry into archive by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-09-11T14:29:24Z (GMT) No. of bitstreams: 1 FABIANE_AZEREDO_TES.pdf: 3598342 bytes, checksum: 84ac81263b072eecf7c0a9a8c7903bb2 (MD5) / Made available in DSpace on 2017-09-11T14:31:55Z (GMT). No. of bitstreams: 1 FABIANE_AZEREDO_TES.pdf: 3598342 bytes, checksum: 84ac81263b072eecf7c0a9a8c7903bb2 (MD5) Previous issue date: 2017-07-11 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The objectives of this study were to evaluate two types of rare craniofacial and dento-skeletal anomalies: hemifacial microsomia (HFM) and primary of failure eruption (PFE) of the permanent teeth. A literature review addressed to the three-dimensional evaluation methods of mandibular asymmetries in subjects with HFM, using conventional computed tomography (CT) and cone beam (CBCT) was conducted (Paper 1). CBCT data of 14 individuals with HFM and 35 subjects without HFM were selected and mandibular dimensions were evaluated and compared. Cephalometric landmarks were identified in the multiplanar images and panoramic reconstructions, and linear and angular measurements were performed for comparison between the right and left sides or affected and nonaffected sides of the mandible. InVivo Dental Software (Anatomage, San Jose, CA) was used in this evaluation. All variables showed a significant difference between the affected and non-affected side of the mandible in the HFM group, except the mandibular length, that presented similar dimensions on both sides. In the comparison between HFM and control groups, the angular measurements were significantly higher on the affected side and the mandibular ramus length on the non-affected side of HFM individuals was higher than in the control group. This type of growth pattern may be associated with bone compensations in the mandible of HFM individuals (Paper 2). In the study about rare dento-skeletal malformations, different approaches for the orthodontic treatment in adults and children with PFE were presented (Paper 3). Depending on the condition severity, the impact on the functional and aesthetic aspects in affected individuals can be significant and difficult to treat. / O objetivo deste trabalho foi estudar dois tipos de anomalias craniofacias e altera??es dento-esqueletais raras: microssomia hemifacial (MHF) e falhas de erup??o prim?ria (FEP) dos dentes permanentes. Foi realizada uma revis?o de literatura, que abordou os m?todos de avalia??o tridimensional de assimetrias mandibulares em indiv?duos com MHF, por meio de tomografia computadorizada convencional e cone beam (TCCB) (artigo 1). Exames de TCCB de 14 indiv?duos com MHF e de 35 sem MHF foram selecionadas e as dimens?es mandibulares foram avaliadas e comparadas. Pontos cefalom?tricos foram localizados nas imagens multiplanares e reconstru??es panor?micas, sobre as quais medidas lineares e angulares foram realizadas para compara??o entre os lados direito e esquerdo ou lados afetado ou n?o da mand?bula. O software InVivo Dental (Anatomage, San Jose, CA) foi utilizado para esta avalia??o. Todas as vari?ves apresentaram diferen?a significativa entre o lado afetado e n?o afetado da mand?bula no grupo MFH, exceto o comprimento mandibular, que apresentou dimens?es semelhantes em ambos os lados. Na compara??o entre os grupos MHF e controle, as medidas angulares foram significativamente maiores no lado afetado e o comprimento do ramo mandibular do lado n?o afetado pela MHF foi maior do que no grupo controle. Este tipo de padr?o de crescimento pode estar associado a compensa??es ?sseas na mand?bula de indiv?duos com MHF (artigo 2). No estudo que abordou altera??es dento-esqueletais raras, foram apresentadas diferentes abordagens para tratamento ortod?ntico das FEP em adultos e crian?as (artigo 3). Deformidades faciais e dento-esqueletais raras podem promover altera??es anat?micas complexas em diferentes estruturas craniofaciais. Dependendo da severidade da condi??o, o impacto nos aspectos funcionais e est?ticos dos indiv?duos acometidos pode ser significativo e de dif?cil tratamento.

Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2017-10-03T18:59:24Z No. of bitstreams: 1 JOAO_LOPES_BONDAN_TES.pdf: 2172429 bytes, checksum: ffea0ba74b477c238faf42ea29d200db (MD5) / Rejected by Caroline Xavier (caroline.xavier@pucrs.br), reason: Devolvido devido ? falta de capa institucional no arquivo PDF. on 2017-10-04T13:38:51Z (GMT) / Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2017-10-05T17:15:31Z No. of bitstreams: 1 JOAO_LOPES_BONDAN_TES.pdf: 2360015 bytes, checksum: b0622efe2634c60233691e20bf7f7283 (MD5) / Approved for entry into archive by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-10-06T12:13:53Z (GMT) No. of bitstreams: 1 JOAO_LOPES_BONDAN_TES.pdf: 2360015 bytes, checksum: b0622efe2634c60233691e20bf7f7283 (MD5) / Made available in DSpace on 2017-10-06T12:16:18Z (GMT). No. of bitstreams: 1 JOAO_LOPES_BONDAN_TES.pdf: 2360015 bytes, checksum: b0622efe2634c60233691e20bf7f7283 (MD5) Previous issue date: 2017-09-01 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The aim of this study was to analyze both the adaptation conformity of switching platform prosthetic components and their behavior in fatigue mechanical tests. The subject was split into two manuscripts according to the scope of two specific journals in the area of oral rehabilitation. The manuscript 1 presents a literature review that enlightened concepts related to the usage of the switching platform and its biological benefits demonstrated in the literature. However, factors associated with the biomechanical stability provided by this new concept have shown to be a coarsely explored area by science. Thus, such factors need to be better understood and confirmed by studies evaluating biomechanical issues of this platform. After demonstrating this shortage in the literature review, a laboratory study started, aiming at responding questions linked to the long term prosthetic stability. The manuscript 2 assessed the adaptation conformity of switching components confronted to mechanical cycling tests. The methodology was based on 40 prosthetic components for unity rehabilitations on implants standard HE 4.1 RP, being divided in four groups: 10 components UCLA 4.1 mm (group UC 4.1), 10 components UCLA 3.6 mm (group UC 3.6) , 10 components type conic abutment 4.1 mm (group AC 4.1) and 10 conic abutment 3.6 mm (group AC 3.6) on the respective implant standard RP HE 4.1 mm. The groups have been evaluated by Energy Dispersive Spectroscopy (EDS) to confirm the manufacture standard of the samples. Scanning electronic microscopy (SEM) was used to evaluate the adaptation in the vertical (FV) and horizontal (DH) directions. For the statistical analysis of the FV data, Kruskal-wallis and Crosstabs were used. One-way analysis of variance (ANOVA) and Tukey (5%) were used for the DH data. The four groups of components (UC 4.1, UC 3.6, AC 4.1, AC 3.6 ) were prepared according to the ISO 14801: 2007 standard and submitted to 1,000,000 cycles, with a load of 100 N and frequency of 1 Hz in a universal fatigue testing machine. Results indicated conformity of adaptation (FV) among components varying from 70% to 90%. Concerning DH, the two groups of switching components (UC 3.6 and AC 3.6) presented a negative gap of 7.07% and 5.36% respectively in relation to the regular platform, while the RP groups (UC 4.1 and AC 4.1) presented a negative gap of 1.21% and 0% (p?0.05). The loss of torque after the cycling test were: 25% (UC 4.1), 39% (UC 3.6), 38% (AC 4.1) and 51% (AC 3.6), (p? 0.01). Hence, the result of the present study indicate that the switching platform components present a favorable short-term biological behavior according to the literature, but limited biomechanical behavior. In adaptation factor, there is a strong degree of precision in almost all samples in terms of FV. DH is noticed in all groups. It is also noticeable that in the platform switching groups the loss of torque after mechanical cycling test was larger. / O estudo objetivou analisar a conformidade de adapta??o de componentes prot?ticos de padr?o switching e o comportamento dos mesmos frente a teste mec?nico de fadiga, dispostos em dois manuscritos de acordo com a norma e perfil de publica??o de duas revistas espec?ficas da ?rea de reabilita??o oral. No manuscrito 1 foi realizada uma revis?o liter?ria, que elucidou conceitos relacionados ? utiliza??o da filosofia switching e seus benef?cios biol?gicos evidenciados pela literatura. No entanto, fatores relacionados com estabilidade biomec?nica associados a esse novo conceito demonstraram-se constituir uma tem?tica pouco explorada e evidenciada pela ci?ncia, necessitando, serem melhor compreendidos e confirmados por estudos que avaliem quest?es biomec?nicas sobre esta filosofia. Atrav?s dessa car?ncia demonstrada pela revis?o liter?ria, passou-se a etapa de estudo laboratorial, objetivando buscar respostas a quest?es envolvendo a estabilidade prot?tica de longo prazo. O manuscrito 2 avaliou a conformidade de adapta??o de componentes switching e seu comportamento frente a testes de ciclagem mec?nica, tendo como metodologia o uso de 40 componentes prot?ticos para reabilita??es unit?rias sobre implantes padr?o Hex?gono Externo 4,1 Plataforma Regular, sendo divididos em quatro grupos: 10 componentes UCLA de 4,1 mm (grupo UC 4,1), 10 componentes UCLA de 3,6 mm (grupo UC 3,6) , 10 componentes tipo pilares c?nicos de 4,1 mm (grupo AC 4,1) e 10 pilares c?nicos de 3,6 mm (grupo AC 3,6) sobre referido implante padr?o RP Hex?gono Externo 4,1 mm. Os grupos foram avaliados por Espectroscopia de Energia Dispersiva (EDS) para confirmar o padr?o de manufatura das amostras, e tamb?m comparada a adapta??o com aux?lio de Microscopia Eletr?nica de Varredura (MEV) quanto a Fenda Vertical (FV) e Discrep?ncia Horizontal (DH). Para a an?lise estat?stica dos dados de FV, aplicou-se os testes de Kruskal-wallis e Crosstabs, e para DH o procedimento de an?lise de Vari?ncia (Anova-Oneway) e de Tukey, ao n?vel de signific?ncia de 5%. Os quatro grupos de componentes (UC 4,1, UC 3,6, AC 4,1, AC 3,6 ) foram preparados conforme norma ISO 14801: 2007 e submetidos ? 1.000.000 de ciclos, com carga de 100 N e frequ?ncia de 1 Hz em m?quina de simula??o de fadiga. Resultados indicaram conformidade de adapta??o de fenda entre componentes variando de 70% a 90%. Quanto ? DH os dois grupos com componentes Switching (UC 3,6 e AC 3,6) apresentaram degrau negativo de 7,07 % e 5,36% respectivamente em rela??o a plataforma regular, enquanto os grupos de padr?o regular (UC 4,1 e AC 4,1) degrau negativo de 1,21% e 0 % (p?0,05). Em rela??o ? perda de torque ap?s a ciclagem foram obtidos os graus percentuais em cada grupo de 25% (UC 4,1), 39% (UC 3,6), 38% (AC 4,1) e 51% (AC 3,6), (p? 0,01). Desse modo, resultados do presente estudo indicam que os componentes com padr?o switching apresentam-se com comportamento biol?gico favor?vel de curto prazo de acordo com a literatura consultada, mas comportamento biomec?nico limitado. Em fator de adapta??o h? um grau de marcante precis?o em quase todas as amostras em termos de FV. A DH ? notada em maior ou menor grau, tanto em amostras regulares, quanto em padr?o switching. Observou-se que quanto maior o degrau negativo de discrep?ncia horizontal, maior ? o grau de perda de torque ap?s a ciclagem mec?nica. Foi observada tamb?m uma tend?ncia de que quanto mais marcada a aplica??o do conceito switching, maior a perda de torque associada.

Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2018-03-15T18:26:06Z No. of bitstreams: 1 MARCELO_MATOS_ROCHA_DIS.pdf: 2694699 bytes, checksum: b35320c3e1bad1e5215967015213d4c2 (MD5) / Approved for entry into archive by Tatiana Lopes (tatiana.lopes@pucrs.br) on 2018-03-28T12:16:11Z (GMT) No. of bitstreams: 1 MARCELO_MATOS_ROCHA_DIS.pdf: 2694699 bytes, checksum: b35320c3e1bad1e5215967015213d4c2 (MD5) / Made available in DSpace on 2018-03-28T12:29:33Z (GMT). No. of bitstreams: 1 MARCELO_MATOS_ROCHA_DIS.pdf: 2694699 bytes, checksum: b35320c3e1bad1e5215967015213d4c2 (MD5) Previous issue date: 2018-01-12 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Bisphosphonates have been associated with medication-related osteonecrosis of the jaw (MRONJ), a disorder that has some risk factors such as surgical interventions in the jaw bones, especially tooth extractions. On the other hand, xenogeneic grafts have been widely used to fill the alveolar socket after tooth extraction, with clinical evidences of improving local conditions of the surgical bed for oral rehabilitation. The aim of this study was to investigate the effect of combined bisphosphonate and the xenogeneic graft Bio-Oss? Collagen on alveolar bone repair after tooth extraction. Sixty rats were allocated into five groups according to the treatment received: zoledronic acid (group 1) and alendronate (group 2) both with xenogeneic graft; zoledronic acid (group 3) and alendronate (group 4) both without xenogeneic graft; and control (group 5). All animals were subjected to tooth extractions, and maxillae were dissected and macro- and microscopically analyzed. Frequency of oral mucosal wounds did not significantly differ between the groups; however, these lesions were significantly smaller in the control group. The amount of fibrous connective tissue was greater in groups 2 (alendronate/Bio-Oss) and 5 (control) than in 3 (zoledronic acid) and 4 (alendronate). Group 4 showed greater amounts of vital bone than did groups 1 (zoledronic acid/Bio-Oss), 3 and 5. The amounts of non-vital bone were greater in the zoledronic acid groups (1 and 3), where non-vital bone was less in group 1 than 3. Group 3 showed more inflammatory infiltrate than groups 2, 4 and 5. There were greater amounts of microbial colonies in group 3. Inflammatory infiltrate and microbial colonies were negatively correlated to vital bone and positively correlated to non-vital bone. Inflammatory infiltrate and microbial colonies were positively correlated to each other. Conclusion: Post-extraction socket filling with Bio-Oss? Collagen did not prevent the occurrence of non-vital bone and infection, but it did lower the extent of these variables in rats under treatment with zoledronic acid. / Os bisfosfonatos t?m sido associados ? ocorr?ncia de osteonecrose maxilar (MRONJ, medication-related osteonecrosis of the jaw), condi??o que tem, entre os fatores de risco para sua ocorr?ncia, as interven??es cir?rgicas dos ossos maxilares, principalmente as exodontias. Por outro lado, o uso de xenoenxerto para preenchimento alveolar ap?s exodontia tornou-se procedimento frequente, com evid?ncias cl?nicas de sua capacidade em melhorar as condi??es locais do s?tio cir?rgico com vistas ? reabilita??o oral. O presente estudo teve por objetivo investigar o efeito do uso combinado de bisfosfonato e enxerto xen?geno (Bio-Oss?Collagen) no reparo ?sseo alveolar ap?s exodontia. Sessenta ratos foram distribu?dos em cinco grupos de acordo com o tratamento recebido: ?cido zoledr?nico (grupo 1) e alendronato (grupo 2), ambos com xenoenxerto; ?cido zoledr?nico (grupo 3) e alendronato (grupo 4), ambos sem xenoenxerto; e grupo-controle (grupo 5). Todos os animais foram submetidos a exodontias, as maxilas foram dissecadas e analisadas por meio de exame macro- e microsc?pico. A frequ?ncia de les?o da mucosa oral n?o diferiu significativamente entre os grupos; entretanto essas les?es foram significativamente menores no grupo-controle. A preval?ncia de tecido conjuntivo fibroso foi maior nos grupos 2 (alendronato/Bio-Oss) e 5 (controle) do que nos grupos 3 (?cido zoledr?nico) e 4 (alendronato). O grupo 4 (alendronato) teve maior quantidade de osso vital do que os grupos 1 (?cido zoledr?nico/Bio-Oss), 3 (?cido zoledr?nico) e controle. A quantidade de osso n?o-vital foi maior nos grupos ?cido zoledr?nico com e sem Bio-Oss (1 and 3), sendo que, ao comparar-se esses dois grupos entre si, essa vari?vel foi maior no grupo 3. O grupo 3 exibiu mais infiltrado inflamat?rio do que os grupos 2, 4 e 5 e maior quantidade de col?nias microbianas do que os demais grupos. Infiltrado inflamat?rio e col?nias microbianas tiveram correla??o negativa com osso vital e positiva com osso n?o-vital. Infiltrado inflamat?rio e col?nias microbianas exibiram correla??o positiva entre si. Conclus?o: O preenchimento do alv?olo p?s-exodontia com Bio-Oss? Collagen n?o evitou a ocorr?ncia de osso n?o-vital e infec??o, mas foi capaz de diminuir a intensidade dessas vari?veis nos ratos sob tratamento com ?cido zoledr?nico.

Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2018-03-19T17:50:17Z No. of bitstreams: 1 TAMARA_PALUDO_DIS.pdf: 786437 bytes, checksum: 24d142989a1f4e1aac8bb4a9d2a1548c (MD5) / Approved for entry into archive by Tatiana Lopes (tatiana.lopes@pucrs.br) on 2018-04-04T11:42:36Z (GMT) No. of bitstreams: 1 TAMARA_PALUDO_DIS.pdf: 786437 bytes, checksum: 24d142989a1f4e1aac8bb4a9d2a1548c (MD5) / Made available in DSpace on 2018-04-04T11:50:01Z (GMT). No. of bitstreams: 1 TAMARA_PALUDO_DIS.pdf: 786437 bytes, checksum: 24d142989a1f4e1aac8bb4a9d2a1548c (MD5) Previous issue date: 2018-01-10 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / (Artigo 1 Effect of a collagen stabilizing acid conditioner on adhesion to enamel and dentin) The aim was to evaluate the effect of different concentrations of phosphoric acid with grape seed extract (GSE) on the enamel acid etching, on the immediate bond strength to enamel, and on the bond strength to dentin after 12 months storage. Three different phosphoric acid formulations with GSE were obtained: GSE5 - 5% phosphoric acid + 20% ethanol + 2% GSE; GSE10 -10% phosphoric acid + 20% ethanol + 2% GSE; GSE20 - 20% phosphoric acid + 20% ethanol + 2% GSE; GC (control) - 37% phosphoric acid. The enamel and dentin surfaces of third molars, extracted for therapeutic reasons, were etched with 37% phosphoric acid for 15 s, and with the modified acids for 30 s. The acid was rinsed, followed by application of Adper Scotchbond Multipurpose adhesive system, and a block of composite resin was built. In enamel, the etching pattern was evaluated by scanning electron microscopy (SEM) and the bond strength was evaluated by conventional tensile test. In dentin, the microtensile bond strength (?TBS) was evaluated after 24 h and 1 year of storage. SEM images showed that GSE5 caused a more superficial enamel etching. According to ANOVA and Tukey?s test, enamel bond strength did not differ significantly between GC (49.00 MPa), GSE5 (42.78 MPa), GSE10 (51.55 MPa) and GSE 20 (36.18 MPa) (p> 0.05).According to two-way ANOVA and Tukey?s test, the interaction of factors (treatment x storage time) was significant (p=0.0001). At the 24 h of storage, GC (28.43 MPa) obtained the highest ?TBS, and did not differ significantly from GSE20 (24.11 MPa). GC and GSE20 were significantly higher to the others (p<0.05).The GSE10 (17.53 MPa) and GSE5 (16.75 MPa) did not differ significantly from each other. At the 12 months of storage, there was no significant difference in ?TBS between GC (17.71 MPa), GSE5 (20.97 MPa), GSE10 (17.59 MPa) and GSE20 (18.52 MPa). Only GSE5 and GSE10 did not significantly decrease ?TBS after 12 months of storage. It was concluded that GSE5 caused a more superficial enamel etching pattern in relation to the acid concentrations at 37%, 20% and 10%. However, there was no significant difference in the bond strength to enamel among the four concentrations. GSE5 and GSE10 promoted stability of the bond strength to dentin after 12 months of storage. (Artigo 2 Effect of phosphoric acid with polyphenols on dentin collagen : Atomic force microscopy study) Objective: The aim was of this study to evaluate the effect of different concentrations of phosphoric acid with grape seed extract (GSE) on the structure of the collagen fibrils of dentin. Materials and methods: Samples (0.3 mm thickness and 8 mm diameter) of the middle third of the coronal dentin of sound human molars were obtained. Half of the dentin of each tooth was etched with phosphoric acid (5%, 10%, or 20%) for 30 s, and the other half was etched with its corresponding phosphoric acid with 2% GSE for 30 s. The dentin of each sample was observed using an Atomic Force Microscope (AFM). Results: AFM images showed that phosphoric acid at concentrations of 5%, 10% and 20% demineralized the dentin and exposed the collagen fibrils and their pattern of periodicity. Phosphoric acid at each concentration with 2% GSE changed the collagen fibril periodicity, and the collagen fibrils formed globular structures. This change was more significant in dentin treated with 5% phosphoric acid and less significant with 20% phosphoric acid. Conclusions: The use of 5% phosphoric acid with 2% GSE produced denser collagenous globular structures. This conformational change in the collagen can make it more mechanically and enzymatically resistant. / (Artigo 1 Efeito de um condicionador ?cido estabilizador de col?geno na ades?o ao esmalte e ? dentina) O objetivo foi avaliar o efeito de diferentes concentra??es de ?cido fosf?rico com extrato de semente de uva (GSE) no padr?o de condicionamento ?cido em esmalte, na resist?ncia de uni?o imediata ao esmalte e ap?s 12 meses de armazenamento em dentina. Tr?s diferentes formula??es de ?cido fosf?rico com GSE foram obtidas: GSE5 - 5% de ?cido fosf?rico + 20% de etanol + 2% de GSE; GSE10 -10% de ?cido fosf?rico + 20% de etanol + 2% de GSE; GSE20 - 20% de ?cido fosf?rico + 20% de etanol + 2% de GSE; GC (controle) - ?cido fosf?rico 37%. As superf?cies do esmalte e da dentina de dentes terceiros molares, extra?dos por raz?es terap?uticas, foram condicionadas com ?cido fosf?rico 37% por 15 s e com os ?cidos modificados por 30 s, seguido de lavagem e aplica??o do sistema adesivo Adper Scotchbond Multiuso (convencional de tr?s passos) e da constru??o de um bloco em resina composta. Em esmalte, o padr?o de condicionamento foi avaliado em microscopia eletr?nica de varredura (MEV) e a resist?ncia de uni?o foi avaliada pelo ensaio de tra??o convencional. Em dentina, a resist?ncia de uni?o ? microtra??o (R?T) foi avaliada ap?s 24 h e 12 meses de armazenamento. As imagens em MEV evidenciaram que o GSE5 causou um condicionamento mais superficial do esmalte. De acordo com ANOVA de 2 fatores e Tukey, a resist?ncia de uni?o ao esmalte n?o diferiu estatisticamente entre GC (49,00 MPa), GSE5 (42,78 MPa), GSE10 (51,55 MPa) e GSE20 (36,18 MPa) (p>0,05). De acordo com ANOVA de duas vias e Tukey, a intera??o tratamento x tempo de armazenamento foi significativa (p=0,0001). No tempo de armazenamento de 24 h, GC (28,43 MPa) obteve a maior R?T, n?o diferindo estatisticamente do grupo GSE20 (24,11 MPa), sendo ambos estatisticamente superiores aos demais (p<0,05). O grupo GSE10 (17,53 MPa) e o GSE5 (16,75 MPa) n?o diferiram estatisticamente entre si. No tempo de armazenamento de 12 meses, n?o houve diferen?a estat?stica na R?T entre o GC (17,71 MPa), GSE5 (20,97 MPa), GSE10 (17,59 MPa) e GSE20 (18,52 MPa). Apenas GSE5 e GSE10 n?o tiveram redu??o significativa da R?T ap?s 12 meses de armazenamento. Concluiu-se que o GSE5 causou um condicionamento mais superficial do esmalte em rela??o ?s concentra??es de 37%, 20% e 10%. No entanto, n?o houve diferen?a estat?stica nos valores de resist?ncia ? tra??o imediata ao esmalte entre as quatro concentra??es. GSE5 e GSE10 promoveram a estabilidade da resist?ncia de uni?o ? dentina ap?s 12 meses de armazenamento.

Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2018-06-01T13:46:10Z No. of bitstreams: 1 LIGIA_MARIA_NOGARETT_PIBERNAT_DE_CARVALHO_TES.pdf: 602746 bytes, checksum: 5e6dcc81b20622b739f9ab98624f9a66 (MD5) / Rejected by Sheila Dias (sheila.dias@pucrs.br), reason: Devolvido devido ? falta da capa institucional no arquivo em PDF. on 2018-06-11T12:41:58Z (GMT) / Submitted by PPG Odontologia (odontologia-pg@pucrs.br) on 2018-06-11T17:29:30Z No. of bitstreams: 1 LIGIA_MARIA_NOGARETT_PIBERNAT_DE_CARVALHO_TES.pdf: 1308142 bytes, checksum: e3ba9abe3c75e3384b12c1a64fbba5dd (MD5) / Approved for entry into archive by Sheila Dias (sheila.dias@pucrs.br) on 2018-06-22T11:52:39Z (GMT) No. of bitstreams: 1 LIGIA_MARIA_NOGARETT_PIBERNAT_DE_CARVALHO_TES.pdf: 1308142 bytes, checksum: e3ba9abe3c75e3384b12c1a64fbba5dd (MD5) / Made available in DSpace on 2018-06-22T12:01:25Z (GMT). No. of bitstreams: 1 LIGIA_MARIA_NOGARETT_PIBERNAT_DE_CARVALHO_TES.pdf: 1308142 bytes, checksum: e3ba9abe3c75e3384b12c1a64fbba5dd (MD5) Previous issue date: 2017-04-25 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The aim of the present study was to asses the present of Bisphenol A in dental material used on CAD/CAM block.For this In Vitro study, blocks for CAD-CAM, Lava Ultimate, Enamic and Mark II in standardized fragments containeing Bisphenol A were evaluated. Ten fragments of each block were made: n = 30, immersed in deionized water on group 1 and artificial saliva Kin Hidrat on group 2 in a light protected bottle.Stored in a culture stove for 24 hours, all samples were put in 1,5ml bottles containing 1,0ml of artificial saliva (KIN HIDRAT, PharmaKIN, S?o Paulo, Brazil ) on group 1 and deionized water on group 2, and then freezed in -80?C for 24 hours. After the 24 hour period, the samples were submitted to High Efficiency Chromatography on Toxicology and Pharmacology Institute of PUCRS as methodology described on this study.After cromatographic analysis of groups 1 and 2, the non-release of Bisphenol A was observed in all groups of samples tested. All groups and samples presented peak release of unidentified substance of different molecular weight and different breaking time than the Bisphenol A standard. Additional researches using other analysis methods are needed to examine the cumulative estrogenic effects of Bisphenol A dental materials for CAD CAM and composite resins. / O objetivo geral deste estudo foi avaliar o componente Bisfenol A presente em blocos de materiais dent?rios utilizados no sistema CAD/CAM quanto a libera??o ou n?o de Bisfenol A. Foram avaliados para a realiza??o deste estudo in vitro, blocos para CAD/CAM, Lava Ultimate, Enamic e Mark II, em fragmentos padronizados, cuja matriz de resina composta continha Bisfenol A. Foram confeccionados 10 fragmentos de cada um dos blocos: n = 30, imerso em ?gua deionizada no grupo 1 e saliva artificial KinHidrat no grupo 2 em frasco protegido da luz. Armazenadas em estufa por 24hs,todas as amostras, ap?s o periodo de 24hs, foram armazenadas em recipientes de 1,5ml contendo 1,0 ml de saliva artificial (KIN HIDRAT,PharmaKIN, S?o Paulo, Brasil ) no grupo 1 e ?gua deionizada no grupo 2 e ap?s congeladas ? - 80?C por 24hs. Decorrido o per?odo de 24h, as amostras foram submetidas a cromatografia de alta efici?ncia (HPLC) no Instituto de Toxicologia e Farmacologia da PUCRS com metodologia descrita no estudo.Ap?s an?lise cromatogr?fica dos grupos 1 e 2 observou- se a n?o libera??o de Bisfenol A em nenhum dos grupos de amostras testadas.Todos os grupos e amostras apresentaram pico de libera??o de subst?ncia n?o identificada de diferente peso molecular e diferente tempo de quebra do padr?o de Bisfenol A. Pesquisas adicionais, empregando outros m?todos de an?lise s?o necess?rias para examinar os efeitos estrog?nicos cumulativos do Bisfenol A de materiais dent?rios para CAD/CAM e resinas compostas.