La presente investigación evalúa la viabilidad de un nuevo servicio de laboratorio dental digital con tecnología 3D para el diseño y confección de prótesis dentales como propuesta para reducir los dolores actuales de los clientes, en este caso odontólogos y técnicos dentales; brindando asesoría y soporte técnico a lo largo del proceso.  Los servicios existentes en el mercado actual ofrecen un producto trabajado bajo un procedimiento artesanal que, al involucrar varios pasos, más de un actor dentro del proceso y varios mini procesos manuales tanto en la fase preparatoria (clínica) y técnica; está expuesto a errores y lleva a los actores a tiempos de trabajo prolongados. Por lo mismo, la calidad de una prótesis trabajada bajo un proceso artesanal, es decir, el ajuste y precisión, color exacto y estética; muchas veces se ve afectada ocasionando a los clientes (odontólogos) una mala experiencia y el retraso por el reproceso que suele darse y a los usuarios finales (pacientes) una mala experiencia con la prótesis adquirida y la no satisfacción con el resultado final.   Este servicio trabajado bajo proceso artesanal actualmente es ofrecido en su mayoría por técnicos dentales de manera particular y en muchos casos, informal. Actualmente no existe una empresa que brinde un servicio integral en el que las impresiones sean trabajadas de manera digital o que brinde un respaldo y seguridad.  Para validar la idea de negocio se realizó una encuesta cuantitativa y entrevistas a profundidad y según el análisis de los resultados, se concluye que el desarrollo del laboratorio digital DentalTec, es viable. La fuente primaria estuvo conformada por más de 50 odontólogos de Lima Metropolitana. Con ello se evidenció que la propuesta de valor es atractiva para el público objetivo, al ofrecer mejores indicadores relevantes para ellos: menor tiempo, mayor ajuste y mejor estética.  La propuesta de valor del laboratorio digital DentalTec está centrada en la impresión digital que ofrecerá como parte de todos los servicios. Se reemplaza el proceso tradicional artesanal, eliminando así reprocesos, errores humanos y largos tiempos de atención. Permitiendo a su vez a nuestros clientes, poder contar con un servicio de confianza que cumplirá con las fechas pactadas, con prótesis dentales de calidad y un mayor número de clientes atendidos en una menor cantidad de citas programadas.  Finalmente, respecto al análisis financiero y a la proyección de ventas, en el escenario optimista se espera llegar a una cobertura del 2% del mercado en el primer año y a más del 10% en el quinto año, se logra un TIR del 159.4% cuando el COK de la empresa es 11%. Además, el VAN sería de S/.10,589,582 soles. De igual manera, en el escenario pesimista, se lograría un TIR superior al COK. Datos que nos llevan a apostar por este proyecto. / This research evaluates the feasibility of a new digital dental laboratory service with 3D technology for the design and manufacture of dental prostheses as a proposal to reduce the pain of current clients, in this case dentists and dental technicians; providing advice and technical support throughout all process. The services in the current market offer a product with an artisan procedure that involve several steps and more than one actor in the process. Therefore, the quality of a prosthesis worked under an artisan process it is affected with a wrong fit and precision, exact color and aesthetics. Clients (dentists) and users (patients) are not being satisfied with the final result. This service under the artisan process is currently offered mostly by dental technicians in an informal way. Currently there is no company that provides a service in which prints are worked digitally and provides security of a good result. To validate the business idea, we work with quantitative survey and interviews. Based on the analysis of the results, the development of DentalTec digital laboratory is viable. The quantitative survey was made in more than 50 dentists from Lima. This evidenced that DentalTec services are attractive to the target audience, offering better relevant indicators for them as less time, better fit and aesthetics. The value proposal of the DentalTec digital laboratory is focused on digital printing with personalized services. The traditional artisan process is replaced, and it will eliminate reprocessing, human errors and long times. At the same time, clients will have a trustworthy service with deadlines, with quality dental prostheses and an important number of clients attended in less appointments. Finally, regarding the financial analysis and the sales projection, in the optimistic scenario it is expected to reach a coverage of 2% of the market in the first year and more than 10% in the fifth year, an IRR of 159.4% is achieved when the company's opportunity cost is 11%. In addition, the NPV would be S /. 10,589,582 soles. In the same way, in the pessimistic scenario, an IRR higher than the opportunity cost would be achieved. Data that leads us to bet on this project. / Trabajo de investigación

Prospective memory (PM) refers to a person’s ability to remember to do something in the future. It is a complex behaviour that is essential for the daily functioning of young and old alike. Despite its importance in everyday life, few studies have sought to examine the role of personality on PM performance using a multi-trait multi-method approach in young adults. The current study aimed to investigate the differential roles of the Big 5 personality traits on event- and time-based PM performance using multiple measurement methods. In addition, the study aimed to add to the current PM and personality literature by addressing several of the identified methodological limitations of the literature as outlined by Uttl and colleagues (2013). Results demonstrated few strong relationships between PM subtypes (event and time-based) performance indicators, though performance on the lab-based event-based PM task was stronger than on the lab-based time-based PM task even after controlling for ongoing task performance. Participants were also found to perform better on lab-based rather than naturalistic PM tasks. Naturalistic and self-report PM measures were significantly related to each other, but not to lab-based PM. Regarding personality, the relationship between specific personality traits and PM performance differed depending on the PM subtype and/or measurement method being investigated with conscientiousness, memory aid strategy use, and substance use engagement being found to best predict self-reported PM errors in daily life. The current study demonstrated that each PM measurement method taps into different aspects of behavioural and cognitive functioning. Without the use of all three measurement methods, whilst also considering the individuality of the client, researchers and clinicians may be doing a disservice to individuals with true PM difficulties as they may overlook important factors contributing to their poorer performance. / Graduate

Libraries have quietly changed over the last 20 years. They have adapted early and consciously to the changes of digitalization, they have recognized the changed need of their users for collaborative work and derived new spatial concepts from this. Transparency and access to information, knowledge and encounters are the prerequisites for holistic social development. It is the challenge of the 21st century as the information age.

No description available.

Il presente contributo illustra una posizione sul ruolo dei modelli e della modellizzazione nel contesto del Research Software Engineering (RSE) nelle Digital Humanities (DH). La nostra ipotesi è che all'interno del contesto nel quale opera il King’s Digital Lab, influenzato da fattori storici e di gestione manageriale, la produzione di modelli è di fatto il contributo essenziale dell'RSE all'epistemologia di DH. Tuttavia, riteniamo che quando considerate da una prospettiva di RSE olistica, che include - pur non essendo ad essa limitata – la modellizzazione empirica e predittiva, queste attività di modellizzazione non siano state studiate in modo abbastanza sistematico da supportare a pieno questa posizione. Il nostro contributo può soltanto indicare qualche idea e abbozzare un approccio che meriterebbero ricerche più approfondite / This paper1 offers a position on the role of models and modelling in the context of Research Software Engineering (RSE) in Digital Humanities (DH). Our hypothesis is that within the context that King’s Digital Lab operates, shaped by historical and management factors, the production of models is arguably the core contribution of RSE to the epistemology of DH. However, we argue that, when analysed from a holistic RSE perspective, encompassing but not limited to empirical and predictive modelling, these modelling activities have not been studied systematically enough to support such a claim in straight-forward ways. Our contribution can only gesture at some ideas and sketch a framework that would need further research.

No description available.

Unmanned vehicle systems, specifically unmanned air vehicles (UAVs) and unmanned ground vehicles (UGVs), have become a popular research topic. This thesis discusses the potential of a UAV-UGV system used to track a human moving through complex urban terrain. This research focuses on path planning problems for both a UAV and a UGV, and presents effective solutions for both problems. In the UAV path planning problem, we desire to plan a path for a miniature fixed-wing UAV to fly through known urban terrain without colliding with any buildings. We present the Waypoint RRT (WRRT) algorithm, which accounts for UAV dynamics while planning a flyable, collision-free waypoint path for a UAV in urban terrain. Results show that this method is fast and robust, and is able to plan paths in difficult urban environments and other terrain maps as well. Simulation and hardware tests demonstrate that these paths are indeed flyable by a UAV. The UGV path planning problem focuses on planning a path to capture a moving target in an urban grid. We discuss using a target motion model based on Markov chains to predict future target locations. We then introduce the Capture and Propagate algorithm, which uses this target motion model to determine the probabilities of capturing the target in various numbers of steps and with various initial UGV moves. By applying some different cost functions, the result of this algorithm is used to choose an optimal first step for the UGV. Results demonstrate that this algorithm is at least as effective as planning a path directly to the current location of the target, and that in many cases, this algorithm performs better. We discuss these cases and verify them with simulation results.

Detta examensarbete undersöker om ett skolprogram på Vetenskapens Hus har förmågan att skapa en bro mellan gymnasieelevers matematikkunskap, universitetsmatematik och dess praktiska tillämpning för att därmed öka deras intresse och motivation för inlärning av matematik- och fysikämnen. Skolprogrammets tema är fourieranalys och dess tillämpning inom ljudsyntes och digital ljudbehandling (DSP). Skolprogrammet har att göra med matematik, fysik och IT, vilket gör programmet tvärvetenskapligt. En viktig del av detta arbete är också att vidareutveckla detta skolprogram med avseende på resultaten från denna undersökning. Resultaten är baserade på kvalitativa data från enkäter och intervjuer med eleverna som deltog i testfallen av skolprogrammet och deras lärare samt på litteraturstudier. Information samlades också in under en iterativ process av programmets vidareutveckling. Denna rapport inleds med motivering till genomförandet av detta arbete, studiens syfte- och målsättning samt formulering av huvudfrågeställningar. Därefter beskrivs metoder som användes för att besvara frågeställningarna. I mitten av rapporten sammanfattas litteratur och forskningsstudier inom undervisning, intresse och motivation samt sammanfattas en vetenskaplig bas för innehållet i skolprogrammet inom fourieranalys. Därefter beskrivs utvecklingsprocessen av skolprogrammet. Detta följs av en presentation av resultaten från testning av skolprogrammet med gymnasieelever med avseende på hur deras intresse och motivation påverkas av det. Rapporten avslutas med diskussion av dessa resultat och dess trovärdighet. Resultaten visar att den sista versionen av den laborativa aktiviteten, som vidareutvecklades inom ramen av detta arbete, väcker elevernas intresse och motivation för temat av skolprogrammet. Resultaten visar också att vissa komplexa begrepp (både nya och de som eleverna lär sig i skolan) blir klarare för eleverna efter skolprogrammet, vilket potentiellt kan leda till ökning av deras motivation till att lära sig matematik och naturvetenskap generellt. Problemet är dock att skolprogrammet testades med för få gymnasieklasser för att kunna generalisera resultatet över hela målgruppen av gymnasieelever. / This thesis investigates the ability of a lab exercise in House of Science (Vetenskapens Hus),Stockholm, to create bridges between upper-secondary school students’ knowledge, university mathematics and practical application of that knowledge, thus increasing their motivation and interest to learn more mathematics and physics. The topic of the lab exercise is Fourier analysis and its practical application in Digital Sound Processing (DSP). The lab exercise deals with mathematics, physics and IT-technology thus making the activity interdisciplinary. An important part of the work is also to improve this lab exercise based on the results of this study. The result is based on qualitative data from interviews, questionnaires filled by students and their teachers and also on literature studies. Some data is also collected through an iterative process of improving the lab exercise. This report starts with justification for conducting this work, setting the goals and objectives and formulating main questions. Then the methods, which were used in order to answer these questions, are described. The middle part of the report summarizes literature and research studies in education, interest and motivation of students and also summarizes a scientific basis for the content of the school program in Fourier analysis. Next, the development process of the school program is described. This is followed by a presentationof the results of testing the school program with upper secondary school students with regard to how their interest and motivation are affected by it. The report ends with a discussion of these results and its credibility. The result shows that the final version of the lab exercise, that is modified within the framework of this study, wakes students’ interest and motivation towards the topic of the exercise. The result also shows that some complex concepts (both new and those which are learned in school) become clearer for the students after the exercise which could potentiallylead to an increase in their motivation for learning the mathematics and physics in general. The problem is that the lab exercise was tested on too few classes for being able to generalize the result over the whole target group of the upper-secondary school students.

The rise of superbugs, including antibiotic-resistant bacteria, and virus outbreaks, such as the recent coronavirus scare, illustrate the need for rapid detection of disease pathogens. Widespread availability of rapid disease identification would facilitate outbreak prevention and specific treatment. The ARROW biosensor microchip can directly detect single molecules through fluorescence-based optofluidic interrogation. The nature of the microfluidic channels found on optofluidic sensor platforms sets some of the ultimate sensitivity and accuracy limits and can result in false negative test results. Yet higher sensitivity and specificity is desired through hydrodynamic focusing. Novel 3D hydrodynamic focusing designs were developed and implemented on the ARROW platform, an optofluidic lab-on-a-chip single-molecule detector device. Microchannels with cross-section dimensions smaller than 10 μm were formed using sacrificial etching of photoresist layers covered with plasma-enhanced chemical-vapor-deposited silicon dioxide on a silicon wafer. Buffer fluid carried to the focusing junction enveloped an intersecting sample fluid, resulting in 3D focusing of the sample stream. The designs which operate across a wide range of fluid velocities through pressure-driven flow were integrated with optical waveguides in order to interrogate fluorescing particles and confirm 3D focusing, characterize diffusion, and quantify optofluidic detection enhancement of single viruses on chip.

Kommunala avloppsreningsverk renar avloppsvatten och avlägsnar näringsämnen innan vattnet släpps ut i den omgivande miljön. Under reningen avskiljs partiklar som bildar råslam. Genom att bryta ner råslammet anaerobt (syrefritt) via rötning kan användbara produkter, såsom biogas till bussar, erhållas. Rötning innebär att organiskt material bryts ner under kontrollerade former. Sveriges tredje största kommunala avloppsreningsverk är Käppalaverket i Stockholm. Framtidsprognosen för verket visar att belastningen kommer öka, samtidigt förväntas kraven på slamhantering bli strängare.  Syftet med denna studie var att utreda en metod för att öka Käppalaverkets slambehandlingskapacitet. Idag rötas slammet konventionellt med mesofil rötning. Ett förslag för att öka kapaciteten är att förtjocka och därefter recirkulera slammet in i samma rötningskammare. Möjliga fördelar med detta kan vara ökad biogasproduktion samt möjlighet till högre belastning i rötkamrarna.  Till experimentet nyttjades en pilotanläggning bestående av två rötkammrar på 7 dm3. Rötkamrarna användes för att studera konventionell mesofil rötning (i studien benämnd BR01), jämfört med mesofil rötning med recirkulering (i studien benämnd BR02). Råslammet och rötslammet analyserades löpande (på dag- och veckobasis) med avseende på parametrarna: biogasproduktion och gassammansättning, torrsubstanshalt, halt av flyktiga syror, pH, alkalinitet, organisk belastning, andel mineraliserat kväve, utrötningsgrad samt reduktion av makromolekyler. Uppehållstiden (HRT) för slammet i rötkamrarna var inledningsvis 14 dagar. HRT sänktes stegvis  under studien (från 14 till 11 dagar och därefter till 9 dagar) genom att inflödet av råslam ökades. Därmed pressades BR01 och BR02 i syfte att utröna vid vilken belastning rötningsprocessen förändrades från stabil till instabil. Resultaten visade att under 11-dagars perioden var processen i BR01 stabilare än i BR02. Förhöjda halter av flyktiga syror uppmättes i BR02 under denna period. Under 9-dagars perioden med högre belastning observerades att processen i BR01 var instabil. Processen i BR02 var stabilare under samma period och ansågs därför prestera bättre under högre belastning. Statistiska t-tester visade att flertalet reaktorparametrar (i en och samma reaktor) genomgick säkerställda förändringar från experimentets start till slut. / Municipal wastewater treatment plants (WWTPs) purifies wastewater from nutrients before releasing it to the recipient. Particles that are separated from the water creates a sewage sludge. Anaerobic (without oxygen) digestion is mainly used as a stabilization method for the sludge. Digestion of the sludge produces energy-rich biogas and a nutrient-rich digestate which can be used as a fertilizer. The third largest municipal WWTP in Sweden is Käppala WWTP, situated in Stockholm. In the future, the amount of incoming wastewater is expected to increase. Simultaneously, regulations regarding sludge management are expected to be stricter. The main purpose of this study was to investigate a method to increase the sludge load to the digesters at Käppala WWTP. Today the sludge is digested conventionally with mesophilic anaerobic digestion. One suggestion is to recirculate thickened sludge into the same digestion reactor. This method has been shown to give an increased biogas production as well as improved digester performance.   During the experiment a pilot-digester consisting of two anaerobic reactors (each with a volume of 7 dm3) were used. These reactors were used to study conventional mesophilic digestion (BR01 in this study) and mesophilic digestion with sludge-recirculation (BR02 in this study). Several parameters of the sludge (raw and digested) were analysed on daily and weekly basis: biogas production and gas composition, dry matter content, volatile fatty acids, pH, alkalinity, organic loading, mineralised nitrogen, degree of digestion and reduction of macromolecules. The hydraulic retention time (HRT) of the sludge was initially 14 days. HRT was lowered stepwise (from 14 to 11 and finally down to 9 days) by increasing the inflow of raw sludge. This way the two reactors were pushed to see at what point the digestion process became unstable. The results showed that during the 11-days HRT period BR01 was more stable compared to BR02. Heightened VFA-content was measured in BR02 during this period. During the 9-days HRT period the process in BR01 was deemed unstable. The process in BR02 was more stable during the same period and was considered to have a better performance during high sludge inflow. Statistical t-tests showed that several digestion-parameters (compared for the same reactor) underwent statistically significant changes from the start to the end of the experiment.