Le présent travail vise à confronter les ontologies de l’imaginaire de Sartre, Merleau-Ponty et Grimaldi. Empruntant la voie d’une critique du bergsonisme, chacune de ces philosophies s’élabore en accordant une valeur ontologique au négatif et en reconsidérant la signification de la temporalité. La réflexion sur le statut de l’image, et plus avant, sur les relations entre réel et imaginaire, présent et passé, conscient et inconscient, laisse émerger un sens original de la négativité. Merleau-Ponty et Grimaldi opposent ainsi à la dialectique de l’être et du néant l’idée d’une négativité qui pénètre l’être de part en part, le premier ouvrant la voie d’une alternative phénoménologique, le second lui préférant une alternative métaphysique. Ils prétendent par là, mieux que Sartre, rendre raison de la passivité de la subjectivité, de ses attaches dans l’être, source vive du mensonge à soi-même. Les limites de l’ontologie sartrienne trouvent leur origine dans une certaine idée de la conscience qui verrouille d’emblée les relations entre imagination et affectivité. C’est au contraire le libre jeu de cet axe qui rend possible le débordement de l’horizon de visibilité de la subjectivité en direction d’un certain invisible. La jonction concrète de l’imagination et de l’affectivité se déploie alors aux parages de la notion de désir, qui donne son sens rigoureux à la négativité dépistée initialement : à la différence de Sartre, Merleau-Ponty et Grimaldi pensent le caractère médiatisant de l’être compris comme désir et théorisent un décentrement radical de la subjectivité qui culmine pour l’un dans une pensée de l’intercorporéité, pour l’autre dans une éthique du don de soi. / This study aims at confronting the ontologies of the imaginary of Sartre, Merleau-Ponty and Grimaldi. Following the path of a critical assessment of Bergsonism, each of these philosophies develops by granting ontological value to the negative, and through a reconsideration of the meaning of temporality. A new approach of negativity emerges from the reflection on the status of the image and further, upon the relationships between real and imaginary, past and present, conscious and subconscious. Merleau-Ponty and Grimaldi thus reject dialectics of being and nothingness in favour of the idea of a negativity thoroughly penetrating being itself; the first one opening the way for a phenomenological alternative, and the second favouring a metaphysical alternative. They thereby claim to account, better than Sartre does, for the passivity of subjectivity, its rootedness in being–the living source of self-deceiving.The limitations of Sartrean ontology on the subject derive from a specific view of consciousness which locks off the relation between imagination and affectivity. On the contrary, the free play of this axis allows for the overflowing of the horizon of visibility of subjectivity toward a certain invisible. The concrete junction of imagination and affectivity then spreads out into the region of the notion of desire, which gives its determinate meaning to the negativity detected in the beginning. Unlike Sartre, Merleau-Ponty and Grimaldi study the mediatizing character of being understood as desire, and they theorize about a decentring of subjectivity culminating for Merleau-Ponty in a thought of intercorporeity and for Grimaldi in an ethics of self-sacrifice.

L’être demeure encore et toujours aujourd’hui un objet extrêmement mystérieux et polémique pour les philosophes comme pour l’individu que nous sommes. Face à la réapparition perpétuelle de cet objet sous la forme d’une interrogation fondamentale, la question est celle de savoir si nous sommes face à un problème insoluble pour la raison ou bien confrontés à un problème méthodologique qu’il convient de relever. Au-delà d’une nouvelle tentative de destruction de la Métaphysique sous toutes ses formes et dans toutes ses dimensions chez les postmodernes, nous devons tenter de réfléchir aujourd’hui sur la véritable positivité du questionnement de l’être. Allant de Kant à Bachelard nous voyons alors s’ouvrir progressivement au cours de l’histoire le chemin d’une autre pratique qui peut se définir ici comme une poïétique de soi. / The “being” remains still and always today an extremely mysterious and polemic object for the philosophers as for the individual who we are. Face to the perpetual reappearance of this object in the form of a fundamental interrogation, the question is to know if we are confronted to an insoluble problem for the reason or if it is a methodological problem which it is advisable to raise. Beyond of a new attempt at destruction of Metaphysics in all its forms and its dimensions by the postmoderns, we must try to reflect today on the true positivity of the questioning of the “being”. From Kant to Bachelard, we are seeing a gradual opening during the history through the way of another practice which can be defined in that case as a self poïetic.

Dans nos pays occidentaux, les spécialistes de la question du vieillissement avancent que l'un des paradoxes du discours contemporain privilégiant d'une part, l'autonomie et d'autre part, le maintien de la dépendance des personnes âgées, s'avère fort préjudiciable à cette population.Si tous parlent d'autonomie peu évoquent la responsabilité. Pourtant, l'homme apparaît comme le sujet moral qui doit répondre de ses actions. car la véritable expérience de la responsabilité exige de réunir concrètement deux relations fondamentales: la responsabilité pour son agir propre et la responsabilité pour le monde. L'autonomie responsable des personnes âgées est donc tributaire de deux facteurs importants: la personne elle-même et la société dans laquelle elle vit. Si la résilience est une condition qui relève directement de la personne, la créativité dépend tout autant du talent personnel que des conditions dans lesquelles la société met à la disposition de la personne pour se réaliser.D'où l'intérêt grandissant vers l'éthique qui d'une part, impose une vision participative de l'autonomie c'est-à-dire une vision qui renforce le lien social et refuse l'assistance; d'autre part, le développement d'une démarche qui réalise les conditions de cette autonomie responsable en amorçant un processus d'éducation tout au long de la vie. C'est ce qu'a bien compris l'un des philosophes du vingtième siècle, Hans Jonas, qui a précisé sous le nom de principe responsabilité, une règle d'éthique à laquelle on ne saurait s'opposer.C'est donc dans cette optique que nous essayons de voir s'il est encore possible de maintenir chez les personnes âgées vivant dans nos sociétés, une autonomie responsable. / In our countries of the West, the fact that experts in the matter of aging put forth the idea that one of the paradoxes of the present debate, on the one hand, promoting the preservation of autonomy and, on the other, keeping the elderly dependent, proves to be most detrimental to this part of the population.While many speak of autonomy, few promote responsibility. Still, man appears to be, as it were, the moral subject who, must be accountable for his actions, for the true experience of responsibility requires that two fundamental relationships come together in reality: responsibility for one’s own deeds and responsibility to the world.Responsible autonomy of the elderly flows therefore from two important elements: the person and the society in which the person lives. If resilience is a condition that is a direct trait of the person, creativity depends as much on the personal talent as on the conditions which society makes available to the person to be fulfilled.Hence, the growing interest in the ethics which, on the one hand, imposes a participating vision of the autonomy, that is, a vision that reaffirms the social bond and rejects assistance: on the other hand, the development of an initiative that fulfills the conditions of this responsible autonomy by preparing a process of education all through his life. This is what one of the philosophers of the twentieth century understood so well, Hans Jonas, who stated precisely under the name of principle of responsibility, a rule of ethics which we cannot oppose. It is therefore from this point of view that we strive to see if it is still possible to maintain a responsible autonomy in the elderly persons living in our society.

Paketklassifikation ist eine Kernfunktionalität vieler Netzwerksysteme, wie zum Beispiel Firewalls und SDN-Switches. Für viele dieser Systeme ist Durchsatz von höchster Bedeutung. Weitere wichtige Eigenschaften sind dynamische Aktualisierbarkeit und hohe Regelsatz-Ausdrucksfähigkeit. Die Kombination dieser Eigenschaften macht Paketklassifikation zu einem schwierigen Problem. Diese Arbeit befasst sich mit dem Design von Klassifikationssystemen und -algorithmen, welche mindestens zwei dieser Eigenschaften vereinen. Es werden hybride Systeme sowie Systemspezialisierung verwendet, um effiziente Ansätze zum Paketklassifikationsproblem in drei Bereichen zu erarbeiten: Klassifikationsalgorithmen, Regelsatztransformation und hardwarebasierte Architekturen. Die Beiträge im Bereich der Klassifikationsalgorithmen sind Jit Vector Search (JVS) und das SFL-System. JVS verbessert existierende Techniken durch spezialisierte Suchdatenstrukturen und durch Nutzung von SIMD-Fähigkeiten der CPU, was in fast optimaler Klassifikationsperformanz bei kaum erhöhten Vorberechnungszeiten resultiert. Das hybride SFL-System hingegen kombiniert einen Klassifikationsalgorithmus mit einem Änderungspuffer, um sowohl hohe Klassifikations- als auch Aktualisierungsperformanz zu ermöglichen. Bezüglich Regelsatztransformationen wird die RuleBender-Technik vorgestellt, welche Suchbäume in Regelsätze für Firewalls mit Sprungsemantik kodiert. Somit kann der Durchsatz dieser Systeme unter Beibehaltung komplexer Regelsatzsemantik um eine Größenordnung gesteigert werden. Schließlich wird der MPFC-Ansatz vorgestellt, welcher einen Regelsatz in einen auf einem FPGA implementierbaren Matching-Schaltkreis übersetzt. Die generierten Schaltkreise sind hochoptimiert und kleiner als generische Matching-Schaltkreise. Um dynamische Regelsatzänderungen zu ermöglichen, wird der hybride Consul-Ansatz konzipiert, welcher MPFC-Matcher mit generischen Matching-Schaltkreisen kombiniert. / Packet classification is a core functionality of a wide variety of network systems, such as firewalls and SDN switches. For many of these systems, throughput is of paramount importance. Further important system traits are dynamic updateability and high expressiveness in terms of rule set semantics. The combination of several of these properties turns packet classification into a hard problem. This work focuses on the design of classification systems and algorithms that combine at least two of the abovementioned characteristics. To this end, the concepts of hybrid systems and system specialization are employed to obtain efficient approaches to the packet classification problem in three domains: classification algorithms, rule set transformation, and hardware-centric architectures. The contributions in the domain of classification algorithms are Jit Vector Search (JVS) and the SFL system. JVS improves upon existing techniques through specialized search data structures and by exploiting SIMD capabilities of the underlying CPU, which results in near-optimal classification performance at only slightly increased preprocessing times. In contrast, the SFL system is a hybrid approach that combines a classification algorithm with an update buffer to allow for high classification as well as update performance. With respect to rule set transformation, the RuleBender technique is proposed, which encodes search tree structures into rule sets of firewalls with jump semantics. That way, the throughput of these systems can be improved by an order of magnitude, while maintaining complex matching semantics. Finally, the MPFC approach is proposed, which translates a given rule set into a matching circuit that can be implemented on an FPGA. The generated circuits are highly optimized and significantly smaller than those of generic matchers. To allow for dynamic rule set updates, the hybrid Consul approach is devised, which combines MPFC circuits with a generic matcher.

In this research, it was mainly aimed to develop an acceptance model for processes, namely the process acceptance model (PAM). For this purpose, a questionnaire, comprising 3-part and 81-question, was developed to collect quantitative and qualitative data from people having relationships with certain process-focused models and/or standards (CMMI, ISO 15504, ISO 9001, ISO 27001, AQAP-160, AQAP-2110, and/or AS 9100). To revise and refine the questionnaire, expert reviews were ensured, and a pilot study was conducted with 60 usable responses. After reviews, refinements and piloting, the questionnaire was deployed to collect data and in-total 368 usable responses were collected from the people. Here, collected data were screened concerning incorrectly entered data, missing data, outliers and normality, and reliability and validity of the questionnaire were ensured. Partial least squares structural equation modeling (PLS SEM) was applied to develop the PAM. In this context, exploratory and confirmatory factor analyses were applied, and the initial model was estimated and evaluated. The initial model was modified as required by PLS SEM, and confirmatory factor analysis was repeated, and the modified final model was estimated and evaluated. Consequently, the PAM, with 18 factors and their statistically significant relationships, was developed. Furthermore, descriptive statistics and t-tests were applied to discover some interesting, meaningful, and important points to be taken into account regarding the acceptance of processes. Moreover, collected quantitative data were analyzed, and three additional factors were discovered regarding the acceptance of processes. Besides, a checklist to test and/or promote the acceptance of processes was established.

No description available.

No description available.

Η Β-χρόνια Λεμφογενής Λευχαιμία (Β-ΧΛΛ) αποτελεί τον πιο κοινό τύπο λευχαιμίας στο Δυτικό κόσμο. Η πρόγνωσή της θεωρείται ως ένα από τα πιο ενδιαφέροντα προβλήματα απόφασης στην κλινική έρευνα και πρακτική. Για διάφορους κλινικούς και εργαστηριακούς δείκτες είναι γνωστό ότι σχετίζονται με την εξέλιξη της νόσου. Για τις παραμέτρους, όμως, που εξάγονται με ανάλυση κυτταρομετρίας ροής, οι οποίες αποτελούν τον ακρογωνιαίο λίθο της διαδικασίας διάγνωσης της νόσου, το αν προσφέρουν επιπρόσθετη προγνωστική πληροφορία αποτελεί ανοιχτό πρόβλημα. Στη διατριβή αυτή προτείνουμε ένα σύστημα υποβοήθησης για τις αποφάσεις των ειδικών του πεδίου, το οποίο πραγματοποιεί πολυπαραμετρική πρόγνωση ασθενών με Β-ΧΛΛ, συνδυάζοντας τη χρήση ποικίλων ετερογενών προγνωστικών δεικτών (κλινικών, εργαστηριακών και κυτταρομετρίας ροής) που σχετίζονται με τη νόσο. Η διάγνωση της Β-ΧΛΛ βασίζεται κυρίως στη μελέτη του αντιγονικού φαινότυπου των κυττάρων των ασθενών, η οποία διενεργείται με κυτταρομετρία ροής. Αν και η διαδικασία που ακολουθείται κατά την ανάλυση αυτή είναι σαφώς ορισμένη, ο τρόπος με τον οποίο οι εργαστηριακοί υπεύθυνοι την πραγματοποιούν παραδοσιακά χαρακτηρίζεται από ανακρίβεια και υποκειμενικότητα. Καθώς η τεχνολογία της κυτταρομετρίας ροής εξελίσσεται ραγδαία, γίνεται όλο και πιο επιτακτική η ανάγκη για την ανάπτυξη αυτοματοποιημένων μεθόδων ανάλυσης των δεδομένων που παράγει. Σε αυτά τα πλαίσια, παρουσιάζουμε ένα χρήσιμο παράδειγμα αυτοματοποιημένης ανάλυσης κυτταρομετρικών δεδομένων, η οποία δεν απαιτεί την άμεση επίβλεψη των ειδικών, για τη διάγνωση ασθενών με Β-ΧΛΛ. Οι τιμές των χαρακτηριστικών παραμέτρων που εξάγονται με εφαρμογή της προτεινόμενης μεθοδολογίας, ενσωματώνονται κατόπιν στο προαναφερθέν προγνωστικό σύστημα. Ανάγοντας το πρόβλημα της πρόγνωσης της Β-ΧΛΛ σε ένα στιγμιότυπο ταξινόμησης προτύπων, καθώς και προσομοιώνοντας κάθε ένα από τα βήματα της διαδικασίας της διάγνωσης της νόσου με ένα στιγμιότυπο συσταδοποίησης δεδομένων, αντιμετωπίσαμε τα δύο προβλήματα εφαρμόζοντας τεχνικές στατιστικής μάθησης. Εστιάσαμε σε μεθοδολογίες δικτύων πεποίθησης, χρησιμοποιώντας συγκεκριμένα το naïve-Bayes μοντέλο και για τις δύο περιπτώσεις, στην επιβλεπόμενη και στη μη επιβλεπόμενη εκδοχή του, αντίστοιχα. Τα χαρακτηριστικά και η φύση των δεδομένων (κυρίως των κυτταρομετρικών) που παράγονται από έναν παθολογικό υποκείμενο μηχανισμό, όπως αυτός της νόσου, δεν ευνοούν την απευθείας εφαρμογή του παραπάνω μοντέλου στο εκάστοτε στιγμιότυπο. Για το λόγο αυτό, συνδυάσαμε την εφαρμογή του naïve-Bayes μοντέλου με κατάλληλες ευρετικές αλγοριθμικές διαδικασίες, για την επίτευξη καλύτερων αποτελεσμάτων, με κριτήριο βέλτιστου όχι μόνο κάποιες συχνά χρησιμοποιούμενες μετρικές αποτίμησης αλγόριθμων, αλλά και τη γνώμη των αιματολόγων. Χάρη στην ιδιότητά τους να ενσωματώνουν την έμπειρη γνώση των ειδικών ως εκ των προτέρων πληροφορία αρχικοποίησης των μεθόδων μάθησής τους, οι Bayesian μεθοδολογίες κρίνονται ως οι πλέον κατάλληλες για την εφαρμογή τους σε τέτοιου τύπου προβλήματα. / B-Chronic Lymphocytic Leukemia (B-CLL) is known to be the most common type of leukemia in the Western world. Its prognosis remains one of the most interesting decision problems in clinical research and practice. Various clinical and laboratory factors are known to be associated with the evolution of the disease. However, for the parameters obtained by flow cytometry analysis, that are traditionally utilized as the cornerstone during the diagnosis procedure of the disease, whether they offer additional prognostic information is an open issue. In this dissertation, we propose a decision support system to the hematologists, that provides multiparametric B-CLL patients’ prognosis, combining the usage of diverse heterogeneous factors (clinical, laboratory and flow cytometry) associated with the disease. B-CLL diagnosis is primarily derived from the study of the antigenic phenotype of the patients’ blood cells, which is held with flow cytometry analysis. Despite the fact that the method of the analysis is well defined, the process traditionally followed by the laboratory experts is characterized by amounts of inexactness and subjectivity. As flow cytometry technology advances rapidly, the need for adequate automated (computer-assisted) analysis methodologies on the data it produces is accordingly increasing. In this context, we present a useful paradigm of automated analysis of flow cytometry data, that does not require the direct supervision of the expert, for B-CLL patients’ diagnosis. The values of the flow cytometry characteristic parameters extracted by applying the proposed methodology are afterward incorporated to the prognostic system for B-CLL mentioned above. By reducing the B-CLL prognosis problem to an instance of the pattern classification problem, as well as by simulating each step of the B-CLL diagnosis procedure with an instance of the data classification problem, we proceeded with applying statistical learning techniques. We focused on Bayesian network methodologies and utilized the naïve-Bayes model for both cases, in its supervised and unsupervised version, respectively. The characteristics of the data (especially of the flow cytometry ones) generated by a pathological underlying mechanism, like the disease’s one, did not encourage the direct use of the above model. Therefore, we combined the naïve-Bayes model with a set of suitable heuristic algorithmic procedures to obtain better results, not only with respect to some commonly used algorithmic optimality metrics, but also by considering the experts’ opinion. Due to their ability of incorporating the expert knowledge as a priori initial information to their learning methods, Bayesian methodologies are considered as the most appropriate ones to make use of in such types of applications.

Les avancées de la biologie contemporaine, posent de façon nouvelle des problèmes philosophiques anciens. Ceux des rapports entre le vivant et l'inanimé, entre le corps et l'esprit, l'erreur et la vérité, sont les plus évidents. La philosophie de Spinoza, bien que datant du 17e siècle, apporte à ces problèmes des solutions plus pertinentes que la plupart des philosophies plus récentes, développées dans les siècles qui l'ont suivie. En retour, les acquis actuels des sciences physiques et biologiques, notamment des neurosciences cognitives, permettent de porter un nouveau regard sur certaines notions propres à la philosophie de Spinoza, telles que sa «petite physique», la nature cause de soi, la notion de matière, l'essence des choses, les genres de connaissance, qui acquièrent de ce fait un surcroît d'actualité. / Old philosophical problems are raised in renewed ways by advances in biology of today. Most obvious are the problems of relationship between living and non-living, mind and body, error en truth. Spinoza's philosophy, although from 17th century, offers solutions to these problems more relevant than most more recent philosophies. In return, present knowledge from physical and biological sciences, especially cognitive neurosciences, can provide a new look at some specifically Spinozist notions such as his "little physics", Nature as cause of itself, the notion of matter, the essence of a thing, kinds of knowledge, which gain all the more interest from a present day point of view.

Made available in DSpace on 2017-07-10T18:26:34Z (GMT). No. of bitstreams: 1 Juarez de Oliveira Pacheco.pdf: 950203 bytes, checksum: 1299edb78191d14fba18ef20bee6d49b (MD5) Previous issue date: 2013-02-05 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / By analyzing the concept of nihilism, which is shown polysemic in Nietzsche's work, we encounter frequent deadlocks concerning the origin of this phenomenon. This concept usually presents signifying a consequence of the moral development of the West, where the slave resentment and bad conscience, rooted in culture, ends up affecting modern man of a weariness and an emptying of value: it is nihilism in its own sense, a phenomenon of modern origin. On the other hand, there are aphorisms and excerpts, least discussed by the German philosopher in his work, indicating that the origin of nihilism refers to a distant period of human history, preceding the Christian moral-ascetic, and a phenomenon that opens a gap of absence of meaning about life and human suffering. These incompatible aspects of nihilism are present both in print, and in private notes of Nietzsche. The interior of the book Genealogy of Morals also holds that ambiguity of the concept of nihilism. The main objective of this work is to investigate the work Genealogy of Morals, with the help of other texts, trying to understand the meanings of nihilism and position in the history of civilization. Nietzsche s work as objects of study presents the concepts of resentment and bad conscience ascetic ideal, elements that are constitutive of Western morals. With interests in its topicality, Nietzsche investigates the past moral to its prehistory. Thus, this work is fundamental research into the origin of nihilism. His concepts are analyzed from a procedure that puts them in the realm of historical development and the dynamics instinctual, while concepts that change over time and have multiple meanings: with this polysemic feature that the central elements of the work are presented as well as nihilism. The Genealogy of Morals finally reveals that nihilism has various meanings, but that does not necessarily clash with each other. We show in this work a form of nihilism primordial, a "first nihilism" that is precedent-Christian ascetic morality, including that operates as one of the causes of this moral. However, nihilism is presented as historical product of peacemaking mechanisms of civilization, which inevitably leads to poor awareness and resentment. Human instincts turn inward, causing a great malaise of civilization in the form of a long suffering baseless. The ascetic priest gives an answer to this suffering, reverses the direction of resentment, bad conscience reinterpreting the animal, making it more serious, in a way defined as the interpretation of suffering for sin. The bad conscience made man suffer senseless with instincts that turned against him, however, with the ascetic interpretation, now he unloads his forces against them with a sense that justifies the suffering. / Ao analisar o conceito de niilismo, que se mostra polissêmico na obra de Nietzsche, nos deparamos com impasses frequentes referentes à origem desse fenômeno. Esse conceito se apresenta geralmente significando uma consequência do desenvolvimento da moral do ocidente, em que o ressentimento escravo e a má consciência, enraizados na cultura, se transformam até que terminam acometendo o homem moderno de um cansaço e de um esvaziamento de valor: é o niilismo em seu sentido mais próprio, um fenômeno de origem moderna. Por outro lado, há aforismos e trechos, menos debatidos pelo filósofo alemão em sua obra, que indicam que a origem do niilismo remete a um período longínquo da história humana, precedente à moral ascético-cristã, e a um fenômeno que abre uma lacuna de ausência de sentido em relação à vida e ao sofrimento humano. Esses aspectos incompatíveis do niilismo se apresentam tanto em textos publicados, quanto em anotações privadas de Nietzsche. O interior da obra Genealogia da moral também detém essa ambiguidade do conceito de niilismo. O objetivo principal desse trabalho é investigar a obra Genealogia da moral, com a ajuda de outros textos, buscando compreender os significados e a posição do niilismo na história da civilização. O escrito nietzschiano apresenta como objetos de estudo os conceitos de ressentimento, má consciência e ideal ascético, elementos que são constitutivos da moral ocidental. Com interesses na sua atualidade, Nietzsche investiga o passado moral até a sua pré-história. Com isso, essa obra é fundamental na investigação sobre a origem do niilismo. Seus conceitos são analisados a partir de um procedimento que os coloca sob a esfera do devir histórico e da dinâmica instintual, enquanto conceitos que se transformam ao longo do tempo e possuem múltiplos sentidos: é com essa característica polissêmica que os elementos centrais da obra se apresentam, assim como o niilismo. A Genealogia da moral revela finalmente que o niilismo possui sentidos variados, mas que não necessariamente se chocam entre si. Evidenciamos nessa obra uma forma de niilismo primordial, um niilismo primeiro , que é precedente à moral ascético-cristã, que opera inclusive como uma das causas dessa moral. Entretanto, o niilismo se apresenta como histórico, produto dos mecanismos de pacificação da civilização, que inevitavelmente levam à má consciência e ao ressentimento. Os instintos humanos se voltam para dentro, causando um grande mal estar civilizatório, sob a forma de um sofrimento por longo tempo sem fundamento. O sacerdote ascético dá uma resposta a esse sofrimento, inverte a direção do ressentimento, reinterpretando a má consciência animal, tornando-a mais grave, de uma forma definida, como a interpretação do sofrimento pelo pecado. A má consciência fazia o homem sofrer sem sentido com os instintos que se voltavam contra si, porém, com a interpretação ascética, ele agora descarrega suas forças contra si com um sentido que justifica o sofrimento.