Cardiovascular diseases are the leading cause of death in most industrialised countries and in developing countries the trend in cardiovascular-related deaths is increasing. World-wide, type 2 diabetes mellitus (T2DM) is an emerging cause of disability and premature death. Both these conditions are closely associated with the consumption of energy-dense foods and food products that are poor in nutrients, as well as with a sedentary lifestyle. Pharmacological and surgical interventions can improve the outcome and delay the progression of the disease, but in terms of population-level prevention there is no substitute for the adoption of a healthy lifestyle. SETTING The underlying studies were conducted in Västerbotten (the VIP study), and in Norrbotten and Västerbotten combined (the MONICA Project). Norrbotten andVästerbotten are the two northernmost counties in Sweden. Since the mid-1980sthe prevalence of cardiovascular disease has decreased and diabetes rates haveremained stable in this region, despite of an unbroken trend of increasing body weight. OBJECTIVE The aim of this thesis is to describe changes in reported dietary habits, estimatetheir relative importance as risk factors for diabetes and cardiovascular disease, and finally to identify lifestyle components as potential targets for intervention. RESULTS The first paper describes changes in self-reported food consumption between 1986 and 1999. During this period, the population in question switched from products with high saturated fatty acid content (e.g. milk containing 3% fat, butter) to foods containing less saturated fat (e.g. milk containing 1.5% fat, vegetable oil, low-fat margarine); pasta and rice were consumed more often, and potatoes were consumed less. Convenience foods (e.g. hamburgers, snacks, sweets) became more popular, whilst traditional dishes (e.g. potato dumplings, black pudding, blöta) decreased in popularity. Fruit and vegetable intake remained low. In paper two we study the effects of these changes in food intake on the risk of developing T2DM using body fat distribution as an early indicator. Increased consumption of convenience foods was associated with unfavourable changes (smaller hip circumference and larger waist circumference), whereas the increased consumption of vegetable oil and pasta was associated with low-risk fat distribution. In the third paper we report studies on the association between fat consumption and T2DM. We used the pattern of fatty acids in the membranes of red blood cells as a marker of fat intake. In addition to confirming earlier findings (markers of the intake of saturated fat are associated with increased risk of T2DM and markers of unsaturated fat are associated with reduced T2DM risk), we also identified associations between two markers of milk-derived saturated fat intake and enterolactone, a biomarker of dietary fibre intake, and the risk of developing myocardial infarction. Our results indicate that moderately high levels of enterolactone intake in men are associated with lower risk of experiencing myocardial infarction. Manuscript 5 ranks education level, physical activity, smoking status, and self-reported intake of dietary fibre and fatty acids according to their effects on body fat distribution. Increased levels of physical activity, a higher education level and a reduced intake of saturated fat from meat were ranked as the most strongly associated factors in both men and women. Increased intake of dietary fibre from grains in women, and increased intake of dietary fibre from fruits and vegetables in men, was also inversely associated with average waist circumference. CONCLUSION Both questionnaire-based and biological markers of the risk of developing diabetes or cardiovascular disease have been identified. Based on available population level measurements, reduced consumption of convenience foods, increased consumption of whole-grain products, fruits and vegetables, vegetable oil and pasta as well as increased physical activity are potential goals for interventions in northern Sweden.

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The objectives of the study were (1) to quantify adherence rate among the study participants in the ART unit and (2) to identify factors that contribute to non-adherence. This cross sectional study was carried out at Nekemete referral clinic. Data was collected using a self-developed structured questionnaire where a total of 338 participants grouped into adherent and non-adherent based on a score derived from an adherence assessment were interviewed. Data was analysed using the Statistical Package for Social Sciences (SPSS) version 17.0. By using multivariate analysis of variables identified as correlates of adherence, non-adherence was common among those; with age between 18-30 yrs, with no education, who were not married, who had no pipe water supply, those with no electricity in the house, who perceived had no access to assistance from providers, who perceived the health care providers (HCPs) did not keep information confidentially, who had a language barrier with providers, and who were treated with a psychiatric illness. The study concludes that adherence is multi-factorial and varies significantly by individual and care setting. Psychosocial factors were found to impact adherence and should be analysed in more detail by further studies. Three psychosocial factors were independently associated with poor adherence: the study found that patients perceiving poor access; those perceiving problems in information confidentiality (and possibly experiencing stigmatisation); and having psychiatric morbidity (and possibly with less social support) are more likely to be non-adherent. Furthermore, individuals without electricity and those without piped water supply, implying low income, are at risk for non-adherence / Health Studies / M.A. (Public Health)

Made available in DSpace on 2011-05-04T12:42:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2009 / Introdução: A resiliência pode ser conceituada como um processo dinâmico que leva à adaptação positiva diante de uma adversidade e que envolve a interação entre processos sociais e intrapsíquicos de risco e de proteção. Metodologia: Tese composta por trêsartigos independentes, que apresentam a resiliência como aspecto comum. O primeiro deles apresenta uma revisão sistemática sobre a operacionalização do conceito de resiliência em estudos epidemiológicos sobre o transtorno de estresse pós-traumático (TEPT) seguido a eventos de violência urbana e/ou íntima. O segundo artigo traz uma revisão sistemática sobre as propriedades psicométricas da Escala de Resiliência e de suas diferentes versões. As bases de dados nas duas revisões foram: ISI; MEDLINE; PILOTS e LILACS. O terceiro artigo investigou os fatores associados à resiliência a eventos traumáticos a partir dos dados de um inquérito epidemiológico domiciliar conduzido com uma amostra representativa da população com 15 anos ou mais residente na cidade de São Paulo. A associação foi investigada através de modelos logísticos multivariados hierárquicos, tanto para traumas intensos quanto para aquelesleves/moderados. Resultados: Artigo 1) Estudos epidemiológicos sobre violência íntima e/ou urbana são relativamente recentes e muito heterogêneos no modo como operacionalizam o conceito de resiliência junto ao TEPT. Artigo 2) A literatura apresenta críticas sobre a capacidade de um instrumento único abranger a complexidade do fenômeno de resiliência. No entanto, a Escala de Resiliência vem sendo amplamente aplicada, apresentando boas propriedades psicométricas em suas diferentes versões, e sugerindo ser um instrumento útil para aferir alguns fatores individuais de resiliência. Artigo 3) O estudo seccional conduzido em São Paulo exemplificou a proposta de um método de análise que combina algumas formas de operacionalização da resiliência, demonstrando congruência dos achados (isto é, com maiores escores da Escala de Resiliência predizendo ausência de patologia após um evento traumático e com o grupo classificado como resiliente - através dessa operacionalização de adaptação positiva - apresentando os maiores escores de bem-estar). Conclusão: Apesar da complexidade do fenômeno de resiliência, a congruência dos achados aponta para a possibilidade de uma cada vez melhor apreensão do construto, favorecendo o entendimento sobre o que pode contribuir para a superação de eventos traumáticos pelos indivíduos a eles expostos. / Introduction: The resilience can be conceptualized as a dynamic process that leads to positive adaptation in the face of adversity and involves the interaction between intrapsychic and social processes of risk and protection. Methods: Thesis of three independent articles, which have the resilience as common theme. The first one presents a systematic review on the operationalization of the resilience concept in epidemiological studies on Postttraumatic Stress Disorder (PTSD) following events of urban and/or intimate violence. The second article provides a systematic review on the psychometric properties of the Resilience Scale, and their different versions. The databases in the two revisions were: ISI, MEDLINE, LILACS and PILOTS. The third article investigates the factors associated with resilience to traumatic events from the data of a household survey conducted with a representative sample of the population aged 15 years or more living in the city of São Paulo. The association was investigated using hierarchical multivariate logistic models for both trauma intense as those for light / moderate. Results: Article 1) Epidemiological studies on PTSD followed intimate and/or urban violence are relatively recent and very heterogeneous in how operationalize the resilience concept. 2) The literature presents criticism on the ability of a single instrument to cover the complexity of the resilience phenomenon. However, the Resilience Scale has been widely applied, showing good psychometric properties in different versions, and suggesting to be a useful tool to assess individual factors of resilience. 3) The cross-sectional study conducted in São Paulo illustrated the proposal for a method of analysis that combines some forms of operationalization of resilience, demonstrating consistency of findings (with higher scores of the Resilience Scale predicting absence of disease after a traumatic event and the group classified as resilient - through the operationalization of "positive adjustment" - showing the higher scores of well-being). Conclusion: Despite the complexity of the phenomenon of resilience, the congruence of findings points to the possibility of an even better understanding of the construct, facilitating the comprehension of what can help to overcome traumatic events on individuals exposed to them.

Contexte: L’arthrite juvénile idiopathique (AJI) est l’une des maladies chroniques auto-immune les plus répandues chez les enfants et est caractérisée par des enflures articulaires (maladie active), de la douleur, de la fatigue et des raideurs matinales pouvant restreindre leur niveau de participation aux activités quotidiennes (par exemple: les loisirs, l’activité physique, la mobilité et les soins personnels) à la maison comme à l’école. Participer aux activités de loisirs et à l’activité physique a des bienfaits au niveau de la santé et du développement de tous les enfants et démontrent aussi des effets positifs qui réduisent les symptômes des maladies chroniques telle l’AJI. Malgré ces bienfaits la participation aux loisirs chez les jeunes avec l’AJI demeure largement sous-étudiée. Objectifs: Cette étude vise à évaluer le niveau de participation aux loisirs et à l’activité physique chez les enfants et les adolescents atteints d’AJI, ainsi qu’à identifier les facteurs liés à la maladie, la personne et l’environnement. Méthodes : L’évaluation du niveau de participation et l’exploration des facteurs associés aux loisirs et à l’activité physique ont été complétés par l’entremise d’une revue systématique de la littérature, l’analyse de données d’un échantillon national représentatif d’enfants canadiens atteints d’arthrite âgés entre 5 et 14 ans (npondéré = 4350), ainsi que l’analyse standardisée du niveau de participation aux loisirs à l’aide du Children’s Assessment of Participation and Enjoyment (n=107) et la mesure objective de l’activité physique par accéléromètre (n=76) auprès d’un échantillon d’enfants (âgés entre 8 et 11 ans ) et d’adolescents (âgés entre 12 et 17 ans) suivis en clinique de rhumatologie à l’hôpital de Montréal pour enfants, Centre Universitaire de Santé McGill. Les résultats cliniques ont été comparés à des données normatives, ainsi qu’à un groupe contrôle sans AJI. Nous avons exploré les facteurs associés avec le niveau de participation aux loisirs et à l’activité physique en utilisant les modèles de régression linéaire multiple et l’analyse hiérarchique. Résultats : Les enfants et les adolescents atteints d’AJI participent à une multitude d’activités de loisirs; cependant ils sont moins souvent impliqués dans des activités physiques et de raffinement en comparaison aux autres types d’activités de loisirs. Ceux avec l’AJI étaient en général moins actifs que leurs pairs sans arthrite et la plupart n’atteignaient pas les recommandations nationales d’activité physique. Les garçons avec l’AJI participent plus souvent à des activités physiques et moins aux activités sociales, de raffinement et de développement de soi en comparaison avec les filles ayant l’AJI. En général, être un garçon, être plus âgé, avoir une meilleure motivation pour participer aux activités de motricité globale, avoir un statut socio-économique plus élevé et être d’origine culturelle canadienne sont associés à un niveau de participation plus élevé aux activités physiques. La préférence pour les activités de raffinement, un niveau d’éducation maternelle plus élevé et être une fille étaient associés à un niveau de participation plus élevé aux activités de raffinement. Conclusion: La participation aux loisirs et à l’activité physique en AJI est un concept complexe et semble surtout être expliqué par des facteurs personnels et environnementaux. L’identification des facteurs associés aux loisirs et à l’activité physique est très importante en AJI puisqu’elle peut permettre aux professionnels de la santé de développer des interventions significatives basées sur les activités préférées des enfants, améliorer l’observance au traitement et promouvoir des habitudes de vie saine. / Background: Juvenile idiopathic arthritis (JIA), one of the most common chronic childhood autoimmune diseases, is a heterogeneous inflammatory condition characterised by joint inflammation (i.e. active disease), chronic pain, fatigue and morning stiffness, which may interfere with age-appropriate daily activities (i.e. leisure and physical activity, mobility and self-care), both at home and at school. Involvement in leisure and physical activity is beneficial to the health and development of all children and adolescents, and has also shown to help mitigate the effects of disease among those with chronic conditions such as JIA. Despite the benefits of leisure participation this subject remains vastly understudied in JIA. Objective: The aim of this thesis was to assess participation in leisure and physical activity among children and adolescents with JIA, as well as identify associated disease-related, personal and environmental factors. Methods: The assessment of patterns and exploration of potential predictors of participation in leisure and physical activity in children and adolescents with JIA was completed through a systematic review of the literature, analysis of survey data from a nationally representative sample of Canadian children with arthritis (age range = 5 to 14 years, nweighted = 4350), as well as the standardized assessment of leisure with the Children’s Assessment of Participation and Enjoyment (n=107) and the objective measurement of physical activity with accelerometer (n=76) among a clinical sample of children (age range = 8 to 11 years) and adolescents (age range = 12 to 17 years) with JIA followed at the Rheumatology clinic at the Montreal Children’s Hospital, McGill University Health Center. Clinical data were also compared to normative data and children and adolescents without JIA. We explored factors associated with participation in leisure and physical activity using multiple linear regression models and hierarchical analysis. Results: Children and adolescents with JIA participated in an array of leisure activities; however involvement was least frequent in active physical and skill-based leisure activities compared to other types of activity. Those with JIA were generally less physically active than healthy peers without JIA, and most with JIA did not meet national recommendations for physical activity. Boys with JIA were more likely to engage in physical activities, and less likely to take part in social, skill-based and self-improvement activities than girls with JIA. In general, being a boy, older age, greater mastery motivation for gross motor skills, higher socio-economic status and being of Canadian cultural background were associated with increased participation in more physical activities. Preference for skill-based activities, higher maternal education and being a girl were associated with increased participation in skill-based activities. Conclusion: Participation in leisure and physical activity in JIA is a complex concept and is mostly explained by personal and environmental factors. The identification of factors associated with leisure participation and physical activity is of utmost importance in JIA as it may aid health care professionals to tailor meaningful intervention plans based on preferred activities, improve adherence to treatment and help promote healthier lifestyles.

This study aimed to provide evidence on knowledge of attitudes toward standard precautions (SPs) and its practice of Healthcare Workers (HCWs) in government and private hospitals in Botswana. It utilised descriptive cross-sectional methodology. A range of significant findings were revealed. Good practice of SPs was noted more amongst the HCWs in government than in private hospitals. Knowledge of SPs amongst HCWs in government hospital was significantly and positively correlated to good practice of SPs. Registered Nurses (RNs) had better knowledge of SPs than HealthcareAssistants (HCAs).There was no significant difference between RNs and HCAs practice of SPS and attitudes toward the same. No significant difference in the knowledge, attitudes and practice of SPs was noted between General Practitioners (GPs) and RNs. No significant difference in the knowledge, attitudes and practice of SPs was observed between GPs and HCAs. The study findings have implications for the application of SPs in practice / Health Studies / M.A. (Public Health)

Bakgrund: Tonårsperioden är en avgörande tid för unga. Ungdomars utsatthet för våld utgör en väsentlig folkhälsofråga globalt och nationellt. Vid mötet med ungdomar kan barnmorskor på ungdomsmottagningar ta upp ämnen som relationer, livsstil och sexuellt beteende. Västra Götalandsregionen har utvecklat SEXIT, en metod som kan bidra till att identifiera ungdomars sexuella risker och våldsutsatthet.   Motiv: Ungdomars sexuella och reproduktiva hälsa och rättigheter behöver förbättras. Genom att kartlägga ungdomars självrapporterade sexuella beteende och erfarenheter av våldsutsatthet kan en bättre uppfattning om vilka risker som de utsätter sig eller andra för nås.    Syfte: Att via SEXIT kartlägga ungdomars sexuella beteende och deras utsatthet för våld samt att utforska eventuella skillnader mellan ålder och kön.   Metod: Stickprovsundersökning med 284 ungdomar vid en ungdomsmottagning i Norrland under 2022, som besvarat SEXIT enkäten som innehöll bakgrundsfrågor, våldsutsatthet och sexuella riskbeteenden. 96 sorterades bort, 188 deskriptiva statistiska analyser utfördes i statistikprogrammet Jamovi 2.4.8.0., med uppdelning i ungdomar och unga vuxna samt jämförelser mellan våldsutsatthet, sexuellt risktagande, ålder och kön.   Resultat: En hög andel ungdomar och unga vuxna rapporterade utsatthet för fysiskt, psykiskt och sexuellt våld. Fler kvinnor uppger att de blev pressade till sex (kvinnor 22%, män 3%). Mer än en tredjedel (34%) av kvinnor rapporterade utsatthet för psykiskt våld och motsvarande siffra för män är 38%. Unga vuxna män angav att de oftare har blivit utsatt för fysiskt våld jämfört med unga vuxna kvinnor (p=0.018). Mer än hälften av kvinnor (60%), rapporterade att de hade utsatts för oönskade handlingar mot sin vilja. 15% använde sex som en strategi för att hantera känslomässiga svårigheter eller en form av självskada.  Konklusion: En betydande andel ungdomar rapporterade att de utsatts för psykiskt, fysiskt och sexuellt våld, och de tar stora sexuella risker. Tillgängliga ungdomsmottagningar är väsentligt för deras hälsa. / Background: Adolescence is a crucial period for youth. Youth exposure to violence is a public health issue globally and nationally. Midwives at youth clinics adress topics such as relationships, lifestyle and sexual behaviour. Västra Götaland Region has developed SEXIT, method to identify youth’s sexual risks and experiences of violence.  Motive: Adolescents' sexual and reproductive health needs to be improved and their rights strengthened. By mapping young people's sexual behavior and experiences of violence, we can see what risks they expose themselves to or expose others to.  Aim: to map adolescens´ sexual behavior and their exposure to violence through SEXIT and to explore potential differenses between age and gender.  Method: Survey with 284 youths at a youth clinic in Norrland during 2022, responding to the SEXIT questionnaire containing background questions,exposure to violence, and sexual risk behaviors. 96 were excluded, and 188 analyses were conducted using the statsistical software Jamovi 2.4.8.0, categorized by youths and young adults, including comparisions between exposure to violence, sexual risk-taking, age and gender.   Results: A high proportion of adolescents and young adults reported exposure to physical, psychological and sexual violence. More women state that they are pressured into sex (women 22%, men 3%). Over a third(34%) of women report exposure to psychological violence, corresponting to men who report 38%. Young adult men indicated that they have often been exposed to physical violence compared to young adult women (p=0.018)  More than half of women reported experiencing unwanted actions against their will. 15% used sex as a strategy to cope with emotional difficulties or as a form of self-harm.   Conclusion: A significant proportion of youths report exposure to psychological, physical and sexual violence, and they take substantial sexual risks. Accessible youth clinics are crucial for their health.

Contexte : Les interventions de promotion de la santé (IPS) en milieu scolaire visent à soutenir le développement des jeunes et promouvoir l'adoption de modes de vie sains. Une culture scolaire promotrice de santé a été identifiée comme un facteur facilitant l’adoption, la mise en œuvre et l’efficacité des interventions. Toutefois, la culture scolaire peut varier d'une école à l'autre, particulièrement dans celles accueillant des élèves issus de milieux défavorisés, et des inégalités dans l’offre d’IPS risqueraient d’exacerber les inégalités de santé existantes. Un écart de connaissances persiste sur les inégalités sociales dans la culture scolaire et l’offre d’IPS dans les écoles desservant des élèves de statut socio-économique différent. Objectifs : L'objectif était d'étudier les associations entre le niveau de défavorisation de l’école, la culture scolaire et la disponibilité d’IPS. Nous avons cherché à: (1) quantifier l'association entre la défavorisation de l’école, l'importance de problématiques de santé et la disponibilité d’IPS; (2) quantifier l'association entre la défavorisation de l’école et la culture scolaire promotrice de santé. Les résultats de l'objectif 1 ayant montré un gradient social dans la disponibilité d’IPS en matière de santé mentale, nous avons approfondi pour: (3) quantifier l'association entre des variables du contexte scolaire et la présence d’IPS de santé mentale; (4) les caractériser par rapport aux meilleures pratiques (ex. approche globale, optimisation de la culture scolaire). Méthodes : Les données sont tirées de PromeSS, une étude transversale comprenant 171 écoles primaires du Québec, Canada (2017-2019). Quatre mesures d'une culture scolaire promotrice de santé ont été développées à partir du modèle théorique «Health Promoting Schools». Des modèles de régression logistique, ANOVA unidirectionnelle et tests de Tukey ont servi à estimer les associations entre les variables d’intérêt. Des données approfondies sur un échantillon de 25 IPS de santé mentale ont été analysées dans le cadre d'une analyse de cas croisés. Résultats : Les écoles défavorisées ont signalé plus de problématiques de santé que les écoles favorisées. Les proportions d’IPS disponibles étaient similaires, sauf pour les IPS de santé mentale offertes en plus grande proportion dans les écoles favorisées. Les écoles favorisées avaient une culture scolaire plus promotrice de la santé que les écoles défavorisées, principalement en termes d'engagement avec les familles et la communauté. Les écoles plus susceptibles de mettre en œuvre des IPS de santé mentale étaient les écoles favorisées, ayant une culture scolaire plus promotrice de santé et où les problématiques de santé mentale étaient considérées comme importantes. Bien que généralement bien adaptées à leur contexte, peu d’IPS de santé mentale étaient alignées avec les meilleures pratiques. Conclusions : Cette thèse illustre l’importance du contexte dans lequel les IPS sont mis en œuvre, incluant la culture scolaire comme caractéristique essentielle pour des IPS efficaces et les conditions socioéconomiques des élèves. La capacité des écoles à établir une culture scolaire promotrice de santé et à mettre en œuvre des interventions fondées sur les données probantes devrait être renforcée, en particulier pour les écoles défavorisées, afin d'améliorer la santé des élèves et de réduire les inégalités. / Background: School-based health-promoting interventions (HPIs) are key components of public health strategies that aim to support youth development and promote the adoption of healthy lifestyles. A health-promoting school culture, which represents the school’s context for HPI implementation, has been identified as a facilitator of HPI adoption, implementation, and effectiveness. However, school culture may vary across schools and in particular, schools serving students from disadvantaged backgrounds which face known challenges for HPI implementation. Inequalities in school culture and HPI programming may exacerbate existing health inequalities across disadvantaged versus advantaged settings. Yet little is known about social inequalities in school culture or HPI availability across schools serving student populations of varying socio- economic status. Objectives: The aim of this dissertation was to investigate the associations among school deprivation, school culture and HPI availability. Specifically we aimed: (1) to quantify the association between school deprivation and each of perceived importance of health issues and HPI availability; (2) to quantify the association between school deprivation and health-promoting school culture. Because results from objective 1 showed a social gradient in the availability of mental health HPIs, we delved deeper: (3) to quantify the association between school context variables and the availability of mental health HPIs; and (4) to characterize them according to their alignment with best practices for effective school-based mental health promotion. Methods: Data were drawn from the PromeSS study, a cross-sectional survey of school principals including 171 elementary schools across Québec, Canada (2017-2019). Four measures of a health- promoting school culture were developed drawing from the Health Promoting Schools theoretical model. Logistic regression models, one-way ANOVA and post-hoc Tukey tests were used to estimate associations between school deprivation, health-promoting school culture, importance of health issues, and HPI availability. In-depth data on a sample of 25 mental health HPIs implemented in study schools were analyzed in cross-case analysis. Results: The three articles that comprise this thesis show that: (1) disadvantaged schools reported more health issues as important than advantaged schools, but similar proportions of HPIs, except for mental health HPIs (a higher proportion of advantaged schools reported offering one in the past year); (2) advantaged schools had a more health-promoting school culture than disadvantaged schools, primarily in terms of engagement with families and the wider school community; (3) in the case of mental health promotion, advantaged schools, schools with a more health-promoting school culture, and schools where mental health issues were seen as important were more likely to implement mental health HPIs; and (4) although schools generally implemented interventions that were highly tailored to their context, few mental health HPIs were aligned with best practices for effective mental health promotion (e.g., whole-school approach, optimization of school culture). Conclusion: This thesis suggests that the context in which school-based HPIs are implemented matters, including student socioeconomic conditions. It strengthens empirical support for health- promoting school culture as a crucial feature for effective HPIs. School capacity for establishing a health-promoting school culture and implementing evidence-based interventions should be reinforced, especially for disadvantaged schools to improve student health and reduce inequalities.estimate associations between school deprivation, health-promoting school culture, importance of health issues, and HPI availability. In-depth data on a sample of 25 mental health HPIs implemented in study schools were analyzed in cross-case analysis. Results: The three articles that comprise this thesis show that: (1) disadvantaged schools reported more health issues as important than advantaged schools, but similar proportions of HPIs, except for mental health HPIs (a higher proportion of advantaged schools reported offering one in the past year); (2) advantaged schools had a more health-promoting school culture than disadvantaged schools, primarily in terms of engagement with families and the wider school community; (3) in the case of mental health promotion, advantaged schools, schools with a more health-promoting school culture, and schools where mental health issues were seen as important were more likely to implement mental health HPIs; and (4) although schools generally implemented interventions that were highly tailored to their context, few mental health HPIs were aligned with best practices for effective mental health promotion (e.g., whole-school approach, optimization of school culture). Conclusion: This thesis suggests that the context in which school-based HPIs are implemented matters, including student socioeconomic conditions. It strengthens empirical support for health- promoting school culture as a crucial feature for effective HPIs. School capacity for establishing a health-promoting school culture and implementing evidence-based interventions should be reinforced, especially for disadvantaged schools to improve student health and reduce inequalities.

Externe Repräsentationen sind für das Verständnis und die Vermittlung chemischer Phänomene und Konzepte essenziell. Lernende werden mit einer Vielzahl an Darstellungen konfrontiert, mit denen sie geeignet umgehen müssen, um die darin transportierten Inhalte zu erfassen. Eine wichtige Voraussetzung für die flexible Verwendung mehrerer Repräsentationen im Lehr- und Lernprozess stellt die sogenannte Translationsfähigkeit dar, welche das Überführen verschiedener Darstellungsformen ineinander beschreibt. Empirische Studien weisen dahingehend auf Defizite bei Lernenden hin. Demzufolge untersucht die vorliegende Arbeit in einer quantitativen Querschnittstudie, inwiefern (a) Übersetzungswege und (b) zu übersetzende Stoffklassen die Übersetzungsschwierigkeit beeinflussen und (c) welche Zusammenhänge zwischen personenbezogenen Eigenschaften und der Translationsfähigkeit bei Lernenden bestehen. Die Stichprobe umfasst Lernende der 10. und 11. Jahrgangsstufe des Bundeslandes Berlin. Für die Erfassung der Translationsfähigkeit wurde ein Erhebungsinstrument konzipiert, dessen Aufgaben in einem Think-Aloud-Setting (N = 10) und in einer quantitativen Vorstudie (N = 225) pilotiert wurden. Die Auswertung der Daten erfolgte unter Anwendung von Item-Response-Theorie sowie Zusammenhangsanalysen. Die Ergebnisse (N = 629) zeigen, dass sich Übersetzungswege zwischen Moleküldarstellungen geringfügig in der Übersetzungsschwierigkeit unterscheiden und ähnlich hohe Anforderungen an die Translationsfähigkeit stellen (a). Zu übersetzende Stoffklassen zeigen Unterschiede in den Übersetzungsschwierigkeiten und damit in den Translationsanforderungen an Lernende (b). In einer multiplen Regression konnten personenbezogene Eigenschaften wie deklaratives Fachwissen und Mental Load als Prädiktoren der Translationsfähigkeit identifiziert werden (c). Die Befunde bieten damit Ansatzpunkte zum Umgang mit Lerngelegenheiten mit Translationsanforderungen und Möglichkeiten für Anschlussforschung. / External representations are important to understand and teach chemical phenomena and concepts. Students are faced with a multitude of representations, which they have to deal with appropriately to comprehend the content conveyed to them. An important prerequisite for the flexible use of several representations in teaching and learning processes is the so-called translation ability, which includes switching from one form of representation to another. However, empirical work reveals deficits among students. To shed light on these deficits, this work uses a quantitative cross-sectional study to investigate how the variables (a) translation path and (b) chemical class influence the translation difficulty, and (c) which correlations exist between students’ personal characteristics and their translation ability. The sample consists of 10th and 11th grade students from high schools in Berlin. To assess translation ability, a multiple-choice test was developed and validated in a think-aloud setting (N = 10) and a quantitative pre-study (N = 225). The data were analyzed using item response theory, as well as correlation and regression analyses. The results (N = 629) indicated that translation paths between molecular representations differ only slightly in terms of translation difficulty and have similarly high translation ability requirements (a). Regarding chemical classes, differences in translation difficulty and thus translation requirements for students could be identified (b). In a multiple regression, person-related variables such as declarative knowledge and mental load could be identified as predictors of translation ability (c). Thereby, these findings provide first principles for dealing with learning opportunities that have translation requirements and possibilities for follow-up research.

Introducción. El objetivo del presente estudio es determinar si existe correlación entre los conocimientos sobre las consecuencias de la obesidad y el grado de actividad física de las personas. Métodos. Se realizó un estudio transversal analítico durante los años 2013 y 2014. Participaron 215 alumnos de pregrado seleccionados por conveniencia no relacionados a carreras del campo de la salud en una universidad de Lima, Perú. Se evaluó el grado de actividad física utilizando el International Physical Activity Questionnaire (IPAQ) y el nivel de conocimientos sobre consecuencias de la obesidad utilizando la escala Obesity Risk Knowledge-10 (ORK-10). También, se consignó las fuentes de información de donde obtuvieron el conocimiento para responder dicho cuestionario. Resultados. La mediana de edad fue 20 (rango intercuartílico=4) y 63% eran mujeres. De acuerdo al IPAQ, 53,9% realizaban actividad física alta, 35,4%, moderada y 10,7%, leve. Se encontró una correlación muy baja (rs=0,06) entre el puntaje del ORK-10 y la cantidad de equivalentes metabólicos/minuto consumidos por semana, pero no era significativa (p=0,38). Las personas informadas por medios de comunicación y por personal de salud obtuvieron mayores puntajes en el ORK- 10 que quienes se informaron por otras vías (p<0,05). Conclusiones. La correlación entre los conocimientos sobre consecuencias de la obesidad y el grado de actividad física es muy baja. Es necesario utilizar enfoques multidisciplinarios que incluyan todos los determinantes de la realización de actividad física para poder lograr cambios en la conducta de la población.