No description available.

No description available.

The claim to successfully have eliminated racism and xenophobia in socialist Germany was crucial for the GDR’s demarcation against the Federal Republic and for GDR’s political self-conception. According to the state party SED, both the GDR’s government and its people met with all members of the working class, regardless their ethnicity or culture, in the spirit of Völkerfreundschaft – the peoples’ friendship. In the early 1960s, suffering from a lack of work power, the GDR began to recruit foreign workers, and continued to do so up until German reunification. When workers arrived from Eastern Europe, Latin America, Africa and Asia, the propositions of antiracism and peoples’ friendship were tested in practice. Following a discourse-analytical approach this study analyzes how the ideal of Völkerfreundschaft was dealt with and how it was exploited and altered both by citizens communicating with the state and within party-loyal circles. It examines when, why and by whom ethnicity was downplayed in favor of common class affiliation, and under which circumstances it regained importance. While latest research on foreigners in the GDR has focused on diagnosing the discrepancy between ideological claims and reality this study goes beyond such an approach and analyzes how this discrepancy was dealt with – both by state authorities, the state-owned factories and ordinary people – in everyday life.   This study is a contribution to migration research, as well as to everyday-life-history and history of mentality in the GDR.

No description available.

The claim to successfully have eliminated racism and xenophobia in socialist Germany was crucial for the GDR’s demarcation against the Federal Republic and for GDR’s political self-conception. According to the state party SED, both the GDR’s government and its people met with all members of the working class, regardless their ethnicity or culture, in the spirit of Völkerfreundschaft – the peoples’ friendship. In the early 1960s, suffering from a lack of work power, the GDR began to recruit foreign workers, and continued to do so up until German reunification. When workers arrived from Eastern Europe, Latin America, Africa and Asia, the propositions of antiracism and peoples’ friendship were tested in practice. Following a discourse-analytical approach this study analyzes how the ideal of Völkerfreundschaft was reproduced, exploited and altered both by citizens communicating with the state and within party-loyal circles. It examines when, why and by whom ethnicity was downplayed in favor of common class affiliation, and under which circumstances it regained importance. While latest research on foreigners in the GDR has focused on diagnosing the discrepancy between ideological claims and reality this study goes beyond such an approach and analyzes how this discrepancy was dealt with – both by state authorities, the state-owned factories and ordinary people – in everyday life.   This study is a contribution to migration research, as well as to everyday-life-history and history of mentality in the GDR.

La greffe de cellules souches hématopoïétiques (CSH) constitue une avancée thérapeutique considérable dans le traitement de maladies hématologiques et non hématologiques. Toutefois, malgré qu’elle sauve des vies, elle n’est pas sans risque. Le syndrome lymphoprolifératif post-transplantation (SLPT) est l’une des complications qui peut survenir après ce type de greffe avec un risque de mortalité pouvant atteindre 80% en l’absence de traitement. Par ailleurs, les traitements disponibles pour limiter le développement de ce syndrome ne sont pas sans effets néfastes. Le SLPT est surtout une conséquence d’une primo-infection ou d’une réactivation non-contrôlée du virus d’Epstein-Barr (VEB). Au moins 90% des adultes sont porteurs du VEB alors que ce pourcentage est d’environ 50-70% chez les enfants. Il est important de bien comprendre les facteurs de risque de l’infection active du VEB et du SLPT pour une meilleure gestion des greffés. Cette thèse a pour objectif de contribuer aux connaissances quant aux déterminants du VEB et du SLPT chez les greffés pédiatriques de CSH. Dans un premier temps, une revue systématique combinée à une méta-analyse a été réalisée pour élaborer un portrait exhaustif des facteurs de risque connus du VEB et du SLPT chez les greffés adultes et pédiatriques de CSH. Ensuite, à l’aide d’une étude de cohorte prospective multicentrique canadienne qui a enrôlé 156 patients pédiatriques greffés de CSH, le lien entre la transfusion de produits sanguins et l’infection VEB post-greffe a été analysé. Finalement, l’étude de cohorte multicentrique a aussi permis d’explorer des nouveaux facteurs de risque des évènements liés au VEB allant de l’ADNémie VEB à la suspicion du SLPT. Les résultats de la revue systématique et de la méta-analyse ont montré que l’utilisation de la globuline antithymocyte (ATG) pour prévenir la maladie du greffon contre l’hôte est le principal facteur impliqué dans la survenue post-greffe des infections actives du VEB et du SLPT. La forte hétérogénéité entre les études a limité la comparaison des résultats et très peu d’études portaient exclusivement sur les patients pédiatriques. D’autre part, l’analyse statistique au sein de la cohorte multicentrique n’a pas révélé une augmentation statistiquement significative du risque d’infection du VEB post-greffe associé à la transfusion. Toutefois, une analyse de génotypage du virus a indiqué que la transfusion serait très probablement liée à la primo-infection VEB d’un patient séronégatif, et ce malgré la leucoréduction (qui élimine virtuellement la présence des virus associés aux composantes cellulaires des produits sanguins). Par ailleurs, nos analyses dans la cohorte multicentrique ont corroboré l’association entre l’ATG et les évènements liés au VEB post-greffe et mis en relief deux nouvelles associations. Le mycophénolate mofétil, un médicament utilisé pour prévenir la maladie du greffon contre l’hôte, limiterait le risque des évènements liés au VEB par son action antiproliférative des lymphocytes T et B (incluant ceux infectés par le VEB), tandis que les filles seraient plus à risque des formes relativement sévères de l’infection du VEB post-greffe que les garçons. Le rationnel autour de cette dernière association n’est pas connu. Des nouvelles recherches permettront d’apprécier la reproductibilité de ces résultats. / Hematopoietic stem cell transplantation (HSC) constitutes a notable therapeutic advance in the treatment of hematological and non-hematological diseases. However, despite saving lives, it is not without risk. Post-transplant lymphoproliferative disease (PTLD) is one of the complications that can occur after this type of transplant with a mortality risk of up to 80% if left untreated. Moreover, the treatments available to limit the development of this disease are not without harmful effects on transplant recipients. PTLD is predominantly a consequence of primary infection or uncontrolled reactivation of Epstein-Barr virus (EBV). At least 90% of adults are carriers of EBV, compared to around 50-70% in the pediatric population. It is important to understand the risk factors for active EBV infection and PLTD in order to better manage transplant recipients. This thesis aims to contribute to knowledge on the determinants of active EBV infection and PTLD in pediatric HSC transplant recipients. A systematic review combined with a meta-analysis was carried out to develop a comprehensive portrait of the known risk factors for EBV and PTLD in adult and pediatric HSC transplant recipients. Then, using a Canadian multicenter prospective cohort study that enrolled 156 pediatric HSC transplant patients, the link between blood product transfusion and post-transplant EBV infection was analyzed. Finally, the multicenter cohort study also explored new risk factors for EBV-related events ranging from EBV DNAemia to suspicion of PTLD. The results of the systematic review and the meta-analysis revealed that the use of anti-thymocyte globulin (ATG) to prevent graft-versus-host disease is the main factor implicated in the post-transplant occurrence of active EBV infection and PTLD. The high heterogeneity between studies limited the comparison of results and very few studies focused exclusively on pediatric patients. On the other hand, statistical analysis within the multicenter cohort did not reveal a significant increase in the risk of post-transplant EBV infection associated with transfusion. However, genotyping analysis of viral strains from blood donors of an EBV-negative patient who received an EBV-negative graft indicated that one of the blood donors was the source of the primary EBV infection in the patient, despite leukoreduction (which virtually eliminates the presence of cell-associated viruses in blood products). Furthermore, our analyses in the multicenter cohort corroborated the association between ATG and post-transplant EBV-related events, and highlighted two new associations. First, mycophenolate mofetil, a drug used to prevent graft-versus-host disease, is believed to reduce the risk of EBV-related events through its antiproliferative action on T and B lymphocytes (including EBV-infected B cells). Second, girls are more at risk of relatively severe forms of post-transplant EBV infection than boys. The rationale behind this latter association is unknown. New research will make it possible to assess the reproducibility of these results.

:Einleitung S. 85 Internationale Industriekooperation als Marktoffensive S. 86 Montageproduktion auf Manufakturniveau S. 88 Technologietransfer und Finanzjonglage S. 92 Industriekooperation als Fehlinvestition S. 97 Zusammenfassung S. 99

No description available.

In 1950, the leader of the German Democratic Republic (East Germany), Walter Ulbricht, began a policy of connecting foreign threats with domestic policy failures as if the two were the same, and as if he was not responsible for either. This absolved him of blame for those failures and allowed Ulbricht to define his internal enemies as agents of the western powers. He used the state's secret police force, known as the Stasi, to provide the information that supported his claims of western obstructionism and to intimidate his adversaries. This resulted in a politicization of intelligence whereby Stasi officers slanted information so that it conformed to Ulbricht's doctrine of western interference. Comparisons made of eyewitness' statements to the morale reports filed by Stasi agents show that there was a difference between how the East German worker felt and the way the Stasi portrayed their attitudes to the politburo. Consequently, prior to June 17, 1953, when labor strikes inspired a million East German citizens to rise up against Ulbricht's oppressive government, the politicization of Stasi intelligence caused information over labor unrest to be unreliable at a time of increasing risk to the regime. This study shows the extent of Ulbricht's politicization of Stasi intelligence and its effect on the June 1953 uprising in the German Democratic Republic.

Dieser Artikel wurde zur Richtigstellung der bisher selbst in Fachkreisen verbreiteten Falschaussagen oder Unklarheiten erarbeitet, die immer wieder zu Aussagen führen, dass die weltberühmten Automobilkarosserien der Marke „Gläser Karosserie Dresden“ in ihrem Ursprung der Karosserieentwicklung auf den Dresdner Sattler und Kutschenbauer Carl Heinrich Gläser (1831-1903) zurückzuführen sind. Dem ist nicht so, denn Heinrich Gläser hat nie eine Automobilkarosse gebaut, sondern hochwertige Kutschen, und war ein absoluter Gegner dieser seit 1886 einsetzenden Motorisierungs-Entwicklung. Er bezeichnete die Automobile als „Stinkekutschen“, und für seinen jungen Mitinhaber in der Dresdner Firma, den Wagenfabrikanten Emil Heuer (1857 - 1934) aus Radeberg, wurde erst nach Gläsers Tod 1903 der Weg frei, um mit dem Automobil-Karosseriebau zu beginnen. Es erscheint immer wieder als ein Phänomen, dass der Name des Mannes, der einzigartige Automobilkarosserien als weltweit bewunderte Unikate unter der Marke „Gläser“ erschuf, unter seinem eigenen Namen „Emil Heuer“ so gut wie unbekannt ist. Oldtimer-Fans kennen und bewundern die „Gläser“-Karosserien, die in Wahrheit in Emil Heuers Firma entworfen und gefertigt worden sind, einer der damals angesehensten Karosseriebaufirmen Deutschlands. Emil Heuer wurde bereits Anfang des 20. Jahrhunderts als Karosseriebauer, unter der Marke „Gläser“, mit zu einem der gefragtesten Karosseuren für die Fahrzeugproduzenten der Automobilherstellung. Seine Erfolgsgeschichte ist beeindruckend und zeigt seinen Werdegang auf, vom Hufschmied und Wagenbauer zum Konstrukteur von 'Radeberger-Bierkutschwagen mit Petroleumheizung' bis zum Unternehmer mit der Fertigung von einzigartigen Cabriolet-Karosserien von Weltruf. Die angefügte vollständige Chronologie beginnt mit der Gründung 1864 durch den Dresdner Wagenbauer Heinrich Gläser und belegt die gesamte Unternehmensentwicklung der Marke 'Gläser Karosserie' unter Emil Heuer bis zum Erlöschen der Marke 1951/52. Viele bisher veröffentlichte Fehl-Informationen werden anhand von Primärquellen richtiggestellt. Das umfangreiche Verzeichnis der Quellen und Anmerkungen belegt die Daten und Fakten im Artikel.