INTRODUÇÃO: Diversos ensaios clínicos randomizados (ECR) foram realizados nos últimos anos sobre a eficácia dos agentes biológicos no tratamento da artrite reumatóide (AR). Porém, as revisões sistemáticas sobre o tema ainda geram dúvidas sobre a real eficácia relacionada à capacidade funcional e qualidade de vida. MÉTODOS: O presente estudo sintetizou as evidências geradas pelas revisões sistemáticas que compararam o tratamento realizado com a utilização dos agentes biológicos e o tratamento convencional com a utilização das drogas anti-reumáticas modificadoras da doença de síntese química (DARMDq), considerando a capacidade funcional e qualidade de vida dos pacientes com AR, além de avaliar a qualidade metodológica das revisões sistemáticas recuperadas. Utilizamos as bases de dados PubMed (Medline), EMBASE e Cochrane para realizar o levantamento de revisões sistemáticas com ou sem meta-análises de ECR. Dois pesquisadores de maneira independente realizaram a seleção das revisões sistemáticas, avaliaram a qualidade metodológica utilizando a ferramenta AMSTAR e classificaram a qualidade das evidências pelo GRADE. RESULTADOS: Esta overview incluiu 10 revisões sistemáticas e meta-análises de ECR que avaliaram a capacidade funcional mensurada pelo HAQ e a qualidade de vida mensurada pelo SF-36 (PCF e PCM) em pacientes com AR que utilizaram a terapia com os agentes biológicos comparada a terapia convencional com a utilização das DARMDq. A maioria da revisões sistemáticas apresentaram alta qualidade metodológica avaliada pela ferramenta AMSTAR e a qualidade da evidência variou entre baixa a alta qualidade pelo GRADE. A melhora da capacidade funcional e qualidade de vida observada no período inicial do tratamento (24 semanas) com a terapia biológica, foi de pequena relevância clínica. Esta diferença entre os tratamentos não foi observada no longo prazo (52 semanas), principalmente com os agentes biológicos na forma de monoterapia. CONCLUSÃO: Evidências que variam entre baixa a alta qualidade mostraram que os agentes biológicos apresentaram melhora de baixa relevância clínica na capacidade funcional e qualidade de vida no período inicial do tratamento em comparação à terapia convencional com as DARMDq. Entretanto, não há diferenças entre a utilização da terapia biológica e da terapia convencional a longo prazo / INTRODUCTION: Several randomized clinical trials (RCTs) have been conducted in recent years on the efficacy of biological agents in the treatment of rheumatoid arthritis (RA). However, systematic reviews on this topic still raise doubts about the real efficacy related to functional capacity and quality of life. METHODS: This study synthesized the evidence generated by systematic reviews comparing the treatment with biological agents and the conventional treatment with disease-modifying antirheumatic drugs (DMARD), considering the functional capacity and quality of life of patients with RA, also evaluating the methodological quality of the systematic reviews retrieved. PubMed (Medline), EMBASE and Cochrane databases were searched for systematic reviews with or without RCT meta-analyzes. Two researchers independently carried out the selection of systematic reviews, assessed the methodological quality using the AMSTAR tool and classified the quality of the evidence by GRADE. RESULTS: This overview included 10 systematic reviews and meta-analyzes of RCTs that assessed functional capacity measured by HAQ and quality of life measured by SF-36 (PCS and MCS) in RA patients who used therapy with biological agents compared to conventional therapy with DMARDq. Most of the systematic reviews presented high methodological quality evaluated by the AMSTAR tool and the quality of the evidence ranged from low to high quality by GRADE. The improvement in functional capacity and quality of life observed in the initial period of treatment (24 weeks) with biological therapy presented low clinical relevance. This difference between the treatments was not observed in the long term (52 weeks), mainly with the biological agents in the form of monotherapy. CONCLUSION: Evidence that varied between low to high quality demonstrated that biological agents presented improvement with low clinical relevance of the functional capacity and quality of life during the initial period of treatment compared to conventional therapy with DMARDq. However, there are no differences in the long term between the use of biological therapy and conventional therapy

Made available in DSpace on 2016-01-26T12:51:16Z (GMT). No. of bitstreams: 1 marielza_dissert_parte 1.pdf: 600568 bytes, checksum: 0107e3e73118e6ec5de58894e7163c10 (MD5) Previous issue date: 2004-04-27 / Technological improvements in dialysis have contributed for the increased survival of chronic renal patients, however, undergoing dialysis treatment for an indeterminate time might interfere in the quality of life of these patients. This study was aimed at evaluating the quality of life of chronic renal patients undergoing hemodialysis and identifying the activities that might have a negative impact on their quality of life. This is a descriptive and exploratory study, including 125 chronic renal patients undergoing hemodialysis (74 men and 51 women), mean age 53.1±14.6 years, mean time on hemodialysis 28.5±23 months. The generic SF-36 quality of life questionnaire and a semi-structured interview were used as data collection instruments. Data was subject to a descriptive statistical analysis, the chi-squared test, Pearson s correlation coefficient and the proportion comparison test, with a significance level of 5%. The results showed impaired quality of life of the patients, with lower scores for physical aspects dimensions (32.3±11.3), emotional aspects (46.1±16.3) and vitality (48.7±7.3). Quality of life variables regarding genders did not have a significant difference. There was a negative correlation between time on hemodialysis and physical component (r=-0.75, p<0.001), indicating that the longer the time on hemodialysis the lower are the scores found for this component and there was no significant correlation between time on hemodialysis and mental component (r=-0.29). Physical and recreational activities were the most affected in the global sample and in the sample stratified by gender. There was a negative correlation between time on hemodialysis and daily activities: work (p=0.0014), domestic activities (p=0.0014) and practical activities (0.0459). Data have shown impairment in several of the analyzed quality of life aspects in chronic renal patients undergoing hemodialysis and have pointed out that daily physical and recreational activities were the most affected ones. Our results have allowed the conclusion that there were no evidences of statistically significant differences in quality of life compared to gender; time on hemodialysis correlated with quality of life and daily activities had a negative correlation with physical component and work, domestic and practical activities. These results are important predictive factors to improve quality of life parameters in these patients. / Os avanços tecnológicos na área de diálise contribuíram para o aumento da sobrevida dos renais crônicos, entretanto, a permanência por tempo indeterminado em tratamento dialítico pode interferir na qualidade de vida destes pacientes. Este estudo teve como objetivo avaliar a qualidade de vida de pacientes renais crônicos em tratamento de hemodiálise e identificar as atividades cotidianas, que podem comprometer na qualidade de vida. Trata-se de estudo descritivo e exploratório, onde foram pesquisados 125 pacientes renais crônicos em tratamento de hemodiálise (74 homens e 51 mulheres), com média de idade 53,114,6 anos, tempo médio de hemodiálise de 28,523 meses. Utilizou como instrumentos de coleta de dados o questionário genérico de qualidade de vida SF-36 e a entrevista semi-estruturada. Os dados foram submetidos a análise estatística descritiva, o teste qui-quadrado, o coeficiente de correlação de Pearson e o teste de comparação de proporções, efetuados ao nível de 5% de significância. Os resultados constataram prejuízo na qualidade de vida dos pacientes, demostrando menores escores nos domínios dos aspectos fisicos (32 3+11 3), aspectos emocionais (46,11 6,3) e vitalidade (48,77,3). As variáveis de qualidade de vida em relação ao sexo não apresentou diferença significante. Verificou-se correlação negativa entre tempo de hemodiálise e componente físico (r = -0,75, p< 0,001), indicando que quanto maior o tempo de hemodiálise mais baixos são os valores encontrados deste componente e não houve correlação sígnificante entre tempo de hemodiálise e componente mental (r = -0,29). As atividades corporais e recreativas foram as mais comprometidas tanto na amostra global quanto na estratificada por sexo. Observou-se correlação negativa entre tempo de hemodiálise e as atividades cotidianas: trabalho (p=0,001 4), atividades domésticas (p= 0,0014) e atividades práticas (0,0459). Nota de Resumo Os dados evidenciaram o comprometimento em vários domíníos analisados da qualidade de vida dos renais crônicos em hemodiálise e identificaram que as atividades cotidianas corporais e recreativas foram as mais afetadas. Os resultados permitiram concluir: que não houve evidências de diferença estatisticamente significantes da qualidade de vida em relação ao sexo; houve diferença estatisticamente significante quanto as atividades cotidianas; o tempo de hemodiálise correlacionado com a qualidade de vida e atividades cotidianas apresentou correlação negativa no componente físico e nas atividades do trabalho, domestica e prática respectivamente Estes valores são importantes fatores preditivos para a melhora dos parâmetros de qualidade de vida destes pacientes.

Les taux de production du nucléide cosmogénique 36Cl par spallation du Ca et du K (SLHL) proposés actuellement dans la littérature montrent des divergences allant jusqu'à 50% (Gosse and Phillips, 2001). Nous avons pu montrer que des fortes teneurs en Cl dans les roches utilisées pour les calibrations précédentes entraînent une surestimation de ces taux de production, lié à la production de 36Cl à partir du 35Cl qui est peu contrainte. Nous avons entrepris une nouvelle calibration à partir de laves datées indépendamment entre 0.4 et 32 ka situées au Mt. Etna (38°N, Italie) et au Payun Matru (36°S, Argentine). Le 36Cl a été mesuré dans des feldspaths riches en Ca et en K, mais faibles en Cl. A partir d'une approche bayesienne incluant toutes les incertitudes, les taux de production obtenus sont de 42.2 ± 4.8 atomes 36Cl (g Ca)-1 an-1 pour la spallation du Ca et de 124.9 ± 8.1 atomes 36Cl (g K)-1 an-1 pour la spallation du K, avec les facteurs d'échelle calculés selon Stone (2000). Quatre autres modèles de facteurs d'échelle sont également proposés avec des résultats très semblables. Ces nouveaux taux de production sont en accord avec les valeurs précédemment obtenues par d'autres auteurs avec des échantillons faibles en Cl. Finalement, les concentrations en 36Cl, 3He et 21Ne ont été mesurées dans des pyroxènes prélevés entre 1000 et 4300 m dans des laves du Kilimandjaro (3°S). Les rapports entre ces nucléides ne montrent pas de dépendance altitudinale, ce qui suggère que les taux de production ne varient pas d'un nucléide à l'autre avec l'altitude.

<p><strong>Problemformulering </strong>Svenska företag som från år 2005 redovisar enligt IAS/IFRS ska i högre utsträckning än tidigare fördela det överpris som betalas vid företagsförvärv på de tillgångar som förvärvas. Tidigare studier har efter införandet mätt var tillgångarna tar vägen vid rörelseförvärv. Det har visat sig svårt för företagen att på ett konsekvent och stringent sätt identifiera immateriella tillgångar sedan specificera dem tydligt i balansräkningen. Begreppsförvirring och otydliga poster i redovisningen har gjort de svårt för användaren av årsredovisningen att få relevant information. Frågan är om det blivit bättre med tiden?</p><p><strong>Syfte </strong>Mäta utvecklingen av specificerade immateriella tillgångar sedan införandet av IAS/IFRS. Följande frågeställningar har ställts: 1. Specificerar företag sina identifierade immateriella tillgångar enligt de ramverk IASB förespråkar så att god redovisningssed kan återspeglas? 2. Har andelen ospecificerade immateriella tillgångar minskat?</p><p><strong>Metod </strong>För att samla in information om utvecklingen har vi studerat årsredovisningen för svenska noterade börsföretag som redovisar enligt IAS/IFRS. Årsredovisningar mellan åren 2003 och 2008 för bolag på stockholmsbörsens Large cap-lista har studerats. En kvantitativ undersökning där operationalisering används för att koda poster från balansräkningen. Egen kodning av vad som anses som vara tillräcklig specificering av tillgången har utförts med begreppet god redovisningssed som grund. Slutligen genomförs beräkning på antal, andel och värde av specificerade immateriella tillgångar varje år.</p><p><strong>Teoretisk referensram </strong>De normer, praxis och lagar som berör immateriella tillgångar och företagsförvärv har författarna sammanställt för att kunna ta del av informationen från årsredovisningar och definiera egna begrepp, Immateriella tillgångar (IAS 38), Företagsförvärv (IFRS 3), Nedskrivning (IAS 36) och redovisningens egenskaper återkopplas i slutsatsen.</p><p><strong>Slutsats </strong>Efter våra kriterier för ospecificerade poster fick vi fram att en positiv utveckling har skett sedan införandet av IAS/IFRS. I takt med identifiering av immateriella tillgångar ökar specificering. Ospecificerade poster har sjunkit med drygt 10 %. Värdet av immateriella har under studiens tidsperiod ökat med 1303 %. Det har inneburit att det totala värdet av ospecificerade tillgångar idag är betydligt större. Det i sin tur påverkar givetvis användaren när den ska ställning till en betydligt större summa ospecificerade tillgångar.</p> / <p><strong>Problem </strong>Listed companies have since the introduction of IAS / IFRS new accounting directives to follow. A major difference is that goodwill, as an asset, may no longer be amortized but will be subjected to an annual impairment test. This will result in the extraction, identification and depreciation of intangible assets from goodwill. This has been proved difficult for companies to identify consistently and rigorously. Confusion and vague items in reporting has made it difficult for users to share information in a proper way.</p><p><strong>Purpose </strong>To measure the progress of specified intangible assets in annual reports, since the introduction of IAS / IFRS. Questions to be answered: 1. Do companies specify their identified intangible assets in agreement with the IASB framework? 2. Has the total value of unspecified assets decreased over time?</p><p><strong>Method </strong>To gather information, we have studied the annual reports of listed companies reporting under IAS / IFRS. For this report, we have chosen annual reports from the years 2003 to 2008 on companies on the Stockholm Stock Exchange's Large Cap list and made a quantitative study, in which operationalization is used to encode the items from the balance sheet.</p><p><strong>Theoretical frame of reference </strong>We have compiled the standards, practices and laws relating to intangible assets and acquisitions. This has been done to acquire the information from annual reports and to define our own concepts. Intangible assets (IAS 38), Business Combinations (IFRS 3), Impairment (IAS 36) and accounting characteristics serve as a foundation to our conclusions.</p><p><strong>Conclusion </strong>Following our criteria for unspecified items, a positive development has occurred since the introduction of IAS / IFRS. As the identification of intangible assets develops with IFRS3 we have seen an increase of specification. Unspecified items have decreased by over 10%. The value of intangible assets during this period has increased by 1303%. It has meant that the total value of unspecified assets today is much bigger. This will affect the user, of course, when he/she will consider a much larger amount unspecified assets.</p>

L’ostéopathie fonctionnelle est connue pour son action mécanique de rééquilibration des différentes structures du corps, action qui vient en renfort d’un processus permanent d’autoréparation de l’organisme. « Retracer la lésion sans irriter » dénoue les tensions myofasciales et produit des effets psychiques moins connus mais capitaux dans la clinique des troubles post-traumatiques. La prise en charge par ostéopathie fonctionnelle de patients « tout-venants » d’un cabinet privé a servi de pré-recherche qualitative pour repérer les mécanismes psychiques à l’œuvre. Puis la recherche quantitative AIVIO (Aide Intensive aux Victimes par Ostéopathie) a permis une prise en charge prospective randomisée sur plusieurs thérapeutes de victimes d’accident de la voie publique (AVP) recrutées dans un hôpital sur critère d’Etat de Stress Post-traumatique (ESPT) et/ou douleur. Cette recherche a montré l’efficacité d’une telle prise en charge par des résultats cliniques satisfaisants et statistiquement significatifs selon divers questionnaires (MOS SF-36, PCLS, DES, PPAG, BECK 21) Les résultats hautement significatifs concernent la douleur, la vie sociale et la santé psychique pour les victimes d’AVP. La taille des cohortes n’a pas permis de conclure sur l’impact du point de vue biologique, notamment sur l’évolution des taux bas de cortisol, pathognomoniques d’ESPT. L’évolution psychosomatique des patients, montrant trois différents destins, confortent les hypothèses de départ : 1/ Certains troubles anxieux post-traumatiques pourraient être soulagés par le soin du corps lui-même. Eliminer le whiplash et autres tensions myofasciales semble parfois réguler l’irritation neurovégétative et les troubles anxieux. 2/ Le cadre du soin ostéopathique produirait, en plus du travail somatique, un retour tridimensionnel (lieu-temps-niveau de conscience) sur la mémoire épisodique du traumatisme et ses affects liés. La part psychique du traumatisme s’éliminerait par réminiscence du traumatisme dans un état dissociatif paisible ou pendant un moment de sommeil. En cas de résistance au relâchement myofascial, induire délicatement ce processus habituellement spontané et inconscient relancerait le processus d’autoréparation psychique et somatique. L’induction ne parviendrait pourtant pas à diminuer les résistances lorsqu’elles reposent sur la colère, l’angoisse d’origine infantile et sur des difficultés affectives ou socio-économiques majeures. 3/ Dans d’autres cas enfin, le traumatisme corporel donnerait une occasion et un support somatique pour exprimer d’autres souffrances psychonévrotiques. Le symptôme douloureux post-traumatique serait alors maintenu par tension myofasciale. L’écoute active serait parfois suffisante pour libérer cette souffrance somatisée, surtout quand on connaît les mécanismes de défense spécifiques des différentes personnalités psychonévrotiques. Sinon l’approche psychothérapeutique conjointe serait conseillée en cas de névrose plus marquée ou de décompensation d’assises narcissiques fragiles. Du point de vue psychosomatique, nous n’avons pas observé de pensée opératoire ni de refoulement de l’imaginaire. Le symptôme étant déterminé par conservation d’énergie mécanique du traumatisme, il n’est pas métaphorique et ne devrait donc pas être interprété.

Problemformulering Svenska företag som från år 2005 redovisar enligt IAS/IFRS ska i högre utsträckning än tidigare fördela det överpris som betalas vid företagsförvärv på de tillgångar som förvärvas. Tidigare studier har efter införandet mätt var tillgångarna tar vägen vid rörelseförvärv. Det har visat sig svårt för företagen att på ett konsekvent och stringent sätt identifiera immateriella tillgångar sedan specificera dem tydligt i balansräkningen. Begreppsförvirring och otydliga poster i redovisningen har gjort de svårt för användaren av årsredovisningen att få relevant information. Frågan är om det blivit bättre med tiden? Syfte Mäta utvecklingen av specificerade immateriella tillgångar sedan införandet av IAS/IFRS. Följande frågeställningar har ställts: 1. Specificerar företag sina identifierade immateriella tillgångar enligt de ramverk IASB förespråkar så att god redovisningssed kan återspeglas? 2. Har andelen ospecificerade immateriella tillgångar minskat? Metod För att samla in information om utvecklingen har vi studerat årsredovisningen för svenska noterade börsföretag som redovisar enligt IAS/IFRS. Årsredovisningar mellan åren 2003 och 2008 för bolag på stockholmsbörsens Large cap-lista har studerats. En kvantitativ undersökning där operationalisering används för att koda poster från balansräkningen. Egen kodning av vad som anses som vara tillräcklig specificering av tillgången har utförts med begreppet god redovisningssed som grund. Slutligen genomförs beräkning på antal, andel och värde av specificerade immateriella tillgångar varje år. Teoretisk referensram De normer, praxis och lagar som berör immateriella tillgångar och företagsförvärv har författarna sammanställt för att kunna ta del av informationen från årsredovisningar och definiera egna begrepp, Immateriella tillgångar (IAS 38), Företagsförvärv (IFRS 3), Nedskrivning (IAS 36) och redovisningens egenskaper återkopplas i slutsatsen. Slutsats Efter våra kriterier för ospecificerade poster fick vi fram att en positiv utveckling har skett sedan införandet av IAS/IFRS. I takt med identifiering av immateriella tillgångar ökar specificering. Ospecificerade poster har sjunkit med drygt 10 %. Värdet av immateriella har under studiens tidsperiod ökat med 1303 %. Det har inneburit att det totala värdet av ospecificerade tillgångar idag är betydligt större. Det i sin tur påverkar givetvis användaren när den ska ställning till en betydligt större summa ospecificerade tillgångar. / Problem Listed companies have since the introduction of IAS / IFRS new accounting directives to follow. A major difference is that goodwill, as an asset, may no longer be amortized but will be subjected to an annual impairment test. This will result in the extraction, identification and depreciation of intangible assets from goodwill. This has been proved difficult for companies to identify consistently and rigorously. Confusion and vague items in reporting has made it difficult for users to share information in a proper way. Purpose To measure the progress of specified intangible assets in annual reports, since the introduction of IAS / IFRS. Questions to be answered: 1. Do companies specify their identified intangible assets in agreement with the IASB framework? 2. Has the total value of unspecified assets decreased over time? Method To gather information, we have studied the annual reports of listed companies reporting under IAS / IFRS. For this report, we have chosen annual reports from the years 2003 to 2008 on companies on the Stockholm Stock Exchange's Large Cap list and made a quantitative study, in which operationalization is used to encode the items from the balance sheet. Theoretical frame of reference We have compiled the standards, practices and laws relating to intangible assets and acquisitions. This has been done to acquire the information from annual reports and to define our own concepts. Intangible assets (IAS 38), Business Combinations (IFRS 3), Impairment (IAS 36) and accounting characteristics serve as a foundation to our conclusions. Conclusion Following our criteria for unspecified items, a positive development has occurred since the introduction of IAS / IFRS. As the identification of intangible assets develops with IFRS3 we have seen an increase of specification. Unspecified items have decreased by over 10%. The value of intangible assets during this period has increased by 1303%. It has meant that the total value of unspecified assets today is much bigger. This will affect the user, of course, when he/she will consider a much larger amount unspecified assets.

The objective of the International Financial Reporting Standards (IFRS) is to provide useful information to the users of financial statements to assist in making economic decisions. To be useful, information has to be relevant and reliable, but the reliability of information suffers when the guidelines for the reporting of specific issues are not clear and managerial discretion arises. Write-offs are one of those accounting issues that are regularly related to earnings management. By now it is seen as common knowledge that write-offs, especially those on goodwill, do not reflect declines in asset value; rather, they are used as a device to manipulate financial reports. However, there is a striking lack of grounded theoretical research that can confirm this assessment. The aim of this dissertation is to provide valuable analytical and empirical insights on fixed asset write-offs under IFRS. In a first step, the practical implementation of IAS 36 in Europe has to be analyzed, which is best done empirically. Based on the findings from these empirical surveys, the most substantial questions remaining are subject to an in-depth analytical discussion. Since IAS 36 entails different measurement issues that have their origins in finance theory, this dissertation also aims to introduce some basic techniques from theoretical finance to accounting research. Lastly, as the analyses presented in this dissertation do not cover all open questions on fixed asset write-offs, the author hopes to encourage further research on this important topic.

No description available.

Background Recently, Taiwan has been faced with the migration of numbers of women from Southeast Asian (SEA) countries. It was estimated that the aggregate number of SEA wives in Taiwan was more than 131,000 in 2007 (Ministry of Foreign Affairs, 2006).These women are often colloquially called, “foreign brides” or “alien brides”; most of them are seen as commodities of the marriage trade, whose marriages are arranged by marriage brokers. Some women can be regarded as being sold for profit by their families. These young Vietnamese immigrant women come to Taiwan alone, often with a single suitcase, and are culturally and geographically distinct from Taiwanese peoples; the changes in culture, interpersonal relationships, personal roles, language, value systems and attitudes exert many negative impacts on their health, so greater levels of acculturation stress can be expected. This particular group of immigrant women are highly susceptible and vulnerable to health problems, due to language barriers, cultural conflicts, social and interpersonal isolation, and lack of support systems. The aims of this study were to examine the relationships between acculturation and immigrantspecific distress and health outcomes among Vietnamese transnational married women in Taiwan. This study focuses on Vietnamese intermarriage immigrants, the largest immigrant group in the period from1994 through to 2007. Methodology The quantitative study was divided into two phases: the first was a pilot study and the second the main study. This study was conducted in a communitybased health centre in the south of Taiwan, targeting Taiwanese households with Vietnamese wives, including the Tanam, Kaohsiung, and Pentong areas. This involved convenience sampling with participants drawn from registration records at the Public Health Centre of Kaohsiung and used the snowball technique to recruit 213 participants. The instruments included the following measures: (1) Socio-demographic information (2) Acculturation Scale (3) Acculturative Distress Scale, and (4) HRQOL. Questions related to immigrant women’s acculturation level and health status were modified. Quantitative data was coded and entered into the SPSS and SAS program for statistical analysis. The data analysis process involved descriptive, bivariate, multivariate multiple regression, and classification and regression trees (CART). Results Six hypotheses of this study were validated. Demographic data was presented and it revealed that there are statically significant differences between levels of acculturation and years of residency in Taiwan, number of children, marital status, education, religion of spouse, employment status of spouse and Chinese ethnic background by Pearson correlation and Kendall’s Tau-b or Spearman test. The correlations of daily activity, language usage, social interaction, ethnic identity, and total of acculturation score with DI tend to be negatively significant. In addition, the result of the one-way ANOVA supported the hypothesis that the different types of acculturation had a differential effect on immigrant distress. The marginalized group showed a greater immigrant distresses in comparison with the integrated group. Furthermore, the comparison t-test revealed that the Vietnamese immigrant women showed a lower score than Taiwanese women in HRQOL. The result showed higher acculturative stress associated with lower score of HRQOL on bodily pain, vitality, social functioning, mental health, and mental component summary. The CART procedure to the conclusion that the predictive variables for the physical component of the SF-36 (PCS) were: alienation, occupation, loss, language, and discrimination (predicted 28.8% of the total variance explained). The predictive variables for the mental component of the SF-36 (MCS) were: alienation, occupation, loss, language, and novelty (predicted 28.4% of the total variance explained). Conclusion As these Vietnamese immigrant women become part of Taiwanese communities and society, the need becomes apparent to understand how they acculturate to Taiwan and to the health status they acquire. The findings have implications for nursing practice, research, and will assist the Taiwanese government to formulate appropriate immigrant health policies for these SEA immigrant women. Finally, the application of this research will positively contribute to the health and well being of thousands of immigrant women and their families.

The goal of diploma thesis was a comparison of potable water indicators in representative areas of the south Bohemia. Monitored period had been from January 2012 till December 2014. Monitored parameters were microbiological indicators (Escherichia coli, coliform microbes, number of colonies at 22°C, number of colonies at 36°C, organoleptic indicators (color, turbidity, smell, taste). Physical and chemical indicators (ammonium ions, nitrates, nitrites, chemical consumption of oxygen, chlorides, conductivity, manganese, pH, sulphates, calcium and magnesium, iron). From the total complex of 1165 data, there were 23 values over the limit (1,97%) of evaluation of all monitored quality indicators (microbiological, organoleptic, physical and chemical). In evaluation of microbiological indicators, there were 6 values (1,97%) over the limit, from total 304 data. In organoleptic indicators, there was 1 value (0,44%) over the limit, from total 227 data. In evaluation of physical and chemical indicators, there were 16 values (2,52%) over the limit, from total 634 data. In total, there are 23 values which don´t meet determined limits from The Regulation No. 252/2004 and EU directives. There are these values of limits - number of colonies at 22°C, number of colonies at 36°C, turbidity, manganese, calcium and iron.