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Risques épigénétiques de la procréation médicalement assistée : enjeux éthiques pour les parents, les futurs enfants et les professionnels de la santéRoy, Marie-Christine 06 1900 (has links)
La procréation médicalement assistée (PMA) permet à beaucoup d’individus infertiles de concevoir un enfant qui leur est génétiquement lié. Cependant, des données scientifiques émergentes suggèrent que la PMA pourrait entraîner des risques épigénétiques pour les futurs enfants. Conformément à l'hypothèse des origines développementales de la santé et des maladies, la PMA pourrait augmenter le risque de développer des maladies à apparition tardive par des mécanismes épigénétiques, car l’hyperovulation, les méthodes de fécondation et la culture embryonnaire pourraient nuire à la reprogrammation épigénétique de l'embryon. De tels risques épigénétiques soulèvent des enjeux éthiques pour toutes les parties prenantes: les futurs parents et enfants, les professionnels de la santé, et la société. Ce mémoire se concentre sur les questions éthiques soulevées par la prise en compte de ces risques lors de l'utilisation de la PMA. Pour mettre en lumière ces enjeux, nous utilisons l’approche principiste. Nous argüons qu'une tension éthique peut émerger entre le respect de l'autonomie procréative des parents d’intention et le devoir de minimiser les risques pour les enfants potentiels. Une seconde tension éthique peut émerger entre le droit des parents d’intention de faire un choix éclairé, et la réticence que peuvent avoir les professionnels de la santé de communiquer l’information sur les risques épigénétiques de la PMA, étant donné la validité incertaine de ces informations. Nous explorons aussi le risque de conflits d’intérêts pour les cliniciens des cliniques de PMA.
Nous soutenons que les parents d’intention et les professionnels de la santé ont la responsabilité partagée de promouvoir les meilleurs intérêts du futur enfant. Nous plaidons pour que plus de recherche soit faite sur les effets de la PMA sur la santé des futurs enfants, pour que soient énoncées des lignes directrices priorisant le recours à des techniques moins risquées au niveau épigénétique, et pour que d’autres lignes directrices guident les professionnels de la santé dans la communication des risques épigénétiques associés à la PMA. Enfin, nous suggérons que cette communication se fasse dans le cadre d’une approche centrée sur le patient. Nous explorons aussi l’apport d’une approche narrative pour aborder les tensions éthiques soulevées par l’approche principiste. / The use of assisted reproductive technologies (ART) allows many coping with infertility to conceive. However, an emerging body of evidence suggests that ART could carry epigenetic risks for those conceived through the use of these technologies. In accordance with the Developmental Origins of Health and Disease (DOHaD) hypothesis, ART could increase the risk of developing late-onset diseases through epigenetic mechanisms, since superovulation, fertilization methods and embryo culture could impair the embryo’s epigenetic reprogramming. Such epigenetic risks raise ethical issues for all stakeholders: prospective parents and children, health professionals, and society. This thesis focuses on ethical issues raised by the consideration of these risks when using ART. To highlight these issues, we use the principlist approach. We argue that an ethical tension can emerge between respect for the reproductive autonomy of prospective parents and the duty to minimize the risks for potential children. A second ethical tension can emerge between the parents' right to make an informed choice about the use of ART, and the reluctance of health professionals to communicate epigenetic risk given its uncertain validity. We also explore the risks of conflicts of interests for health professionals in ART clinics.
We argue that prospective parents and health professionals have a shared responsibility to promote the best interests of the future child. We also argue in favor of further research on the effects of ART on the health of future children, and in favor of clinical guidelines that prioritize the use of techniques that carry less epigenetic risk and that assist health professionals in communicating the epigenetic risks associated with ART. Finally, we suggest that this communication be done within the patient-centered approach. We also explore the contribution of a narrative approach to address the ethical tensions raised by the principlist approach.
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L'autoconservation des ovocytes : l'infertilité anticipée comme mode de gestion de l'horloge biologiqueGervais, Maude 04 1900 (has links)
Ce mémoire porte sur les représentations sociales de la maternité présentes dans les discours publicitaires entourant la pratique de l’autoconservation des ovocytes. C’est à travers l’analyse de discours promotionnel des cliniques de fertilité que je montrerai comment cette pratique reproduit une vision idéalisée de la maternité et de la procréation. L’autoconservation des ovocytes promet aux femmes de prolonger leur capacité procréative au-delà de la temporalité biologique. Avec la transformation des modes de vie, des valeurs et des exigences professionnelles, un écart sociologique important s’est instauré, pour plusieurs femmes, entre la fertilité biologique et la fertilité sociale. On assiste alors à la marchandisation de la temporalité biologique dans le but de réaliser certains idéaux professionnels et affectifs. La littérature est abondante sur les raisons qui poussent les femmes à s’engager dans le processus de l’autoconservation des ovocytes, mais peu de recherches s’intéressent à la manière dont les normes en matière de maternité sont produites et reproduites à travers l’usage des technologies de la reproduction. Dans ce mémoire, je souhaite porter une réflexion tant sur les valeurs promues par les cliniques de fertilité que sur les impacts inattendus de la pratique de l’autoconservation des ovocytes sur la culture reproductive et sur le rapport au corps féminin, tout en considérant les enjeux socio-économiques qu’elle sous-tend. Je montrerai que l’industrie de la préservation de la fertilité révèle un tout nouveau rapport au temps productif et au temps reproductif. / This thesis focuses on the social representations of motherhood present in advertising discourse
surrounding the practice of social egg freezing. It is through the analysis of promotional discourse
from fertility clinics that we will show how this practice reproduces an idealized vision of
motherhood and procreation. The self-preservation of oocytes aims to allow women to extend their
reproductive capacity beyond biological temporality. The transformation of lifestyles, values and
professional requirements caused a significant sociological gap between biological fertility and
social fertility. We are then witnessing the commodification of biological temporality in order to
realize certain professional and emotional ideals. The literature is plentiful on the reasons that lead
women to engage in the process of social egg freezing, but little research is focused on how
standards in maternity are produced and reproduced throughout the use of egg freezing and the use
of reproductive technologies. In this thesis, we wish to reflect both the values promoted by fertility
clinics and the unexpected impacts of the practice of social egg freezing on reproductive culture as
well as the relationship to the female body, while considering the socio-economic issues that it
underlies.
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Christian kinship : relatedness in Christian practice and moral thoughtTorrance, David Alan January 2017 (has links)
Ideas of kinship play a significant role in structuring everyday life, and yet kinship has been neglected in Christian ethics, as well as moral philosophy and bioethics. Attention has been paid in these disciplines to the ethics of ‘family,’ but little regard has been paid to the fact that kinship is not a given, but is culturally contingent. The thesis seeks to remedy the neglect in recent Christian theological ethics by drawing on resources from the history of Christian thought and practice. It uses social anthropology both to unsettle the accounts of kinship used in Christian ethics, and to expose elements in Christian traditions of thought and practice relating to kinship. Notions of shared bodily substance, the house, gender and personhood recur cross-culturally in giving shape to kinship. By examining these four notions as they inform Christian thought and practice, a theological account is developed. Chapters dedicated to each of these four attempt to provide, in the first instance, a descriptive account of how the notion has structured Christian thought and practice in relation to kinship. Each chapter then turns, in the second instance, to a critical mode, offering a theological treatment of the chapter topic as it bears on kinship. The thesis concludes that kinship in Christ should be considered normatively primary for the Christian, but also that there are ways in which Christians have honoured this kinship in Christ by organising and playing out kinship on a smaller scale. In detailing the distinctively Christian organising principles that structure some practices of kinship ‘in miniature,’ another common practice – the special privileging of the blood tie in structuring kinship – is singled out for critique.
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Building families through Assisted Reproductive Technologies in South Africa: a critical legal analysisMande, Ntumba 02 1900 (has links)
The advent of ARTs has enabled many individuals to have children and build families. Although ARTs have from the start been designated to serve as alternative way for heterosexual infertile individuals and couples to have genetically related children, ARTs are nowadays widely used by gays and lesbians to have even genetically unrelated children and build their families. This study addresses the well-being of children born as a result of ARTs and growing up in homosexual families in South Africa. South Africa has legalised homosexual unions, granting gays and lesbians several rights, including the right to marry, use ARTs to reproduce, and build families in which they raise their children. South Africa has also provided constitutional and statutory protection of children’s rights and has further required that the child’s best interests be considered as paramount in every matter concerning the child. Although ARTs may have allowed people to have children, they have proven to put the child’s interests at risk. ARTs are associated with several physical and psychological problems for resulting children. The legal protection provided for those children seems to be inadequate in respect of their best interests. Unlike Australian statutes that have provided strong protection for the child’s best interests, South African legislations regulating ARTs are far from protecting ART-born children’s interests. The application of the child’s best interests criterion to ART procedures has revealed that in the USA and Australia efforts of the state, ART providers and parents have been centred on the transfer of the custody of the ART-born child to the commissioning parent(s). Although in South Africa the application of the child’s best interests in the context of surrogacy procedures has revealed the protection of the child’s interests, it should be noted that that protection seems to focus on the child’s post-birth period. This situation leaves ART-born children without any protection, especially before their birth. In order to give effect to section 28 of the Constitution of the Republic of South Africa, 1996 and protect ART-born children’s interests, I make certain proposals for law reform in the final chapter of this thesis. / Private Law / LL. D
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Exorcising Intersex and Cripping Compulsory DyadismOrr, Celeste E. 08 May 2018 (has links)
Using hauntology as a linchpin, this dissertation explores the undertheorized connection between intersex and disability. Building on important feminist research in the fields of intersex, queer, disability, crip, and hauntology studies, I ask, how do we understand and reconcile the contested meanings, responses to, and effects of intersex? Intersex is “a perpetually shifting phantasm” (Holmes 2002: 175), yet intersex is typically represented and treated as innate disorder, disability, or disease by medical professionals. That said, many intersex people appear to distance from disability. By engaging intersex studies with feminist disability and crip theories, however, I demonstrate that an intersex politic and intersex studies must be rooted in a disability politic and disability studies.
Through a feminist disability and crip lens, I conduct a textual and critical discourse analysis of three case studies of interphobic violence or, what I term, “compulsory dyadism,” meaning the instituted cultural mandate that people cannot have intersex traits or house the “spectre of intersex” (Sparrow 2013: 29); such a spectre must be exorcised. The three case studies include nonconsensual medical interventions, sport sex testing, and employing reproductive technologies to select against intersex variations. My analyses of these case studies produce three important observations. First, intersex is presently and effectively being integrated into conventional notions of disability; second, ableist logics underpin interphobic violence; and third, compulsory dyadism is intertwined with, or is an iteration of, compulsory able-bodiedness. In recognizing this interconnection, theorizing intersex and disability together is not merely beneficial, doing so is necessary. Ultimately, my dissertation interrogates and extends questions of the ever-shifting categorization of body-minds, culturally mandated ways of being, and (the haunting effects of) pathologization. I apply pressure to the academic field of intersex studies as well as intersex activist and advocate communities to center disability in discussions concerning intersex human rights and interphobia.
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Récits de québécoises sur leur utilisation des Nouvelles Technologies de Reproduction afin de combler leur désir de parentalitéLalonde, Marie-Claude 08 1900 (has links)
Avec toutes les technologies disponibles afin de pallier à l’infertilité de nos jours, il peut sembler qu’avoir un enfant est chose simple. Toutefois, les discours de quinze québécoises rencontrées, qui ont vécu ou vivent toujours de l’infertilité, démontrent que le parcours en procréation médicalement assistée est semé d’embûches. Comme le dit Félicia, une femme rencontrée: «l’infertilité ça l’affecte plein, plein de sphères de la vie». L’un des objectifs de ce travail est d’ailleurs de questionner le choix de ces femmes d’aller en clinique de fertilité lorsque des difficultés à procréer ont été rencontrées et de soulever les impacts de ce choix. Cette recherche démontrera que les québécoises et les choix qu’elles prennent dans le domaine reproducteur sont profondément influencés par les pressions sociales et le mode de pensée propre à leur société. / With the technologies available in order to mitigate infertility, it would seem that having a child would be easy. However, the dialogue of fifteen Quebecers that are dealing with or have dealt with infertility illustrates that the process of medically assisted procreation has its pitfalls. As explained by Felicia, "Infertility affects many, many spheres of life". One objective of this work is to question the choice of women who go to fertility clinics when difficulties to procreate arise and to outline the impacts of their choice. This research will demonstrate that Quebecers and the choices they make in the reproductive field are profoundly influenced by social pressures and the way of thinking of their society.
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Surrogatmodern och den mänskliga värdigheten : En diskursanalys av den statliga utredningen om surrogatmoderskap, ur ett kritiskt postkolonialt feministiskt perspektivZanzi Ferrando, Diana January 2019 (has links)
Uppsatsen undersöker hur ”SOU 2016:11 Olika vägar till föräldraskap” formulerar problemet med surrogatmoderskap, vilka subjektspositioner som kan urskiljas i utredningen och analyserar den ut ett kritiskt postkolonialt feministiskt perspektiv. Utredningen utgår ifrån mänsklig värdighet, autonomi och barnets bästa vilket uppsatsen belyser får konsekvenser för hur problemet med surrogatarrangemang porträtteras olika beroende på om surrogatmodern och barnet är från det globala syd eller det globala nord. Utgångspunkterna är centrala när surrogatmodern och barnet från det globala nord lyfts men får inte samma roll gällande surrogatmodern och det barn hon föder. Vidare undersöks hur subjektspositioner formuleras utifrån emotionell/icke-emotionell, sårbar/icke-sårbar, skyddsvärd/icke-skyddsvärd och blottlägger hur den svenska surrogatmodern och det inrikesfödda barnet konstrueras som emotionella, sårbara och skyddsvärda vilket skiljer sig från hur den utländska surrogatmodern och det utrikesfödda barnet konstrueras. Dessa omges att tystnad vilket får konsekvenser för hur de porträtteras och för vilka åtgärder som föreslås. Uppsatsen bidrar till en utveckling av tidigare forskning med ett tillägg av nyckelordet skyddsvärd för att undersöka konstrueringen av surrogatmödrar. Uppsatsen visar att begreppet är relevant genom att materialet visat på delvis konstuering av emotionell och sårbar men inte skyddsvärd och att detta påverkat resultat och åtgärder. Vidare stärker uppsatsen tidigare forskning som menar att utgångspunkten mänsklig värdighet verkar för en avhumanisering av surrogatmödrar från det globala syd samt att synen på biologi varierar beroende på var ett barn föds. Uppsatsen bygger vidare på tidigare forskning som menar att uttryckt rationalitet och brist på emotion resulterar i en avhumanisering, genom att blottlägga hur det kan räcka med att subjektspositionerna möts av tysthet för att uppnå samma resultat. Detta arbete belyser hur olika subjektspositioner framställs olika i den statliga utredningen och hur koloniala idéer hänger kvar och påverkar underlag till svensk lagstiftning, samt blottlägger vilka konkreta konsekvenser detta kan få för lagförslag och för surrogatmödrar i det globala syd samt de barn de föder.
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