Obesity is America’s fastest growing health threat. Although a primary health risk factor, obesity increases the probability of secondary health consequences such as stroke, diabetes mellitus and heart disease. Siberian hamsters offer a convenient model to study obesity, as they exhibit a photoperiod-driven reversal of obesity during the fall-winter months (i.e., short-days-SD). SD responses in the Siberian hamster, amongst others, include decreased adiposity and gonadal regression. The duration of the dark period is faithfully transmitted into a neuroendocrine melatonin (MEL) signal; that codes seasonal information. The brain communicates with body fat (white adipose tissue- WAT) via the sympathetic nervous system (SNS). The central MEL binding sites, however, necessary for the body fat/lipid mobilization responses during SDs are not precisely known, although melatonin receptor (MEL 1aR) mRNA has been co-localized with sympathetic outflow neurons of WAT in several forebrain areas. This dissertation aims to identify and to characterize the contribution of central sites that are important in seasonal responses in Siberian hamsters. Thus, I asked: Which specific brain sites are both sufficient and necessary to stimulate SD-like decreases in body, WAT and testes mass? Furthermore, I tested if SD-induced decreases in body fat mass are accompanied by increased energy expenditure, specifically brown adipose tissue (BAT) thermogenesis. It is hoped that the identification of brain sites and mechanisms involved in the effortless reversal of obesity in these animals can be applied to treatment opportunities of human obesity.

This thesis presents an adaptive tuning system that can be described as a dynamic Just Intonation tuning system, being compatible with equally tempered instruments. The tuning system is called Hermode Tuning (HMT) and the tuning used as comparison for evaluation is the standardized western tuning, the equal tempered tuning. This study investigates preferences for these two musical tuning systems, depending on whether the tunings are presented on a piano or with woodwind instruments. A listening test was done with students at the Falun Conservatory of Music, including both a vertical listening (intervalls) and a horizontal listening (cadenses and musical compositions) of Hermode tuned musical material. Overall the results showed no significant preferences for either tuning system irrespectively of what instrument it was presented with. The clearest results was that of a misjudged just intonated perfect third on the piano and a preference for an adaptively tuned piano presented in a simple harmonic structure, with a parameter setting of HMT 70%. Materials for comparison was partly taken from Hermode´s own website, but overall the attitude towards these sequenses (using a likert scale of one to five) showed a low expected value. This shows the complexity of the topic and no general conclusions regarding the choice of intonation or tuning system could be done for the presented material.

In the world today and in Turkey, poverty and its alleviation has become an important issue. As a result, detailed studies for the identification of poverty need to be done. In the recent years, the spatial aspect of the multidimensional character of poverty is gaining significance. For this purpose, in this thesis, spatial aspects of poverty are tried to be analysed using Geographic Information Systems (GIS) in the case of Ke&ccedil / i&ouml / ren District in Ankara. Firstly, a digital map of the spatial distribution of the urban poor living in Ke&ccedil / i&ouml / ren is made and linked to the database to analyse the spatial distribution. The poverty database used in this study is based on the data collected by the Social Assistance and Solidarity Foundation in the district. It includes state of poverty and some sociodemographic characteristics of the households who applied for social assistance. The analyses with respect to the methodology of this study aims at finding the common characteristics of poor settlements and the areas/households which are the poorest of the poor in Ke&ccedil / i&ouml / ren. The maps obtained as a result of spatial data analysis indicate the dense living areas of the poor, clusters of poor households, neighbourhood level poverty analysis and poor areas within neighbourhoods. There are also additional analyses which compare the characteristics of the geographical distribution of the poor with other aspects, such as land values, roads and building conditions. Such a study can be helpful to re-allocate the poverty alleviation efforts more efficiently by determining priority areas.

Tunnel structures are important investments especially for urban areas. Ke&ccedil / i&ouml / ren - Tandogan metro alignment is one of those investments executed by Ankara Metropolitan Municipality. The purpose of this research is to evaluate Tunnel Boring Machine (Earth Pressure Balance type) (TBM-EPB) performance within different lithological units encountered along Tandogan -Mecidiye segment of the Ke&ccedil / i&ouml / ren - Tandogan metro tunnel. The evaluation is based on the data obtained from traditional site investigation methods, statistical approaches and Geographic Information Systems (GIS). Complex geological and hydrogeological conditions are found to be effective in the advancement of a TBM implemented in tunnel boring works. A good understanding of the geology is essential in such cases. Available field (in-situ) and laboratory tests have been used in order to determine geological, hydrogeological and geotechnical properties of the metro tunnel alignment. Advancements in the tunnel boring process also proved that hydrogeological conditions are effective on the performance of TBM so related data are considered carefully while preparing cross-section layers and calculating weights in order to display the distribution of excavation difficulty classes through the tunnel alignment.

Reasons like increases in the price and demand of energy in the last years, growing interest and support in the renewable energy resources, development of social environmental consciousness, interest in using domestic resources, having legal regulations has promoted the interest in the electricity production from geothermal energy. For the effective and productive use of existing resources, important data of geothermal regions are obtained with well tests. Well tests are the studies which starts while the well is drilling, continues after the well completion during the process of operation planning with optimum performance suitable to geothermal source and presents continuation also in the operation stage as required for the dynamic structure of geothermal systems. In Aydin Kuyucak Pamuk&ouml / ren region three wells are drilled, achieved results are positive. At AP1 well only CO2 emission is present, no test is done for this well. With the tests for AP2 and AP3 wells temperature, pressure and production values are determined. By the results of these tests, it is determined that this region will be one of the important fields in the West Anatolian Region with current temperature and production rate. In this study, the geothermal energy recoverable from this region is calculated with volume method of geothermal resource assessment. Monte Carlo simulation technique is used with an add-in software program @RISK to Microsoft EXCEL. Electrical power capacity of Aydin-Pamuk&ouml / ren geothermal field is determined as 45.2 MW with 90 % probability. The most likely electrical power value was found to be 78.75 MW with a probability of 69 %. The number of wells required are 10 for a production capacity of 200 t/hr and 7 for a production capacity of 300 t/hr at each well head.

No description available.

Bakgrund: I Sverige lever cirka 5000 personer med spinalskada. Där spinalskadan lett till nedsatt blåsfunktion är ren intermittent kateterisering (RIK) den metod som rekommenderas i första hand. Syfte: Att undersöka hur personer med traumatisk spinalskada som använder ren intermittent kateterisering (RIK) upplever detta. Syftet var även att ta reda på vilka hanteringsstrategier som finns för att underlätta det dagliga livet. Metod: En kvalitativ metod med semistrukturerade intervjuer användes där fem personer med traumatisk spinalskada som använder RIK intervjuades. Resultat: Att behöva tillägna sig metoden väckte blandade känslor. Män upplevde det lättare att RIKa jämfört med kvinnor. Den egna kompetensen och kunnandet om metoden RIK ökade med tiden och de hittade nya hanteringsstrategier för att underlätta vardagen. Informanterna var medvetna om vikten av god hygien för att undvika urinvägsinfektioner. Däremot framgick det inte om informanterna var medvetna om kopplingen mellan vikten av regelbunden RIKning, residualurin i blåsan och uppkomsten av urinvägsinfektioner. Slutsats: Personer som använder RIK upplever det som nödvändigt och avgörande för att kunna leva ett normalt liv. Hanteringsstrategier är planering och anpassande av metoden efter fysisk förmåga och den egna vardagen. Behovet av stöd hos personer med spinalskada som använder RIK är individuellt och varierar. Adekvat stöd och utbildning underlättar och hjälper personer med nedsatt blåsfunktion som använder RIK att ta kontroll över utövandet och främjar följsamheten och långsiktig hälsa avseende urinvägarna. / Background: About 5,000 people in Sweden live with a spinal injury. Where the spinal injury leads to impaired bladder function, clean intermittent catheterization (CIC) is the method recommended in the first place. Aim: To examine  how individuals  with traumatic  spinal injury  using clean  intermittent catheterization experience the method. The aim was also to find out coping strategies available to facilitate daily life. Methods: A qualitative approach with semi-structured interviews was used where five people with traumatic spinal injury were interviewed. Results: The need to use CIC brought about mixed feelings among informants. Men felt that it was easier for them to use clean intermittent catheterization compared to women. Their expertise and knowledge increased with time and they found new coping strategies to facilitate everyday life. The informants were aware of the importance of good hygiene to prevent urinary tract infections. However, it was not clear if the informants were aware of the connection between the importance of using clean intermittent catheterization regularly, residual urine in the bladder and the occurrence of  urinary  tract  infections. Conclusion: People who use CIC experience it as essential and vital in order to live a normal life. The need for support of people with spinal injury who use CIC is individual and varies. Adequate support and training for people with impaired bladder function using CIC facilitates and helps them to take control initially and promotes an ongoing adherence and long-term health regarding urinary tract.

I denna uppsats behandlas kommersiella säljares skadeståndsansvar när levererade produkter är behäftade med funktionsfel. Funktionsfel i produkter kännetecknas av att felaktiga detaljer från tillverkningen av en beståndsdel orsakar en minskad funktion i slutprodukten. I uppsatsen klarläggs även vilken betydelse ansvarsförsäkringen har för köparens möjligheter att erhålla ersättning när denna drabbats av funktionsskador härledda av köpt felaktig egendom. I uppsatsen undersöks ingrediens- och komponentskador ur främst ett skadestånds- och försäkringsrättsligt perspektiv, med avsikten att klargöra säljarens skadeståndsskyldighet i inomobligatoriska förhållanden samt vilka ansvarsgrunder som är aktuella i utomobligatoriska relationer. Även det försäkringsrättsliga skyddet för ingrediens- och komponentskador utreds, samt betydelsen för försäkringsskyddet huruvida den inträffade skadan är en skadeståndsrättslig sakskada eller en skada som ryms inom säljarens köprättsliga felansvar undersöks. Uppsatsen innehåller därutöver ett empiriskt avsnitt, vars avsikt är att klarlägga hur de svenska ledande försäkringsbolagens relevanta försäkringsvillkor är utformade samt vilken syn försäkringsbolagen har på begreppet sakskada och funktionsskadeprincipen.

Made available in DSpace on 2014-12-17T15:07:07Z (GMT). No. of bitstreams: 1 MariaEQ_TESE.pdf: 2173961 bytes, checksum: a391cf6fb0c1d9be4bd9273ea9a987d1 (MD5) Previous issue date: 2013-08-28 / O objetivo deste trabalho ? investigar como as representa??es discursivas do locutor e dos alocut?rios s?o constru?das no discurso de ren?ncia ao mandato de senador, proferido por Antonio Carlos Magalh?es (ACM), na 62? sess?o deliberativa ordin?ria, em 30/5/2001. A perspectiva te?rica que adotamos situa-se no campo da Lingu?stica do Texto, com foco na abordagem da An?lise Textual dos Discursos ATD (Adam, 2011). A no??o de representa??o discursiva apresentada pela ATD constitui um dos aspectos da dimens?o sem?ntica do texto e baseia-se parcialmente nos trabalhos de Grize sobre a esquematiza??o (1990, 1996). Complementamos as categorias de an?lise com contribui??es que nos permitem detalhar a express?o lingu?stica, textual, e discursiva das representa??es discursivas (Neves, 2006; Castilho 2010; Rodrigues, Passeggi, Silva Neto, 2010; Rodrigues et al. 2012; Passeggi, 2012). O enfoque metodol?gico ? qualitativo, descritivo e interpretativista (Minayo, 1994; Trivin?s; 1987; Gil, 2002). Os procedimentos de an?lise utilizam as categorias sem?nticas de referencia??o, predica??o, modifica??o (de referentes e predica??es), localiza??o espacial e temporal, conex?o e compara??o. A representa??o discursiva do locutor (ACM) ? constitu?da pelo conjunto de representa??es mais espec?ficas, expressas nas referencia??es e nas suas modifica??es: v?tima; pol?tico; sigla; baiano, nordestino; presidente do senado; senador confiante; condenado. ACM, como protagonista, assume sempre a sua voz no discurso, manifesta seus pontos de vista e posiciona-se como sujeito ativo, consciente da import?ncia do seu papel pol?tico e social, que o torna alvo e v?tima das a??es dos advers?rios. Complementando essa referencia??o, as predica??es e suas modifica??es se expressam atrav?s de verbos de a??o, em especial, verbos na 1? pessoa do singular que marcam o tempo presente, real e conclusivo de a??es que constroem um cen?rio positivo para si mesmo. A localiza??o temporal e espacial, indica as a??es realizadas pelos participantes nas diversas etapas temporais selecionadas pelo texto, articuladas a tr?s espa?os principais: o Senado Federal, o Brasil e, naturalmente, a Bahia. Por sua vez, conectores adversativos (sobretudo, mas ), explicativos e condicionais acompanham e estruturam o ritmo argumentativo do discurso de ren?ncia de ACM

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-06-02T22:48:59Z No. of bitstreams: 1 SamaraTaianaDeLimaSilva_DISSERT.pdf: 1111693 bytes, checksum: 6b3a12c02bdae413ea1dbf5562bf11c8 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-06-09T21:13:50Z (GMT) No. of bitstreams: 1 SamaraTaianaDeLimaSilva_DISSERT.pdf: 1111693 bytes, checksum: 6b3a12c02bdae413ea1dbf5562bf11c8 (MD5) / Made available in DSpace on 2017-06-09T21:13:50Z (GMT). No. of bitstreams: 1 SamaraTaianaDeLimaSilva_DISSERT.pdf: 1111693 bytes, checksum: 6b3a12c02bdae413ea1dbf5562bf11c8 (MD5) Previous issue date: 2017-01-27 / A presente pesquisa teve por objeto a recep??o da pol?tica de ren?ncia fiscal no estado do Rio Grande do Norte e no munic?pio de Natal. Criado em 1986, por meio da Lei Sarney (n? 7.505/86), o modelo descrito foi desenvolvido como uma forma que o Estado encontrou para retirar de si a responsabilidade pelo investimento do setor em comento, uma vez que ? transferida para a iniciativa privada a decis?o pelo financiamento cultural, por meio de descontos tribut?rios a ela concedidos. Extinta a Lei Sarney, entrou em vigor a Lei Rouanet (n? 8.313/1991), atuante at? os dias presentes, e que serviu como espelho para que os estados e munic?pios criassem suas legisla??es culturais locais. No ?mbito do estado do Rio Grande do Norte, temos a Lei C?mara Cascudo (n? 7.799/1999) e, em sua capital, Natal, a lei Djalma Maranh?o (n? 4.838/1997)ambas atuando como principais respons?veis pelo financiamento cultural local. Nesta perspectiva, o presente trabalho objetivou uma reflex?o sobre a recep??o da referida pol?tica em face da produ??o cultural da cidade de Natal - RN. Foi realizada uma pesquisa emp?rica na qual foram entrevistados gestores, produtores e grupos culturais que atuam no ?mbito local, sobretudo, uma reflex?o acerca da sufici?ncia ou n?o deste modelo de financiamento para o provento da cadeia produtiva cultural local. Por fim, a pesquisa concluiu a insufici?ncia da pol?tica analisada em face da realidade da produ??o cultural local, raz?o que se justifica pela falta de interesse da classe empresarial para com a causa do patroc?nio cultural e, sobretudo, pela aus?ncia de campanhas de sensibiliza??o e est?mulos para que esta classe abrisse mais as suas possibilidades para o apoio cultural, pauta que deveria ser gerida pelos ?rg?os de fiscaliza??o e fomento do setor da cultura local. / The present research had as by object the reception of the fiscal renunciation policy in the state of Rio Grande do Norte and in the municipality of Natal. Created in 1986, through the Sarney Law (n? 7,505 / 86), the model described was developed as a way that the State found to remove from itself the responsibility for the industry's investment in comment, since it is transferred to the private ents the decisions about the cultural financing, by means of tax deductions granted to it. After the Sarney Law came into force, the Rouanet Law (n? 8,313 / 1991), which has operated up to the present day, came into force and served as a mirror for states and municipalities to create their local cultural legislations. In the state of Rio Grande do Norte, have the C?mara Cascudo Law (n? 7999/1999) and, in its capital, Natal, the Djalma Maranh?o Law (n? 4,838 / 1997), both acting as the main responsible for local cultural financing . In this perspective, the present research aimed to reflect on the reception of said policy in the cultural production of the city of Natal - RN. An empirical research was carried out in which managers, producers and cultural groups were interviewed at the local level, mainly a reflection about the sufficiency or not of this financing model for the local cultural productive chain. Finally, the research concluded the insufficiency of the politics analyzed in the face of the reality of the local cultural production, reason that is justified by the lack of interest of the business class towards the cause of the cultural patronage and, mainly, by the absence of campaigns of sensitization and stimuli so that this class opened up more possibilities for cultural support, which should be managed by the organs of supervision and promotion of the local culture sector.