Objetivos: validar versões em português do Short Form Health Survey (SF-36) e do Seattle Angina Questionnaire (SAQ) para avaliação de qualidade de vida em pacientes brasileiros com cardiopatia isquêmica. Métodos: estudo transversal com instrumentos traduzidos e aplicados em dois grupos: em 200 pacientes ambulatoriais com cardiopatia isquêmica estável em dois momentos, com intervalo de 14 dias; e em 50 pacientes antes e 30 dias após a angioplastia. Classe funcional foi avaliada pelo Specific Activity Scale. Testes de correlação intraclasse, Cronbach α e Wilcoxon foram utilizados. Resultados: os participantes dos dois grupos apresentaram características clínicodemográficas semelhantes, sendo a taxa de resposta de 78% e 76% no reteste. Reprodutibilidade dos instrumentos (coeficiente α de Cronbach) variou de 0,70 a 0,90 e 0,62 a 0,79 para os domínios do SF-36 e do SAQ, respectivamente. Estabilidade dos instrumentos em 14 dias (coeficiente de correlação intraclasse) foi >0,68 e >0,49 para os domínios do SF-36 e SAQ. No quesito responsividade, o SF-36 demonstrou melhora nos domínios capacidade funcional (10,5), dor (16,5), vitalidade (13,5), aspecto social (10,1) e saúde mental (9,8); e no SAQ, nos domínios estabilidade (41,1) e freqüência (27,3) da angina e percepção da doença (12,0). Os domínios do SF-36 e do SAQ, exceto um, foram consistentemente relacionados à classe funcional. Conclusão: as versões traduzidas dos instrumentos mostraram desempenho adequado sem diferenças entre si, sugerindo serem reprodutíveis, responsivas e válidas para a avaliação da qualidade de vida em pacientes com cardiopatia isquêmica no Brasil. / Objectives: To validate Portuguese-language versions of the Short Form Health Survey (SF-36) and of the Seattle Angina Questionnaire (SAQ), for the evaluation of quality of life in Brazilian patients with ischemic heart disease. Methods: Cross-sectional study using instruments translated and applied to two groups: 200 outpatients with stable ischemic cardiomyopathy at two points in time- 14-day interval; and 50 patients pre and 30 days post angioplasty. Functional class was evaluated by the Specific Activity Scale. Intra-class correlation, Cronbach’s alpha and Wilcoxon tests were used. Results: The participants in both groups presented similar clinical-demographic characteristics, and the rate of response in the retest was 78% and 76%. Reproducibility of the instruments (Cronbach alpha coefficient) varied from 0.70 to 0.90 and 0.62 to 0.79 for the SF-36 and SAQ domains, respectively. Stability of instruments in 14 days (intraclass correlation coefficient) was ≥0.68 and ≥0.49 for the SF-36 and SAQ domains. For the responsiveness item, SF-36 showed improvement in the domains physical functioning (10.5), bodily pain (16.5), vitality (13.5), social functioning (10.1) and mental health (9.8); and in SAQ in those concerning stability (41.1) and frequency (27.3) of angina and disease perception (12.0). The SF-36 and SAQ domains except one were consistently related to functional class. Conclusion: The translated versions of the instruments showed an adequate performance without differences amongst them, suggesting that they are reproducible, responsive and valid to evaluate quality of life in ischemic heart disease patients in Brazil.

Orientadores: Roberta Cunha Matheus Rodrigues, Wilson Nadruz Junior / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas / Made available in DSpace on 2018-08-11T04:09:34Z (GMT). No. of bitstreams: 1 Palhares_LucianaCampanatti_D.pdf: 1907109 bytes, checksum: d72b4310b06e406eda299edf5d572b62 (MD5) Previous issue date: 2008 / Resumo: Dispnéia é um sintoma freqüente entre pacientes hipertensos e tem impacto negativo sobre a qualidade de vida relacionada à saúde (QVRS). O objetivo deste estudo foi verificar as correlações entre função ventricular esquerda (FVE), dispnéia e QVRS em pacientes hipertensos, sem insuficiência cardíaca. Noventa e oito sujeitos foram avaliados quanto à caracterização clínica, antropometria, pressão arterial, variáveis metabólicas e inflamatórias, Doppler tecidual e ecocardiografia convencional. A QVRS foi mensurada com o ¿Short Form¿ SF-36. Pacientes com dispnéia apresentaram maiores índices de massa corpórea (IMC), níveis mais elevados de proteína-C reativa, menor tempo de escolaridade e escores de QVRS significativamente mais baixos na maioria dos domínios do SF-36, em comparação com aqueles sem dispnéia. Não foram observadas diferenças nos parâmetros funcionais da FVE entre os subgrupos, embora os pacientes com dispnéia tenham apresentado maiores índices de massa e hipertrofia de ventrículo esquerdo (HVE). A análise de correlação parcial, ajustada para idade, sexo e IMC, mostrou correlação positiva entre a FVE sistólica e diastólica e o item de transição de saúde, no grupo sem dispnéia. Por outro lado, pacientes com dispnéia apresentaram correlações positivas e de maior magnitude entre os padrões de FVE sistólica e diastólica e os domínios de QVRS, bem como correlações negativas entre massa VE e diâmetro diastólica final de ventrículo esquerdo e QVRS. Concluindo, os resultados sugerem que dispnéia pode ser um marcador de pior QVRS em hipertensos que não preenchem todos os critérios para o diagnóstico de insuficiência cardíaca e um limiar para o desenvolvimento de relações significativas entre o desempenho da FVE e QVRS nestes pacientes / Abstract: Dyspnea is a frequent symptom in hypertensive patients and negatively impacts on health related quality of life (HRQL). The aim of this report is to verify the correlations between left ventricular (LV) function, dyspnea and HRQL in hypertensive patients without overt heart failure. Ninety eight patients not fulfilling criteria for systolic or diastolic heart failure were evaluated by medical history, anthropometry, blood pressure measurement, dosage of metabolic and inflammatory parameters as well as conventional and tissue Doppler echocardiography. HRQL was assessed by the Short Form SF-36. Patients experiencing dyspnea presented higher body mass index, increased C-Reactive Proteins levels, fewer years of schooling and significant lower scores of HRQL in most of the SF-36 domains in comparison to patients with no breathlessness. No significant differences were observed on LV functional parameters between the subgroups, although dyspnea patients presented increased LV mass index and more LV hypertrophy. Partial correlation analyses adjusted for age, sex and body mass index revealed a direct correlation between systolic and diastolic parameters and the Health Transition Item in the group without dyspnea. Conversely, patients with dyspnea displayed stronger direct relationships between systolic and diastolic function and quality of life domains as well as inverse correlations between LV mass and LV end-diastolic diameter and HRQL. Overall, these results suggest that dyspnea might be a valuable marker of worse quality of life in hypertensive not fulfilling criteria for heart failure and a threshold to the development of significant relationship between LV performance and HRQL in such patients / Doutorado / Ciencias Biomedicas / Doutor em Ciências Médicas

Most studies done on the subject of this mini-dissertation have only focused on the differences in chronological detail and text – searching for the facts behind the different accounts. Much attention has thus been paid to the historicity of the various texts and the way in which the different accounts affect each others credibility. But is this the only research to be done? The contention of this mini-dissertation is that to only look at the different texts surrounding Sennacherib’s third campaign through the eyes of a modern historian is to lose the unique and significant message that the various texts wanted to convey. An event only forms part of the construction of a meaningful whole by the author; thus it can be found in various stories at different places and with varying significance attached to it, without meaning that the account of which it forms a part is neither important nor historical. It only means that the authors of the various ancient accounts wanted to achieve different outcomes with their retelling of the original story. For this reason it is important to be able to enter the world represented in, and the mind of the writer of, the ancient texts – allowing the ideology and intentions of the author to be brought to the fore and the text to speak with its own voice, not that of the modern historian. To achieve this requires knowledge of the different symbols, concepts and the meanings attached to them by the ancient societies – shifting the attention to the texts themselves by looking at the way in which the events were narrated as well as what events were narrated; thus revealing the ultimate meaning and purpose of the various texts. The intention of this mini-dissertation is to study the various texts from the underdeveloped angle discussed above, namely ideology and social values. In doing so it is proposed that a new significance will be revealed for the various texts. Research done on the subject of this mini-dissertation has mostly focused on whether there was a single campaign in 701 BC; or two campaigns, one in 701 and one later; or whether chronological difficulties should be explained as arising from the perspective of an author who wrote much later than the actual events occurred. Most studies have only focused on the differences in chronological detail and text – searching for the facts behind the different accounts. Much attention has thus been paid to the historicity of the various texts and the way in which the different accounts affect each others credibility. But is this the only research to be done? The contention of this mini-dissertation is that to only look at the different texts surrounding Sennacherib’s third campaign through the eyes of a modern historian is to lose the unique and significant message that the various texts wanted to convey. An event only forms part of the construction of a meaningful whole by the author; thus it can be found in various stories at different places and with varying significance attached to it, without meaning that the account of which it forms a part is neither important nor historical. It only means that the authors of the various ancient accounts wanted to achieve different outcomes with their retelling of the original story. For this reason it is important to be able to enter the world represented in, and the mind of the writer of, the ancient texts – allowing the ideology and intentions of the author to be brought to the fore and the text to speak with its own voice, not that of the modern historian. To achieve this requires knowledge of the different symbols, concepts and the meanings attached to them by the ancient societies – shifting the attention to the texts themselves by looking at the way in which the events were narrated as well as what events were narrated; thus revealing the ultimate meaning and purpose of the various texts. The intention of this mini-dissertation is to study the various texts from the underdeveloped angle discussed above, namely ideology and social values. The question as to why the various narratives were written as they were will be the focus of this work, pushing aside the modern paradigm and analytical methods which so often focus on the idiosyncrasies instead of the commonalities. In doing so it is proposed that a new significance will be revealed for the various texts. / Dissertation (MA (Ancient Languages and Cultures))--University of Pretoria, 2006. / Ancient Languages / unrestricted

Star formation occurs when the gas (mostly atomic hydrogen; H I) in a galaxy becomes disturbed, forming regions of high density gas, which then collapses to form stars. In dwarf galaxies it is still uncertain which processes contribute to star formation and how much they contribute to star formation. Blue compact dwarf (BCD) galaxies are low mass, low shear, gas rich galaxies that have high star formation rates when compared to other dwarf galaxies. What triggers the dense burst of star formation in BCDs but not other dwarfs is not well understood. It is often suggested that BCDs may have their starburst triggered by gravitational interactions with other galaxies, dwarf-dwarf galaxy mergers, or consumption of intergalactic gas. However, there are BCDs that appear isolated with respect to other galaxies, making an external disturbance unlikely. Here, I study six apparently isolated BCDs from the LITTLE THINGS1sample in an attempt to understand what has triggered their burst of star formation. LITTLE THINGS is an H I survey of 41 dwarf galaxies. Each galaxy has high angular and velocity resolution H I data from the Very Large Array (VLA) telescope and ancillary stellar data. I use these data to study the detailed morphology and kinematics of each galaxy, looking for signatures of starburst triggers. In addition to the VLA data, I have collected Green Bank Telescope data for the six BCDs. These high sensitivity, low resolution data are used to search the surrounding area of each galaxy for extended emission and possible nearby companion galaxies. The VLA data show evidence that each BCD has likely experienced some form of external disturbance despite their apparent isolation. These external disturbances potentially seen in the sample include: ongoing/advanced dwarf-dwarf mergers, an interaction with an unknown external object, and external gas consumption. The GBT data result in no nearby, separate H I companions at the sensitivity of the data. These data therefore suggest that even though these BCDs appear isolated, they have not been evolving in isolation. It is possible that these external disturbances may have triggered the starbursts that defines them as BCDs. 1Local Irregulars That Trace Luminosity Extremes, The H I Nearby Galaxy Survey; https://science.nrao.edu/science/surveys/littlethings

In 2007, one current and two former sex workers, Amy Lebovitch, Terri-Jean Bedford and Valerie Scott launched a charter challenge, Bedford v Canada, arguing that the prostitution provisions criminalizing bawdy houses (section 210), living on the avails (section 212 (1)(j)) and communicating for the purposes of prostitution (section 213.1 (c)) violated their section 7 rights under the Charter of Rights and Freedoms. Six years later, the Supreme Court of Canada ruled unanimously to strike down all three challenged laws, leaving a one-year period to construct a new regime on prostitution. On December 6, 2014, the Protection of Communities and Exploited Persons Act (PCEPA) came into effect, criminalizing, for the first time, prostitution in Canada and introducing a law that replicates many of the provisions of the previous regime. This thesis uses semi-structured interviews and qualitative analysis to examine the experiences of nine street-based sex workers in Ottawa, paying particular attention to experiences after the introduction of the new law. Drawing on the work of Mead & Blumer’s symbolic interactionism theory and Goffman’s concept of stigma the thesis examines how embedded stereotypes in legislation ‘play out’ in the lives of sex workers. I argue that the interactions of sex workers in Ottawa are conditioned by stereotypical assumptions which in turn lead to their broader discrimination and marginalization. This study concludes by finding that the first objective of PCEPA, to protect those who sell their own sexual services, has not been met; instead, PCEPA has resulted in street-based sex workers in Ottawa assuming more risk, and in turn, facing more danger while on the job.

Diplomová práce je zaměřena na aktuální problematiku vstupu Mezinárodních účetních standardů do českého právního prostředí jak z pohledu účetního tak i daňového. Po úvodu a daňové problematice následuje kapitola, která je věnována obecným rozdílům mezi IFRS a českou účetní legislativou. Mezi hlavní obecné rozdíly patří zejména Koncepční rámec, IAS 1 a IAS 8. Oblastí, která obsahuje zřejmě nejvíce odlišností a zároveň se týká téměř všech účetních jednotek je oblast dlouhodobého majetku, proto je této problematice věnována celá kapitola.

This diploma thesis deals with the issue of impairment tests of long-lived assets in the context of the International financial reporting standards with a particular focus on IAS 36 Impairment of assets. The thesis is divided into several parts which deals with the issue of measurement and recognition of assets and impairment test principles followed by specific procedures of impairment tests of individual long-lived assets as well as cash-generating units and goodwill. There is a continuous comparison with the Czech GAAP and US GAAP as well as analysis of information published in financial statements.

I denna uppsats behandlas förbudsklausuler i aktieägaravtal. Med förbudsklausuler avses en reglering som medför att det inte är tillåtet att överlåta aktier, vilket således inskränker i principen om aktiers fria överlåtelse. Var gränsen går mellan vad som är att anse en tillåten förbudsklausul och inte tillåten förbudsklausul är inte helt klar. I uppsatsen skildras i vilka situationer förbudsklausuler kan tänkas vara lämpliga och vilka omständigheter som påverkar hur en förbudsklausul utformas. För att utreda när en förbudsklausul kan vara lämplig inleds uppsatsen med en redogörelse för vad ett aktieägaravtal i grunden är, vilka som normalt är avtalsparter i aktieägaravtal och vilka allmänna avtalsrättsliga principer det finns att förhålla sig till. I uppsatsen berörs även vilka aktiebolagsrättsliga regler som påverkar utformningen av ett aktieägaravtal. För att utreda uppsatsens frågeställningar används dels doktrin som finns inom ämnet aktieägaravtal, dels empiriskt material i form av intervjuer med jurister och advokater som har praktisk erfarenhet. I och med detta vägs både inställningen som framhålls i doktrin och praktiserande juristers inställning till förbudsklausuler in i bedömningen. Vi utreder även vilka risker som finns med förbudsklausuler och hur riskerna lämpligen bör behandlas för att förbudsklausuler inte ska riskera att jämkas eller ogiltigförklaras vid tillämpning av 36 § lagen (1915:218) om avtal och andra rättshandlingar på förmögenhetsrättens område, nedan kallat AvtL eller avtalslagen, på grund av inskränkning i aktiers fria överlåtelse. För att bedöma var gränsen går samt utreda i vilka situationer det skulle vara möjligt att använda sig av generalklausulen i 36 § AvtL, framställs även en redogörelse av vilka omständigheter domstolarna tar särskild hänsyn till vid tillämpning av generalklausulen. Vilka risker som finns med förbudsklausuler beror delvis på vilken situation som avses och aktieägarnas inbördes relation. Av denna anledning hanteras riskerna med hänsyn till omständigheterna i den enskilda situationen. Slutligen görs en avvägning i vilka situationer det finns anledning att använda sig av förbudsklausuler i aktieägaravtal och vilken omfattning förbuden lämpligen bör ha.

Memoria (licenciado en ciencias jurídicas y sociales) / Evidenciado el escaso tratamiento sobre la responsabilidad civil de los Ministros de Estado, consagrada en los artículos 36 y 53 N°2 de la Constitución, la presente memoria pretende realizar un estudio acabado sobre la materia abordándolo desde lo general a lo particular. Para ello, fue necesario hacer una recopilación doctrinaria y jurisprudencial que permitiera analizar en profundidad cada arista del tema tratado. De esta manera, se analiza el concepto de autoridad pública para, luego, estudiar la figura de los Ministros de Estado en nuestra legislación. A continuación, dado el eje central de la investigación, se abordó la responsabilidad de las autoridades públicas en general y su evolución. Posteriormente, se profundiza en la responsabilidad patrimonial de los Ministros de Estado, sus antecedentes históricos y doctrinarios. Los capítulos finales exponen la aplicación jurisprudencial del instituto, analizando los principales elementos discutidos para, concluir en un estudio detallado sobre los artículos que lo regulan (características, requisitos y procedimiento) y el esclarecimiento de su naturaleza jurídica. Mediante los apartados señalados, este trabajo pretende concluir la pertinencia actual de la responsabilidad civil de los Ministros de Estado y su coherencia con la regulación vigente.

In Deutschland ist eine zunehmende Kinderlosigkeit zu beklagen (Statistisches Bundesamt 2009). Die Ursachen hierfür werden primär vor dem Hintergrund der Unvereinbarkeit von Berufstätigkeit und Mutterschaft diskutiert (Schrupp 2008). Aus lerntheoretischer Perspektive wären subjektiv empfundene gesundheitliche Ein-schränkungen von Frauen nach der Geburt eines Kindes als weitere Ursache denkbar. Über die subjektiven Gesundheitseinschätzungen von Frauen im geburtshilflichen Kontext ist jedoch nur wenig bekannt. Vereinzelt finden sich Hinweise, dass Frauen ihre subjektive Gesundheit (SGH) nach der Geburt ihres Kindes trotz bestehender Morbidität sehr positiv bewerten (Bauer 2011, Schytt et al. 2005, Borrmann 2005). Ziel der Studie ist es die subjektive Morbidität, die SGH sowie die gesundheitsbezogenen Lebensqualität (GHLQ) gesunder Frauen acht Wochen und sechs Monate nach der Geburt eines Kindes zu erfassen und die Faktoren zu ermitteln, die sich beeinflussend auf SGH und GHLQ auswirken. Methode: Retrospektive, longitudinale Kohortenstudie. Basis der Sekundäranalyse bilden Daten von 1029 Erst- und Mehrgebärenden, die im Rahmen einer multizentrisch angelegten, prospektiven Interventionsstudie zum Versorgungskonzept Hebammenkreißsaal an der Hochschule Osnabrück unter Förderung des Bundesministeri-ums für Bildung und Forschung (FKZ 01 GT 0616) zum Zeitpunkt der Geburt (t0) sowie acht Wochen (t1) und sechs Monate (t2) nach der Geburt erhoben wurden. Zur Ermittlung der SGH wurde der SF-1 angewendet. Die Operationalisierung der GHLQ erfolgte über die standardisierte körperliche und die standardisierte psychische Summenskala des SF-36. Ergebnisse: Gut die Hälfte der Studienteilnehmerinnen bewertete ihre SGH zu t1 und t2 besser als gut, wobei Erstgebärende gegenüber Mehrgebärenden signifikant häufiger diese positive Einschätzung vornahmen (p<.007). Neben einer Reihe von Faktoren, die in keinem unmittelbaren Zusammenhang mit der Geburt stehen, zeigten sich geburtsspezifische Aspekte als signifikante Einflussgrößen. In der Gruppe der Erstgebärenden er-höhte sich bei Vorliegen geburtsverletzungsbedingter Beschwerden die Chance auf eine beeinträchtigte SGH zu t1 signifikant (OR 1.68, [95% KI 1.04-2.71]; p=.035). In der Gruppe der Mehrgebärenden erwies sich ein nega-tives Geburtserleben zu t2 als signifikante Einflussgröße für eine beeinträchtigte SGH (OR 7.66, [95% KI 2.17-26.99]; p=.002). Hinsichtlich der GHLQ konnten ebenfalls geburtsspezifische Aspekte als Einflussgrößen ermit-telt werden. Zu t1 erhöhten in der Gruppe der Erstgebärenden geburtsverletzungsbedingte Beschwerden die Chance auf eine verminderte GHLQ um fast das Dreifache (OR 2.83, [95% KI 1.63-4.93]; p<.001). Ein negati-ves Geburtserleben verdoppelte die Chance auf eine verminderte GHLQ in dieser Gruppe (OR 2.09, [95% KI 1.19-3.65]; p=.010). In der Gruppe der Mehrgebärenden zeigte sich das negative Geburtserleben ebenfalls als signifikante Einflussgröße (OR 3.93, [95% KI 1.14-13.53]; p=.030). Dies allerdings erst zu t2. Insgesamt konn-ten in einzelnen Subskalen des SF-36 signifikante Abweichungen zwischen der landes-, alters- und geschlechts-spezifischen Normstichprobe und dem Studiensample festgestellt werden. Schlussfolgerung: Geburtsverletzungsbedingte Beschwerden und ein negatives Geburtserleben beeinflussen die SGH und GHLQ nachhaltig. Mit dem Anspruch einer qualitativ hochwertigen geburtshilflichen Versorgung gilt es die subjektiven Gesundheitseinschätzungen von Frauen nach der Geburt eines Kindes standardisiert zu evalu-ieren. Um Ceiling-effekte zu vermeiden müssen die in anderen Bereichen bisher üblichen Erhebungsverfahren für den geburtshilflichen Kontext modifiziert werden