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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
611

Understanding cellular differentiation by modelling of single-cell gene expression data

Papadopoulos, Nikolaos 08 August 2019 (has links)
No description available.
612

Kartläggning av olika testdatahanteringsverktyg : Jämförelse och utvärdering av olika testdatahanteringsverktyg

Viking, Jakob January 2019 (has links)
Due to new regulation GDPR, a whole industry had to change its way of handling data. This industry is the test data management industry, an industry that bases its products on managing PII (Personally Identifiable Information). This leads to an increased demand to how data is stored, which by its own leads to different solutions and several companies that try their chances to establish themselves in this market. The overall purpose of this study is to extract the good and bad aspects from five different test data management tools. In addition to the collection of fact, tests are performed to gain experience with each program to later summarize them both. The result consists of the result from the test cases and the result from the comparison matrix and together they form the grade on the test data management tool. The conclusion that can be drawn from this mapping is that the programs with the highest flexibility have a greater chance of success, but there are also simple programs that show that simplicity is at least as important. / På grund av den nya förordningen GDPR var en hel bransch tvungen att ändra sitt sätt att hantera data på. Denna bransch är testdatahanteringen, en bransch som baserar sina produkter på att hantera PII (Personally Identifiable Information). Detta leder till ett ökat krav på hur data förvaras leder till olika lösningar och flera företag som tar chansen att etablera sig i marknaden. Det övergripande syftet i denna undersökning är att ta fram de positiva och negativa aspekterna ur fem olika testdatahanterare. Utöver bara faktainsamling utförs tester för att få erfarenhet med varje program och därefter sammanfatta åsikterna med konkreta fakta. Resultatet består av resultatet från testfallen och resultatet från jämförelsematrisen och tillsammans bildar de ett betyg på testdatahanteringsverktyget. Den slutsats som kan dras från denna kartläggning är att de program med högst flexibilitet har större chans att lyckas men även finns det enkla program som visar att simpelhet är minst lika viktigt.
613

Development of Fluidity Measurement Technique and Automation of Measurement Station : Developing the existing Fluidity Measurement Station by automating the operation and measuring the fluidity digitally with MATLAB Image Processing Tools. / Utveckling av Fluiditsmätningsteknik och Automatisering av Mätstation

Ullal, Pratheek January 2019 (has links)
Bryne AB has invented a device called Loop for measuring the fluidity of molten metal. Loop is made up of refractory fiber material and has a dimension of 196 sq.mm within which there is an engraved spiral shaped runway for the molten metal to flow. The distance traveled by the molten metal in the spiral determines its fluidity and is measured visually by the operator with the help of the spiral scale printed on the Loop. A workstation is used to support the Loop for an easier and better working environment. At present, the entire operation of fluidity measurement is done manually. The aim of the thesis is to develop an automatic workstation for the fluidity measurement and find a technique to measure the fluidity without human visual aid. Further, an attempt has been made to find a way to store and retrieve the measured values for future use.   The automation of the workstation is done with the help of Arduino Uno circuit board for electrical connections and Arduino IDE for programming the circuit. MATLAB image processing tool is used for measuring the fluidity digitally.   The prototype of the automated workstation is built and showcases the ability to reduce the time and operational errors. The automation of the unplugging operation saves up to 7 seconds.  The digital measuring of the fluidity with FLIR thermal camera and MATLAB image processing tool does not show significant improvement in accuracy in measurement, but it reduces the dependency on the expertise of the operator. There is an error of 12.7% from the actual fluidity value.
614

ABW-KONTOR: FÖRSLAG TILL ETT KOMMUNIKATIONSVERKTYG FÖR ATT EFFEKTIVISERA UTFORMNINGSPROCESSEN / ABW-OFFICES: SUGGESTION FOR A COMMUNICATION TOOL TOWARDS A MORE EFFECTIVE DESIGN PROCESS

Törnvall, Marcus, Stendlert, Ellinor January 2019 (has links)
Syfte: Idag har det blivit allt mer vanligt att verksamheter använder sig av aktivitetsbaserade kontor, så kallade ABW-kontor. En anledning till detta är att kontorsformen är mer yteffektiv då den oftast är utformad för ett färre antal medarbetare än vad verksamheten har anställda. Problemet med många av dagens aktivitetsbaserade kontor är att utformningen inte är rätt anpassad till verksamhetens behov. Detta grundar sig i att det finns en kommunikationsbrist i utformningsprocessen vilket medför att arkitekten inte får den information om verksamheten som behövs. Målet med arbetet har varit att komma fram till ett hjälpmedel som kan undvika kommunikationsbristen för att i framtiden ge arkitekter ett bättre underlag för att utforma ABW-kontor. Metod: Studien har bestått av en kvalitativ undersökning där fallstudier, intervjuer och dokumentgranskning använts. Studiens största datainsamling består av semistrukturerade intervjuer med arkitekt och personer som arbetat hos de tre verksamheterna under utformningsprocessen. Utöver detta utfördes en dokumentgranskning av planlösningarna hos verksamheterna. Dessa datainsamlingsmetoder kunde därefter analyseras och generera svar på studiens frågeställningar. Resultat: Undersökningen visade att det funnits en kommunikationsbrist i samtliga utformningsprocesser hos de tre verksamheterna. En av verksamheterna hade använt sig mer av medarbetarna i utformningsprocessen vilket kan kopplas till att de anställda var nöjda med kontoret. Från intervjuerna framgick det vad i kontorets utformning som var viktigt för att kontoret skulle bli så anpassat till verksamhetens behov som möjligt. Utifrån den här informationen skapades en checklista för arkitekt, beställare och anställda. Checklistan kan användas i utformningsprocessen för att få ett bra underlag till att anpassa kontorets utformning till verksamhetens behov. Konsekvenser: En slutsats av den här studien är att alla ABW-kontor inte är anpassade efter verksamhetens behov. Under utformningsprocessen involveras inte alla medarbetarna tillräckligt mycket vilket har visat sig vara nödvändigt för ett fungerande resultat. För att ge en arkitekt möjlighet att utforma ett aktivitetsbaserat kontor så bra som möjligt behövs information från medarbetarna som förklarar deras arbetssätt och behov. En rekommendation utifrån resultatet är att göra checklistan digitaliserad så att större företag kan använda sig av den också. Begränsningar: Studien har avgränsats till att undersöka tre verksamheter med olika typer av organisationer, ekonomi, IT och marknadsföring. Antalet intervjuer på de olika verksamheterna har även avgränsats till att intervjua personer som endast varit med under bytet till ABW-kontor. Den resulterande checklistan är lämpad att användas i små företag eftersom checklistan är i pappersform. För stor insamling av checklistor kan minska effektiviteten i utformningsprocessen. Metodvalen är anpassade för studiens omfattning men arbetet hade stärkts om intervjuer även utförts med arkitekter som utformat de valda ABW-kontoren. Nyckelord: ABW, Aktivitetsbaserat kontor, Kommunikationsverktyg, Utformningsprocess. / Purpose: Nowadays it is more common to use activity based work offices, known as ABW-offices. One of the reasons why it is getting more popular is because of the space efficiency. ABW-offices are often designed for less people than number of employees. The problem with many of today’s activity based work offices is that it is not suitable for every type of work environment and its needs. The reason is lack of communication during the design process. That can lead into less information about the working environment for the architect. The goal with the case study has been to produce a userfriendly communication tool so the architect has a better base to start the design process. Method: The study is a qualitative survey with case studies, interviews and document analysis. The largest data collection has been semi structured interviews with architect and employees. The document analysis is based on the layouts of the different work offices. These data collection methods could thereafter be analyzed and generate answers to the questions of the case study. Findings: The study showed that there has been a lack of communication during the design process in every ABW-office. One of the three offices involved the employees during the design process, and the employees seemed to be happy with how the office turned out. The interviews gave information about what factors that can be most important to make the ABW-office as suitable as possible for the work office. After analyzing the empiricism a checklist was created for architect, client and employees. The checklist can be used during the design process to fill the client and the employees need to make a suitable working environment. Implications: A conclusion of this study is that all ABW-offices are not suitable enough for the work office. All the employees did not get fully involved during the design process which, after research, are the best way to get the ultimate result. Therefore, the architect needs to get as much information as possible from the employees to make a good and suitable layout for plan views. A recommendation is to improve the checklist and make it digitized so bigger companies can use the checklist too. Limitations: The study has been delimited to make a research about three different companies with different types of organizations, economy, IT and marketing. People that has been interviewed have all been a part of the exchange to an ABW-office. The checklist is mostly suitable for smaller companies to use since the checklist is in shape of paper. Too many checklist can lead to a less effective designprocess. The methods are chosen in consideration to time and extent of the study. The study would have strengthen if more interviews with for instance the responsible architects of the chosen ABW-offices were made. Keywords: ABW, Activity based work office, Communication tool, Design process.
615

Estudo epidemiológico da distribuição das mortes de pacientes traumatizados num hospital universitário de referência terciária com avaliação dos atendimentos por painel de revisão de óbitos e dados de autópsiasatendimentos por painel de revisão de óbitos e dados de autopsias / The hole of autopsies in the current medical education

Marino, Roberto 19 March 2019 (has links)
As autópsias sempre foram consideradas como um exame de grande valia para o diagnóstico da real causa de morte dos pacientes, avaliação da eficácia do tratamento empregado e como importante ferramenta para o ensino médico. Durante as últimas décadas, houve um declínio importante na realização do número de autópsias acadêmicas, em grande parte pela desmotivação pela equipe profissional ao solicitá-la e realiza-la (clínicos e patologistas), justificando ser algo ultrapassado e de pouca validade, perda de interesse pelos alunos também, fatores culturais, religiosos, econômicos e de comportamento de familiares. Este estudo visa analisar a importância das autópsias como importante instrumento de ensino médico, desvendar os reais motivos pela sua decadência nas universidades, quais as consequências no futuro para a formação médica e medidas que podem ser tomadas para reverter esse processo de desvalorização do exame / Autopsies have always been considered as a valuable test for diagnosis ofthJ cause ofdeath of patients, evaluation ofthe efficacy ofthe treatment used an important tool for medical teaching. During the last decides, there has been.l decline in the number ofacademic autopsies, largely due to the lack of motim the professional team when requesting and performing them(clini=ans and consequentes for medical training and what steps can be taken to reverso th devaluation ofthe exam
616

The recent development of South African short film making

Archer, Nicholas Paul 15 November 2006 (has links)
Student Number : 9905214K - MA research report - School of Dramatic Art - Faculty of Arts / South Africa’s film industry presently has huge, unrealised potential for growth. Currently one of the most vibrant sectors of the local industry is short filmmaking. This research’s main contention is that, for a number of reasons the short form is the most viable form for film-making development to take. The short film’s value as a training tool and essential building block for local film-making is scrutinized. To this end the research incorporates a content and form analysis of selected short films, with special reference made to the modes and economic conditions of production that affect the film industry. To conclude, I take the position that film-making, as a form of artistic and cultural dialogue, has tremendous possibilities for the development of a national identity, the creation and perpetuation of local myths and the fostering of social cohesion. For these reasons the short form is worthy of more concerted institutional support.
617

De l’épidémiologie moléculaire aux analyses fonctionnelles de Brucella chez les ruminants, une approche intégrée pour l’identification et l’étude de la diversité phénotypique d’un genre génétiquement homogène / From molecular epidemiology to functional analysis of Brucella in ruminants, an integrated approach for the identification and the study of the diversity of phenotypes of a genetically homogenous genus

Holzapfel, Marion 26 November 2018 (has links)
La brucellose est une zoonose causée par le genre bactérien Brucella (B.) dont l’incidence mondiale est estimée à 500 000 cas humains par an. Le réservoir est animal, touchant principalement les espèces de rente. Les espèces les plus importantes pour l’Homme sont B. melitensis, B. abortus et B. suis qui partagent plus de 90% d’identité de séquence. Bien qu’elles soient très apparentées sur le plan génétique, elles présentent une diversité de caractéristiques phénotypiques, de préférence d’hôte et de pathogénicité. L’homogénéité génétique de ces espèces peut apparaître comme un atout pour le développement d’outils de diagnostic universels robustes. En revanche, il s’agit d’un challenge pour les distinguer, rendant difficile la caractérisation précise des isolats issus d’un même foyer. Dans le cadre de cette thèse, un outil de diagnostic moléculaire de PCR en temps réel ciblant le genre Brucella a été développé et optimisé. L’outil a été évalué sur des prélèvements de lait de ruminants, ces prélèvements peuvent être une source importante de Brucella et peuvent être utiles au dépistage de la maladie à l’échelle du troupeau. Basée sur la détection de l’élément d’insertion IS711, une séquence présente en plusieurs exemplaires dans le génome, cette méthode affiche des valeurs de sensibilité et de spécificité qui la rendent intéressante pour un schéma global de lutte contre la brucellose. D’autre part, en vue d’améliorer la compréhension de la stabilité génétique de B. melitensis, un panel original de souches isolées dans le cadre d’un foyer et impliquant 4 espèces d’hôtes différentes a été comparé. Ainsi à l’aide de différentes approches complémentaires, leurs séquences génomiques, les caractères phénotypiques ainsi que leurs comportements dans un modèle in vitro ont été comparés. Nos résultats n’ont pas mis en évidence marqueurs qui laisserait à penser que des mutations dans le génome soient indispensables pour s’adapter à un nouvel hôte / Brucellosis is a zoonotic disease caused by the bacterial genus Brucella (B.), whose global incidence is estimated at 500,000 human cases per year. The reservoir is animal, affecting mainly livestock. The most important species for humans are B. melitensis, B. abortus and B. suis, which share more than 90% sequence identity. Although highly genetically related, Brucella spp. exhibit a variety of phenotypic characteristics, host preference and pathogenicity. The genetic homogeneity of these species may appear as an asset for the development of robust universal diagnostic tools. On the other hand, it is a challenge to distinguish them, making it difficult to precisely characterize isolates from the same outbreak. As part of this thesis, a real-time PCR molecular diagnostic tool targeting the genus Brucella was developed and optimized. The method has been evaluated on ruminant milk samples; these samples may be an important source of Brucella and may be useful for herd-scale disease screening. Based on the detection of the IS711 insertion element, a sequence present in several copies within the genome, this method displays sensitivity and specificity values that make it interesting for a global scheme to fight against brucellosis. On the other hand, in order to improve the understanding of the genetic stability of B. melitensis, an original panel of strains isolated in an outbreak and involving four different host species was compared. Thus, using different complementary approaches, their genomic sequences, phenotypic characteristics and their behavior in an in vitro model were compared. Our results did not highlight markers that would suggest that mutations in the genome are essential to adapt to a new host
618

”Värdegrund ... det är väl bra om alla i samhället ändå drar åt samma håll.” : – effekterna av filosofiska samtal i ett högstadieklassrum. / ”Value foundation ... wouldn’t it be good if everyone in the society pulled in the same direction” : – the effects of philosophical conversations in a high school classroom.

Karlsson, Isabella January 2019 (has links)
Mitt arbete tog sitt avstamp utifrån en aktionsinsats i mitt arbetslag, där vi tyckte oss se att värdegrunden hos våra elever inte längre var självklar och att de uppvisade tecken på intolerans och brist på empati osv. Syftet med mitt arbete var att se vilka effekter en intervention med filosofiska samtal kunde ha på elevernas samtals- och argumentationsförmåga, samt för deras förståelse för värdegrundsfrågor. Frågeställningarna handlade om vilken effekten var enligt ett metodverktyg för samtal, enligt eleverna själva, samt utifrån mina egna observationer. Eleverna gick i årskurs 7 och jag använde mig av semistrukturerade pre- och postgruppintervjuer, observationer enligt the Argumentation Rating Tool (ART), samt mina egna fältanteckningar utifrån observationerna. Samtalen pågick under vårterminen 2019 och genomfördes vid 10 tillfällen. Jag kom fram till att de filosofiska samtalen hade haft god effekt på elevernas sätt att argumentera och samtala, både enligt elevernas egen uppfattning, bedömningarna i ART och mina egna fältanteckningar av observationer, trots den begränsade tid de pågick. Elevernas förmåga att samtala kring värdegrundsfrågor hade också utvecklats, vilket tyder på en större förståelse för demokratibegreppen, än innan interventionen.
619

Study on the machinability and surface integrity of Ti6Al4V produced by Selective Laser Melting (SLM) and Electron Beam Melting (EBM) processes / Pas de titre fourni

Milton, Samuel 28 May 2018 (has links)
Les technologies de fabrication additive(FA) basées sur la technique de fusion laser sur lit de poudres, telles que les procédés de fusion sélective laser (Selective Laser Melting ‘SLM’) et de fusion par faisceau d'électrons (Electron Beam Melting ‘EBM’), ne cessent de se développer afin de produire des pièces fonctionnelles principalement dans les domaines aérospatial et médical. Le procédé de fabrication additive offre de nombreux avantages, tels que la liberté de conception, la réduction des étapes de fabrication, la réduction de la matière utilisée, et la réduction de l'empreinte carbone lors de la fabrication d'un composant. Néanmoins, les pièces obtenues nécessitent une opération d’usinage de finition afin de satisfaire les tolérances dimensionnelles et l’état de surface. / Additive Manufacturing (AM) techniques based on powder bed fusion like Selective Laser Melting(SLM) and Electron Beam Melting processes(EBM) are being developed to make fully functional parts mainly in aerospace and medical sectors. There are several advantages of using AM processes like design freedom, reduced process steps, minimal material usage and reduced carbon footprint while producing a component. Nevertheless, the parts are built with near net shape and then finish machined to meet the demands of surface quality and dimensional tolerance.
620

The language introduction program in Sweden : How is translanguaging used in English education?

Bourada, Rim January 2019 (has links)
This degree project focuses on the English classroom in the Swedish language introduction program, more specifically on the use of translanguaging as a teaching tool for newly arrived students. This thesis is an attempt to better understand the classroom dynamics in the program during English lessons by answering the following questions: What are the challenges of teaching English in the language introduction program in Sweden? What do teachers think about translanguaging as a teaching tool in the language introduction classes? Is using it taking advantage of pre-existing knowledge? The research was conducted with three teachers from one school in central Stockholm, all coming from different socio-cultural backgrounds and having varying degrees of experience as teachers. The data was gathered through classroom observations and interviews, which allowed for triangulation, thus offering a better understanding and a deeper view of their teaching practices. Three lessons were observed, one with each teacher. These observations were conducted prior to the interviews, to facilitate the comparison between the teaching styles of each teacher. Doing so allowed for more exhaustive and informative interviews. Although the qualitative nature of the data does not allow for the results to be generalizable, triangulation does give the results legitimacy and transferability. The results of this research will be beneficial in understanding how to tackle a multilingual environment, given that that is the direction in which Sweden is heading.

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