Tidigare forskning pekar på att det kan finnas samband mellan vissa psykologiska faktorer och utveckling av depression och ångest. Därför var syftet med denna studie att undersöka huruvida olika psykologiska faktorer påverkar risken att utveckla depression samt ångest vid en uppföljning efter tre år. Studien baserades på data som insamlats vid det första (T1) och det andra (T2) mättillfället i den longitudinella populationsbaserade Miljöhälsostudien i Västerbotten. Samplen i denna undersökning bestod av deltagare som inte hade ångest (n=1930), och deltagare som inte hade depression (n=2120) vid T1. I studien undersöktes i vilken utsträckning upplevelse av utmattning, insomni, känsla av hjälp- och hopplöshet, stress, självskattad ohälsa, ångest och depression vid T1 ökade risken för depression respektive ångest vid T2. Logistiska regressionsanalyser visade på en signifikant ökad risk för att utveckla depression vid T2 (Oddskvot; OK=1.99-3.64) för samtliga riskfaktorer. Riskfaktorerna depression, utmattning, hjälp- och hopplöshet och självskattad ohälsa ökade risken för att utveckla ångest vid T2 signifikant (OK=2.37-3.78). Sammanfattningsvis visar resultaten att riskfaktorerna indikerar en i varierande grad ökad risk för att utveckla depression och ångest. Kännedom om riskfaktorer kan vara ett betydelsefullt stöd för att i ett tidigt skede sätta in interventioner och därmed förhindra senare insjuknande i depression och ångest. / Previous research suggests that there may be a link between certain psychological factors and development of depression and anxiety. The purpose of this study was therefore to investigate how different psychological factors affect the risk of developing depression and anxiety in a follow-up three years later. The study was based on data from baseline (T1) and follow-up (T2) in the Västerbotten Environmental Health Study, a longitudinal population- based study. The sample consisted of participants who did not have anxiety (n = 1930), and participants who did not have depression (n = 2120) at T1. The study examined the extent to which experience of exhaustion, insomnia, feelings of helplessness and hopelessness, stress, low self-rated health, anxiety and depression at T1 increased the risk of depression and anxiety at T2, respectively. Logistic regression analyses showed a significantly increased risk of developing depression at T2 (Odds ratio; OR = 1.99-3.64) for all risk factors. The risk factors depression, exhaustion, feelings of helplessness and hopelessness and low self-rated health significantly increased the risk of developing anxiety at T2 (OR = 2.37-3.78). In conclusion, the results show that the risk factors indicate a varying degree of increased risk of developing depression and anxiety. Knowledge of risk factors is important as support for initiating interventions at an early stage and thus preventing later onset of depression and anxiety.

Syftet med studien var att undersöka vilka känslor klimataktivister upplever idag inför framtiden samt vilka känslor de förväntas uppleva i framtiden. Urvalet bestod av nio klimataktivister bosatta i Sverige som engagerar sig inom klimatfrågor genom en eller flera ideella organisationer. Datan samlades in genom story-completion task och semistrukturerade intervjuer och analyserades med induktiv tematisk analys. I resultatet av studien framkom att deltagarna upplever negativt laddade känslor som rädsla, hopplöshet och skuld – samt positivt laddade känslor, som hoppfullhet, inför framtiden idag. Samma resultat syntes i de känslor som förväntas upplevas i framtiden. Anledningen till de negativt upplevda känslorna är delvis deras känslor av misstro gentemot dagens samhällssystem, dagens politik och människors ovilja till beteendeförändring. Flera av deltagarna uppgav att de vill tro på att det är möjligt att skapa en framtid som stämmer överens med deras förhoppningar för att finna motivation och fortsätta orka engagera sig för klimatet; en form av känsloreglering. / The purpose of this study was to investigate which emotions climate activists experience today regarding the future and which emotions they expect to experience in the future. The sample consisted of nine climate activists living in Sweden that are engaged in climate issues through one or more non-profit organizations. The data was collected through story-completion task and semi structured interviews and was analyzed with inductive thematic analysis. The results show that the participants experience negatively charged emotions such as fear, hopelessness and guilt – and positively charged emotions, such as hopefulness, regarding the future today. The same results were seen in the emotions who are expected to be experienced in the future. The reason for the negatively charged emotions seems to be their experience of a distrust of today’s social system, today’s politics and people’s disinclination to change their behavior. Most of the participants stated that they want to believe that it’s possible to create a future that matches their hope in order to find motivation and the energy to keep being active for the climate; a form of emotion regulation.

Student Number : 7820500 - MA research report - School of Psychology - Faculty of Humanities / Internationally, suicide is highly prevalent among adolescents and young adults, and South African data suggest that suicide is a serious problem that is increasingly affecting the Black population and young men in particular. This study aimed firstly to investigate the prevalence of suicidal behaviour among young adults, and, in a sample of 85 young people (aged 19-30), one in seven had previously attempted suicide, and almost one in three had recently thought about killing themselves. Sociological research has shown that religion has a predominantly protective effect with regard to suicide, however psychological research, while providing evidence for a similar relationship, has also shown that religious strain may contribute to suicidality. This study sought to establish whether a relationship exists between suicidal ideation (and positive ideation), and various indicators of religiosity. Unexpectedly, given the research trends, suicidal ideation was significantly positively associated with self-reported religious salience (r = .297, p = .006), and with the collaborative/deferring religious coping style (r = .301, p = .005), characterized by higher levels of religiosity. Suicidal ideation was significantly negatively associated with the self-directing style (r = -.331, p = .002), favoured by less religious participants. Positive ideation was unrelated to religious salience, participation, and both religious coping approaches. Various explanations were proposed for these results. Cognition is a central pathway for suicidality, and insecure religious attachment, when triggered by stressors, may set in motion a cognitive process involving negative religious attributions and harmful religious coping strategies – typical symptoms of religious strain which has been associated with suicidal behaviour. Maladaptive religious beliefs and behaviours may also have a negative impact on depression, hopelessness and helplessness, all vulnerability factors for suicidal behaviour in young people. It is also possible that, when faced by life challenges that exceed coping capacity, individuals may be more likely to turn to God, while simultaneously experiencing hopelessness, depression and suicidal ideation. Finally, the gender skew in the sample may have resulted in the high levels of suicidal behaviour and religiosity, and the positive relationship between them. Vulnerability to suicidal behaviour in young adults is a multifaceted problem, and religion, itself a multidimensional concept, is one of many factors that may provide protection against or contribute to suicidal behaviour. In order to understand the complex problem of vulnerability to suicidal behaviour in young adults, there is a need for further multivariate research.

Introdução: A infecção crônica pelo vírus da hepatite C (HCV) é considerada uma doença sistêmica com numerosas manifestações extra-hepáticas. Comprometimento do sistema nervoso periférico e alterações neuropsiquiátricas são relatadas em algumas séries, com certa heterogeneidade entre elas. Embora alterações cognitivas tenham sido descritas, alguns estudos não comprovaram esta associação. Poucos estudos sobre o tema foram realizados no Brasil. Objetivo: estudar alterações do sistema nervoso periférico e alterações neuropsiquiátricas nos pacientes com infecção pelo HCV e verificar se têm relação com genótipo viral, grau de fibrose hepática e presença de autoanticorpos. Método: 76 pacientes adultos (40 mulheres) com 18 anos ou mais de idade portadores de infecção crônica por HCV, virgens de tratamento, sem sinais de encefalopatia hepática franca, não portadores do vírus da Hepatite B (HBV), vírus da imunodeficiência adquirida (HIV) ou sífilis foram avaliados no período de agosto de 2009 a fevereiro de 2016 e comparados com grupo controle composto por 76 indivíduos não portadores de HCV, HBV, HIV ou sífilis (43 mulheres) com distribuição semelhante quanto ao gênero, faixas etárias e graus de escolaridade. Pacientes e controles foram submetidos a avaliação clínica, avaliação cognitiva breve [Miniexame do Estado Mental (MEEM), teste do desenho do relógio (TDR), teste de fluência verbal (FV) semântica, teste dos dígitos em ordem direta e indireta (WAIS-III)] e avaliação do humor, ansiedade e desesperança (Inventário de Beck). Os pacientes com hepatite C foram submetidos a extensa bateria de exames laboratoriais, determinação do genótipo, dosagem de insulina, gamaglobulinas, crioglobulinas (CGs), fator reumatoide (FR), frações do complemento e pesquisa de autoanticorpos. Resultados de biópsias hepáticas realizadas em menos de 18 meses da avaliação inicial no estudo foram considerados para análise. Além de exames para inclusão no estudo, os controles foram submetidos a avaliação laboratorial. O programa SPSS 20 (Statistical Package for the Social Sciences) foi utilizado para análise estatística. Resultados: Neuropatias periféricas (NP) foram encontradas em 29 pacientes (38,1%) e 14 controles (18,3%) [p=0,007]. Dos pacientes portadores de HCV com NP, 12 (41,4%) apresentavam mononeuropatias (MN) ou mononeuropatias múltiplas (MNM), 7 (24,1%) polineuropatias (PNP) sensitivas ou sensitivomotoras, 5 (17,2%) PNP com MN ou MNM sobrepostas, 4 (13,8%) radiculopatias e 1 (3,4%) neuropatia motora pura (1/29). Dos 14 portadores de NP no grupo controle, 8 (57,1%) apresentavam neuropatia uni ou bilateral do nervo mediano, 4 (28,6%) radiculopatias e 3 (21,4%) PNP. Parestesias/dores neuropáticas nos membros sem sinais objetivos de NP foram relatadas por 26,3% dos pacientes e por 7,9% dos controles (p < 0,0001). Não houve diferença significativa na prevalência de diabetes melito (DM) entre pacientes e controles (6,6% vs 9,2%). Dezessete pacientes (22,4%) tinham intolerância à glicose. CGs foram detectadas no soro de 9,2% (6/65) dos pacientes e foram positivas no soro de 13,8% dos pacientes portadores de HCV com NP. Teor aumentado de gamaglobulinas séricas foi encontrado em 46,2% (30/64) dos pacientes, positividade do FR em 26,7% (16/60), níveis baixos de C4 em 19,3% (16/60), anticorpos (AC) antimúsculo liso em 26,2% (18/65), AC antitireoperoxidade em 22,9% (8/35) e AC anticardiolipinas IgM em 20,7% (12/58). Houve diferença estatística significativa entre pacientes com hepatite C com e sem NP em relação à presença de AC anti-SSA/RO e antitirosina fosfatase (p=0,028 e p=0,038, respectivamente). Nos pacientes com hepatite C, NP se correlacionou com idade (p < 0,05), grau de fibrose à biópsia hepática (p < 0,05) e alteração do metabolismo da glicose (p < 0,05) e no grupo controle com o diagnóstico de DM (p < 0,01). Não foram verificadas diferenças estatísticas significativas entre pacientes e controles em relação aos escores totais no MEEM, FV semântica, TDR e testes dos dígitos em ordem direta e indireta. A memória de evocação mostrou diferença significativa entre os grupos (p=0,009). Mais pacientes que controles tinham escores <= 23 no MEEM (p=0,025). Resultados semelhantes foram obtidos na comparação entre sujeitos com escolaridade > 4 anos. Não foi verificada diferença estatística entre pacientes e controles em relação ao grau de depressão, ansiedade e desesperança. Os genótipos do HCV não se correlacionaram com nenhuma variável estudada. Conclusão: 38,1% dos pacientes e 18,3% dos controles apresentavam NP. MN ou MNM representaram 41,3%, as PNP 24,1% e as PNP com MN ou MNM sobrepostas 17,2%. Nos pacientes com hepatite C as NP mostraram correlação com AC anti-SSA/RO e antitirosina fosfatase. Foi verificada diferença significativa entre os grupos na memória de evocação e no número de sujeitos que obtiveram escores <= 23 no MEEM, mas não quanto aos sintomas de depressão, ansiedade e desesperança / Background: Chronic hepatitis C virus (HCV) infection is increasingly considered a systemic disease with numerous extrahepatic manifestations. Peripheral neuropathies (PN) and neuropsychiatric disorders are reported in some series of patients, with a certain heterogeneity between them. Although cognitive dysfunction has been described, some studies failed to prove this association. Few studies on the subject were conducted in Brazil. Objectives: identify disorders in peripheral nerve function and neuropsychiatric dysfunction in treatment-naïve patients with chronic HCV infection without overt hepatic encephalopathy and verify whether there is a relationship with viral genotype, liver fibrosis grade and presence of autoantibodies. Methods: a cohort of 76 adult patients with chronic HCV infection aged 18 years and older (40 women), treatment naïve, not coinfected with hepatitis B virus (HBV), acquired immunodeficiency virus (HIV) or syphilis was evaluated from August 2009 to February 2016 and compared with a control group of 76 individuals (43 women) with a negative screening for HCV, HBV, HIV or syphilis, with similar gender, age and educational level distribution. Patients and controls were clinically evaluated and submitted to a brief cognitive screening (Minimental State Examination (MMSE), clock drawing test (CDT), semantic verbal fluency test (VF) and digit span test (WAIS-III) in direct and inverse order and assessment of mood, anxiety and hopelessness through the Beck Inventory. Hepatitis C patients underwent extensive battery of laboratory tests, genotype determination, insulin dosage, and gammaglobulins, cryoglobulins (CGs), rheumatoid factor (RF), complement fractions, and autoantibody screening. Anatomopathological studies of the liver performed within less than 18 months of the initial study interview were considered for analysis. The Statistical Package for the Social Sciences was used to carry out appropriate tests. Results: PN was found in 29 patients with HCV infection (38.1%) and 14 controls (18.3%) [p = 0.007]. Of the HCV patients with PN, 12 (41.4%) presented MN or MNM, 7 (24.1%) sensory or sensoriomotor PNP, 5 (17.2%) PNP with MN or MNM overlap, 4 (13.8%) radiculopathies and 1 (3.4%) pure motor neuropathy. Of the 14 control subjects with PN, 8 (57,1%) had uni or bilateral medial nerve neuropathy, 4 (28.6%) radiculopathy and 3 (21.4%) PNP. Paresthesias / neuropathic limb pain without objective signs of PN were reported by 26.3% of patients and 7.9% of controls (p < 0.0001). There was no significant difference in the prevalence of diabetes mellitus (DM) between patients and controls (6,6% vs 9,2%). Glucose intolerance was found in 17 (22.4%) HCV patients. Serum CGs were detected in 9.2% (6/65) of the HCV patients and were positive in 13.8% of HCV patients with PN. High serum gamma globulins levels were found in 46.2% (30/64) of the patients, FR in 26.7% (16/60), low C4 levels in 19.3% (16/60), smooth muscle antibodies in 26.2% (18/65), anti-thyroperoxidase antibodies in 22.9% (8/35) and IgM anticardiolipin antibodies in 20.7% (12/58). Anti-SSA / RO and anti-tyrosine phosphatase antibodies were significantly different between HCV patients with and without PN (p = 0.028 and p = 0.038, respectively). PN in HCV patients was correlated with age (p < 0.05), grade of liver fibrosis (p < 0.05) and altered glucose metabolism (p < 0.05) and in the control group with DM (p < 0.01). No statistically significant differences between patients and controls were found in the total scores of MMSE, semantic VF, TDR and digit tests in direct and indirect order. Recall memory showed a significant difference between the groups (p = 0.009). More patients than controls had scores <= 23 in the MMSE (p = 0.025). Similar results were obtained in the comparison between subjects with > 4 years of schooling. No statistical difference was found between patients and controls regarding the degree of depression, anxiety and hopelessness. HCV genotypes did not correlate with any of the studied variables. Conclusion: 38.1% of the patients and 18.3% of the controls had NP. In HCV patients with PN, MN or MMN represented 41.3%, PNP 24.1% and PNP with MN or MMN superimposed 17.2%. Anti-SSA/RO and antityrosine phosphatase antibodies showed a significant difference between HCV patients with and without PN. There was a significant difference between the groups in recall memory and in the number of subjects who obtained scores <= 23 in the MMSE, but not in the symptoms of depression, anxiety and hopelessness

Approximately 43% of college students report experiencing suicidal ideation in the past year, and suicide is the 2nd leading cause of death among college students, making it a significant public health concern. Development of successful suicide intervention and prevention strategies is predicated on identification of risk (e.g. negative life events, hopelessness) and protective factors (e.g. self-compassion) that may be targeted for treatment. A well-established linkage exists between life stressors and suicidal behavior; however, potential mechanisms of action underlying this association are under-researched. It may be that negative life events contribute to feelings of hopelessness, which is conceptualized as negative beliefs and expectations about one’s self and future. However, not all persons who experience negative life events and hopelessness become suicidal, perhaps due to protective factors such as self-compassion. Comprised of self-kindness, mindfulness and sense of common humanity, self-compassion may contribute to emotional resilience when negative life events occur; however, this premise has not been previously examined. We hypothesized that hopelessness would mediate the relation between negative life events and suicidal behaviors, such that negative life events would be related to increased feelings of hopelessness and, in turn, to greater risk for suicidal behavior. We also hypothesized that self-compassion would beneficially moderate the mediating effect of hopelessness. Our sample of college students (n=338) were primarily female (67%; n=227) and White (89.6%; n=294), with a mean age of 21.8 years (SD=4.7). Participants completed self-report measures including the Life Events Scale, the Beck Hopelessness Inventory, the Suicide Behaviors Questionnaire - Revised, and the Self-Compassion Scale. Supporting our hypotheses, hopelessness fully mediated the relation between negative life events and suicidal behavior (DE=.07, SE=.06, 95% CI=.05,.28,p

Suicide represents a major problem for all members of society. Findings from studies have shown that suicide risk is among the highest in young adult populations. Although a variety of factors have been identified in trying to predict suicide risk in young adults, one variable that has received considerable attention has been social disconnectedness. For example, according to Joiner’s (2005) theory of suicide, being socially disconnected from others represents a critical factor that heightens a person’s risk for suicide. Consistent with this view, findings from numerous studies have shown a reliable association between loneliness and suicide risk (Hatcher & Stubbersfield, 2013). For example, Chang and his colleagues (Chang et al., 2015; Chang, Muyan, & Hirsch, 2015; Muyan & Chang, 2015) have found a reliable association between loneliness and greater suicide risk (e.g., hopelessness, suicidal behaviors) in diverse cultural groups. Indeed, in one study, Chang, Hirsch, Sanna, Jeglic, and Fabian (2011) found that loneliness was an important predictor of suicide risk in Latina college students. Although these findings are important and point to the potential value of loneliness as a predictor of suicide risk in diverse adult groups, they do not take into account more culture- specific variables. Accordingly, we conducted the present study to examine the extent to which culture- specific (emic) variables might play an important role in predicting suicide risk, and to also determine if the inclusion of a general (etic) explanatory variable would add to the prediction of suicide risk, namely, hopelessness and suicidal behaviors, in a sample of 155 Latino college students. We conducted a pair of regression analyses including demographic variables (viz., age & sex) in the First Step, ethnic identity variables (ethnic affirmation, ethnic identity achievement, ethnic behaviors, & other group orientation; Phinney, 1992) in the Second Step, and loneliness (Russell, Peplau, & Curtrona, 1980) in the final Third Step, in predicting hopelessness and suicidal behaviors. Results of these analyses for both outcomes indicated that demographic variables did not account for significant variance in suicide risk. However, ethnic identity variables, as a set, were found to account for a significant 11% of the variance in hopelessness, and a significant 10% of the variance in suicide behaviors. Noteworthy, the inclusion of loneliness was found to account for an additional 19% of unique variance in hopelessness, and an additional 13% of unique variance in suicidal behaviors. Taken together, our findings underscore the importance of considering both emic and etic factors in trying to identify variables that may place Latinos at heightened risk for suicide. Additionally, our findings also point to the potential value of targeting specific ethnic identity variables (e.g., ethnic identity achievement) as well as loneliness when working with Latinos at risk for suicide.

目的　本研究嚐試探討無望感與未來思考及情緒困擾間的關係，旨在驗證MacLeod的未來思考研究，以及區分病例組與對照組的敏感性。 研究對象　非病人樣本，主要為大學生以及部分社會人士，共123名；病人樣本則為台北巿立萬芳醫院的門診病患，共49名。 研究方法　非病人樣本採用隨機取樣，病人樣本採用隨機立意取樣之病例對照研究設計。 研究材料　包括「貝克無望感量表」、「貝克焦慮量表」、「貝克憂鬱量表第二版」、「語意歷程作業」、「語文流暢作業」、與「未來思考作業」共六項。 研究結果　本研究結果符合MacLeod先前的研究結果為，即(1)無望感與正向未來思考的減少有關；與(2)憂鬱與正向未來思考的減少，及負向未來思考的增加有關。不符合MacLeod的研究果為：焦慮與未來思考的關係不顯著。另外，以「正向未來思考」及「負向未來思考」來區分病人與非病人就目前的樣本而言，是不具有敏感性的。 結論　對於臨床工作而言，須注意正向未來思考減少對個案的影響，並進一步的給予適宜的處置，以預防疾病的再發。 關鍵字　無望感、正向未來思考、負向未來思考、情緒困擾

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In the United States, there is a high incidence of recidivism among juvenile offenders with mental health disorders. This is a critical social issue facing the public and the Department of Juvenile Justice Administration today. However, research is not clear on the role of psychological factors in recidivism frequency and survival time. The purpose of this study was to examine whether hopelessness depression, as measured by suicidal-ideation, depression-anxiety, anger-irritation, and alcohol-drug use, and offense type, were predictors of recidivism frequency and survival time when controlling for age, gender, and race. The total sample consisted of archival data from 404 juvenile offenders between the ages 13 and 19, who were detainees in the Juvenile Detention facility between January 1, 2009, and December 31, 2012. Data consisted of scores from the Massachusetts Youth Screening Instrument, which is part of the standard intake screening at time of booking. A hierarchical regression analysis indicated a collective significant predictive relationship between age, gender, race, suicidal-ideation, depression-anxiety, anger-irritation, alcohol-drug-use, and recidivism frequency and survival time. Posthoc analyses of variance indicated statistically significant differences in alcohol-drug-use and anger-irritation levels between races. However, the multiple linear regression indicated that suicidal-ideation and depression-anxiety did not significantly predict either recidivism frequency or survival time. Results could enable juvenile justice staff to detect hopelessness depression among juvenile reoffenders at an earlier stage and offer better treatment aimed at reducing future occurrences of youth recidivism, thereby benefitting individuals as well as society.

In this study of Lev Shestov, the biographical method is used to explain his philosophy. The grave crisis or nervous breakdown Shestov went through caused a total transformation of his - convictions and values. It was probably this drama that led to his repudiation of the common life and traditional philosophy with its emphasis on reason, knowledge, and ethics in favour of an extreme individualism and religious transcendence. The aim of the dissertation is to examine, amongst the great number of philosophers and writers Shestov analysed, mainly those in his view “marginal thinkers”, who were of the greatest interest to him – Fyodor Dostoevsky, Lev Tolstoy, Friedrich Nietzsche, Martin Luther, and Søren Kierkegaard. On the basis of this analysis the character of Shestov’s philosophy is defined. According to Shestov, like his own crisis, the crises that these thinkers experienced occasioned a total transformation of their convictions and values. Šestov does not let his life find complete expression in his philosophy. Instead he projects his crisis into the five thinkers’ crises and philosophy. To characterize the previous and new modes of thinking, the concepts of alienation (degeneration, degradation, depravity) and authenticity (deliverance from alienation) are used. Shestov’s judgment of the consistency of the five thinkers’ new attitudes is presented, i.e. deliverance from the common life with its emphasis on rational eternal truths and moralism. Authentic life is in Shestov’s opinion the from the individual’s everyday life concealed experience of despair in extreme situations. This constitutes a grave crisis that leads to the repudiation of all hitherto held convictions and cherished hopes. The contrast between the Russian philosopher’s personal, (after his crisis) mainly tranquil, harmonious life and his philosophy is glaring. Analyzing the five thinkers, Shestov finds that they did not persevere with their new convictions, instead they complied with the by everybody accepted and everywhere valid truths. Shestov’s “theoretical”, uncompromising and consistent stance on one side and the lack of these characteristics with the aforementioned thinkers on the other side, to a great extent places Shestov in another category than these. In Shestov’s view freedom is in the region of tragedy, which nobody enters on his own will and in the incomprehensible trust in a capricious, “inhuman” God. According to Shestov, only the philosopher, who derives his thinking from a situation, where he experiences extreme despair and hopelessness, can claim to be a true philosopher. / <p>Examinator: docent Julie Hansen; Uppsala universitet</p>