Global ETD Search

101	Genetic variation in humans and chimpanzees in the prion protein gene Soldevila Trepat, Marta 20 June 2005 (has links) En el gen de la proteïna priònica, o PRNP, hem observat que el particular patró de variació que hem trobat basant-nos en dades de seqüenciació en humans es deu a selecció positiva, i que el mètode utilitzat per detectar selecció és crític. Utilitzant dades basades en SNPs es pot introduir un biaix al aplicar tests de neutralitat basats en diversitat de seqüències, i això pot portar a conclusions errònies. A més, hem vist que els polimorfismes en els codons 129 i 219 presenten gran diferències de freqüència en diferents poblacions humanes i també hem vist que aquestes posicions estan fixades en ximpanzés. La variació trobada en controls ha estat comparada amb el patró de variació existent en pacients per la mateixa regió. La reseqüenciació del gen PRNP en un gran nombre de mostres humanes i de ximpanzés ens ha permès obtenir un gran nombre d´informació d´aquest gen. / In the prion gene or PRNP, we have observed that the particular pattern of variation that we have found in this gene based on sequencing data in humans is due to positive selection, and that the method and the approach used to detect this selection critical. Ascertainment bias can be introduced by using SNP data and applying neutrality tests based on sequence diversity, therefore leading to anomalous conclusions being drawn. Moreover, we have seen that polymorphisms in codon 129 and 219 have big differences in frequency in different human populations and we have also seen that these positions are fixed in chimpanzees. The normal variation that we found in controls have been then compared with patients for the same region. The resequencing of PRNP in a very large sample of humans and chimpanzees has provided a great deal of information on this gene. primats ximpanzé Creutzfeldt-Jakob Insomni Fatal familiar BSE malalties priòniques selecció balancejadora selecció positiva selecció seqüència haplotip canibalisme CJD 129 prió PRNP primates chimpanzee Fatal familial insomnia Creutzfeldt-Jakob prion diseases BSE balancing selection positive selection selection sequence haplotypes cannibalism CJD 129 PRNP prion 57 575
102	Sangvinolent berättande : En studie av Yu Huas roman En handelsman i blod / Sangvinolent Narration : A Study of Yu Hua's Novel Chronicle of a Blood Merchant Engdahl, Lin January 2011 (has links) The present MA thesis analyzes how body and blood functions as historical and narrative elements in Yu Hua's novel Chronicle of a Blood Merchant (1995). In the novel, the story and the plot can not be regarded as disparate items; the two levels of the text are tightly interwoven by what the thesis introduces as a sangvinolent narration. The term conceptualizes the use of blood as a structural element and the thrust of the text, in this case how the ability to sell blood is a prerequisite for the story and the plot. Close readings reveal the structural correlations between the blood-selling main-character Xu Sanguan in the plot on the one hand, and in the story on the other, which can be detected to have, inter alia, an effect on the temporality of the narrative. Themes linked to identity, belonging and survival (performativity, mimicry, reification and alienation) permeate the text. In the novel the body and bodily fluids are sacrificed in order to form and enforce perceptions of identity and societal roles. The rhetorical use of ‘blood and tears’ (Ch. xue yu lei) indicates thematic connections to the Chinese revolutionary literature, and furthermore, the use of flesh and blood can be read in relation to the cannibalistic discourses crucial to Chinese modernity since Lu Xun. alienation avant-garde blood blood-selling cannibalism China Chronicle of a Blood Merchant corporality mimicry narratology performativity reification Yu Hua 许三观卖血记，余华 alienation avantgarde blod blodsäljande En handelsman i blod kannibalism Kina kroppslighet mimicry narratologi performativitet reifikation Yu Hua Literature Litteraturvetenskap
103	Äcklet, Äcklet : En äckelstudie om doft, kroppsvätskor och skriftliga spyor samt att äta sig själv och andra i Aliide, Aliide, Parfymen, Nekrofilen, Våtmarker och Tid för kärlek / Disgust, Disgust : A disgusting study about scent, bodyfluids, writing vomit and eating oneself and others in Aliide, Aliide, Parfymen, Nekrofilen, Våtmarker and Tid för kärlek Guldbacke Lund, Linnéa January 2021 (has links) This essay explores and examines disgust in five literary figures and books based on scent, bodyfluids and abjection. Together with Julia Kristeva's Powers of Horror: An Essay on Abjection and Sara Ahmed's "The Performativity of Disgust" in The Cultural Politics of Emotion, I analyze these books, and my position as a researchsubject. The questions I ask are: What does disgust mean? How do the subject's boundaries shift when things penetrate the body? How are scents, body fluids and disgust expressed in relation to power and the female body? And what does it mean that I stick my reading experiences on the texts I read? The analysis begins in Mare Kandre's novel Aliide, Aliide and how gaze, power and girlhood are made, as well as how abjection takes place in the intake of milk and larvae. Body in body and body against body are analyzed based on Aliide's disgust in the novel. I discuss how something growing inside is experienced as disgusting and frightening and connect it to the pregnant body and the fetus as abjection. In the second chapter of the analyze, it is Parfymen: berättelsen om en mördare by Patrick Süskind that focuses on the scent of the female body that Grenouille, the main character tries to extract and master. The gaze on the female body and the extraction of fragrance is in focus here and in Nekrofilen by Gabrielle Wittkop, Lucien's desire for the dead body is examined. The body fluids, such as the vomit that the bodies excrete can be read as limits to life and death. In the third and final analysis section, I read these books with affect. I reconnect to my introduction where Ulf Lundell's poems made me feel disgusted. I use Ahmed's concept of performativity to discuss how cannibalism - reading - eating body fluids are connected, and how writing about disgust, is a form om vomiting. I examine my own writing subject and what an affective reading does to literary studies and the research position. In conclusion, I discuss how the universal and the subjective making of disgust effect research. Disgust Abjection Scent Bodyfluids Cannibalism Vomit Research position Reading Writing Subject borders female body gaze power power relations Ahmed Kristeva repulsive effects affective performativity äckel abjekt doft lukt kroppsvätskor spy kräkas kannibalism forskarsubjekt gränser läsandesubjekt skrivandesubjekt affektiv performativitet makt kvinnokropp död motstånd effekt General Literature Studies Litteraturvetenskap
104	SOUS LE SPECTRE DU PÈRE: POÉTIQUE ET POLITIQUE DE LA DÉPENDANCE ET DU SEVRAGE DANS LE ROMAN POSTCOLONIAL AFRICAIN SHAMBA, MBUMBURWANZE N 27 June 2011 (has links) This thesis analyzes the major theme of ‘postcolonial genealogy’ in portraying the African bending under the weight of colonial history in Le vieux nègre et la médaille, Une vie de boy of Ferdinand Oyono and Le Chercheur d’Afriques of Henri Lopes. Being a product of a colonial Genesis, the African character runs behind the colonizer’s mirror through his Civilizing Mission. René Girard’s ‘double bind’ theory explains how this cultural assimilation is, in Le vieux nègre et la médaille and Une vie de boy, a dead end because the colonizer needs a subordinate and not an equal. The cohabitation of a black housewife with the French Commander in Le Chercheur d’Afriques should be seen as simply an allegory of postcolonial Africa’s dependency on the West. The consequences of the feminization of the African continent are enormous in the post-colonial imaginary. While the colonizer had conquered Africa with his Herculean body, in Oyono’s novels, his Fall is obtained through the aesthetics of Bakhtinian ‘rabaissement’ which degrades his ‘grotesque body’ to that of the colonized. The colonizer and the colonized are neutralized and leveled in their perishable bodies, thus, making futile the Civilizing Mission that operated by ranking races. Power is never total. It is always imperfect, and can never destroy a subjectivity that resists it. In Oyono’s novels, the Fall of the colonial Father is also obtained through the inquisitive gaze that the colonized return back to the colonizer, and through their ‘subversive mimicry’ that parodies his codes. In Une vie de boy and Le Chercheur d’Afriques, the ‘son-Father’ relationship between the hero and the colonial Father, is also symbolic of the ‘Africa-West’ rapports. Living under the specter of the Father, the son has to negotiate his survival between weaning and parricide. The biological miscegenation in Le Chercheur d’Afriques is a metaphor of the ‘rhizome identity’ of the postcolonial African who renounces both the Fathers of Negritude and those of the Civilizing Mission. / Thesis (Ph.D, French) -- Queen's University, 2011-06-24 12:43:30.006

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