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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
261

Effects of land-use intensity in grasslands on diversity, life-history traits and multitrophic interactions / Auswrikungen der Landnutzungsintensität in Grünländern auf Diversität,

Börschig, Carmen 07 March 2012 (has links)
No description available.
262

Étude intracrânienne sur les mécanismes cérébraux permettant la reconnaissance d’objets

Bertrand, Josie-Anne 06 1900 (has links)
La reconnaissance d’objets est une tâche complexe au cours de laquelle le cerveau doit assembler de manière cohérente tous les éléments d’un objet accessible à l’œil afin de le reconnaître. La construction d’une représentation corticale de l’objet se fait selon un processus appelé « bottom-up », impliquant notamment les régions occipitales et temporales. Un mécanisme « top-down » au niveau des régions pariétales et frontales, facilite la reconnaissance en suggérant des identités potentielles de l’objet à reconnaître. Cependant, le mode de fonctionnement de ces mécanismes est peu connu. Plusieurs études ont démontré une activité gamma induite au moment de la perception cohérente de stimuli, lui conférant ainsi un rôle important dans la reconnaissance d’objets. Cependant, ces études ont utilisé des techniques d’enregistrement peu précises ainsi que des stimuli répétitifs. La première étude de cette thèse vise à décrire la dynamique spatio-temporelle de l’activité gamma induite à l’aide de l’électroencéphalographie intracrânienne, une technique qui possède des résolutions spatiales et temporelles des plus précises. Une tâche d’images fragmentées a été conçue dans le but de décrire l’activité gamma induite selon différents niveaux de reconnaissance, tout en évitant la répétition de stimuli déjà reconnus. Afin de mieux circonscrire les mécanismes « top-down », la tâche a été répétée après un délai de 24 heures. Les résultats démontrent une puissante activité gamma induite au moment de la reconnaissance dans les régions « bottom-up ». Quant aux mécanismes « top-down », l’activité était plus importante aux régions occipitopariétales. Après 24 heures, l’activité était davantage puissante aux régions frontales, suggérant une adaptation des procédés « top-down » selon les demandes de la tâche. Très peu d’études se sont intéressées au rythme alpha dans la reconnaissance d’objets, malgré qu’il soit bien reconnu pour son rôle dans l’attention, la mémoire et la communication des régions neuronales distantes. La seconde étude de cette thèse vise donc à décrire plus précisément l’implication du rythme alpha dans la reconnaissance d’objets en utilisant les techniques et tâches identiques à la première étude. Les analyses révèlent une puissante activité alpha se propageant des régions postérieures aux régions antérieures, non spécifique à la reconnaissance. Une synchronisation de la phase de l’alpha était, quant à elle, observable qu’au moment de la reconnaissance. Après 24 heures, un patron similaire était observable, mais l’amplitude de l’activité augmentait au niveau frontal et les synchronies de la phase étaient davantage distribuées. Le rythme alpha semble donc refléter des processus attentionnels et communicationnels dans la reconnaissance d’objets. En conclusion, cette thèse a permis de décrire avec précision la dynamique spatio-temporelle de l’activité gamma induite et du rythme alpha ainsi que d’en apprendre davantage sur les rôles potentiels que ces deux rythmes occupent dans la reconnaissance d’objets. / Recognizing objects is a complex task requiring the brain to assemble visual information in such a way that coherent perception can happen. Building a visual cerebral representation is done through a bottom-up process, involving mainly occipital and temporal areas. A top-down mechanism from parietal and frontal areas, is thought to facilitate recognition by taking into account expectations and generating possible candidates. However, the precise mechanisms by which all these processes are done are still unclear. Studies investigating induced gamma response were able to link this activity to coherent perception of objects, suggesting a significant role of this activity in object recognition. However, these studies used imprecise recording techniques and stimuli repetition. The first study of this thesis aimed at describing with more precision the induced gamma activity using intracranial encephalography and a fragmented images paradigm in which only new stimuli are presented. Moreover, the task was presented again 24 hours later to circumscribe top-down mechanisms. Results show that the induced gamma activity is highest at recognition in regions involved in bottom-up processes. Top-down mechanism involved occipito-parietal areas when images were presented for the first time. When images were presented again 24 hours later, frontal areas mediated top-down facilitation, suggesting that top-down mechanisms vary according to task demand. Alpha rhythm has been less clearly related to visual perception, but is nevertheless well known to be involved in attention, memory and long-distance brain communication. The second study of this thesis investigated the role of alpha rhythm in object recognition, using the same technique and task as in the first study. Time-frequency analysis revealed a strong alpha activity unspecific to recognition, which was propagating from posterior to anterior regions. Phase coherence analysis, however, showed significant phase synchronisation specific to recognition. A similar pattern of alpha activity was found 24 hours later. However, the activity was stronger in frontal regions and the phase synchronisation was more distributed. Alpha rhythm is thus thought to be involved in attentional and communicational mechanisms of object recognition. In conclusion, this thesis was able to describe the precise spatio-temporal dynamics of induced gamma and alpha activity and suggest potential roles of these rhythms in response to object recognition.
263

[en] BAYESIAN STOCHASTIC EXTENSION OF DETERMINISTIC BOTTOM-UP APPROACH FOR THE LONG TERM FORECASTING OF ENERGY CONSUMPTION / [pt] EXTENSÃO ESTOCÁSTICA BAYESIANA DA ABORDAGEM BOTTOM-UP DETERMINÍSTICA PARA A PREVISÃO DE LONGO PRAZO DO CONSUMO DE ENERGIA

FELIPE LEITE COELHO DA SILVA 16 February 2018 (has links)
[pt] O comportamento do consumo de energia elétrica do setor industrial tem sido amplamente investigado ao longo dos últimos anos, devido a sua importância econômica, social e ambiental. Mais especificamente, o consumo de eletricidade dos subsetores da indústria brasileira exerce grande importância para o sistema energético brasileiro. Neste contexto, as projeções de longo prazo do seu consumo de energia elétrica para um país ou uma região são informações de grande relevância na tomada de decisão de órgãos e entidades que atuam no setor energético. A abordagem bottom-up determinística tem sido utilizada para obter a previsão de longo prazo em diversas áreas de pesquisa. Neste trabalho, propõe-se uma metodologia que combina a abordagem bottom-up com os modelos lineares hierárquicos para a previsão de longo prazo considerando os cenários de eficiência energética. Além disso, foi utilizada a inferência bayesiana para a estimação dos parâmetros do modelo, permitindo a incorporação de incerteza nessas previsões. Os resultados utilizando os dados de consumo de eletricidade de subsetores da indústria brasileira mostraram que a metodologia proposta consegue capturar a tajetória do consumo de eletricidade, em particular, dos subsetores de papel e celulose, e de metais não-ferrosos e outros de metalurgia. Por exemplo, os intervalos de credibilidade de 95 por cento construídos a partir do modelo estocástico contemplam os valores reais observados nos anos de 2015 e 2016. / [en] The electricity consumption behaviour in the Brazilian industry has been extensively investigated over the past years due to its economic, social and environmental importance. Specifically, the electricity consumption of the subsectors of Brazilian industry have great importance for the Brazilian energy system. In this context, the long-term projections of energy consumption of a country or region are highly relevant information to decision-making of organs and entities operating in the energy sector. The deterministic bottom-up approach has been used for the long-term forecast in several areas of research. In this paper, we propose a methodology that combines the bottom-up approach with hierarchical linear models for long-term forecasting considering energy efficiency scenarios. In addition, Bayesian inference was used to estimate the parameters of the model, allowing the uncertainty incorporation in these forecasts. The results using the electricity consumption data from subsectors of the Brazilian industry showed that the proposed methodology is able to capture the trajectory of their electricity consumption, in particular of the pulp and paper, and of non-ferrous metals and other metallurgical subsectors. For example, the 95 percent credibility intervals constructed from the stochastic model contemplate the actual values observed in the years 2015 and 2016.
264

L’énergie solaire pour la production d’électricité au Maghreb : transition énergétique et jeux d’échelles / Using solar energy for power generation in the Maghreb : energy transition and scales

Benalouache, Nadia 30 June 2017 (has links)
La transition énergétique « bas carbone » au Maghreb, analysée sous l’angle du déploiement de l’énergie solaire pour la production d’électricité, est appréhendée dans un double contexte euro-méditerranéen et national. Elle est notamment le fruit de projets imaginés par des structures supranationales et décidés au plus haut niveau des États. À l’échelle euro-méditerranéenne, des initiatives ont été mises en place pour appuyer le développement à grande échelle de l’énergie solaire, qu’elles émanent de dispositifs intergouvernementaux (Plan Solaire Méditerranéen en 2008) et de consortia industriels privés (Desertec Industrial Initiative, Medgrid en 2009). À l’échelle nationale, les trois pays du Maghreb (Algérie, Maroc, Tunisie) ont formulé, surtout depuis 2009, des politiques de développement des énergies renouvelables, et élaboré, pour leur mise en œuvre, des plans et programmes nationaux. L’objet de cette thèse est d’analyser la mise en œuvre de la transition énergétique « bas carbone » au Maghreb et d’en montrer les implications spatiales et relationnelles aux échelles euro-méditerranéenne et nationale. Ainsi, nous montrons en quoi l’électricité contribue à redéfinir la mise en réseau des espaces régionaux et dans quelles mesures la diffusion des technologies solaires participe à redessiner la géographie de l’électricité au Maghreb. L’objet technique (infrastructure de réseau et unité de production d’électricité à partir de l’énergie solaire) est appréhendé à partir d’une approche systémique, à l’interface des sphères spatiale, politique et économique et sociale. / The « low carbon » transition in the Maghreb, analyzed with a focus on the deployment of solar energy for electricity generation, is considered in both a Euro-Mediterranean and national context. This transition is the result of projects that were designed by supranational organizations and agreed on at the highest level. On a Euro-Mediterranean level, initiatives were implemented to support a large scale development of solar energy, whether it be at an intergovernmental level (Mediterranean Solar Plan, 2008), by private industrial consortia (Desertec Industrial Initiative, Medgrid 2009). At national level, the three Maghreb countries (Algeria, Morocco, Tunisia), have formulated explicit renewables development policies, (especially since 2009), and established national plans and programs (Moroccan Solar Plan, Tunisian Solar Plan, National Renewable and Efficiency Energy Program in Algeria). The purpose of this thesis is to explore the implementation of the « low carbon » transition in the Maghreb and show what spatial and relational implications it had both at European and national level. Thus, we explain how electrical energy contributes to redefine how regional areas connect and to what extent the implementation of solar technologies helps reshape the geography of electrical energy in the Maghreb. The technical aspect (network infrastructure and electricity production unit by solar energy) will be studied following a systemic approach, at the crossroads of spatial, social, political and economical spheres. / الملخص تسعى الأطروحة إ لى تحليل الانتقال نحو الطاقات الىتجددة وخاصة الشمسية بأقطار الىغرب العربي من خلالإطارين : إطارأورو - متوسطي و إطار قطري مح . يبدو الانتقال الطاقي وكأنه نتاج لىشاريع أعدتها هياكل فوق قطرية .ك ما أن إقرارها تم لى تموضع مبادرات تهدف إ لى ، أ ع ا لى ستويات السياسية . فع الىستوى ا لا ورو - متوسطي استعمال الطاقة الشمسية ع نطاق واسع وهذه الىبادرات ناشئةعن ترتيبات ب ين .(2008 - خطة الطاقة الشمسية الىتوسطية 2009 الحكومات ) مبادرة ديزرتاك اهتمت الأطروحة بأقطار الىغرب العربي الثلاثة )تونس - الجزائر - الىغرب ( مجسدة لى ثلاثة برامج كلى ى : خطة الطاقة الشمسية الىغربية، الىخطط الشم التون ، ا ل لىنامج الوطني للطاقة الىتجددة وكفاءة الطاقة لى الجزائر . إن الغرض من الأطروحة هو كذلك تحليل الانتقال الطاقي بشمال إفريقيا وإبراز أثارها الىجالية والعلائقية ع الىستوىا لا ورو - متوسطي و ع الىستويات الوطنية، ك ما نسعى إ لى إبراز كيفة مساعدة الطاقة الشمسية ع إعادة تعريف الشبكات غ الىستوى الإقليمي وكيف أن إعادة توزيع تكنولوجيا الطاقة الشمسية تشارك لى إعادة رسم جغرافية الكهرباء بشمال إفريقيا .
265

Estratégia atencional para busca visual e reconhecimento invariante de objetos baseada na integração de características bottom-up e top-down / Attentional strategy for visual search and invariant object recognition based on bottom-up and top-down feature integration

Evelina Maria de Almeida Neves 30 June 2000 (has links)
Uma das tarefas básicas dos mecanismos atencionais é decidir qual a localização dentro do campo visual, em que devemos prestar atenção primeiro. Um objeto que contenha características distintas, tais como orientação, forma, cor, tamanho, brilho, textura, etc. diferentes, pode atrair a atenção de uma maneira \"bottom-up\". A informação \"top-down\" baseia-se no conhecimento prévio e tem uma grande influência nas localizações atendidas. Inspirado nos mecanismos da Atenção Visual Humana, embora sem a pretensão de simulá-la, este trabalho prevê o desenvolvimento de uma nova metodologia que integra os dois tipos de informações: \"bottom-up\" e \"top-down\". Características \"bottom-up\" são geradas a partir de Momentos e essas informações são utilizadas em mapas de saliência, enquanto que um conhecimento prévio é utilizado para gerar pistas \"top-down\". Neste trabalho, desenvolveu-se uma metodologia específica para a busca e o reconhecimento visual em cenas com múltiplos objetos, utilizando para isso uma rede \"fuzzy\" contendo três subsistemas \"fuzzy\". Dada uma imagem de entrada, o objetivo consiste em se detectar regiões que possam conter informações mais significativas, a fim de que se possa guiar e restringir processamentos mais complexos. A inclusão de mecanismos de atenção (seleção de uma região de interesse dentro da imagem) é de fundamental importância pois os resultados obtidos pelo método podem ser usados para controlar a aquisição da imagem de uma maneira dinâmica. O modelo proposto está estruturado em três estágios principais: O primeiro estágio consiste em se segmentar os objetos e extrair características globais dos mesmos baseadas principalmente na teoria dos momentos, tais como tamanho, orientação, formato e distância e também média de nível de cinza. Por intermédio da comparação de um objeto com os outros presentes na cena, características \"bottom-up\" de conspicuidade são usadas para guiar a atenção ao objeto mais diferente. Por intermédio do uso da lógica \"fuzzy\" é possível inferir com grande flexibilidade algumas regras de decisão baseadas nos princípios de percepção visual tais como as leis Gestalt. O segundo estágio consiste de um subsistema \"fuzzy top-down\" que combina diferentes características de acordo com a relevância das mesmas em diferentes tarefas. Finalmente, o terceiro estágio consiste de um subsistema \"fuzzy\" que integra as informações obtidas dos subsistemas anteriores e fornece um índice geral de saliência, e indica a provável localização do objeto a ser reconhecido. A nova abordagem foi testada com objetos geométricos levando-se em consideração as características que atraem a atenção dos serem humanos / One of the basic tasks assigned to the human attentional mechanisms is to decide which location in the visual field we must pay attention first. An object containing distinctive features (such as different orientation, shape, color, size, shine, texture, etc.) can attract attention in a bottom-up way. Top-down information is based on the previous knowledge and has a large influence on the attended locations. Inspired on human visual attention mechanisms, although it doesn\'t want simulate it, this work presents a new methodology to integrate two different kind of information: bottom-up and top-down. Bottom-up features are obtained from Moment Theory and this information is used in salience maps, while a previous knowledge is used to create top-down hints. In this work, an specific methodology to visual search and recognition was developed to be applied to scenes containing multiple objects by a fuzzy net with three fuzzy subsystems. The aim of this methodology is to detect regions that may contain the most significant information, in order to guide and to restrict most complex processing. The inclusion of attentional mechanisms (the selection of a region of interest in the image) is fundamental and can be used to control the image acquisition in a dynamic way. The proposed model is structured in three main stages. The first stage segments the objects and extracts global features of them, based on the Moment Theory such as size, orientation, shape and distance and gray level average. By comparing one object with the other ones present in the scene, bottom-up features of conspicuity are used to guide the attention to the most different object. The Fuzzy Logic allows us to infer with great flexibility some of decision rules based on the visual perception principles such as the Gestalt Laws. The second stage is a top-down fuzzy subsystem that combines different features according to the relevance of them in different tasks. Finally, the third stage is a fuzzy subsystem that integrates the information obtained from the previous sub-systems and gives us a general salience index. The new methodology was tested in geometrical objects considering the feature that attracts attention to human beings
266

"Det är inte bara folkvalda politiker som utövar offentlig makt" : En jämförande studie gällande främjande av integration i fem kommuner i Stockholms län / "It is not just elected representatives that exercise public power" : A comparative study of integration in five municipalities in Stockholm County

Degard, Emelie, Abdulla, Maya January 2009 (has links)
Based on different integration policies, we aim to examine how five municipalities in Stockholm County are working to promote integration at a local level with focus on voter participation and to some extent, representativeness among foreign-born. Statistics provided by SCB shows that foreign-born tends to vote to a lesser extent than those born in Sweden. Further, we aim to examine the implementation of two policy documents established at a national level concerning integration in contrast to policy documents established at a local level in each different municipality. Further, we aim to examine summaries of actions taken in response to the local integration programs, as well as personal interviews. Each municipality will be considered separately, but we thus seek to make a comparative study. The study will be based on a qualitative approach. The implementation process of both central and local policy decisions concerning the promotion of integration will also be discussed in terms of two existing theories of implementation, based on two different perspectives. The result shows that interaction between different participants, such as local officials and politicians, is of importance for the implementation process. All of the studied municipalities have taken some actions in order to implement their goals concerning integration.
267

Renaissance de l'habitat participatif en France : vers de nouvelles formes négociées de fabrication de la ville ? Deux études de cas dans l'agglomération bordelaise : le projet HNord (Bordeaux) et La Ruche (Bègles) / Revival of participative housing in france : towards new negotiated forms of urban production. Two case studies in the Bordeaux area : HNord (Bordeaux) and La Ruche (Begles)

Darroman, Mélanie 11 December 2014 (has links)
Cette thèse interroge les effets combinés des enjeux d’un urbanisme durable et d’un impératif participatif grandissant des habitants – usagers – citoyens, dans le cadre de la fabrication métropolitaine contemporaine. Depuis le début des années 2000, des expériences alternatives d’habitat émergent en France sous l’impulsion de revendications sociales portées par la société civile. Le terme générique d’« habitat participatif », définit récemment par la loi pour l’Accès au Logement et à un Urbanisme Négocié (ALUR), publiée au Journal Officiel le 26 mars 2014, rassemble ainsi d’une même voix la variété de ces initiatives à l’œuvre, contribuant à pérenniser les dynamiques de structuration et de diffusion d’un mouvement de l’habitat participatif. Faisant référence aux expressions citoyennes contestataires des années 1970-1980, avec la critique d’un urbanisme moderne et des politiques publiques, les projets actuels marquent la renaissance des questionnements autour de la place de la maîtrise d’usage – incarnée par les habitants-usagers – dans la chaîne de production des logements et, plus largement, dans les processus décisionnels d’aménagement des territoires. Porteuse de pratiques participatives innovantes, la résurgence de l’habitat participatif révèle des logiques diverses d’engagements citoyens, militants ou professionnels, et des formes négociées de fabrication de l’habitat. Dès lors, s’opposent des dynamiques « bottom-up » – illustrées par des demandes et des initiatives habitantes, et des dynamiques « top-down » – portées par des instances politico-institutionnelles en plein renouvellement de leurs modes d’action et savoir-faire. Supportée par une trame multidimensionnelle de négociations, la thèse propose alors une analyse des interactions et des formes d’hybridation de cette production collective en cours à travers trois dimensions : la dimension valorielle, pour fixer le socle des transactions sociales ; la dimension organisationnelle et relationnelle, pour observer la micropolitique des groupes-projets ; la dimension processuelle, pour saisir les temporalités du projet et les moments clés de la négociation sur l’ensemble du processus. Pour cela, nous nous appuyons sur deux cas d’étude dans l’agglomération bordelaise, en pleine métropolisation : le cas de la coopérative d’habitants HNord, sur l’îlot Dupaty à Bordeaux ; et celui d’un projet d’habitat participatif multi-partenarial, La Ruche, sur la commune de Bègles au sein de l’Opération d’Intérêt National (OIN) Bordeaux-Euratlantique. Encadrée par un dispositif CIFRE avec l’Etablissement Public d’Aménagement Bordeaux-Euratlantique (EPA), la recherche repose sur une approche ethnographique, basée sur de nombreuses situations d’observation participante, des entretiens d’acteurs cibles et une analyse documentaire. Les enquêtes menées à différentes échelles offrent une vision macro, méso et microsociale des processus de production et de diffusion de l’habitat participatif. Les résultats de la thèse mettent alors en évidence les modalités de partenariats entre différentes sphères d’acteurs – les habitants, les institutions et les experts – dans la production de l’habitat participatif conduisant à un changement de paradigme sociétal et professionnel à travers le renouvellement des modes d’habiter, des savoirs et savoir-faire. Ainsi, nous proposons une réflexion sur les moyens et possibilités d’intégration de cette dynamique collective et citoyenne au sein des processus décisionnels d’aménagement urbain pour la fabrication métropolitaine et, de voir en quoi ce phénomène participatif et collaboratif peut-il constituer un outil de management territorial novateur préfigurant le futur de nos cités. / This PhD thesis questions the combined effects of the challenges of sustainable urban development and a growing priority for inhabitants – users – citizens, to participate in contemporary metropolitan production. Since the early 2000s, there is in France an emergence of alternative housing experiences as a result of social demands. The generic term of « participative housing », recently defined by the bill for access to housing and urban renovation (ALUR), published in the Official Journal on March 26, 2014, gathers with one voice, the variety of these initiatives at work, contributing to ensure the dynamic structuring and dissemination of the participative housing movement. Referring to the civil protests of 1970-1980, criticizing modern urban planning and public policy, the current projects tackle once again of how to combine the inhabitants expertise with professional expertise in the production of housing, and more broadly in the decision-making processes of regional planning. Producing innovative participatory practices, the resurgence of participative housing reveals different logics of social commitments on the part of citizens, activists and professionals, and negotiated forms of housing production. As a consequence, the « bottom-up » dynamic, based on the demands and initiatives of the inhabitants, opposes the « top-down » dynamic, based on the initiative of politico-institutional bodies in full renewal of their modes of action and know-how. Supported by a multi-dimensional framework of negotiations, the thesis analyzes the interactions and forms of hybridization of this ongoing collective production through a three dimensional approach : the value related dimension, to set the base of social transactions ; the organizational and relational dimension to observe the micro-political groups-projects ; the procedural dimension to grasp the temporality of the project and the key moments of negotiation of the whole process. For this, we build on two case studies in the Bordeaux area, being subject to processes of metropolization : the case of the residents cooperative HNord in the Dupaty housing block in Bordeaux ; and the multi-partnered participative housing project, La Ruche, in the town of Bègles within the framework of the « Operation of National Interest » (OIN) Bordeaux-Euratlantique. Governed by a CIFRE program with the « Local Planning and Development authority » (EPA) Bordeaux-Euratlantique, the research is based on an ethnographic approach : participant observation, interviews with target stakeholders and a literature review. The investigations conducted at different scales offer a macro, meso and micro-social understanding of the process of participative housing production and dissemination. The results of the thesis highlight the partnership conditions between different groups of stakeholders – inhabitants, institutions and expertsn – in the production of participative housing leading to a societal and professional paradigm shift through a renewal of ways of living, knowledge and expertise. Thus, we propose a reflection on ways and possibilities how to integrate this collective and civic dynamics in the decision-making processes of urban planning for metropolitan production and to see how this participatory and collaborative phenomenon can serve as an innovative tool in territorial management for our future cities.
268

Využití radikálového značení bílkovin pro strukturní biologii / Utilization of protein radical foootprinting for stuctural biology

Polák, Marek January 2020 (has links)
(In English) The reaction of highly reactive oxygen radicals with protein solvent-accessible residues can be utilized to map protein landscape. Fast photochemical oxidation of proteins (FPOP) is an MS- based technique, which utilizes highly reactive radical species to oxidize proteins and map protein surface or its interactions with their interaction partners. In this work, FPOP was employed to study protein-DNA interactions. First, a full-length of FOXO4-DBD was successfully expressed and purified. The ability of the protein to bind its DNA-response element was verified by electrophoretic and MS-based techniques, respectively. Optimal experimental conditions were achieved to oxidize the protein itself and in the presence of DNA, respectively. Oxidized samples were analyzed by bottom-up and top-down approach. In the bottom-up experiment, modification of individual residues was precisely located and quantified. Different extend of modification was observed for protein alone and in complex with DNA. To avoid experimental artifacts analyzing multiply oxidized protein, standard bottom up approach was replaced by a progressive top-down technology. Only a singly oxidized protein ion was isolated, and further fragmented by collision-induced dissociation (CID) and electron-capture dissociation (ECD),...
269

Temporär urbanism : Hur konceptet kan tillämpas i svensk kontext för att kurera urbana rum / Temporary urbanism : How the concept can be utilized in Swedish context to curate urban spaces

Tellstig, Sara, Elocin, Nicole January 2024 (has links)
“Temporary urbanism” is a concept that can go by a number of different names and can take different forms. This means that the concept has a dynamic and experimental character, it can represent different types of uses and needs of different target groups and users. The concept originates from New York, during the 20th-century, and usually involves an urban planning strategy that promotes social sustainability by reducing the car use in cities and instead shift the focus to the citizens. Temporary urbanism can therefore act as a catalyst to change the norm and meaning of urban spaces, and who they are for. In the Swedish context, information about the concept is not available to everyone, as it is limited to existing within urban planning and is therefore primarily aimed at top-down initiated projects. If temporary urbanism is to be represented in the right way, as a flexible and versatile tool, more target groups need to be able to use the concept, in order to create their own initiatives in urban spaces. If the public space, evaluated as a resource, is not used all year round in different ways and by a variation of target groups, it would become what we call wasted space. Hence, citizens must be given access to proper tools in order to influence the development of the urban spaces and what they contain. Throughout the bachelor's thesis, desk studies have been used, supplemented with interviews and an example of the trendy concept of “summer streets”. All this to understand how temporary urbanism commonly is expressed in Sweden and what potential development the concept has in the utilization in Swedish context. This thesis has resulted in a design proposal for a handbook. The handbook summarizes and analyzes the concept of temporary urbanism and its use in the Swedish context. It also showcases international examples of how the concept could be expressed broadly and diversified to inspire. The handbook results in an understanding of how awareness can increase, create an understanding of the concept, and promote citizen participation in the design of public spaces. It clarifies the concept of temporary urbanism and makes it accessible for all, so that more people can use the strategies it includes to curate urban spaces. / “Temporär urbanism” är ett begrepp som kan gå under en rad olika benämningar och kan ta olika skepnader. Det innebär att konceptet har en dynamisk och experimentell karaktär, det kan representera olika typer av användningar samt olika målgruppers och användares behov. Konceptet har sitt ursprung i New York, under 1900-talet, och innebär oftast en stadsplaneringsstrategi som främjar social hållbarhet genom att minska bilismens starka fäste i staden för att istället skifta fokuset till medborgarna. Temporär urbanism kan därför fungera som katalysator för att förändra normen för vad urbana rum innebär och vilka de är till för. I svensk kontext är informationen om detta koncept inte tillgängligt för alla, då den begränsas till att vara ett begrepp inom stadsplaneringen och riktar sig därför främst till top-down initierade projekt. Om temporär urbanism ska representeras på rätt sätt, som ett flexibelt och mångsidigt verktyg, behöver fler målgrupper kunna använda sig av konceptet för att ta egna initiativ i urbana rum. Om stadsrummet, sedd som resurs, inte utnyttjas året om på olika sätt och av varierande målgrupper, skulle det bli vad vi kallar ett outnyttjat utrymme. Därav måste medborgare ges tillgång till goda verktyg för att få påverka utvecklingen av stadsrummen och vad de innehåller. Genom uppsatsen har skrivbordsstudier använts, kompletterat med intervjuer och ett typexempel av det trendiga konceptet “sommargator”, även kallat “sommargågator”. Detta för att förstå hur temporär urbanism oftast uttrycker sig i Sverige och därmed vad konceptet har för utvecklingspotential i tillämpningen i den svenska kontexten.  Denna uppsats har mynnat ut i ett designförslag av en handbok. Handboken sammanfattar och analyserar konceptet temporär urbanism och dess användning i svensk kontext. Den tar även upp internationella exempel på hur konceptet skulle kunna uttryckas för att inspirera och visa på bredd och mångfald. Handboken resulterar i att förstå hur medvetenheten kan öka, skapa förståelse för konceptet, främja medborgarnas deltagande i utformningen av stadens offentliga rum. Den tillgängliggör och tydliggör konceptet för temporär urbanism för att fler ska kunna använda sig av strategierna som det innefattar, för att kurera urbana rum.
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Policy development and implementation in the post-liberalization era in Zambia (1990s and beyond): towards a participatory planning and economic management model

Mulungushi, James Shamilimo 03 1900 (has links)
This thesis investigates policy formulation and implementation processes in Zambia. A number of issues emerge with respect to the weaknesses of the system and how policy decisions worsened Zambia's economic performance instead of improving it. The Kaunda era policies of nationalization had an adverse impact on productivity of industries as well as affecting the resource flow from donors and business houses. On the other hand President Chiluba's reforms in the 1990s have had both positive and negative impacts on the people of Zambia. The rapid privatization and liberalization affected employment levels thereby worsening the poverty levels. Further, the liberalization brought in stiff competition from other countries forcing most manufacturing companies to close down. The policy environment based on the Bretton Woods Institutions seems not to be working as result of not taking into account the local Zambian situation. On the other hand, there were positive macroeconomic developments such as growth in GDP, lowering of inflation and stabilizing of exchange rates as from 1996. This has however not improved the living standards of the people. In Zambia, the shifts back and forth between strong and weak planning institutions have negatively affected policy development and implementation. There has been uncoordinated policy development; as a result, some policies in the major sectors are contradictory while in other cases policies are not linked to the resource envelope, making them un-implementable. Secondly, the institutional framework for policy development is not effective. There is generally lack of coordination among ministries, provinces and other stakeholders in planning, implementation and monitoring and evaluation of development programmes. This thesis urges that the improving planning capacities at the national, provincial and district levels should improve the processes of policy development and implementation in Zambia, which will in turn help to reduce poverty. Further, the districts should be the centre for the bottom-up process. In order to carryout this responsibility, efforts should be made to improve their capacities. As for the top-down process, the Sector Advisory Groups should continue to participate in the planning, monitoring and evaluation so as to contribute to policy formulation and implementation. These should be coordinated by the National Development Coordinating Committee (NDCC) through a Planning Bureau. / Development Studies / D. Litt. et Phil. (Development Studies)

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