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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
81

Biochemische, molekularbiologische und genetische Untersuchungen über strukturelle Voraussetzungen für DNA U-Endonukleaseaktivität in der ExoIII-Familie von DNA Reparaturenzymen / Biochemical, molecular biological and genetic studies on structural requirements for DNA U-Endonuclease activity in the ExoIII family of DNA repair enzymes

Ber, Svetlana 19 January 2010 (has links)
No description available.
82

Investigations into the mode of action of the DNA uridine endonuclease Mth212 of Methanothermobacter thermautotrophicus ΔH / Untersuchungen über die Wirkungsweise der DNA-Uridin Endonuklease Mth212 aus Methanothermobacter thermautotrophicus ΔH

Ciirdaeva, Elena 22 January 2010 (has links)
No description available.
83

Effekte von Hypericin auf humane renale Karzinomzellen in vitro / Effects of hypericin on human renal carcinoma cells in vitro

Busse, Ann-Christin 22 January 2010 (has links)
No description available.
84

Untersuchungen zur Wirksamkeit von Dacarbazin und Temozolomid bei der Behandlung des kutanen Melanoms in Assoziation mit DNA-Reparatur / Assessment of the Efficacy of Dacarbazine and Temozolomide in Melanoma Treatment in Association with DNA-Repair

Böckmann, Lars 15 January 2010 (has links)
No description available.
85

Untersuchungen zum Einfluss von 211At, 188Re und Doxorubicin auf die DNA-Schädigung humaner Lymphozyten

Runge, Roswitha 06 October 2009 (has links)
Ionisierende Strahlung verursacht in Abhängigkeit von den strahlenphysikalischen Eigenschaften der Radionuklide Zellschäden unterschiedlicher Komplexität. An humanen Lymphozyten wurde untersucht, ob die biologische Wirksamkeit von Alpha- und Betastrahlung sowie der Einfluss von Doxorubicin der Qualität des Strahlenschadens zugewiesen werden kann. Die DNA-Schäden und deren Reparatur wurden mit zellbiologischen Methoden quantifiziert.
86

Greener, cheaper, or more sustainable: reviewing sustainability assessments of maintenance strategies of concrete structures

Scope, Christoph, Vogel, Maria, Guenther, Edeltraud 22 December 2021 (has links)
Concrete is the most widely used material in construction and infrastructure, and is often reinforced by steel to improve tensile strength. Despite its enduring popularity, the material’s inherent weaknesses – namely corrosion damage and material fatigue – combined with ageing infrastructure, poses a challenge to both decision-makers and civil engineers to optimise sustainable infrastructure services. This article explores and synthesises the sustainable potential of maintenance and repair methods using concrete and cement-based composite materials. We draw on published case studies where sustainability assessments have been applied within this field. We also included cases that describe themselves as a type of sustainability assessment, but lack the assessment of all dimensions. Our research aims, firstly, to identify what maintenance interventions were assessed by means of sustainability criteria. Second, it explores the basic conceptual understanding which underlies each sustainability assessment. Third, it analyses the many methodological choices made for system boundaries, selection of indicators, or forms of aggregation. We have applied a systematic literature review to develop evidence-based management knowledge; this shows that current sustainability assessments are diverse regarding system boundaries, their scope, levels of detail, and overall quality. Although there is a trend towards more holistic types of assessment, environmental and economic sustainability dominated our sample, with global warming and energy consumed being most often reported. External costs, if included in the assessment, drive the overall economic score, while life cycle sustainability assessment is applied to only three cases. The most critical and challenging issues were shown to be the long-term orientation of maintenance measures and the complexity of undertaking a truly holistic sustainability assessment. To that end, we have stimulated scholarly discussion on further methodological progress to align with the good practices identified in our review, and call for greater application of these methods in the construction industry.
87

Untersuchungen zur Funktion der Gene MPH1 und MMS2 aus Saccharomyces cerevisiae bei der fehlerfreien Umgehung von replikationsarretierenden DNA-Schäden / Studies on functions of the genes MPH1 and MMS2 from Saccharomyces cerevisiae during error free bypass of replication blocking DNA-lesions

Ede, Christopher 13 January 2010 (has links)
No description available.
88

Structural characterization of the lysosomal 66.3 kDa protein and of the DNA repair enzyme Mth0212 by means of X-ray crystallography / Strukturelle Charakterisierung des lysosomalen 66.3 kDa Proteins und des DNA-Reparaturenzyms Mth0212 mittels Röntgenkristallographie

Lakomek, Kristina 28 April 2009 (has links)
No description available.
89

Zur Funktion des MPH1-Gens von Saccharomyces cerevisiae bei der rekombinativen Umgehung von replikationsarretierenden DNA-Schäden / On the function of the MPH1 gene from Saccharomyces cerevisiae in recombinational bypass of replication arresting DNA lesions

Schürer, Anke 22 January 2004 (has links)
No description available.
90

Xeroderma-Pigmentosum-Gruppe-C- und -G-Gen-Polymorphismen: Alternatives Splicing und funktionelle DNA-Reparatur beim multiplen Melanom / Xeroderma-Pigmentosum-group-C and -g-gene-polymorphisms: alternative splicing and functional DNA-repair in multiple melanoma patients

Vollert, Seike 23 May 2011 (has links)
No description available.

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