根據2009年IMS生物技術開發中心統計，國內藥廠前十大銷售排名均為外商企業，且在健保藥品給付進口外國藥廠的購買金額也高達70%。由此可見外商製藥公司在台灣藥品市場所佔有的舉足輕重地位。而以往有關製藥產業的論文研究中，較多著重於其行銷業務、策略以及研發模式等方面的分析，很少針對製藥公司的知識管理來加以探討。就知識密集的製藥業來說，此為明顯的研究缺口，因此，本研究以製藥產業為主軸，選定在台灣藥品市占率高的外商藥廠為研究對象，探討其知識管理作為，以及知識管理影響因素如何影響知識管理活動。 本研究同時從知識管理影響因素與知識管理活動兩構面來探討我國外商藥廠的知識管理。研究方法上採用多重個案研究法，研究者首先結合研究問題與文獻回顧，結果導出實證研究的觀念性架構，再以此理論觀念模式為主軸進行個案的訪談與資料的收集，實地深入訪談四家我國外商藥廠，瞭解其知識管理影響因素以及知識管理活動主要作為。 本研究所得到的結論如下： 1. 外商藥廠的知識管理目標若越明確、且與人員的工作流程結合度越高，則其知識蓄積活動越容易進行，且知識保護活動也越能確實執行。 2. 外商藥廠會透過企業內部環境的建構，來促進其知識的擴散。 3. 外商藥廠的科技設備若越完備，則其知識蓄積越容易進行，也因而強化了其知識的創造與擴散。 4. 外商藥廠的績效評估制度之設計與衡量指標之搭配，有助於其知識創造及知識擴散的進行。 5. 外商藥廠知識的結構化程度會影響知識蓄積以及擴散方式。知識的結構化程度越高，則越容易透過文件式的蓄積方式、並經由資訊系統來擴散知識；而知識的結構化程度越低，則越容易透過人員式的蓄積方式、並仰賴面對面接觸來擴散知識。 6. 外商藥廠會藉由成功經驗的分享，來創造組織與各部門的知識，也因而促進了知識的擴散。 7. 外商藥廠會藉由師徒制度來擴散經驗型的知識。 8. 外商藥廠會積極主動並重視知識保護的活動，且使之成為日常作業流程的一部分。 本論文最後說明本研究結果在學術上的貢獻，同時對實務研究上與後續研究上提出一些建議。 / According to IMS Health Global Pharma Forecast in 2009, the top ten sales volumes of pharmaceutical enterprises in Taiwan are all international enterprises. Under the National Health Insurance reimbursement, the international enterprises occupy only 30% of all the pharmaceuticals volumes, but occupy up to 70% of all the pharmaceuticals sales, which shows that the international pharmaceutical enterprises play a decisive role in Taiwan pharmaceutical market. Most of the past studies of pharmaceutical industry focus on the aspects of marketing, strategy, and research and development. Few specifically inrestigate the issues of knowledge management and knowledge management influential factors. Consequently, a research gap can be found as pharmaceutical industry in a knowledge-intensive one. This research focuses on the pharmaceutical industry, explores the knowledge management activities of international pharmaceutical enterprise in Taiwan from both the view of knowledge management influential factors and knowledge management activities, and aims to discover the key factors that influence knowledge management. This research adopts four international pharmaceutical enterprises in Taiwan as case studies and conducts interviews with managers to understand knowledge management influential factors and knowledge management activities. By knowing inside information of knowledge management of the four companies, this research can deliver a more practical and well-organized point of view, giving examples and facts to the future implementation of knowledge management for Taiwan pharmaceutical enterprise. The conclusions of this research are as bellow. 1. The clearer of the goal in knowledge management and the stronger of connection to the daily process in the company allow knowledge researving and protection activities implemented. 2. Higher level of organization cooperation and sharing culture leads to higher level of reliance of knowledge among each department, facilitating knowledge to spread more effectively in the company. 3. The completeness of technolocial facilities helps knowledge researving activities more convenient, knowledge creation activities more smoothing , and knowledge difussion activities more efficient. 4. The design of performance appraisal influences the knowledge creation and knowledge difussion activities. 5. The degree of knowledge structure influences the knowledge researving and difussion activities. 6. Sharing the best practice ficilitates knowledge creation and knowledge difussion activities . This method had gradually become a well-known practice in international pharmaceutical enterprise. 7. 「Mentor program」 is an important way to extend experienced knowledge. Each company has different approach to conduct 「Mentor program」. 8. The knowledge protection activity includes intellectual property rights、information system、contracts、data reserved management and data destroyed process, and the degree of compulsory execution is in accordance with the principles of the companies.

新藥研發是台灣生技發展的重點產業。新藥研發一般具有高投資、高風險與研發期長的特性。因此，有些公司會透過多角化的策略來分散風險。不過，在有限的資源與人力下，發展多角化的產品通常是個極具挑戰的任務。因此，本研究針對新藥研發公司，就其採取多角化的動機與策略來加以探討。 此外，在知識經濟的時代，知識已成為企業最重要的資產，如何透過有效的知識管理以提昇組織知識的價值，則是企業所重視的關鍵性議題之一。新藥研發屬知識密集產業，知識管理對於公司相當重要。因此本研究亦從知識特性的觀點（路徑相依度、不確定程度與競爭衝擊程度）來探討其對知識管理的影響。 本研究在方法上採取多重個案研究的方式，透過深入個案訪談與次級資料收集，所得到的結論如下： 1. 台灣新藥研發公司選擇多角化策略的動機相當多元。 2. 台灣新藥研發公司多角化的動機與多角化目標領域之路徑相依度有關。 3. 台灣新藥研發公司多角化目標領域技術知識的路徑相依度與競爭衝擊程度會影響其技術知識吸收的方式。 4. 台灣新藥研發公司多角化目標領域技術知識的路徑相依度會影響其組織設計、分工與人員式知識擴散的對象。 5. 台灣新藥研發公司進行多角化產品研發時，其知識蓄積活動上傾向於採取「機械-整合式」的蓄積方式。 / New drug development industry is one of the key biotech development areas in Taiwan. The nature of new drug development involves high investment, high risk and long development time. As a result, some companies develop diversification as a strategy to reduce the risk. However, the scarcity of resource and manpower makes developing diversified products particularly challenging. This study would focus on why these companies choose diversification strategy and which strategies they develop. Knowledge management is very important for companies in research-intensive industry. This study would also explore how the companies practice knowledge management on its diversified projects. In addition, this study uses technological knowledge characteristics (path dependence, degree of uncertainty, and competitive position) to analyze the effect upon knowledge management process. In this study, multiple case study method to take the way through in-depth case interviews and secondary data collection, the conclusion is as follows: 1.The reasons why new drug development companies in Taiwan underwent diversification vary a lot. 2.Synergy motivation of new drug development companies in Taiwan will affect the path dependence of technological knowledge in target areas for diversification. 3.Path dependence and competitive intensity of technological knowledge in target areas for diversification will affect the way of technical knowledge acquired in Taiwan’s new drug development companies. 4.Path dependence of technological knowledge will affect the organizational design, the division of labor and object of personnel-type knowledge diffusion 5.New drug development companies in Taiwan tend to choose 「Mechanical-Integrated」mode of knowledge Storage when the diversification activities.

摘 要 本研究主要是藉由探討台灣企業在面臨「轉型升級壓力」而必須做經營策略調整時，經由本研究所建構的理論模型與實際個案間的檢證研究突顯出「企業學習能力」在企業轉型升級與策略選擇過程中的關鍵地位。 本研究以創造台灣最高經濟產值貢獻的資訊科技(IT)產業之個案廠商為對象，探究其「企業學習能力」對「企業轉型升級策略」選擇的影響，以及「目標產業的知識特質」、「企業學習能力」、「企業轉型升級壓力」三者間的關聯性。本論文的研究方法是以對個案的資料文件做深度探究的內容分析法為主，選取國內具代表地位的二家資訊硬體大廠為研究對象，嘗試對其「企業學習能力」與「企業轉型決策過程」作系統性的探索。 本研究歸納分析所得到的研究發現如下： 【研究發現一】取得「企業學習能力」的實證觀察指標。 【研究發現二】「企業轉型升級壓力」的大小會影響「企業轉型升級策略選擇」。壓力愈小時，企業選擇「攻勢」之轉型升級的機會就愈大；反之，則企業選擇「守勢」之退守退出的機會就愈大。 【研究發現三】「企業學習能力」的強弱會影響「企業轉型升級策略的選擇」。企業學習能力愈強時，則企業選擇「攻勢」之轉型升級的機會就愈大；反之，則企業選擇「守勢」之退守退出的機會就愈大。 【研究發現四】「企業學習壓力數學關係式」的發現實證了「企業學習能力」與「目標產業知識特質」和「企業轉型升級壓力」之間，存有簡單的「數學關聯」。 【研究發現五】「企業轉型升級策略選擇」的決策關係式。 因此，本研究認為企業在做轉型升級的決策時，千萬不要忽略企業本身的「學習能力」是否能承載「目標產業的知識特質」？建議企業宜在所欲朝向轉型升級之「目標產業的知識特質」下，考量企業本身的「學習能力」強弱，評估本身「企業轉型升級壓力」的大小，最終對「企業轉型升級策略」做出合乎自身最佳利益的理性選擇。此外，本研究亦建議企業或可藉由參考「企業學習能力系統-SOFA模型」來規劃建構或是強化自身的「企業學習能力」，以因應未來無窮的變局與挑戰！ / Abstract This research is conducted by exploration and explanation between theoretical model and case studies to prove the key role of the enterprise’s learning ability (ELA) in the procedure of the enterprise’s transformation and the option of strategy. The researcher selected cases from information technology industry which contributed most to Taiwan economic growth in recent years to explain the influence of ELA on selecting the strategy of transformation and to explore the relevance among the characteristics of objective industrial knowledge, ELA and the pressure of enterprise transformation. This thesis applied content analysis to explore the documents from two big enterprises of information hardware , trying to systematically study their learning ability and to find out how they make a decision of transformation. According to the analyses of these two cases, the study has got the following conclusions： 1.The collection of empirical indexes of enterprise learning ability (ELA). 2.The pressure of enterprise transformation will influence the option of transformation strategy. The smaller the pressure is , the bigger the chance for the enterprise choosing aggressive way to transform would be. On the contrary, the bigger the presser is , the bigger the chance for the enterprise choosing conservative way to withdraw would be. 3.The performance of ELA will influence the option of enterprise transformation strategy. The stronger the ELA is , the bigger the chance for the enterprise choosing aggressive way to transform would be. On the contrary, the weaker the ELA is , the bigger the chance for the enterprise choosing conservative way to withdraw would be. 4.The formula of enterprise learning pressure proves the existence of simple mathematical relevance among ELA, the characteristics of objective industrial knowledge and the pressure of enterprise transformation. 5.The decision-making formula of the option of enterprise transformation strategy. As a result , this research indicates that an enterprise making transformation decision should never neglect the fact whether its ELA could undertake the characteristics of objective industrial knowledge or not . This research suggests that enterprises facing transformation pressure from the characteristics of objective industrial knowledge had better take their learning ability into consideration , and finally make a rational choice of transformation strategy to meet their best needs. In addition , this research recommends that enterprises might use “Enterprise Learning Ability System (ELAS)” i.e. “SOFA model” to construct or strengthen their learning ability in order to cope with countless challenge in the future.

本研究主要透過新產品的開發專案，探討技術知識特質對組織知識創造平台的影響。研究範圍以台灣電腦網路廠商為主，針對其產品創新表現優秀的企業為主，深入訪談其產品開發專案負責人與核心成員，瞭解其產品開發的過程，與組織知識的創新平台。本研究結果顯示如下： 一、技術知識特質會影響台灣電腦網路廠商之知識創造平台 （一）技術知識路徑相依度低之產品開發專案，CEO在概念與生成及發展扮演重要角色。技術路徑相依度高的開發專案，概念的生成主要來自於各功能性部門。 （二）技術知識路徑相依度低的專案，與上游技術網路的成員保持較緊密的關係。技術知識路徑相依度高的專案，與上游技術網路成員保持較鬆散的關係。 （三）當組織開發的產品為新產品線的研究發展時，團隊管理者偏向「專案管理型」的角色，與市場方面的連結則以PM/行銷/銷售部門為主。當組織開發的產品為擴展公司現有產品線的深度時，團隊管理者偏向「總經理型」的角色。當組織開發的產品為改良或修正現有產品時，團隊管理者偏向「企劃型」的角色。 （四）當組織開發的產品為新產品線的研究發展時，組織傾向於使用「自主型團隊」來進行產品開發。當組織開發的產品為擴展公司現有產品線的深度時，組織傾向於使用「重型團隊」來進行產品開發。當組織開發的產品為改良或修正現有產品時，組織傾向於使用「輕型團隊」來進行產品開發。 （五）技術知識複雜度高，則技術網路成成員種類較多。技術知識複雜度低，則技術網路成員種類較少。 （六）技術知識複雜度愈高，組織溝通方式傾向以整合問題解決模式，若生產在專案過程參與較少，則研發與生產之間會透過產品工程做連結。 （七）技術知識複雜度高，則團隊成員組成多元程度較高。技術知識複雜度低，則團隊成員組成多元程度較低。 二、台灣電腦網路廠商知識創造平台的特性 （一）在組織知識創造的場域（Ba）中，對組織成員適度的關懷（Care）是台灣優秀電腦網路廠商的特色。 （二）在Dialoing Ba中，正式與非正式的溝通同樣為外化過程中不可或缺的方式。 （三）台灣優秀的電腦網路廠商的創新類型偏重於架構式創新，並與國外技術提供者保持適度的跨組織的知識交流。 （四）技術知識特質對組織知識創造的場域（Ba）的影響並不明顯。

在當前競爭日益激烈的網際網路商業環境中，企業對能提升經營績效之創新管理方法與工具的需求更形殷切。尤其在資訊科技快速發展的推波助瀾下，各式新型商品與新穎服務的開發與提供，不但改變了傳統的供需關係，更使企業經營面臨必須全面檢討與不斷創新的壓力。故在知識經濟時代裏，組織的經營重心將是擺在創新上，而新產品的開發又是在創新上最具體的成果，雖然研究發展活動需要投入相當多的資源，但是卻是一個科技公司所依賴維持競爭力的一項企業活動。 　　基於此，故本論文將在知識創新和研發程序二者之間做相關性探討，而所選擇的專案案例是以企業應用軟體研發程序專案為基礎，從此基礎試著以知識創新活動內容的過程中和技術知識特質中，分析出屬於企業應用軟體產業的知識創新活動內容中的行為為何?以及技術知識特質和這些知識創新行為之間關聯性，進而提供以知識創新行為基礎，架構如何發展成功的研發程序模式，來提昇企業競爭力。 　　為了分析客觀起見，所選擇的應用軟體研發程序專案案例將有三種不同個案---1.個案一「ERP導入專案」，2.個案二「企業應用客製化軟體開發專案」，3.個案三「企業協同作業方法論專案」。而這三種不同個案有其三個不同類型---導入程序、客製化軟體開發程序、作業方法論程序。這些不同類型在分析軟體技術知識特質和知識創新活動行為之間關聯性，將試著找出共同點，進而得出本論文的研究發現。 　　從整個論文發展過程中，可知最主要是要發現在企業應用軟體研發程序下的軟體技術知識特質應該運用何種知識創新行為，並以此行為做為企業應用軟體產業在研發程序專案順利完成的成功因素。 / On competitive internet business environment, corporate need innovation management methodology and tool , in order to submit business performance urgently. Especially, sorts of new product and service provide content by information technology development submit rapidly, but also change traditional supply-demand concern, not only corporate business must face to discussing impress with continual innovation totally. On knowledge economic decade, it's important to innovate that organization business aimed, and new product development is physical result in innovation. Maybe R&D activity need input more resources, it is need business R&D activity that one technology corporate maintain competitive. 　　Based on the above mentioned, The text do relate discussion between knowledge innovation and R&D procedure. Its selected case is base on business application software R&D procedure project, with knowledge innovation activity and software technical knowledge nature by these cases, analysis what is its content with knowledge innovation for corporate application software industry, and what is relation between knowledge innovation activity and software technical knowledge nature, more, it design module how to develop success R&D procedure based on knowledge innovation in order to submit corporate competition. 　　Because of analysis seriously. The text select three sorts of cases: case1: ERP implementation project; case2: business application customized development software project; case3: business collaboration process methodology project. The text try to find common item with these different cases in order to obtain research discovery by analysis relation between knowledge innovation activity and software technical knowledge nature. 　　From the text development procedure, it mainly find which knowledge innovation content on software technical knowledge nature for business application software R&D procedure, and take these content to success factory for R&D project on business application software industry.

本研究針對台灣工具機產業廠商，探索其研發專案知識管理對新產品開發績效的影響，及其技術知識特質對知識管理的關聯性。本論文以深入個案訪談法為主要的研究方法，訪談國內具代表地位的二家工具機業大廠之設計及開發部門，並自其中各選擇二個研發專案作為研究對象。 　　本研究歸納分析所得到的研究發現如下： 　　【研究發現一】研發專案知識吸收來源愈多、範圍愈廣、組織學習活動愈多，其新產品開發績效愈高。 　　【研究發現二】研發專案知識創造技術突破愈多、創新價值愈高，其新產品開發績效愈高。 　　【研究發現三】研發專案知識蓄積文件化程度愈高、蓄積活動愈多、累積專案核心能耐愈多，其新產品開發績效愈高。 　　【研究發現四】研發專案知識擴散方式愈多、擴散活動愈多，其新產品開發績效愈高。 　　【研究發現五】技術知識變動程度對研發專案的知識管理有明顯的影響。 　　【研究發現六】技術知識外顯程度對研發專案的知識管理有明顯的影響。 　　【研究發現七】技術知識路徑相依度對研發專案知識管理的影響，似乎不是很明顯。 　　【研究發現八】技術知識模組化程度對研發專案知識管理的影響，似乎不是很明顯。 　　【研究發現九】技術知識複雜化程度對研發專案的知識管理有明顯的影響。 　　因此，本研究建議企業為了提升新產品開發的成效，的確需要強化知識管理，同時其研發部門應設計符合技術知識特質及利於推動知識管理的組織型態與作為。平時應作好內部技術傳承及外部技術來源佈置工作，並在新產品開發不同階段妥善配置適合的資源與人力。 / This research is focused on Taiwan's CNC machine industries for exploring the impacts of knowledge management on the performance of new product development. The influence of the characteristics of technological knowledge on knowledge management is also studied. The research was conducted mainly based on deep case studied. The research subjects include four R&D projects two which are selected from two companies of CNC machine industry. 　　The preliminary conclusions are as follows: 　　1. The more the R&D project knowledge is absorbed from different sources, wide ranges,and multiple organizational learning activities, the better the performance of new product development would be. 　　2. The more the R&D project knowledge creates the technological breakthrough and thenewly added value, the better the performance of new product development would be. 　　3. The more the R&D project knowledge is accumulated with the documentation, the amass of activities, and the core resourcefulness, the better the performance of new product development would be. 　　4. The more the R&D project knowledge is diffused in different patterns and activities, the better the performance of new product development would be. 　　5. There exists a direct relationship between the knowledge management of R&D project and the degree of change of technological knowledge. 　　6. There exists a direct relationship between the knowledge management of R&D project and the degree of explicitness of technological knowledge. 　　7. There doesn't exist a direct relationship between the knowledge management of R&D project and the degree of path dependence of technological knowledge path. 　　8. There doesn't exist a direct relationship between the knowledge management of R&D project and the degree of modualization of technological knowledge. 　　9. There exists a direct relationship between the knowledge management of R&D projects and the degree of complexity of technological knowledge. 　　As a result, it is suggested that the R & D departments of the companies possessed with different characteristics of technological knowledge should design the organizational form and activities that are conformed to the characteristics of technological knowledge for facilitating the practices of knowledge management. 　　The internal technology inheritance and the external technology resource deployment have to be executed ordinarily; and the appropriate resources as well as human powershall be properly allocated in accordance with the different steps of new product development with a view to intensifying the satisfactory result.

本文探討景氣因素、研發外溢效果及技術知識特質對IC設計業研發支出遞延效應之影響。本研究主要採用Lev and Sougiannis (1996)所發展之研發支出遞延效應實證模型，以國內IC設計業上市櫃公司為對象，透過分析產業特性，區分為多應用性IC設計群組及單應用性IC之資訊、通訊及消費性群組，並探討其研發支出遞延效應。研究發現如下： 一、在研發支出遞延效應中，IC設計業受景氣之影響僅限於當期之研發支出；就研發支出效益受影響程度上，IC設計業亦低於其他IC產業。此結果顯示，IC設計業由於具備產品多元化和應用多元等利基市場特性，且在國內是屬於成長型產業，故景氣影響程度不如其他下游產業來的大。 二、多應用性IC設計公司之研發支出所創造之未來效益，比單應用性IC設計公司高。多應用性IC設計公司因為受到研發外溢效果之影響，其當期及遞延一期之研發支出，會比單應用性IC設計公司創造更高之效益。此結果顯示，多應用性IC設計公司投入於不同領域產品之研發支出，存在類似產業內外溢效果，因此亦加強研發支出對未來效益貢獻之程度。 三、資訊類單應用性IC設計公司之研發支出，對未來所創造之效益金額及持續年限，均未優於通訊類及消費類單應用性IC公司。本研究發現，技術路徑相依度及技術變動程度兩種技術知識特質，並不能完全解釋單應用性不同群組之研發支出所創造未來效益的程度，而必須同時考量下游應用市場之目前狀況及未來潛力，才能對其研發支出遞延效應做出更正確之推論。 / This thesis analyzes three R&D performance issues of the IC design firms in Taiwan. First, it addresses the effect of the fluctuating economic cycle in the semiconductor sector on the R&D performance of design and non-design firms in the IC industry. Secondly, this study examines the R&D spillover effect on the R&D performance of the multifunctional and single-functional groups of IC design firms. Finally, this study discusses how technological knowledge (path independence and complexity) influences the R&D performance of the three subgroups (computer, communication, and consumer) of single-functional IC design firms. Three major findings of the study are as follows: 1.The fluctuating economic cycle in the semiconductor sector has less influence on the R&D performance of the IC design firms than that of the IC non-design firms. The fluctuation affects the R&D expenditure of IC design firms only in the current year, but that effect on the IC non-design firms exist in the current year and also the following year. The R&D performance of IC design firms is also less influenced. 2.The multifunctional IC design firms generate more benefit from R&D expenditure than single-functional ones, suggesting that the former group has a stronger R&D spillover effect. 3.Although the computer subgroup of IC design firms possesses high technological path dependence and low technological complexity, its R&D performance is not better than the other subgroups. This finding suggests that technological path dependence and complexity do not fully explain the difference in R&D performance among the three subgroups of single-functional IC design firms.