Fast and accurate diagnosis is always in demand by modern medical professionals and in the area of national defense. At present, limitations of testing speed, sample conditions, and levels of precision exist under current technologies, which are usually slow and involve testing the specimen under laboratory conditions. Typically, these methods also involve several biochemical processing steps and subsequent detection of low energy luminescence or electrical changes, all of which reduce the speed of the test as well as limit the precision. In order to solve these problems and improve the sensing performance, this project proposes an innovative CMOS magnetic biological sensor system for rapidly testing the presence of potential pathogens and bioterrorism agents (zoonotic microorganisms) both in specimens and especially in the environment. The sensor uses an electromagnetic detection mechanism to measure changes in the number of microorganisms--tagged by iron nanoparticles--that are placed on the surface of an integrated circuit (IC) chip. Measured magnetic effects are transformed into electronic signals that count the number and type of organisms present. This biosensor introduces a novel design of a conical-shaped inductor, which achieves ultra-accuracy of sensing biological pathogens. The whole system is integrated on a single chip based on the fabrication process of IBM 180 nm (CMOS_IBM_7RF), which makes the sensor small-sized, portable, high speed, and low cost. The results of designing, simulating, and fabricating the sensor are reported in this dissertation. / Ph. D.

Advances in wireless technology have recently led to the potential for higher data rates and greater functionality. Wireless home and business networks and 3G and 4G cellular phone systems are promising technologies striving for market acceptance, requiring low-cost, low-power, and compact solutions. One approach to meet these demands is system-on-a-chip (SoC) integration, where RF/analog and digital circuitry reside on the same chip, creating a mixed-signal environment. Concurrently, there is tremendous incentive to utilize Si-based technologies to leverage existing fabrication and design infrastructure and the corresponding economies of scale. While the SoC approach is attractive, it presents major challenges for circuit designers, particularly in the design of monolithic voltage controlled oscillators (VCOs). VCOs are important components in the up or downconversion of RF signals in wireless transceivers. VCOs must have very low phase noise and spurious emissions, and be extremely power efficient to meet system requirements. To meet these specifications, VCOs require high-quality factor (Q) tank circuits and reduction of noise from active devices; however, the lack of high-quality monolithic inductors, along with low noise transistors in traditional Si technologies, has been a limiting factor. This thesis presents the design, characterization, and comparison of three monolithic 3-4 GHz VCOs and an integrated 5-6 GHz VCO with tunable polyphase outputs. Each VCO is designed around a differential -G_{M} core with an LC tank circuit. The circuits exploit two Si-based device technologies: Silicon Germanium (SiGe) Heterojunction Bipolar Transistors (HBTs) for a cross-coupled collectors circuit and Graded-Channel MOS (GC-MOS) transistors for a complementary (CMOS) implementation. The circuits were fabricated using the Motorola 0.4 μm CDR1 SiGe BiCMOS process, which consists of four interconnected metal layers and a thick copper (10 μm) metal bump layer for improved inductive components. The VCO implementations are targeted to meet the stringent phase noise specifications for the GSM/EGSM 3G cellular standard. The specifications state that the VCO output cannot exceed -162 dBc/Hz sideband noise at 20 MHz offset from the carrier. Simultaneously, oscillators must be designed to address other system level effects, such as feed-through of the local oscillator (LO). LO feed-through directly results in self-mixing in direct conversion receivers, which gives rise to unwanted corrupting DC offsets. Therefore, a system-level strategy is employed to avoid such issues. For example, multiplying the oscillator frequency by two or four times can help avoid self-mixing during downconversion by moving the LO out of the bandwidth of the RF front-end. Meanwhile, direct conversion or low-IF (intermediate frequency) receiver architectures utilize in-phase and quadrature (I/Q) downconversion signal recovery and image rejection. Any imbalance between the I and Q channels can result in an increase in bit-error-rate (BER) and/or decrease in the image rejection ratio (IRR). To compensate for such an imbalance, an integrated tunable polyphase filter is implemented with a VCO. Control voltages between the differential I and Q channels can be individually controlled to help compensate for I/Q mismatches. This thesis includes an introduction to design flow and layout strategies for oscillator implementations. A detailed comparison of the advantages and disadvantages of the SiGe HBTs and GC-MOS device in 3-4 GHz VCOs is presented. In addition, an overview of full-wave electromagnetic characterization of differential dual inductors is given. The oscillators are characterized for tuning range, output power, and phase noise. Finally, new measurement techniques for the 5-6 GHz VCO with a tunable polyphase filter are explored. A comparison between the time and frequency approaches is also offered. / Master of Science

Rail à rail entrée - sortie, classe AB, faible consommation sont autant de critères que le concepteur d'amplificateur opérationnel (AOP) intègre pour réaliser une cellule analogique performante. Pour un AOP standard, l'accent n'est pas porté sur une caractéristique particulière mais sur l’ensemble de celle-ci. Dans le but d'augmenter le nombre de fonction par circuit intégré, la tension d'alimentation des AOPs ainsi que leur consommation en courant tendent à diminuer. L'objectif des circuits réalisés est de doubler le facteur de mérite des circuits déjà présents dans le portefeuille de STMicroelectronics. Le facteur de mérite est un indice qui compare des circuits équivalents. Il est défini par le rapport entre le produit capacité de charge x produit gain bande-passante et le produit courant de consommation x tension d'alimentation. L'état de l'art des structures d'AOPs a orienté l'étude vers des structures analogiques possédant au moins trois étages de gain. Un niveau de gain statique supérieur à la centaine de décibel est nécessaire pour utiliser ces amplificateurs dans des systèmes contre-réactionnés. Puisque chaque étage de gain introduit un noeud haute impédance et que chaque noeud haute impédance est à l'origine d'un pôle, l'étude de la compensation fréquentielle s'est avérée indispensable pour obtenir des structures optimisées. Pour simplifier l'étude de ces AOPs, le développement d'outils d'aide à la conception analogique a contribué à l'automatisation de plusieurs tâches.. Ces différents travaux ont été ponctués par la réalisation et la caractérisation de six circuits. Les compensations fréquentielles utilisées dans ces circuits sont la compensation nested miller , la compensation reversed nested miller et la compensation multipath nested miller . Parmi les six circuits, une moitié a été réalisée uniquement dans le but de valider des concepts de compensation fréquentielle et l'autre moitié avec toutes les contraintes d'une documentation technique propre à la famille d'AOP standard. / To be in line with the standard of operational amplifier (opamp), designer integrates in his circuit several functionalities like a Rail to rail input and output, class AB output stage and low power consumption. For standard products, there is no outstanding performance but the average of all of them has to be good. In order to increase the number of functions on an integrated circuit, the power supply and current consumption are permanently decreasing. The aim of the designed circuits is to double the figure of merit (FOM) of the actual ST portfolio products. The FOM allows the comparison of similar opamps. It is defined by the ratio of the product of capacitive load x gain-bandwith product over the power consumption. The opamps’ state of the art has led this study to three stages analog cells. A DC gain higher than hundreds of decibel is required to use opamps in feedback configuration. As each stage of the structure introduces a high impedance node and as each high impedance node introduces a pole, the study of frequency compensation technics became essential for well optimized structures. To simplify the study of the opamps, three tools have been developed to help in the design of the frequency compensation network and to automate some tasks. This work has been followed by the realization of six cells. Three of them were designed to validate frequency compensation structure and the other three to satisfy a standard opamp datasheet. Nested Miller, Reversed Nested Miller and Multipath Nested Miller compensations were used in these circuits.

Network-on-chip (NoC) based multi-processor systems-on-chip (MPSoCs) are promising candidates for future multi-processor embedded platforms, which are expected to be composed of hundreds of heterogeneous processing elements (PEs) to potentially provide high performances. However, together with the performances, the systems complexity will increase, and new high level design techniques will be needed to efficiently model, simulate, debug and synthesize them. System-level design (SLD) is considered to be the next frontier in electronic design automation (EDA). It enables the description of embedded systems in terms of abstract functions and interconnected blocks. A promising complementary approach to SLD is the use of models of computation (MoCs) to formally describe the execution semantics of functions and blocks through a set of rules. However, also when this formalization is used, there is no clear way to synthesize system-level models into software (SW) and hardware (HW) towards a NoC-based MPSoC implementation, i.e., there is a lack of system design automation (SDA) techniques to rapidly synthesize and prototype system-level models onto heterogeneous NoC-based MPSoCs. In addition, many of the proposed solutions require large overhead in terms of SW components and memory requirements, resulting in complex and customized multi-processor platforms. In order to tackle the problem, a novel model-based SDA flow has been developed as part of the thesis. It starts from a system-level specification, where functions execute according to the synchronous MoC, and then it can rapidly prototype the system onto an FPGA configured as an heterogeneous NoC-based MPSoC. In the first part of the thesis the HeartBeat model is proposed as a model-based technique which fills the abstraction gap between the abstract system-level representation and its implementation on the multiprocessor prototype. Then details are provided to describe how this technique is automated to rapidly prototype the modeled system on a flexible platform, permitting to adjust the system specification until the designer is satisfied with the results. Finally, the proposed SDA technique is improved defining a methodology to automatically explore possible design alternatives for the modeled system to be implemented on a heterogeneous NoC-based MPSoC. The goal of the exploration is to find an implementation satisfying the designer's requirements, which can be integrated in the proposed SDA flow. Through the proposed SDA flow, the designer is relieved from implementation details and the design time of systems targeting heterogeneous NoC-based MPSoCs on FPGA is significantly reduced. In addition, it reduces possible design errors proposing a completely automated technique for fast prototyping. Compared to other SDA flows, the proposed technique targets a bare-metal solution, avoiding the use of an operating system (OS). This reduces the memory requirements on the FPGA platform comparing to related work targeting MPSoC on FPGA. At the same time, the performance (throughput) of the modeled applications can be increased when the number of processors of the target platform is increased. This is shown through a wide set of case studies implemented on FPGA. / <p>QC 20140609</p>

The Cold-Electron Bolometer (CEB) is a sensitive detector of millimeter-wave radiation, in which tunnel junctions are used as temperature sensors of a nanoscale normal metal strip absorber. The absorber is fed by an antenna via two Superconductor-Insulator-Normal metal (SIN) tunnel junctions, fabricated at both ends of the absorber. Incoming photons excite electrons, heating the whole electron system. The incoming RF power is determined by measuring the tunneling current through the SIN junctions. Since electrons at highest energy levels escape the absorber through the tunnel junctions, it causes cooling of the absorber. This electron cooling provides electro-thermal feedback that makes the saturation power of a CEB well above that of other types of millimeter-wave receivers. The key features of CEB detectors are high sensitivity, large dynamic range, fast response, easy integration in arrays on planar substrates, and simple readout. The high dynamic range allows the detector to operate under relatively high background levels. In this thesis, we present the development and successful operation of CEB, focusing on the fabrication technology and different implementations of the CEB for efficient detection of electromagnetic signals. We present the CEB detector integrated across a unilateral finline deposited on a planar substrate. We have measured the finline-integrated CEB performance at 280-315 mK using a calibrated black-body source mounted inside the cryostat. The results have demonstrated strong response to the incoming RF power and reasonable sensitivity. We also present CEB devices fabricated with advanced technologies and integrated in log-periodic, double-dipole and cross-slot antennas. The measured CEB performance satisfied the requirements of the balloon-borne experiment BOOMERANG and could be considered for future balloon-borne and ground-based instruments. In this thesis we also investigated a planar phase switch integrated in a back-to-back finline for modulating the polarization of weak electromagnetic signals. We examine the switching characteristics and demonstrate that the switching speed of the device is well above the speed required for phase modulation in astronomical instruments. We also investigated the combination of a detector and a superconducting phase switch for modulating the polarization of electromagnetic radiation.

Um equipamento sinalizador luminoso de faltas foi desenvolvido pela Companhia Paulista de Força e Luz (CPFL) em parceria com a Escola Politécnica da USP e a empresa Expertise Engenharia Ltda., através de uma série de projetos de pesquisa incluídos no programa de pesquisa e desenvolvimento (P&D) regido pela Agência Nacional de Energia Elétrica (ANEEL) brasileira. Neste trabalho é feita uma análise crítica da rota tecnológica adotada no desenvolvimento do sinalizador de faltas, apontando detalhes e justificativas das escolhas tecnológicas adotadas, além de novas possibilidades de melhoria do equipamento face aos avanços tecnológicos detectados nos últimos anos. Para tanto, é proposto e aplicado um novo método, associado a uma sistematização, para análise comparativa de tecnologias, que considera dados quantitativos, qualitativos e estratégicos diretamente comparáveis entre si. Ao longo do trabalho são analisados as escolhas dos princípios de detecção de faltas e funcionalidades agregadas, o desenvolvimento da eletrônica e dos circuitos integrados do detector de faltas, a fonte de alimentação, a sinalização luminosa e o gabinete do equipamento. Como resultado da linha de pesquisa do sinalizador luminoso de faltas foram obtidos protótipos de prova de conceito, cabeça-de-série e de lote pioneiro, estes últimos prontos e certificados para inserção no mercado. Obtiveram-se também diversas publicações em congressos nacionais, a geração de dois pedidos de patentes e um sistema computacional de alocação otimizada de sinalizadores de faltas em redes de distribuição aérea de energia elétrica. / Within the R&D program governed by the National Agency of Electric Energy of Brazil, a luminous faulted circuit indicator equipment (FCI) was developed by the Companhia Paulista de Força e Luz (CPFL) in partnership with the Escola Politécnica da USP and the company Expertise Engenharia Ltda. In this work it is presented a critical analysis of the technological route adopted for development of this new FCI, indicating details and justifications of technological choices adopted, and new detected possibilities for improvements, taken into account the technological advances in recent years. For such purpose, it is proposed a new method, associated to a practical systematization, for comparative analysis of technologies that accounts for quantitative, qualitative and strategic data directly comparable. The work presents analyses on the choices of fault detection principles and related functions, the development of integrated circuits and fault detector electronics, the power supply, the luminous signaling and the equipment case. As results of the research and development of the FCI there were obtained proof of concept, prototype and pilot equipments, the last ones certified and ready for sale. There were also obtained several publications in national conferences, submission of two patent applications and a software for optimization of FCIs allocation on overhead power distribution networks.

Les domaines d'application de la cryptographie embarquée sont très divers et se retrouvent au croisement de toutes les applications personnelles, avec un besoin évident de confidentialité des données et également de sécurité d'accès des moyens de paiement. Les attaques matérielles invasives ont fait de tous temps partie de l'environnement industriel. L'objectif de cette thèse est de proposer de nouvelles solutions pour protéger les circuits intégrés contre ces attaques physiques. La première partie décrit les notions d'attaques par canaux cachés, d'attaques invasives et de retro-conception. Plusieurs exemples de ces types d'attaques ont pu être mis en œuvre pendant le travail de recherche de cette thèse, ils sont présentés en détail dans cette partie. La deuxième partie est consacrée à des propositions de différentes contre-mesures pour contrer des attaques par canaux cachés ayant pour vecteur la consommation de courant. La troisième partie est dédiée à la protection contre les attaques invasives en utilisant divers types de boucliers et capteurs. Nous conclurons ce manuscrit de thèse par la proposition d'un bouclier actif cryptographique inviolable ayant pour but premier de contrer Je sondage, mais aussi celui de détecter l'injection de fautes et d'être immunisé contre les analyses par consommation de courant. / Embedded security applications are diverse and at the center of all personal embedded applications. They introduced an obvious need for data confidentiality and security in general. Invasive attacks on hardware have always been part of the industrial scene. The aim of this thesis is to propose new solutions in order to protect embedded circuits against some physical attacks described above. ln a first part of the manuscript, we detail the techniques used to achieve side-channel, invasive attacks and reverse engineering. I could implement several of these attacks during my thesis research, they will be detailed extensively. ln the second part we propose different hardware countermeasures against side-channel attacks. The third part is dedicated to protection strategies against invasive attacks using active shielding and we conclude this work by proposing an innovative cryptographic shield which is faulty and dpa resistant.

A la différence de la conception numérique, la conception analogique souffre d’un réel retard au niveau de la solution logicielle qui permet une conception à la fois rapide et fiable. Le dimensionnement de circuits analogiques exige en effet un nombre assez élevé de simulations et de vérifications et dépend beaucoup de l’expertise du concepteur. Pour pallier à ce retard, des outils de conception automatique basés sur des algorithmes d’optimisation locale et globale sont développés. Ces outils restent encore immatures car ils n’offrent que des réponses partielles aux questions du dimensionnement, alors que l’obtention d’un dimensionnement optimal d’un circuit analogique en un temps raisonnable reste toujours un enjeu majeur. La réduction du temps de conception de circuits analogiques intégrés nécessite la mise en place de méthodologies permettant une conception systématique et automatisable sur certaines étapes. Dans le cadre de cette thèse, nous avons travaillé suivant trois approches. Il s’agit d’abord de l’approche méthodologique. A ce niveau nous préconisons une approche hiérarchique descendante « top-down ». Cette dernière consiste à partitionner le système à dimensionner en sous blocs de fonctions élémentaires dont les spécifications sont directement héritées des spécifications du niveau système. Ensuite, nous avons cherché à réduire le temps de conception à travers l’exploration de solutions optimales à l’aide des algorithmes hybrides. Nous avons cherché à profiter de la rapidité de la recherche globale et de la précision de la recherche locale. L’intérêt des algorithmes de recherche hybride réside dans le fait qu’ils permettent d’effectuer une exploration efficace de l’espace de conception du circuit sans avoir besoin d’une connaissance préalable d’un dimensionnement initial. Ce qui peut être très intéressant pour un concepteur débutant. Enfin, nous avons travaillé sur l’accélération du temps des simulations en proposant l’utilisation des méta-modèles. Ceux-ci présentent un temps de simulation beaucoup plus réduit que celui des simulations des modèles électriques. Les méta-modèles sont obtenus automatiquement depuis une extraction des résultats des simulations électriques. / Contrary to digital design, analog design suffers from a real delay in the software solution that enables fast and reliable design. In this PhD, three approaches are proposed. The first is the methodological approach. At this level we recommend a "top-down" hierarchical approach. It consists of partitioning the system to size into sub-blocks of elementary functions whose specifications are directly inherited from the system level specification. Next, we aimed to reduce design time through the exploration of optimal solutions using hybrid algorithms. We attempted to take advantage of the rapid global search and local search accuracy. The interest of hybrid search algorithms is that they allow to conduct effective exploration of the design space of the circuit without the need for prior knowledge of an initial design. This can be very useful for a beginner designer. Finally, we worked on the acceleration of time simulations proposing the use of meta-models which present a more reduced time than electrical simulation models. Meta-models are obtained automatically from extracting results of electrical simulations.

在繁忙的工商界，資訊代表一種情報、一種利器，如何掌握商情資訊，是企業界提昇競爭力的不二法門。IC設計業為一知識密集產業，有鑑於資訊流通、知識管理的重要性，IC設計公司成立公司圖書館（資料單位），以便於有效地保存資料，迅速提供資訊服務。本研究採用深度訪談與問卷調查法，以18家IC設計業公司圖書館為研究對象，目的在瞭解IC設計業公司圖書館的經營狀況，以及在公司知識管理中所扮演的角色。 本調查發現，IC設計業公司圖書館尚屬於起步階段，需協助公司進行品質管理，參與ISO9001的認證，所以主管單位為品保部門；人員編制少，多為一人圖書館，但服務對象卻涵蓋全公司、客戶與晶圓廠；公司圖書館蒐集資料的來源包含客戶、晶圓廠、研究機構以及公司的內部文件與研發資料，並為公司圖書館內的資源製作索引，以提供查詢、借閱。在知識管理的角色扮演上，目前IC設計業公司圖書館已掌握的資源為技術知識，以及公司內已經外顯化的知識，對於資訊知識與內隱知識，尚缺乏管理。 根據調查結果，提出以下五點建議，供IC設計業公司圖書館經營之參考：1.進行文件管理，協助品質認證；2.加強專利資料的蒐尋，實行專利、智慧財產權的管理；3.加入館際合作組織，彌補資源不足的現況；4.強調知識管理的理念，為IC設計公司整合圖書資訊系統；5.館員需要培養主動積極的態度，以知識管理者自居，經常與外界接觸，思考公司圖書館未來經營的方向，並爭取主管與工作同仁的支持與認同、協助蒐集資源。此外，在圖書資訊學系所課程部份，應建立建教合作的關係，重新規畫專門圖書館教育的課程，使圖書資訊學的專長，能運用在公司企業的資料管理。

Die gemeinsame Integration von Bildsensor und analoger hochparalleler Verarbeitungseinheit stellt eine Möglichkeit zur Realisierung von leistungsfähigen ein-chip Bildaufnahmesystemen dar. Die vorliegende Arbeit liefert Beiträge zum systematischen Entwurf von derartigen Systemen und analysiert bekannte und neuartige Schaltungstechniken bezüglich ihrer Eignung für deren Implementierung. Anhand des vom Autor mitentwickelten CMOS-Bildsensors mit hochparalleler analoger Bildverarbeitungseinheit werden die vorgestellten Methoden und Schaltungstechniken demonstriert. Die Problematik beim Entwurf hochparalleler analoger Systeme besteht in der im Vergleich zu digitalen Systemen geringen Automatisierbarkeit. Es ist kein top-down-Entwurf möglich, da nicht jede beliebige Funktion mit beliebiger Genauigkeit realisierbar ist. Um die jeweilige Genauigkeit der Funktionsblöcke bei der Analyse des hochparallelen Systems berücksichtigen zu können, sind rechenaufwendige Simulationen nötig. Um diesen Rechenaufwand zu senken, wird vorgeschlagen, für die Simulation des Gesamtsystems einen angepaßten Simulator und für die Analyse der schaltungstechnischen Realisierung der Funktionsblöcke konventionelleWerkzeuge für elektrische Netzwerke zu verwenden. Die beiden Simulationsdomänen werden mit Hilfe von numerischen Verhaltensmodellen verbunden. Durch diese Trennung wird die Simulation des Gesamtsystems als Bestandteil des Entwurfsflusses praktikabel. Für die Bewertung, inwieweit die zufälligen Schwankungen der Bauelementeparameter das Verhalten von Baublöcken beeinflussen, wird die Varianzanalyse als Alternative zur konventionellen Monte-Carlo-Analyse vorgeschlagen. Die Varianzanalyse ist wesentlich weniger rechenaufwendig und liefert genaue Resultate für alle Schaltungseigenschaften mit hinreichend glatten Parameterabhängigkeiten, wenn die Bauelementeparameter als normalverteilt und statistisch unabhängig angenommen werden können. Sie hat darüberhinaus den Vorteil, das Schaltungsverständnis für den Entwerfer zu erhöhen, da sofort die Bauelementeparameter mit dem größten Einfluß auf das Schaltungsverhalten identifiziert werden können. Der Vergleich verschiedener Schaltungstechniken hat gezeigt, daß zeitdiskrete wertkontinuierliche Verfahren, bei denen die Information als Strom repräsentiert wird, für die Realisierung von hochparallelen analogen Systemen besonders geeignet sind. Als besonderer Vorteil ist die weitestgehende Unabhängigkeit des Verhaltens derartiger Schaltungen von Bauelementeparametern hervorzuheben.Weitere Schaltungstechniken, deren Verhalten von zufälligen Parameterabweichungen nur wenig beeinflußt werden, sind in einer Taxonomie zusammengefaßt. Es wurde ein CMOS-Bildsensor mit hochparalleler analoger Bildverarbeitungseinheit und digitaler Ausgabe realisiert. Der current-mode-Bildsensor ist separat von der Verarbeitungseinheit angeordnet. Es wurden vier verschiedene Realisierungsmöglichkeiten untersucht und eine konventionelle integrierende voltage-mode Pixelzelle mit nachfolgendem differentiellen Spannungs- Strom-Wandler realisiert. Das Rechenfeld ist für die räumliche Faltung oder lineare Transformation von Bilddaten mit digital bereitzustellenden Koeffizienten ausgelegt. Dessen Operation basiert auf einer bit-weisen analogen Verarbeitung. Der Schaltkreis wurde erfolgreich getestet. Die nachgewiesene Bildqualität deckt sich in guter Näherung mit den bei der Simulation des Gesamtsystems getroffenen Vorhersagen / The joined implementation of an image sensor and a highly parallel analog processing unit is an advantageous approach for realizing efficient single-chip vision systems. This thesis proposes a design flow for the development of such systems. Moreover known and novel circuit techniques are analysed with respect for their suitability for the implementation of highly parallel systems. The presented methodologies and circuit techniques are demonstrated at the example of a CMOS image sensor with an embedded highly parallel analog image processing unit in whose design the author was involved. One of the major problems in designing highly parallel analog circuits is the low automation compared to the design of digital circuits. As not every function can be realized with arbitrary accuracy top-down-design is not feasible. So, when analysing the system behaviour the respective precision of each function block has to be considered. As this is a very demanding task in terms of computing power, it is proposed to use a dedicated tool for the simulation of the system and conventional network analysis tools for the inspection of the circuit realizations. Both simulation domains are combined by means of numerical behavioural models. By using separate tools system-simulations of highly parallel analog systems as a part of the design flow become practicable. Variance analysis basing on parameter sensitivities is proposed as an alternative to the conventional Monte-Carlo-analysis for investigating the influence of random device parameter variations on the system behaviour. Variance analysis requires much less computational effort while providing accurate results for all circuit properties with sufficiently smooth parameter dependencies if the random parameters can be assumed normally distributed and statistically independent. Additionally, variance analysis increases the designer’s knowledge about the circuit, as the device parameters with the highest influence on the circuit performance can immediately be identified. The comparison of various circuit techniques has shown, that sampled-time continuous-valued current-mode principles are the best choice for realizing highly parallel analog systems. A distinctive advantage of such circuits is their almost independence from device parameters. A selection of further circuit techniques with low sensitivity to random device parameter variations are summarized in a taxonomy. A CMOS image sensor with embedded highly parallel analog image processing unit has been implemented. The image sensor provides a current-mode output and is arranged separate from the processing unit. Four different possibilities for realizing an image sensor have been analysed. A conventional integrating voltage-mode pixel cell with a succeeding differential voltage- to-current-converter has been selected. The processing unit is designed for performing spatial convolution and linear transformation with externally provided digital kernels. It operates in bit-wise analog manner. The chip has been tested successfully. The measured image quality in good approximation corresponds with the estimations made with system simulations.