• Refine Query
  • Source
  • Publication year
  • to
  • Language
  • 281
  • 125
  • 93
  • 48
  • 26
  • 25
  • 20
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • Tagged with
  • 776
  • 108
  • 96
  • 80
  • 74
  • 70
  • 63
  • 60
  • 57
  • 55
  • 54
  • 54
  • 48
  • 44
  • 43
  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
761

Падение и возрождение «града и мира» в литературе XV-XVII вв. : магистерская диссертация / The fall and rebirth of the "city and the world" in the literature of the XV–XVII centuries

Мамыкина, Е. Е., Mamykina, E. E. January 2023 (has links)
Тема данной диссертации – «Падение и возрождение “града и мира” в литературе XV-XVII вв.», сама работа посвящена осмыслению темы падения городов на материале «Повести о разорении Рязани», «Повести о взятии Царьграда» и «Казанской истории». В рамках исследования были выделены общие и особенные мотивы, использующиеся в соответствии с авторским целеполаганием, соотнесена сюжетная составляющая памятников в соответствии с проблемами исторических ситуаций. Для более полного понимания вопроса были изучены некоторые аспекты урбанистики, что позволило увидеть своеобразие средневекового взгляда на город, а также были привлечены тексты Священного писания для более полного понимания всех смыслов, вкладываемых средневековым человеком в понятие города. / The topic of this dissertation is "The fall and rebirth of the "city and the world" in the literature of the XV–XVII centuries", the work itself is devoted to understanding the theme of the fall of cities on the material of "The Tale of the destruction of Ryazan", "The Tale of the capture of Tsargrad" and "Kazan History". Within the framework of the study, general and special motives used in accordance with the author's goal-setting were identified, the plot component of monuments was correlated in accordance with the problems of historical situations. For a more complete understanding of the issue, some aspects of urbanism were studied, which made it possible to see the uniqueness of the medieval view of the city, and the texts of the Holy Bible were also involved for a more complete understanding of all the meanings put by a medieval person into the concept of a city.
762

Here Lies the Defendant : The Claimant-friendly Narrative in the Court’s Case-law on Special Jurisdiction under the Brussels Regime

Skog Sand, Simon January 2024 (has links)
The EU jurisdictional scheme, known as the “Brussels Regime”, confers competence to national courts to adjudicate over international matters. The main rule in Article 4(1) of the Brussels Ibis Regulation sets out that the defendant should generally be sued in the courts of the Member State where he is domiciled. For certain subject matters, the scheme allows the action to be brought elsewhere. The raison d’être is to provide an adequate counterbalance to the one-sided rule of Article 4(1). Articles 7(1) and (2) enable the claimant to launch the suit, “in matters relating to a contract”, at the court of the Member State where the contractual obligation was to be fulfilled, and, in “matters relating to tort”, in the courts for the place where the harmful event occurred. Whether to invoke Article 7 is entirely the claimant’s choice, but the final decision on its interpretation is vested in the Court. Thereby, the manner in which the Court views the provisions will effectively decide the extent of the claimant’s choice to invoke so-called special jurisdiction. It also means that greater emphasis on special jurisdiction will reduce the importance of the main rule in Article 4. Conversely, if the Court were to interpret Article 7 narrowly, its intended effect within the system would be denied. In both cases, the balance between Articles 4 and 7 has been upset. In the former case, the claimant is favoured because of the increased possibilities to choose the forum for the dispute, while in the latter case, the defendant is favoured because he retains the advantage of litigating in his home turf. The starting point for this essay is this very idea of a purported balance between litigants’ interests in EU cross-border litigation. The thesis analyses whether the Court’s case-law on general vis-à-vis special jurisdiction has transitioned from being generally defendant-friendly to claimant-friendly. It is argued that already from the first judgments rendered on the original Brussels Convention in 1976, increasingly more disputes have been launched at special fora, which has amounted to a claimant-friendly scheme. It is also argued that this development has been at the expense of the defendant. Greater choice for the claimant means in turn that the defendant’s ability to foresee before what courts he may be sued has been largely impaired. The thesis highlights how this imbalance is the result of inherent challenges in the Brussels Regime, particularly in relation to how the relevant connecting factors are designated. It is proposed that the unwanted effects of the Court’s practice as well as the shortcomings of the scheme itself are to be considered in the Commission’s evaluationof the Brussels Ibis Regulation, which is presently in the works.
763

Pengar, piller och policy : En marknadsanalys av den svenska och italienska antibiotikamarknaden och effekterna på antimikrobiell resistens / Pennies, pills and policy : A market analysis of the Swedish and Italian antibiotic market and the effects on antimicrobial resistance

Jonsson, Julia, Åkerman, Ylva January 2024 (has links)
Över - eller felanvänd antibiotika leder till ökad risk för antimikrobiell resistens. När en bakterie har blivit resistent så har det skapats en motståndskraft, vilket gör antibiotikan verkningslös. Antibiotika är ett livsnödvändigt läkemedel, då det används rutinmässigt vid kirurgiska ingrepp och för att bekämpa bakteriella infektioner. Det finns inget alternativt läkemedel, vilket innebär att om antibiotika blir verkningslös är de globala konsekvenserna katastrofala. Den negativa utvecklingen har resulterat i att EU - kommissionen klassificerar antimikrobiell resistens (AMR) som ett av de tre största hälsohoten i världen. Internationella organisationer har presenterat krav och rekommendationer för hur länder ska hantera antibiotika och dess resistens, vilket har implementerats olika väl. Sverige har en av de lägsta frekvenserna av resistenta bakterier inom EU, medan Italien har en av de högsta. Hypotesen är att de nämnda ländernas resistensgrad har ett samband med hur väl man implementerat strukturer, regleringar och strategier på antibiotikamarknaden. Hypotesen undersöks genom en marknadsanalys baserat på en anpassad SCP - modell där Sveriges och Italiens respektive utfall värderas.  I utfallen framgår det att Sveriges antibiotikamarknad är mer kontrollerad än den italienska. En mer styrd marknad skapar möjligheten att kontrollera antibiotikakonsumtionen, vilket i sin tur bestämmer resistensgraden. Å andra sidan innebär en mer kontrollerad marknad att läkemedelsföretagens vinstgaranti försvinner, dessa kan tvingas lämna marknaden vilket leder till brist på antibiotika. En mindre styrd marknad gynnar däremot läkemedelsföretagen då det finns en vinstgaranti och en större konsumtion. Nackdelen är att resistensgraden ökar. I marknadsanalysen presenterades även att länderna skiljer sig i ansvarsfördelning, då hälso - och sjukvård är mer decentraliserad i Italien jämfört med Sverige. Strukturer, regleringar och strategier för att hantera AMR implementerades nationellt i Sverige, medan det i Italien är upp till varje region att agera. Italiens ansvarsfördelning resulterar i att resistensgraden skiljer mellan det södra och norra regionerna, då regionernas styren skiljer i kvalitet.  Slutligen lämnas förslag på förändringar för respektive land. Sverige behöver erbjuda en vinstgaranti för läkemedelsföretagen för att kunna säkerställa tillgången till antibiotika. Det råder brist idag, vilket medför att marknaden behöver bli mer attraktiv för företagen. Italien behöver förändra ansvarsfördelningen och införa nationella strukturer, regleringar och strategier. Det kommer öka möjligheten för mer påkostade åtgärder som gäller för alla regioner, vilket hanterar AMR mer effektivt. / An excessive or incorrect use of antibiotics can result in an increased prevalence of antimicrobial resistance. When a bacterium has become resistant, resilience against antibiotics is created, which makes the drug ineffective. Antibiotics are vital drugs, as they are routinely used in surgical procedures and combat bacterial infections. Often, there is no alternative medicine, which means that when an antibiotic becomes ineffective, the consequences are catastrophic for the global population. The global increase in resistance has forced the European Commission to classify antimicrobial resistance (AMR) as the world's third largest public health threat. International organizations have presented requirements and recommendations for how countries should handle antibiotics and their resistance. However, it has been the nation’s responsibility to implement these changes. Sweden has one of the lowest prevalence of antibiotic resistant bacteria in the EU, while Italy has one of the highest. The essay hypothesizes that the mentioned countries' degree of resistance can be explained by how well structures, regulations, and strategies are implemented. The hypothesis is evaluated through a market analysis where a reconstructed SCP - model is applied where Sweden’s and Italy’s respective performance is presented. The essay found that the Swedish antibiotic market is more regulated than the Italian. A more regulated market creates the opportunity to control antibiotic consumption, which further controls the degree of resistance. On the other hand, an over - regulated market means that there is no guarantee of profit for the pharmaceutical companies which often forces the companies to leave the market. A less regulated market benefits pharmaceutical companies as there is a guarantee of profit and larger consumption. The disadvantage is that the degree of resistance increases. In the market analysis, it is also presented that the countries differ in the distribution of responsibilities, as healthcare is more decentralized in Italy compared to Sweden. The structures, regulations, and strategies to manage AMR were implemented nationally in Sweden, while in Italy it is up to each region to act. Italy's division of responsibility results in that the degree of resistance differs between the southern and northern regions, as the regions' governments differ in quality. Finally, the essay presents proposals for changes for each country. Sweden should offer a profit guarantee for pharmaceutical companies, as they need access to a broad selection of antibiotics. The existing shortage should be dealt with, which is why the market needs to be more attractive for companies. Italy needs to change the distribution of responsibilities and introduce national structures, regulations, and strategies. This will increase the possibility of more costly measures that apply to all regions, which will manage AMR more effectively.
764

Paradoxia epidemica in the art of Pieter Bruegel the Elder : an investigation into sixteenth-century parody

Cornew, Clive 01 1900 (has links)
Pieter Bruegel the Eider's paintings De verkeerde wereld, Het gevecht tussen Karnava/ en Vasten, Luilekker/and, Dulle Grief and Landschap, met Icarus' val are interpreted as sixteenth-century parodies using the paradoxia epidemica as a tropic means for interpreting the artist's wit, irony, parody and picaresque stance towards his source material and his milieu. Where applicable, other works relating to a particular argument are also discussed. As a result of this investigation, an original contribution has been made in the literature on both Bruegel and parody as a form of visual communication. / Art History, Visual Arts & Musicology / M.A. (History of Art)
765

SOUS LE SPECTRE DU PÈRE: POÉTIQUE ET POLITIQUE DE LA DÉPENDANCE ET DU SEVRAGE DANS LE ROMAN POSTCOLONIAL AFRICAIN

SHAMBA, MBUMBURWANZE N 27 June 2011 (has links)
This thesis analyzes the major theme of ‘postcolonial genealogy’ in portraying the African bending under the weight of colonial history in Le vieux nègre et la médaille, Une vie de boy of Ferdinand Oyono and Le Chercheur d’Afriques of Henri Lopes. Being a product of a colonial Genesis, the African character runs behind the colonizer’s mirror through his Civilizing Mission. René Girard’s ‘double bind’ theory explains how this cultural assimilation is, in Le vieux nègre et la médaille and Une vie de boy, a dead end because the colonizer needs a subordinate and not an equal. The cohabitation of a black housewife with the French Commander in Le Chercheur d’Afriques should be seen as simply an allegory of postcolonial Africa’s dependency on the West. The consequences of the feminization of the African continent are enormous in the post-colonial imaginary. While the colonizer had conquered Africa with his Herculean body, in Oyono’s novels, his Fall is obtained through the aesthetics of Bakhtinian ‘rabaissement’ which degrades his ‘grotesque body’ to that of the colonized. The colonizer and the colonized are neutralized and leveled in their perishable bodies, thus, making futile the Civilizing Mission that operated by ranking races. Power is never total. It is always imperfect, and can never destroy a subjectivity that resists it. In Oyono’s novels, the Fall of the colonial Father is also obtained through the inquisitive gaze that the colonized return back to the colonizer, and through their ‘subversive mimicry’ that parodies his codes. In Une vie de boy and Le Chercheur d’Afriques, the ‘son-Father’ relationship between the hero and the colonial Father, is also symbolic of the ‘Africa-West’ rapports. Living under the specter of the Father, the son has to negotiate his survival between weaning and parricide. The biological miscegenation in Le Chercheur d’Afriques is a metaphor of the ‘rhizome identity’ of the postcolonial African who renounces both the Fathers of Negritude and those of the Civilizing Mission. / Thesis (Ph.D, French) -- Queen's University, 2011-06-24 12:43:30.006
766

Paradoxia epidemica in the art of Pieter Bruegel the Elder : an investigation into sixteenth-century parody

Cornew, Clive 01 1900 (has links)
Pieter Bruegel the Eider's paintings De verkeerde wereld, Het gevecht tussen Karnava/ en Vasten, Luilekker/and, Dulle Grief and Landschap, met Icarus' val are interpreted as sixteenth-century parodies using the paradoxia epidemica as a tropic means for interpreting the artist's wit, irony, parody and picaresque stance towards his source material and his milieu. Where applicable, other works relating to a particular argument are also discussed. As a result of this investigation, an original contribution has been made in the literature on both Bruegel and parody as a form of visual communication. / Art History, Visual Arts and Musicology / M.A. (History of Art)
767

La culture matérielle de la Mésopotamie du Nord et de ses voisins, d’après l’étude de la céramique, de l’Uruk récent au Bronze ancien I/II / Material culture of Northern Mesopotamia and its Neighbours, according to ceramic study, from Late Uruk Period to Early Bronze Age I/II

Ossman, Mouheyddine 26 January 2013 (has links)
Durant le IVe millénaire, la Mésopotamie et ses voisins ont été reliés via un vaste réseau commercial, établi par des Urukéens lors de leur expansion en Iran et dans le Nord mésopotamien. À la fin du IVe et au début du IIIe, la Mésopotamie et ses voisins ont connu une phase de crise dont les causes nous sont toujours obscures en raison de l’absence des documents écrits remontant à cette phase. A cette phase, le réseau commercial urukéen et la colonisation urukéenne en Iran et en Mésopotamie du Nord, s’étant effondrés, les sites urukéens ont été abandonnés, ainsi qu’un grand nombre de sites indigènes qui ont été abandonnés. Le contact entre le Nord et le Sud mésopotamien fut suspendu. Pourtant, d’autres sites furent fondés que ce soit en Iran ou en Mésopotamie. Bien que la culture céramique mésopotamienne ne se soit modifiée profondément à cette phase cruciale, des traditions peintres réapparaissent soudainement alors que les Mésopotamiens les avaient abandonnées depuis 9 siècles (au Post-Obeid). Trois aires à céramique peinte apparaissent en Mésopotamie : en Irak du centre, de l’Est, du Nord (horizon de Ninive 5) et l’Iran a employé massivement la peinture. Cependant, le Sumer a conservé les traditions urukéennes qui ne connaissent pas de peinture. A noter que la peinture en Iran a été employée avant et durant l’expansion urukéenne. De plus, il semble avoir existé un corridor de contact reliant le West iranien aux trois zones à peinture en Mésopotamie. Mais comment peut-on expliquer ce phénomène de la réapparition de la peinture en Mésopotamie centrale et du Nord : s’agit-il des déplacements des groupes iraniens en Mésopotamie, ou des simples influences ? On ne peut pas traiter de la question de la fin du IVe/début du IIIe millénaire sans confronter, d’une part au problème concernant le destin des Urukéens. Ces derniers ont vécu plus de 4 siècles dans la périphérie durant l’expansion. Et d’autre part on est confronté au problème de la fondation des sites urbain aux touts début du 3e millénaire (Mari, Terqa, Kharab Sayyar et Chuera).Pour répondre à ces questions, nous avons choisi des sites-clés en Iran et en Mésopotamie. Leur céramique (et d’autre matériel) est étudié tout d’abord dans leur position stratigraphique, site par site, puis selon leur répartition dans l’espace. Au même temps, cette étude strato-céramique a été combinée avec une étude portée sur les changements dans l’occupation dans l’espace (abandon et fondation) et sur les transformations culturelles, surtout en Iran du Nord-Ouest et de l’Ouest où le phénomène de l’expansion transcaucasienne s’étend jusqu’au Kermanshah et le Nord du Luristan dans le Zagros central).Basant sur des comparaisons céramiques et sur d’autres aspects archéologiques, nous avons tenté de corréler entre la stratigraphie des sites étudiés. Nous avons évité de faire d’un site ou d’une région le « centre du monde ». Nous avons plutôt regardé chaque site et région à partir de ses voisins. A la fin de chaque partie ou chapitre, nous avons relié entre les régions étudiées, du point de vue culturel, stratigraphique et occupationnel, pour tenter de tirer une conclusion historique concernant le passage entre le IVe et le IIIe millénaires.Vers 2700-2600 av. J.-C., les traditions peintes disparaissent à nouveau de la Mésopotamie, au moment où le contact a été rétabli entre les Sumériens et le Nord mésopotamien (Mari-Brak-Chuera). Concernant cette reprise de contact, nous mettons plus l’accent sur les changements observés dans la stratigraphie (sites abandonnés et/ou incendiés) pour parler d’un phénomène que nous avons appelé la « Sumérianisation ». Nous avons tenté de repérer ce phénomène par le biais de quelques inscriptions datées du Dynastique Archaïque III (vers 2600-2500 av. J.-C.). / During the 4th millennium, Mesopotamia and its neighbours were connected by a vast trade network which was established by Urukians throughout their expansion into Iran and Northern Mesopotamia. At the end of the 4th millennium and at the beginning of the 3rd, all those regions faced a phase crisis whose causes are unknown for us because of the absence of the written documents dated to this phase. At this phase, the Uruk trade network and colonization in Iran and Northern Mesopotamia were collapsed. Uruk sites have been abandoned. In addition, a large number of indigenous sites were abandoned. The contact between Northern and Southern Mesopotamian was suspended. However, other sites were founded in Iran and Mesopotamia. Although, with this crucial phase, the Mesopotamian ceramic culture did not change deeply, the painting traditions reappeared suddenly whereas the Mesopotamian had abandoned them since 9 centuries c. (in Post-Obaid).Three zones with painted ceramics appear in Mesopotamia: centre of Iraq, Eastern Iraq, North Iraq and North-Eastern Syria. Also, Iran employed massively the painting. However, the land of Sumer conserved the Uruk traditions which aren’t painted. Worthily to be noted that the painting traditions existed in Iran before and even during the Uruk expansion. Moreover, a corridor of contact seems to have existed linking Western Iran to those three zones. But, how can one explain this reappearance phenomenon of this painting in the centre and North Mesopotamia: is-it because of the displacements of the Iranian groups into Mesopotamia or is it a simple influence? Likewise, one cannot treat the question of the end of the 4th millennium without being confronted with the problem of the destiny of the Urukians colonists. Those latter lived in the periphery more than 4 centuries during the expansion. On the other hand, one is confronted with the problem of the foundation of urban-cities with the all beginning of the 3rd millennium (Mari, Terqa, Kharab Sayyar and Chuera). To answer these questions, we chose site-keys in Iran and Mesopotamia. First of all, we studied, site by site, their ceramic (and others materials) according to their stratigraphical position (strato-ceramic), and then based on their distribution in the landscape. At the same time, those strato-ceramics analyses have been combined with another study concerning changes in the occupation of landscape (abandonment and foundation), and the cultural transformations, especially for the North-Western and Western Iran where the transcaucasian expansion extends to Kermanshah and Northern Luristan in central Zagros.Based on ceramic comparisons and on other archaeological aspects, we attempted to correlate between the stratigraphy of the studied sites. We avoided making of a site or of a region the “Center of the World”. We rather looked at each site and region starting from its neighbours. At the end of each part or chapter, we linked between the studied regions, from the cultural point of view, stratigraphic and occupational, in order to try to draw a historic conclusion concerning the passage between the 4th and the 3rd millennium.Towards 2700-2600 B.C., the painting traditions disappeared once again from Mesopotamia, at the time when the contact was restored between the Sumerians and Northern Mesopotamian (Mari-Brak-Chuera). For this resumption of contact, we set the accent more on the changes observed in the stratigraphy (abandoned sites or burned) to speak about a phenomenon which we called “the Sumerianisation”. Moreover, we tried to identify this phenomenon by the means of some inscriptions dated to the Dynastic archaic III (towards 2600-2500 B. C.).
768

Etude du contrôle postural chez l'homme : analyse des facteurs neurophysiologiques, biomécaniques et cognitifs, impliqués dans les 500 premières millisecondes d'une chute / The descent phase of falls : neuromuscular, mechanical and cognitive factors in the first five hundred milliseconds of a fall

Le Goïc, Maëva 22 November 2013 (has links)
La chute chez les seniors constitue un problème de santé publique. Citée comme la seconde cause de décès accidentel dans le monde, elle concerne un tiers des Français de plus de 65 ans. Les séquelles physiques et fonctionnelles qui en résultent, les conséquences psychosociales nuisibles pour la qualité de la vie, la perte d’autonomie et son coût de prise en charge justifient l’attention qui lui est actuellement portée. Du point de vue du chercheur, les interprétations sous-jacentes à la surexposition des personnes âgées au risque de chute restent controversées, notamment parce que la compréhension de la coordination dynamique corporelle et de l’implication corticale lors du contrôle de l’équilibre est encore limitée. L’étude de la chute et des mécanismes qui y conduisent présente donc un double intérêt, fondamental et sociétal. Une chute survient si deux conditions sont réunies. La première est la perte initiale de l’équilibre, un ‘pré-requis’ qui peut toucher la population entière dans son quotidien. La seconde est un échec des mécanismes de rééquilibration, c’est à dire de la stratégie de réponse mise en œuvre pour compenser la déstabilisation : comment s’opère la sélection d’une stratégie de rattrapage, à partir de quelle appréciation du contexte et des informations sensorielles disponibles est-elle choisie ? qu’est ce qui assure son opérationnalité et garantit le rattrapage ou signe au contraire son échec ?...Pour répondre à ces questions, nous nous sommes donc intéressés à ce moment critique où il est encore possible de modifier l’issue finale par des ajustements posturaux et des actions motrices rapides et adéquats chez une population de jeunes adultes. La première étude est une analyse globale de la phase précoce d’une chute -abrégée par un harnais- (soit quelques centaines de millisecondes après la perturbation), afin d’évaluer la capacité du sujet à réagir à une perturbation imprévue et de développer des stratégies garantissant une protection efficace. Cette première étape se propose d’identifier les indicateurs discriminants et prédictifs d’une chute et d’un rattrapage au niveau neurophysiologique et biomécanique. Cette étude a également permis de mettre en évidence la présence d’un délai temporel incompressible appelé « phase passive », source de contraintes spatio-temporelles à l’expression complète d’une réponse posturale adaptée. Dans la seconde étude, de modélisation, nous avons élaboré un modèle mécanique personnalisé, construit à partir de radiographies tridimensionnelles non invasives du corps entier. Cette modélisation nous a permis d’analyser la contribution relative de propriétés biomécaniques passives et des synergies musculaires actives en jeu pendant les perturbations récupérables de l’équilibre ou non en comparant les résultats expérimentaux (‘réels’) obtenus à l’aide d’un dispositif asservi pour provoquer des chutes de plain-pied et la réponse théorique prédite (‘simulée’) à l’aide du modèle. Les résultats obtenus permettent de confirmer que le comportement du corps est en phase précoce-dicté par ses propriétés mécaniques, et peut être assimilé à un modèle simplifié. Après avoir mis en évidence l’existence d’une phase inertielle d’une durée équivalente à la moitié du temps disponible avant l’impact, notre questionnement s’est orienté vers le traitement de l’information en-cours lors de cette phase afin d’évaluer la contribution corticale alors que la réponse posturale évolue. La troisième étude consiste principalement à appréhender la charge cognitive impliquée dans le contrôle sensori-moteur, en particulier lors d’une chute, à l’aide du paradigme de double-tâche. En conclusion, à travers une approche pluridisciplinaire, les résultats obtenus dans cette thèse permettent d’émettre des recommandations intéressantes pour une prévention et une rééducation adaptée dans le but de contribuer à l’amélioration de la qualité de vie des personnes âgées. / A better understanding of what happens during an unintentional fall is relevant in preventing their occurrence. A fall is due to a failure of compensatory reactions to recover from postural perturbations during the descent phase which starts at the subject loss of balance point and lasts no more than 700-1000milliseconds [Hsiao, 1998]. The aim of the first study was to compare the biomechanical and muscular behavior during the pre-impact phase during non-recoverable falls and successful recovery trials. The experimental study aimed to evaluate the subject’s ability to distinguish in the first 500 milliseconds following the onset of perturbation a low-threatening perturbation from a high challenging one and can then predict the scenario that will more likely lead to a fall using specific motor strategies. In such a challenging task, we hypothesized that the constraints imposed by the biomechanical properties ultimately determine the ability to trigger efficient muscle activities. Full body 3D kinematics and associated muscle activities were collected in 30 young healthy subjects during fast and slow unpredictable multidirectional support-surface translations. 40 cm support-surface translations were used to evoke the balancing reactions (0,35 vs 0,9 m/s during resp. 1000 vs 500 millisecond The perturbation velocities were selected so that successful recovery should occur in milder trials whereas fast trials were sufficiently challenging to trigger non-recoverable falls. Analyses focused on the spatial and temporal characteristics of the Centre of Mass, angle variations, recovery step characteristics, and EMG activities (onset latencies and amplitudes) across each trial and muscle. Moreover, a 17-segment numerical and personalized model was created, based on stereoradiographic head to feet X-ray images followed by 3D-reconstruction methods to assess subject-specific geometry and inertial parameters. The outputs resulting from simulated falls allowed us to discard the contributions of the passive (inertia-induced) versus the active mechanisms (feedback-controlled and time-delayed neuromuscular components) of the response. The first outcome of that study was that the fall could be divided in distinct phases. For about 200 milliseconds following the onset of platform translation, the head remained stable in space. Similarly, the comparison with the simulated data supported that the CoM displacement matched the subject-dependant mechanical model. During a second phase of the fall, despite the fact that automated muscle postural synergies started at 80 milliseconds after perturbation onset, the trajectory of the body appeared to be exclusively dictated by its biomechanical properties. Later, muscle activities influenced the body trajectories, which consequently differed on a trial-to-trial basis. The simulation was in good agreement with the experimental results. The specificity of the postural response resulting in a strategy chosen to avoid a fall thus appeared in a late-phase, which can be explained because during a fall, the subjects had to prepare to the impact on the basis of sensory information that were not redundant but available in a sequential order: proprioceptive information appearing first while vestibular and visual information continued to signal a stabilized head in space. The sole proprioceptive information would be insufficient to trigger rapid and appropriate postural response. Moreover, in accordance with our results suggesting the importance of the late-phase and on-line controlled responses, a long inertial passive phase in the fast trials does not allow a large spatiotemporal window for compensatory reactions to occur. These could not only depend on the previously described automated postural synergies because the time constraints imposed by biomechanics permit in principle volitional motricity to play an important role very early in the fall. (...)
769

Off-Host Biology and Ecology of Immature Gulf Coast Ticks (Amblyomma Maculatum Koch) in Mississippi

Portugal, Jose Santos 06 May 2017 (has links)
Little is understood about off-host behavior and ecology of immature Amblyomma maculatum Koch (Gulf Coast tick). A more complete understanding of this tick is essential to protect human and animal health. My research focused on seasonality and distribution of immatures in Mississippi, potential suitability of some insect and human hosts to larvae, and aspects of nymphal questing behavior. A single larva was collected (third off-host collection reported) when sampling A. maculatum habitat using a novel device. Collection of this larva in November expands the stage’s known seasonality and confirmed a prediction concerning seasonality of larval A. maculatum. Low frequency of immatures (8.3%) confirmed that they’re incredibly difficult to collect off-host. Nymphal collections peaked in March, and known seasonality was extended for both nymphs and adults. I examined known records, elucidating seasonality and distribution of A. maculatum in Mississippi. Either multiple generations per year or diapause are responsible for observed bi-modal distribution of immature collections. Additionally, I compiled the most extensive host record of immature A. maculatum in Mississippi and investigated seasonality patterns using USDA plant hardiness zones. I compiled the most complete record of ticks found on arthropods. Amblyomma americanum and A. maculatum were both confirmed to crawl onto arthropods, giving support to occasional, unintentional dispersal by phoresy. There was no conclusive evidence that larval A. maculatum feed on arthropods, however data supported feeding by larval A. americanum. These results have interesting implications regarding evolution of pathogens/endosymbionts. I provided the first evidence that larval A. maculatum can attach to humans. Rickettsia parkeri, a human pathogen transmitted by this species has recently been shown to be capable of transovarial transmission. Therefore, larval A. maculatum may provide another avenue of transmission. I have demonstrated that A. maculatum are difficult to collect off-host in part because they prefer to quest low to the ground. In choice studies, 5-cm-tall stems were most likely to be occupied by nymphs released into an array of stems. Low vapor pressure deficit encouraged questing, while higher VPD and warmer temperature increased questing height. These results may have implications in understanding host-seeking behavior in other tick species as well.
770

Jesus Christ’s humanity in the contexts of the pre-fall and post-fall natures of humanity: a comparative and critical evaluative study of the views of Jack Sequeira, Millard J. Erickson and Norman R. Gulley

Mwale, Emanuel 12 1900 (has links)
Bibliography: leaves 653-669 / Before God created human beings, He devised a plan to save them in case they sinned. In this plan, the second Person of the Godhead would become human. Thus, the incarnation of the second Person of the Godhead was solely for the purpose of saving fallen, sinful human beings. There would have been no incarnation if human beings had not sinned. Thus, the nature of the mission that necessitated the incarnation determined what kind of human nature Jesus was to assume. It was sin that necessitated the incarnation – sin as a tendency and sin as an act of disobedience. In His incarnational life and later through His death on Calvary’s cross, Jesus needed to deal with this dual problem of sin. In order for Him to achieve this, He needed to identify Himself with the fallen humanity in such a way that He would qualify to be the substitute for the fallen humanity. In His role as fallen humanity’s substitute, He would die vicariously and at the same time have sin as a tendency rendered impotent. Jesus needed to assume a human nature that would qualify Him to be an understanding and sympathetic High Priest. He needed to assume a nature that would qualify Him to be an example in overcoming temptation and suffering. Thus, in this study, after comparing and critically evaluating the Christological views of Jack Sequeira, Millard J. Erickson and Norman R. Gulley, I propose that Jesus assumed a unique post-fall (postlapsarian) human nature. He assumed the very nature that all human beings since humankind’s fall have, with its tendency or leaning towards sin. However, unlike other human beings, who are sinners by nature and need a saviour, Jesus was not a sinner. I contend that Jesus was unique because, first and foremost, He was conceived in Mary’s womb by the power of the Holy Spirit and was filled with the Holy Spirit throughout His earthly life. Second; He was the God-Man; and third, He lived a sinless life. This study contributes to literature on Christology, and uniquely to Christological dialogue between Evangelical and Seventh-day Adventist theologians. / Philosophy, Practical and Systematic Theology / D. Phil. (Systematic Theology)

Page generated in 0.0674 seconds