The quality of automatic speech recognition has increased dramatically the last few years, but the performance for low and middle resource languages such as Swedish is still far from optimal. In this project a language model trained on large written corpora called KB-BERT is utilized to improve the quality of transcriptions for Swedish. The large language model is inserted as a repairing module after the automatic speech recognition, aiming to repair the original output into a transcription more closely resembling the ground truth by using a sequence to sequence translating approach. Two automatic speech recognition models are used to transcribe the speech, one of the models are developed in this project using the Kaldi framework, the other model is Microsoft’s Azure Speech to text platform. The performance of the translator is evaluated with four different datasets, three consisting of read speech and one of spontaneous speech. The spontaneous speech and one of the read datasets include both native and non-native speakers. The performance is measured by three different metrics, word error rate, a weighted word error rate and a semantic similarity. The repairs improve the transcriptions of two of the read speech datasets significantly, decreasing the word error rate from 13.69% to 3.05% and from 36.23% to 21.17%. The repairs improve the word error rate from 44.38% to 44.06% on the data with spontaneous speech, and fail on the last read dataset, instead increasing the word error rate. The lower performance on the latter is likely due to lack of data. / Automatisk taligenkänning har förbättrats de senaste åren, men för små språk såsom svenska är prestandan fortfarande långt ifrån optimal. Det här projektet använder KB-BERT, en neural språkmodell tränad på stora mängder skriven text, för att förbättra kvalitén på transkriptioner av svenskt tal. Transkriptionerna kommer från två olika taligenkänningsmodeller, dels en utvecklad i det här projektet med hjälp av mjukvarubiblioteket Kaldi, dels Microsoft Azures plattform för tal till text. Transkriptionerna repareras med hjälp av en sequence-to-sequence översättningsmodell, och KB-BERT används för att initiera modellen. Översättningen sker från den urpsrungliga transkriptionen från en av tal-till-text-modellerna till en transkription som är mer lik den korrekta, faktiska transkriptionen. Kvalitéen på reparationerna evalueras med tre olika metriker, på fyra olika dataset. Tre av dataseten är läst tal och det fjärde spontant, och det spontana talet samt ett av de lästa dataseten kommer både från talare som har svenska som modersmål, och talare som har det som andraspråk. De tre metrikerna är word error rate, en viktad word error rate, samt ett mått på semantisk likhet. Reparationerna förbättrar transkriptionerna från två av de lästa dataseten markant, och sänker word error rate från 13.69% till 3.05% och från 36.23% till 21.17%. På det spontana talet sänks word error rate från 44.38% till 44.06%. Reparationerna misslyckas på det fjärde datasetet, troligen på grund av dess lilla storlek.

Denna studie syftar till att undersöka hur ultraljudsutbildningar för ingenjörer köps in, vad de innehåller, hur de genomförs, utvärderas och vilka resultatutbildningarna leder till. Totalt intervjuades sex sjukhus runt om i Sverige där elva medicintekniska ingenjörer och fyra verksamhetschefer deltog. En kvalitativ metod användes i studien i form av semistrukturerade intervjuer som grund för att analysera frågeställningarna. Resultatet visade att utbildningar köps in i upphandling av nya ultraljudsmaskiner och genomförs under garantiåren. Utbildningarna hålls av leverantörerna och de brukar vara i två dagar. Effekterna av utbildningarna varierar och beror på vilket serviceavtal som sjukhusen har. Det saknas en formell modell för utvärdering och uppföljning, trots det faktum att det i årliga möten diskuteras hur utbildningarna har gått och vilka kompetenser som behövs. Resultatet från studien kan främst användas i syfte att skapa bättre utbildningar, underlätta kommunikationen mellan sjukhus och leverantör om vad kursen innebär, samt vad ingenjörerna föredrar för innehåll i kurser för att kunna utvecklas inom ultraljud. / This study aims to investigate how ultrasound training for engineers is purchased, including how it is carried out and evaluated, what the different courses contain and what result the courses lead to. Six hospitals around Sweden were interviewed, where eleven medical engineers and four business managers participated. A qualitative method was used in the study with semi-structured interviews as a basis for analysing the issues. The results showed that the training courses are purchased in the procurement of new ultrasound machines and are carried out during the warranty years. The suppliers hold the training courses, which are usually held for two days. The effects of training vary and depend on the service agreement that the hospitals have. There is no formal model for evaluation and follow-up, even though annual meetings discuss how the training has gone and what skills are needed. The results can mainly be used to create better training and improve communication between hospital and supplier about what the course entails and what the engineers prefer for the content of courses to develop in the area.

Syfte: Studien ämnar undersöka bostadsrättsföreningars nivå av sparande för framtida kapitalunderhåll i Gävle kommun under räkenskapsåren 2018 och 2022 samt analysera vilka faktorer som kan förklara varför somliga bostadsrättsföreningar avsätter mer i sparande än andra. Metod: Vi har tillämpat en kvantitativ metod där data från årsredovisningar samlats in och använts för att beräkna och koda studiens variabler. För att testa hypoteserna analyserades data med multipel regressionsanalys. Resultat och slutsats: De flesta bostadsrättsföreningar avsätter adekvata medel, men en betydande minoritet riskerar framtida avgiftshöjningar för att täcka kommande kapitalunderhåll. Resultaten visar två statistiskt signifikanta samband med högre sparande och indikerar andra potentiella kumulativa effekter. Examensarbetets bidrag: Användning av en ny metod för empiriinsamling, ny strategi för fastställande av population och urval, undersökning av tidigare outredda oberoende variabler samt den första studien som specifikt granskar bostadsbeståndet i Gävleområdet. Förslag till fortsatt forskning: Vi rekommenderar att framtida studier undersöker relationen mellan studiens beroende och oberoende variabler med ett större datamaterial. Ett större urval kan ge en tydligare bild av hur de oberoende variablerna påverkar bostadsrättsföreningars sparande. / Aim: This research aims to assess the savings levels for future capital maintenance by housing cooperatives in Gävle municipality during the fiscal years 2018 and 2022, and to identify the factors that contribute to higher savings in some cooperatives compared to others. Method: Using a quantitative approach, we gathered data from annual reports to calculate and code the study's variables. Multiple regression analysis was employed to test the hypotheses. Results and conclusions: While the majority of housing cooperatives set aside adequate funds, a notable minority face the risk of future fee increases to cover necessary capital maintenance. The findings reveal two statistically significant correlations with higher savings and indicate other possible cumulative effects. Contribution of the thesis: Utilizing a novel approach for data collection, a new method for defining population and sampling, analysis of previously unexamined independent variables and the first study specifically assessing the housing stock in the Gävle region. Suggestions for future research: Future research should examine the relationship between the dependent and independent variables with a more extensive dataset. Increasing the sample size may yield a better understanding of how the independent variables influence the savings of housing cooperatives.

D. Litt. et Phil. (African Politics) / This study is an exploration of transitional justice mechanisms available to post conflict communities. It is a context sensitive and sustained interrogation of the effectiveness of endogenous transitional justice mechanisms in post-colonial Zimbabwe. The study utilised Ruti Teitel’s (1997: 2009-2080) realist/idealist theory as its theoretical framework. Using the case of Africa in general and Zimbabwe in particular, it analyses the application of imported idealist transitional justice mechanisms, mainly International Criminal Court (ICC) trials. It also debates the efficacy of realist transitional justice mechanisms, mainly the South African model of a Truth and Reconciliation Commission (TRC).The study explores the application of what it terms broad realist transitional justice mechanisms used mostly in rural areas of Zimbabwe to achieve peace building and reconciliation. These modes of everyday healing and reconciliation include the traditional institutions of ngozi (avenging spirit), botso (self-shaming), chenura (cleansing ceremonies), nhimbe (community working groups) and nyaradzo (memorials). The key finding of this exploration is that local realist transitional justice mechanisms are more efficacious in fostering peace building and reconciliation than imported idealist mechanisms such as the ICC trials and imported realist mechanisms such as the TRC. More value can be realised when imported realist mechanisms and local realist transitional justice mechanisms complement each other. The study contributes to the literature on transitional justice in general and bottom-up, victim-centred reconciliation in particular. It offers a different approach to the study of transitional justice in post conflict Zimbabwe by recasting the debate away from the liberal peace paradigm which critiques state centric top-down approaches such as trials, clemencies, amnesties and institutional reform. The study considers the agency of ‘ordinary’ people in resolving the after effects of politically motivated harm. It also lays the foundation for further research into other traditional transitional justice mechanisms used for peace building and reconciliation elsewhere in Africa / Political Sciences

The moderation function of in-group status position on the relationship between group-based guilt and reparation intention was tested in a 2 (group-based guilt: low versus high) x 2 (status loss: weak versus strong) factorial between-subjects design, using an online survey software program named Qualtrics. The target population was white South African undergraduate students born after 1988 and registered at the University of South Africa. The results of the first Experiment confirmed the hypothesis, that the relationship between group-based guilt and reparation intention becomes less significant the more participants perceive a loss of status for their in-group. However, the hypothesis could not be confirmed in Experiment 2. The results are presented and discussed in detail / Psychology / M.A. (Psychology)

Sedan slutet av 1960-talet har det i lag funnits en avdragsregel som innebär att utgifter, för vissa typer av ändringsarbeten på en byggnad, kan dras av omedelbart, istället för genom årliga värdeminskningsavdrag. Regeln brukar benämnas det ”utvidgade reparationsbegreppet” och återfinns i 19 kap. 2 § 2 st. inkomstskattelagen (1999:1229). Efter att många skattskyldiga ansåg att regeln givits en alltför restriktiv tolkning i rättspraxis, genomfördes en lagändring som resulterade i att benämningen i lagtexten ändrades från ”den bedrivna näringsverksamheten” till ”den skattskyldiges näringsverksamhet”. Ändringen innebär att bedömningen av huruvida vidtagna ändringsarbeten kan anses normala i en verksamhet ska göras utifrån antingen fastighetsägarens eller hyresgästens verksamhet, beroende på vem av dem som bekostar arbetena. I juni 2016 publicerade Skatteverket ett ställningstagande i vilket redogörs för om utgifter för ändringsarbeten på en byggnad vid en ”förstagångsanpassning” av byggnaden eller dess byggnadsdel (lokal), kan vara omedelbart avdragsgilla enligt det utvidgade reparations-begreppet. Skatteverkets slutsats är att utgifter för ändringsarbeten vid en ”förstagångs-anpassning” inte är omedelbart avdragsgilla. Skatteverket har kritiserats för att i ställningstagandet tolka begreppet ”näringsverksamhet” alltför restriktivt i förhållande till lagstiftarens syfte och gällande rätt i övrigt. I föreliggande uppsats studeras det utvidgade reparationsbegreppet närmare med följande övergripande frågeställningar som utgångspunkt: Vad är gällande rätt avseende det utvidgade reparationsbegreppet? Är Skatteverkets ställningstagande och tolkning av begreppet ”näringsverksamhet” förenligt med gällande rätt? I uppsatsen kommer författaren fram till slutsatsen att Skatteverkets tolkning av begreppet ”näringsverksamhet” förefaller vara restriktivare än vad lagstiftaren åsyftar. Emellertid finner författaren likaledes att, i brist på prejudikat ifrån HFD, någon definitiv slutsats om huruvida Skatteverkets tolkning överensstämmer med gällande rätt eller ej, inte går att fastställa i dagsläget. Istället får det konstateras att rättsläget tillsvidare är oklart.

La réparation internationale de dommages individuels est un sujet assez nouveau et peu réglementé en droit des gens. Chapitre manquant du droit de la responsabilité internationale de l’État tel qu’il a été codifié par la Commission du droit international des Nations Unies dans son Projet d’articles sur la responsabilité de l’État pour fait internationalement illicite (2001), la responsabilité internationale de l’État à l’égard de l’individu trouve dans la jurisprudence de la Cour interaméricaine des droits de l’homme un environnement salutaire à son développement. Jouissant d’une compétence large en matière de réparations conférée par l’article 63§1 de la Convention américaine des droits de l’homme, la Cour interaméricaine a développé une jurisprudence très riche et originale qui fournit un ensemble coordonné de règles et principes permettant de dégager un régime juridique de la réparation de dommages individuels dans le cadre de rapports transétatiques. L’étude du régime de réparations interaméricain permet d’identifier que ses spécificités – liées à la nature transétatique du rapport de responsabilité et à la nature grave des violations qu’on retrouve dans le contentieux régional – n’impliquent pas un détournement des règles classiques de la responsabilité internationale mais plutôt leur complétion : le régime juridique de la réparation qui se dégage de la jurisprudence de la Cour interaméricaine contribue définitivement à combler les lacunes du droit des gens ayant trait à la discipline de la réparation internationale de dommages soufferts par des personnes privées. / The international reparation of damages suffered by individuals is a relatively new subject that hasn´t received the amount of attention it deserves from international law. The international responsibility of the State towards individuals is indeed a topic missing from the Draft articles on responsibility of States for internationally wrongful acts adopted in 2001 by the United Nations International Law Commission, which was mainly featured to discipline the responsibility of a State towards another State. The jurisprudence of the Inter - American Court of Human Rights might considerably contribute to filling this important gap in the law of international responsibility. Taking advantage of its large competence to order reparation measures according to article 63§1 of the American Convention of Human Rights, the Inter-American Court has developed a substantial and original jurisprudence leading to the establishment of a legal regime on the reparation of individual damages on the basis of the international responsibility of the State. From the study of the inter -american regime on reparations, it can be inferred that its specificities – deriving from the particular character of the State responsibility towards the individual and from the seriousness of the human rights violations brought to the Court – do not lead to a diversion from the general rules on State responsibility, but rather to their completion: the legal regime of reparation that comes out from the jurisprudence of the Inter-American Court definitely contributes in filling the lacunas of international law with regards to the discipline of the international reparation of damages caused to private persons.

In recent years the field of reparations for indigenous peoples has increased remarkably. Past wrongs made by states in the distant past has become more important to highlight, not only because of the memories of historical injustice, but because of how the past impacts the future, and not least, still appears as structures of discrimination remaining from the past.   As an indigenous people the Saami people living in Sweden have experiences of both historical injustices as well as todays struggle with discrimination on different levels. Mostly regarding their right to be a part of decisions concerning them and the right of culture, language, identity, land and nature resources, fundamental for them as a people. In order to change their situation and to search for redress the Saami people in Sweden have announced their need of a truth commission. The Saami people are not the first indigenous people whom search for redress through a truth commission, but is it possible to learn from others?   With this in mind, my study aim to look at practical experiences of truth commissions in Canada and New Zealand and further, examine what the Saami people in Sweden hope to achieve with a truth commission. Thereafter, I weight other indigenous peoples experiences of a truth commission with the Saami peoples expectations to find out what keys need to be considered to increase the outcome of a truth commission. Where theory, practical experience and Saami expectations connects is where the key issues can be found. Given this, my study suggests that five different key issues must be thought through and shall not be underestimated as they may have an effect on the ongoing process as well as on the results and the aftermaths. The key issues that is suggested is as follows: 1) political will, 2) the role and engagement of Civil Society, 3) the Saami´s own involvement 4) the problem of what focus the commission should have, and 5) the awareness of “tough” questions coming up.

Introduction Le cancer bronchique est un problème de santé publique en étant la première cause de décès par cancer dans le monde. Il reste de mauvais pronostic avec une résistance au Cisplatine qui est inéluctable dans l’histoire naturelle de la maladie. Nous nous sommes intéressés à l’association du CDDP aux inhibiteurs de la Poly(ADP-ribose) polymérase. Les inhibiteurs pharmacologiques de PARP sont source d’optimisme en oncologie clinique en monothérapie pour des tumeurs déficientes pour une voie de réparation de l’ADN et en association aux cytotoxiques classiques.Matériel et méthodes Nous avons généré 9 clones résistants au CDDP après culture de la lignée A549 dans des faibles doses de CDDP. Deux inhibiteurs pharmacologiques de PARP, CEP8983 (CEP) et PJ34 (PJ), ainsi que des siRNA spécifiques de PARP1 sont utilisés pour l’inhibition de PARP. L’apoptose est mesurée en cytométrie de flux par l’intermédiaire du potentiel membranaire de la mitochondrie DiOC6(3) et la perméabilisation de la membrane plasmique est évaluée par l’iodide de propidium. Le test de clonogénicité permet d’évaluer la capacité des cellules à échapper à la mort et à former une colonie. L’activité métabolique des cellules est mesurée par la mesure de clivage du sel de tetrazolium WST-1. L’immunofluorescence sur cellules fixées a permis d’étudier les dommages de l’ADN (γH2AX), la voie intrinsèque de l’apoptose (l’activation de la caspase 3 et la libération du cytochrome c) et la recombinaison homologue (BRCA1, RAD51). En Western Blot nous avons mesuré l’expression et l’activité de PARP (PAR) ainsi que l’expression d’acteurs de la réparation par excision de base (BER) (XRCC1 and polymérase β). Nous avons développé une méthode de détection de PAR en immunohistochimie sur des tissus inclus en paraffine. Résultats Nous avons trouvé un effet synergique pour l’association du CDDP aux inhibiteurs de PARP in vitro. De façon inattendue nous avons observé que les clones résistants au CDDP développent une addiction à PARP et sont spécifiquement tués par l’inhibition de PARP contrairement à la lignée parentale. Ces clones exhibent une hyperexpression et une hyperactivité de PARP. La réponse aux inhibiteurs de PARP corrèle plus précisément avec l’activation plutôt qu’avec l’expression de PARP, pointant que PAR est un biomarqueur plus précis que PARP. Nous avons observé que l’hyperactivation de PARP accompagne une résistance induite au CDDP et prédispose à une sensibilité aux inhibiteurs de PARP dans d’autres lignées de cancer bronchique (H460 et H1650), de mésothéliome (P31), de cancer de l’ovaire (TOV112D) et de col (HeLa). Dans des expériences in vivo nous avons noté que dans les xénogreffes obtenues à partir de clones résistants au CDDP, l’expression de PAR est stablement retrouvée en immunohistochimie. Ces tumeurs répondaient à l’inhibition de PARP par le PJ en diminuant l’expression de PAR. Les clones résistants au CDDP sensibilisés aux I PARP ont une recombinaison homologue conservée, cependant ont un déficit dans les étapes terminales du BER.Conclusion Nous avons identifié un effet synergique pour l’association des inhibiteurs de PARP au CDDP de des lignées de cancer bronchique. Nous avons observé une dépendance à PARP dans des lignées de cancer bronchique résistantes au CDDP et déficientes pour l’élongation du BER. Nous postulant que PAR est un biomarqueur spécifique de la réponse aux inhibiteurs de PARP. / Introduction Driven by the facts that non small cell lung cancer (NSCLC) is the leading cause of cancer-related morbidity and mortality worldwide and that NSCLC patients often develop resistance against Cisplatin (CDDP)-based therapies, we addressed the question of the combination therapy of CDDP with poly(ADP-ribose) polymerases (PARP) inhibitors. Inhibitors of PARP have raised great expectations for the treatment of a variety of cancers, either as monotherapeutic agent against DNA repair-deficient tumours or combined to DNA-damaging compounds.Material and methods We generated nine CDDP-resistant clones by prolonged exposure to low dose CDDP of the A549 NSCLC parental cell line. Two distinct PARP inhibitors, CEP8983 (CEP) and PJ34 (PJ) as well as PARP1 knockdown with small interfering RNAs (siRNAs) were used for PARP inhibition. Apoptosis was measured by the simultaneous assessment for the loss of the mitochondrial transmembrane potential (m) and the breakdown of the plasma membrane using the m-sensitive fluorochrome DiOC6(3) and the vital dye propidium iodide, respectively. Moreover clonogenic survival was assessed. In vitro assessments of the enzymatic activity of cells were based on the reduction of the colorless tetrazolium salt. Immunofluorescence microscopy determinations were performed with antibodies specific for DNA damage (γH2AX), intrinsic apoptosis (cleaved Caspase-3 and cytochrome c), and homologous recombination (RAD51 and BRCA1). Immunoblotting was assed for PARP1 expression and activity (PAR) and base excision repair (BER) effectors (XRCC1 and polymerase β). We developed an immunohistochemical staining method that specifically detects PAR on paraffin-embedded cell pellets and tissue sections.Results We found that PARP inhibitors and PARP1 siRNAs synergized with CDDP in the killing of NSCLC cells in vitro. Unexpectedly, CDDP-resistant NSCLC cell clones developed addiction to PARP hyperactivation, thereby becoming susceptible to apoptosis induction by PARP inhibition. We showed that these cisplatin-resistant clones, exhibited high PARP protein levels and increased PARP activity, leading to an increased poly-ADP ribosylation of cellular proteins, as compared to their parental, cisplatin-sensitive counterparts. These cisplatin-resistant cells become susceptible to cell death as induced by PARP inhibition, correlating with the hyperactivity of PARP (elevated PAR levels) more accuratly than with the overexpression of PARP. Suggesting that PAR levels may constitute a more accurate biomarker than PARP to predict the sensitivity of cells to PARP inhibition. We expanded the observation that cisplatin resistance causes PARP upregulation and hyperactivation and subsequent sensitization to PARP inhibition to additional five human cancer cell lines including two NSCLC (H1650 and H460), one mesothelioma (P31), one ovarian (TOV112D) and one cervical cancer (HeLa) cell line. To get further insight into this issue, we generated in vivo experiments. Tumors derived from CDDP-resistant cells were characterized by elevated levels of PAR suggesting that PAR levels are preserved during tumor formation. Those PAR-overexpressing tumors responded to the administration of PJ in vivo with a consistent reduction in PAR immunoreactivity. CDDP resistant clones that are specifically killed by PARP inhibitors assessed efficient homologous recombination repair however deficient BER elongation.Conclusion We showed a beneficial effect for the association therapy of PARP inhibitors with CDDP in several NSCLC cell lines. We have identified an addiction to PARP in CDDP resistant cell lines with deficient BER elongation. We postulate that PAR is a specific predictive biomarker for the response to PARP inhibitors.

La question de la justice dans les sociétés en transition est systématiquement soulevée après un conflit ou une période répressive ou autoritaire. En effet, les violations flagrantes du droit international des droits de l’homme et les violations graves du droit international humanitaire perpétrées sous les précédents régimes ne sauraient laisser aux institutions politiques nouvelles le choix de l’inaction face au passé. Les commissions vérité et réconciliation constituent un des mécanismes de la justice transitionnelle qui place la victime au cœur de ses préoccupations notamment parce que l’incrimination du bourreau n’est pas le seul objectif de la justice et que, comme le remarquait Hannah Arendt, il faut bien constater qu’il y a « des crimes qu’on ne peut ni punir, ni pardonner ». Parfois présentées comme une solution alternative à la justice pénale, ces commissions ont pour objectif d’établir les méfaits des anciens régimes. Le possible choix entre les commissions vérité et la justice répressive interne ou internationale est écarté dans cette étude qui entend accorder une place importante à la complémentarité des commissions vérité et réconciliation avec les autres mécanismes de la justice transitionnelle, notamment les poursuites judiciaires contre les auteurs des crimes de droit international les plus graves et les réparations pour les victimes. De fait, le but de cette étude n’est pas d’analyser de manière isolée ces commissions mais de constater que les normes internationales et la situation propre à chaque pays en transition limitent les options disponibles du traitement du passé. La recherche est fondée sur la méthode d'étude de cas de plusieurs pays dans une démarche comparative afin d’en tirer des conclusions aboutissant à démontrer la légitimité des commissions vérité et réconciliation en période de transition ainsi que leur fonctionnement. / The issue of justice in societies in transition is systematically raised after a conflict, a repressive period or an authoritarian period. Gross violations of international human rights law and grave breaches of international humanitarian law perpetrated under previous regimes cannot let the choice of inaction concerning the past to the new political institutions.Truth and reconciliation commissions constitute one of the mechanisms of transitional justice, which place the victim at the middle of its concerns especially because the criminalization of perpetrators is not the only goal of justice and, as noted by Hannah Arendt, “men are unable to forgive what they cannot punish and are unable to punish what turns out to be unforgivable”. Sometimes presented as an alternative mean to criminal justice, these commissions aim to establish the misdeeds committed by former regimes. The possible choice between truth commissions and international or internal criminal Justice is avoided in this study, which aims to highlight the important role of the complementarity of truth and reconciliation commissions with other transitional justice mechanisms, notably legal prosecutions against the perpetrators of crimes against international law and reparations for victims. In this regard, the aim of this study is not to analyze these commissions in an isolated manner, but to notice that international standards as well as situations in each country restrict the options available for dealing with the past. This research is based on a comparative approach presenting a case study on different countries for demonstrate the legitimacy of truth and reconciliation commissions and their functioning in period of transition.