Submitted by Alex Sandro R?go (alex@ifpb.edu.br) on 2016-11-23T14:05:28Z No. of bitstreams: 1 CARACTERIZA??O DA COBERTURA DE SINAIS NA FAIXA DE 700 MHZ EM AMBIENTES INTERNOS CONSIDERANDO OS EFEITOS DA POLARIZA??O E DO AZIMUTE DA ANTENA DIRETIVA.pdf: 3166825 bytes, checksum: 661cc825c83146a571ccfe6ff55de464 (MD5) / Approved for entry into archive by Alex Sandro R?go (alex@ifpb.edu.br) on 2016-11-23T14:06:22Z (GMT) No. of bitstreams: 1 CARACTERIZA??O DA COBERTURA DE SINAIS NA FAIXA DE 700 MHZ EM AMBIENTES INTERNOS CONSIDERANDO OS EFEITOS DA POLARIZA??O E DO AZIMUTE DA ANTENA DIRETIVA.pdf: 3166825 bytes, checksum: 661cc825c83146a571ccfe6ff55de464 (MD5) / Made available in DSpace on 2016-11-23T14:06:22Z (GMT). No. of bitstreams: 1 CARACTERIZA??O DA COBERTURA DE SINAIS NA FAIXA DE 700 MHZ EM AMBIENTES INTERNOS CONSIDERANDO OS EFEITOS DA POLARIZA??O E DO AZIMUTE DA ANTENA DIRETIVA.pdf: 3166825 bytes, checksum: 661cc825c83146a571ccfe6ff55de464 (MD5) Previous issue date: 2015-07 / Com o aparecimento dos sistemas de comunica??o pessoal, tornou-se importante a caracteriza??o da propaga??o em ambientes fechados. A atenua??o no espa?o livre, a propaga??o por multipercurso e as intera??es que a onda mant?m com obst?culos s?o fen?menos mais relevantes associados ? propaga??o em ambientes interiores. Entretanto, se o canal indoor for bem caracterizado os efeitos das perdas de propaga??o eletromagn?ticas podem ser minimizadas, atrav?s da varia??o angular da antena do transmissor, a fim de encontrar a posi??o adequada para a localiza??o do transmissor. No contexto de uma rede sem fio, um ambiente interno difere de um ambiente externo em dois aspectos: menor raio de cobertura e maior variabilidade no ambiente. Constata-se, na pr?tica, que a propaga??o dentro de edifica??es ? influenciada por aspectos espec?ficos, tais como sua arquitetura e pelos materiais usados na constru??o. Nas ?ltimas d?cadas foram desenvolvidos e aperfei?oados v?rios modelos de predi??o que consideram as caracter?sticas do ambiente interno. O presente trabalho tem por objetivo estabelecer a caracteriza??o da cobertura de sinais de comunica??o sem fio em ambientes interiores na faixa de frequ?ncia em torno de 700 MHz. Essa banda foi escolhida devido a sua destina??o para ser utilizada pelos sistemas de comunica??o em banda larga 4G/LTE no Brasil. Os resultados simulados foram obtidos utilizando o programa comercial WinProp?, com base no m?todo do Tra?ado de Raios. Durante as simula??es foi proposto um m?todo simplificado de predi??o de cobertura, onde foram considerados transmissores virtuais, posicionados pr?ximos ?s paredes de in?cio de cada corredor transversal (situa??o sem visada entre transmissor e receptor), que consideraram como pot?ncias de sa?das as mesmas pot?ncias aferidas naqueles pontos ou locais, a partir do transmissor real. As campanhas de medi??es para a caracteriza??o experimental da cobertura de sinal foram realizadas, obtendo-se valores m?dios do sinal em intervalos regularmente espa?ados, de modo a se garantir uma menor influ?ncia do fen?meno de desvanecimento r?pido e uma maior espacialidade entre elas. Deste modo, os resultados obtidos mostraram uma boa concord?ncia entre os valores simulados, medidos e te?ricos, calculados a partir da f?rmula de Friis, nas situa??es com visada e sem visada direta.

Transparency is a business approach which has become more and more popular for fashion companies to apply in recent years. The purpose of transparency is to publish internal company information for stakeholders. Most often, the information is about how companies act socially, environmentally and economically. This study investigates consumer attitudes towards fashion companies that have chosen to apply transparency in their business practices. In order to explicate previous research, the study also examines how consumers want this information assigned along with what specific information consumers’ request. The study’s empirical data is based on nine qualitative interviews conducted with female consumers of different ages.The result of the study shows that consumers in general have no deeper knowledge or awareness of transparency or corporate social responsibility. This unconsciousness proved to have a major impact on the consumer's behavior, attitude and preferences towards transparency. Even though all respondents have a positive attitude towards the idea of transparency, there is some skepticism about the concept. The intentions of applying transparency and the content that is being conveyed are questioned. Respondents believe that the content can easily be manipulated in order to make companies appear better than they actually are. However, this skepticism can be reduced if an external party can control and review the company's transparency.This study also shows that consumers are happy to see that companies publish and convey internal information. The information should be brief, straightforward and easy to understand. It should be assigned to the consumers, instead of asking the consumers to search for it themselves. Perceptions of how the information should be conveyed differ greatly among respondents depending on age and amount of prior knowledge. Therefore it is crucial for companies to adapt the content and pick an appropriate platform for their customers. By understanding the target group's preferences, companies can more easily find a starting point in their work with corporate social responsibility and more effectively to convey it to stakeholders. However, there is a need to raise general awareness of the industry's problems. A way to do this is by discussing the subject in broader channels. This study is written in Swedish. / Transparens är ett arbetssätt som på senare år har blivit mer och mer populärt för klädföretag att applicera. Syftet med transparens är att kunna offentliggöra intern företagsinformation för intressenter. Oftast handlar informationen om hur företag agerar socialt, miljömässigt och ekonomiskt. Denna studie undersöker konsumenters attityder till klädföretag som väljer att applicera transparens i sin verksamhet. För att utveckla tidigare forskningen undersöks även hur konsumenter vill tilldelas denna information och vad för specifik information som efterfrågas. Studiens empiri bygger på nio stycken kvalitativa intervjuer som hållits med kvinnliga konsumenter i olika åldrar.Resultatet i denna studie visar att konsumenter överlag inte har någon djupare kunskap eller medvetenhet om transparens och företags arbete med deras sociala och miljömässiga ansvar. Denna omedvetenhet visade sig ha en stor påverkan på konsumentens beteende, attityd och preferenser till transparens. Även om samtliga respondenter är positivt inställda till idén av transparens finns en skepsis till konceptet. Avsikterna med att applicera transparens och vad som förmedlas ifrågasätts. Respondenter anser att innehållet lätt kan förskönas i syfte att få företag att framstå som bättre än vad de egentligen är. Denna skepsis anses dock kunna minska om en extern part kan kontrollera och granska företags transparens.Denna studie redogör även att konsumenter gärna ser att företag offentliggör och förmedlar intern information. Formatet ska då gärna vara kortfattat och lättförstått, informationen ska tilldelas konsumenten istället för att konsumenten själv ska behöva leta upp den. Hur detta ska förmedlas skiljer sig mycket åt mellan respondenterna beroende på ålder och mängd förkunskap. Därför är det särskilt viktigt för företag att utgå från den specifika målgruppen för att kunna välja ett passande format att förmedla via den mest lämpliga plattformen. Genom att förstå sin målgrupps preferenser kan företag lättare finna en utgångspunkt i sitt arbete med samhällsansvar och mer effektivt förmedla detta till intressenter. Dock finns det ett behov av att lyfta branschens problematik utanför företagen och öka konsumenters medvetenhet genom att diskutera ämnet i bredare kanaler

Transparency is a business approach which has become more and more popular for fashion companies to apply in recent years. The purpose of transparency is to publish internal company information for stakeholders. Most often, the information is about how companies act socially, environmentally and economically. This study investigates consumer attitudes towards fashion companies that have chosen to apply transparency in their business practices. In order to explicate previous research, the study also examines how consumers want this information assigned along with what specific information consumers’ request. The study’s empirical data is based on nine qualitative interviews conducted with female consumers of different ages. The result of the study shows that consumers in general have no deeper knowledge or awareness of transparency or corporate social responsibility. This unconsciousness proved to have a major impact on the consumer's behavior, attitude and preferences towards transparency. Even though all respondents have a positive attitude towards the idea of transparency, there is some skepticism about the concept. The intentions of applying transparency and the content that is being conveyed are questioned. Respondents believe that the content can easily be manipulated in order to make companies appear better than they actually are. However, this skepticism can be reduced if an external party can control and review the company's transparency. This study also shows that consumers are happy to see that companies publish and convey internal information. The information should be brief, straightforward and easy to understand. It should be assigned to the consumers, instead of asking the consumers to search for it themselves. Perceptions of how the information should be conveyed differ greatly among respondents depending on age and amount of prior knowledge. Therefore it is crucial for companies to adapt the content and pick an appropriate platform for their customers. By understanding the target group's preferences, companies can more easily find a starting point in their work with corporate social responsibility and more effectively to convey it to stakeholders. However, there is a need to raise general awareness of the industry's problems. A way to do this is by discussing the subject in broader channels. This study is written in Swedish. / Transparens är ett arbetssätt som på senare år har blivit mer och mer populärt för klädföretag att applicera. Syftet med transparens är att kunna offentliggöra intern företagsinformation för intressenter. Oftast handlar informationen om hur företag agerar socialt, miljömässigt och ekonomiskt. Denna studie undersöker konsumenters attityder till klädföretag som väljer att applicera transparens i sin verksamhet. För att utveckla tidigare forskningen undersöks även hur konsumenter vill tilldelas denna information och vad för specifik information som efterfrågas. Studiens empiri bygger på nio stycken kvalitativa intervjuer som hållits med kvinnliga konsumenter i olika åldrar. Resultatet i denna studie visar att konsumenter överlag inte har någon djupare kunskap eller medvetenhet om transparens och företags arbete med deras sociala och miljömässiga ansvar. Denna omedvetenhet visade sig ha en stor påverkan på konsumentens beteende, attityd och preferenser till transparens. Även om samtliga respondenter är positivt inställda till idén av transparens finns en skepsis till konceptet. Avsikterna med att applicera transparens och vad som förmedlas ifrågasätts. Respondenter anser att innehållet lätt kan förskönas i syfte att få företag att framstå som bättre än vad de egentligen är. Denna skepsis anses dock kunna minska om en extern part kan kontrollera och granska företags transparens. Denna studie redogör även att konsumenter gärna ser att företag offentliggör och förmedlar intern information. Formatet ska då gärna vara kortfattat och lättförstått, informationen ska tilldelas konsumenten istället för att konsumenten själv ska behöva leta upp den. Hur detta ska förmedlas skiljer sig mycket åt mellan respondenterna beroende på ålder och mängd förkunskap. Därför är det särskilt viktigt för företag att utgå från den specifika målgruppen för att kunna välja ett passande format att förmedla via den mest lämpliga plattformen. Genom att förstå sin målgrupps preferenser kan företag lättare finna en utgångspunkt i sitt arbete med samhällsansvar och mer effektivt förmedla detta till intressenter. Dock finns det ett behov av att lyfta branschens problematik utanför företagen och öka konsumenters medvetenhet genom att diskutera ämnet i bredare kanaler.

Bakgrund: Forskning inom socialt arbete indikerar att omvårdnadspersonal inom arbetet med äldre människor kan agera i strid med vårdtagares rätt till autonomi i situationer då en potentiell risk för skada uppstår. Syfte: Studiens syften var att: a) undersöka omvårdnadspersonalens förhållningssätt till autonomifrämjande och riskaverta omvårdnadssituationer och b) att använda Theory of Reasoned Action (TRA) för att undersöka vilka faktorer som påverkar personalens intentioner till agerande i dessa situationer. Metod: Studien nyttjade en kvantitativ tvärsnitts- och kvasi-experimentell design, med vinjettbaserade enkäter skildrandes tre omvårdnadssituationer som skiljer sig i autonomifrämjande och riskaverta ageranden hos omvårdnadspersonalen. Urval: Urvalet bestod av omvårdnadspersonal (n=62) från fem vård- och omsorgsboenden för personer med demens. Resultat: Sammantaget tyder omvårdnadspersonalens bedömningar av situationerna att riskaverta ageranden var vanligare än autonomifrämjande ageranden både hos dem själva och bland deras kollegor. Genom analyser av TRA ges belägg för att de subjektiva normerna påverkar personalens intentioner till agerande mer än attityder. / Background: Research within social work indicates that staff working in care for older people can act in a way that conflicts with the care-recipient’s right to autonomy in situations where there is a risk of harm. Purpose: The study’s aims were a) to investigate staff’s response to autonomy-promoting and risk-averse care situations and b) to use the Theory of Reasoned Action (TRA) to investigate which factors influence staff’s intentions to act in these situations. Method: A quantitative cross-sectional quasi-experimental design, with vignette-based surveys depicting three care situations differing in terms of autonomy-promoting or risk-averse staff behavior. Sample: Nursing staff (N = 62) recruited from five specialist dementia care homes. Results: Overall, staff ratings of the vignettes suggested risk-aversion is more common than autonomy-promotion, both among their colleagues and in their own behavior, while the TRA analyses indicated that subjective norms more than attitudes influence the behavioral intentions of staff.

Bakgrund: Forskning om missförhållanden visar att äldre som bor på särskilda boenden utsätts för olika former av missförhållanden. De olika formerna av missförhållanden som sker inom äldreomsorgen kommer till uttryck på olika sätt, såsom psykisk och fysisk vanvård samt försummelse. Syfte: Syftet med studien var att undersöka hur omvårdnadspersonal uppfattar eventuella missförhållanden inom äldreomsorgen och varför de tror att missförhållanden uppstår på särskilda boenden. Syftet var även att utifrån Theory of Reasoned Action tolka omvårdnadspersonalens potentiella agerande i situationer då det uppstår missförhållanden. Metod: Studien nyttjade en kvalitativ forskningsmetod i form av en vinjettstudie medfokusgrupper. Materialet analyserades genom tematisk analys. Resultat: Resultatet visade att omvårdnadspersonalen hade olika uppfattningar kring missförhållanden. Brist i arbetsmiljö såsom tidsbrist, personalbrist och stress var troliga orsaker till missförhållanden. Genom Theory of Reasoned Action indikerades att kollegors påverkan, så kallade ”subjektiva normer” och egna attityder kan bidra till en förståelse om varför missförhållanden uppstår på särskilda boenden. / Background: Research on elder abuse shows that elderly people living in nursing homes are exposed to various forms of abuse. The various forms of abuse that occur in elderly care are expressed in different ways, such as mental and physical abuse, and neglect. Aim: The aim of the study was to investigate how nursing staff perceive possible elder abuse in elderly care and why they believe that elder abuse occurs in nursing homes. The aim was also to interpret the nursing staff's potential actions in situations where elder abuse occurs based on the Theory of Reasoned Action. Method: The study used a vignette methodology with four focus group interviews. The material was analysed through thematic analysis. Results: The results showed that nursing staff had different perceptions of elder abuse. The respondents believed that, among other things, deficiencies in the work environment such as lack of time, staff shortages and stress were likely reasons for elder abuse. The Theory of Reasoned Action indicated that colleagues' influence, also known as "subjective norms" and their own attitudes can contribute to an understanding of why elder abuse occurs in nursing home.

O Glioblastoma é um dos tumores mais agressivos do sistema nervoso central e entre as diversas neoplasias possui um dos piores prognósticos. Mesmo com as novas estratégias de tratamento, a sobrevida de pacientes portadores de glioblastoma continua sendo muito baixa, sendo a temozolomida (TMZ) o agente mais comum usado no seu tratamento. O ácido tetra-o-metil nordihidroguaiarético (M4N), é um novo agente terapêutico que funciona como um repressor transcricional global de genes dependentes do fator de transcrição Sp1, tais como Survivina e Cdk1. No presente estudo, foram investigados os níveis de expressão do gene Survivina, suas variantes gênicas por splicing alternativo e Cdk1 em amostras tumorais e linhagens celulares de GBM. Adicionalmente, foram investigados os efeitos do M4N em combinação ou não com TMZ e/ou radiação em culturas primárias e linhagens celulares de GBM. Ensaios de qRT-PCR foram realizados para determiner a expressão de mRNA das variantes gênicas de Survivina e Cdk1. A proliferação celular foi analisada pelo ensaio XTT e os niveis de apoptose e variações do ciclo celular foram determinados por citometría de fluxo. Analises de combinação de drogas utilizando diferentes estratégias de administração (simultânea e seqüencial) foram realizados baseados no método de Chou-Talalay em linhagens celulares e culturas primárias de GBM. Para os ensaios de sobrevivência clonogênica, foram utilizadas as doses de 2, 4 e 6 Gy de radiação gamma. Todas as variantes por splicing alternativo de Survivina e o gene Cdk1 foram expressos em amostras (n=16) e linhagens celulares (n=6) de GBM, exceto a variante Survivina-2B que apenas foi expressa nas linhagens celulares de GBM. O tratamento com M4N diminuiu a expressão de Cdk1, Survivina e a variante Survivina-Ex3, enquanto que houve um aumento da expressão da variante Survivina-2B. O M4N diminuiu a proliferação celular de forma isolada e sinérgicamente quando combinada com TMZ. Além disso, o M4N aumentou os efeitos da radiação, principalmente quando associado com TMZ. O M4N causou morte celular apoptótica, diminuição do índice mitótico e parada do ciclo celular principalmente na fase x G2/M. Os resultados do presente estudo sugerem a potencial aplicação clínica de M4N em combinação com TMZ e radiação no tratamento do GBM. / Glioblastoma (GBM), one of the most human malignant neoplasia, responds poorly to current treatment modalities, being temozolomide (TMZ) the most used drug in its treatment. TetraO-methyl Nordihydroguaiaretic Acid (M4N) is a global transcriptional repressor of genes dependents of Sp1 transcription factor, such as Survivin and Cdk1. In this study was evaluated the gene expression of Survivin, their spliced-variants and Cdk1 in GBM samples and cell lines. Moreover, it was investigated the effects of M4N combined or not with TMZ and/or radiation on primary cultures and cell lines of GBM. qRT-PCR assays were performed to determine the Survivin-spliced variants and Cdk1 gene mRNA expression in GBM tumor samples and cell lines. Cell proliferation was measured by XTT assay and cell cycle and apoptosis were determined by flow cytometry. Drug combination analyzes using different schedules of administration (simultaneous and sequential) were performed based in ChouTalalay method on GBM cell lines and primary cultures. For clonogenic survival, it was used the doses of 2, 4, and 6 Gy of gamma radiation. All Survivin-spliced variants and Cdk1 gene were expressed in GBM samples (n=16) and cell lines (n=6), except the Survivin-2B variant that was only expressed in GBM cell lines. M4N treatment down regulated the expression of Cdk1, Survivin and Survivin-Ex3 variant, while the Survivin-2B variant was up-regulated. M4N decreased the cell proliferation separately and synergistically with TMZ, moreover it enhanced the radiation effects, mainly when associated with TMZ. M4N also induced apoptotic cell death, decreased mitotic index and arrested the cell cycle mainly in G2/M phase. Our results suggest a potential clinical application of M4N in combination with TMZ and radiation in GB treatment.

Submitted by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-06-30T18:25:54Z No. of bitstreams: 1 DIS_LIVIA_NORA_BRANDALISE_PARCIAL.pdf: 6570989 bytes, checksum: b62ad256dd548bf41239e556f8d77cc1 (MD5) / Approved for entry into archive by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-06-30T18:26:01Z (GMT) No. of bitstreams: 1 DIS_LIVIA_NORA_BRANDALISE_PARCIAL.pdf: 6570989 bytes, checksum: b62ad256dd548bf41239e556f8d77cc1 (MD5) / Made available in DSpace on 2017-06-30T18:26:08Z (GMT). No. of bitstreams: 1 DIS_LIVIA_NORA_BRANDALISE_PARCIAL.pdf: 6570989 bytes, checksum: b62ad256dd548bf41239e556f8d77cc1 (MD5) Previous issue date: 2017-03-20 / Background: Personality traits are an important construct in the study of obesity, both to understand its influence on this condition?s origins and to evaluate its role in responses to treatments, such as bariatric surgery. The main models used so far, are based on dimensions of normal personality traits, bringing conflicting results. Hence, there is a demand for instruments that can give more accuracy and improve the study of the personality in this population capturing more dysfunctional traits. In a special section for emerging measures, the new edition of the Diagnostic Statistical Manual of Psychiatric Disorders (DSM-5) proposed an instrument to measure personality mal-adaptive traits: the Personality Inventory for DSM-5 (PID-5), whose psychometric properties have been tested in several samples and localities. Despite promising results, PID-5 has not yet been evaluated psychometrically in other clinical populations where the "personality" construct can have an important impact (in etiologic and prognostic ways), such as obese candidates for bariatric surgery. Objective: The aim of this study is to investigate the psychometric properties of the PID-5 in the evaluation of pathological personality traits in obese candidates for bariatric surgery. This constitutes a fundamental step to assess whether the instrument keeps its original technical features allowing its use and correct interpretation in this population. Setting: Centro da Obesidade e S?ndrome Metab?lica, Pontif?cia Universidade Cat?lica do Rio Grande do Sul (COM-PUCRS), Porto Alegre, Brazil Methods: Cross-sectional study involving 312 medical records of patients who applied for bariatric surgery. We collected demographic data and scores from instruments applied in the psychiatric evaluation routine. The reliability of facets and domains was evaluated through internal consistency indices and the unidimensionality of facets was verified through factorial methods. Exploratory Structural Equations Modeling was performed to test the higher order structure of the model. To investigate convergent validity, linear correlations were calculated between PID-5 scales and instrument scores of correlated constructs (depression, anxiety, defensive styles, and quality of life). Given the characteristic of the sample, we also correlated PID-5 with body mass index (BMI) and binge eating symptoms. Data was analyzed by Factor and Mplus softwares. Results: Facets were unidimensional, with the exception of Risk Taking, better explained by two factors. We replicate the higher order structure of 5 factors of the original model, with good congruence coefficients. The internal consistency of the domains was satisfactory, however, some facets showed fragility of internal consistency, mainly when calculated with more robust methods. In general, the domains and facets correlated as expected with correlated constructs. Conclusion: This study found evidences of adequate psychometric properties of PID-5 for a sample of obese candidates for bariatric surgery. Our results indicate that the instrument is appropriate to be applied in this population, consistently evaluating personality domains and facets of the DSM-5 model. More studies in other centers are needed to replicate and reinforce our findings. / Introdu??o: Tra?os de personalidade s?o um construto importante no estudo da obesidade, tanto para entender sua influ?ncia na g?nese desta condi??o, quanto para avaliar o papel que desempenham nas respostas aos tratamentos, como a cirurgia bari?trica. At? o momento, os principais instrumentos utilizados para o estudo desta rela??o baseiam-se em modelos que avaliam dimens?es de tra?os normais da personalidade, trazendo resultados conflitantes. Existe portanto, uma demanda por instrumentos que possam fornecer maior acur?cia e aperfei?oar o estudo da personalidade nesta popula??o, captando tra?os mais disfuncionais. Em uma se??o especial para medidas emergentes, a nova edi??o do Manual Estat?stico Diagn?stico dos Transtornos Psiqui?tricos (DSM-5) prop?s um instrumento para mensurar tra?os mal-adaptativos de personalidade: o Personality Inventory for DSM-5 (PID-5), cujas propriedades psicom?tricas vem sendo testadas em diversas amostras e localidades. A despeito de promissores resultados, o PID-5 ainda n?o foi avaliado psicometricamente em outras popula??es cl?nicas onde o construto ?personalidade? pode ter um impacto importante (em termos etiol?gicos e progn?sticos), como a constitu?da por obesos candidatos a cirurgia bari?trica. Objetivo: Investigar as propriedades psicom?tricas do PID-5 na avalia??o dos tra?os patol?gicos de personalidade em pacientes obesos candidatos a cirurgia bari?trica. Esta ? uma etapa metodol?gica fundamental para verificar se o instrumento mant?m suas caracter?sticas t?cnicas originais viabilizando seu uso e correta interpreta??o nesta popula??o. Local: Centro da Obesidade e S?ndrome Metab?lica, Pontif?cia Universidade Cat?lica do Rio Grande do Sul (COM-PUCRS), Porto Alegre, Brasil M?todos: Estudo transversal envolvendo 312 prontu?rios de pacientes candidatos a cirurgia bari?trica. Foram coletados dados demogr?ficos e escores de instrumentos aplicados na rotina de avalia??o psiqui?trica pr?-operat?ria. A fidedignidade das facetas e dom?nios do PID-5 foi avaliada atrav?s de ?ndices de consist?ncia interna e a unidimensionalidade das facetas atrav?s de m?todos fatoriais. O teste da estrutura de ordem superior foi realizado por meio do Modelagem de Equa??es Estruturais Explorat?rias. Para investigar a validade convergente, foram calculadas correla??es lineares entre as escalas do PID-5 e os escores de instrumentos de construtos correlatos (depress?o, ansiedade, estilos defensivos e qualidade de vida). Dada a caracter?stica da amostra, tamb?m correlacionamos o instrumento com o ?ndice de massa corporal (IMC) e sintomas compulsivos alimentares. Os dados foram analisados pelos softwares Factor e Mplus. Resultados: As facetas de personalidade apresentaram-se de forma unidimensional, ? ?nica exce??o de Exposi??o a Riscos, melhor explicada por dois fatores. Replicamos a estrutura de ordem superior de 5 fatores do modelo original, com bons coeficientes de congru?ncia. A consist?ncia interna dos dom?nios foi satisfat?ria, entretanto algumas facetas demonstraram fragilidades de consist?ncia interna, sobretudo calculados com m?todos mais robustos. De forma geral, os dom?nios e facetas correlacionaram-se de forma esperada com os construtos correlatos. Conclus?o: Este estudo encontrou evid?ncias de propriedades psicom?tricas adequadas do PID-5 para uma amostra de obesos graves candidatos a cirurgia bari?trica. Nossos resultados indicam que o instrumento ? apropriado para ser aplicado nesta popula??o, avaliando coerentemente os dom?nios e facetas da personalidade do modelo DSM-5. Mais estudos em outros centros s?o necess?rios para replicar e refor?ar nossos achado.

Submitted by Jadson Francisco de Jesus SILVA (jadson@uefs.br) on 2017-02-15T01:08:04Z No. of bitstreams: 1 Disserta??o DANIEL DA SILVA DE JESUS - PDF.pdf: 3083183 bytes, checksum: bd6b14e2cc2a38ab54b674866d480292 (MD5) / Made available in DSpace on 2017-02-15T01:08:04Z (GMT). No. of bitstreams: 1 Disserta??o DANIEL DA SILVA DE JESUS - PDF.pdf: 3083183 bytes, checksum: bd6b14e2cc2a38ab54b674866d480292 (MD5) Previous issue date: 2016-04-29 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Lamiaceae species have been widely studied due to their antioxidant, antimicrobial and antiviral properties. There is scientific interest in developing technologies for the enhancement of production systems of medicinal plants, given that the low concentration of bioactive compounds is a major obstacle to their economic exploitation. Works with some species have shown that traces metals such as Cd, Cu and Zn, act as abiotic elicitors, directly influencing in the production of bioactive substances. Martianthus leucocephalus (Mart. Ex Benth.) J.F.B. Pastore produces rich essential oil in isobornyl formate with high antimicrobial activity. This work aimed to evaluate the effect of Cd, Cu and Zn stress, on the species through growth, minerals accumulation, essential oil content and its major components, phenolic content and antioxidant enzymes. Furthermore, the phytoremediation potential of this species was observed in the presence of the tested metals. When applied in high concentrations all metals caused sharp reduction in the M. leucocephalus growth, however, was observed that Zn stress caused an increase in the content of volatile compounds. Plant exposure of to milder metals concentrations caused less growth reduction and nutritional unbalance M. leucocephalus. In this case, Cd stress stimulate higher production of volatile compounds. No metal treatment alters the essential oils quality. Cd, Cu and Zn was accumulated in higher concentration in the roots, demonstrating the potential of this species to phytostabilization in contaminated environments. The Cd stress caused an increase in total phenolics concentration, while the peroxidases activity and lipid peroxidation was higher in metals stressed plants. / Esp?cies da fam?lia Lamiaceae t?m sido amplamente estudadas, devido as suas propriedades antioxidantes, antimicrobianas e antivirais. Existe interesse cientifico no desenvolvimento de tecnologias para a potencializa??o de sistemas de produ??o das plantas medicinais, tendo em vista que a baixa concentra??o dos compostos bioativos representa um dos maiores obst?culos para a sua explora??o econ?mica. Trabalhos com algumas esp?cies t?m demonstrado que os metais tra?os, como o Cd, Cu e Zn, atuam como eliciadores abi?ticos, influenciando de forma direta na produ??o de subst?ncias bioativas. Martianthus leucocephalus (Mart. ex Benth.) J.F.B. Pastore ? uma esp?cie que produz ?leo essencial rico em formiato de isobornila, com elevada atividade antimicrobiana. Neste trabalho objetivou-se avaliar o efeito do estresse por Cd, Cu e Zn, sobre a esp?cie, quantificando-se o crescimento, ac?mulo de minerais nas diversas partes da planta, teor de ?leo essencial e de seus componentes majorit?rios, teor de compostos fen?licos e de enzimas antioxidantes. Al?m disso, foi verificado o potencial fitorremediador desta esp?cie, na presen?a dos metais testados. Quando aplicados em elevadas concentra??es todos os metais provocaram forte redu??o no crescimento de M. leucocephalus, entretanto, nestas condi??es apenas o Zn provocou incremento no teor dos compostos vol?teis. A exposi??o das plantas desta esp?cie a concentra??es mais amenas dos metais provocou menor redu??o no crescimento e desbalan?o nutricional de M. leucocephalus. Neste caso, apenas o Cd estimulou maior produ??o de compostos vol?teis, mas nenhum tratamento com metal alterou a qualidade dos ?leos essenciais obtidos. As plantas acumularam Cd, Cu e Zn em maior concentra??o nas ra?zes, demonstrando o potencial da esp?cie para a fitoestabiliza??o desses metais em ambientes contaminados. O estresse por Cd provocou aumento da concentra??o de fen?licos totais, enquanto que a atividade das peroxidases e a peroxida??o lip?dica foi maior nas plantas submetidas aos tr?s metais.

Made available in DSpace on 2015-04-14T13:34:27Z (GMT). No. of bitstreams: 1 399860.pdf: 1071121 bytes, checksum: 40567b188bd088b00b2d90f816a8343b (MD5) Previous issue date: 2007-11-27 / Podemos considerar a resili?ncia como parte do processo evolutivo. O ser humano se v? submetido inevitavelmente, ao longo de seu desenvolvimento, a adversidades frente ?s quais colocar? em jogo sua possibilidade de se recuperar e seguir adiante perseguindo metas. E uma das tentativas propensa a significar adversidade ?, sem d?vida, o envelhecimento. Diante disso, este estudo apresentou como objetivo estudar as rela??es da resili?ncia no idoso com as fun??es cognitivas e as vari?veis s?cio-demogr?ficas: g?nero, idade,escolaridade e renda. Al?m disso, relacionou os escores obtidos por meio da Escala de Resili?ncia (ER) com os escores de outros dois instrumentos: Percep??o Subjetiva de Queixas de Mem?ria e Mini-Exame do Estado Mental (MEEM). A amostra foi constitu?da por 86 idosos, sendo 67 do sexo feminino e 19 do sexo masculino, com idade variando entre 60 e 90 anos. Inicialmente, os dados quantitativos foram descritos por m?dia e desvio padr?o. As vari?veis categ?ricas foram apresentadas atrav?s de contagens e percentuais. A compara??o do escore de resili?ncia foi realizada com teste t de Student no caso de dois grupos. Para comparar m?dias de tr?s ou mais grupos foi utilizada a An?lise de Vari?ncia (ANOVA) One-Way. O n?vel de signific?ncia adotado foi de =0,05. Os resultados revelaram que n?o houve rela??o entre resili?ncia e as vari?veis demogr?ficas. Demonstraram, entretanto, que um n?mero mais elevado de queixas subjetivas de mem?ria correspondia a baixos ?ndices de resili?ncia. Tamb?m revelou haver uma correla??o direta e significativa entre a Escala de Resili?ncia e o Mini-Exame do Estado Mental. Desse modo, conclui-se que quanto mais altos os escores de resili?ncia, maiores os escores no desempenho cognitivo entre os idosos.

Submitted by Setor de Tratamento da Informa??o - BC/PUCRS (tede2@pucrs.br) on 2016-05-19T12:41:10Z No. of bitstreams: 1 DIS_ALEXANDRE_ANTONIO_MARQUES_COELHO_COMPLETO.pdf: 1873139 bytes, checksum: c32a6b63bb7f49213c1a5b16f0ae1ead (MD5) / Made available in DSpace on 2016-05-19T12:41:10Z (GMT). No. of bitstreams: 1 DIS_ALEXANDRE_ANTONIO_MARQUES_COELHO_COMPLETO.pdf: 1873139 bytes, checksum: c32a6b63bb7f49213c1a5b16f0ae1ead (MD5) Previous issue date: 2015-11-12 / Adolescent pregnancy and abortion are frequent causes of health problems and death. We studied women 18 to 60 years old selected from the Brazilian Internet Study on Temperament and Psychopathology, a web-based survey in which participants provided details on abortion and pregnancy history, and completed the Affective and Emotional Temperament Composite (AFECT) Scale. A total of 53833 women comprised the sample, from which 11.4% of the participants had induced at least one abortion and 3.9% have had a child before the age of 18. Depressive, Cyclothymic, Irritable, Hyperthymic and Euphoric types were associated with a 25%-64% higher chance of having a child before completing 18 years old when compared to Euthymics. Except for the avoidant type, all affective types were associated with the chance to have provoked an abortion, particularly Euphoric (OR=1.83), Volatile (OR = 1.65) and Cyclothymic (OR=1.54). Volition was the only dimensional trait associated with the age of the first child. In contrast, a history of abortion was associated with higher scores for Anger and Desire and lower scores for Caution, Coping and Control. Women who have abortions had prominent externalizing traits, suggesting a reduced ?moral constraint?, whereas adolescent pregnancy was weakly associated with temperament traits. / Gravidez na adolesc?ncia e aborto s?o frequentes causas de doen?as e morte entre as mulheres. Mulheres de 18 a 60 anos foram selecionadas do Brazilian Internet Study on Temperament and Psychopathology (BRAINSTEP), uma pesquisa atrav?s da internet na qual as participantes responderam quest?es relacionadas ? hist?ria de gesta??es e aborto, e completaram a escala Affective and Emotional Composite Temperament (AFECT). Foram selecionadas 53833 mulheres, das quais 11,4% haviam induzido pelo menos um aborto, e 3,9% haviam tido um filho antes dos 18 anos. Os tipos Depressivo, Ciclot?mico, Irrit?vel, Hipert?mico e Euf?rico foram associados com uma chance 25-64% maior de ter um filho antes dos 18 anos em compara??o com os Eut?micos. Com a exce??o do tipo Evitativo, todos os tipos afetivos foram associados com a chance de ter provocado um aborto, particularmente o Euf?rico (OR=1,83), Vol?til (OR = 1,65) e Ciclot?mico (OR = 1,54). Vontade foi o ?nico tra?o dimensional associado ? idade ao nascimento do primeiro filho. Por outro lado, quanto maior o n?mero de abortos, maiores os escores de Raiva e Desejo, e menores os escores de Cautela, Maturidade e Controle. As mulheres que cometeram abortos apresentaram proeminentes tra?os de externaliza??o, o que sugere reduzidas restri??es morais, enquanto o nascimento de filhos na adolesc?ncia foi fracamente associado com os tra?os de temperamento.