It is a fact that software has bugs. These bugs can lead to failures. Especially dependability and security failures are a great threat to software users. This thesis introduces four novel approaches that can be used to automatically harden software at the user's site. Automatic hardening removes bugs from already deployed software. All four approaches are automated, i.e., they require little support from the end-user. However, some support from the software developer is needed for two of these approaches. The presented approaches can be grouped into error toleration and bug removal. The two error toleration approaches are focused primarily on fast detection of security errors. When an error is detected it can be tolerated with well-known existing approaches. The other two approaches are bug removal approaches. They remove dependability bugs from already deployed software. We tested all approaches with existing benchmarks and applications, like the Apache web-server.

Perspektiven im Netzbereich C.A.N. - Chemnitzer AbsolventenNetz Grafische Benutzeroberfl¨achen im Netz (VNC) PGP 5.x und GNUPG Neuigkeiten bei der Secure Shell (SSH) Vim 5.x Richtlinien zur Sicherheit im Campusnetz Ein Jahr Einsatz von Windows NT im URZ

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Vortragsfolge: J. Anders Ein H261-Player in Java D. Thie Wavelet- und fraktale Kompression von Videodaten A. Karwath Audiokomprimierung J. Hüttmann Chemnitzer Absolventennetz M. Ehrig Betrachtungen zu verteilten Filesystemen Th. Müller Migration und Datensicherung im MR-AFS M. Clauß Management von Nutzeranforderungen im URZ M. Tautenhahn Systemmanagement auf der Basis von LDAP und SSL S. Brose Zero-Administration-Client mit Ignite-UX und CFENGINE Chr. Ziegler Backupdienst - Stand und Perspektiven Th. Müller BOF: Sicherheit im Campusnetz A. Breiler Server Side Applets N. Schulze Java Beans C. Ranfeld Softwaremanagement RPM vs. OSD G. Heide Neue PD-Software für graphische Benutzeroberflächen J. Wagner Untersuchung zur Neugestaltung der WWW-Seiten zur Softwareausleihe B. Auerbach Digitale Signaturen in MONARCH W. Riedel Lyx - das Wysisyg-LaTeX? W. Riedel BOF: StarOffice - Die vertane Chance? G. Fischer Skalierbarkeit von Serverleistung und Level-4-Switching H. Trapp aktuelle Entwicklungen bei: PGP 5.0, TLS, SSH, Kerberos, vim-5.0 R. Sontag Kommunikationsserver in Schulen: Stand der Vernetzung U. Hübner Perspektiven im Netzbereich

Background: Antidepressants are widely used in the treatment of chronic pain. Applied doses are lower than those needed to unfold an antidepressive effect. While efficacy of antidepressants for chronic pain has been reported in large randomized-controlled trials (RCT), there is inconsistent data on adverse effects and tolerability. We aimed at synthesizing data from RCT to explore adverse effect profiles and tolerability of antidepressants for treatment of chronic pain. Methods: Systematic literature research and meta-analyses were performed regarding side effects and safety of different antidepressants in the treatment of chronic pain according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The National Center for Biotechnology Information library and MEDLINE were searched. Randomized placebo-controlled trials were included in quantitative data synthesis. results: Out of 1,975 screened articles, 33 papers published between 1995 and 2015 were included in our review and 23 studies were included in the meta-analyses. A higher risk for adverse effects compared to placebo was observed in all antidepressants included in our analyses, except nortriptyline. The most prevalent adverse effects were dry mouth, dizziness, nausea, headache, and constipation. Amitriptyline, mirtazapine, desipramine, venlafaxine, fluoxetine, and nortriptyline showed the highest placebo effect-adjusted risk of adverse effects. Risk for withdrawal due to adverse effects was highest in desipramine (risk ratio: 4.09, 95%-confidence interval [1.31; 12.82]) followed by milnacipran, venlafaxine, and duloxetine. The most common adverse effects under treatment with antidepressants were dry mouth, dizziness, nausea, headache, and constipation followed by palpitations, sweating, and drowsiness. However, overall tolerability was high. Each antidepressant showed distinct risk profiles of adverse effects. conclusion: Our synthesized data analysis confirmed overall tolerability of low-dose antidepressants for the treatment of chronic pain and revealed drug specific risk profiles. This encompassing characterization of adverse effect profiles might be useful in defining multimodal treatment regimens for chronic pain which also consider patients’ comorbidities and co-medication.

Background: Antidepressants are widely used in the treatment of chronic pain. Applied doses are lower than those needed to unfold an antidepressive effect. While efficacy of antidepressants for chronic pain has been reported in large randomized-controlled trials (RCT), there is inconsistent data on adverse effects and tolerability. We aimed at synthesizing data from RCT to explore adverse effect profiles and tolerability of antidepressants for treatment of chronic pain. Methods: Systematic literature research and meta-analyses were performed regarding side effects and safety of different antidepressants in the treatment of chronic pain according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The National Center for Biotechnology Information library and MEDLINE were searched. Randomized placebo-controlled trials were included in quantitative data synthesis. results: Out of 1,975 screened articles, 33 papers published between 1995 and 2015 were included in our review and 23 studies were included in the meta-analyses. A higher risk for adverse effects compared to placebo was observed in all antidepressants included in our analyses, except nortriptyline. The most prevalent adverse effects were dry mouth, dizziness, nausea, headache, and constipation. Amitriptyline, mirtazapine, desipramine, venlafaxine, fluoxetine, and nortriptyline showed the highest placebo effect-adjusted risk of adverse effects. Risk for withdrawal due to adverse effects was highest in desipramine (risk ratio: 4.09, 95%-confidence interval [1.31; 12.82]) followed by milnacipran, venlafaxine, and duloxetine. The most common adverse effects under treatment with antidepressants were dry mouth, dizziness, nausea, headache, and constipation followed by palpitations, sweating, and drowsiness. However, overall tolerability was high. Each antidepressant showed distinct risk profiles of adverse effects. conclusion: Our synthesized data analysis confirmed overall tolerability of low-dose antidepressants for the treatment of chronic pain and revealed drug specific risk profiles. This encompassing characterization of adverse effect profiles might be useful in defining multimodal treatment regimens for chronic pain which also consider patients’ comorbidities and co-medication.

Unter all den denkbaren Effekten von Sozialpolitik auf Politik untersuche ich hier die Möglichkeit, dass Sozialpolitik den Handlungsspielraum von Politik absichert; dass Sozialpolitik Erfolgsvoraussetzung von Politik ist. Es geht also um die Frage, in welcher Weise staatliche Sozialpolitik eine Voraussetzung für Politik ist, um die Frage der sozialpolitischen Selbstermöglichung von Politik. Solch ein Zugang muß den gewohnten Blick auf Staat und Sozialpolitik irritieren. Denn üblicherweise werden sozialpolitische Verpflichtungen des Staates als Beeinträchtigung, als Überforderung staatlicher Handlungsfähigkeit gesehen. Zuerst werde ich kurz auf die Entwicklung des sozialwissenschaftlichen Verständnisses der gesellschaftlichen Bedingtheit staatlicher Politik eingehen. Dann werde ich ein grundsätzliches Dilemma staatlicher Steuerung darstellen. Anschließend werde ich dieses anhand der aktuellen Schwierigkeiten mehrerer politischer Großprojekte veranschaulichen. Dann werde ich nach einem Theoriemuster zur Interpretation dieser Schwierigkeiten suchen, mit dem sich zeigen läßt, wie Sozialpolitik einpassbar ist. Und schließlich werde ich Konsequenzen diskutieren, die sich aus der Integration von Sozialpolitik in eine soziologische Theorie der Gesellschaft ergeben.:Einleitung; Unsicherheit, Sozialpolitik und Demokratie; Staat und Politik; Zeithorizonte von Politik und Interessen; Sozialpolitisch gestützte Politik; Funktionale Differenzierung und Sozialpolitik

Intranet - Erwartungen und Entwicklungen JavaOS - ein Betriebssystem fuer Intranets Network Computer - Eine Verkaufsstrategie? Was gibt es schon? Netscape IFC's - Gestalten von graphische Nutzerinterfaces WWW-Sicherheitsaspekte - ein heisses Thema: Sicherheit im Netz Aufbau einer Certification Authority - z.B. IN e.V. Chemnitz Authentisierung und Verteilung von Konfigurationsfiles - am Bsp. URZ