INTRODUÇÃO: As intervenções de promoção da saúde mental avançam e atividades não medicamentosas ganham espaço. Neste sentido, estudos apontam a atenção plena (mindfulness) como estratégia integrativa para o enfrentamento do estresse e de transtornos mentais comuns, bem como para obtenção do autocuidado. Mindfulness é referido no contexto laico contemporâneo como um estado mental presente em todos os indivíduos em maior ou menor intensidade que pode ser cultivado diariamente através de práticas meditativas. OBJETIVO: Descrever o nível da autopercepção de comportamentos relacionados à Mindfulness em profissionais da saúde de um Hospital Terciário e analisar a associação dos níveis de mindfulness autopercebidos com determinados indicadores das condições de vida e saúde. MÉTODO: Foi realizado um estudo transversal com 97 profissionais da saúde que compõem o complexo do Hospital das Clínicas - FMUSP por via de caracterização Sociodemográfica, da Escala Filadélfia de Mindfulness (EFM) e de um Questionário de Saúde Geral (General Health Questionnaire -12). Todos os questionários foram aplicados no período de fevereiro/novembro de 2014. RESULTADO: Na EFM, o escore médio apresentado foi maior para o componente \"Consciência\" (média 29,9; desviopadrão 0,62) do que para \"Aceitação\" (média 15,7; desvio-padrão 0,86), sendo a média 45,6 e desvio-padrão 1,1 para o Escore Total (componente \"consciência\" somada a \"aceitação\"); Verificou-se número significativo de indivíduos (41%) com suspeita de transtornos mentais comuns (TMC), aqueles que apresentaram um escore de três ou mais no GHQ-12. Em análise mais detalhada (Teste t e ANOVA) observou-se associações fortemente significantes (p < 0,01) entre maiores níveis de mindfulness autopercebido com o gênero masculino, estado civil casado/amigado, maior satisfação no trabalho, negar uso de medicamentos, sono satisfatório, lazer frequente e ausência de TMC. Na análise da associação GHQ-12 com Mindfulness estratificada por profissão verificou-se escores menores no grupo das categorias \"psicólogo, assistente social, profissional de educação física, biólogo, fisioterapeuta, farmacêutico e profissional administrativo\" com TMC; na análise da associação GHQ-12 com Mindfulness estratificada por tipo de doença concluiu-se que existem diferenças significantes (p < 0,01) no grupo das categorias \"mais de uma doença, neurológica ou psiquiátrica\", das quais o escore \"Total\" e \"Aceitação\" foram menores para quem apresenta TMC. A presença de TMC (referido pelo GHQ-12) está associada a menores escores de Mindfulness, indicando uma possível correlação negativa que se deve ao domínio de \"Aceitação\" CONCLUSÃO: Os níveis de comportamentos autopercebidos à atenção plena apontaram associações significantes com uma variedade de indicadores das condições de vida e saúde nos profissionais de saúde. Sugerindo assim, uma mesma direção de evidências científicas recentes de que mindfulness pode fazer parte de fatores de proteção à saúde favorecendo também o autocuidado e a qualidade de vida / INTRODUCTION: The Mental Health Promotion interventions advance and non-drug activities gain ground. In this case, studies show meditation as an opportunity to cope with stress and the common mental disorders, as well as to obtain self-care. Mindfulness is referred in contemporary laic context as a present mental state in all individuals in greater or lesser degree which can be daily cultivated through meditative practices. OBJECTIVE: This study aimed to describe the self-perceived level of Mindfulness-related behaviors in health care professionals of a tertiary care hospital as well as to analyze the association of self-perceived mindfulness levels with certain indicators of living conditions and health. METHOD: A cross-sectional study is proposed with 97 health professionals who make up the University Hospital complex - FMUSP via Socio Demographic characterization, a study of the Philadelphia Mindfulness Scale (PMS) and a Questionnaire of General Health (General Health Questionnaire -12). All interviews were conducted between February and November/ 2014. RESULT: In PMS, the average score was higher for the component \"awareness\" (mean 29.9, SD 0.62) than for \"acceptance\" (mean 15.7, SD 0.86), with an average 45.6 and SD 1.1 for the Total Score (component \"awareness\" added to \"acceptance\"); There was a significant number of individuals (41%) with suspected common mental disorders (CMD), those with a score of three or higher in the GHQ-12. In a more detailed analysis (T-Test and ANOVA) it was observed strongly significant associations (p < 0.01) with higher levels of self-perceived mindfulness in the masculine gender, married / living together unmarried, greater job satisfaction, not in use of medicinal drugs, satisfactory sleep, frequent leisure and no presence of CMD. In the analysis of the GHQ-12 association with Mindfulness stratified by profession it was observed that the scores were lower for the group of the categories \"psychologist, social worker, physical education professional, biologist, physiotherapist, pharmacist and administrative professional\" with CMD; in the analysis of the GHQ-12 association with Mindfulness stratified by disease type the results showed that there are significant differences (p < 0.01) for the group of the categories \"more than one disease, either neurological or psychiatric\", of which the score \"Total\" and \"Acceptance\" were lower for those who had CMD. The presence of CMD (referred by the GHQ-12) is associated with lower scores of Mindfulness, indicating a possible negative correlation due to the domain of \"Acceptance\". CONCLUSION: The levels of self-perceived behaviors to mindfulness showed significant associations with a variety of indicators of living conditions and health among health care professionals. Suggesting, thus, the same direction of recent scientific evidences that mindfulness may be part of health protective factors also favoring self-care and quality of life

The collection and utilisation of statistical data is an integral component of rendering primary health care services. This study aimed to assess the utilisation of statistics on certain statistical forms submitted regularly to the Department of Health, by professional nurses at local authority primary health care clinics. Results revealed the following important shortcomings: • Statistics on different forms are viewed in isolation, resulting in a lack of necessary comparisons being made to determine trends. • Several targeted issues in the Reconstruction and Development Programme received insufficient attention, for example, immunisations, teenage pregnancies, tuberculosis treatment, sexually transmitted diseases. • A general managerial inability to analyse, display and utilise collected data by professional nurses. Recommendations centred around increasing the knowledge regarding maternal health care, more focus on prioritised areas of the Reconstruction and Development Programme, appropriate training regarding analysis and utilisation of collected statistics at local primary health care level. / Health Studies / M.A. (Nursing)

The collection and utilisation of statistical data is an integral component of rendering primary health care services. This study aimed to assess the utilisation of statistics on certain statistical forms submitted regularly to the Department of Health, by professional nurses at local authority primary health care clinics. Results revealed the following important shortcomings: • Statistics on different forms are viewed in isolation, resulting in a lack of necessary comparisons being made to determine trends. • Several targeted issues in the Reconstruction and Development Programme received insufficient attention, for example, immunisations, teenage pregnancies, tuberculosis treatment, sexually transmitted diseases. • A general managerial inability to analyse, display and utilise collected data by professional nurses. Recommendations centred around increasing the knowledge regarding maternal health care, more focus on prioritised areas of the Reconstruction and Development Programme, appropriate training regarding analysis and utilisation of collected statistics at local primary health care level. / Health Studies / M.A. (Nursing)

<p>Cilj: Utvrditi funkcionalni i mentalni status pacijenata pre i posle medicinske rehabilitacije, a nakon operacije kuka kod osoba starije životne dobi primenom standardizovanih upitnika (SF36, Harris hip score, MMS, TUG, FES-I) . Materijal i metod:Istraživanje je bilo prospektivno i uzorak je činilo 96 pacijenata sa prethodnom operacijom kuka koji su u toku 18 meseci, od januara 2014., bili u rehabilitacionom programu na Klinici za medicinsku rehabilitaciju KCV. Kod svih pacijenata je registrovan: pol i starosna dob, kao i uzrok odnosno vrsta operativnog zahvata. Pacijenti su pregledani i anketirani sa svih 5 upitnika u tri vremenska trenutka: pre samog početka rehabilitacionog tretmana i na 3 i 6 meseci posle. SF-36 je generički merni obrazac koji se koristi za procenu kvaliteta života. Harris Hip Score (HHS) predstavlja merni instrument za procenu funkcionalnih parametara. Mini Mental State (MMS) se koristi kod procene mentalnog statusa. Timed Up and Go Test (TUG) je efikasan metod procene pokretljivosti i funkcije lokomotornog sistema kod starijih pacijenata. Falls Efficacy Scale- International (FES-I) je test kojim se meri stepen zabrinutosti od pada. Metodom ponovljenih merenja analizirana su stanja pacijenata pre i posle medicinske rehabilitacije. Izvr&scaron;ena je i korelaciona analiza kori&scaron;ćenih upitnika, kao i univarijantna analiza u odnosu na vrstu operacije. Rezultati:Nakon medicinske rehabilitacije posle operacije kuka kod osoba starije životne dobi je značajno bolji ukupni fizički skor SF36: 29,0 / 38,7 / 46,3; kao i vrednost HHS skora 50,2 / 63,4 / 76,3; i TUG testa 31,3s / 19,6s / 13,6s; (pre rehabilitacije, 3m i 6m respektivno). Postoje statistički značajne korelacije ukupnog fizičkog domena SF36 i vrednosti Harris Hip, TUG i FES-I, kao i ukupnog mentalnog domena SF36 i MMS skora. Zadovoljstvo pacijenata rehablitacionim tretmanom je u korelaciji sa vrednostima funkcionalnih testova (Harris Hip Score), testom ustani kreni (TUG) i ukupnim fizičkim domenom upitnika SF36, kao i sa skorom FES-I. Zaključci: Kvalitet života i funkcionalna sposobnost operisanih pacijenata nakon medicinske rehabilitacije je značajno bolja kako u komparaciji stanja na tri meseca i na početku rehabilitacije tako i u komparaciji stanja na 6 meseci u odnosu na stanje na 3 meseca.</p> / <p>Objective: To determine the functional and mental status of patients before and after medical rehabilitation after hip surgery in elderly by using standardized questionnaires (SF36, Harris hip score, MMS, TUG, FES-I). Materials and methods:The study was prospective and the sample consisted of 96 patients with previous hip surgery that during the 18 months from January 2014, was in a rehabilitation program at the Department of medical rehabilitation KCV. For all patients registered sex and age, as well as the cause and type of surgery.Patients are screened and interviewed with all 5 of the questionnaire in three time points: before the start of the rehabilitation treatment and at 3 and 6 months after. SF-36 is a generic form that measurement is used to assess the quality of life. Harris Hip Score (HHS) is a measuring instrument for the assessment of functional parameters. Mini Mental State (MMS) used in the assessment of mental status. Timed Up and Go Test (TUG) is an effective method of evaluating the mobility and function of the musculoskeletal system in older patients.Falls Efficacy Scale- International (FES-I) is a test that measures the level of concern of falling. Method of repeated measurements were used to analyse condition of patients before and after medical rehabilitation. There was also a correlation analysis of used questionnaires, as well as the univariate analysis in relation to the type of surgery. Results: After medical rehabilitation after surgery of the hip in the elderly is significantly better overall physical SF36 score: 29.0 / 38.7 / 46.3; as well as the value of the HHS score of 50.2 / 63.4 / 76.3; and the TUG test 31,3s / 19,6s / 13,6s; (before rehabilitation, 3m and 6m respectively). There are statistically significant correlations of total physical domain SF36 and values Harris Hip, TUG and the FES-I, and the overall mental domain of SF36 and MMS score. Patient satisfaction with rehabilitation treatment is correlated with the values of functional tests (Harris Hip Score) test Up and go (TUG) and total physical domain SF36 questionnaires, as well as the FES-I. Conclusion: Quality of life and functional capacity of treated patients after medical rehabilitation significantly improved both in comparison to the situation in three months and at the beginning of rehabilitation as well as in comparison at 6 months compared to 3 months.</p>

<p>Oralno zdravlje predstavlja stanje zdravlja svih anatomskih i funkcionalnih delova usne duplje, jedan je od osnovnih elemenata blagostanja i važan pokazatelj kvaliteta života stanovni&scaron;tva. Podaci Svetske zdravstvene organizacije (SZO) ukazuju da je 15-20% svetskog stanovni&scaron;tva srednje životne dobi (starosti od 35 do 44 godine) pod rizikom od gubitka zuba, a oko 30% stanovni&scaron;tva starosti od 65 do 74 godine nema svoje zube. Oboljenja usta i zuba su jedan od vodećih javno zdravstvenih problema 21. veka u svetu i nalaze se na 4. mestu po visini tro&scaron;kova. Osnovni cilj ovog istraživanja je bio da se utvrdi stanje oralnog zdravlja odraslog stanovni&scaron;tva Srbije starosne dobi 20 i vi&scaron;e godina i evaluiraju činioci koji na njega utiču. Istraživanje predstavlja deo nacionalne studije &ldquo;Istraživanje zdravlja stanovnika Srbije&rdquo; za 2013. godinu Ministarstva zdravlja Republike Srbije, koja je sprovedena u vidu studije preseka na reprezentativnom uzorku od 13690 ispitanika (53,8% žene i 46,2% mu&scaron;karci). U istraživanju su kori&scaron;ćene tri vrste upitnika koji su dizajnirani u skladu sa upitnikom Evropskog istraživanja zdravlja. Svaki ispitanik stariji za jednu godinu ima 8% veću &scaron;ansu da svoje oralno zdravlje oceni kao lo&scaron;e (OR=1.08; 95% IP=(1.07-1.09); p=0,000). Ispitanici sa blagim depresivnim simptomima i depresivnim poremećajima imaju 2,04 odnosno 3,48 puta veću &scaron;ansu da svoje oralno zdravlje ocene kao lo&scaron;e u odnosu na ispitanike koji nisu depresivni (OR=2.04; 95% IP=(1.28-3.26); p=0,003) (OR=3.48; 95% IP=(1.14-10.59); p=0,028). Žene imaju 30% veću &scaron;ansu da pripadnu povoljnoj kategoriji poseta stomatologu u odnosu na mu&scaron;karce (OR=0.70; 95% IP=(0.63-0.78); p=0,000). Ispitanici sa nižim i srednjim obrazovanjem imaju 5,70 odnosno 2,45 puta veću &scaron;ansu da svoje zube operu povremeno u odnosu na visoko obrazovane (OR=5.70; 95% IP=(4.35-7.48); p=0,000) (OR=2.45; 95% IP=(1.91-3.13); p=0,000). Ispitanici najsiroma&scaron;nijeg sloja imaju 4,88, siroma&scaron;nog sloja 3,73, srednjeg sloja 2,52 i bogatog sloja 2,01 put veću &scaron;ansu da izgube 10 i vi&scaron;e zuba u odnosu na najbogatiji sloj (OR=4.88; 95% IP=(2.95-8.08); p=0,000) (OR=3.73; 95% IP=(2.42-5.75); p=0,000) (OR=2.52; 95% IP=(1.69-3.76); p=0.000) (OR=2.01; 95% IP=(1.38-2.91); p=0,000). Biv&scaron;i pu&scaron;ači i pu&scaron;ači imaju 1,43 odnosno 2,80 puta veću &scaron;ansu da izgube 10 i vi&scaron;e zuba u odnosu na nepu&scaron;ače (OR=1.43; 95% IP=(1.00-2.03); p=0,046) (OR=2.80; 95% IP=(2.08-3.76); p=0,000). Najučestaliji prediktori oralnog zdravlja su žene, starije stanovni&scaron;tvo, niže obrazovanje, nezaposleno i neaktivno stanovni&scaron;tvo, najsiroma&scaron;niji i pu&scaron;ači.</p> / <p>Oral health represents health status of all anatomic and functional parts of oral cavity, it is one of the basic elements of well-being and important quality of life indicator. According to the World Health Organization (WHO) 15-20% of world population aged 35-44 have risk of tooth loss, and about 30% population aged 65-74 does not have own teeth. Oral and dental diseases are one of the leading public health problems in 21st century and on the 4th place of the health care expenditure. The main aim of this research was to assess oral health of adult population in Serbia aged 20 years and older and to evaluate related factors. The research represents a part of &ldquo;National Health Survey in Serbia 2013&rdquo; implemented by The Ministry of Health of the Republic of Serbia, which was conducted as a cross-sectional study on the representative sample of adult population in Serbia. The study included 13690 examinees (53.8% females and 46.2% males). Three types of questionnaires which were designed according to the European Health Interview Survey were used. Every examinee older for one year had 8% greater odds to assess their oral health as bed (OR=1.08; 95% CI=(1.07-1.09); p=0.000). Respondents with mild depressive symptoms and depressive disorders had 2.04 and 3.48 times greater odds to assess their oral health as bed compared to one who were not depressed (OR=2.04; 95% CI=(1.28-3.26); p=0.003) (OR=3.48; 95% CI=(1.14-10.59); p=0.028). Females had 30% more odds to be in the category of affordable dental visit compared to men (OR=0.70; 95% CI=(0.63-0.78); p=0.000). Respondents with lower and middle level of education had 5.70 and 2.45 greater odds to brush their teeth occasionally compared to higher educated (OR=5.70; 95% CI=(4.35-7.48); p=0.000) (OR=2.45; 95% CI=(1.91-3.13); p=0.000). Respondents who belonged to the poorest class had 4.88, poorer 3.73, middle 2.52 and richer class 2.01 greater odds to lose 10 and more teeth compared to the richest (OR=4.88; 95% CI=(2.95-8.08); p=0.000) (OR=3.73; 95% CI=(2.42-5.75); p=0.000) (OR=2.52; 95% CI=(1.69-3.76); p=0.000) (OR=2.01; 95% CI=(1.38-2.91); p=0.000). Former smokers and smokers had 1.43 and 2.80 times greater odds to lose 10 and more teeth compared with non smokers (OR=1.43; 95% CI=(1.00-2.03); p=0.046) (OR=2.80; 95% CI=(2.08-3.76); p=0.000). The most frequent predictors of oral health are: women, elderly people, those with low educational attainment, unemployed, inactive and respondents who assessed their financial situation as poor and smokers.</p>

<p>Depresija je jedan od najče&scaron;ćih mentalnih poremećaja u op&scaron;toj populaciji &scaron;irom sveta i prema podacima Svetske zdravstvene organizacije se nalazi na trećem mestu globalnog opterećenja bolestima. Cilj ovog istraživanja je bio da se utvrdi prevalencija depresije u populaciji odraslog stanovni&scaron;tva Vojvodine, da se identifikuju kategorije stanovni&scaron;tva pod najvećim rizikom i da se utvrdi povezanost depresije sa determinantama zdravlja, zdravstvenim stanjem i kori&scaron;ćenjem zdravstvene za&scaron;tite. Istraživanje je sprovedeno kao studija preseka na reprezentativnom uzorku stanovni&scaron;tva Vojvodine starosti 15 i vi&scaron;e godina, kao deo nacionalne studije &bdquo;Istraživanje zdravlja stanovni&scaron;tva Srbije&ldquo; koju je sprovelo Ministarstvo zdravlja Republike Srbije 2013. godine. Kao instrument istraživanja su kori&scaron;ćeni upitnici konstruisani u skladu sa upitnikom Evropskog istraživanja zdravlja. Prisustvo depresivnih simptoma je analizirano primenom PHQ-8 upitnika (Patient Health Questionnaire-8) a vrednost PHQ-8 skora 10 i vi&scaron;e je ukazivala na prisustvo depresivne epizode (depresije). Istraživanjem je obuhvaćeno 3550 ispitanika prosečne starosti 50,2 godine. Prevalencija depresije je iznosila 4,8%. Primenom multivarijantne regresije je utvrđeno da žene imaju za 40% veću &scaron;ansu za depresiju u odnosu na mu&scaron;karce (OR=1,4), a kao prediktori depresije su se pokazali i starija životna dob, razvod/razlaz ili udovstvo, niži nivo obrazovanja, nezaposlenost, ekonomska neaktivnost i niži materijalni status. Osobe koje su u mesecu koji je prethodio istraživanju bile izložene stresu su imale oko sedam puta veću &scaron;ansu za depresiju (OR=6,8), a kod ispitanika sa lo&scaron;om socijalnom podr&scaron;kom &scaron;ansa za depresiju je bila oko četiri puta veća nego kod ispitanika sa jakom socijalnom podr&scaron;kom (OR=3,7). Multimorbiditet je bio značajno prisutniji među ispitanicima sa depresijom, a &scaron;ansa za prisustvo dve ili vi&scaron;e hroničnih bolesti je kod njih bila skoro pet puta veća (OR=4,6) u odnosu na ispitanike koji nisu imali depresivne simptome. Depresija se pokazala i kao značajan prediktor če&scaron;ćeg kori&scaron;ćenja usluga zdravstvene za&scaron;tite. Dobijeni rezultati su potvrdili javnozdravstveni značaj depresije i istovremeno obezbedili podatke koji se mogu koristiti kao osnova za buduća prospektivna istraživanja, kao i za kreiranje programa za prevenciju i kontrolu depresivnih poremećaja i unapređenje mentalnog zdravlja.</p> / <p>Depression is one of the most common mental disorders in the general population worldwide and according to the World Health Organization it is the third leading cause of the global burden of disease. The aim of this study was to determine the prevalence of depression in the adult population of Vojvodina, to identify groups at the greatest risk of depression and to determine the relationship of depression with health determinants, health status and use of health care services. The research was carried out as a cross-sectional study on a representative sample of the population of Vojvodina, aged 15 and over as part of the National Health Survey of Serbia which was conducted by the Ministry of Health of the Republic of Serbia in 2013. Data was gathered by using questionnaires designed in accordance to the European Health Interview Survey. The presence of depressive symptoms was analyzed using the PHQ-8 questionnaire (Patient Health Questionnaire-8) and the score of 10 or above indicated a presence of a depressive episode (depression). The study included 3550 examinees with an average age of 50.2 years. The prevalence of depression was 4.8%. Multivariate regression showed that women had a 40% greater chance to suffer from depression as compared to men (OR=1.4). Also, factors such as older age, divorce/separation or widowhood, lower level of education, economic inactivity and poor financial situation were predictors of depression. People who were exposed to stress in the month prior to the survey had about seven times greater odds of depression (OR=6.8), and in patients with poor social support the chance of depression was about four times higher than among those with a strong social support (OR=3.7). Multimorbidity was significantly more prevalent among respondents with depression and they had five times higher odds of the presence of two or more chronic diseases (OR=4.6) in comparison with those who did not show depressive symptoms. Depression has been revealed as a significant predictor of more frequent use of health care services. The results confirmed the importance of depression to public health and also provided the data that can be used as a basis for future prospective studies, as well as for the development of the programs for the prevention and control of depressive disorders and mental health improvement.</p>

Introdução: Conhecida desde os tempos de Hipócrates, a varicela é autolimitada e isenta de complicações na maioria dos casos, mas responde por absenteísmo escolar das crianças e laboral dos cuidadores, além de hospitalizações e óbitos em pacientes previamente hígidos. Após a incorporação da vacina varicela no calendário americano em 1995, diversos países têm verificado suas epidemiologias para análise de custo-benefício da vacinação; alguns já vêm publicando resultados do impacto da vacina. O Brasil incluiu a vacina no calendário vacinal para crianças de 15 meses em 2013 e vem avaliando o seu impacto. Objetivos: Aprimorar dados pré-vacinais num hospital universitário de atenção secundária, descrevendo atendimentos de Pronto-Socorro Infantil (PSI), hospitalizações e internações em unidade de terapia intensiva (UTI) por varicela; caracterizar o perfil etário, sazonalidade e diagnósticos das complicações da doença, além de analisar possíveis fatores de risco para internação e evolução grave. Metodologia: Estudo retrospectivo descritivo de crianças e adolescentes menores de 15 anos com varicela, no período entre janeiro de 2003 e dezembro de 2012. Relacionamos os resultados à população local para calcular taxas de incidência, hospitalização, internação em UTI e óbito relacionadas à doença. O registro informatizado do hospital forneceu a lista de pacientes com diagnóstico de varicela no atendimento de PSI ou na internação; prontuários foram consultados para coleta de dados que foram submetidos a análise em programas estatísticos. Resultados: Ocorreram 8520 atendimentos em PSI com varicela, 508 destes (6,0%) sendo hospitalizados, 36 destes últimos (7,1%) necessitando de UTI e 2 óbitos (0,4% dos internados), fornecendo as seguintes taxas médias anuais: 887,5 atendimentos, 52,9 hospitalizações, 3,8 internações em UTI e 0,21 óbitos para 100.000 habitantes até 15 anos. Crianças abaixo de 5 anos representaram 75% dos atendimentos, 92,3% das hospitalizações e 88,9% das internações em UTI. Lactentes entre 12 e 15 meses representaram 4,5% dos atendimentos, 6,5% das hospitalizações e 6,1% das internações em UTI. O segundo semestre do ano representou 89,4% dos atendimentos de PSI. Os menores de 5 anos atendidos no PSI tiveram 4,3 vezes maior chance de internação que os maiores de 5 anos, mas a idade não representou diferença no risco para necessidade de UTI. Infecções de pele e partes moles causaram 72,6% das hospitalizações, enquanto problemas respiratórios e neurológicos responderam por 20,1% e 1%, respectivamente. O motivo principal da indicação de UTI foi instabilidade hemodinâmica; 58,3% necessitaram de drogas vasoativas. Comparando os que necessitaram de UTI e os que não necessitaram, os primeiros apresentavam maior tempo de varicela à admissão, febre mais prolongada após internação, maior quantidade absoluta e relativa de neutrófilos e suas formas jovens, Proteína C reativa mais alta e plaquetas reduzidas nos exames admissionais. Conclusão: As taxas epidemiológicas verificadas neste estudo se mostraram dentro do descrito em literatura; as infecções secundárias de pele e partes moles na varicela, sem CID10 específico, prevalecem sobre complicações como pneumopatia, meningite e encefalite, que possuem descritores específicos, como causas de internação e dados de história e exames admissionais podem ajudar a apontar gravidade / Introduction: Known since Hippocrates times, varicella is self-limited and complication-free in most cases, but it responds to school and labor absenteeism of children and caregivers, as well as previously healthy patients hospitalizations and deaths. After varicella vaccine was recommended for routine use in United States in 1995, several countries reviewed their epidemiology for cost-benefit analysis of vaccination; some of then published vaccine impact results. Brazil included varicella vaccine in immunization routine for 15 months child in 2013 and has been appraising its impact. Objectives: Improve pre-vaccination data from secondary care university hospital describing pediatric urgent care (PUC) assessment, inpatient department and pediatric intensive care unit (PICU) hospitalizations; define age profile, seasonality and varicella complications diagnoses and analyze hospitalization and severe evolution possible risk factors. Methods: This report is aimed to retrospectively discriminate children and adolescents under 15 years with varicella from January 2003 to December 2012. Local population was considered to propose varicella-related PUC visit, hospitalization, PICU stay and death rates. Hospital registration provided computerized varicella-diagnosed PUC assessment, inpatient and PICU patient list; data collected from its charts were submitted to statistical program analysis. Results: 8520 PUC varicella cases were reported, 508 of them (6.0%) were hospitalized, 36 of them (7.1%) required PICU and 2 died (0.4% of hospitalized patients), providing following annual rates: 887.5 assessments, 52.9 hospitalizations, 3.8 PICU admissions and 0.21 deaths per 100,000 inhabitants up to 15 years. Children younger than 5 years accounted for 75% of PUC visits, 92.3% of hospitalizations and 88.9% of PICU admissions. Infants between 12 and 15 months represented 4.5% of PUC visits, 6.5% of hospitalizations and 6.1% of PICU admissions. Second half of the year accounted 89.4% of PUC attendances. Under 5 years PUC child had 4.3 more hospitalization risk than those older than 5 years, but age did not represent difference in PICU risk. Skin and soft tissue infections caused 72.6% of hospitalizations, while respiratory and neurological problems accounted for 20.1% and 1%, respectively. The main reason for PICU indication was hemodynamic instability; 58.3% required vasoactive drugs. Comparing those who needed PICU and those who did not need them, the former had longer time of varicella on admission, longer fever after hospitalization, greater absolute and relative amount of neutrophils and their young forms, higher C-reactive protein levels and reduced platelets in admission exams. Conclusion: epidemiological rates verified in this study were within described in literature; secondary skin infections and soft tissues in varicella, without specific ICD-10, overcome complications as pneumopathy, meningitis, and encephalitis, which have specific descriptors; anamnesis and admission examinations data may help predict severity

O objetivo do estudo foi analisar a relação dos marcadores de desigualdade em saúde, com destaque para a posição socioeconômica, com a autoavaliação da saúde bucal e da saúde geral da população adulta brasileira em 2013. Estudaram-se 59.758 indivíduos com 18 anos ou mais de idade, que participaram da Pesquisa Nacional de Saúde 2013, um inquérito domiciliar de base populacional. As variáveis dependentes do estudo foram a autoavaliação da saúde bucal (dentes e gengivas) e autoavaliação da saúde geral, sendo ambas analisadas como positiva, regular e negativa. As variáveis independentes foram os marcadores de desigualdade em saúde (cor ou raça, região de residência, nível de escolaridade completo, renda domiciliar per capita e classe social). Odds ratios (OR) brutos e ajustados e intervalos de confiança de 95% (IC 95%) foram calculados usando modelos de regressão logística multinomial. Os resultados referentes à autoavaliação da saúde geral foram estratificados segundo o sexo. A prevalência da autoavaliação de saúde bucal positiva foi 67,4%, 26,7% para regular e 5,9% para negativa, enquanto para a saúde geral foram 66,2%, 28,0% e 5,8%, respectivamente. As mulheres avaliam pior sua saúde geral do que os homens. Após ajuste pelas variáveis de controle, as chances de autoavaliar a saúde bucal como negativa foi significativamente mais elevadas entre os indivíduos com renda domiciliar per capita de até um salário mínimo (OR=4,71; IC95%: 2,84-7,83), sem escolaridade (OR=3,28; IC95%: 2,34-4,61), da classe social destituídos de ativos (OR=3,03; IC95%: 2,12-4,32) e residentes da região nordeste (OR=1,50; IC95%: 1,19-1,89). Em relação à autoavaliação da saúde geral nos homens, as chances de avaliar pior foram significativamente mais elevadas entre os indivíduos de menor renda domiciliar per capita, com pior nível de escolaridade, pessoas fora da força de trabalho, moradores das regiões Nordeste e Norte e que se declararam pardos e pretos. Enquanto nas mulheres, as chances de avaliar pior seu estado de saúde geral foram maiores entre as de pior nível de escolaridade, menor renda domiciliar per capita, que se encontravam fora da força de trabalho, que se declararam não brancas e moradoras das regiões Nordeste e Norte do país. A tipologia de classe social utilizada neste estudo foi válida para capturar desigualdades na autopercepção da saúde bucal e da saúde geral de adultos, à semelhança da renda domiciliar per capita e da escolaridade, com diferenciais apenas na força de associação, a depender do desfecho e do sexo. A compreensão da relação dos marcadores de desigualdade da autoavaliação da saúde bucal e da saúde geral pode levar ao melhor direcionamento de políticas públicas para grupos sociais mais vulneráveis, contribuindo para a redução das iniquidades em saúde que persistem no Brasil. / The objective of the study was to analyze the relationship between health inequality markers, with emphasis on the socioeconomic position, with the self-assessment of oral health and general health of the Brazilian adult population in 2013. A total of 59,758 individuals aged 18 years and older participated in the National Health Survey 2013, a population-based household survey. The dependent variables on the study were selfassessment of oral health (teeth and gums) and self-assessment of general health, both of which were analyzed as positive, regular and negative. The independent variables were the markers of health inequality (color or race, residence area, education, per capita household income and social class). Crude and adjusted odds ratios (OR) and 95% confidence intervals (95% CI) were computed using multinomial logistic regression models. Results regarding general self-rated health were stratified by gender. The prevalence of self-assessment of positive oral health was 67.4%, 26.7% for regular and 5.9% for negative, while for general health were 66.2%, 28.0% and 5.8%, respectively. Women evaluate their overall health worse than men. After adjustment, the probability of rating their oral health as negative was significantly higher among individuals with a per capita household income up to a minimum wage (OR=4.71, 95%CI: 2.84-7.83), no schooling (OR=3.28, 95%CI: 2.34-4.61), of the social class devoid of assets (OR=3.03, 95%CI: 2.12-4.32) and living in the northeast region (OR=1.50, 95%CI: 1.19-1.89). Regarding the self-assessment of general health in men, the odds of evaluating worse were significantly higher among individuals with lower per capita household income, with lower educational level, people outside the work force, residents of the Northeast and North regions, and declared themselves brown and black. While in women, the chances of a worse evaluation of their general health status were higher among those with the lowest level of schooling, lower per capita household income, who were outside the work force, who declared themselves as nonwhites and residents of the Northeast and North regions of the country. The social class typology used in this study was valid to capture inequalities in self-perception of oral health and general health of adults, similar to per capita household income and education, with differentials only in strength of association, depending on the outcome and gender. Understanding the relationship between the inequality markers of oral health selfassessment and general health can lead to improvement of public policies to vulnerable social groups, contributing to the reduction of health inequities that persist in Brazil.

Mit der vorliegenden Arbeit werden aktuelle Anwendungsbereiche der Lebensqualitätsforschung innerhalb der klinischen Medizin dargestellt. Besonderes Gewicht wurde dabei auf die Erläuterung der Grundlagen der Lebensqualitätsforschung und der derzeit verbreiteten Konzepte, die Diskussion aktueller und zukünftiger Messmethoden sowie die Darstellung einiger typischer Anwendungen gelegt. Der letzte Teil der Arbeit weist auf die bereits erkennbaren Grenzen und ethischen Konsequenzen dieser Forschungsrichtung hin. In der Habilitationsschrift werden verschiedene Originalarbeiten zusammengefasst, denen jeweils eine allgemeine Einführung zur leichteren thematische Einordnung vorangestellt ist. / This volume demonstrates the present scope of 'Quality of Life' research within a clinical context. Different chapters describe the foundations and the development of 'Quality of Life' research, presently used concepts, discussions about appropriate measurement models and some perspectives for an improvement of psychometric methods. Further, different applications and purposes to use 'Quality of Life' instruments in a clinical context are demonstrated. The last part discusses particular ethical consequences and other limitations of 'Quality of Life' research. All chapters combine introductory sections with published original works.

Introdução: Conhecida desde os tempos de Hipócrates, a varicela é autolimitada e isenta de complicações na maioria dos casos, mas responde por absenteísmo escolar das crianças e laboral dos cuidadores, além de hospitalizações e óbitos em pacientes previamente hígidos. Após a incorporação da vacina varicela no calendário americano em 1995, diversos países têm verificado suas epidemiologias para análise de custo-benefício da vacinação; alguns já vêm publicando resultados do impacto da vacina. O Brasil incluiu a vacina no calendário vacinal para crianças de 15 meses em 2013 e vem avaliando o seu impacto. Objetivos: Aprimorar dados pré-vacinais num hospital universitário de atenção secundária, descrevendo atendimentos de Pronto-Socorro Infantil (PSI), hospitalizações e internações em unidade de terapia intensiva (UTI) por varicela; caracterizar o perfil etário, sazonalidade e diagnósticos das complicações da doença, além de analisar possíveis fatores de risco para internação e evolução grave. Metodologia: Estudo retrospectivo descritivo de crianças e adolescentes menores de 15 anos com varicela, no período entre janeiro de 2003 e dezembro de 2012. Relacionamos os resultados à população local para calcular taxas de incidência, hospitalização, internação em UTI e óbito relacionadas à doença. O registro informatizado do hospital forneceu a lista de pacientes com diagnóstico de varicela no atendimento de PSI ou na internação; prontuários foram consultados para coleta de dados que foram submetidos a análise em programas estatísticos. Resultados: Ocorreram 8520 atendimentos em PSI com varicela, 508 destes (6,0%) sendo hospitalizados, 36 destes últimos (7,1%) necessitando de UTI e 2 óbitos (0,4% dos internados), fornecendo as seguintes taxas médias anuais: 887,5 atendimentos, 52,9 hospitalizações, 3,8 internações em UTI e 0,21 óbitos para 100.000 habitantes até 15 anos. Crianças abaixo de 5 anos representaram 75% dos atendimentos, 92,3% das hospitalizações e 88,9% das internações em UTI. Lactentes entre 12 e 15 meses representaram 4,5% dos atendimentos, 6,5% das hospitalizações e 6,1% das internações em UTI. O segundo semestre do ano representou 89,4% dos atendimentos de PSI. Os menores de 5 anos atendidos no PSI tiveram 4,3 vezes maior chance de internação que os maiores de 5 anos, mas a idade não representou diferença no risco para necessidade de UTI. Infecções de pele e partes moles causaram 72,6% das hospitalizações, enquanto problemas respiratórios e neurológicos responderam por 20,1% e 1%, respectivamente. O motivo principal da indicação de UTI foi instabilidade hemodinâmica; 58,3% necessitaram de drogas vasoativas. Comparando os que necessitaram de UTI e os que não necessitaram, os primeiros apresentavam maior tempo de varicela à admissão, febre mais prolongada após internação, maior quantidade absoluta e relativa de neutrófilos e suas formas jovens, Proteína C reativa mais alta e plaquetas reduzidas nos exames admissionais. Conclusão: As taxas epidemiológicas verificadas neste estudo se mostraram dentro do descrito em literatura; as infecções secundárias de pele e partes moles na varicela, sem CID10 específico, prevalecem sobre complicações como pneumopatia, meningite e encefalite, que possuem descritores específicos, como causas de internação e dados de história e exames admissionais podem ajudar a apontar gravidade / Introduction: Known since Hippocrates times, varicella is self-limited and complication-free in most cases, but it responds to school and labor absenteeism of children and caregivers, as well as previously healthy patients hospitalizations and deaths. After varicella vaccine was recommended for routine use in United States in 1995, several countries reviewed their epidemiology for cost-benefit analysis of vaccination; some of then published vaccine impact results. Brazil included varicella vaccine in immunization routine for 15 months child in 2013 and has been appraising its impact. Objectives: Improve pre-vaccination data from secondary care university hospital describing pediatric urgent care (PUC) assessment, inpatient department and pediatric intensive care unit (PICU) hospitalizations; define age profile, seasonality and varicella complications diagnoses and analyze hospitalization and severe evolution possible risk factors. Methods: This report is aimed to retrospectively discriminate children and adolescents under 15 years with varicella from January 2003 to December 2012. Local population was considered to propose varicella-related PUC visit, hospitalization, PICU stay and death rates. Hospital registration provided computerized varicella-diagnosed PUC assessment, inpatient and PICU patient list; data collected from its charts were submitted to statistical program analysis. Results: 8520 PUC varicella cases were reported, 508 of them (6.0%) were hospitalized, 36 of them (7.1%) required PICU and 2 died (0.4% of hospitalized patients), providing following annual rates: 887.5 assessments, 52.9 hospitalizations, 3.8 PICU admissions and 0.21 deaths per 100,000 inhabitants up to 15 years. Children younger than 5 years accounted for 75% of PUC visits, 92.3% of hospitalizations and 88.9% of PICU admissions. Infants between 12 and 15 months represented 4.5% of PUC visits, 6.5% of hospitalizations and 6.1% of PICU admissions. Second half of the year accounted 89.4% of PUC attendances. Under 5 years PUC child had 4.3 more hospitalization risk than those older than 5 years, but age did not represent difference in PICU risk. Skin and soft tissue infections caused 72.6% of hospitalizations, while respiratory and neurological problems accounted for 20.1% and 1%, respectively. The main reason for PICU indication was hemodynamic instability; 58.3% required vasoactive drugs. Comparing those who needed PICU and those who did not need them, the former had longer time of varicella on admission, longer fever after hospitalization, greater absolute and relative amount of neutrophils and their young forms, higher C-reactive protein levels and reduced platelets in admission exams. Conclusion: epidemiological rates verified in this study were within described in literature; secondary skin infections and soft tissues in varicella, without specific ICD-10, overcome complications as pneumopathy, meningitis, and encephalitis, which have specific descriptors; anamnesis and admission examinations data may help predict severity