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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

Sjuksköterskans erfarenhet av framprovocerade tvångsåtgärder inom psykiatrisk slutenvård : En kvalitativ intervjustudie / Nurses’experiences of provoked coercive measures in psychiatric inpatient care : a qualitative interview study

Osein, Michelle, Ingvarsson, Sebastian January 2022 (has links)
Bakgrund: Tvångsåtgärder är en omdiskuterad intervention och leder till att patientens autonomi åsidosätts. Personal kan medvetet eller omedvetet framprovocera situationer som kan leda till tvångsåtgärder. Syfte: Syftet med studien var att undersöka sjuksköterskans erfarenheter av framprovocerade tvångsåtgärder inom psykiatrisk slutenvård. Metod: En kvalitativ intervjustudie utfördes där nio sjuksköterskor intervjuades. En kvalitativ innehållsanalys med induktiv ansats genomfördes vilket gav tre slutkategorier. Resultat: Resultatet beskrev varför framprovocerade tvångsåtgärder uppstår, hur tvångsåtgärder provoceras fram av personal samt hur framprovocerade tvångsåtgärder kan undvikas. Framprovocerade tvångsåtgärder kunde uppstå när personal inte hade tålamod, kunskap eller tillämpande personalperspektivet. En vårdkultur som präglades av machokultur kunde leda till framprovocerade tvångsåtgärder. Genom att arbeta förebyggande med alternativa lösningar, ha ett lågaffektivt bemötande och ha rätt kompetens och kunskap på avdelningen kunde framprovocerade tvångsåtgärder undvikas. Slutsats: En djupare förståelse för varför och hur framprovocerade tvångsåtgärder uppkommer framkom men även hur preventivt arbete kunde utföras. Framprovocerade tvångsåtgärder är ett område som kan vara svårt att prata om men som är viktigt att belysa. Genom den ökade kunskapen hoppas författarna möjliggöra reflektion på arbetsplatserna och att vidare forskning utförs i syfte att belysa området.
42

Provocation et vérité. Forme et sens des paradoxes stoïciens dans la poésie latine, chez Lucilius, Horace, Lucain et Perse / Provocation and truth. Form and sense of Stoic paradoxes in Latin poetry, by Lucilius, Horace, Lucan and Persius

Demanche, Diane 01 July 2011 (has links)
La présence des paradoxes stoïciens dans l’œuvre de poètes dont les liens avec le Portique sont divers révèle le statut particulier occupé par ces formules déconcertantes dans la pensée romaine. Après l’étude des origines du paradoxe et de ses transformations au cours du développement des écoles philosophiques grecques, la thèse examine la spécificité du paradoxe stoïcien et son adaptation au monde romain. Contre toute attente, les Stoïciens ne renoncent pas à ces affirmations déconcertantes. Grâce à leur efficacité rhétorique, et malgré l’hostilité qu’ils suscitent par ailleurs, les paradoxes sont repris dans des textes étrangers au Portique. Leur adaptation dans des œuvres poétiques - satires de Lucilius, Horace et Perse, épodes, odes et épîtres d’Horace et épopée lucanienne - pourrait nous faire considérer qu’ils sont pervertis et détournés de leur fin première. En effet, le but de ces poètes n’est nullement de faire adhérer le lecteur à l’intransigeante perfection dessinée par les paradoxes stoïciens. Mais le lien entre les paradoxes que l’on trouve dans ce corpus poétique et leur origine stoïcienne est en réalité bien plus intime. Selon des modalités différentes, chaque poète reprend l’essentiel de la démarche paradoxale du Portique : il s’agit bien de réveiller les consciences, et de souligner la radicale nouveauté de la vérité que l’on veut faire entendre, tout en s’assurant que le lecteur peut s’y rallier. La virulence de Lucilius, le ton de confidence horatien, la stupeur lucanienne et l’obscurité de Perse constituent les voies distinctes mais convergentes par lesquelles est menée l’entreprise subtile consistant à choquer pour mieux convertir. / The presence of Stoic paradoxes in the works of poets whose links with the Stoa are complex reveals the particular status of these incongruous formulas in Roman thought. After studying the origins of paradox and its transformations during the development of the Greek philosophical schools, the thesis considers the particularity of Stoic paradox and its adaptation to the Roman world. Unexpectedly, the Stoics do not sign away these disconcerting assertions. By their rhetorical effectiveness, and despite the hostility they also arouse, paradoxes appear in texts which do not belong to the Stoa. Their adaptation in poetic works – satires of Lucilius, Horace and Persius, epodes, odes and epistles of Horace, and Lucanian epic - could make us consider that they are perverted and diverted from their first aim. Indeed, the purpose of these poets is not at all to have the reader adhere to the uncompromising perfection outlined by the Stoic paradoxes. But the link between the paradoxes we find in this poetic corpus and their Stoic origin is actually much more intimate. By different ways, each poet takes up the main of the Stoic paradoxical approach : it consists in waking up the minds, and showing the radical novelty of the truth which one wants to reveal, making sure, at the same time, that the reader can join it. Lucilius’ virulence, Horace’s intimacy, Lucan’s daze and Persius’ abstruse language constitute the different but converging ways by which one subtly undertakes to shock in order to convert.
43

Trestněprávní aspekty policejní provokace / Criminal law aspects of police provocation

Šulda, Pavel January 2021 (has links)
1 Criminal law aspects of police provocation Abstract in English This diploma thesis deals with definition of possibly the most exact limit between legal entry of prosecuting authorities to the factual act of the crime and inadmissible police provocation. Following this determination of the limits, which is the main aim of the thesis, it gives the tightest definition of police provocation, it solves possible criminal law consequences of police provocation and it brings a brief analysis of admissibility of further forms of behaviour that can result in an intention of other person to commit a crime. For this purpose the thesis is divided into 4 chapters. The first chapter deals with the problem of police provocation in a broader context of fight against organized crime. It is highlighted the necessity of really careful consideration of the tools and the amount of their usage when fighting organized crime so that their deployment means tolerable rate of interference with human rights and freedoms. The second chapter follows, which deals with general introduction of tools used to fight not only organized crime. These are operational and investigative acitons and supportive operational and investigative actions, using which there most often comes to police provocation. In case of operational and investigative...
44

Avaliação da função pulmonar e investigação da asma alérgica em pacientes com imunodeficiência comum variável / Pulmonary function and screening for allergic asthma in patients with common variable immunodeficiency

Leite, Rosana Camara Agondi 26 August 2008 (has links)
A imunodeficiência comum variável (ICV) é uma síndrome heterogênea caracterizada por hipogamaglobulinemia e infecções bacterianas de repetição. As doenças obstrutivas, como a asma, estão presentes em aproximadamente 50% dos pacientes. Os sintomas decorrentes de infecções respiratórias de repetição podem mascarar os sintomas de alergia respiratória. A asma tem alta prevalência no mundo e é observada em aproximadamente 10% da população brasileira. Embora muitos pacientes com ICV apresentem história clínica sugestiva de rinite e/ou asma alérgicas, a participação da atopia não está bem esclarecida e freqüentemente os níveis de IgE total e/ou IgE específica estão baixos. Muitos autores estudam a produção de IgE local e uma correlação entre a concentração de IgE nos fluidos corporais e no soro existe. Os objetivos deste estudo são avaliar a função pulmonar em pacientes com ICV através de: espirometria, provocação brônquica com histamina e com alérgeno; investigar o diagnóstico de asma em pacientes com ICV e realizar a investigação in vivo e in vitro da IgE em pacientes com ICV. Este estudo incluiu 62 pacientes que estavam em acompanhamento ambulatorial no Serviço de Imunologia Clínica e Alergia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. A função pulmonar foi avaliada pela espirometria e pela provocação brônquica com histamina antes e após uma provocação brônquica com Dermatophagoides pteronyssinus (Der p) e a investigação da IgE específica para aeroalérgenos através de teste epicutâneo e avaliação da IgE sérica específica usando ImmunoCAPTM. Vinte e nove (46,7%) tinham história clínica de sugestiva de asma e em relação à atopia, 27 (43,5%) tinham história sugestiva de atopia. Uma associação de asma e atopia no mesmo paciente foi encontrada em 18 pacientes (29%). Nós comparamos o grupo sugestivo de asma alérgica com os outros pacientes pacientes com rinite alérgica ou não-alérgica, asma não-alérgica e pacientes sem sintomas respiratórios. A maioria dos pacientes apresentou níveis séricos de IgE total indetectáveis. Somente dois pacientes apresentaram resultado positivo para IgE específica pelo teste epicutâneo e in vitro. Sessenta e um pacientes realizaram espirometria. Destes, 25 pacientes (41%) apresentaram resultado normal, 29 (47,5%) apresentaram distúrbio ventilatório obstrutivo e 7 (11,5%) apresentaram resultados sugestivos de distúrbio ventilatório restritivo. As provocações brônquicas foram realizadas em 15 pacientes. A provocação brônquica com histamina foi considerada positiva em 3 pacientes com história positiva para asma. Em relação à provocação brônquica com Der p, nenhum paciente apresentou resposta imediata positiva. Entretanto, quando a segunda provocação brônquica com histamina foi realizada (pós-Der p), quatro dos 5 pacientes com história sugestiva de asma alérgica apresentaram resultado positivo, com diminuição de PC20 em relação à primeira provocação vi brônquica com histamina. Uma diferença estatística foi observada nos resultados entre o grupo sugestivo de asma alérgica e os pacientes sem asma alérgica. Ao final do estudo, a asma foi confirmada em 9 pacientes com ICV (14,5%), a atopia foi confirmada em 6 pacientes com ICV (9,7%) e a asma alérgica foi confirmada em 4 pacientes com ICV (6,5%), que correspondeu a 22,2% dos 18 pacientes com suspeita de asma alérgica / Common variable immunodeficiency (CVID) is a heterogenous immunodeficiency syndrome characterized by hypogammaglobulinemia, and recurrent bacterial infections. Obstructive diseases as asthma are present in approximately 50 % of patients. Symptoms due to recurrent respiratory pyogenic infections may mask respiratory allergic symptoms. Asthma has high worldwide prevalence and is observed in approximately 10 % of Brazilian population. Although a number of patients with CVID report a clinical history suggestive of allergic symptoms, the role of atopy is not well established in these individuals; and frequently levels of total IgE and/or specific IgE are low. Local IgE production has been studied and a correlation between IgE concentration in body fluids and serum exists. The objectives of this study are evaluation of pulmonary function in patients with CVID through: spirometry, bronchial challenge with histamine, and with allergen; investigate asthma diagnosis in patients with CVID; perform in vivo and in vitro investigation of IgE in patients with CVID. This study included sixty-two patients, who were being followed at the Service of Clinical Immunology and Allergy of the Hospital das Clínicas of the University of São Paulo Medical School. Pulmonary function was assessed using spirometry and bronchial challenge with histamine before and after a bronchial challenge with Dermatophagoides pteronyssinus (Der p), and investigation of specific IgE for aeroallergens with skin prick test and serum specific IgE evaluation using ImmunoCAPTM. Twenty-nine (46.7 %) had clinical history suggestive of asthma, and in regards to atopy, twenty-seven patients (43.5%) reported atopy suggestive history. An association of asthma and atopy in the same patient was observed in eighteen (29 %) participants. We compared the group of allergic asthma with the other patients patients with allergic or non-allergic rhinitis, non-allergic asthma, and patients without respiratory. Most patients had undetectable levels of total IgE concentration in serum. Only two patients had positive results for specific IgE by prick test and in vitro investigation. All patients, except one, underwent spirometry test for lung function evaluation. Of the sixty-one patients, twenty-five (41 %) had normal spirometry results, twenty-nine (47.5 %) had Obstructive Ventilatory Defect, and seven (11.5 %) had results suggestive of Restrictive Ventilatory Defect. Bronchial challenges were performed in fifteen patients. Bronchial challenge with histamine was considered positive in three patients with a positive history of asthma. Regarding to bronchial challenge with Der p, none presented immediate positive response. However, when the second nonspecific bronchial provocation with histamine was performed (post-Der p), four of the five patients with a history of allergic asthma had positive test results, with lower PC20 than in the first non-specific bronchial provocation with histamine. A statistical difference was noticed in the test results of the group suggestive for allergic asthma and the patients without allergic asthma. viii At the end of this study, asthma had been confirmed in 9 patients with CVID (14.5%), atopy had been confirmed in 6 patients with CVID (9.7%), and allergic asthma had been confirmed in 4 patients with CVID (6.5%), which corresponded to 22.2% of the 18 patients suspected of allergic asthma
45

La provocation expérimentale : étude consacrée à la provocation expérimentale dans l'art et à son usage dans une pratique artistique

Louvel, Romain 29 October 2010 (has links) (PDF)
La provocation expérimentale est ce geste qui consiste à introduire un élément perturbateur dans les rouages d'un système pour en révéler la structure, l'organisation et leurs déterminants. Nous partons de l'hypothèse selon laquelle cette technique s'applique aussi à la pratique artistique. Or, cette hypothèse mérite d'être examinée au regard de l'histoire de l'art et de notre « pratique sociale artistique ». Dans cette perspective, la provocation expérimentale est considérée comme un phénomène intrinsèque de la nature révolutionnaire de l'art. Dans un premier temps, nous découvrons la provocation expérimentale en tant que technique sociologique. Les risques de perturber l'espace social, encourus par le sociologue, accompagnent favorablement la présence dérangeante de l'artiste dans la société. Ils accentuent la portée critique des oeuvres, laquelle est soutenue par le problème que pose le statut objectif du représentant (l'oeuvre) en face de ce qui est représenté (la nature et ses sujets). L'intérêt théorique de la provocation expérimentale instigatrice de diversion réside dans la question du projet social de l'art. Ensuite, nous considérons les signes de la provocation expérimentale dans l'histoire de l'art à partir de la fin du XIXe siècle. Par quels moyens diversifiés les artistes développent-ils des méthodes, des stratagèmes, des engagements esthétiques, sociaux et politiques ? Il ne résulte cependant pas de cet éclairage qu'il existe un courant de l'art rattachée explicitement à la pratique de la provocation expérimentale. L'usage coutumier que les artistes font de la pratique du scandale n'apparaît pas non plus comme un signe pertinent. Finalement, nous pensons que les mécanismes de la provocation expérimentale sont présents dans la nature de l'oeuvre d'art et son rapport au monde. Après cela, nous définissons le phénomène de la rupture des routines du quotidien comme mécanisme clef de la provocation expérimentale. Quelle signification impliquent les effets et les enjeux d'une intervention de l'art de cette nature au sein de la société ? Cette question offre la possibilité de réfléchir sur un projet artistique concret engagé dans le processus social. Pour finir, notre description théorique de la provocation expérimentale converge vers l'analyse de projets artistiques récents qui ont permis de formaliser cette thèse. En effet, ces projets sont à notre initiative et tiennent lieu de point de départ empirique. En utilisant le concept de la provocation expérimentale pour saisir le sens de nos expériences artistiques, nous dévoilons des indicateurs concrets d'une esthétique inscrite dans le projet plus large de l'éducation populaire
46

Neural Circuitry in Obsessive Compulsive Disorder: an fMRI Study of the Effect of IV Citalopram

Bhikram, Tracy Prema 21 November 2012 (has links)
Background: Functional imaging studies have examined the neural circuitry of subjects with obsessive compulsive disorder (OCD), and the changes associated with oral treatment. However, the effect of intravenous (IV) serotonin reuptake inhibitors (SRIs) on neuronal activation has not been investigated in OCD subjects, even though IV SRIs have been shown to be more effective than oral pharmacotherapy. Methods: Six OCD and 6 control subjects underwent functional magnetic resonance imaging while receiving infusions of citalopram and placebo, in a randomized, crossover design. Results: Compared to controls, OCD subjects exhibited hyperactivation of the orbitofrontal cortex and anterior cingulate cortex while looking at symptom provoking pictures at baseline. However, after the citalopram infusion, patients displayed attenuations of these regions, which correlated with reductions in subjective anxiety ratings. Conclusion: The effects observed after the IV citalopram infusion are similar to modulations observed after prolonged oral pharmacotherapy trials, illustrating the benefits of IV SRIs.
47

Neural Circuitry in Obsessive Compulsive Disorder: an fMRI Study of the Effect of IV Citalopram

Bhikram, Tracy Prema 21 November 2012 (has links)
Background: Functional imaging studies have examined the neural circuitry of subjects with obsessive compulsive disorder (OCD), and the changes associated with oral treatment. However, the effect of intravenous (IV) serotonin reuptake inhibitors (SRIs) on neuronal activation has not been investigated in OCD subjects, even though IV SRIs have been shown to be more effective than oral pharmacotherapy. Methods: Six OCD and 6 control subjects underwent functional magnetic resonance imaging while receiving infusions of citalopram and placebo, in a randomized, crossover design. Results: Compared to controls, OCD subjects exhibited hyperactivation of the orbitofrontal cortex and anterior cingulate cortex while looking at symptom provoking pictures at baseline. However, after the citalopram infusion, patients displayed attenuations of these regions, which correlated with reductions in subjective anxiety ratings. Conclusion: The effects observed after the IV citalopram infusion are similar to modulations observed after prolonged oral pharmacotherapy trials, illustrating the benefits of IV SRIs.
48

Pollinosis in children with special reference to the development of asthma /

Ferdousi, Hosne Ara, January 2004 (has links) (PDF)
Diss. Linköping : Linköpings universitet, 2004. / Härtill 7 uppsatser.
49

Recensera mig du kåta man

Brask, Jessica, Hedberg, Frida January 2016 (has links)
Vi har i detta kandidatarbete gjort en deltagande observation på en hemsida där sexuella tjänster annonseras ut. På hemsidan finns det ett forum där sexköpare och sexsäljare diskuterar sina tankar om sex och köp av sexuella tjänster. Ofta uttrycker sig sexköparna som om de vore offer i sexbranschen och inte kan hjälpa att de har en stark sexualdrift. De skyller på att det så länge det finns ett utbud av sexuella tjänster, kommer att finnas en efterfrågan på att köpa sexuella tjänster. Vi har också lagt märke till att det finns en acceptans hos sexköparna när det gäller när det gäller personer som skaffar sig en tillfällig sexuell förbindelse mot ersättning och att kåta okontrollerade män ofta håller varandra om ryggen.I motsats till sexköparna anser vi att så länge det finns en efterfrågan på köp av sexuella tjänster kommer också marknaden för sexuell trafficking att finnas. Detta eftersom många som är offer för sexuell trafficking annonseras ut som om att de säljs av fri vilja. Av den anledningen kommer vi i detta kandidatarbete problematisera kring kring sexuell trafficking som en konsekvens av sexköparens handlingar. Vi vill som medieproducenter, genom bilder, belysa sexköparens ansvar samtidigt som vi synliggör samhällsproblemet sexuell trafficking med hjälp av provokativ nätaktivism. / In this bachelor essay we´ve made an participant observation on a website where sexual services are for sale. This website contains a forum where sexbuyers and sexsellers discuss their thoughts about sex and purchase of sexual services. Sexbuyers often express themselves as victims because of their own extreme sexual cravings. They argue that as long as there is sexual services for sale, there is going to be a demand to buy them. We notice that there is an acceptance for sexbuyers to have an temporary sexual relation in exchange for money. We notice in our studies that these so called “intemperated horny men” tend to protect one another.We consider, in contrast to the sexbuyers, that as long as there is an existing “craving” for sexual services, the phenomenon of sexual trafficking will continue. Much because many victims of sexual trafficking are being sold as if it was by their own free will. Because of this, we will in this bachelor essay problematize sexual trafficking as a consequence of sexbuyers actions.We as mediaproducers would like to, through pictures, shed light on the consequences of sexual trafficking and at the same time emphasize this through provocative internet activism.
50

Avaliação da função pulmonar e investigação da asma alérgica em pacientes com imunodeficiência comum variável / Pulmonary function and screening for allergic asthma in patients with common variable immunodeficiency

Rosana Camara Agondi Leite 26 August 2008 (has links)
A imunodeficiência comum variável (ICV) é uma síndrome heterogênea caracterizada por hipogamaglobulinemia e infecções bacterianas de repetição. As doenças obstrutivas, como a asma, estão presentes em aproximadamente 50% dos pacientes. Os sintomas decorrentes de infecções respiratórias de repetição podem mascarar os sintomas de alergia respiratória. A asma tem alta prevalência no mundo e é observada em aproximadamente 10% da população brasileira. Embora muitos pacientes com ICV apresentem história clínica sugestiva de rinite e/ou asma alérgicas, a participação da atopia não está bem esclarecida e freqüentemente os níveis de IgE total e/ou IgE específica estão baixos. Muitos autores estudam a produção de IgE local e uma correlação entre a concentração de IgE nos fluidos corporais e no soro existe. Os objetivos deste estudo são avaliar a função pulmonar em pacientes com ICV através de: espirometria, provocação brônquica com histamina e com alérgeno; investigar o diagnóstico de asma em pacientes com ICV e realizar a investigação in vivo e in vitro da IgE em pacientes com ICV. Este estudo incluiu 62 pacientes que estavam em acompanhamento ambulatorial no Serviço de Imunologia Clínica e Alergia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. A função pulmonar foi avaliada pela espirometria e pela provocação brônquica com histamina antes e após uma provocação brônquica com Dermatophagoides pteronyssinus (Der p) e a investigação da IgE específica para aeroalérgenos através de teste epicutâneo e avaliação da IgE sérica específica usando ImmunoCAPTM. Vinte e nove (46,7%) tinham história clínica de sugestiva de asma e em relação à atopia, 27 (43,5%) tinham história sugestiva de atopia. Uma associação de asma e atopia no mesmo paciente foi encontrada em 18 pacientes (29%). Nós comparamos o grupo sugestivo de asma alérgica com os outros pacientes pacientes com rinite alérgica ou não-alérgica, asma não-alérgica e pacientes sem sintomas respiratórios. A maioria dos pacientes apresentou níveis séricos de IgE total indetectáveis. Somente dois pacientes apresentaram resultado positivo para IgE específica pelo teste epicutâneo e in vitro. Sessenta e um pacientes realizaram espirometria. Destes, 25 pacientes (41%) apresentaram resultado normal, 29 (47,5%) apresentaram distúrbio ventilatório obstrutivo e 7 (11,5%) apresentaram resultados sugestivos de distúrbio ventilatório restritivo. As provocações brônquicas foram realizadas em 15 pacientes. A provocação brônquica com histamina foi considerada positiva em 3 pacientes com história positiva para asma. Em relação à provocação brônquica com Der p, nenhum paciente apresentou resposta imediata positiva. Entretanto, quando a segunda provocação brônquica com histamina foi realizada (pós-Der p), quatro dos 5 pacientes com história sugestiva de asma alérgica apresentaram resultado positivo, com diminuição de PC20 em relação à primeira provocação vi brônquica com histamina. Uma diferença estatística foi observada nos resultados entre o grupo sugestivo de asma alérgica e os pacientes sem asma alérgica. Ao final do estudo, a asma foi confirmada em 9 pacientes com ICV (14,5%), a atopia foi confirmada em 6 pacientes com ICV (9,7%) e a asma alérgica foi confirmada em 4 pacientes com ICV (6,5%), que correspondeu a 22,2% dos 18 pacientes com suspeita de asma alérgica / Common variable immunodeficiency (CVID) is a heterogenous immunodeficiency syndrome characterized by hypogammaglobulinemia, and recurrent bacterial infections. Obstructive diseases as asthma are present in approximately 50 % of patients. Symptoms due to recurrent respiratory pyogenic infections may mask respiratory allergic symptoms. Asthma has high worldwide prevalence and is observed in approximately 10 % of Brazilian population. Although a number of patients with CVID report a clinical history suggestive of allergic symptoms, the role of atopy is not well established in these individuals; and frequently levels of total IgE and/or specific IgE are low. Local IgE production has been studied and a correlation between IgE concentration in body fluids and serum exists. The objectives of this study are evaluation of pulmonary function in patients with CVID through: spirometry, bronchial challenge with histamine, and with allergen; investigate asthma diagnosis in patients with CVID; perform in vivo and in vitro investigation of IgE in patients with CVID. This study included sixty-two patients, who were being followed at the Service of Clinical Immunology and Allergy of the Hospital das Clínicas of the University of São Paulo Medical School. Pulmonary function was assessed using spirometry and bronchial challenge with histamine before and after a bronchial challenge with Dermatophagoides pteronyssinus (Der p), and investigation of specific IgE for aeroallergens with skin prick test and serum specific IgE evaluation using ImmunoCAPTM. Twenty-nine (46.7 %) had clinical history suggestive of asthma, and in regards to atopy, twenty-seven patients (43.5%) reported atopy suggestive history. An association of asthma and atopy in the same patient was observed in eighteen (29 %) participants. We compared the group of allergic asthma with the other patients patients with allergic or non-allergic rhinitis, non-allergic asthma, and patients without respiratory. Most patients had undetectable levels of total IgE concentration in serum. Only two patients had positive results for specific IgE by prick test and in vitro investigation. All patients, except one, underwent spirometry test for lung function evaluation. Of the sixty-one patients, twenty-five (41 %) had normal spirometry results, twenty-nine (47.5 %) had Obstructive Ventilatory Defect, and seven (11.5 %) had results suggestive of Restrictive Ventilatory Defect. Bronchial challenges were performed in fifteen patients. Bronchial challenge with histamine was considered positive in three patients with a positive history of asthma. Regarding to bronchial challenge with Der p, none presented immediate positive response. However, when the second nonspecific bronchial provocation with histamine was performed (post-Der p), four of the five patients with a history of allergic asthma had positive test results, with lower PC20 than in the first non-specific bronchial provocation with histamine. A statistical difference was noticed in the test results of the group suggestive for allergic asthma and the patients without allergic asthma. viii At the end of this study, asthma had been confirmed in 9 patients with CVID (14.5%), atopy had been confirmed in 6 patients with CVID (9.7%), and allergic asthma had been confirmed in 4 patients with CVID (6.5%), which corresponded to 22.2% of the 18 patients suspected of allergic asthma

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