The general aim of the thesis was to investigate potential differences in memory performance between participants across the adult life span with and without self-reported musculoskeletal pain. Chronic musculoskeletal pain is a major health related problem in our society. A common complaint related to chronic pain is about cognitive difficulties in attention, memory, and decision making. A number of studies have demonstrated that people with pain also perform wors on tasks measuring, for example episodic memory, semantic memory, and working memory. The present thesis aimed at replying these findings, by using a non-clinical population based sample. the potential differences in memory performance between people with and without pain were examined across the adult life span, in order to disentangle potential pain by age interactions. This was made by using both cross-sectional and longitudinal data. Study I aimed at studying differences in episodic memory performance, semantic memory performance, and implicit memory performance, between people with and without musculoskeletal pain. Differences were found for all three memory systems, but disappeared after controlling for years of formal education. In Study II an extension of the first study was made, in which performance on a range of cognitive tests were analysed. General differences were demonstrated , but yet again, years of education together with depression ruled out the effects. The most robust effects were found for word comprehension and construction ability. Finally, Study III used 5- and 10 year follow up studies to examine change over time in cognitive performance as a function of pain. The main finding from this study was that semantic memory for the oldest is impaired over time as a function of pain. An additional analysis showed similar patterns, regardless of age, for construction ability.

Introduction: Neck pain is a common problem in society and is more prevalent among women. The consequences of neck pain for the individual often include activity and participation limitations, thus affecting many dimensions of life. There is still a lack of understanding of the underlying mechanisms of the disorder and likewise of efficient rehabilitation for people with neck pain. However, coordination exercises have shown promising short-term effects. To carry this line of research forward, there is a need to improve methods for objective characterization of impairments and to investigate novel methods of rehabilitation. Aims: To characterize impairments of active cervical range of motion of the upper and lower cervical levels in women with chronic neck pain with a novel method (Study I and II) and identify the influence of head posture and movement strategies (Study II). Further, to investigate the effects of a novel method for neck coordination exercise on sensorimotor function and neck pain (study III) and the consistencies of motor variability metrics in a goal directed arm movement task to aid the design of future clinical research (Study IV). Methods: All studies were laboratory based with kinematic assessments of neck movements (Study I-III), balance (Study III) and goal directed arm movements (Study III, IV). The studies had designs that were: cross-sectional (I and II), randomized controlled trial (III) or test-retest reliability study (IV). Participants in Study I (n=135) and II (n=160) were women with chronic non-specific neck pain and healthy controls. In Study III, women with chronic non-specific neck pain (n=108) were randomized into three different individually supervised 11 week interventions. Study IV included healthy women (n=14). Results: It was found that cervical range of motion impairments in women with non-specific neck pain were direction- and level-specific; impairments were greater in extension in the upper and flexion in the lower levels of the cervical spine. The magnitude of impairments in range of motion was associated to self-ratings of functioning and health. Possible group differences in natural head posture were rejected as a cause for the direction specific effects. Neither could the effects be explained by a strategy to minimize torque in the cervical spine during movement execution. The neck coordination training was not superior to strength training (best-available) and massage treatment (sham) in improving sensorimotor functions or pain according to short-term and 6 months follow ups. The results from the study of the goal directed movement task showed that between and within-subject sizes of most motor variability metrics were too large to make the test suitable for application in clinical research. Conclusions: Women with chronic non-specific neck pain have direction- and level-specific impairments in cervical sagittal range of motion. The underlying causes of these specific impairments remains unresolved, but the direction specific impairments are not related to natural head posture. The clinical validity of the method of characterization of cervical range of motion was supported and it can be useful in future clinical research. The novel method of neck coordination exercise showed no advantages on sensorimotor functions or pain compared with best-available treatment in women with chronic non-specific neck pain. / Långvarig smärta i nacken är vanligt förekommande och orsakar både personligt lidande och stora kostnader för samhället. Långvariga nackbesvär är vanligare hos kvinnor än hos män. Det saknas kunskap om effektiva rehabiliteringsmetoder, men forskning har indikerat att träning som förbättrar nackens koordination kan vara effektivt. För att uppnå bättre rehabiliteringsresultat är det viktigt att utveckla metoder för att objektivt mäta funktionsnedsättningar och att utveckla samt utvärdera nya rehabiliteringsmetoder. Syftet med avhandlingen kan sammanfattas i tre delar: Att detaljerat mäta nedsättningar i nackens rörelseomfång hos kvinnor med långvarig nacksmärta; att utvärdera effekten av en ny metod för nackkoordinationsträning på rörelsefunktion och smärta hos kvinnor med långvarig nacksmärta; samt att utvärdera ett nytt test för att mäta precision och koordination vid målriktade armrörelser och ämnat för framtida klinisk forskning. Resultaten visade att kvinnor med långvarig nacksmärta hade specifika nedsättningar i nacken rörelseomfång; i övre nackregionen var bakåtböjning mer begränsad medan i nedre nackregionen var framåtböjning mer begränsad. Vi kunde utesluta att resultaten berodde på skillnader i huvudets normala hållning. Graden av rörelsebegränsning i nacken uppvisade samband med personernas självskattade funktion, symtom och hälsa. Nackkoordinationsträningen var inte var bättre än styrketräning eller massage för att förbättra rörelsefunktion eller för att minska smärta. Det nya testet för armrörelser var inte lämpat för kliniska studier av rörelseprecision. Slutsatserna från avhandlingsarbetet är att kvinnor med långvarig nacksmärta har begränsningar i nackens rörelseomfång vid framåt- och bakåtböjning av huvudet som är specifika vad gäller nivå i halsryggen och riktning. Att graden av rörelsebegränsning uppvisade samband med självskattad funktion, symtom och hälsa styrker testets kliniska validitet. Ytterligare forskning behövs för att förstå orsakerna bakom de specifika nedsättningarna. Nackkoordinationsträningen som utvärderades kan inte rekommenderas för kvinnor med långvarig nacksmärta eftersom korttidsuppföljning och 6-månadersuppföljning visade att träningsformen inte var bättre än styrketräning eller massage, vare sig när det gällde att förbättra sensomotorisk funktion eller att minska smärta.

This dissertation focuses on 2 parts: 1) Whether evidence-based guidelines are recognized and integrated into clinical practice in primary care and 2) Whether a university course aimed at teaching physical therapists to identify and address evidence-based psychosocial factors in primary care might change practice behaviour and patient outcome. To this end practising clinicians were surveyed and a course for physical therapists was developed.Concerning the first part, we showed that a relatively large proportion of clinicians in primary care were unfamiliar with the content of evidence-based guidelines and/or with the concept of “Red flags”. Yet, concerning the self-reported practice behaviour, the majority indicated they followed the key points in the guidelines. To enhance the impact of guidelines, interventions or tactics for teaching and implementing guidelines should include interactive education,discussion, feedback, and reminders which in research have shown to enhance knowledge,skills and change behaviour. Furthermore, the clinical applicability of the guidelines needs to be further developed. We could also show that psychosocial factors were integrated up to a certain point and that physical therapists in primary care were well aware of the importance of psychosocial risk factors, but it seemed physical therapists lack specificity about which factors are important. Physical therapists may have heard about risk factors but probably did not have a clear model or structure about how these factors work.Concerning the second part, the results showed that we, by means of a university course, managed to change attitudes and beliefs, increase knowledge, skills and competencies towards a more biopsychosocial standpoint. But despite these changes, the results did not show a behavioural change on behalf of the physical therapists or a better outcome for patients at risk of longterm pain and disability. Several possible explanations for this are discussed. First, the content of the course should be changed so it focuses more on behavioural change on behalf of the physical therapists. This would facilitate implementation of new behaviour in clinical practice and increase the likelihood that the new behaviour is maintained and thereby the possibility of improved patient outcome. Second, treating patients at risk for long-term pain and disability may also be too difficult for a single physical therapist in a clinical setting. This would imply large changes in the way patients are directed through the health care system compared to now. The main tasks of the physical therapists in primary care would then be to select patients at risk for long-term pain and disability. They would then treat the patients not at risk and refer the patients at risk for long-term pain and disability to more suitable treatment, for example CBT treatment delivered by a psychologist or multimodal treatment delivered by a team of experts.Since risk patients experience most suffering and are the most costly for the health care system, it is important they get the appropriate treatment at the earliest possible opportunity.In summary, this dissertation shows that integrating psychosocial factors in physical therapy is not an easy task.

This thesis examines two aspects of social inequalities in health with three empirical studies that are based on the Swedish Level of Living survey (LNU): The relationship between accumulated occupational class positions during adulthood and health and the class-specific nature of gender differences in health. Previous research continuously finds that there are health differences by class and gender, but less is known about the extent to which accumulated class experiences in adulthood are related to health or how gender differences vary by class. The overall conclusion in this thesis is that occupational class experiences matters for health, both as historical and current experiences. Furthermore, the results highlight the importance of taking class into consideration when examining health differences between men and women, as the mechanisms that underlie the gender gaps in health are not necessarily the same for all classes. The studies can be outlined as: Study I: Class differences in working conditions is a mechanism that underlies class inequalities in health. The working class is generally more exposed to adverse working environments than non-manual employees, and when the wear and tear of these conditions accumulate over time, the length of this exposure may contribute to class inequalities in health. Thereby, accumulated time in the working class is studied as a partial explanation for class differences in health. The results suggest that the duration of time in the working class is related to a higher probability of less than good self-rated general health (SRH), given current class position. This association was also found among individuals who were no longer in working class positions and thus show that duration of experience matters, both as current and past experience. Study II: The study addresses the research gap of class-specificity in gender health inequality and seeks to further disentangle class and gender by studying gender gaps separately by class. The results show that there are class-specific gender gaps for both SRH and musculoskeletal pain, while the gender gap in psychiatric distress appears to be more general across class. Working conditions do not explain the between-class differences in gender gaps but contribute to specific gender differences in health within classes. Study III: The labour market has changed over time and has “upgraded” the class structure while at the same time the share of women in paid employment has increased. Therefore, female health may be increasingly influenced by occupational factors, such as working conditions. This study explores the class-specific nature of gender differences and investigates musculoskeletal pain and working conditions among employed men and women within classes during a time-period that spanned more than 30 years. There were class-specific gender gaps in health throughout the period. The gender gap has increased more, and is wider, among non-manual employees compared to the working classes. This development could not be explained by changes in working conditions. / <p>At the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 2: Manuscript. Paper 3: Manuscript.</p>

Syfte: Att belysa patienters upplevelser av att leva med långvarig smärta. Bakgrund: Smärta är den vanligaste orsaken till att personer söker vård. Det är ett tillstånd som är kopplat till låg livskvalité och det är vanligt att vuxna individer lever med smärta under en längre tid. Det påverkar alla delar av en fungerande hälsorelaterad vardag. Metod: Litteraturstudien har genomförts baserat på åtta kvalitativa vetenskapliga artiklar. De inkluderade artiklarna hittades på PubMed och CINAHL. Dessa har kvalitetgranskats, analyserats och slutligen sammanställts. Resultat: Analysen resulterade i tre kategorier och åtta tillhörande underkategorier. Kategorierna är följande: Försämrad livskvalitet, Strategier för att hantera smärtan och Viktigt med stöd från omgivningen. Konklusion: Att leva med långvarig smärta bidrar till en försämrad livsvalité. Egna strategier behövs för att hantera smärtan, men det är också viktigt med stöd från omgivning och sjukvård. Litteraturstudien har betydelse för sjuksköterskan genom att öka förståelse för patienters uppleveser och därigenom också möjlighet att förbättra omvårdnaden. / Aim: The aim of this study was to describe patients´ experiences of living with chronic pain. Background: Pain is the most common cause of people seeking care. It is a condition that is linked to low quality of life and it is common for adult individuals to suffer with pain for a long period of time. It affects all parts of a functioning health-related daily life. Methods: A literature study was conducted, based on eight qualitative scientific articles. The included articles were found on PubMed and CINAHL. These have been reviewed regarding quality, analyzed and finally complied. Result: The analysis resulted in three categories and eight associated subcategories. The categories that were formed were: Deteriorated quality of life, Strategies to manage pain and Support from others is important. Conclusion: Living with chronic pain contributes to a deteriorating quality of life. Own strategies are needed to manage the pain, but support from the surrounding and healthcare is also important. This literature study may have importance for nurses to increase the understanding of patient's experiences and consequently also the opportunity to improve their care.

Introduktion: Långvarigt stillasittande och repetitivt arbete har visat på negativa kroppsliga effekter som till exempel muskuloskeletala besvär och ökad risk för hjärt-kärlsjukdomar. Som motvikt finns evidens för att variation under arbetsdagen i form av korta, aktiva pauser ger positiva effekter där så lite som två minuter styrketräning per dag räcker. Att implementera aktiva pauser är dock utmanande och flera faktorer spelar in både hos medarbetare och chefer.  Syfte: Syftet är att undersöka prevalensen av muskuloskeletal smärta före och efter implementering av aktiva styrkepauser, i form av fysisk aktivitet under arbetstid, på Klinik A. Studien ska även undersöka deltagandet och attityden till implementeringen av aktiva styrkepauser på klinik A, B och C.  Metod: Uppföljning av implementering av aktiva styrkepauser infördes på tre avdelningar på ett större sjukhus. Medarbetarna på avdelningarna fick en enkät, utformad av författarna, utskickad via mail som frågade om deltagande och attityd av implementeringen. En avdelning besvarade ytterligare en enkät om muskuloskeletal smärta. Denna enkät var en ett-årsuppföljning mellan oktober 2022 och oktober 2023.  Resultat: Resultatet från besvärsenkäten visade att muskuloskeletala besvär i nacke, axlar och övre rygg minskade efter ett år. Implementeringsenkäten visade att det var 30 av 32 som deltog i de aktiva styrkepauserna. Deltagarna hade en positiv attityd och upplevelse av implementeringen. Stöttning från chefer och starka individuella motivationsfaktorer, såsom tävlingsmoment, visade sig vara viktiga aspekter.   Konklusion: Den minskade muskuloskeletala smärtan stämmer överens med andra studier. Majoriteten av de som svarade på implementeringsenkäten deltog i de aktiva pauserna och hade en positiv attityd till de aktiva styrkepauserna. Mer forskning i olika arbetsmiljöer krävs dock för att säkerställa hur en lyckad implementering av aktiva styrkepauser ska genomföras.

Objetivo: Avaliar o uso de dispositivos eletrônicos e televisão (TV) em adolescentes saudáveis de uma escola particular da cidade de São Paulo; avaliar possíveis associações entre a presença de dor e síndromes musculoesqueléticas e o uso de dispositivos eletrônicos e TV. Métodos: Trata-se de um estudo transversal com adolescentes de uma escola particular da cidade de São Paulo. 299 adolescentes (10 a 19 anos) responderam a um questionário individual, confidencial e autoaplicável, com perguntas sobre o uso isolado e simultâneo de dispositivos eletrônicos (computadores, videogames, celular) e TV; dados demográficos; prática de atividade física e esportiva; disponibilidade, padrão de consumo, tipos de mídia utilizados e sintomas dolorosos do sistema musculoesquelético. Além da aplicação do questionário, foi realizado exame físico específico do aparelho musculoesquelético nos adolescentes que apresentavam queixas álgicas nos últimos três meses, visando à avaliação das seguintes síndromes musculoesqueléticas idiopáticas crônicas e não inflamatórias: fibromialgia juvenil, síndrome de hipermobilidade articular benigna, síndrome miofascial, tendinite, bursite, epicondilite e síndrome de dor regional complexa. Resultados: O índice de Kappa entre o pré-teste e reteste foi de 0,83. Dor musculoesquelética e síndromes musculoesqueléticas foram encontradas em 183/299 (61%) e 60/183 (33%), respectivamente. As medianas de idade [15 (10-18) versus 14 (10-18) anos, p=0,032] e os anos de escolaridade [10 (5-12) vs. 9 (5-12) anos, p=0,010] foram significantemente maiores em adolescentes com dor musculoesquelética em comparação com aqueles sem essa condição. A frequência do gênero feminino foi maior no grupo de adolescentes com dor musculoesquelética comparado ao grupo sem essa condição (59% versus 47% p=0,019), assim como as frequências do uso do telefone celular (93% contra 81%, p=0,003) e do uso simultâneo de pelo menos dois dispositivos eletrônicos (80% vs. 67%, p=0,011) foram significantemente maiores no grupo de adolescentes com dor musculoesquelética. Em relação às comparações entre os grupos com e sem síndromes musculoesqueléticas: a frequência de gênero feminino foi significantemente maior no grupo de estudantes com síndromes musculoesqueléticas (75% versus 25%, p=0,002), e os adolescentes com síndromes musculoesqueléticas apresentaram uma mediana significantemente reduzida de horas de jogos eletrônicos aos finais de semana e feriados [1,5 (0-10) vs. 3 (0-17) horas/dia, p=0,006]. Conclusões: Uma alta prevalência de dor musculoesquelética e síndromes musculoesqueléticas foi observada em estudantes adolescentes de uma escola particular. A dor musculoesquelética foi relatada em idade mais avançada, sobretudo entre as meninas e os alunos que usavam telefone celular e dispositivos eletrônicos simultaneamente. O sexo feminino e o uso reduzido de jogos eletrônicos foram associados à presença de síndromes musculoesqueléticas / Objective: To evaluate television and simultaneous electronic devices use in adolescents with musculoskeletal pain and musculoskeletal pain syndromes. Methods: A cross-sectional study was performed in 299 adolescents of a private school. All students completed a self-administered questionnaire, including: demographic data, physical activities, musculoskeletal pain symptoms, and use of simultaneous television/electronic devices (computer, internet, electronic games and cell phone). Seven musculoskeletal pain syndromes were also evaluated: juvenile fibromyalgia, benign joint hypermobility syndrome, myofascial syndrome, tendinitis, bursitis, epicondylitis and complex regional pain syndrome. Results: Inter-rater agreement between pretest and retest was 0.83. Musculoskeletal pain and musculoskeletal pain syndrome were found in 183/299 (61%) and 60/183 (33%), respectively. The median of age [15 (10-18) vs. 14 (10-18) years, p=0.032] and years of education [10 (5-12) vs. 9 (5-12) years, p=0.010] were significantly higher in adolescents with musculoskeletal pain compared to those without this condition. The frequencies of female gender (59% vs. 47%, p=0.019), cell phone use (93% vs. 81%,p=0.003) and simultaneous use of at least two electronic devices (80% vs. 67%,p=0.011) were significantly higher in the former group. Further comparisons between adolescents with and without musculoskeletal pain syndromes revealed that the frequency of female gender was significantly higher in the former group (75% vs. 25%,p=0.002), and with significantly reduced median of weekends/holidays electronic games use [1.5 (0-10) vs. 3 (0-17) hours/day, p=0.006]. Conclusions: A high prevalence of musculoskeletal pain/syndromes were observed in female adolescents. Musculoskeletal pain was mostly reported at median age of 15 years and students were using cell phone and at least two electronic devices simultaneously. Reduced electronic games use was associated with musculoskeletal pain syndromes

INTRODUÇÃO: A urbanização tem sido acompanhada por um crescente aumento no volume e na diversidade de resíduos sólidos produzidos. O reaproveitamento desses resíduos vem sendo feito desde o início do século XX, inicialmente pela figura do \"velho garrafeiro\", até que em 2003 ocorre o reconhecimento da profissão do \"catador de materiais recicláveis\" na Classificação Brasileira de Ocupações. O problema ambiental decorrente da geração e do descarte de resíduos fez com que fosse instituída a Política Nacional de Resíduos Sólidos, sendo que entre suas diretrizes há o estimulo à participação do catador na cadeia produtiva da reciclagem. Não obstante a ocorrência de avanços nas condições de trabalho dos catadores persistem exposições penosas às cargas biomecânicas, tais como esforços físicos, posições viciosas e movimentos repetitivos. Adicionalmente, a organização do processo produtivo e o modo com que os catadores desenvolvem suas tarefas, são situações que predispõem a riscos e danos à saúde. OBJETIVO: Identificar a ocorrência de dor/desconforto osteomusculares relacionados ao trabalho em catadores que atuam em cooperativas de triagem na Região Metropolitana de São Paulo. MÉTODO: Estudo transversal, com amostra constituída por 250 catadores distribuídos em quatro cooperativas, com entrevista dirigida por um instrumento de coleta de dados padronizado. RESULTADOS: Entre os catadores predominou o gênero feminino (62%), a idade entre 41-59 anos (53%), a raça negra/parda (66,4%) e abaixa escolaridade (77% com menos de oito anos de estudo). A dor/desconforto osteomuscular foi referida por 163 (65%) dos catadores, entre esses, a localização na coluna foi a mais frequente (50%), seguida dos membros superiores (45%) e membros inferiores (31%). Os resultados encontrados na análise multivariada mostraram que dor/desconforto estava associado aos meios de produção da cooperativa (p<0.000), ao fato de ter tido outra ocupação (p=0.007) e ter tido acidente de trabalho (p=0.043). CONCLUSÕES: As condições de trabalho observadas eram extremamente precárias e constituíam importante fator de risco para distúrbios osteomusculares. Catadores estão expostos à mesma posição de trabalho por longo período, posturas inadequadas, monotonia, esforço físico, repetitividade e manuseio de materiais cortantes. As condições em que desempenham suas tarefas são prováveis fatores a problemas osteomusculares / INTRODUCTION: Urbanization has been accompanied by a growing increase in the volume and diversity of solid waste produced. The practice of reusing these wastes has been carried out since the beginning of the XX century, initially by the figure of the \"bottle dealer\", up to 2003 when we had the recognition of the profession of \"recyclable materials collector\" in the Brazilian Classification of Occupations. The environmental problem caused by the production and disposal of waste led to the establishment of the National Solid Waste Policy, and among its guidelines there is an stimulus to the participation of the waste collector in the recycling chain. Despite the improvements in the working conditions of the waste collector, exposures to biomechanical loads, such as physical stresses, vicious positions and repetitive movements persist. In addition, the organization of the production process and the way in which the collectors perform their tasks are situations that predispose to risks and damages to health. OBJECTIVE: To identify the occurrence of musculoskeletal pain / discomfort related to the work of recyclable materials collector working in sorting cooperatives in the Metropolitan Region of São Paulo. METHOD: A cross-sectional study with a sample of 250 collectors distributed in four cooperatives, with an interview conducted by a standardized data collection instrument. RESULTS: Among the recyclable materials collector, the majority were women (62%), with age between 41-59 years (53%), of black / brown race (66.4%) and low education (77% with less than 8 years of schooling). Musculoskeletal pain / discomfort was reported by 163 (65%) of the recyclable materials collector, among them, the location in the spine was the most frequent (50%), followed by upper limbs (45%) and lower limbs (31%). The results found in the multivariate analysis showed that pain/discomfort was associated with the means of production of the cooperative (p < 0.000), having had another occupation (p=0.007) and having had a work accident previously (p = 0.043). CONCLUSIONS: The working conditions observed are extremely precarious and constitute an important risk factor for musculoskeletal disorders. Waste pickers are exposed to the same work position for long periods, inadequate postures, monotony, physical effort, repetitiveness and handling of sharp materials. The conditions under which they perform their tasks are likely factors to musculoskeletal problems

INTRODUÇÃO: A dor pélvica crônica não visceral constitui desafio clínico, justificável pela diversidade de estruturas presentes na pelve e pelo amplo arcabouço musculoesquelético que a envolve, sustenta e protege, o que dificulta seu diagnóstico e tratamento. Várias são as causas de sua ocorrência e vários sistemas orgânicos podem estar nela envolvidos, isolada ou associadamente, incluindo-se especialmente o geniturinário, o gastrointestinal, o neuropsicológico e o musculoesquelético. OBJETIVOS: Caracterizar-se clínica e demograficamente uma amostra composta de mulheres com dor pélvica crônica de origem não visceral refratária ao tratamento convencional e avaliar-se do efeito analgésico da estimulação magnética transcraniana repetitiva (EMTr) na magnitude da dor, psiquismo, função sexual e qualidade de vida. CASUÍSTICA E MÉTODOS: Dezoito doentes foram aleatorizadamente incluídas em dois grupos (A e B) de estudo para receber tratamento inicial com EMTr ativa (EMTr-a) ou EMTr sham (EMTr-s) respectivamente, aplicadas na área de representação da pelve e períneo do córtex motor primário. EMTr-a foi realizada com a frequência de 10Hz; 80% do limiar motor de repouso totalizando 3000 pulsos por sessão. A EMTr-s foi realizada com uma bobina desconectada e uma segunda bobina ativa aplicada perpendicularmente à primeira e ligada de modo a emitir sons e reverberações sobre o escalpo semelhantes ao da EMTr. Três semanas após a sessão de EMTr-a, as doentes do grupo A foram tratadas com EMTr-s e as do grupo B com EMTr-a. As avaliações foram realizadas no momento basal (D-7), e nos dias, -1, +7, + 21, +28 e +36 do início do estudo. Foram utilizados os seguintes inventários validados para a língua portuguesa: Inventário Breve de Dor; DN-4, Questionário de descritores breve de dor McGill, Inventário de Sintomas de Dor Neuropática, Escala Hospitalar de Ansiedade e Depressão, Índice da Função Sexual Feminina, WHOQOL-breve, Escala Visual Analógica e Questionário para Avaliação da Dor Pélvica e um algiometro para avaliar a sensibilidade dolorosa muscular na pelve e quadril. RESULTADOS E CONCLUSÕES: A DPC era intensa, havia escores elevados de ansiedade e depressão, a dor causou impacto negativo nas atividades físicas e diárias, na autopercepção do estado de saúde, na função sexual feminina e na qualidade de vida e houve elevada ocorrência da síndrome dolorosa miofascial nos músculos pélvicos e do quadril. A EMTr-a proporcionou melhora significativa da dor nas doentes tratadas inicialmente com EMTr-a e a EMTr-s causou melhora significativa e menos marcante da dor quando foi precedida do tratamento com a EMTr-a. Não houve modificação significativa dos valores dos escores de depressão e ansiedade e dos valores dos escores do Índice da Função Sexual Feminina nas doentes inicialmente tratadas com EMTr-a e ocorreu aumento do valor do escore ansiedade nas doentes inicialmente tratadas com EMTr-s. Houve aumento dos valores dos domínios \"psicológico\" e \"meio ambiente\" do WHOQOL-breve nas doentes tratadas inicialmente com EMTra. O resultado do tratamento inicial com EMTr-a ou EMTr-s influenciou o resultado do segundo procedimento. O limiar motor em repouso estava elevado, a inibição intracortical reduzida e a facilitação intracortical normal. Houve correlação entre o limiar motor de repouso e o maior número de descritores afetivos do Questionário de Dor McGill e entre a redução da inibição intracortical e o número aumentado de descritores afetivos do mesmo questionário. A estimulação magnética transcraniana repetitiva é procedimento seguro e alternativa terapêutica para doentes com DPC / INTRODUCTION: Non-visceral chronic pelvic pain is clinical challenge due to the diversity of structures present in the pelvis and the widespread musculoskeletal framework that surrounds, supports and protects, which makes its diagnosis and treatment very difficult and usually unsatisfactory. Many are its causes and various organs may be involved in its occurrence, either alone or in association, especially the genitourinary, gastrointestinal, musculoskeletal and neuropsychological structures. OBJECTIVES: Clinical and demographic characterization of a sample of women with non-visceral chronic pelvic pain refractory to conventional treatments and evaluation of the analgesic efficacy of repetitive transcranial magnetic stimulation (rTMS) in the magnitude of pain, psychic, sexual function and quality of life. PATIENTS AND METHODS: Eighteen patients were randomly included into two groups (A and B) accordingly the use of active rTMS (rTMS-a) or sham rTMS (rTMS-s), respectively, applied in the representation area of the pelvis and motor cortex perineum primary as the first approach. rTMS-a was performed with 10Hz, 80% of the muscle resting threshold and 3000 pulses per session. s-rTMS was performed with a disconnected coil and a second coil applied perpendicularly to the first one to generate sounds and reverberations on the scalp similar to rTMS-a. Three weeks after the session of rTMS-a the group A patients were treated with rTMS-s and the group B patients with rTMS-a. The evaluations were performed at baseline (D-7), and on days -1, +7, +21, +28 and +36 from the start of the study. The following inventories validated for the Brazilian-Portuguese language were used, Brief Pain Inventory were used; DN-4, Questionnaire brief descriptors of McGill Symptoms Inventory Neuropathic Pain, Hospital Anxiety and Depression Scale, Female Sexual Function Index, WHOQOL-brief, Visual Analogue Scale and the Questionnaire for Assessment of Pelvic Pain. A muscle algometer to assess muscle soreness in the pelvis and hip was also used. RESULTS AND CONCLUSIONS: The DPC was severe, the patients presented high scores of anxiety and depression, pain caused negative impact on physical and daily activities, self-perceived health status, female sexual function and quality of life and there was high incidence of myofascial pain syndrome the pelvic muscles and hip. rTMS-a provided significant improvement of pain in patients initially treated with rTMS-a and rTMS-s resulted in significant but less expressive improvement in pain when it was preceded by treatment with rTMS-a. There was no significant change in the values of the scores of depression and anxiety and of the Female Sexual Function Index in patients initially treated with rTMS-a it and there was an increase in the value of the score anxiety in patients initially treated with rTMS-s. There was improvement of the \"psychological\" and \"environment\" dominions of the WHOQOL-brief in patients initially treated with rTMS-a. The results of initial treatment with rTMS-a or rTMS-s influenced the outcome of the second procedure. The resting motor threshold was high, the intracortical inhibition was reduced, and the intracortical facilitation normal. There was correlation between the resting motor threshold and the affective descriptors of the McGill Pain Questionnaire and between reduced intracortical inhibition and the increased number of affective descriptors of the same questionnaire. rTMS is a safe procedure and therapeutic alternative for patients with DPC

Introdução: A osteoartrite de joelho (OAJ) é uma doença prevalente, associada a significante morbidade, caracterizada por sua cronicidade, evolução lenta e progressiva. Os principais objetivos das intervenções em pacientes com OAJ são redução da dor e melhora da capacidade funcional e dentre as intervenções os exercícios são amplamente recomendados. A literatura aponta carência de ensaios clínicos que verifique o efeito do fortalecimento dos músculos do quadril em pacientes com osteoartrite de joelho. Dessa forma, o objetivo da presente pesquisa foi analisar os efeitos da adição do fortalecimento dos músculos abdutores versus adutores do quadril a um programa de fortalecimento, terapia manual e alongamento dos membros inferiores na intensidade da dor e capacidade funcional em pacientes com osteoartrite sintomática de joelho. Métodos: Foi realizado um ensaio clínico aleatorizado, grupo paralelo, distribuição equilibrada e avaliador cego. Sessenta e seis participantes foram distribuídos aleatoriamente em dois grupos: Grupo Abdutores do Quadril (GABQ, n = 33) e Grupo Adutores do Quadril (GADQ, n = 33). Os participantes foram submetidos a um programa de tratamento fisioterapêutico por seis semanas consecutivas (12 atendimentos). Ambos os grupos realizaram aquecimento sistêmico em bicicleta ergométrica, alongamento de isquiotibiais, quadríceps femoral, tríceps sural, abdutores e adutores do quadril, terapia manual articular e miofascial para o joelho, fortalecimento de quadríceps femoral, isquiotibiais e tríceps sural. Além disso, o GABQ realizou mais três exercícios para abdutores do quadril e o GADQ realizou mais três exercícios para os adutores do quadril. Os desfechos clínicos avaliados foram: intensidade da dor avaliada pela Escala Numérica de Dor (END), capacidade funcional subjetiva pela Knee Injury and Osteoarthritis Outcome Score (KOOS) e Questionário de Lequesne, percepção da evolução clínica pela Escala de Percepção do Efeito Global e, avaliação da mobilidade funcional pelo Teste de Levantar e Caminhar Cronometrado e Teste Sentar-Levantar. Resultados: A comparação entre os grupos nos desfechos primários após seis semanas de intervenção não apresentou diferença significativa na intensidade da dor (diferença média = -1,15, IC 95% -2,44 - 0,12, TE = -0,40), domínio dor no KOOS (diferença média = 1,64, IC 95% -6,79 - 10,07, TE = 0,23) e domínio função nas atividades diárias no KOOS (diferença média = -0,12, IC 95% -8,78 - 8,54, TE = 0,05). Não houve diferença nos desfechos secundários em seis semanas e seis meses entre os grupos com pequeno tamanho do efeito. Na análise isolada de cada grupo, foi encontrada melhora significativa em todos os desfechos clínicos em seis semanas e seis meses, apenas o grupo GABQ não apresentou melhora no TGUG após intervenção. Conclusão: A adição do fortalecimento dos músculos abdutores e adutores do quadril a um programa geral de fortalecimento de membros inferiores em pacientes com osteoartrite de joelho, trouxe melhora significativa na intensidade da dor e capacidade funcional, porém, não houve diferença entre os grupos. Frente esses achados, o fisioterapeuta poderá tomar decisão clínica para fortalecimento do grupo muscular do quadril mediante sua avaliação e necessidade dos pacientes / Introduction: Knee osteoarthritis (KOA) is a prevalent disease associated with pain and functional incapacity and is characterized by chronicity and a slow, progressive evolution. The main objectives of KOA interventions are pain reduction and functional capacity improvement, and exercise is one of the most widely recommended of these interventions. The literature points to a lack of clinical trials to verify the effectiveness of hip muscle strengthening in patients with KOA. The present study aimed to compare the effects of adding hip abductor and adductor muscle exercises to a program of strengthening, manual therapy, and lower limb stretching on pain intensity and functional capacity in patients with symptomatic KOA. Methods: A randomized, parallel-group clinical trial was performed. Sixty-six participants were randomly assigned to either the hip abductor group (HABG, n = 33) or the hip adductor group (HADG, n = 33). All participants underwent standard physiotherapeutic treatment for six consecutive weeks (12 visits) that included 1) systemic warm-up on a stationary bicycle, 2) stretching of the hamstring, quadríceps femoris, sural triceps, and hip abductors and adductors, 3) manual joint and myofascial therapy for the knee, and 4) strengthening of the quadriceps femoris, hamstrings, and triceps sural. Participants in HABG performed three additional exercises for hip abductors and participants in HADG performed three additional exercises for hip adductors. A blinded evaluator collected the following clinical endpoint data: pain intensity assessed by the Numerical Pain Scale (NPS), subjective functional capacity assessed by the Knee Injury and Osteoarthritis Outcome Score (KOOS) and Lequesne\'s Algofunctional Index, perception of clinical evolution assessed by the Global Effect Perception Scale, and functional mobility evaluated by the Timed Up and Go (TUG) Test and Sit-to-Stand Test. Evaluations were performed at six weeks post baseline assessment and six month followup. Results: There were no between-group differences after six weeks of intervention for pain intensity to the NPS (mean difference = -1.15, 95% CI [-2.44, 0.12], ES = -0.40), KOOS-Pain (mean difference = 1.64, 95% CI [-6.79, 10.07], ES = 0.23) and KOOSFunction (mean difference = -0.12, 95% CI [-8.78, 8.54], ES = 0.05). There were nobetween-group differences in secondary outcomes at either six weeks post baseline assessment and six month follow-up, and effect sizes were small. In an isolated analysis of each group, a significant improvement was found for all clinical outcomes at six weeks and six months, and only HABG did not show improvement in the TUG Test after intervention. Conclusion: The addition of hip abductor and adductor muscle strengthening to a general lower limb strengthening program in patients with KOA significantly improved pain intensity and functional capacity, but there was no difference between the groups. Faced with these findings, physiotherapists should make clinical decisions to strengthen hip muscles based on individual evaluation and patient needs