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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
641

Estudo das interleucinas no processo inflamatório na doença pulmonar obstrutiva crônica, Prednisona/uso terapêutico, / -

Denise Moreira de Andrade Cotrim 14 September 2004 (has links)
Embora a utilização do corticóide oral não seja indicada no tratamento de manutenção na doença pulmonar obstrutiva crônica, identificamos em nosso ambulatório, um grupo de pacientes que fazem uso desta medicação de forma continuada e, nos quais, todas as tentativas anteriores de retirada da medicação, havia resultado em exacerbação dos sintomas. O objetivo deste estudo foi o de analisar os fenômenos inflamatórios associados à tentativa de redução progressiva do corticóide oral nesses doentes. Avaliamos o escarro induzido de 14 pacientes usuários crônicos de corticóide. Após a avaliação basal, realizada enquanto os pacientes faziam uso de sua dose habitual da medicação (V0), procedemos ao aumento da prednisona a 40 mg por dia, por duas semanas (V1). A seguir, reduzimos progressivamente a dose até que ocorresse uma exacerbação (EXAC), quando a dose de 40 mg de prednisona foi re-introduzida por duas semanas (APÓS). Comparamos os resultados deste grupo aos de um grupo de pacientes portadores de DPOC não-usuários de corticóide oral. Esses pacientes foram avaliados na condição basal (V0), quando exacerbaram (EXAC) e após o tratamento com 40 mg de prednisona, por duas semanas (APÓS). As variáveis analisadas no escarro foram: % de neutrófilos, % de eosinófilos, % de macrófagos, número total de células, interleucinas 4, 6 e 8. Constatamos que o grupo corticóide apresentou um aumento significativo na porcentagem de eosinófilos na exacerbação em relação a V0, e uma redução significativa em APÓS, em relação a EXAC. Isto não ocorreu no grupo não-corticóide. Ao compararmos os dois grupos, observamos que a concentração das interleucinas 4, 6 e 8, foi significativamente mais alta no grupo corticóide em V0 e na exacerbação em relação ao grupo não-corticóide. Quando analisamos o comportamento das interleucinas nas avaliações seqüenciais, dentro de cada grupo, observamos que a interleucina 4 tendeu à elevação na exacerbação, no grupo corticóide, sem atingir, entretanto, significância estatística. As interleucinas 6 e 8 aumentaram significativamente no grupo corticóide na visita APÓS. Concluímos que a retirada progressiva de corticóide oral induz a exacerbação em pacientes com DPOC corticóide-dependentes com um processo inflamatório eosinofílico, que tende à reversão após o aumento da dose do corticóide / Although in chronic obstructive lung disease the use of oral corticoid is not indicated in the maintenance treatment, we identified a group of patients that make use of this medication continuously. The objective of this study was to analyze the inflammatory phenomena associated to the attempt of progressive reduction of oral corticoids in these patients. We evaluated induced sputum of 14 patients on long-term use of oral corticoids. After the basal evaluation, accomplished while the patients made use of their habitual dose of the medication (V0), we increased the dose of prednisone to 40 mg daily for two weeks (V1). To proceed we reduced the dose progressively until an exacerbation occurred (EXAC), when the dose of prednisone 40 mg daily was reintroduced for two weeks (AFTER). We compared the results to a group of patients with COPD not on use of oral corticoids, that were appraised in the basal condition (V0), when they exacerbated (EXAC) and after the treatment with prednisone 40 mg daily for two weeks (AFTER). The variables analyzed in the sputum were:, % of neutrophils, % of eosinophils, % of macrophages, total number of cells, interleukins 4, 6 and 8. We verified that the corticoid group presented a significant increase in the percentage of eosinophils at the exacerbation in relation to V0, and a significant reduction in AFTER in relation to EXAC. This didn\'t happen in the non corticoid group. When we compared the two groups we observed that the concentration of the interleukins was significantly higher in corticoid group in V0 and at the exacerbation in relation to the non corticoid group. When we analyzed the behavior of the interleukins along the evaluations in each group we observed that interleukin 4 tended to an elevation at the exacerbation in the corticoid group, without reaching statistical significance. Interleukins 6 and 8 increased significantly in the corticoid group in the visit AFTER. We concluded that the progressive reduction of oral corticoid induces exacerbation in patients with COPD on long-term use of prednisone with an eosinophilic inflammatory process that tends to reverse after the increase of the dose of the corticoid
642

L’expérience de parents d’adolescents ayant un trouble du spectre de l’autisme avec un handicap intellectuel à la suite d’une hospitalisation en pédopsychiatrie

Cuillerier, Laurence 04 1900 (has links)
No description available.
643

Work-related rehabilitation for strengthening working careers:a multiperspective and mixed methods study of its mechanisms

Juvonen-Posti, P. (Pirjo) 29 May 2018 (has links)
Abstract Coping at work and job retention have been on the list of priorities of European countries for some decades. Vocational rehabilitation is a key measure for preventing work disability, but its possibilities have remained unused in many respects. Moreover, rehabilitation tasks are defined differently depending on the perspective taken. The purpose of this thesis is to determine the possibilities that arise from defining work-related rehabilitation tasks in a way that combines different perspectives and interests. The research questions are: 1) What were the impacts on working career and psychosocial factors of an intervention for long-term unemployed people with disabilities? 2) What kind of processes and mechanisms promoted the working careers and other outcomes of the employed people during the interventions? 3) What forms of collaboration took place between the rehabilitees and different stakeholders, and to what extent did the rehabilitees have opportunities to choose and act during the process? The empirical data for the study were collected from two vocational rehabilitation research projects. The research design was a multiple case study from multiple perspectives combined with mixed methods. The materials were collected through surveys, individual and group interviews, documents, and register follow-up. We found the contextual mechanism through which the outcomes of the work-related rehabilitation emerged. The process was promoted or hindered by actions taken by all stakeholders. The promoting or hindering mechanisms were born through the actions taken by the supervisor in particular, the occupational health service and rehabilitation service provider, and the individual’s life situation factors. Similar factors promoted and hindered the re-employment and staying or returning to work outcomes. Enhancing the rehabilitees’ own agency is also important, regardless of how weak it is at the beginning. I also present a new way of assigning rehabilitation tasks, which structures the complexity of the field of work-related rehabilitation and helps manage it. Work-related rehabilitation is a combination of societal and individual actions. The results of this study will help all actors involved in rehabilitation to improve the outcomes of work-related rehabilitation by developing opportunities for the rehabilitees’ own agency and collaboration / Tiivistelmä Työurien jatkaminen on keskeinen eurooppalaisten yhteiskuntien selviämisen haaste. Kuntoutus on riittämättömästi hyödynnetty resurssi työurien pidentämiseksi. Lisäksi kuntoutuksen tehtävät määrittyvät eri näkökulmista eri tavalla. Tutkimuksen tavoitteena on tarkastella, miten työikäisten kuntoutuksen tehtävää voitaisiin määritellä eri toimijoiden intressejä ja päämääriä yhdistäen. Tutkimuskysymyksiä oli kolme: 1) Mitkä olivat monimuotoisen ammatillisen kuntoutuksen vaikutukset pitkäaikaistyöttömien työuraan ja muihin psykososiaalisiin tekijöihin? 2) Millaiset prosessit ja mekanismit edistivät työuria työllisten monimuotoisen ammatillisen kuntoutuksen interventiossa? 3) Minkälaisia yhteistyömuotoja työhön kytkeytyvässä kuntoutuksessa kuntoutujan ja eri toimijoiden välillä toteutui, ja missä määrin kuntoutujat pystyivät vaikuttamaan omiin valinta- ja toimintamahdollisuuksiinsa prosessin aikana? Aineisto koostui kahden ammatillisen kuntoutuksen kehittämishankkeen arviointitutkimusaineistoista. Tutkimusasetelma oli monitapaustutkimus, joka oli toteutettu moninäkökulmaisena mixed method –tutkimuksena. Aineistot oli koottu kyselyiden, yksilö- ja ryhmähaastatteluiden, dokumenttien ja rekisteriseurannan avulla. Aineistojen analyysejä oli tehty aineistokokonaisuuksittain analysoiden kvantitatiiviset ja kvalitatiiviset aineistot erikseen sekä yhdistämällä aineistoja tapaustutkimuksen keinoin. Tutkimuksessa löytyi mekanismi, jonka kautta kuntoutuksen tulokset syntyivät tai jäivät syntymättä. Edistävät ja estävät mekanismit liittyivät erityisesti esimiehen, työterveyshuollon ja kuntoutuksen palvelutuottajan toimintaan ja kuntoutujan elämäntilanteeseen. Samanlaiset tekijät edistivät ja estivät työttömillä ja työllisillä kuntoutumista. Lisäksi työhön kytkeytyvässä kuntoutuksessa kuntoutujan oman toimijuuden tukeminen on tärkeää, vaikka se alkuvaiheessa olisi vähäinen. Tutkimuksessa kuvataan työikäisten kuntoutuksen tehtävät uuden mallin avulla. Tämä jäsentää ammatillisen kuntoutuksen kentän kompleksisuutta ja auttaa hallitsemaan sitä. Työhön kytkeytyvä kuntoutus muodostuu yhteiskuntaan ja yksilöön kohdistuvista toimista, joilla mahdollistetaan työelämään paluu ja osallistuminen. Tulosten avulla kuntoutuksen toteuttajat, tutkijat ja viranomaiset voivat parantaa kuntoutuksen työuravaikutuksia kehittämällä kuntoutujan osallistumismahdollisuuksia ja yhteistoimintaa.
644

Análise dos resultados imediatos e tardios do tratamento percutâneo da coartação da aorta em adolescentes e adultos: comparação entre balões e stents / Analysis of the immediate and late results of percutaneous treatment of coarctation of the aorta in adolescents and adults: comparison between balloons and stents

Pedra, Carlos Augusto Cardoso 05 July 2004 (has links)
Mais informações são necessárias para definir se o tratamento percutâneo da coartação da aorta com stents é superior à angioplastia com cateter-balão. De julho de 2000 a maio de 2003, 21 adolescentes e adultos com coartação da aorta focal e média de idade de 24 anos (DP 11 anos) foram submetidos, consecutivamente, a implante de stents (grupo 1). Os resultados foram comparados com os obtidos em um grupo histórico de 15 pacientes com média de idade de 18 anos (DP 10 anos) (p = 0,103) submetidos a angioplastia (grupo 2) nos últimos 18 anos. Após o procedimento, a redução do gradiente sistólico foi maior (99% [DP 2%] versus 87% [DP 17%]; p = 0,015), o gradiente residual foi menor (0,4 mmHg [DP 1,4 mmHg] versus 5,9 mmHg [DP 7,9 mmHg]; p = 0,019), o ganho no local da coartação foi maior (333% [DP 172%] \"versus\" 190% [DP 104%]; p = 0,007) e o diâmetro da coartação foi maior (16,9 mm [DP 2,9 mm] versus 12,9 mm [DP 3,2 mm]; p < 0,001) no grupo 1. Alterações da parede da aorta, incluindo dissecções, abaulamentos e aneurismas, foram observadas em oito pacientes do grupo 2 (53%) e em um do grupo 1 (7%) (p < 0,001). Não houve complicações maiores. Cateterismo (n = 33) ou ressonância magnética (n = 2) de controle foram realizados em seguimento mediano de um ano para o grupo 1 e um ano e meio para o grupo 2 (p = 0,005). A redução do gradiente sistólico persistiu em ambos os grupos; entretanto, gradientes tardios mais altos foram observados no grupo 2 (mediana de 0 mmHg para o grupo 1 versus 3 mmHg para o grupo 2; p = 0,014). Não houve perdas no diâmetro da coartação no grupo 1 e houve ganho tardio no grupo 2 (16,7 mm [DP 2,9 mm] versus 14,6 mm [DP 3,9 mm]; p = 0,075). No grupo 1, dois pacientes necessitaram de novo implante de stent em decorrência da formação de aneurisma ou fratura da malha do stent. No grupo 2, as anormalidades da parede aórtica não progrediram e um paciente necessitou de redilatação em decorrência da recoartação. A pressão arterial sistêmica foi semelhante em ambos os grupos durante o seguimento (sistólica: 126 mmHg [DP 12 mmHg] no grupo 1 versus 120 mmHg [DP 15 mmHg] no grupo 2; diastólica: 81 mmHg [DP 11 mmHg] no grupo 1 versus 80 mmHg [DP 10 mmHg] no grupo 2; p = 0,149 e p = 0,975, respectivamente). Apesar de os desfechos clínicos terem sido satisfatórios e similares com ambas as técnicas, o uso de stents propiciou resultados mais previsíveis e uniformes para alívio da estenose, minimizando também o risco de desenvolvimento de alterações da parede da aorta. / More information is needed to define whether stenting is superior to balloon angioplasty for coarctation of the aorta. From July/2000 to May/2003, 21 adolescents and adults with discrete coarctation underwent consecutive stent implantation at a mean age of 24 years (SD 11 years) (group 1). The results were compared to those achieved by balloon angioplasty performed in the last 18 years in a historical group of 15 patients at a mean age of 18 years (SD 10 years) (p = 0.103) (group 2). After the procedure, systolic gradient reduction was higher (99% [SD 2%] vs. 87% [SD 17%]; p = 0.015), residual gradients lower (0.4 mmHg [SD 1.4 mmHg] vs. 5.9 mmHg [SD 7.9 mmHg); p = 0.019), gain at the coarctation site higher (333% [SD 172%] vs. 190% [SD 104%]; p = 0.007) and coarctation diameter larger (16.9 mm [SD 2.9 mm] vs.12.9 mm [SD 3.2 mm]; p < 0.001) in group 1. Aortic wall abnormalities, including dissections, bulges and aneurysms, were observed in eight patients in group 2 (53%) and in one in group 1 (7%) (p < 0.001). There was no major complication. Repeat catheterization (n = 33) or magnetic resonance imaging (n = 2) was performed at a median follow-up of 1.0 year for group 1 and 1.5 year for group 2 (p = 0.005). Gradient reduction persisted in both groups, although higher late gradients were observed in group 2 (median of 0 mmHg for group 1 vs. 3 mmHg for group 2; p = 0.014). There was no late loss in the coarctation diameter in group 1 and there was a late gain in group 2 (16.7 mm [SD 2.9 mm] for group 1 vs. 14.6 mm [SD 3.9 mm] for group 2; p = 0.075). Two patients required late stenting due to aneurysm formation or stent fracture in group 1. Aortic wall abnormalities did not progress and one patient required redilation due to recoarctation in group 2. Blood pressure was similar in both groups at follow-up (systolic: 126 mmHg [SD 12 mmHg] in group 1 vs. 120 mmHg [SD 15 mmHg] in group 2; diastolic: 81 mmHg [SD 11 mmHg] in group 1 vs. 80 mmHg [SD 10 mmHg] in group 2; p = 0.149 and p = 0.975, respectively). Although satisfactory and similar clinical outcomes were observed with both techniques, the use of stents yielded more predictable and uniform results for stenosis relief, also minimizing the risk of developing aortic wall abnormalities.
645

"Avaliação de pacientes assintomáticos com formas cardíacas iniciais da doença de Chagas, através da análise do eletrocardiograma dinâmico, ecocardiograma e peptídeo natriurético tipo B" / Evaluation of asymptomatic patients with initial cardiac forms of Chagas' disease through the analysis of dynamic electrocardiography, echocardiography and Type-B natriuretic peptides

Marques, Divina Seila de Oliveira 08 October 2004 (has links)
Para avaliar as características clínicas e evolutivas em pacientes com formas cardíacas iniciais assintomáticas da doença de Chagas, realizou-se estudo prospectivo em 108 pacientes com idade entre 18 e 50 anos, atendidos entre abril e novembro de 2002 no ambulatório de doença de Chagas da Universidade Estadual de Londrina. Os pacientes foram submetidos a 1)avaliação clínica, 2)eletrocardiograma (ECG), 3)radiografia de tórax e cálculo do índice cardio-torácico (ICT), 4)eletrocardiografia dinâmica de 24 horas, 5)ecocardiografia bidimensional com Doppler tecidual e 6)dosagem plasmática do peptídeo natriurético tipo B (BNP). Os pacientes foram divididos em 3 grupos: 50 no GI - ECG e ICT normais, 31 no GIIA - ECG com alterações características de doença de Chagas e 25 no GIIB - ECG com alterações não características de doença de Chagas / To evaluate clinical and evolutive features in patients with initial asymptomatic cardiac Chagas' disease, a prospective study was carried out with 108 patients, age 18 and 50, at the Londrina State University Chagas' disease outpatient clinic, from April to November 2002. Patients were submitted to: 1) clinical evaluation, 2) electrocardiography (EKG), 3) chest radiography and cardiothoracic index (CTI), 4)24-hour dynamic electrocardiography, 5) bi-dimensional echocardiography with tissued Doppler imaging and 6) type-B natriuretic peptide (BNP) plasmatic dosage. Patients were divided into 3 groups: GI - normal EKG and CTI (50 patients), GIIA - EKG with typical Chagas' disease alterations (31 patients) and GIIB - EKG with alterations not characteristic of Chagas´ disease (25 patients)
646

Statistiques appliquées en chirurgie cardiaque adulte : analyses de survie et applications du “propensity score”

Stevens, Louis-Mathieu 05 1900 (has links)
L'objectif principal de ce travail est d’étudier en profondeur certaines techniques biostatistiques avancées en recherche évaluative en chirurgie cardiaque adulte. Les études ont été conçues pour intégrer les concepts d'analyse de survie, analyse de régression avec “propensity score”, et analyse de coûts. Le premier manuscrit évalue la survie après la réparation chirurgicale de la dissection aigüe de l’aorte ascendante. Les analyses statistiques utilisées comprennent : analyses de survie avec régression paramétrique des phases de risque et d'autres méthodes paramétriques (exponentielle, Weibull), semi-paramétriques (Cox) ou non-paramétriques (Kaplan-Meier) ; survie comparée à une cohorte appariée pour l’âge, le sexe et la race utilisant des tables de statistiques de survie gouvernementales ; modèles de régression avec “bootstrapping” et “multinomial logit model”. L'étude a démontrée que la survie s'est améliorée sur 25 ans en lien avec des changements dans les techniques chirurgicales et d’imagerie diagnostique. Le second manuscrit est axé sur les résultats des pontages coronariens isolés chez des patients ayant des antécédents d'intervention coronarienne percutanée. Les analyses statistiques utilisées comprennent : modèles de régression avec “propensity score” ; algorithme complexe d'appariement (1:3) ; analyses statistiques appropriées pour les groupes appariés (différences standardisées, “generalized estimating equations”, modèle de Cox stratifié). L'étude a démontrée que l’intervention coronarienne percutanée subie 14 jours ou plus avant la chirurgie de pontages coronariens n'est pas associée à des résultats négatifs à court ou long terme. Le troisième manuscrit évalue les conséquences financières et les changements démographiques survenant pour un centre hospitalier universitaire suite à la mise en place d'un programme de chirurgie cardiaque satellite. Les analyses statistiques utilisées comprennent : modèles de régression multivariée “two-way” ANOVA (logistique, linéaire ou ordinale) ; “propensity score” ; analyses de coûts avec modèles paramétriques Log-Normal. Des modèles d’analyse de « survie » ont également été explorés, utilisant les «coûts» au lieu du « temps » comme variable dépendante, et ont menés à des conclusions similaires. L'étude a démontrée que, après la mise en place du programme satellite, moins de patients de faible complexité étaient référés de la région du programme satellite au centre hospitalier universitaire, avec une augmentation de la charge de travail infirmier et des coûts. / The main objective of this work is to study in depth advanced biostatistical techniques in adult cardiac surgery outcome research. The studies were designed to incorporate the concepts of survival analysis, regression analysis with propensity score, and cost analysis. The first manuscript assessed survival, and cardiovascular specific mortality, following surgical repair of acute ascending aortic dissection. The statistical analyses included survival analyses with multiphase parametric hazard regression and other parametric (exponential, Weibull), semi-parametric (Cox) or non-parametric models (Kaplan Meier), comparison with the survival of a matched cohort for age, gender and race using State lifetables, and modelization with bootstrapping and multinomial logit models. The study showed that the early and late survival following surgical repair has improved progressively over 25 years in association with noticeable changes in surgical techniques and preoperative diagnostic testing. The second manuscript focused on outcomes following isolated coronary artery bypass grafting in patients with a history of percutaneous coronary intervention. The statistical analyses included multivariable regression models with propensity score, complex matching algorithm (1:3) and appropriate statistical analyses for matched groups (standardized differences, generalized estimating equations, and survival analyses with stratified proportional hazards models). The study showed that remote prior percutaneous coronary intervention more than 14 days before coronary artery bypass grafting surgery was not associated with adverse outcomes at short or long-term follow-up. The third manuscript evaluated the financial consequences and the changes in case mix that occurred at an academic medical center subsequent to the implementation of a satellite cardiac surgery program. The statistical analyses included two-way ANOVA multivariable regression models (logistic, linear or ordinal), propensity score, and cost analyses using Log-Normal parametric models. “Survival” analyses models were also explored, using “cost” instead of “time” as the outcome of interest, and led to similar conclusions. The study showed that, after implementation of the satellite cardiac surgery program, fewer patients of lower complexity came to the academic medical center from the satellite program area, with a significant increase in nursing workload and costs.
647

Cinq ans après : trajectoire de consommation et processus de changement dans un échantillon présentant une comorbidité psychiatrique

Acier, Didier January 2008 (has links)
Thèse numérisée par la Division de la gestion de documents et des archives de l'Université de Montréal
648

Short-term effects of controlled conservation burning

Rindzevičius, Vytautas January 2014 (has links)
In this study, the immediate and short term (three months) effects of conservation burning have been investigated in coniferous forests in southeastern Sweden. Five tree species were investigated Picea abies (Norway spruce), Pinus sylvestris (Scots pine), Populus tremula (aspen), Betula pendula (silver birch) and Betula pubescens (downy birch), as well as ground vegetation of mosses, dwarf shrubs and ground lichens. Burning increased the proportion of live deciduous tree shoots from 51 % to 81 % and the live tree shoot size distribution of four tree species was significantly changed by fire. Fire affected the tree species differently. Three months after burning deciduous tree species exhibited strong sprouting, while P. sylvestris had established many seedlings, significantly increasing its share of the tree stand. P. abies lacked any visible positive response to burning and its number of live shoots decreased by 83 %. Mineral soil was exposed on only the moss vegetation and covered just 4 % of the studied plot area. The initial vegetation response to fire was negative, but significant dwarf shrub recovery was detected three months after burning.
649

Osteochondrale Transplantation am Kniegelenk – Schicksal der Entnahmedefekte nach Implantation von TruFit®-Zylindern bei großen Knorpeldefekten / Osteochondral transplantation in the knee joint - fate of donor sites after implantation of TruFit Plugs

Quarch, Verena Mafalda Antonia 01 July 2014 (has links)
Aufgrund einer möglichen Entnahmemorbidität sind Knorpelschäden am Knie von mehr als 3 cm ² Größe bei der autologen osteochondralen Transplantation (OCT) als kritisch zu betrachten. In dieser Studie wurde untersucht, ob die Entnahmemorbidität beo großen Knorpelschädendurch durch den Einsatz von OBI TruFit Plugs reduziert werden kann. Wir führten die autologe osteochondrale Transplantation bei insgesamt 37 Patienten durch und die Knorpel-Knochen-Zylinder wurden aus dem dorsalen medialen femoralen Kondylus entfernt. Die Defekte an der Entnahmestelle wurde bei 21 Patienten (mit einer durchschnittlichen Defektgröße von 5,5 cm²) mit künstlichen TruFit Plugs gefüllt, bei 16 Patienten (mit einer durchschnittlichen Defektgröße von 4,6 cm2) wurden die Defekte der Entnahmestellen unbehandelt gelassen. Im Durchschnitt wurden die Patienten in der Studiengruppe (mit TruFit Plugs behandelt) nach 12,8 (± 1,8) Monaten postoperativ und nach 25,2 (± 1,8) Monate erneut nachuntersucht; in der Kontrollgruppe (unbehandelt gelassene Entnahmestellen) wurden dieNachuntersuchungen nach 13,8 (± 4,3) Monate durchgeführt sowie nach 58,9 (± 4,0) Monaten. In der Studiengruppe verbesserten sich die Ergebnisse von Tegner-Score, WOMAC, VAS und Knee-Society-Score von präoperativ 3,2 (± 0,8), 60,9 (± 41,6), 133,6 (± 27,1) und 4,8 (± 2,3) auf 3,9 (± 0,6), 35,5 ( ± 27,1), 177,8 (± 16,6) und 3,3 (± 2,9) Punkten zum Zeitpunkt des zweiten Follow-up; die Kontrollgruppe zeigte präoperativ Score-Ergebnisse von 2,8 (± 0,9), 73,3 (± 50,2), 123,8 (± 41,5 ) und 5,3 (± 2,7) Punkten und verbesserte diese auf 3,6 (± 0,8), 41,4 (± 28,8), 179,3 (± 17,5) und 3,1 (± 2,0) Punkte zum Zeitpunkt des zweiten Follow-up. Je kleiner der anfängliche Knorpeldefekt in der Studiengruppe war, desto besser wurden die WOMAC Score-Werte (p < 0,05). Die MRI-Auswertung führte zu einer Verbesserung der Gesamtpunktzahl im modifizierten Henderson in der Studiengruppe an den Entnahmestellen von 19,2 (± 3,3) auf 13,7 (± 2,1) Punkte und an der Empfängerstelle von 12,2 (± 2,4) auf 12 (± 1,7) Punkte (p <0,001), die Score-Werte für die die Kontrollgruppe zeigte an den Entnahmestellen 18,3 (± 3,4) und 15,4 (± 4,4) Punkte sowie für die Empfängerstellen 11,1 (± 1,8) und 13,7 (± 2,6) Punkte (p = 0,0015). OCT ist eine wirksame Therapie auch bei großen Knorpeldefekten> 3 cm ². Die Rückenflosse medialen Femurkondylus ist ein geeigneter Spender Website, zeigt eine niedrige Entnahmemorbidität und eine hohe Regenerationsfähigkeit. Durch das Ausfüllen der Mängel mit TruFit Implantate keine klinischen Verbesserungen gefunden als Entnahmemorbidität bereits niedrig ist sowieso. Allerdings nahm die Regeneration von Defekten mit TruFit Implantate gefüllt mehr als 2 Jahren.
650

Accompagnement de l'élève de 16 à 24 ans en formation générale des adultes du Québec et réussite au sein de l'école

Lethiecq, Monique 04 1900 (has links)
Afin d’enrichir les outils en matière de solution au décrochage scolaire, cette recherche s’intéresse à l’accompagnement de l’élève et à la réussite au sein de l’école. Elle se déroule dans le cadre de la formation générale des adultes (FGA) âgés de 16 à 24 ans et fréquentant les centres d’éducation des adultes du Québec (CÉA). L’objectif général est de décrire ce qui se fait comme pratiques d’accompagnement de l’élève pour la réussite tout en identifiant les caractéristiques et les objectifs de ces pratiques. Pour ce faire, trois questions de recherche ont été étudiées à savoir : 1) que se fait-il comme pratiques d’accompagnement en FGA, 2) quels sont les objectifs poursuivis par ces pratiques et, enfin, 3) quelles sont les caractéristiques de ces pratiques? Cette étude s’appuie sur l’approche de la sociologie de l'éducation de François Dubet (1994) et propose d’examiner trois dimensions (pédagogique, personnelle et sociale) et sept formes de pratiques d’accompagnement de l’élève : le tutorat, le counseling, le compagnonnage, l’entraide par les pairs, le mentorat, le cybermentorat et les pratiques pédagogiques des enseignants. La démarche étant d’établir un ensemble de pratiques d’accompagnement de l’élève comme il se présente dans le milieu, puisque toutes les pratiques d'accompagnement n’avaient pas été, avant notre recherche, répertoriées en tant que telles. Les résultats obtenus permettent de constater la présence d’un déploiement important de plusieurs pratiques d’accompagnement de l’élève en FGA incluant les pratiques pédagogiques des enseignants. En effet, le tutorat et le counseling sont deux pratiques qui obtiennent des scores importants. De plus, il aura été possible de documenter de façon assez complète les pratiques pédagogiques des enseignantes dites « d’accompagnement de l’élève » et de comprendre l’articulation de l’ensemble de ces pratiques avec la réussite de l’élève au sein de l’école. Au terme de cette recherche, deux sources de connaissances ont été mises en évidence. D’abord, la première découle des composantes issues du modèle théorique à l’étude, ensuite, la deuxième concerne l’explicitation des pratiques pédagogiques des enseignants. Dans les deux cas, les résultats, ainsi que les analyses, révèlent le caractère central de la dimension pédagogique dans l’accompagnement de l’élève en FGA, ce qui nous renvoie à l’importante contribution, en matière d’accompagnement de l’élève en FGA, de l’enseignant, puisque ce dernier inclut l’accompagnement de l’élève dans l’acte même d’enseigner. / With a view to developing and refining the tools needed to better solve the problem of school drop-out rates, this research interests itself in the accompaniment of the student and the resulting success in the school. It is addressed to the 16 to 24 year old students that are attending Québec’s FGA Education Centres. The general objective is describing what practices are used to accompany the student toward success while also identifying and describing the characteristics and objectives of said practices. In order to achieve this goal, three research questions have been studied, namely: 1) what are the accompaniment methods used in FGA; 2) what are the objectives sought with the use of these methods, and; 3) what are the characteristics of these methods? This research leans on the approach of sociology of education developed by François Dubet (1994), and proposes to examine three dimensions (pedagogical, personal, and social) as well as seven methods of student accompaniment: tutoring, counselling, pair work, assistance between peers, mentoring, cyber-mentoring, and teacher pedagogical methods. The undertaking is aimed at establishing a group of accompaniment practices for the student in his environment. All of these practices, prior to our research, had never been tabulated. The results obtained permit us to observe an important deployment of several accompaniment methods in use in FGA, including the teachers’ own pedagogical methods. In fact, tutoring and counselling are two methods that score high marks. In addition, this research has helped make it possible to document in a rather complete manner the teachers’ pedagogical methods in said student accompaniment, and to understand the dynamics of these methods in student successes at school. Upon the completion of this research, two sources of knowledge stand out. The first one emanates from the components of the theoretical model presently being studied, while the second relates to the specificity of the teachers’ pedagogical methods. In both cases the results, as well as the analyses, reveal the importance of the pedagogical dimension with respect to accompanying the FGA student, which in turn leads us back to the important contribution made by the teacher in student accompaniment in FGA, as in fact the teacher includes student accompaniment in the actual practice of teaching.

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