Base teórica: A doença de Parkinson (DP) é a segunda enfermidade neurodegenerativa mais frequente, crescendo proporcionalmente com o aumento da idade. É uma doença de comprometimento motor e não motor. Levodopa e agonistas dopaminérgicos (AD) são usados no tratamento da DP, permitindo um controle ótimo dos sintomas nos primeiros anos. Entretanto, em 5 anos, metade dos pacientes terão complicações motoras e nãomotoras induzidas pelo uso de antiparkinsonianos. Manifestações neuropsiquiátricas são frequentes, entre elas depressão, ansiedade, prejuízos cognitivos, sintomas psicóticos e transtorno de descontrole dos impulsos(DI). O DI é uma condição caracterizada pela falência em resistir a impulsos ou tentação de executar atos. O DI está associado ao uso de antiparkinsonianos, em especial, os agonistas dopaminérgicos A identificação desta condição é primordial para seu tratamento e estudo adequados. Na literatura atual, o questionário padrão-ouro foi validado na língua inglesa (QUIP), não existindo uma validação para língua portuguesa. Objetivo: Traduzir e validar o questionário QUIP-CS, em sua versão curta e aplicável no momento presente da DP, para lingua Portuguesa do Brasil Métodos: A versão curta da QUIP (QUIP-CS) foi traduzida para o Português por tradutor juramentado. Após, esta foi avaliada por 5 especialistas em DP no Brasil, sendo sugeridas pequenas correções. A versão corrigida em português foi retrotraduzida para o inglês por 2 tradutores juramentados nativos na língua original da escala (inglês), que compararam suas versões posteriormente, chegando-se a uma nova versão final neste idioma. Esta foi enviada ao autor da escala original, que concordou com esta versão, ou seja, foram mantidas as propriedades semânticas do instrumento. Após, a versão final em Português foi auto-aplicada em 65 indivíduos com diagnóstico de DP em tratamento no ambulatório especializado no HCPA, sendo que, de forma aleatória, para 30 foi aplicado um questionário de avaliação sobre o grau de dificuldade de compreensão de suas perguntas. Resultados: Em uma escala de 1 a 5 pontos, onde 1 era nenhuma compreensão das perguntas e 5, clara compreensão, a média de entendimento pelos pacientes foi de 4,06 +/- 0,69 DP. Conclusão: A avaliação desta versão foi considerada de fácil compreensão pelos próprios pacientes. O artigo para validação da tradução do conteúdo da versão em Português da QUIP-CS está em fase de revisão para publicação. / Background: Parkinson’s disease (PD) is the second most often neurodegenerative disease and proportionally growing with people aging. PD is a disease with motor and nonmotor clinical features. Levodopa and dopaminergic agonists (DA) are used for PD treatment, allowing an exquisite control of the motor symptoms during the first years. However, in five years, half patients will present motor or non-motor complications induced by cronic use of these medications. Neuropsychiatric symptoms are often, for example, depression, anxiety, cognitive impairment, psychotic symptoms and impulse control disorders (ICD). The ICD is characterized by failure on resisting an impulse or on performing an specific act. Identification of the PD affected patients is crucial for proper management and study of this condition. There is an already validated self-reported questionnaire for this purpose, the Parkinson's Disease Impulsive-Compulsive Disorders Questionnaire (QUIP), without equivalent in portuguese language. Objective: To translate and to validate the Portuguese short version of the gold-standard questionnaire for identifying ICDs PD affected patients, applicable at the current moment of PD Methods: QUIP-CS was first translated to Portuguese by a professional translator. This translated version was shown to 5 PD neurologist specialists. in Brazil, being suggested minor modifications on it. This new Portuguese revised version was back translated to English by two independent native English speakers. They were both asked to compare the version one another and checked for differences. Then, they contacted each other and got a final back translated version. This one was sent for the original author, that approved its new version comparing to his original and validated one, with no loss of it’s original properties. The Portuguese corrected version was applied to 65 patients in a random way at PD’s ambulatory at HCPA. From these, 30 were asked to answer a number that would represent their level of QUIP-CS questions’ comprehension. Results: In a 1 to 5 point scale, being 1 no comprehension and 5, total comprehension, the average was 4,06 +/- 0,69 DP. Conclusion: Our results on Portuguese version of QUIP-CS show that QUIP-CS translated and corrected version was easily understood and easily self-applied. The article is under revision to be submitted for publication.

Base teórica: A doença de Parkinson (DP) é a segunda enfermidade neurodegenerativa mais frequente, crescendo proporcionalmente com o aumento da idade. É uma doença de comprometimento motor e não motor. Levodopa e agonistas dopaminérgicos (AD) são usados no tratamento da DP, permitindo um controle ótimo dos sintomas nos primeiros anos. Entretanto, em 5 anos, metade dos pacientes terão complicações motoras e nãomotoras induzidas pelo uso de antiparkinsonianos. Manifestações neuropsiquiátricas são frequentes, entre elas depressão, ansiedade, prejuízos cognitivos, sintomas psicóticos e transtorno de descontrole dos impulsos(DI). O DI é uma condição caracterizada pela falência em resistir a impulsos ou tentação de executar atos. O DI está associado ao uso de antiparkinsonianos, em especial, os agonistas dopaminérgicos A identificação desta condição é primordial para seu tratamento e estudo adequados. Na literatura atual, o questionário padrão-ouro foi validado na língua inglesa (QUIP), não existindo uma validação para língua portuguesa. Objetivo: Traduzir e validar o questionário QUIP-CS, em sua versão curta e aplicável no momento presente da DP, para lingua Portuguesa do Brasil Métodos: A versão curta da QUIP (QUIP-CS) foi traduzida para o Português por tradutor juramentado. Após, esta foi avaliada por 5 especialistas em DP no Brasil, sendo sugeridas pequenas correções. A versão corrigida em português foi retrotraduzida para o inglês por 2 tradutores juramentados nativos na língua original da escala (inglês), que compararam suas versões posteriormente, chegando-se a uma nova versão final neste idioma. Esta foi enviada ao autor da escala original, que concordou com esta versão, ou seja, foram mantidas as propriedades semânticas do instrumento. Após, a versão final em Português foi auto-aplicada em 65 indivíduos com diagnóstico de DP em tratamento no ambulatório especializado no HCPA, sendo que, de forma aleatória, para 30 foi aplicado um questionário de avaliação sobre o grau de dificuldade de compreensão de suas perguntas. Resultados: Em uma escala de 1 a 5 pontos, onde 1 era nenhuma compreensão das perguntas e 5, clara compreensão, a média de entendimento pelos pacientes foi de 4,06 +/- 0,69 DP. Conclusão: A avaliação desta versão foi considerada de fácil compreensão pelos próprios pacientes. O artigo para validação da tradução do conteúdo da versão em Português da QUIP-CS está em fase de revisão para publicação. / Background: Parkinson’s disease (PD) is the second most often neurodegenerative disease and proportionally growing with people aging. PD is a disease with motor and nonmotor clinical features. Levodopa and dopaminergic agonists (DA) are used for PD treatment, allowing an exquisite control of the motor symptoms during the first years. However, in five years, half patients will present motor or non-motor complications induced by cronic use of these medications. Neuropsychiatric symptoms are often, for example, depression, anxiety, cognitive impairment, psychotic symptoms and impulse control disorders (ICD). The ICD is characterized by failure on resisting an impulse or on performing an specific act. Identification of the PD affected patients is crucial for proper management and study of this condition. There is an already validated self-reported questionnaire for this purpose, the Parkinson's Disease Impulsive-Compulsive Disorders Questionnaire (QUIP), without equivalent in portuguese language. Objective: To translate and to validate the Portuguese short version of the gold-standard questionnaire for identifying ICDs PD affected patients, applicable at the current moment of PD Methods: QUIP-CS was first translated to Portuguese by a professional translator. This translated version was shown to 5 PD neurologist specialists. in Brazil, being suggested minor modifications on it. This new Portuguese revised version was back translated to English by two independent native English speakers. They were both asked to compare the version one another and checked for differences. Then, they contacted each other and got a final back translated version. This one was sent for the original author, that approved its new version comparing to his original and validated one, with no loss of it’s original properties. The Portuguese corrected version was applied to 65 patients in a random way at PD’s ambulatory at HCPA. From these, 30 were asked to answer a number that would represent their level of QUIP-CS questions’ comprehension. Results: In a 1 to 5 point scale, being 1 no comprehension and 5, total comprehension, the average was 4,06 +/- 0,69 DP. Conclusion: Our results on Portuguese version of QUIP-CS show that QUIP-CS translated and corrected version was easily understood and easily self-applied. The article is under revision to be submitted for publication.

Subtext är en sanning gömd under ytan, som avslöjar en handling eller ords sanna mening. Hur kan en adaptionsprocess påverka subtexten då en bok tolkas om till film? Syftet med denna uppsats är att applicera en komparativ adaptionsanalys för att svara på frågan kring hur subtexten i en bok påverkas av att adapteras till film. Två kapitel och dess respektive filmscener analyseras därmed för att därefter peka ut dess subtext, detta från boken Dream Story och dess filmatisering Eyes Wide Shut. Skillnaderna i hur subtexten förmedlats pekas sedan ut i resultatet, där slutsatser kring adaptionsprocessen av subtext görs. Subtexten analyseras med hjälp av Linda Segers bok Writing Subtext: What Lies Beneath, vilket understöds med Thomas Denks teorier kring komparativa analyser i Komparativ metod – förståelse genom jämförelse. Resultatet har då pekat på att subtexten påverkats av att gå från en litterär till visuell tolkning, där mediespecifika detaljer påverkat berättandet. Dock har samma subtext i stor grad framförts i filmen, det har endast handlat om mediespecifika tolkningar.

Sentiment analysis is a field within machine learning that focus on determine the contextual polarity of subjective information. It is a technique that can be used to analyze the "voice of the customer" and has been applied with success for the English language for opinionated information such as customer reviews, political opinions and social media data. A major problem regarding machine learning models is that they are domain dependent and will therefore not perform well for other domains. Transfer learning or domain adaption is a research field that study a model's ability of transferring knowledge across domains. In the extreme case a model will train on data from one domain, the source domain, and try to make accurate predictions on data from another domain, the target domain. The deep machine learning model Convolutional Neural Network (CNN) has in recent years gained much attention due to its performance in computer vision both for in-domain classification and transfer learning. It has also performed well for natural language processing problems but has not been investigated to the same extent for transfer learning within this area. The purpose of this thesis has been to investigate how well suited the CNN is for cross-domain sentiment analysis of Swedish reviews. The research has been conducted by investigating how the model perform when trained with data from different domains with varying amount of source and target data. Additionally, the impact on the model’s transferability when using different text representation has also been studied. This study has shown that a CNN without pre-trained word embedding is not that well suited for transfer learning since it performs worse than a traditional logistic regression model. Substituting 20% of source training data with target data can in many of the test cases boost the performance with 7-8% both for the logistic regression and the CNN model. Using pre-trained word embedding produced by a word2vec model increases the CNN's transferability as well as the in-domain performance and outperform the logistic regression model and the CNN model without pre-trained word embedding in the majority of test cases.

Die europäische Fertigungsindustrie steht vor großen Veränderungen, die durch die zunehmende Nachfrage der Kunden nach maßgeschneiderten und/oder intelligenten Produkten, Industrie 4.0 Lösungen und Öffnung der Produktionsketten für Newcomer getrieben werden sowie durch die Veränderung hin zu Wertschöpfungsketten, in denen die Rollen von Lieferanten, Herstellern und Einzelhändlern verschwimmen. Diese sich dynamisch wandelnde Umwelt erfordert eine Anpassungsfähigkeit der Mitarbeiter, Fertigungswerkzeuge und Prozesse. Neue IKT-basierte Lösungen erleichtern einen Paradigmenwechsel, der Fabrikarbeiter als zukünftige "Wissensarbeiter" in den intelligenten Fabriken sieht, welcher nicht nur durch die Einführung neuer Technologien in die Fabriken gelingen kann. Arbeitsabläufe müssen umgestaltet werden und neue Ansätze zur kontinuierlichen Weiterentwicklung sind erforderlich. Bei der Verschiebung der Arbeitsaufgaben hin zur Wissensarbeit müssen bei der Anpassung der Arbeitsumgebungen zunehmend die Unterschiede bei den kognitiven Fähigkeiten berücksichtigt werden. Das hier vorgestellte Forschungsprojekt Factory2Fit zielt darauf ab, die menschlich zentrierte Fertigung auf ein neues Niveau zu bringen, indem den Mitarbeitern eine führende Rolle bei der Anpassung und Entwicklung ihrer eigenen Aufgaben zukommt. Das Hauptziel des Projektes ist es, adaptive Automatisierungslösungen zu entwickeln und zu pilotieren, die den Arbeitsablauf verbessern, den Arbeitnehmer dabei unterstützen, seine Kompetenzen zu entwickeln und die Mitarbeiter dazu befähigen, Wissen zu teilen und sich an der Gestaltung ihrer eigenen Arbeit zu beteiligen. Das Projekt Factory2Fit wird von Horizon 2020 (H2020/2014-2020), dem Programm für Forschung und Innovation der Europäischen Union, unter der Zuwendungsvereinbarung Nr. 723277 gefördert.

Studiens syfte är att öka förståelsen om arbetet med klimatanpassning och hur frågan kan integreras i kommunala sektorer som inte har klimatanpassning som sitt främsta uppdrag. Genom att öka kunskapen om det praktiska arbetet inom utbildnings- samt vård och omsorgssektorer bidrar studien med insikter om faktorer som påverkar effektiviteten av integrering av klimatanpassning. Arbetet bygger på totalt 10 semistrukturerade intervjuer med nyckelpersoner inom kommunala utbildnings- samt vård- och omsorgssektorer i Norrköping. Intervjuerna gav en bred bild av medarbetarnas erfarenheter och insyn genom deras dagliga arbete. Materialet analyserades och diskuterades i relation till vad tidigare forskning kommit fram till. Resultatet visar att arbetet med klimatanpassning inom kommunen har kommit långt, men att det saknas en klar strategi för hur kommunens riktlinjer för klimatanpassning ska integreras i organisationen. Identifierade faktorer för en effektiv implementering är tydligt uppsatta mål, koordination, politiskt engagemang, ökade och riktade ekonomiska resurser samt kunskapsutbyte. / The purpose of the study is to increase the understanding of the work with climate adaptation and how the issue can be integrated in municipal sectors that do not have climate adaptation as their main task. By increasing the knowledge of the practical work in education- as well as care and nursing sectors, the study add insights into factors that influences the effectiveness of the integration of climate adaptation. The work is based on 10 semi-structured interviews with key staff within education as well as care and nursing sectors in Norrköping municipality. The interviews provided a broad overview of experiences and insights by the staff through their daily work. The material was analyzed and discussed in relation to what previous research had concluded. The results show that the work with climate adaptation within the municipality has come a long way, but that there is no clear strategy for how the municipal guidelines for climate adaptation should be integrated into the organization. Found factors for an effective implementation are clearly set goals, coordination, political commitment, increased and targeted financial resources and knowledge exchange.

Benny Anderssons och Björn Ulvaeus musikal Kristina från Duvemåla är baserad på Vilhelm Mobergs utvandrarepos och sågs mellan åren 1995–1999 av över en miljon besökare. Denna undersökning har med utgångspunkt i de teoretiska termerna adaption, ledmotiv och folkton analyserat dels hur den litterära textens teman och handling har adapterats till musikalen i form av sångtexterna och dels hur upphovsmännen har valt att musikaliskt förmedla Karl Oskars och Kristinas kärlek samt Kristinas hemlängtan. Begreppen ”aural equivalents” och ”musically voiced” har varit ledord i undersökningen, likaså dramaturgiska teman. Undersökningen är både en adaptionsanalys och en musikalisk analys. Enligt det hermeneutiska tankesättet pendlar undersökningen mellan detaljerade analyser av utvalda låtar och låttexter och mer översiktliga analyser av musikalen som helhet i förhållande till Vilhelm Mobergs utvandrarepos. Det står klart att upphovsmännen har förvaltat originalverkets berättelse väl, men de har också gjort en del perspektivförändringar då många av karaktärerna har fått mindre utrymme än i böckerna, medan karaktären Kristina tar mer plats i musikalen. Upphovsmännen har använt sig av ledmotiv och folkton som ”aural equivalents” för att både skildra kärleken mellan Kristina och Karl Oskar och Kristinas hemlängtan. Ledmotivens symbolik är tematisk, snarare än kopplad till enskilda karaktärer, vilket i sin tur har resulterat i en komplex ”väv av ledmotiv”. Folkton och direkta inlån från traditionell folkmusik har använts för att gestalta Kristinas hemlängtan och för att placera berättelsen i tid och rum. Till sist reflekteras det över det faktum att även utvandrareposet är en adaption av den svenska utvandringen till Amerika under 1800-talet. Denna undersökning hoppas kunna bidra till forskningen kring hur ett originalverk påverkas av att adapteras till musikteaterns förutsättningar och konventioner och på vilka sätt en musikalkompositör musikaliskt kan gestalta de dramaturgiska teman som en musikal består av.

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Ausgehend vom Bedarf nach verbesserten Bahnlaufregelungen werden eine Reihe regelungstechnischer Maßnahmen auf ihre grundsätzliche Tauglichkeit hin untersucht. Vorhandene Modellbildung des Bahnlaufes und der Bedruckstoffe wird verfeinert und konsequent für Regelungsansätze genutzt. Für rollendrucktypische Anlagenkonfigurationen wird eine Modellbibliothek entwickelt und eingesetzt. Die übergreifende Betrachtung von Prozeßdynamik, Regelungstechnik, Antriebstechnik, Werkstoffeigenschaften und verfahrenstechnischen Aspekten erschließt bedeutendes Optimierungspotential. Die systemanalytische Betrachtung des Förderprozesses geschieht mit den Methoden der theoretischen und experimentellen Modellbildung. Die vorliegende Arbeit erweitert Standardverfahren der Reglersynthese sowie der parameteroptimalen Streckenadaption, wobei die Struktursynthese auf der Auswahl und Kombination geeigneter Standardstrukturen beruht.

Adaptability is an intrinsic property of software systems that require adaptation to cope with dynamically changing environments. Achieving adaptability is challenging. Variability is a key solution as it enables a software system to change its behavior which corresponds to a specific need. The abstraction of variability is to manage variants, which are dynamic parts to be composed to the base system. Run-time variability realizes these variant compositions dynamically at run time to enable adaptation. Adaptation, relying on variants specified at build time, is called anticipated adaptation, which allows the system behavior to change with respect to a set of predefined execution environments. This implies the inability to solve practical problems in which the execution environment is not completely fixed and often unknown until run time. Enabling unanticipated adaptation, which allows variants to be dynamically added at run time, alleviates this inability, but it holds several implications yielding system instability such as inconsistency and run-time failures. Adaptation should be performed only when a system reaches a consistent state to avoid inconsistency. Inconsistency is an effect of adaptation happening when the system changes the state and behavior while a series of methods is still invoking. A software bug is another source of system instability. It often appears in a variant composition and is brought to the system during adaptation. The problem is even more critical for unanticipated adaptation as the system has no prior knowledge of the new variants. This dissertation aims to achieve anticipated and unanticipated adaptation. In achieving adaptation, the issues of inconsistency and software failures, which may happen as a consequence of run-time adaptation, are evidently addressed as well. Roles encapsulate dynamic behavior used to adapt players representing the base system, which is the rationale to select roles as the software system's variants. Based on the role concept, this dissertation presents three mechanisms to comprehensively address adaptation. First, a dynamic instance binding mechanism is proposed to loosely bind players and roles. Dynamic binding of roles enables anticipated and unanticipated adaptation. Second, an object-level tranquility mechanism is proposed to avoid inconsistency by allowing a player object to adapt only when its consistent state is reached. Last, a rollback recovery mechanism is proposed as a proactive mechanism to embrace and handle failures resulting from a defective composition of variants. A checkpoint of a system configuration is created before adaptation. If a specialized bug sensor detects a failure, the system rolls back to the most recent checkpoint. These mechanisms are integrated into a role-based runtime, called LyRT. LyRT was validated with three case studies to demonstrate the practical feasibility. This validation showed that LyRT is more advanced than the existing variability approaches with respect to adaptation due to its consistency control and failure handling. Besides, several benchmarks were set up to quantify the overhead of LyRT concerning the execution time of adaptation. The results revealed that the overhead introduced to achieve anticipated and unanticipated adaptation to be small enough for practical use in adaptive software systems. Thus, LyRT is suitable for adaptive software systems that frequently require the adaptation of large sets of objects.