Assim como a medicina, a psiquiatria não consiste em uma disciplina teórica, mas sim, em uma práxis, um projeto teórico que somente se justifica pelo projeto prático. Trata-se, portanto, de um campo de intervenção. A psiquiatria utiliza diversas abordagens teóricas e científicas com uma finalidade prática. O objeto de estudo do campo, entretanto, não se confunde com o objeto destas abordagens. O objeto da psiquiatria pode ser definido em vertentes reducionistas e não-reducionistas. No contexto atual, há uma tendência a uma polarização. Por um lado, o objeto da psiquiatria é concebido como o objeto das demais especialidades médicas, enquanto doença mental, localizado no cérebro e resultando em práticas que privilegiam as abordagens biológicas. Por outro, em vertentes mais amplas de definição, ele consiste no sofrimento psíquico e social ou em disfunções internas socialmente inapropriadas, o que envolve múltiplos níveis e dimensões biológico, fenomenológico, cultural. Esta concepção do objeto da psiquiatria demanda uma multiplicidade e pluralidade de abordagens tanto no plano teórico quanto no plano prático. A presente tese afirma que uma perspectiva multinível e plural é imperiosa à práxis psiquiátrica. A tese está dividida em duas partes. Na primeira, realiza-se uma discussão filosófica na psiquiatria, mediante o método da investigação conceitual, visando um refinamento teórico do campo, que tende a gerar práticas mais efetivas. Três problemas filosóficos que perpassam a psiquiatria são discutidos: a distinção explicação-compreensão; o problema mente-cérebro e a distinção fato-valor. Aponta-se uma solução pragmatista para cada um destes problemas. Na segunda parte, realiza-se um estudo de caso com o exemplar esquizofrenia, analisando os múltiplos níveis do fenômeno mediante a apresentação das abordagens biológicas, fenomenológicas e antropológicas da esquizofrenia na contemporaneidade, enfocando, respectivamente, as hipóteses neurodesenvolvimentais, as alterações na consciência pré-reflexiva de si e as concepções do fenômeno em contextos não-ocidentais. A esquizofrenia corresponde a uma categoria de alta validade, tendo uma importante participação de fatores genético-biológicos. Ainda assim, o modelo biomédico se mostra insuficiente para dar conta da complexidade da experiência do adoecimento nesta condição. Portanto, uma perspectiva multinível e plural se faz mandatória. E se esta perspectiva se aplica à esquizofrenia, aplicar-se-á também a todos os transtornos mentais, com importantes implicações para a práxis psiquiátrica, seja no âmbito da teoria e pesquisa, seja no âmbito da clínica e da elaboração de políticas públicas de saúde mental, ajustando-se melhor, por exemplo, aos propósitos do Global Mental Health. / Just as medicine, psychiatry does not consist in a theoretical discipline, but in praxis, a theoretical project that is only justified by practical project. Therefore, it is a field of intervention. Psychiatry uses various theoretical and scientific approaches with a practical purpose. However, the subject of this field cannot to be confused with the subject of these approaches. The subject of psychiatry can be defined in reductionist and non-reductionist strands. In the current context, there is a tendency to polarization. On the one hand, the subject of psychiatry is conceived as the subject of other medical specialities, as a mental disease, located in the brain and resulting in practices that favor biological approaches. On the other hand, in broader strands of definition, it consists on psychic and social suffering or socially inappropriate internal dysfunctions, which involves multiple levels and dimensions - biological, phenomenological, cultural. This conception of the subject of psychiatry demands a multiplicity and plurality of approaches in both theoretical and practical plans. This thesis affirms that a multilevel and plural perspective is imperative to psychiatric praxis. The thesis is divided into two parts. In the first part, there is a philosophical discussion in psychiatry, by the method of conceptual investigation, aiming a theoretical refinement of the field, which tends to generate more effective practices. Three philosophical problems that pass through psychiatry are discussed: the explanation-understanding distinction, the mind-brain problem and the fact-value distinction. A pragmatist solution for each of these problems is pointed. In the second part, there is a case study of schizophrenia as exemplar, analyzing the multiple levels of the phenomenon upon presentation of biological, phenomenological and anthropological approaches to schizophrenia in contemporary times. This case study is focusing on neurodevelopmental hypothesis, changes in pre-reflective self-consciousness and conceptions of the phenomenon in non-Western contexts, respectively. Schizophrenia represents a category of high validity, with an important contribution of genetic-biological factors. Still, the biomedical model is insufficient to account for the complexity of the experience of suffering this condition. Therefore, a multilevel and plural perspective becomes mandatory. And if this perspective applies to schizophrenia, also will apply to all mental disorders, with important implications for psychiatric praxis, either within the theory and research, either within the clinical and mental health policy development, adjusting better, for example, to the purposes of the Global Mental Health.

Introdução: Os neuropeptídeos regulam uma variedade de aspectos da função nervosa e neuroendócrina, atuando através da ativação de receptores específicos da membrana celular. No sistemana nervoso central (SNC) os receptores do pepetídeo liberador de gastrina (GRPR) são amplamente expressos, e numerosos efeitos centrais têm sido descritos com a sua ativação, incluindo efeitos sobre a saciedade, regulação do ritmo circadiano, termorregulação, modulação do stress, resposta ao medo, ansiedade e memória. Pesquisas mostram que o bloqueio farmacológico do GRPR em modelos animais leva ao aparecimento de deficits na interação social, padrões restritivos de comportamento e estereotipias motoras, sintomas semelhantes ao comportamento autista em humanos, sugerindo a possibilidade de que o complexo GRP/GRPR possa ter um papel na patogênese do transtorno do espectro autista (TEA). Recentemente, dois estudos não controlados com administração do peptídeo liberador de gastrina (GRP) a 13 crianças com autismo sugeriram que ele é seguro e que possa melhorar alguns sintomas do transtorno, principalmente interação social e sintomas associados à irritabilidade. Objetivos: Comparar a eficácia, segurança, tolerabilidade do GRP em relação ao placebo em sintomas do TEA. Metodologia: Ensaio clínico crossover, randomizado, duplo-cego, controlado por placebo, com uso de GRP 160 picomol/kg por 4 dias consecutivos, em 10 crianças com autismo. Os desfechos foram medidos através da escala Aberrant Behavior Checklist (ABC). Resultados: Todos os participantes eram do sexo masculino, com idade entre 4 e 9 anos. Houve uma redução nos escores da escala ABC e suas subescalas após o uso de GRP e de placebo. Apesar dessa redução ser mais proeminente com o GRP, principalmente nas subescalas Irritabilidade, Comportamento estereotipado e Hiperatividade, não houve diferença estatística entre os resultados (p 0,334). Após uma semana da infusão, 5 crianças apresentavam melhora maior que 25% no escore total da escala ABC com uso de GRP e 2 com uso de placebo, não apresentando diferença estatística (p 0,375). Não houve efeitos adversos, alterações dos sinais vitais ou variações laboratoriais associados ao uso de GRP em nenhum paciente. Conclusões: Os resultados deste estudo, apesar do tamanho reduzido da amostra, reforçam os dados anteriores sobre a segurança do GRP no uso a curto prazo. Apesar de ter ocorrido redução dos escores da escala ABC após uso de GRP, não houve diferença estatística em relação ao placebo. Devido ao desenho crossover e tamanho pequeno da amostra do estudo atual, não foi possível esclarecer a real eficácia do GRP na redução dos sintomas do TEA na infância. Existe a necessidade de novas pesquisas com outros delineamentos e tamanho amostral maior para confirmar a eficácia e segurança do GRP em crianças com autismo. / Introduction: The neuropeptides regulate a variety of aspects of the nervous and neuroendocrine function, acting through activation of specific receptors of the cellular membrane. In system central nervous (CNS) the gastrin-releasing peptide recptors (GRPR) are widely expressed, and numerous central effects have been reported with their activation, including effects on satiety, regulating the circadian rhythm, thermoregulation, stress modulation, response to fear, anxiety and memory. Research has shown that pharmacological blockade of GRPR in animal models leads to the deficits in social interaction, restrictive patterns of behavior and motor stereotypies, autistic symptoms similar to human behavior, suggesting the possibility that the complex GRP/GRPR may have a role in the pathogenesis of autism spectrum disorder (ASD). Recently, two studies are not controlled with the administration of gastrin releasing peptide (GRP) to 13 children with autism suggest that it is safe and can improve some symptoms of the disorder, especially social interaction and symptoms associated with irritability. Objectives: To compare the efficacy, safety, tolerability GRP compared to placebo in ASD symptoms. Methodology: crossover clinical trial, randomized, double-blind, placebo-controlled, using GRP 160 picomol/kg for 4 consecutive days in 10 children with autism. Outcomes were measured by the Aberrant Behavior Checklist scale (ABC). Results: All participants were male, aged between 4 and 9 years. There was a reduction in the scores of the ABC range and its subscales after use GRP and placebo. Despite this reduction be more prominent with the GRP, particularly in subscales Irritability, Stereotypic behavior and Hyperactivity and noncompliance, there was no statistical difference between the results (p 0.334). After a week of infusion, 5 children showed improvement greater than 25% in the total score of the ABC scale in GRP use and 2 with placebo use, however there was no statistical difference (p 0.375). No adverse effects, changes in vital signs or laboratory abnormalities associated with use of GRP in any patient. Conclusions: The results of this study, despite the small sample size, reinforce previous data on the safety of the GRP in the short-term use. Although there was a reduction in ABC scale scores after use of GRP, there was no statistical difference from placebo. Due to the small sample size and design of the current study, it was not possible to clarify the real effectiveness of GRP in reducing the symptoms of ASD in childhood. There is a need for further research with other designs and larger sample size to confirm the efficacy and safety of GRP in children with autism.

Introdução: Os neuropeptídeos regulam uma variedade de aspectos da função nervosa e neuroendócrina, atuando através da ativação de receptores específicos da membrana celular. No sistemana nervoso central (SNC) os receptores do pepetídeo liberador de gastrina (GRPR) são amplamente expressos, e numerosos efeitos centrais têm sido descritos com a sua ativação, incluindo efeitos sobre a saciedade, regulação do ritmo circadiano, termorregulação, modulação do stress, resposta ao medo, ansiedade e memória. Pesquisas mostram que o bloqueio farmacológico do GRPR em modelos animais leva ao aparecimento de deficits na interação social, padrões restritivos de comportamento e estereotipias motoras, sintomas semelhantes ao comportamento autista em humanos, sugerindo a possibilidade de que o complexo GRP/GRPR possa ter um papel na patogênese do transtorno do espectro autista (TEA). Recentemente, dois estudos não controlados com administração do peptídeo liberador de gastrina (GRP) a 13 crianças com autismo sugeriram que ele é seguro e que possa melhorar alguns sintomas do transtorno, principalmente interação social e sintomas associados à irritabilidade. Objetivos: Comparar a eficácia, segurança, tolerabilidade do GRP em relação ao placebo em sintomas do TEA. Metodologia: Ensaio clínico crossover, randomizado, duplo-cego, controlado por placebo, com uso de GRP 160 picomol/kg por 4 dias consecutivos, em 10 crianças com autismo. Os desfechos foram medidos através da escala Aberrant Behavior Checklist (ABC). Resultados: Todos os participantes eram do sexo masculino, com idade entre 4 e 9 anos. Houve uma redução nos escores da escala ABC e suas subescalas após o uso de GRP e de placebo. Apesar dessa redução ser mais proeminente com o GRP, principalmente nas subescalas Irritabilidade, Comportamento estereotipado e Hiperatividade, não houve diferença estatística entre os resultados (p 0,334). Após uma semana da infusão, 5 crianças apresentavam melhora maior que 25% no escore total da escala ABC com uso de GRP e 2 com uso de placebo, não apresentando diferença estatística (p 0,375). Não houve efeitos adversos, alterações dos sinais vitais ou variações laboratoriais associados ao uso de GRP em nenhum paciente. Conclusões: Os resultados deste estudo, apesar do tamanho reduzido da amostra, reforçam os dados anteriores sobre a segurança do GRP no uso a curto prazo. Apesar de ter ocorrido redução dos escores da escala ABC após uso de GRP, não houve diferença estatística em relação ao placebo. Devido ao desenho crossover e tamanho pequeno da amostra do estudo atual, não foi possível esclarecer a real eficácia do GRP na redução dos sintomas do TEA na infância. Existe a necessidade de novas pesquisas com outros delineamentos e tamanho amostral maior para confirmar a eficácia e segurança do GRP em crianças com autismo. / Introduction: The neuropeptides regulate a variety of aspects of the nervous and neuroendocrine function, acting through activation of specific receptors of the cellular membrane. In system central nervous (CNS) the gastrin-releasing peptide recptors (GRPR) are widely expressed, and numerous central effects have been reported with their activation, including effects on satiety, regulating the circadian rhythm, thermoregulation, stress modulation, response to fear, anxiety and memory. Research has shown that pharmacological blockade of GRPR in animal models leads to the deficits in social interaction, restrictive patterns of behavior and motor stereotypies, autistic symptoms similar to human behavior, suggesting the possibility that the complex GRP/GRPR may have a role in the pathogenesis of autism spectrum disorder (ASD). Recently, two studies are not controlled with the administration of gastrin releasing peptide (GRP) to 13 children with autism suggest that it is safe and can improve some symptoms of the disorder, especially social interaction and symptoms associated with irritability. Objectives: To compare the efficacy, safety, tolerability GRP compared to placebo in ASD symptoms. Methodology: crossover clinical trial, randomized, double-blind, placebo-controlled, using GRP 160 picomol/kg for 4 consecutive days in 10 children with autism. Outcomes were measured by the Aberrant Behavior Checklist scale (ABC). Results: All participants were male, aged between 4 and 9 years. There was a reduction in the scores of the ABC range and its subscales after use GRP and placebo. Despite this reduction be more prominent with the GRP, particularly in subscales Irritability, Stereotypic behavior and Hyperactivity and noncompliance, there was no statistical difference between the results (p 0.334). After a week of infusion, 5 children showed improvement greater than 25% in the total score of the ABC scale in GRP use and 2 with placebo use, however there was no statistical difference (p 0.375). No adverse effects, changes in vital signs or laboratory abnormalities associated with use of GRP in any patient. Conclusions: The results of this study, despite the small sample size, reinforce previous data on the safety of the GRP in the short-term use. Although there was a reduction in ABC scale scores after use of GRP, there was no statistical difference from placebo. Due to the small sample size and design of the current study, it was not possible to clarify the real effectiveness of GRP in reducing the symptoms of ASD in childhood. There is a need for further research with other designs and larger sample size to confirm the efficacy and safety of GRP in children with autism.

Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-08-24T17:29:48Z No. of bitstreams: 1 leandrovespolicampos.pdf: 1925979 bytes, checksum: a437d2a7a7488eca8d27ad667669795d (MD5) / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-08-25T11:53:35Z (GMT) No. of bitstreams: 1 leandrovespolicampos.pdf: 1925979 bytes, checksum: a437d2a7a7488eca8d27ad667669795d (MD5) / Made available in DSpace on 2017-08-25T11:53:35Z (GMT). No. of bitstreams: 1 leandrovespolicampos.pdf: 1925979 bytes, checksum: a437d2a7a7488eca8d27ad667669795d (MD5) Previous issue date: 2017-06-26 / FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais / O Hypericum perforatum (HP) é uma espécie utilizada classicamente como um fitoterápico antidepressivo e ansiolítico. Seus diferentes compostos (hipericina e hiperforina) proporcionam muitos outros efeitos, tais como: antinociceptivo e anticonvulsivante. O objetivo desta tese foi investigar a passagem do extrato hidro-alcoólico de H. perforatum pelas barreiras placentária e hematoencefálica fetal e seus prováveis efeitos antinociceptivo, anticonvulsivante, ansiolítico e antidepressivo sobre os descendentes ao atingirem a idade adulta. Para isto, ratas Wistar receberam doses de 36, 72 e 144 mg/kg de HP ao longo de toda a gestação, por via oral. A fluorescência observada demonstrou a presença do extrato de HP em todos os tecidos analisados tanto das ratas gestantes, quanto dos fetos. Testes para avaliação da atividade antinociceptiva e anticonvulsivante do extrato de HP foram realizados em ratas F1 adultas, as quais apresentaram aumento de ambas as respostas. Testes para avaliação das atividades ansiolítica e antidepressiva do extrato de HP foram realizados com ratos F1 adultos, resultando também em aumento desses efeitos. Estes resultados sugerem que a administração de HP durante a gestação provocou mudanças no neurodesenvolvimento de regiões cerebrais relacionadas com o controle da dor, convulsão, ansiedade e depressão em seus descendentes. / Hypericum perforatum (HP) is a classically used species as an antidepressant and anxiolytic herbal remedy. Its different compounds (hypericin and hyperforin) provide many other effects, such as: antinociceptive and anticonvulsive. The objective of this thesis was to investigate the passage of the hydroalcoholic extract of H. perforatum through placental and fetal blood-brain barrier and the probable antinociceptive, anticonvulsive, anxiolytic and antidepressant effects on offspring as they reach adulthood. Wistar rats received oral doses of 36, 72 and 144 mg/kg of HP throughout gestation. The observed fluorescence indicated the presence of the extract in all tissues analyzed from both pregnant rats and fetuses. Tests for evaluation of antinociceptive and anticonvulsant activity of HP extract were performed on adult F1 rats, which showed an increase in both responses. Tests for evaluation of anxiolytic and antidepressant activities of HP extract were performed on adult F1 rats, also resulting in an increase in these effects. These results suggest that the administration of HP during gestation caused changes in the neurodevelopment of brain regions related to the control of pain, seizure, anxiety and depression in their offspring.

The aim of this study was to explore temperament, psychopathology and quality of life (QOL) in adolescents born at extremely low birth weight (ELBW), i.e., < 1000g. ELBW adolescents (N = 15) completed the Revised Cheek and Buss Scale and Mini International Neuropsychiatric Interview 5.0.0 (M.I.N.I.), while their legal guardians completed a biographical questionnaire and the Short Form 12 version 2. The median age of the sample was 13 SD = 2.526 years (60% male) and all participants spoke English. ELBW adolescents with social phobia (n = 6) were more shy (p = .041) and had poorer mental health-related QOL (p = .041) than those without such symptoms. The results suggest that ELBW could be a predisposing factor for increased shyness and psychological disorders including social phobia. Planning of interventions for ELBW individuals should therefore include strategies to prevent or mitigate the effects of these factors in adolescence / Psychology / M. A. (Clinical Psychology)

No description available.

This research explores the need for a unique, self-help manual to provide music students with diagnoses of dyslexia under the umbrella of specific learning disorder (SLD) and/or attention-deficit/hyperactivity disorder (ADHD) a positive way of coping with their musical tendencies. Dyslexia and ADHD are the most prevalent, comorbid neurodevelopmental disorders with symptoms affecting academic, social, and/or personal life. Musical symptoms could include difficulties in any of the following areas: notation reading; time, pulse, and rhythm; posture; fingering coordination; memorization; sight-reading; organization of thoughts, time, and materials; spatial and directional awareness; focused attention; retention of new concepts; positive attitude; and the ability to process written and/or oral information quickly and accurately. This dissertation includes scientific information related to the conditions; an analysis of musical tendencies; pedagogical approaches; personal anecdotal stories that serve to illustrate scientific concepts; and a self-help manual. The manual, "Music, Dyslexia, and ADHD: A Self-Help Manual for Students with Exceptionalities," is a colorful, accessible resource that begins to fill the self-help gap in the musical instruction literature for students with dyslexia and/or ADHD. It offers useful information, multisensory/multimodal techniques, and coping strategies to empower students with these learning differences to achieve more rewarding, independent success throughout their musical studies.

Syftet med min studie är att undersöka vilka möjligheter och utmaningar skogen har som lekmiljö i förskolans verksamhet med ett fokus på vilken potential skogen har för barn med neuropsykiatriska funktionsvariationer (NPF). Studien är gjord utifrån telefonintervjuer med förskolpedagoger. Resultat visar på att skogen har en stor potential för barn med NPF men att det krävs rätt förutsättningar som goda relationer till barnen, kompetens och personalstyrka för att kunna ta vara på skogen som lekmiljö i förskolans verksamhet. Resultat ger även en inblick i det komplexa arbetet att vara pedagog där en del är att ständigt vara problemlösaren. Studiens resultat visar däremot att kunskaper om skogen generellt inte behövs då att vara i natur ger en kroppslig närvaro och ett mer naturligt utforskande hos barnen och pedagogerna. / The purpose of my study is to explore what opportunities and challenges the forest has as a play environment in preschool, with a focus on what potential the forest has for  children with neurodevelopmental disorders. The study is based on telephone interviews with preschool educators. In the result it shows that the forest has great potential for children with neurodevelopmental disorders. But that the right conditions are required, such as good relations with the children, competence and enough staff to be able to take advantage of the forest as a play environment in the preschool. The results also provide an insight into the complex work of being an educator, where parts of it is constantly being the problem solver. The results of the study, on the other hand, show that knowledge about forest is generally not needed because of being in nature provides a physical presence and a more natural way to explore for both the children and educators.

Studiens syfte har varit att undersöka hur studie- och yrkesvägledare, som saknar sakkunskap om neuropsykiatriska funktionsvariationer (NPF), upplever att vägleda elever med dessa diagnoser på gymnasieskolor. Vi har ämnat ta reda på hur studie- och yrkesvägledare bemöter elevernas behov, samt förbereder eleverna inför framtida studie- och yrkesval. De två teoretiska utgångspunkterna för arbetet har varit Self-Determination Theory och den Konstruktivistiska vägledningsteorin. Då studien åsyftar att undersöka studie- och yrkesvägledares upplevelser har vi genomfört kvalitativa semistrukturerade intervjuer med fem studie- och yrkesvägledare. I resultatet framkommer det att respondenterna aktivt arbetar med att anpassa vägledning och förhållningssätt i sitt bemötande av elever med NPF. För att snäva in vårt spektrum något har vi valt att fokusera på de vanligast förekommande diagnoserna, som våra respondenter möter i sitt dagliga arbete; ADHD, autism och dyslexi, De primära verktygen som respondenterna använder sig av är tydlig information, motivation och att hjälpa elever att öka deras självkännedom. Dessa anses vara centrala aspekter när det gäller att förbereda eleverna inför framtida studie- och yrkesval. Slutsatserna som framkommer i studien är att om en studie- och yrkesvägledare ska kunna vägleda elever med NPF är det väsentligt för hen att besitta kunskap om och inneha erforderlig kompetens kring hur NPF påverkar individen. Av lika hög vikt är det att hen vet vilka förutsättningar som råder i samhället gällande studier eller yrken. Vidare har vi också kunnat belysa att vi på vår utbildning inte har fått någon djupare sakkunskap om NPF för att kunna bemöta denna stora grupp elever ute i skolorna. Istället är vi hänvisade till att på egen hand förkovra oss i detta simultant med att vi ska komma ut och vara yrkesverksamma i helt nya arbetssituationer.

Diagnostiseringen av neuropsykiatriska funktionsnedsättningar (NPF) har ökat de senaste åren. Samtidigt visar forskning att barn och unga med NPF löper större risk att drabbas av psykisk ohälsa och utsatthet i samhället. Barn och unga med NPF har ofta komplexa behov och för att de ska få den vård och stöd som de är i behov av kan därför insatser behövas från flera olika håll genom samverkan där främst skola, socialtjänst och hälso- och sjukvården ska vara delaktiga. Dock visar sig stora brister och svårigheter i samverkan mellan dessa aktörer från flera håll vilket resulterar i att dessa barn samt deras familjer riskerar att falla mellan stolarna och inte få sina behov tillgodosedda. Syftet med den här studien har därmed varit att undersöka vilka förutsättningar som anses viktiga för samverkan mellan skola, socialtjänst och barn- och ungdomspsykiatrin gällande barn och unga med NPF samt hur dessa förutsättningar anses hindras inom respektive organisation. En kvalitativ metod med semistrukturerade intervjuer har genomförts med skolkuratorer, socialsekreterare och kurator samt psykolog på barn- och ungdomspsykiatrin. Materialet har analyserats utifrån Danermarks samverkansteori, ett teoretiskt ramverk för olika grader av integration samt nyinstitutionell teori. Resultatet visar att samverkan kring barn och unga med NPF är en viktig faktor för att kunna erbjuda rätt hjälp och stöd. Studiens resultat visar även att samverkan är ett komplext arbetssätt som ofta hindras av otydlig arbetsfördelning och bristande kommunikation. För att samverkan ska fungera krävs det att den efterfrågas och möjliggörs från ledningsnivåer samt att organisatoriska förhållanden tillåter det. En annan viktig förutsättning är att professionellas synsätt, dels om varandra men också kring barn och unga med NPF, synliggörs. Vidare fann studien att föräldrars roll samt diagnosens roll har betydelse för att samverkan kring barn och unga med NPF ska fungera. / The diagnosis of neurodevelopmental disorders has increased in recent years among children and young people. Research shows furthermore that children and young people with neurodevelopmental disorders are at high risk of suffering from mental illness and vulnerability in society. These children and young people often have complex needs and therefore require interventions from several different organizations such as schools, social services and the child and youth psychiatry. To meet these complex needs and in order to provide these people with the best support it is important that schools, social services and the child and youth psychiatry unite and cooperate. However there are major problems and trouble in cooperation between these organizations. This results in many children and young people with neurodevelopmental disorders and their families not getting the help they need. The main aim of this thesis is therefore to investigate conditions and barriers for collaboration between professionals in schools, social services and the child and youth psychiatry in Sweden for the benefit of children and young people with neurodevelopmental disorders. A qualitative method with semi structured interviews has been used to interview school counselors, social secretaries and counselors within the child and youth psychiatry. To analyze the material we used Danermarks collaboration theory and a theoretical framework for different degrees of integration and neo-institutionalist theory. Consensus was reached in this study that collaboration between these organizations is an important factor in being able to offer adequate support and help to children and young people with neurodevelopmental disorders. The result demonstrates that factors enabling collaboration are based on commitment of management levels, good communication and that organizational conditions allow it. Furthermore, the study found that the role of parents and the role of diagnosis are important for collaboration around children and young people with neurodevelopmental disorders to work.