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Microbocais sônicos de diamante / Micro nozzles sonic diamond.Suelene Silva Mammana 06 June 2002 (has links)
Um método original para a fabricação de microbocais de diamante com perfil convergente-divergente foi desenvolvido neste trabalho. O método de fabricação desenvolvido utiliza deposição de diamante policristalino sobre moldes que posteriormente são removidos. Os moldes utilizados são fios de tungstênio submetidos a um processo de corrosão eletrolítica para gerar o perfil convergente-divergente de bocal. O microbocal de diamante foi fabricado para ser utilizado como controlador e medidor passivo de vazão de fluidos, quando operando em condições críticas de escoamento. Testes de vazão de gás foram realizados, utilizando os microdispositivos fabricados, para determinar os parâmetros de escoamento necessários para a utilização dos microdispositivos como controladores e medidores de vazão de gás. Os parâmetros críticos de escoamento, a saber, a vazão mássica crítica, a razão crítica de pressão e a vazão volumétrica crítica, bem cmo a faixa do número de Reynolds do escoamento e o coeficiente de descarga, foram determinados para todos os microdispositivos. A faixa de variação do número de Reynolds dos escoamentos obtidos foi de 1x10 POT.3-7x10 POT.4. Por exemplo, o microbocal de diamante com o menor diâmetro de garganta (16+/-1)x10mum apresentou vazão mássica crítica de (0,344+006)g/min, vazão volumétrica crítica de (314+/-5)cm POT.3/min e coeficiente de descarga de (1,27+/-0,19). Assim, foram fabricados com sucesso microbobais de diamante com perfil convergente-divergente e foram determinados os parâmetros críticos de escoamento que possibilitam a estes microbocais atuarem como controladores e medidores passsivos de baixo vazão de gás. / In this work an original method for the fabrication of diamond micronozzles with converget-divergent profile is presented. The method uses the deposition of polycrystalline diamond over a mold, which is subsequently removed. The referred molds are tungsten wires patterned by means of an electrolytic etching procedure in a way that the divergent-convergent profile is generated. The main motivation for producing such micronozzles is its application as passive flow controllers and flow meters elements when operating under critical flow conditions. The micronozzles produced here were tested in order to determine the critical flow parameters that are necessary for its operation, as passive flow controllers and flow meters elements. The critical flow parameters (critical mass flow rate, critical pressure ratio and critical volumetric flow rate), the Reynolds number range and the discharge coefficient were determined for all the microdevices produced. The Reynolds number for the microdevices was found to be in the range of 1x10 POT.3-7x10 POT.4. For instance, the diamond micronozzle with smaller throat diameter, (16+/-1)x10mum, presented critical mass flow rate of (0,344+0,006)g/min, critical volumetric flow rate of (314+/-5)cm POT.3/min and discharge coefficient of (1,27+/-0,19). Therefore, diamond micronozzles were successfully fabricated with convergent-divergent profile and the critical flow parameters necessary for its operation, as passive flow controllers and flow meters elements, were determined.
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"Todos na produção" : um estudo etnográfico das narrativas sônicas e raps em um bairro popular do sul do BrasilSantos, Luana Zambiazzi dos January 2015 (has links)
Este é um estudo etnomusicológico sobre as narrativas sônicas de uma Cohab, conjunto habitacional popular da Região Metropolitana de Porto Alegre/RS. Tais narrativas emergem das intersubjetividades de uma pesquisa etnográfica de rua e da escuta com o objetivo de compreender como seus habitantes interpretam a dimensão sônica e como ela dinamiza suas experiências urbanas. Dialogando com as tendências mais recentes dos Sound Studies, desde uma escala etnográfica do local ao “fora da norma”, discuto como a multiplicidade e a intensidade sonora vividas localmente estão imbricadas em narrativas globais em favor de uma diversidade cultural, retomando e gerando constrangimentos e conflitos nesse cenário popular urbano. Seguindo percursos dentro dessa multiplicidade, acompanho como a produção musical de rappers testemunha o cotidiano da cidade, descortinando conflagrações urbanas entre as escalas micro e macrossocial. Ao apontar um ethos sônico cohabeiro, busco transcender propostas teóricas anteriores com relação à esfera sonora e dialogar com aquelas mais contemporâneas da Etnomusicologia. / This is an ethnomusicological study on sonic narratives in a working class neighbourhood in the greater Porto Alegre area, Southern Brazil. These narratives arise from the intersubjectivities of a street ethnography aiming to understand how social actors listen to and interpret the sonic dimension and how it streamlines their urban experiences. In line with the latest trends of Sound Studies from an ethnographic scale of the local to the “awkward”, I discuss how the locals’ sonic multiplicity and intensity are embedded in global narratives in favor of a cultural diversity that resumes and generates constraints and conflicts in that urban scenario. Among this multiplicity, I followed rappers’ musical production that testifies the daily life of the city unveiling urban conflagrations. By pointing a “cohabeiro” sonic ethos, I intend to transcend previous theoretical propositions related to the sound level by itself and to dialogue with those more contemporaneous ethnomusicological perspectives.
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Desenvolvimento de um software em ambiente MATLAB para simulação de campo ultrassônico : Development of a MATLAB environment software for simulation of ultrasonic field / Development of a MATLAB environment software for simulation of ultrasonic fieldGasparini, Reynaldo Tronco 07 October 2012 (has links)
Orientador: Vera Lúcia da Silveira Nantes Button / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Elétrica e de Computação / Made available in DSpace on 2018-08-21T00:54:44Z (GMT). No. of bitstreams: 1
Gasparini_ReynaldoTronco_M.pdf: 4522453 bytes, checksum: a5e3883976604a06aa2fd8dcffb6cd3b (MD5)
Previous issue date: 2012 / Resumo: O estudo do campo acústico gerado por um transdutor ultrassônico é fundamental para sua construção e caracterização, pois permite prever qual será seu comportamento antes mesmo de ser construído e indica se ele realmente é viável para aplicação para a qual foi projetado, e se são necessárias modificações para que se comporte como o esperado. O presente estudo teve como objetivo o desenvolvimento de um software, em ambiente MATLAB®, para a simulação computacional de campos acústicos gerados por transdutores ultrassônicos de diferentes configurações, utilizando dois modelos que descrevem o campo, o de Zemanek e o de Stepanishen. Os campos de transdutores com focalização, apodização e meios com atenuação também poderão ser simulados. Para a simulação do modelo de Zemanek é utilizado o método matemático de discretização e para o de Stepanishen é empregada uma solução analítica para a resposta impulsiva de cada geometria de transdutor. As simulações foram validadas com resultados obtidos anteriormente por alunos do DEB/FEEC/UNICAMP e os programas desenvolvidos foram agregados em um pacote computacional. Estes programas têm seus códigos abertos para que futuramente sejam implementadas outras funções e configurações de transdutor. O software pode auxiliar no projeto de transdutores e também no estudo da modelagem do campo acústico pelos diferentes modelos que o descrevem / Abstract: The study of the acoustic field generated by an ultrasonic transducer is fundamental to its construction and characterization, because it allows to predict how it will behave before being built and whether it is really feasible or not for the application to which it was designed, and to suggest modifications to behave as expected. The present study describes the development of a software implemented in MATLAB®, for computational simulation of acoustic fields generated by ultrasonic transducers, of different configurations, using two models that describe the field, Zemanek and Stepanishen. Transducers with focusing, apodization and attenuation environment may also be simulated. For Zemanek's model simulation is used the mathematical method of discretization and for Stepanishen's model, an analytical solution for the impulse response of each transducer geometry is employed. The simulations were validated with results obtained previously by students from DEB/FEEC/UNICAMP and the developed programs were aggregated into a computer package. These programs have their code available so that, in a near future, other functions and transducer configurations can be implemented. The software can support the transducer design and also the study of the acoustic field modeling by different models that describe it / Mestrado / Engenharia Biomedica / Mestre em Engenharia Elétrica
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Propagation d'ondes de choc dans les milieux aléatoires avec des inhomogénéités distribuées dans l'espace ou dans une couche mince / Nonlinear shock waves propagation in random media with inhomogeneities distributed in space or concentrated in a thin layerYuldashev, Petr 10 November 2011 (has links)
Pas de résumé / Propagation of nonlinear acoustic waves in inhomogeneous media is an important problem inmany research domains of modern theoretical and applied acoustics. For example, studies onpropagation of high amplitude N-waves in turbulent atmosphere are relevant to the sonic boomproblem which involves high interest due to development of new civil supersonic aircrafts. Inrelation to sonic boom problem, many studies on spark-generated N-wave propagation through aturbulent layer were carried out in model laboratory-scale experiments which are more controlledand reproducible than field measurements. Propagation of high intensity focused ultrasound intissue (HIFU) is intensively studied for medical applications. HIFU is a basis of new surgicaldevices for noninvasive thermal and mechanical ablation of tumors.In this thesis, the problem of characterization of high amplitude N-waves generated in air byan electric spark was studied using combined acoustical and optical methods. The fine structureof shocks was deduced from the shadowgraphy images with a resolution that cannot be obtainedusing condenser microphones. It was shown that the combination of optical and acoustical methodsallows complete characterization of the N-waves.N-wave propagation through a layer of thermal turbulence was further studied in a laboratoryexperiment. The evolution of statistical distributions and average values of the most importantN-wave parameters was investigated at different propagation distances. Experimental results werecompared to data obtained in another experiment known in literature, where N-wave was propagatedthrough kinematic turbulence. It was shown that in the case of almost the same widths ofthe turbulent layers, values of the characteristic scales and rms of refractive index fluctuations, thekinematic turbulence leads to stronger distortions of the peak pressure and the shock rise time ofthe N-wave and to 2-3 greater probabilities to observe intense focusing in caustics.Effects of nonlinear propagation and random focusing on the statistics of N-wave amplitudewere studied theoretically using the KZK equation and the phase screen model. The phase screenwas characterized by the correlation length and the refraction length – the distance where firstcaustics occur. Probability distributions, mean values and standard deviations of the N-wave peakpressure were obtained from the numerical solutions and were presented as functions of the propagationdistance and the nonlinear length. Statistical results from the KZK model were comparedwith analytical predictions of the nonlinear geometrical acoustics approach (NGA). It was shown,that NGA approach is valid only up to the distance of one third of refraction length of the screen.Strong nonlinear effects were shown to suppress amplitude fluctuations. The effect of the scale ofinhomogeneities on amplitude statistics was also investigated.The problem of focusing of ultrasound beam through inhomogeneous medium is importantfor medical diagnostics and nondestructive testing problems. The inhomogeneities of biologicaltissue or of industrial materials can destroy beam focusing. In the thesis, distortions of a weaklynonlinear diagnostic beam focused through a phase layer of special configuration were consideredexperimentally and theoretically. Feasibility of selective destruction of focusing of differentharmonics in the beam was predicted in the modeling and confirmed in experiment.The most modern HIFU devices rely on using two-dimensional multi-element phased arrayswith elements randomly distributed over a segment of a spherical surface. Numerical experimentis an important tool to characterize pressure fields created by HIFU radiators. Intensity levels atthe focus of HIFU radiators can reach several tens of thousands of W/cm2, causing nonlinearpropagation effects and formation of shocks [...]
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Úloha rudimentárních struktur v odontogenezi. / The role of rudimentary structures in odontogenesis.Lochovská, Kateřina January 2017 (has links)
In vivo organogenesis is based on the temporal-spatial developmental processes that depend on cell behaviour, for example on their growth, migration, differentiation and intercellular interactions. Such behaviour is regulated by appropriate transient expression of various signalling molecules. Despite the significant advances in therapeutic strategies, the secret of the development of the biological replacement of a damaged or missing tooth has not yet been revealed. In this context, animal models provide a powerful tool for studying tooth normogenesis and pathogenesis in both basic and applied research. Early development of the tooth shares similar morphological and molecular features with other ectodermal organs. At the same time, these features are largely preserved also between species, which is advantageous for the use of model organisms. The dental formula of both: the human and the mouse are reduced against a common ancestor, but both groups of organisms evince simple as well as multicusped teeth. In both, structures called rudimentary were found. These structures are suppressed during ontogenetic development and generally they are not attributed to essential functions. That is why we aimed to study dental rudiments in detail and reveal their function in odontogenesis. This work presents new...
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SOUNDMAT : A Sonic and Kinesthetic Tool for ArchitectsNikoli, Maria January 2021 (has links)
This thesis project aims to bring together knowledge and methods from embodied interaction design in order to help architects expand their current repertoire of sketching tools and methods. As argued by Bernard Tschumi (1996) and Juhani Pallasmaa (2012), architecture is a sight-dominated design field, and architects are faced with the paradox of having to design embodied, multisensory experiences with visual means and from a disembodied perspective. Situated in the genre of physical computing, the outcome of this thesis is the prototype of a sensor-based tool for sketching with sound and kinesthesia. The prototype is primarily targeted to architects, but may also be of interest to professionals from other fields who are involved in space-making, such as interaction designers, artists, scenographers, and interior designers, among others. The findings of this thesis intend to contribute to the field of interaction design, and especially the subfield of embodied interaction. This thesis addresses the aforementioned problem domain, which was first identified when I practiced the profession of architecture, and then further understood during this project, namely during literature review and user research. Building upon three main areas of theory, this project finds its grounding in embodied interaction theory, phenomenological concepts, as well as a contemporary view of the soma as a united self of mind and body. Fieldwork was a very important part of the process, and methods such as interviews, surveys, and cultural proves were employed to ground the project in user research. Ideation mainly consisted of sketching with embodied methods. Lastly, the user testing of a Wizard-of-Oz prototype was essential in assessing and evaluating the final design.
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Ljud som konstnärlig metod : En analys av sonisk estetik och politik i Lawrence Abu Hamdans ljudverk Saydnaya (the missing 19db)Tawaifi, Anjel January 2019 (has links)
The aim of this essay is to study the political and aesthetical qualities in Lawrence Abu Hamdans sound piece. In Saydnaya (the missing 19db) former detainees from the infamous Syrian prison Saydnaya are interviewed about the many sounds, silences and emotions that circulated in the prison. Since they were kept in total darkness during their stay in Saydnaya, their memories and impressions are sonic. The piece can therefore be called a sonic testimony and the detainees are referred to as earwitnesses. The methodological framework of this study is outlined by Salomé Voegelin in her book Listening to Noise and Silence. In the core of this method lies the notion of deep listening (also called sonic sensibility). From listening noise and silence naturally unfold. In order to define and discover the affects of the artwork and its sonic material, the theoretical work of Gilles Deleuze, Brian Massumi and Sara Ahmed is applied. More specifically the concepts of lines of flight and affect. Emotions and sound seem to blend in the most peculiar ways. This essay is just a suggestion of how that blend might look... or should I say sound? And most importantly this essay will investigate how these non-visual forces work, stick and flow. How they can be used and what they produce. Some of the questions that this essay will touch upon are: what are the sonic affects that this artwork produces? And how does the artist use noise and silence in the construction of Saydnaya?
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Kan referenslåtar vidga mina vyer? : Ett arbete som analyserar referenslåtar för att implementera nya kunskaper i låtskrivandet / Could reference tracks expand my horizons? : Implementing new knowledge into songwriting by reference tracks analysisSandström, Anton January 2022 (has links)
Min tanke med detta arbete var att hitta nya sätt att både skriva och producera låtar på, genom att använda mig av referenslåtar som inspirationskälla. Jag fokuserade på tre olika beståndsdelar från referenslåtarna, som sedan implementerades i tre nyskapade demolåtar. I låt 1 fokuserade jag på basen roll. I låt 2 fokuserade jag på solosångens relation till körsång och i låt 3 fokuserade jag på elpianot Fender Rhodes. När jag analyserade referenslåtarna så tog jag med mig vissa principer från respektive referenslåt och implementerade i mina egna låtar. Detta resulterade i att jag bland annat upptäckte nya spelsätt, sound och produktionstekniker att inspireras av till mina tre nyskrivna demolåtar. Att jobba med referenslåtar upplevde jag var ett bra startskott för att komma igång med låtskrivarprocessen. Samtidigt kunde jag stundtals känna mig begränsad och låst till referenslåtarna. Trots detta så var det en väldigt lärorik metod som hjälpte mig at vidga mina vyer och möjliggjorde för mig att skapa tre demolåtar som jag kanske inte annars hade skrivit.
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DESIGNING FOR THE IMAGINATION OF SONIC NATURAL INTERFACESKnudsen, Tore January 2018 (has links)
In this thesis I present explorative work that shows how sounds beyond speak can be used on the input side in the design of interactive experiences and natural interfaces. By engagingin explorative approaches with a material view on sound and interactive machine learning, I’ve shown how these two counterparts may be combined with a goal to envision new possibilities and perspectives on sonic natural interfaces beyond speech. This exploration has been guided with a theoretical background ofdesign materials, machine learning, sonic interaction design and with a research through design driven process, I’ve used iterative prototyping and workshops with participants to conduct knowledge and guide the explorative process. My design work has resultedin new prototyping tools for designers to work with sound and interactive machine learning as well as a prototypes concept for kids that aims to manifest the material ndings around sound and interactive machine learning that I’ve done in this project.By evaluating my design work in contextual settings with participants, I’ve conducted both analytical and productive investigations than can construct new perspectives on how sound based interfaces beyond speech can be designed to support new interactive experiences with artefacts. Here my focus has been to engage with sound as a design material from both contextual and individual perspectives, and how this can be explored by end-users empowered by interactive machine learning to foster new forms of creative engagement with our physical world.
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HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating expression and secretion of Sonic hedgehog / HIF-1はソニックヘッジホッグの発現と分泌を亢進し、膵臓がん細胞とがん間質線維芽細胞の機能関係を調節するKatagiri, Tomohiro 23 May 2018 (has links)
京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第21257号 / 医博第4375号 / 新制||医||1029(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 増永 慎一郎, 教授 妹尾 浩, 教授 松田 道行 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM
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