Notre recherche engage une réflexion sur la transmission des techniques du corps (Mauss, 1950, 366) dans un contexte de mondialisation des pratiques sportives. Partant d’un questionnement empirique, nous interrogeons l’enseignement de la natation en Chine, au Sénégal et en France. Nous avons émis l’hypothèse que les représentations considérées comme un élément de l’apprentissage différent culturellement. A Canton, Dakar et Paris, l’étude comparée des contextes culturels (historiques, sportifs et traditionnels) et éducatifs (pédagogiques et didactiques) éclaire notre analyse des représentations des nageurs réalisée au moyen d’un questionnaire. Administré dans les trois villes, son analyse statistique se trouve confortée par les données qualitatives des observations et des entretiens. Nous pouvons conclure que les représentations de l’eau et de l’apprentissage de la natation différent selon les populations étudiées. De ce fait, cette recherche nous invite à considérer le fait de savoir nager dans un processus local de diffusion des techniques du corps incorporant dans sa transmission une part culturelle aux techniques mondialisées / Our study considers body technical transmission (Mauss, 1950, 366) in a context of sport practices globalization. After an initial empirical study of the swimming teaching in China, Senegal and France, we postulated the existence of cultural differences in representations playing a significant role in the training process. In Canton, Dakar and Paris, we established a comparative study of contexts both cultural (historical, sportive and traditional) and educative (pedagogical and didactic). We used a questionnaire as a base to apprehend swimmers representations in the three cities. Its statistical analysis was backed by qualitative data gathered from observations and interviews. We conclude that representations of water and swimming training differ among the studied populations. Therefore, this study calls for considering swimming in a local process of body technical transmission, blending a culture-specific part with globalized techniques

A partir des situations mises en œuvre en éducation physique et sportive (EPS), quels facteurs influencent l’intégration sociale des adolescents présentant une déficience intellectuelle (DI) ? Nos travaux s’appuient sur une expérience d’intégration au collège avec pour objectif d’explorer en profondeur la communication entre deux sous-groupes d’adolescents DI issus d’un Institut médico-éducatif (IME) et trois classes de sixième au cours de séances d’éducation physique et sportive. Pour ce faire, compte tenu des représentations des collégiens analysées à partir d’une enquête par questionnaire et autour d’une étude comportementale au long terme, nous mettons en comparaison un questionnaire sociométrique avec un outil original praxéologique (privilégiant l’ambivalence et l’instabilité). Nous constatons que, malgré des représentations d’ensemble plutôt positives, les résultats de l’intégration sont variés. Certains adolescents DI sont appréciés par les sixièmes tandis que d’autres sont ignorés voire rejetés. Les raisons proviennent à nos yeux, d’une part, de la structure même des sous-groupes d’adolescents DI et de leurs compétences propres. D’autre part, la logique interne de certaines situations motrices semble exclure en grande partie les élèves de l’IME. De ce fait, une meilleure connaissance de ces personnes et des relations qu’elles développent entre elles devraient améliorer leur intégration. De plus, une maîtrise par l’enseignant des effets des situations sociopraxiques mises en œuvre, lors des séances communes aux deux populations, sera probablement bénéfique. / From the situations operated in physical education (PE), what factors determines the social intégration of the teenagers presenting an intellectual deficiency (ID)? Our works lean on an experiment of integration to the middle school with for objective to explore in depth the communication between two subgroups of teenager ID coming from a Medical educational institute and three first classes of the secondary school during physical educational sessions. To do it, considering the representations of the schoolchildren analyzed from a survey by questionnaire and around a behavioral study in the long term, we compare a sociometric questionnaire with an original motor tool (favoring the ambivalence and the instability). The results show that in spite of representations of group rather positive, we notice the effect of a multivariated integration. Certain teenagers DI are appreciated by the sixth of the secondary school whereas of other one are ignored or rejected. The reason result for us on one hand from the structure of the subgroups of teenagers DI and from their appropriate skills. On the other hand the internal logic of certain motor situations, seems to exclude largely the pupils of the medical educational institute. Therefore, a knowledge of these persons and the relations which they develop between them should improve their integration. Furthermore, a control by the teacher about the effects of the sociomotor situations implemented, during the sessions to both populations, will probably be beneficial.

Cette recherche, consacrée aux quartiers difficiles de la ville de Santiago du Chili, a pour objet d’étudier la vision que des jeunes habitants élaborent de leur espace public. L’étude a nécessité une adaptation psychosociale du concept d’espace public et l’élaboration d’un dispositif de recherche permettant de l’appréhender empiriquement. La recherche avait pour but d’étudier le rôle de la participation, ou de la non participation, aux associations de quartier (culturelles, éducatives, sportives, musicales, religieuses) sur la manière d’envisager l’espace public et se représenter autrui et les relations entre les habitants. Cinq quartiers déshérités de la ville de Santiago du Chili, distincts quant à leur histoire, ont constitué notre terrain d’étude et 45 jeunes habitants de ces quartiers ont été interviewés. La méthodologie combine l’approche qualitative et quantitative. Le corpus des entretiens a été analysé avec le logiciel Alceste. La participation aux associations s’avère être une variable importante dans la manière d’envisager la vie des quartiers et le rôle de différentes institutions qui y interviennent. Les représentations se distinguent selon le type des associations auxquelles ces jeunes prennent part. Cette recherche fournit des éléments pour réfléchir sur la pertinence des interventions en matière de sécurité publique, dont ces quartiers font l’objet de la part des autorités et les potentialités de ces jeunes habitants à modeler les relations quotidiennes et envisager leur avenir. Loin de se limiter à la réalité chilienne, ces questions concernent les phénomènes urbains dans une perspective internationale et constituent des enjeux dans les sociétés contemporaines. / The main purpose of this research, dedicated to the poor areas of the city of Santiago, Chile, is to understand the representation that young people develop of their public space. A psychosocial adaptation of the concept of public space and the construction of an empirical research device were needed. The approach is based on the study of concrete aspects of living in neighbourhoods with a special focus on identity and relational dimensions of the subject.Five poor neighbourhoods of Santiago city, distinct in their history, were chosen as fields of study and 45 young people living in these districts were interviewed. The main independent variable in this analysis was to distinguish whether young people were members of a neighbourhood association (and the kind of association: cultural, educational, sporting, musical, or religious) or whether they did not take part in any association.The methodology combines both qualitative and quantitative approaches. Semi-structured interviews have two parts: an oral description of the neighbourhoods, activities and social relationships with the illustration of remarks through the drawing of a socio-spatial map. In the second part, three scenarios evoking the difficulties of daily life were presented and the young people were asked to think of solutions to these difficulties. The corpus of interviews was analysed using the software Alceste. We were able to study their representations of others, social exchanges and various institutions involved in the life of the districts.The results have shown significant differences in the representations that these young people develop of neighbourhood life, their ability to have an impact on it and their perception of the future, according to the association activities they participate in.This research provides elements to reflect on the relevance of interventions in public safety, the potential of these young people to shape their everyday relationships and the representation of their living places oriented towards the future. Far from being limited to the Chilean reality, these issues concern all the major cities of the world and are issues specific to contemporary society.

Rather than designing focused experiments to test individual hypotheses, scientists now commonly acquire measurements using massively parallel techniques, for post hoc interrogation. The resulting data is both high-dimensional and structured, in that observed variables are grouped and ordered into related subspaces, reflecting both natural physical organization and factorial experimental designs. Such structure encodes critical constraints and clues to interpretation, but typical unsupervised learning methods assume exchangeability and fail to account adequately for the structure of data in a flexible and interpretable way. In this thesis, I develop computational methods for exploratory analysis of structured high-dimensional data, and apply them to study gene expression regulation in Parkinson’s (PD) and Huntington’s diseases (HD). BOMBASTIC (Block-Organized, Model-Based, Tree-Indexed Clustering) is a methodology to cluster and visualize data organized in pre-specified subspaces, by combining independent clusterings of blocks into hierarchies. BOMBASTIC provides a formal specification of the block-clustering problem and a modular implementation that facilitates integration, visualization, and comparison of diverse datasets and rapid exploration of alternative analyses. These tools, along with standard methods, were applied to study gene expression in mouse models of neurodegenerative diseases, in collaboration with Dr. Myriam Heiman and Dr. Robert Fenster. In PD, I analyzed cell-type-specific expression following levodopa treatment to study mechanisms underlying levodopa-induced dyskinesia (LID). I identified likely regulators of the transcriptional changes leading to LID and implicated signaling pathways amenable to pharmacological modulation (Heiman, Heilbut et al, 2014). In HD, I analyzed multiple mouse models (Kuhn, 2007), cell-type specific profiles of medium spiny neurons (Fenster, 2011), and an RNA-Seq dataset profiling multiple tissue types over time and across an mHTT allelic series (CHDI, 2015). I found evidence suggesting that altered activity of the PRC2 complex significantly contributes to the transcriptional dysregulation observed in striatal neurons in HD.

Sendo a Educação uma relação fundamentalmente social, é compreensível que apresente mudanças que acompanham ou tentam acompanhar a dinâmica da sociedade. A Educação é um processo contínuo que não se restringe à instituição escolar: aprendemos com a família, os amigos, a religião, a política e, mais intensamente nos últimos anos, com os meios de informação que temos à disposição. O trabalho que ora apresentamos foi desenvolvido sob esta perspectiva, isto é, a de que a Escola é um momento importante da Educação, mas não o único. Procuramos discutir, a partir de um estudo de caso, outros elementos que devem ser colocados no processo de ensinoaprendizagem. Entre esses elementos, destacamos a importância das representações sociais no ensino de Geografia. Para tanto, escolhemos o tema da crise ambiental como meio para avaliarmos como algumas representações sociais podem se manifestar na escola e como sua compreensão pode contribuir para ajudar ou dificultar o trabalho do professor.As representações sociais manifestam-se através de diferentes formas de linguagem. Identificá-las nos permite descobrir relações de poder que estão presentes numa comunidade e, se quisermos, elaborar uma prática de ensino que as coloque em questão. Compreender a linguagem utilizada entre alunos com diferentes realidades sociais numa determinada comunidade foi o meio que escolhemos para identificar algumas representações sociais. A importância da linguagem no processo de ensinoaprendizagem foi discutida com base na obra inacabada de Vygotsky. A interpretação da linguagem para a identificação das representações sociais foi feita com base em Lefevre, Marx e Mészáros e Rafesttin. A apresentação desse trabalho tem como objetivo relatar o processo que nos levou à formulação de questões, os resultados que obtivemos de nossas investigações e a discussão de alguns resultados que consideramos importantes. / The teaching of Geography is a fundamentally social activity and for this reason subject to the most diverse influences that society can provide. Aggregated to this are other elements in the education of primary and secondary school pupils that transcend the scholastic institution, such as the family, friends, politics, culture and the vehicles of information we have at my disposal today. To investigate how some of these influences are manifested in teaching practice from the point of view of the pupils was one of the objectives of this research. I have sought to identify these different influences through language, taking into account possible power relationships. The concept of social representations was utilized for me to identify some influences that may occur in the Teaching of Geography in an area of ambiental interest. The municipality of Iguape in São Paulo was chosen for my investigations, due to its specific characteristics and the possibilities it offered to explore our theme. For this reason, I opted for the ambiental question, as it represents a theme in which different interests, at times contradictory, may present themselves. So I compared two schools with préuniversity/ sixth form Ensino Médio pupils, with different socioeconomic realities, through the use of compositions on the theme of \"Nature and me in Iguape\". In making this comparison in the light of the ambiental theme, I have shown that the school may be an instrument of the legitimization of certain social representations constructed in the society of which it is a part, being also able to contradict some of its curricular intentions. Another fact noted in making this research was the importance of recognizing the discussion about geographical scale for a teaching practice to be truly more critical.

A presente dissertação tem por objetivo analisar o discurso geográfico contido nas obras literárias de Plínio Salgado e Cassiano Ricardo, destacando suas representações espaciais e construções simbólicas pós Semana de Arte Moderna de 1922. Além disso, objetiva-se compreender como as discussões sobre raça e meio atingiram estes autores e, por consequência, as temáticas das suas obras, onde o espaço representado estaria sob o signo do ordenamento social. O espaço aqui representado é o paulista. O tempo, as décadas de 1920-30. E o grupo social, por sua vez, a intelectualidade conservadora paulista, nas figuras de Plínio Salgado e Cassiano Ricardo. Tendo em vista este tripé metodológico, os trabalhos literários destes autores carregariam um conjunto de signos que vão além das interpretações críticas e estéticas do romance, ensaio ou poesia. Os livros escolhidos para análise do discurso foram Martim Cererê (1928) e a Marcha para oeste (1940) de Cassiano Ricardo; O Estrangeiro (1926) e Geografia Sentimental (1937) de Plínio Salgado. Como direcionamento metodológico utilizamos algumas discussões levantadas por Mikhail Bakhin sobre os signos ideológicos e os enunciados socialmente construídos (a obra literária) na análise das obras. / The present paper aims to analyze the geographical speech contained in the literary works of Plinio Salgado and Cassiano Ricardo, highlighting its spatial representations and symbolic constructions after the Modern Art Week of 1922. Besides, it is aimed to understand how the discussions about race and social environment reached these authors and, consequently, the themes of their works, where the space represented would be under the sign of social order. Space represented here is the State of São Paulo. The time is the 20\'s and 30\'s. And social group, on the other hand, is the conservative intellectuality of São Paulo, being represented by Plínio Salgado and Cassiano Ricardo. In view of this methodological tripod, the literary works of these authors would carry a set of signs that go beyond the critical and aesthetic interpretations of the novel, essay or poetry. The books chosen for the speech analysis were Martim Cererê (1928) and Marcha para oeste (1940) from Cassiano Ricardo; O Estrangeiro (1926) and Geografia Sentimental (1937) from Plinio Salgado. As methodological guidance we used some discussions raised by Mikhail Bahktin about ideological signs and socially constructed statements (the literary work) in the analysis of works.

Seja K um grupo de Lie compacto agindo na esfera unitária S&#8319 por isometrias. Mostramos como uma cota superior para as curvaturas principais de uma órbita dessa ação pode ser usada (mas não é suficiente) para encontrar uma cota inferior para o diâmetro do espaço de órbitas S&#8319/K. Em seguida mostramos que existe uma órbita Kp com curvaturas principais majoradas por 4&#8730 14. / Let K be a compact Lie group acting on the unit sphere S&#8319 by isometries. We show how an upper bound on the principal curvatures of one orbit can be used (but is not sufficient) to obtain a lower bound for the diameter of the orbit space S&#8319/K. Then we show that there is an orbit Kp with principal curvatures bounded from above by 4&#8730 14.

Esta pesquisa se propõe a investigar as representações sociais acerca do termo \"Química Ambiental\" entre estudantes iniciantes (segundo semestre) e depois de quatro anos em andamento nos cursos de Bacharelado em Química Ambiental e Licenciatura em Química do Instituto de Química da Universidade de São Paulo. Adotamos como referencial de investigação a Teoria das Representações Sociais e como metodologia a técnica da associação livre de palavras associada à elaboração de um texto. Os resultados foram analisados através da freqüência e ordem média de evocação das palavras para delinear o núcleo central da representação social, além dos elementos periféricos. Nos textos são identificadas unidades de análise que são utilizadas para construção de mapas cognitivos. A associação das palavras mais evocadas com as leituras dos mapas cognitivos para cada aluno proporcionou a construção de um mapa conceitual representativo da visão sobre \"Química Ambiental\" para cada uma das turmas analisadas. De uma forma geral, os iniciantes tanto da Licenciatura em Química como da Química Ambiental apresentaram uma visão naturalista de meio ambiente e também revelaram uma concepção de Educação Ambiental sobre o ambiente, em que bastaria munir as pessoas com informações e fatos relacionados aos problemas ambientais para resolvê-los. Os estudantes iniciantes de ambos os cursos apresentaram uma concepção preservacionista do meio ambiente, sendo mais enfatizada a necessidade de conscientização das pessoas pelos licenciandos. Por outro lado, os bacharelandos em Química Ambiental fazem bastante menção à pesquisa com vistas ao tratamento da poluição e uma visão de remediação é predominante. A diferença entre as representações sociais verificadas entre os alunos das duas modalidades podem estar relacionadas, em parte, à representação social dos alunos sobre o seu papel enquanto profissionais nos aspectos que envolvem a Química Ambiental. Os alunos concluintes representam a Química Ambiental ainda com idéias preservacionistas. Um aspecto positivo, porém, é o aparecimento da idéia de Química Verde em ambos os grupos. As idéias centrais apresentadas pelos estudantes iniciantes em ambos os cursos incluem poluição, meio ambiente, reciclagem, e preservação. Essas mesmas idéias estavam presentes também no grupo de concluintes, o que significa que poderiam ser consideradas constituintes do núcleo central da representação, e que se mantém durante os cursos. Entretanto, foi possível notar a emergência de um elemento periférico de destaque: a Química Verde, que pode ser considerado representativo do amadurecimento do conhecimento técnico dos alunos ao longo do curso de graduação, podendo ser visto como incorporado ao flexível sistema periférico. / This research aims to investigate social representations of environmental chemistry among chemistry student-teachers and environmental chemistry majors from the Institute of Chemistry at the University of São Paulo. Two groups were considered: students enrolled in the second and in the eighth semesters of their respective courses, in order to investigate changes over time. The Theory of Social Representations was adopted as the theoretical reference for this study. The methodology included the technique of free evocation of words, as well as the writing of a text. Results were analyzed considering the frequency and the word evocation mean order, to define the central core and the peripheral elements of the social representation for each group of students. Analysis units were identified in the texts and were used to construct cognitive maps. The association between the most evocated words and individual cognitive maps resulted in a collective conceptual map for each group. Freshmen students from both investigated majors presented a naturalist view of the environment, and a conception of environmental education that can be described as \"about the environment\", in which it would be enough to provide people with information and facts related to the environment to address environmental problems. A preservationist view of the environment was also dominant in both groups, and the need to enhance awareness of people towards environmental issues is specially emphasized by the student-teachers. On the other hand, environmental chemistry majors lay emphasis on the relation between environmental chemistry and research on pollution treatment, and the remediation view is prevalent. The differences between social representations verified in both groups can be partially related to the roles as regard to environmental chemistry within the different professions. Students in the eighth semesters of their respective courses still present strong influence from a preservationist view of the environment. A positive aspect that can be stressed is the rising of ideas related to Green Chemistry in both groups. Representations of freshmen students show a central core founded upon the ideas of pollution, environment, recycling and preservation. The social representation for the group of advanced students rests on the very same ideas. This means that these ideas can be considered as part of the central core of the representation and are maintained during the courses. However, it was possible to notice the incorporation of the peripheral idea associated to Green Chemistry during the undergraduate courses. This can be considered as a result of a growth on technical knowledge which is incorporated to the flexible peripheral elements of the social representations

Final de milênio: de um lado temos a experiência total de dessacralização da sociedade contemporânea baseada no desenvolvimento humano do intelecto e da ciência, e, de outro, um crescente interesse por esta mesma sacralidade perdida, manifestapelo reinvestimento humano nos símbolos sagrados em busca de uma orientação transcendente. Nesta arena convivem inúmeras imagens e idéias que fornecem o substrato para a formação das representações sociais que habitam o imaginário coletivo einfluenciam o imaginário e as identidades pessoais. Toda sociedade possui representações criadas socialmente que estruturam as atitudes, os valores, os conhecimentos e pautam, em conseqüência, as condutas dos diferentes indivíduos e dos grupossociais em relação a múltiplos fenômenos, entre os quais a saúde e a doença. Estes fenômenos, ao mesmo tempo que possuem uma dimensão social, constituem a mais íntima e individual das realidades, sendo exemplos concretos da ligação entre apercepção individual e o simbolismo social, logo, do processo de produção de representações sociais. As representações sociais são uma forma de conhecimento social, um modo de pensar e de interpreta a realidade cotidiana: atividade mentalutilizada por indivíduos e grupos a fim de fixar sua posição em relação a situações, acontecimentos e comunicações que lhes concernem. Situada no campo do conhecimento social a tarefa desta pesquisa é investigar as representações sociais dossacerdotes supremos do Candomblé Jéje-Nagô(pais e mães de santo) sobre saúde e doença. Buscando compreender como esta religião, através das várias formas pelas quais seus símbolos são vivenciados e continuamente re-significados por indivíduos egrupos, produz elementos para a promoção da saúde e para a prevenção, controle e enfrentamento da doença, inlfuenciando a maneira pela qual doente e comunidade percebem e tratam o problema. A pesquisa possui como meta contribuir para a formação ) e prática dos profissionais de saúde através do estudo do caráter sócio-cultural das representações de saúde e doença / The end of millenium: on one hand we have the experience of total desecration of the contemporary society based on the human development of science and intellect, and, on other hand, an increasing interest in the lost sacredness, expressed bythereinvestment in sacred symbols in the search for a transcendent orientation. Several images and ideas live together in this arena, they provide the substrate for the development of the social representations which inhabit thecollectiveimaginary and influence and the personal identities. Every society has representations which are created socially and that structure the attitudes, the values, the knowledge and consequently rule the behavior of different individualsand socialgroups in relations to various phenomena such as health and illness. These phenomena have a social dimension and at the same time, constitute the most intimate and individual of the realities, being concrete examples of theintellectual linkingbetween the individual perception and the social symbolism, thus of the process of production of the social representations. The social representations are a sort of social knowledge, a way of thinking and interpreting dailyreality: mentalactivity used by individuals and groups in order to establish their position in relation to situations, happenings and communication that are of their concern. Situated at the social knowledge area, the aim of this research is toinvestigate the social representationsof the supreme pirest of Candomblé J6eje-Nagô about health and illness. The searching for the understanding of this religion, through the various ways of which its symbols are experienced and continuouslygiven new meanings by individuals and groups, produces elements for the promotion of health and to the prevention, control and confrontation with the illness, influencing the way which the sick person and the community perceive and treat theproblem. It is the aim of this research to contribute to the development and practice of the professionals who deal with health through the study of thesocial-cultural character of the representations of health and diseases

Este estudo objetiva identificar as principais representações sociais, de gênero, circulantes no contexto da educação infantil, bem como conhecer como se estabelecem as relações de gênero/poder nesse contexto, sob uma perspectiva foucaultiana. Realizou-se pesquisa do tipo etnográfico em uma unidade pública de educação Infantil de ensino pré-escolar (UEI), no Estado do Rio de Janeiro. Observaram-se as relações das crianças e seus pares, bem como as relações das professoras com as crianças, em sala de aula e nos espaços exteriores, nas horas de recreação. Focalizaram-se, sobretudo, os brinquedos e as brincadeiras das crianças nesse contexto, por considerá-los um dos principais meios de socialização, na faixa etária de 0 a 6 anos. Os dados demonstram que o cotidiano do ensino préescolar, através do currículo, das práticas pedagógicas e das relações que se estabelecem entre as crianças, principalmente no seu brincar, produz representações e relações de gênero/poder que podem se constituir em desigualdades e discriminações entre meninas e meninos e interferir no processo de formação das identidades de gênero das crianças. Assinala-se a necessidade de medidas e ações, tanto no plano das políticas públicas, quanto no cotidiano do ensino pré- escolar, no sentido da desconstrução da díade gênero/poder, no âmbito da educação infantil. / The objective of this study is to identify the main social representations of gender, circulating within the early childhood education context, and to know how the relations of gender/power are established in this context, under a foucaultian perspective. An ethnographic research took place in a preschool unit in Rio de Janeiro state area. During the research it had been observed the relationships between the children and their peers, and between children and teachers, inside the classroom and outside during free time. The focus was mainly childrens toys and plays in this context, considering them one of the main forms of socialization in the 0 to 6 age group. The collected data shows that the daily practice of teaching preschool through the preschool curriculum, teaching practices and the relationships that are established between the children, especially in their play, produce representations and relations of gender/ power that can constitute inequalities and discrimination between girls and boys, interfering in the young childs process of building a gender identity. The need of measures and actions, not only through public policies, but also through daily practices in the preschool teaching is pointed out, in the sense of deconstructing the dyad gender/power in the early childhood circuit.