- About
-
The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 31 to 37 of 37 (0.017 seconds)Spelling suggestions: "subject:"gillis"" "subject:"hillis""
| 31 |
APPLICATION OF MULTISCALE HEMODYNAMIC MODELS TO EXPLORE THE ACTION OF NITRITE AS A VASODILATOR DURING ACUTE CARDIOVASCULAR STRESSJoseph C Muskat (14226884), Elsje Pienaar (658131), Craig Goergen (9040283), Vitaliy L. Rayz (8825411), Charles F. Babbs (430220) 08 December 2022 (has links)
<p>The fluid dynamics of blood in the systemic circulation modulates production of nitric oxide (NO), a potent vasodilator. Non-invasive techniques such as the flow-mediated dilation (FMD) test and physiologic phenomena associated with autonomic stress induce hyperemia and subsequently higher levels of wall shear stress (WSS), stimulating endothelial nitric oxide synthase (eNOS) expression. In the current clinical practice, WSS–a key regulator of endothelial function–is commonly estimated assuming a parabolic velocity distribution, despite the evidence that the temporal changes of pulsatile blood flow over the cardiac cycle modulate vasodilation in mammals. This work investigates the effect of cardiovascular stress on local WSS distributions and the potential for near-wall accumulation of nitrite, the vasoactive storage form of NO in the bloodstream. The specific aims of the project are therefore as follows: 1) develop a reduced-order model of the major systemic vasculature at rest, during a flight-or-flight response, and under moderate levels of aerobic exercise; 2) derive a velocity-driven Womersley solution for pulsatile flow to support accurate estimation of pulsatile WSS in the clinical setting; and 3) quantify cumulative transport of nitrite in a multiscale model of bifurcating vasculature utilizing computational fluid dynamics (CFD). Development of these open-source, translatable methods enable accurate quantification of hemodynamics and species transport during cardiovascular stress. Results detailed herein extend our knowledge about regulation of regional blood flow during autonomic stress, suggest a convergent evolutionary theory for having a complete circle of Willis, and potentially clarify reproducibility concerns associated with the FMD test. </p>
|
| 32 |
Geometric modeling and characterization of the circle of willisBogunovic, Hrvoje 28 September 2012 (has links)
Los derrames cerebrales son una de las causas principales de morbilidad y mortalidad en los países desarrollados. Esto ha motivado una búsqueda de configuraciones del sistema vascular que se cree que están asociadas con el desarrollo de enfermedades vasculares. En la primera contribución se ha mejorado un método de segmentación vascular para lograr robustez en la segmentación de imágenes procedentes de diferentes modalidades y centros clínicos, con una validación exhaustiva. Una vez que el sistema vascular está correctamente segmentado, en la segunda contribución se ha propuesto una metodología para caracterizar ampliamente la geometría de la arteria carótida interna (ACI). Esto ha incluido el desarrollo de un método para identificar automáticamente la ACI a partir del árbol vascular segmentado. Finalmente, en la tercera contribución, esta identificación automática se ha generalizado a una colección de arterias incluyendo su conectividad y sus relaciones topológicas. Finalmente, la identificación de las arterias en un conjunto de individuos puede permitir la comparación geométrica de sus árboles arteriales utilizando la metodología introducida para la caracterización de la ACI. / Stroke is among the leading causes of morbidity and mortality in the developed countries. This motivated a search for the configurations of vasculature that is assumed to be associated with the development of vascular diseases. In the first contribution we improve a vascular segmentation method to achieve robustness in segmenting images coming from different imaging modalities and clinical centers and we provide exhaustive segmentation validation. Once the vasculature is successfully segmented, in the second contribution we propose a methodology to extensively characterize the geometry of the internal carotid artery (ICA). This includes the development of a method to automatically identify the ICA from the segmented vascular tree. Finally in the third contribution, this automatic identification is generalized to a collection of vessels including their connectivity and topological relationships. Identifying the corresponding vessels in a population enables comparison of their geometry using the methodology introduced for the characterization of the ICA.
|
| 33 |
Dimensões dos princípios jurídicos na teoria do direito segundo Willis Santiago Guerra Filho: aspectos de uma contribuição brasileira à filosofia do direito contemporâneaBarros, Donata Aparecida Campos de 12 November 2007 (has links)
Made available in DSpace on 2016-04-26T20:26:10Z (GMT). No. of bitstreams: 1
Donata Aparecida Campos de Barros.pdf: 376264 bytes, checksum: f7dc15c8672941cfef1cbc26283fbf7e (MD5)
Previous issue date: 2007-11-12 / The context in which the current discussion is situated about juridical principles and basic
rights, central in contemporary theory of the right, is what we intend to show with the
Brazilian contribution given by Willis Santiago Gerra Filho, according which, the
fenomenology would offer the best preparation for the necessary overcoming of the
formalistic positivism, without relapsing into some form equally already surpassed of
jusnaturalism.
Like scholar of the Right in our country, Willis Santiago Guerra Filho faces like a challenge
the imperative of renewal of the legal national order, because is totally new the base on
which it links.
The pledge of the Author is to re-interpret the Native Right as a whole, according the
Constitution of the Federative Republic of Brazil , which presupposes an interpretative
activity of the Basic Law itself, but without the rancidness of the legal operators who do
not realize in the objective way as they conceive the Right, such as it was a machine with
which it takes place, when if it was like that, they would be the pieces of this producing
gear of a pseudo knowledge, of disciplinary character. Admirer of Husserl, who preaches
that nothing exists of cognitive content in this production of knowledge, because
knowledge, for him, is an evidence and truth, created from the intuition, whole and
completely understood, what is lost to the being broken the link with the domain of the
objects about which we should be informed, our Author goes decidedly for the good field
of the pre-scientific verification, in order to value the original right of these evidences,
before rejected and, from there, the essential connection to be able to search between the
sciences / O contexto em que se situa o debate actual sobre princípios jurídicos e direitos
fundamentais, central em teoria do direito contemporânea, é o que se pretende mostrar com
a contribuição brasileira dada por Willis Santiago Guerra Filho, segundo o qual, a
fenomenologia ofereceria a melhor preparação para a necessária superação do positivismo
formalista, sem recair em alguma forma igualmente já superada de jusnaturalismo.
Como estudioso do Direito em nosso país, Willis Santiago Guerra Filho encara como um
desafio o imperativo de renovação da ordem jurídica nacional, por ser totalmente nova a
base sobre a qual ela se assenta.
O empenho do Autor é re-interpretar o Direito Pátrio como um todo, à luz da Constituição
da República Federativa do Brasil , o que pressupõe uma atividade interpretativa da própria
Lei Fundamental, mas sem o ranço dos operadores jurídicos que não se dão conta do
modo objetivante como concebem o Direito, tal como se fosse uma máquina com a qual se
opera, quando se assim o fosse seriam eles as peças dessa engrenagem produtora de um
pseudo-saber, de caráter disciplinador. Admirador de Husserl, que prega nada haver de
conteúdo cognitivo nessa produção de saber, pois conhecimento, para ele, é evidência,
verdade, criadas a partir da intuição, inteira e completamente entendida, que se perde ao ser
rompido o elo com o domínio dos objetos sobre o qual deveríamos ser informados, nosso
Autor parte decididamente para o bom campo da verificação pré-científica, a fim de
valorizar o direito originário dessas evidências, antes desprezadas e, daí, poder-se buscar a
conexão essencial entre as ciências
|
| 34 |
The Man Who DisappearedNealon, Brian J. 19 August 2004 (has links)
No description available.
|
| 35 |
In the Shadow of Jim Crow: The Benching and Betrayal of Willis WardSteward, Tyran Kai 17 September 2013 (has links)
No description available.
|
| 36 |
A Pedagogy of Holistic Media Literacy: Reflections on Culture Jamming as Transformative Learning and HealingStasko, Carly 14 December 2009 (has links)
This qualitative study uses narrative inquiry (Connelly & Clandinin, 1988, 1990, 2001) and self-study to investigate ways to further understand and facilitate the integration of holistic philosophies of education with media literacy pedagogies. As founder and director of the Youth Media Literacy Project and a self-titled Imagitator (one who agitates imagination), I have spent over 10 years teaching media literacy in various high schools, universities, and community centres across North America. This study will focus on my own personal practical knowledge (Connelly & Clandinin, 1982) as a culture jammer, educator and cancer survivor to illustrate my original vision of a ‘holistic media literacy pedagogy’. This research reflects on the emergence and impact of holistic media literacy in my personal and professional life and also draws from relevant interdisciplinary literature to challenge and synthesize current insights and theories of media literacy, holistic education and culture jamming.
|
| 37 |
A Pedagogy of Holistic Media Literacy: Reflections on Culture Jamming as Transformative Learning and HealingStasko, Carly 14 December 2009 (has links)
This qualitative study uses narrative inquiry (Connelly & Clandinin, 1988, 1990, 2001) and self-study to investigate ways to further understand and facilitate the integration of holistic philosophies of education with media literacy pedagogies. As founder and director of the Youth Media Literacy Project and a self-titled Imagitator (one who agitates imagination), I have spent over 10 years teaching media literacy in various high schools, universities, and community centres across North America. This study will focus on my own personal practical knowledge (Connelly & Clandinin, 1982) as a culture jammer, educator and cancer survivor to illustrate my original vision of a ‘holistic media literacy pedagogy’. This research reflects on the emergence and impact of holistic media literacy in my personal and professional life and also draws from relevant interdisciplinary literature to challenge and synthesize current insights and theories of media literacy, holistic education and culture jamming.
|
Page generated in 0.0252 seconds